dicarbethoxydihydrocollidine has been researched along with 3,5-dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (40.00) | 18.7374 |
| 1990's | 12 (48.00) | 18.2507 |
| 2000's | 2 (8.00) | 29.6817 |
| 2010's | 1 (4.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alam, MT; Choudhary, MI; Kashtoh, H; Khan, A; Khan, JA; Khan, KM; Niaz, H; Perveen, S; Wahab, AT | 1 |
| Kimmett, SM; Marks, GS | 1 |
| Correia, MA; Davoll, SH; Thomas, PE; Wrighton, SA | 1 |
| Brady, AM; Lock, EA | 1 |
| Correia, MA; Rettie, AE; Waxman, DJ; Wrighton, SA; Yao, K | 1 |
| Boobis, AR; Comoglio, A; Dawson, SJ; De Matteis, F | 1 |
| Mackie, JE; Marks, GS; Massey, TE; Riddick, DS | 1 |
| Gelboin, HV; Marks, GS; Park, SS; Riddick, DS | 1 |
| Correia, MA; Lunetta, JM | 1 |
| Black, KA; Coffman, BL; Dannan, GA; Green, MD; Guengerich, FP; Tephly, TR | 2 |
| Lyon, M; Marks, GS; McCluskey, S; Powles, J; Sutherland, E; Zelt, D | 1 |
| De Matteis, F; Lock, EA; Reed, CJ | 1 |
| Marks, GS; McCluskey, SA; Racz, WJ; Sutherland, EP | 1 |
| Bornheim, L; Caldera, P; Correia, MA; Decker, C; Rettie, AE; Sugiyama, K; Trager, WF; Wrighton, SA | 1 |
| De Matteis, F; Harvey, C; Martin, SR | 1 |
| Beilan, HS; Kunze, KL; Ortiz de Montellano, PR | 1 |
| Coffman, BL; Ingall, G; Tephly, TR | 1 |
| Kimmett, SM; Marks, GS; McNamee, JP | 2 |
| Correia, MA; He, K; Licad-Coles, E; Yin, H | 1 |
| Kobus, SM; Marks, GS; McNamee, JP; Wong, SG | 1 |
| Correia, MA; Figueiredo Pereira, ME; Wang, HF | 1 |
| Correia, MA; Ren, S | 1 |
| Correia, MA; Faouzi, S; Hefner, C; Maher, JJ; Medzihradszky, KF | 1 |
25 other study(ies) available for dicarbethoxydihydrocollidine and 3,5-dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine
| Article | Year |
|---|---|
Synthesis of diethyl 4-substituted-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylates as a new series of inhibitors against yeast α-glucosidase.
Topics: alpha-Glucosidases; Animals; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carboxylic Acids; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Fibroblasts; Glycoside Hydrolase Inhibitors; Kinetics; Molecular Structure; Phosphodiesterase I; Phosphodiesterase Inhibitors; Pyridines; Rats; Saccharomyces cerevisiae; Structure-Activity Relationship | 2015 |
Thin-layer chromatographic separation of the ferrochelatase-inhibitory ring A and ring B regioisomers of N-ethylprotoporphyrin from a mixture of the four regioisomers.
Topics: Animals; Chromatography, Thin Layer; Dicarbethoxydihydrocollidine; Ferrochelatase; Isomerism; Liver; Male; Protoporphyrins; Rats; Rats, Sprague-Dawley | 1992 |
Degradation of rat liver cytochromes P450 3A after their inactivation by 3,5-dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine: characterization of the proteolytic system.
Topics: Animals; Apoenzymes; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Dicarbethoxydihydrocollidine; Isoenzymes; Kinetics; Liver; Male; Rats; Rats, Inbred Strains; Subcellular Fractions | 1992 |
Inhibition of ferrochelatase and accumulation of porphyrins in mouse hepatocyte cultures exposed to porphyrinogenic chemicals.
Topics: Aminolevulinic Acid; Animals; Cells, Cultured; Chemical and Drug Induced Liver Injury; Dicarbethoxydihydrocollidine; Ferrochelatase; Griseofulvin; Liver; Liver Diseases; Male; Mice; Porphyrias; Porphyrins | 1992 |
Differential apoprotein loss of rat liver cytochromes P450 after their inactivation by 3,5-dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine: a case for distinct proteolytic mechanisms?
Topics: Animals; Apoenzymes; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Dicarbethoxydihydrocollidine; Electrophoresis, Polyacrylamide Gel; Female; Kinetics; Male; Microsomes, Liver; Models, Structural; Molecular Weight; Rats; Rats, Inbred Strains; Trypsin | 1992 |
Inducible bilirubin-degrading system of rat liver microsomes: role of cytochrome P450IA1.
Topics: Animals; Bilirubin; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Dicarbethoxydihydrocollidine; Kidney; Male; Microsomes, Liver; Oxidoreductases; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Rats; Rats, Inbred Strains | 1991 |
3,5-Diethoxycarbonyl-2,6-dimethyl-4-ethyl-1,4-dihydropyridine inactivates rat liver cytochrome P-450c, but not its orthologue, rabbit lung form 6.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme Inhibitors; Dicarbethoxydihydrocollidine; Dihydropyridines; Heme; In Vitro Techniques; Isoenzymes; Liver; Lung; Male; Microsomes; Rabbits; Rats; Species Specificity; Triazoles | 1990 |
Effects of 4-alkyl analogues of 3,5-diethoxycarbonyl-1,4-dihydro-2,4,6-trimethylpyridine on hepatic cytochrome P-450 heme, apoproteins, and catalytic activities following in vivo administration to rats.
Topics: Animals; Apoproteins; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Dexamethasone; Dicarbethoxydihydrocollidine; Dihydropyridines; Enzyme Induction; Heme; Immunologic Techniques; Male; Microsomes, Liver; Phenobarbital; Rats; Structure-Activity Relationship; Time Factors | 1990 |
Acute hepatic heme depletion: impaired gluconeogenesis in rats.
Topics: Animals; Brain; Dicarbethoxydihydrocollidine; Gluconeogenesis; Glutathione; Glycerol; Heme; Hydroxyindoleacetic Acid; Liver; Phenobarbital; Porphyrias; Rats; Serotonin; Tryptophan; Tryptophan Oxygenase | 1989 |
Effect of the suicide substrate 3,5-diethoxycarbonyl-2,6-dimethyl-4-ethyl-1,4-dihydropyridine on the metabolism of xenobiotics and on cytochrome P-450 apoproteins.
Topics: Animals; Apoproteins; Carbon Dioxide; Carbon Radioisotopes; Cytochrome P-450 Enzyme System; Dealkylation; Dicarbethoxydihydrocollidine; Hydroxylation; In Vitro Techniques; Isoenzymes; Male; Microsomes, Liver; Pharmaceutical Preparations; Pyridines; Rats; Rats, Inbred Strains; Steroids | 1986 |
Patterns of porphyrin accumulation in response to xenobiotics. Parallels between results in chick embryo and rodents.
Topics: 5-Aminolevulinate Synthetase; Animals; Cells, Cultured; Chick Embryo; Dicarbethoxydihydrocollidine; Ferrochelatase; Liver; Polychlorinated Biphenyls; Porphyrins; Rodentia; Sydnones; Uroporphyrinogen Decarboxylase | 1987 |
Olfactory cytochrome P-450. Studies with suicide substrates of the haemoprotein.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Benzoflavones; beta-Naphthoflavone; Cricetinae; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Dicarbethoxydihydrocollidine; Epithelium; Liver; Male; Mesocricetus; NADH Dehydrogenase; Olfactory Mucosa; Oxidoreductases; Oxygenases; Peroxidases; Phenobarbital | 1988 |
Isolation of an N-alkylprotoporphyrin IX from chick embryo livers following the administration of 3,5-diethoxycarbonyl-1,4-dihydro-4-ethyl-2,6-dimethylpyridine.
Topics: Animals; Cells, Cultured; Chick Embryo; Dicarbethoxydihydrocollidine; Dihydropyridines; Ferrochelatase; Kinetics; Liver; Lyases; Phenobarbital; Porphyrins; Protoporphyrins; Spectrophotometry | 1987 |
Degradation of rat hepatic cytochrome P-450 heme by 3,5-dicarbethoxy-2,6-dimethyl-4-ethyl-1,4-dihydropyridine to irreversibly bound protein adducts.
Topics: Animals; Cytochrome P-450 Enzyme System; Dexamethasone; Dicarbethoxydihydrocollidine; Dihydropyridines; Heme; Kinetics; Male; Microsomes, Liver; Phenobarbital; Protein Binding; Rats; Rats, Inbred Strains | 1987 |
Effect of suicide substrate on the metabolism of steroids and xenobiotics and on cytochrome P-450 apoproteins.
Topics: Aminopyrine; Animals; Apoproteins; Carbon Radioisotopes; Cytochrome P-450 Enzyme System; Dicarbethoxydihydrocollidine; Formaldehyde; Formates; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Morphine; Phenobarbital; Pyridines; Rats; Rats, Inbred Strains; Testosterone | 1986 |
N-alkylation of exogenous haem analogues caused by drugs in isolated hepatocytes. Structural isomerism and chirality of the resulting porphyrins.
Topics: Acetamides; Allylisopropylacetamide; Animals; Benzoflavones; beta-Naphthoflavone; Chromatography, High Pressure Liquid; Deuteroporphyrins; Dicarbethoxydihydrocollidine; In Vitro Techniques; Liver; Male; Mesoporphyrins; Phenobarbital; Porphyrins; Pyridines; Rats; Rats, Inbred Strains; Stereoisomerism | 1986 |
N-Alkylprotoporphyrin IX formation in 3,5-dicarbethoxy-1,4-dihydrocollidine-treated rats. Transfer of the alkyl group from the substrate to the porphyrin.
Topics: Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dicarbethoxydihydrocollidine; Magnetic Resonance Spectroscopy; Male; Microsomes, Liver; Porphyrins; Protoporphyrins; Pyridines; Rats; Structure-Activity Relationship | 1981 |
The formation of N-alkylprotoporphyrin IX and destruction of cytochrome P-450 in the liver of rats after treatment with 3,5-diethoxycarbonyl-1,4-dihydrocollidine and its 4-ethyl analog.
Topics: Alkylation; Animals; Cytochrome P-450 Enzyme System; Dicarbethoxydihydrocollidine; Ferrochelatase; Male; Microsomes, Liver; Porphyrins; Protoporphyrins; Pyridines; Rats; Rats, Inbred Strains | 1982 |
Inactivation of chick embryo hepatic cytochrome P450 1A, 2H and 3A following in ovo administration of 3,5-diethoxycarbonyl-1,4-dihydro-2,6-dimethyl-4-ethylpyridine and 3-[2-(2,4,6-trimethylphenyl)thioethyl]-4-methylsydnone.
Topics: Alkylation; Animals; Aryl Hydrocarbon Hydroxylases; Chick Embryo; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Dicarbethoxydihydrocollidine; Glutethimide; In Vitro Techniques; Liver; Microsomes, Liver; Oxidoreductases; Oxidoreductases, N-Demethylating; Phenobarbital; Rats; Sydnones | 1995 |
Mechanism-based inactivation of hepatic cytochrome P450 2C6 and P450 3A1 following in vivo administration of 3,5-diethoxycarbonyl-1,4-dihydro-2,6-dimethyl-4-ethylpyridine to rats: differences from previously observed in vitro results.
Topics: Animals; Chromatography, Thin Layer; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P450 Family 2; Dexamethasone; Dicarbethoxydihydrocollidine; Female; In Vitro Techniques; Liver; Male; Microsomes, Liver; Phenobarbital; Rats; Steroid 21-Hydroxylase; Steroid Hydroxylases | 1994 |
Cytochrome P450 2C11: Escherichia coli expression, purification, functional characterization, and mechanism-based inactivation of the enzyme.
Topics: Amino Acid Sequence; Animals; Aryl Hydrocarbon Hydroxylases; Base Sequence; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Dicarbethoxydihydrocollidine; DNA, Complementary; Enzyme Inhibitors; Escherichia coli; Gene Expression; Heme; In Vitro Techniques; Male; Molecular Sequence Data; Rats; Recombinant Proteins; Sex Characteristics; Spironolactone; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases | 1997 |
Gender differences in N-alkyl protoporphyrin IX production in rats after the administration of porphyrinogenic xenobiotics.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dicarbethoxydihydrocollidine; Enzyme Activation; Female; Isoenzymes; Male; Oxidoreductases, N-Demethylating; Protoporphyrins; Rats; Rats, Sprague-Dawley; Sex Factors; Sydnones | 1998 |
Cytochrome P450 3A degradation in isolated rat hepatocytes: 26S proteasome inhibitors as probes.
Topics: Aclarubicin; Animals; Aryl Hydrocarbon Hydroxylases; Biological Transport; Brefeldin A; Cell Separation; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Cytosol; Dicarbethoxydihydrocollidine; Drug Interactions; Endoplasmic Reticulum; Female; Leupeptins; Liver; Models, Biological; Oxidoreductases, N-Demethylating; Peptide Hydrolases; Protease Inhibitors; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Ubiquitins | 1999 |
Heme: a regulator of rat hepatic tryptophan 2,3-dioxygenase?
Topics: Animals; Blotting, Western; Cytochrome P-450 Enzyme Inhibitors; Dexamethasone; Dicarbethoxydihydrocollidine; Dose-Response Relationship, Drug; Enzyme Induction; Gene Expression Regulation, Enzymologic; Heme; Hemin; Holoenzymes; Liver; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription, Genetic; Tryptophan Oxygenase | 2000 |
Characterization of the physiological turnover of native and inactivated cytochromes P450 3A in cultured rat hepatocytes: a role for the cytosolic AAA ATPase p97?
Topics: Adenine; Adenosine Triphosphatases; Ammonium Chloride; Animals; Autophagy; Boronic Acids; Cell Cycle Proteins; Cross-Linking Reagents; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dexamethasone; Dicarbethoxydihydrocollidine; Formaldehyde; Hepatocytes; Leupeptins; Lysosomes; Male; Nuclear Proteins; Polymers; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; Saccharomyces cerevisiae Proteins; Troleandomycin; Ubiquitin; Valosin Containing Protein | 2007 |