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dicarbethoxydihydrocollidine and phenobarbital

dicarbethoxydihydrocollidine has been researched along with phenobarbital in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199015 (65.22)18.7374
1990's8 (34.78)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Atsmon, A; Epstein, O; Schoenfeld, N1
Bhutani, LK; Bikhchandani, R; Deshpande, SG; Kandhari, KC; Narang, BS1
Kimmett, SM; Mackie, JE; Marks, GS; McCluskey, SA; Riddick, DS; Whitney, RA1
Atsmon, A; Mamet, R; Mevasser, R; Schoenfeld, N1
Marks, GS; McGilvray, I; Riddick, DS1
Marks, GS; Riddick, DS1
Atsmon, A; Bomstein, Y; Mamet, R; Mevasser, R; Schoenfeld, N1
Gelboin, HV; Marks, GS; Park, SS; Riddick, DS2
Elliott, WH; Hobbs, AA; Mattschoss, LA; May, BK; Williams, KE1
Correia, MA; Lunetta, JM1
De Matteis, F; Lock, EA; Reed, CJ1
Marks, GS; McCluskey, SA; Racz, WJ; Sutherland, EP1
Bornheim, L; Caldera, P; Correia, MA; Decker, C; Rettie, AE; Sugiyama, K; Trager, WF; Wrighton, SA1
Black, KA; Coffman, BL; Dannan, GA; Green, MD; Guengerich, FP; Tephly, TR1
De Matteis, F; Harvey, C; Martin, SR1
Augusto, O; Beilan, HS; Ortiz de Montellano, PR1
Borthwick, IA; Brooker, JD; Elliott, WH; May, BK; Srivastava, G1
De Matteis, F; Gibbs, AH; Hollands, C1
Atsmon, A; Beigel, Y; Epstein, O; Greenblat, Y; Lahav, M; Schoenfeld, N1
Brooker, JD; Elliott, WH; Lim, LK; May, BK; Srivastava, G1
Kimmett, SM; Marks, GS; McNamee, JP2

Other Studies

23 other study(ies) available for dicarbethoxydihydrocollidine and phenobarbital

ArticleYear
The effect of beta-adrenergic blocking agents on experimental porphyria induced by 3,5-diethoxycarbonyl-1,4-dihydrocollidine (DDC) in vivo and in vitro.
    Biochimica et biophysica acta, 1976, Aug-24, Volume: 444, Issue:1

    Topics: 5-Aminolevulinate Synthetase; Adrenergic beta-Antagonists; Aminolevulinic Acid; Animals; Chick Embryo; Dicarbethoxydihydrocollidine; Liver; Male; Phenobarbital; Porphobilinogen; Porphyrias; Porphyrins; Propranolol; Pyridines; Rats

1976
Study of the effects of certain drugs on experimental porphyria in rats.
    Dermatologica, 1977, Volume: 154, Issue:5

    Topics: Animals; Chloroquine; Dicarbethoxydihydrocollidine; Ethanol; Griseofulvin; Liver; Phenobarbital; Porphyrias; Porphyrins; Rats; Time Factors

1977
Inactivation of cytochrome P450 and inhibition of ferrochelatase by analogues of 3,5-diethoxycarbonyl-1,4-dihydro-2,4,6-trimethylpyridine with 4-nonyl and 4-dodecyl substituents.
    Canadian journal of physiology and pharmacology, 1992, Volume: 70, Issue:8

    Topics: Animals; Chick Embryo; Cytochrome P-450 Enzyme Inhibitors; Dicarbethoxydihydrocollidine; Ferrochelatase; Heme; In Vitro Techniques; Liver; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Sprague-Dawley; Zinc

1992
Experimental latent and acute porphyria in the non-fasted rat; preventive effect of propranolol.
    Scandinavian journal of clinical and laboratory investigation, 1991, Volume: 51, Issue:8

    Topics: Acute Disease; Allylisopropylacetamide; Aminolevulinic Acid; Animals; Coproporphyrins; Dicarbethoxydihydrocollidine; Feces; Male; Phenobarbital; Porphobilinogen; Porphyrias; Propranolol; Protoporphyrins; Rats; Rats, Inbred Strains

1991
Inactivation of rat liver microsomal steroid hydroxylations by 4-alkyl analogues of 3,5-diethoxycarbonyl-1,4-dihydro-2,4,6-trimethylpyridine: evidence for selectivity among steroid-inducible cytochrome P450IIIA forms.
    Canadian journal of physiology and pharmacology, 1990, Volume: 68, Issue:12

    Topics: Androstenedione; Animals; Cytochrome P-450 Enzyme System; Dicarbethoxydihydrocollidine; Enzyme Induction; Female; Hydroxylation; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Steroids

1990
Irreversible binding of heme to microsomal protein during inactivation of cytochrome P450 by 4-alkyl analogues of 3,5-diethoxycarbonyl-1,4-dihydro-2,4,6-trimethylpyridine.
    Biochemical pharmacology, 1990, Oct-15, Volume: 40, Issue:8

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Dexamethasone; Dicarbethoxydihydrocollidine; Enzyme Induction; Heme; Isoenzymes; Male; Microsomes, Liver; NADP; Phenobarbital; Proteins; Rats; Rats, Inbred Strains

1990
L-Alanine: 4,5-dioxovalerate transaminase does not regulate heme synthesis in rat liver.
    Biochimica et biophysica acta, 1990, May-16, Volume: 1034, Issue:2

    Topics: Alanine; Allylisopropylacetamide; Aminolevulinic Acid; Animals; Chick Embryo; Dicarbethoxydihydrocollidine; Enzyme Induction; Heme; Hemin; Liver; Male; Phenobarbital; Porphyrins; Rats; Rats, Inbred Strains; Transaminases; Valerates

1990
Effects of 4-alkyl analogues of 3,5-diethoxycarbonyl-1,4-dihydro-2,4,6-trimethylpyridine on hepatic cytochrome P-450 heme, apoproteins, and catalytic activities following in vivo administration to rats.
    Molecular pharmacology, 1990, Volume: 37, Issue:1

    Topics: Animals; Apoproteins; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Dexamethasone; Dicarbethoxydihydrocollidine; Dihydropyridines; Enzyme Induction; Heme; Immunologic Techniques; Male; Microsomes, Liver; Phenobarbital; Rats; Structure-Activity Relationship; Time Factors

1990
The cDNA and protein sequence of a phenobarbital-induced chicken cytochrome P-450.
    The Journal of biological chemistry, 1986, Jul-15, Volume: 261, Issue:20

    Topics: Allylisopropylacetamide; Amino Acid Sequence; Animals; Base Sequence; Biological Evolution; Chickens; Cytochrome P-450 Enzyme System; Dicarbethoxydihydrocollidine; DNA; DNA, Recombinant; Nucleic Acid Hybridization; Phenobarbital; Poly A; RNA; RNA, Messenger

1986
Acute hepatic heme depletion: impaired gluconeogenesis in rats.
    Seminars in hematology, 1989, Volume: 26, Issue:2

    Topics: Animals; Brain; Dicarbethoxydihydrocollidine; Gluconeogenesis; Glutathione; Glycerol; Heme; Hydroxyindoleacetic Acid; Liver; Phenobarbital; Porphyrias; Rats; Serotonin; Tryptophan; Tryptophan Oxygenase

1989
Effects of a series of 4-alkyl analogues of 3,5-diethoxycarbonyl-1,4-dihydro-2,4,6-trimethylpyridine on the major inducible cytochrome P-450 isozymes of rat liver.
    Molecular pharmacology, 1989, Volume: 35, Issue:5

    Topics: Animals; Antibodies, Monoclonal; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Dexamethasone; Dicarbethoxydihydrocollidine; Dihydropyridines; Enzyme Induction; Heme; Isoenzymes; Male; NADP; Phenobarbital; Rats; Rats, Inbred Strains

1989
Olfactory cytochrome P-450. Studies with suicide substrates of the haemoprotein.
    The Biochemical journal, 1988, Jul-15, Volume: 253, Issue:2

    Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Benzoflavones; beta-Naphthoflavone; Cricetinae; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Dicarbethoxydihydrocollidine; Epithelium; Liver; Male; Mesocricetus; NADH Dehydrogenase; Olfactory Mucosa; Oxidoreductases; Oxygenases; Peroxidases; Phenobarbital

1988
Isolation of an N-alkylprotoporphyrin IX from chick embryo livers following the administration of 3,5-diethoxycarbonyl-1,4-dihydro-4-ethyl-2,6-dimethylpyridine.
    Canadian journal of physiology and pharmacology, 1987, Volume: 65, Issue:7

    Topics: Animals; Cells, Cultured; Chick Embryo; Dicarbethoxydihydrocollidine; Dihydropyridines; Ferrochelatase; Kinetics; Liver; Lyases; Phenobarbital; Porphyrins; Protoporphyrins; Spectrophotometry

1987
Degradation of rat hepatic cytochrome P-450 heme by 3,5-dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine to irreversibly bound protein adducts.
    Archives of biochemistry and biophysics, 1987, Nov-01, Volume: 258, Issue:2

    Topics: Animals; Cytochrome P-450 Enzyme System; Dexamethasone; Dicarbethoxydihydrocollidine; Dihydropyridines; Heme; Kinetics; Male; Microsomes, Liver; Phenobarbital; Protein Binding; Rats; Rats, Inbred Strains

1987
Effect of suicide substrate on the metabolism of steroids and xenobiotics and on cytochrome P-450 apoproteins.
    Advances in experimental medicine and biology, 1986, Volume: 197

    Topics: Aminopyrine; Animals; Apoproteins; Carbon Radioisotopes; Cytochrome P-450 Enzyme System; Dicarbethoxydihydrocollidine; Formaldehyde; Formates; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Morphine; Phenobarbital; Pyridines; Rats; Rats, Inbred Strains; Testosterone

1986
N-alkylation of exogenous haem analogues caused by drugs in isolated hepatocytes. Structural isomerism and chirality of the resulting porphyrins.
    The Biochemical journal, 1986, Aug-15, Volume: 238, Issue:1

    Topics: Acetamides; Allylisopropylacetamide; Animals; Benzoflavones; beta-Naphthoflavone; Chromatography, High Pressure Liquid; Deuteroporphyrins; Dicarbethoxydihydrocollidine; In Vitro Techniques; Liver; Male; Mesoporphyrins; Phenobarbital; Porphyrins; Pyridines; Rats; Rats, Inbred Strains; Stereoisomerism

1986
The catalytic mechanism of cytochrome P-450. Spin-trapping evidence for one-electron substrate oxidation.
    The Journal of biological chemistry, 1982, Oct-10, Volume: 257, Issue:19

    Topics: Animals; Cytochrome P-450 Enzyme System; Dicarbethoxydihydrocollidine; Electron Spin Resonance Spectroscopy; Electron Transport; Male; Mass Spectrometry; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Spin Labels; Substrate Specificity

1982
Evidence that 2-allyl-2-isopropylacetamide, phenobarbital and 3,5-diethoxycarbonyl-1,4-dihydrocollidine induce the same cytochrome P450 mRNA in chick embryo liver.
    European journal of biochemistry, 1983, Nov-02, Volume: 136, Issue:2

    Topics: Acetamides; Allylisopropylacetamide; Animals; Chemical Phenomena; Chemistry; Chick Embryo; Cytochrome P-450 Enzyme System; Dicarbethoxydihydrocollidine; DNA; Enzyme Induction; Liver; Nucleic Acid Hybridization; Phenobarbital; Pyridines; RNA, Messenger

1983
N-alkylation of the haem moiety of cytochrome P-450 caused by substituted dihydropyridines. Preferential attack of different pyrrole nitrogen atoms after induction of various cytochrome P-450 isoenzymes.
    The Biochemical journal, 1983, May-01, Volume: 211, Issue:2

    Topics: Alkylation; Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Dicarbethoxydihydrocollidine; Enzyme Induction; Heme; In Vitro Techniques; Isoenzymes; Liver; Male; Phenobarbital; Protoporphyrins; Pyridines; Rats; Rats, Inbred Strains

1983
An in vitro model demonstrating the glucose effect and the influence of fasting on porphyrin metabolism.
    FEBS letters, 1982, Feb-22, Volume: 138, Issue:2

    Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Chick Embryo; Dicarbethoxydihydrocollidine; Fasting; Glucose; Phenobarbital; Porphyrins; Time Factors

1982
Evidence that in chick embryos destruction of hepatic microsomal cytochrome P-450 haem is a general mechanism of induction of delta-aminolaevulinate synthase by porphyria-causing drugs.
    The Biochemical journal, 1980, Sep-15, Volume: 190, Issue:3

    Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Chick Embryo; Cytochrome P-450 Enzyme System; Deferoxamine; Dicarbethoxydihydrocollidine; Enzyme Induction; Heme; Hemin; Microsomes, Liver; Phenobarbital; Porphyrias; Proadifen

1980
Inactivation of chick embryo hepatic cytochrome P450 1A, 2H and 3A following in ovo administration of 3,5-diethoxycarbonyl-1,4-dihydro-2,6-dimethyl-4-ethylpyridine and 3-[2-(2,4,6-trimethylphenyl)thioethyl]-4-methylsydnone.
    Biochemical pharmacology, 1995, May-17, Volume: 49, Issue:10

    Topics: Alkylation; Animals; Aryl Hydrocarbon Hydroxylases; Chick Embryo; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Dicarbethoxydihydrocollidine; Glutethimide; In Vitro Techniques; Liver; Microsomes, Liver; Oxidoreductases; Oxidoreductases, N-Demethylating; Phenobarbital; Rats; Sydnones

1995
Mechanism-based inactivation of hepatic cytochrome P450 2C6 and P450 3A1 following in vivo administration of 3,5-diethoxycarbonyl-1,4-dihydro-2,6-dimethyl-4-ethylpyridine to rats: differences from previously observed in vitro results.
    Canadian journal of physiology and pharmacology, 1994, Volume: 72, Issue:4

    Topics: Animals; Chromatography, Thin Layer; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P450 Family 2; Dexamethasone; Dicarbethoxydihydrocollidine; Female; In Vitro Techniques; Liver; Male; Microsomes, Liver; Phenobarbital; Rats; Steroid 21-Hydroxylase; Steroid Hydroxylases

1994