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dichloro(1,2-bis(4-hydroxyphenyl)ethylenediamine)platinum ii and diethylstilbestrol

dichloro(1,2-bis(4-hydroxyphenyl)ethylenediamine)platinum ii has been researched along with diethylstilbestrol in 1 studies

*Diethylstilbestrol: A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen. (Merck, 11th ed) [MeSH]

*Diethylstilbestrol: A synthetic nonsteroidal estrogen used in the treatment of menopausal and postmenopausal disorders. It was also used formerly as a growth promoter in animals. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen. (Merck, 11th ed) [MeSH]

Compound Research Comparison

Studies
(dichloro(1,2-bis(4-hydroxyphenyl)ethylenediamine)platinum ii)
Trials
(dichloro(1,2-bis(4-hydroxyphenyl)ethylenediamine)platinum ii)
Recent Studies (post-2010)
(dichloro(1,2-bis(4-hydroxyphenyl)ethylenediamine)platinum ii)
Studies
(diethylstilbestrol)
Trials
(diethylstilbestrol)
Recent Studies (post-2010) (diethylstilbestrol)
12008,585322491

Protein Interaction Comparison

ProteinTaxonomydichloro(1,2-bis(4-hydroxyphenyl)ethylenediamine)platinum ii (IC50)diethylstilbestrol (IC50)
high affinity choline transporter 1 isoform aHomo sapiens (human)12.5893
Estrogen receptorHomo sapiens (human)0.1312
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)3.67
Adenosine receptor A3Homo sapiens (human)2.208
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)2.963
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)2.208
Substance-K receptorHomo sapiens (human)9.553
D(1A) dopamine receptorHomo sapiens (human)7.763
Prostaglandin G/H synthase 1Homo sapiens (human)5.6
Sodium-dependent noradrenaline transporter Homo sapiens (human)3.67
Thromboxane-A synthase Homo sapiens (human)4.359
5-hydroxytryptamine receptor 2AHomo sapiens (human)4.79
Adenosine receptor A2aHomo sapiens (human)9.013
Adenosine receptor A1Homo sapiens (human)2.856
Mu-type opioid receptorHomo sapiens (human)5.778
D(3) dopamine receptorHomo sapiens (human)8.796
Delta-type opioid receptorHomo sapiens (human)2.718
Kappa-type opioid receptorHomo sapiens (human)4.563
5-hydroxytryptamine receptor 2BHomo sapiens (human)3.14
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)2.208
Sodium-dependent dopamine transporter Homo sapiens (human)1.071
Aldehyde oxidaseHomo sapiens (human)0.46
Estrogen receptor betaHomo sapiens (human)0.1588
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)0.5

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bernhardt, G; Schlemmer, R; Schönenberger, H; Spruss, T1

Other Studies

1 other study(ies) available for dichloro(1,2-bis(4-hydroxyphenyl)ethylenediamine)platinum ii and diethylstilbestrol

ArticleYear
[meso-1,2-bis(2,6-dichloro-4-hydroxyphenyl) ethylenediamine]dichloroplatinum(II), a compound with a specific activity on hormone-sensitive breast cancers--evidence for a diethylstilbestrol-like mode of action.
    Archiv der Pharmazie, 1999, Volume: 332, Issue:2

    Topics: Animals; Antineoplastic Agents, Hormonal; Diethylstilbestrol; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Neoplasms, Hormone-Dependent; Organoplatinum Compounds; Ovariectomy; Receptors, Estrogen

1999