diazoxide has been researched along with wortmannin in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 5 (45.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Ashford, ML; Harvey, J | 1 |
| Benoit, JN; Cohen, MV; Downey, JM; Oldenburg, O; Qin, Q; Sharma, AR | 1 |
| Ahmad, N; Ashraf, M; Haider, KH; Pasha, Z; Uzun, O; Wang, B; Wang, Y | 1 |
| Dreixler, JC; Hemmert, JW; Lee, HT; Rosenbaum, DM; Roth, S; Shaikh, AR; Shen, Y; Shenoy, SK | 1 |
| Afzal, MR; Ahmed, RP; Ashraf, M; Haider, HKh; Idris, NM; Jiang, S | 1 |
| Carnická, S; Kolár, F; Matejíková, J; Pancza, D; Ravingerová, T | 1 |
| Abe, E; Abe, T; Fujiki, M; Ishii, K; Kobayashi, H; Kubo, T; Nagai, Y; Shiqi, K | 1 |
| Cao, L; Chi, Z; Jiang, H; Xie, N; Xue, Y; Zhao, X | 1 |
11 other study(ies) available for diazoxide and wortmannin
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Insulin occludes leptin activation of ATP-sensitive K+ channels in rat CRI-G1 insulin secreting cells.
Topics: Adenosine Triphosphate; Androstadienes; Animals; Binding, Competitive; Chromones; Diabetes Mellitus, Type 2; Diazoxide; Drug Interactions; Electric Conductivity; Enzyme Inhibitors; Hypoglycemic Agents; Insulin; Insulin Antagonists; Insulin Secretion; Insulin-Like Growth Factor I; Ion Channel Gating; Leptin; Membrane Potentials; Morpholines; Patch-Clamp Techniques; Potassium Channels; Proteins; Rats; Tolbutamide; Vasodilator Agents; Wortmannin | 1998 |
Acetylcholine leads to free radical production dependent on K(ATP) channels, G(i) proteins, phosphatidylinositol 3-kinase and tyrosine kinase.
Topics: Acetylcholine; Analysis of Variance; Androstadienes; Animals; Aorta; Atropine; Cell Line; Decanoic Acids; Diazoxide; Enzyme Inhibitors; Female; Free Radical Scavengers; Genistein; GTP-Binding Protein alpha Subunits, Gi-Go; Hydroxy Acids; Ionophores; Ischemic Preconditioning; Male; Methacholine Chloride; Microscopy, Fluorescence; Muscarinic Agonists; Muscle, Smooth, Vascular; Perfusion; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Piperidines; Potassium Channel Blockers; Potassium Channels; Protein-Tyrosine Kinases; Rabbits; Rats; Reactive Oxygen Species; Receptors, Cholinergic; Signal Transduction; Tiopronin; Valinomycin; Wortmannin | 2002 |
Cardiac protection by mitoKATP channels is dependent on Akt translocation from cytosol to mitochondria during late preconditioning.
Topics: Androstadienes; Animals; Apoptosis; Benzopyrans; Blotting, Western; Cardiotonic Agents; Cytosol; Diazoxide; Enzyme Inhibitors; Hemodynamics; Imidazoles; In Situ Nick-End Labeling; In Vitro Techniques; Ischemic Preconditioning, Myocardial; L-Lactate Dehydrogenase; Male; Mice; Mice, Inbred C57BL; Mitochondria, Heart; Myocardial Ischemia; Phosphorylation; Potassium Channels; Proto-Oncogene Proteins c-akt; Translocation, Genetic; Vasodilator Agents; Wortmannin | 2006 |
The role of Akt/protein kinase B subtypes in retinal ischemic preconditioning.
Topics: Androstadienes; Animals; Apoptosis; Blotting, Western; Chlorpropamide; Diazoxide; Dose-Response Relationship, Drug; Electroretinography; Ischemia; Ischemic Preconditioning; Isoenzymes; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Retinal Vessels; RNA, Small Interfering; Wortmannin | 2009 |
Preconditioning promotes survival and angiomyogenic potential of mesenchymal stem cells in the infarcted heart via NF-kappaB signaling.
Topics: Androstadienes; Animals; Cell Survival; Diazoxide; Disease Models, Animal; Echocardiography; Female; Gene Silencing; Hydrogen Peroxide; Ischemic Preconditioning, Myocardial; Male; Mesenchymal Stem Cells; Myocardial Infarction; Neovascularization, Physiologic; NF-kappa B; Oxidative Stress; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Wortmannin | 2010 |
Mitochondrial KATP opening confers protection against lethal myocardial injury and ischaemia-induced arrhythmias in the rat heart via PI3K/Akt-dependent and -independent mechanisms.
Topics: Androstadienes; Animals; Arrhythmias, Cardiac; Diazoxide; Mitochondria, Heart; Myocardial Ischemia; Myocardial Reperfusion Injury; Phosphatidylinositol 3-Kinases; Potassium Channels; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Vasodilator Agents; Wortmannin | 2009 |
The phosphatidylinositol-3 kinase/Akt pathway mediates geranylgeranylacetone-induced neuroprotection against cerebral infarction in rats.
Topics: Androstadienes; Animals; Brain; Brain Infarction; Central Nervous System Agents; Decanoic Acids; Diazoxide; Diterpenes; Enzyme Inhibitors; Hydroxy Acids; Infarction, Middle Cerebral Artery; KATP Channels; Male; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Signal Transduction; Time Factors; Wortmannin | 2010 |
Diazoxide preconditioning against seizure-induced oxidative injury is via the PI3K/Akt pathway in epileptic rat.
Topics: Androstadienes; Animals; Decanoic Acids; Diazoxide; Epilepsy; Hydroxy Acids; Male; Malondialdehyde; Neuroprotective Agents; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pilocarpine; Potassium Channel Blockers; Potassium Channels; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Seizures; Signal Transduction; Superoxide Dismutase; Wortmannin | 2011 |