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dibenzo(a,l)pyrene and benzo(a)pyrene

dibenzo(a,l)pyrene has been researched along with benzo(a)pyrene in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (18.52)18.2507
2000's10 (37.04)29.6817
2010's11 (40.74)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Cavalieri, EL; Devanesan, PD; Higginbotham, S; RamaKrishna, NV; Rogan, EG; Salmasi, S; Todorovic, R1
Cavalieri, EL; Higginbotham, S; Johansson, SL; RamaKrishna, NV; Rogan, EG1
Il'ina, LA; Likhachev, AI; Tynbyk, ML1
Arif, JM; Gupta, RC; Smith, WA1
Adams, L; Allison, J; Davis, C; King, LC; Nelson, G; Nesnow, S; Ross, JA1
Baird, WM; Luch, A; Melendez-Colon, VJ; Seidel, A1
Binková, B; Dostál, M; Giguère, Y; Rössner, P; Srám, RJ1
Baird, WM; Keshava, C; Mahadevan, B; Musafia-Jeknic, T; Pecaj, A; Weston, A1
Baird, WM; Mahadevan, B; Musafia-Jeknic, T; Pereira, C1
Baird, WM; Bildfell, R; Courter, LA; Fischer, K; Giovanini, J; Musafia-Jeknic, T; Pereira, C1
Baird, WM; Brooks, E; Dashwood, WM; Doehmer, J; Luch, A; Mahadevan, B; Marston, CP; Pereira, C1
Högberg, J; Malmlöf, M; Pääjärvi, G; Stenius, U1
Arlt, VM; Baird, WM; Bildfell, R; Courter, LA; Fischer, K; Luch, A; Musafia-Jeknic, T; Pereira, C; Phillips, DH; Poirier, MC1
Baird, WM; Hooven, LA1
George, MH; Leavitt, SA; Moore, T; Ross, JA1
Adams, LD; DeMarini, DM; Hanley, NM; King, LC; Warren, SH1
Ahn, K; Aliaga, C; Amin, S; Bruggeman, R; Chen, KM; Cooper, T; DelTondo, J; El-Bayoumy, K; Guttenplan, JB; Jiang, K; Kosinska, W; Sharma, AK; Sun, YW; Zhang, SM; Zhao, ZL1
Filser, JG; Hutzler, C; Luch, A1
Amin, SG; Anderson, KA; Corley, RA; Crowell, SR; Krishnegowda, G; Sharma, AK; Soelberg, JJ; Williams, DE1
Arlt, VM; Baird, WM; Bradfield, CA; Krueger, SK; Larkin, A; Löhr, CV; Pereira, CB; Phillips, DH; Siddens, LK; Tilton, SC; Waters, KM; Williams, DE1
Bergvall, C; Bottai, M; Dreij, K; Jarvis, IW; Stenius, U; Westerholm, R1
Buhrke, T; Ehlers, A; Hessel, S; Lampen, A; Luckert, C; Seidel, A1
Alsberg, T; Eriksson, J; Haglund, J; Hedebrant, U; Seidel, A; Törnqvist, M; Westberg, E1
Corley, RA; Crowell, SR; Hanson-Drury, S; Williams, DE1
Akhtar, S; Arif, JM; Khan, MKA1
Chang, Y; Fischer, KA; Heine, LK; Löhr, CV; Sampson, DA; Siddens, LK; Tilton, SC; Yu, Z1
Gealy, R; Keohavong, P1

Other Studies

27 other study(ies) available for dibenzo(a,l)pyrene and benzo(a)pyrene

ArticleYear
Comparative dose-response tumorigenicity studies of dibenzo[alpha,l]pyrene versus 7,12-dimethylbenz[alpha]anthracene, benzo[alpha]pyrene and two dibenzo[alpha,l]pyrene dihydrodiols in mouse skin and rat mammary gland.
    Carcinogenesis, 1991, Volume: 12, Issue:10

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogenicity Tests; Carcinogens; Dihydroxydihydrobenzopyrenes; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Mice; Skin Neoplasms

1991
Tumor-initiating activity and carcinogenicity of dibenzo[a,l]pyrene versus 7,12-dimethylbenz[a]anthracene and benzo[a]pyrene at low doses in mouse skin.
    Carcinogenesis, 1993, Volume: 14, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Carcinoma; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred Strains; Papilloma; Sebaceous Gland Neoplasms; Skin Neoplasms; Time Factors

1993
[Specifics of interaction between benz(a)pyrene and dibenzo(a,l)pyrene with DNA of various mouse tissues].
    Voprosy onkologii, 1996, Volume: 42, Issue:5

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; DNA Adducts; Male; Mice; Mice, Hairless

1996
Tissue distribution of DNA adducts in rats treated by intramammillary injection with dibenzo[a,l]pyrene, 7,12-dimethylbenz[a]anthracene and benzo[a]pyrene.
    Mutation research, 1997, Aug-01, Volume: 378, Issue:1-2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; DNA; DNA Adducts; Female; Mammary Glands, Animal; Mutagens; Phosphorus Radioisotopes; Rats; Rats, Sprague-Dawley; Tissue Distribution; Tumor Cells, Cultured

1997
Comparison of the morphological transforming activities of dibenzo[a,l]pyrene and benzo[a]pyrene in C3H10T1/2CL8 cells and characterization of the dibenzo[a,l]pyrene-DNA adducts.
    Carcinogenesis, 1997, Volume: 18, Issue:10

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Chromatography, Thin Layer; DNA Adducts; Embryo, Mammalian; Mice

1997
Formation of stable DNA adducts and apurinic sites upon metabolic activation of bay and fjord region polycyclic aromatic hydrocarbons in human cell cultures.
    Chemical research in toxicology, 2000, Volume: 13, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apurinic Acid; Bay-Region, Polycyclic Aromatic Hydrocarbon; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Carcinogens; Cytochrome P-450 Enzyme System; DNA Adducts; DNA, Neoplasm; Dose-Response Relationship, Drug; HL-60 Cells; Humans; Peroxidases; Polycyclic Aromatic Hydrocarbons; Structure-Activity Relationship; Tumor Cells, Cultured

2000
The effect of dibenzo[a,1]pyrene and benzo[a]pyrene on human diploid lung fibroblasts: the induction of DNA adducts, expression of p53 and p21(WAF1) proteins and cell cycle distribution.
    Mutation research, 2000, Nov-20, Volume: 471, Issue:1-2

    Topics: Autoradiography; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Cycle; Cell Line; Chromatography, Affinity; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Diploidy; DNA; DNA Adducts; DNA Damage; Dose-Response Relationship, Drug; Fibroblasts; Flow Cytometry; Humans; Lung; Phosphorus Radioisotopes; Time Factors; Tumor Suppressor Protein p53

2000
Altered gene expression patterns in MCF-7 cells induced by the urban dust particulate complex mixture standard reference material 1649a.
    Cancer research, 2005, Feb-15, Volume: 65, Issue:4

    Topics: Apoptosis; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Breast Neoplasms; Carcinogens; Cell Cycle; Cell Growth Processes; Cell Line, Tumor; Cytochrome P-450 Enzyme System; DNA Adducts; DNA Damage; DNA Repair; Dust; Gene Expression; Humans; Isoenzymes

2005
Long-term effects of a standardized complex mixture of urban dust particulate on the metabolic activation of carcinogenic polycyclic aromatic hydrocarbons in human cells in culture.
    Toxicological sciences : an official journal of the Society of Toxicology, 2005, Volume: 88, Issue:2

    Topics: Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzopyrenes; Biotransformation; Breast Neoplasms; Carcinogens; Cell Line, Tumor; Complex Mixtures; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; DNA; DNA Adducts; Drug Combinations; Dust; Humans; Microsomes; Urban Health

2005
Urban dust particulate matter alters PAH-induced carcinogenesis by inhibition of CYP1A1 and CYP1B1.
    Toxicological sciences : an official journal of the Society of Toxicology, 2007, Volume: 95, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Transformation, Neoplastic; Complex Mixtures; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; DNA Adducts; DNA Damage; DNA, Neoplasm; Dust; Enzyme Induction; Enzyme Inhibitors; Mice; Mice, Inbred SENCAR; Oxazines; Particulate Matter; Polycyclic Aromatic Hydrocarbons; Risk Assessment; Skin Neoplasms; Time Factors; United States; Urban Health

2007
Competitive inhibition of carcinogen-activating CYP1A1 and CYP1B1 enzymes by a standardized complex mixture of PAH extracted from coal tar.
    International journal of cancer, 2007, Mar-15, Volume: 120, Issue:6

    Topics: Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Coal Tar; Complex Mixtures; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; DNA; DNA Adducts; Humans; Polycyclic Aromatic Hydrocarbons; Tumor Cells, Cultured

2007
Mdm2 as a sensitive and mechanistically informative marker for genotoxicity induced by benzo[a]pyrene and dibenzo[a,l]pyrene.
    Toxicological sciences : an official journal of the Society of Toxicology, 2008, Volume: 102, Issue:2

    Topics: Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Line, Tumor; Chromatin; DNA Damage; DNA, Neoplasm; Dose-Response Relationship, Drug; Genetic Markers; Humans; Mutagens; Phosphorylation; Protein Binding; Proto-Oncogene Proteins c-mdm2; RNA, Small Interfering; Transfection

2008
The influence of diesel exhaust on polycyclic aromatic hydrocarbon-induced DNA damage, gene expression, and tumor initiation in Sencar mice in vivo.
    Cancer letters, 2008, Jun-28, Volume: 265, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Cell Transformation, Neoplastic; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; DNA Adducts; DNA Damage; Mice; Mice, Inbred SENCAR; Particulate Matter; Polycyclic Aromatic Hydrocarbons; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vehicle Emissions

2008
Proteomic analysis of MCF-7 cells treated with benzo[a]pyrene, dibenzo[a,l]pyrene, coal tar extract, and diesel exhaust extract.
    Toxicology, 2008, Jul-10, Volume: 249, Issue:1

    Topics: Benzo(a)pyrene; Benzopyrenes; Breast Neoplasms; Carcinogens; Cell Line, Tumor; Coal Tar; Electrophoresis, Polyacrylamide Gel; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Proteome; Proteomics; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Vehicle Emissions

2008
Mutations induced by benzo[a]pyrene and dibenzo[a,l]pyrene in lacI transgenic B6C3F1 mouse lung result from stable DNA adducts.
    Mutagenesis, 2008, Volume: 23, Issue:6

    Topics: Animals; Bacterial Proteins; Benzo(a)pyrene; Benzopyrenes; Carcinogens; DNA Adducts; DNA Damage; Female; Lac Repressors; Lung; Male; Mice; Mice, Transgenic; Mutation; Repressor Proteins

2008
Association between mutation spectra and stable and unstable DNA adduct profiles in Salmonella for benzo[a]pyrene and dibenzo[a,l]pyrene.
    Mutation research, 2011, Sep-01, Volume: 714, Issue:1-2

    Topics: Adenine; Benzo(a)pyrene; Benzopyrenes; DNA Adducts; Guanine; Mutagenicity Tests; Mutagens; Mutation; Salmonella

2011
Mutagenesis and carcinogenesis induced by dibenzo[a,l]pyrene in the mouse oral cavity: a potential new model for oral cancer.
    International journal of cancer, 2012, Jun-15, Volume: 130, Issue:12

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogenicity Tests; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cyclooxygenase 2; Disease Models, Animal; Female; Mice; Mouth; Mouth Neoplasms; Mutagenesis; Tumor Suppressor Protein p53

2012
Analysis of carcinogenic polycyclic aromatic hydrocarbons in complex environmental mixtures by LC-APPI-MS/MS.
    Analytica chimica acta, 2011, Sep-30, Volume: 702, Issue:2

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens; Chromatography, Liquid; Chrysenes; Environmental Pollutants; Gas Chromatography-Mass Spectrometry; Humans; Polycyclic Aromatic Hydrocarbons; Sensitivity and Specificity

2011
Preliminary physiologically based pharmacokinetic models for benzo[a]pyrene and dibenzo[def,p]chrysene in rodents.
    Toxicology and applied pharmacology, 2011, Dec-15, Volume: 257, Issue:3

    Topics: Administration, Oral; Algorithms; Animals; Benzo(a)pyrene; Benzopyrenes; Environmental Pollutants; Female; Injections, Intravenous; Mice; Models, Biological; Rats; Rats, Sprague-Dawley; Tissue Distribution

2011
Polycyclic aromatic hydrocarbons as skin carcinogens: comparison of benzo[a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse.
    Toxicology and applied pharmacology, 2012, Nov-01, Volume: 264, Issue:3

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Carcinogens, Environmental; Gene Expression Regulation, Neoplastic; Mice; Mice, Inbred Strains; Molecular Structure; Principal Component Analysis; Protein Array Analysis; Skin Neoplasms; Transcriptome

2012
Persistent activation of DNA damage signaling in response to complex mixtures of PAHs in air particulate matter.
    Toxicology and applied pharmacology, 2013, Feb-01, Volume: 266, Issue:3

    Topics: Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzopyrenes; Blotting, Western; Cell Survival; Checkpoint Kinase 1; Comet Assay; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; DNA Damage; Hep G2 Cells; Humans; Linear Models; Liver; Particulate Matter; Protein Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA; Signal Transduction; Urban Population

2013
Polycyclic aromatic hydrocarbons stimulate human CYP3A4 promoter activity via PXR.
    Toxicology letters, 2013, Oct-24, Volume: 222, Issue:2

    Topics: Benzo(a)pyrene; Benzopyrenes; Carcinogens, Environmental; Cell Survival; Cytochrome P-450 CYP3A; Dihydroxydihydrobenzopyrenes; Enzyme Induction; Epoxy Compounds; Genes, Reporter; HEK293 Cells; Hep G2 Cells; Humans; Inhibitory Concentration 50; Ligands; Polycyclic Aromatic Hydrocarbons; Pregnane X Receptor; Promoter Regions, Genetic; Receptors, Steroid; Recombinant Proteins; Signal Transduction; Transcriptional Activation

2013
Conditions for sample preparation and quantitative HPLC/MS-MS analysis of bulky adducts to serum albumin with diolepoxides of polycyclic aromatic hydrocarbons as models.
    Analytical and bioanalytical chemistry, 2014, Volume: 406, Issue:5

    Topics: Benz(a)Anthracenes; Benzo(a)pyrene; Benzopyrenes; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Hydrolysis; Peptide Fragments; Pronase; Reproducibility of Results; Serum Albumin; Tandem Mass Spectrometry

2014
In vitro metabolism of benzo[a]pyrene and dibenzo[def,p]chrysene in rodent and human hepatic microsomes.
    Toxicology letters, 2014, Jul-03, Volume: 228, Issue:1

    Topics: Algorithms; Animals; Benzo(a)pyrene; Benzopyrenes; Body Weight; Carcinogens; Data Interpretation, Statistical; Female; Half-Life; Humans; Kinetics; Male; Mice; Microsomes, Liver; Organ Size; Polycyclic Aromatic Hydrocarbons; Pregnancy; Rats; Rats, Sprague-Dawley

2014
Structural Insight into the Mechanism of Dibenzo[a,l]pyrene and Benzo[a]pyrene-Mediated Cell Proliferation Using Molecular Docking Simulations.
    Interdisciplinary sciences, computational life sciences, 2018, Volume: 10, Issue:4

    Topics: Benzo(a)pyrene; Benzopyrenes; Biomarkers; Cell Proliferation; Molecular Docking Simulation; Reproducibility of Results

2018
Comparative mechanisms of PAH toxicity by benzo[a]pyrene and dibenzo[def,p]chrysene in primary human bronchial epithelial cells cultured at air-liquid interface.
    Toxicology and applied pharmacology, 2019, 09-15, Volume: 379

    Topics: Benzo(a)pyrene; Benzopyrenes; Bronchi; Cells, Cultured; Dose-Response Relationship, Drug; Gene Expression; Humans; Kruppel-Like Factor 4; L-Lactate Dehydrogenase; Polycyclic Aromatic Hydrocarbons; Respiratory Mucosa; Sequence Analysis, RNA; Toxicity Tests; Transcriptome

2019
Determination of Mutational Spectra Induced by Environmental Toxicants in Complex Human Cell Populations.
    Methods in molecular biology (Clifton, N.J.), 2020, Volume: 2102

    Topics: Benzo(a)pyrene; Benzopyrenes; Cell Line; Cytochrome P-450 Enzyme Inducers; Denaturing Gradient Gel Electrophoresis; Electrophoresis, Polyacrylamide Gel; Exons; Guanosine; Humans; Hypoxanthine Phosphoribosyltransferase; Mutagenesis; Mutagens; Mutation; Polymerase Chain Reaction; Thionucleosides; Workflow

2020