dichloroacetic acid has been researched along with fluorouracil in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| He, J; Li, J; Liang, H; Pan, F; Tong, J; Xie, G | 1 |
| Ham, IH; Han, SU; Hur, H; Kim, YB; Lee, G; Shim, W; Xuan, Y; Yun, J | 1 |
| Huang, WD; Shen, SY; Zheng, MF | 1 |
| Cho, YK; Ham, IH; Han, SU; Hur, H; Kim, YB; Lee, G; Lee, JY; Shim, W; Xuan, Y; Yun, J | 1 |
| Abánades Lázaro, I; Abánades Lázaro, S; Forgan, RS | 1 |
| Gaiddon, C; Gross, I; Gu, Y; Hou, L; Hou, Y; Huang, X; Li, L; Li, Y; Liang, Y; Luo, M; Meng, X; Wang, J; Wang, Y; Weng, X; Wu, T; Yao, M; Zhu, D; Zhu, L; Zou, H | 1 |
| Alboghobeish, S; Behmanesh, B; Khodayar, MJ; Mahdavinia, M; Nikravesh, H; Teimoori, A; Zeidooni, L | 1 |
8 other study(ies) available for dichloroacetic acid and fluorouracil
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Synergistic antitumor effect of dichloroacetate in combination with 5-fluorouracil in colorectal cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Dichloroacetic Acid; Drug Synergism; Fluorouracil; Humans; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase | 2011 |
Expression of pyruvate dehydrogenase kinase-1 in gastric cancer as a potential therapeutic target.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Aged; Antimetabolites, Antineoplastic; Blotting, Western; Carcinoma, Signet Ring Cell; Cell Survival; Dichloroacetic Acid; Female; Fluorouracil; Glucose; Glucose Transporter Type 1; Glycolysis; Hexokinase; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoenzyme Techniques; Lactic Acid; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Invasiveness; Prognosis; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Stomach Neoplasms; Survival Rate; Tissue Array Analysis; Tumor Cells, Cultured | 2013 |
DCA increases the antitumor effects of capecitabine in a mouse B16 melanoma allograft and a human non-small cell lung cancer A549 xenograft.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Deoxycytidine; Dichloroacetic Acid; Dose-Response Relationship, Drug; Drug Synergism; Female; Fluorouracil; Humans; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasm Proteins; Prodrugs; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Random Allocation; Thymidine Phosphorylase; Xenograft Model Antitumor Assays | 2013 |
Dichloroacetate attenuates hypoxia-induced resistance to 5-fluorouracil in gastric cancer through the regulation of glucose metabolism.
Topics: Adult; Aged; Cell Hypoxia; Cell Line, Tumor; Dichloroacetic Acid; Down-Regulation; Drug Resistance, Neoplasm; Drug Synergism; Female; Fluorouracil; Glucose; Glycolysis; Humans; Male; Metabolic Networks and Pathways; Middle Aged; Stomach Neoplasms | 2014 |
Enhancing anticancer cytotoxicity through bimodal drug delivery from ultrasmall Zr MOF nanoparticles.
Topics: Antineoplastic Agents; Cell Proliferation; Cell Survival; Dichloroacetic Acid; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Screening Assays, Antitumor; Fluorouracil; Humans; MCF-7 Cells; Metal-Organic Frameworks; Models, Molecular; Molecular Structure; Nanoparticles; Structure-Activity Relationship; Zirconium | 2018 |
Dichloroacetate restores colorectal cancer chemosensitivity through the p53/miR-149-3p/PDK2-mediated glucose metabolic pathway.
Topics: Animals; Apoptosis; Base Sequence; Colorectal Neoplasms; Dichloroacetic Acid; Drug Resistance, Neoplasm; Fluorouracil; Glucose; HCT116 Cells; Humans; Male; Mice; MicroRNAs; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Tumor Suppressor Protein p53 | 2020 |
The combined effect of dichloroacetate and 3-bromopyruvate on glucose metabolism in colorectal cancer cell line, HT-29; the mitochondrial pathway apoptosis.
Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Dichloroacetic Acid; Drug Synergism; Fluorouracil; Glucose; HT29 Cells; Humans; Membrane Potential, Mitochondrial; Metabolic Networks and Pathways; Mitochondria; Models, Biological; Pyruvates | 2021 |