diazoxide has been researched along with verapamil in 54 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (33.33) | 18.7374 |
| 1990's | 13 (24.07) | 18.2507 |
| 2000's | 10 (18.52) | 29.6817 |
| 2010's | 13 (24.07) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Boverie, S; de Tullio, P; Florence, X; Goffin, E; Lebrun, P; Pirotte, B; Somers, F | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| de Tullio, P; Desvaux, V; Florence, X; Goffin, E; Lebrun, P; Pirotte, B | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Bouhedja, M; Boumendjel, A; Faury, G; Fhayli, W; Ghandour, Z; Khelili, S; Peres, B | 1 |
| Bristow, MR; Green, RD | 1 |
| Diamond, J; Janis, RA | 1 |
| Mikhailov, AA; Sivkova, SK; Sumarokov, AV; Tatsievskiĭ, VA | 1 |
| Denkl, P; Haas, Th | 1 |
| Levy, JV | 1 |
| Briggs, JP; Brosius, FC; Furspan, PB; Lorenz, JN; Schnermann, J | 1 |
| Littler, WA; Smith, SA | 1 |
| Clark, AG; Hardcastle, JD; Stower, MJ; Wright, JW | 1 |
| Nast, HP; Philipp, T | 1 |
| Both, A | 1 |
| Charles, S; Henquin, JC; Mathot, F; Nenquin, M; Tamagawa, T | 1 |
| Anand, MP | 1 |
| Albrecht, T; Speelman, DJ; Steinsland, OS | 1 |
| Chapman, RW; Danko, G; Siegel, MI | 1 |
| Brandt, D | 1 |
| Zsotér, TT | 1 |
| Leinweber, KP; Schatz, H | 1 |
| Bender, F | 1 |
| Cook, DI; Poronnik, P; Tuch, BE; Weinhaus, AJ | 2 |
| Elias, PM; Feingold, KR; Lee, SH; Mauro, T | 1 |
| Kojima, I; Mine, T; Sekine, N; Shibata, H; Totsuka, Y; Yasuda, H | 1 |
| Djurhuus, JC; Kirkeby, HJ; Lundbech, PE | 1 |
| Iguchi, A; Maeda, N; Miura, H; Niki, I; Nonogaki, K; Ozawa, K; Tamagawa, T; Uemura, K; Watanabe, G | 1 |
| Gäbel, J; Lebrun, P; Malaisse, WJ; Pirotte, B; Rorsman, P; Valverde, I; Van Poelje, PD; Villanueva-Peñacarrillo, ML; Viñambres, C | 1 |
| Li, G; Pralong, WF; Wollheim, CB | 1 |
| Barnett, CR; Flatt, PR; McClenaghan, NH; O'Harte, FP | 1 |
| Carvajal, A; Dueñas, A; Fernández de la Gándara, F; Maroto, M; Nieto, A; Velasco, A | 1 |
| Jijakli, H; Malaisse, WJ | 1 |
| Ashraf, M; Wang, Y | 1 |
| Flatt, PR; McClenaghan, NH | 1 |
| De Proft, R; Dejonghe, S; Gorus, F; Ling, Z; Pipeleers, D; Schuit, F; Winnock, F | 1 |
| Chan, CB; Joseph, JW; MacDonald, PE; Sakellaropoulos, G; Salapatek, AM; Saleh, MC; Sewing, S; Smukler, SR; Tsushima, RG; Wang, J; Wheeler, MB | 1 |
| Bruce, IC; Chen, YY; Shen, YL; Wu, XD; Xia, Q | 1 |
| Abdel-Wahab, YH; Ali, L; Flatt, PR; Hannan, JM; Marenah, L; Rokeya, B | 1 |
| Kaku, K; Katsura, M; Matsuda, M; Ohkuma, S; Shigeto, M | 1 |
| Abdel-Wahab, YH; Conlon, JM; Flatt, PR; Power, GJ; Rollins-Smith, LA; Woodhams, DC | 1 |
| Abdel-Wahab, YH; Flatt, PR; Kasabri, V | 1 |
| Kamalinejad, M; Keshavarz, M; Mirghazanfari, SM; Nabavizadeh, F; Soltani, N | 1 |
4 review(s) available for diazoxide and verapamil
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Antihypertensive agents--the race for third place.
Topics: Adrenergic alpha-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Captopril; Diazoxide; Felodipine; Humans; Hydralazine; Indoramin; Labetalol; Minoxidil; Nicardipine; Nifedipine; Vasodilator Agents; Verapamil | 1985 |
Hypertension--drug management.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Calcium Channel Blockers; Captopril; Diazoxide; Humans; Hypertension; Indoramin; Labetalol; Minoxidil; Nifedipine; Nitroprusside; Prazosin; Sympatholytics; Vasodilator Agents; Verapamil | 1982 |
Calcium antagonists.
Topics: Action Potentials; Angina Pectoris; Angina Pectoris, Variant; Arrhythmias, Cardiac; Bronchial Spasm; Calcium; Diazoxide; Diltiazem; Hemodynamics; Humans; Hydralazine; Lanthanum; Muscle, Smooth; Myocardial Contraction; Nifedipine; Nitrites; Nitroprusside; Papillary Muscles; Verapamil | 1980 |
50 other study(ies) available for diazoxide and verapamil
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
1,4,2-Benzo/pyridodithiazine 1,1-dioxides structurally related to the ATP-sensitive potassium channel openers 1,2,4-Benzo/pyridothiadiazine 1,1-dioxides exert a myorelaxant activity linked to a distinct mechanism of action.
Topics: Animals; Benzothiadiazines; Diazoxide; Insulin-Secreting Cells; KATP Channels; Muscle Relaxation; Muscle, Smooth, Vascular; Parasympatholytics; Structure-Activity Relationship; Thiadiazines | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Influence of the alkylsulfonylamino substituent located at the 6-position of 2,2-dimethylchromans structurally related to cromakalim: from potassium channel openers to calcium entry blockers?
Topics: Animals; Aorta; Biological Transport; Calcium; Chromans; Cromakalim; Dose-Response Relationship, Drug; Insulin; Insulin Secretion; Insulin-Secreting Cells; Ion Channel Gating; Muscle Contraction; Potassium Channels; Potassium Chloride; Rats; Stereoisomerism; Structure-Activity Relationship; Sulfur Compounds | 2014 |
Design, synthesis and biological evaluation of novel ring-opened cromakalim analogues with relaxant effects on vascular and respiratory smooth muscles and as stimulators of elastin synthesis.
Topics: Animals; Cromakalim; Dose-Response Relationship, Drug; Drug Design; Elastin; Female; Molecular Structure; Muscle Contraction; Muscle, Smooth; Rats; Rats, Wistar; Structure-Activity Relationship | 2018 |
Effect of diazoxide, verapamil and compound D600 on isoproterenol and calcium-mediated dose-response relationships in isolated rabbit atrium.
Topics: Adrenergic beta-Antagonists; Animals; Calcium; Diazoxide; Dose-Response Relationship, Drug; Drug Interactions; Female; Gallopamil; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Rabbits; Verapamil | 1977 |
Relationship between cyclic nucleotide levels and drug-induced relaxation of smooth muscle.
Topics: Animals; Cyclic AMP; Cyclic GMP; Diazoxide; Drug Interactions; Female; Guinea Pigs; Hydralazine; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitroprusside; Verapamil | 1979 |
[Treatment of severe hypertensive conditions].
Topics: Adolescent; Adult; Diazoxide; Drug Therapy, Combination; Female; Humans; Hypertension; Infusions, Parenteral; Male; Middle Aged; Nitroprusside; Verapamil | 1979 |
[Therapy of hypertensive crises].
Topics: Acute Disease; Adrenal Gland Neoplasms; Antihypertensive Agents; Clonidine; Diazoxide; Dihydralazine; Guanethidine; Humans; Hypertension; Hypertension, Malignant; Hypertension, Renal; Methyldopa; Nitroprusside; Pheochromocytoma; Reserpine; Verapamil | 1977 |
Verapamil and diazoxide antagonism of agonist-induced contractions of aortic strips from normal and spontaneously hypertensive rats (SHR).
Topics: Animals; Aorta, Thoracic; Diazoxide; Hypertension; In Vitro Techniques; Methoxamine; Muscle Contraction; Muscle, Smooth; Potassium Chloride; Prostaglandins E; Rats; Verapamil | 1975 |
Intracellular ATP can regulate afferent arteriolar tone via ATP-sensitive K+ channels in the rabbit.
Topics: Adenosine Triphosphate; Animals; Arterioles; Deoxyglucose; Diazoxide; Glyburide; In Vitro Techniques; Perfusion; Potassium Channels; Rabbits; Vasoconstriction; Verapamil | 1992 |
The effect of various drugs on canine ureteric peristalsis.
Topics: Animals; Colic; Diazoxide; Dogs; Drug Evaluation, Preclinical; Female; Muscle Contraction; Ritodrine; Terbutaline; Ureter; Ureteral Diseases; Verapamil | 1986 |
[Hypertensive emergencies].
Topics: Brain Edema; Clonidine; Diazoxide; Digitalis Glycosides; Diuretics; Drug Combinations; Emergencies; Ferricyanides; Ganglionic Blockers; Guanethidine; Humans; Hydralazine; Hypertension; Hypertension, Malignant; Hypnotics and Sedatives; Intensive Care Units; Methyldopa; Minoxidil; Nitric Oxide; Pheochromocytoma; Reserpine; Verapamil | 1974 |
[Therapy of primary pulmonary hypertension].
Topics: Acetylcholine; Amino Alcohols; Carbachol; Child; Diazepam; Diazoxide; Female; Humans; Hypertension, Pulmonary; Isoproterenol; Isosorbide Dinitrate; Neostigmine; Nitroglycerin; Pentaerythritol Tetranitrate; Rest; Theophylline; Tolazoline; Verapamil | 1970 |
Diazoxide and D600 inhibition of insulin release. Distinct mechanisms explain the specificity for different stimuli.
Topics: Adrenergic alpha-Antagonists; Animals; Arginine; Calcium; Depression, Chemical; Diazoxide; Epinephrine; Gallopamil; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Lysine; Male; Rats; Rats, Inbred Strains; Theophylline; Verapamil | 1982 |
Similarities between cytomegalovirus-induced cell rounding and contraction of smooth muscle cells.
Topics: Cytomegalovirus; Cytomegalovirus Infections; Cytopathogenic Effect, Viral; Diazoxide; Fibroblasts; Humans; Hydralazine; Muscle Contraction; Muscle, Smooth; Nitroprusside; Papaverine; Verapamil | 1983 |
Effect of extra- and intracellular calcium blockers on histamine and antigen-induced bronchospasms in guinea pigs and rats.
Topics: Albuterol; Animals; Bronchial Spasm; Calcium Channel Blockers; Diazoxide; Gallic Acid; Guinea Pigs; Hemodynamics; Histamine; Immunization; Male; Nifedipine; Ovalbumin; Rats; Species Specificity; Verapamil | 1984 |
[The hypertensive crisis].
Topics: Acute Disease; Calcium Channel Blockers; Clonidine; Coronary Disease; Diazoxide; Dihydralazine; Diltiazem; Heart Failure; Humans; Hypertension; Nifedipine; Nitroprusside; Sympatholytics; Verapamil | 1984 |
Long-term and short-term effects of calcium, verapamil and diazoxide on biosynthesis and release of (pro-) insulin in isolated islets of rat pancreas.
Topics: Animals; Calcium; Cells, Cultured; Diazoxide; Insulin; Islets of Langerhans; Leucine; Male; Proinsulin; Rats; Time Factors; Verapamil | 1982 |
Acute hypertensive crises.
Topics: Acute Disease; Adult; Aged; Clonidine; Diazoxide; Heart Block; Humans; Hypertension; Injections, Intravenous; Myocardial Infarction; Nitroprusside; Reserpine; Verapamil | 1980 |
Insulin secretagogues, but not glucose, stimulate an increase in [Ca2+]i in the fetal rat beta-cell.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arginine; Calcium; Cells, Cultured; Diazoxide; Female; Fetus; Glipizide; Glucose; Glyceraldehyde; Immunohistochemistry; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Pancreas; Rats; Rats, Wistar; Verapamil | 1995 |
A role for ions in barrier recovery after acute perturbation.
Topics: Animals; Calcium; Calcium Channels; Calmodulin; Cell Membrane Permeability; Diazoxide; Dihydropyridines; Homeostasis; Ions; Mice; Mice, Hairless; Minoxidil; Ouabain; Permeability; Potassium; Potassium Channels; Skin; Skin Physiological Phenomena; Sodium-Potassium-Exchanging ATPase; Verapamil; Water-Electrolyte Balance | 1994 |
Activin A increases intracellular free calcium concentrations in rat pancreatic islets.
Topics: Activins; Animals; Calcium; Carbachol; Cyclic AMP; Diazoxide; Inhibins; Insulin; Insulin Secretion; Islets of Langerhans; Male; Nifedipine; Nitrendipine; Rats; Rats, Wistar; Verapamil | 1993 |
A hydrodynamic model of rabbit corpus cavernosum pressure responses to vasodilators.
Topics: Animals; Blood Pressure; Diazoxide; Male; Models, Biological; Nitroglycerin; Penis; Rabbits; Vascular Resistance; Vasodilator Agents; Verapamil | 1993 |
Increase in insulin release from rat pancreatic islets by quinolone antibiotics.
Topics: 4-Quinolones; Adenosine Triphosphate; Animals; Anti-Infective Agents; Calcium Channel Blockers; Cyclic AMP; Diazoxide; Diuretics; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Potassium Channels; Rats; Rats, Wistar; Sodium Chloride Symporter Inhibitors; Stimulation, Chemical; Verapamil | 1996 |
The riddle of formycin A insulinotropic action.
Topics: Adenosine; Animals; Calcium; Diabetes Mellitus, Type 2; Diazoxide; Female; Formycins; Glucose; Glyburide; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Rats; Ribonucleotides; Tubercidin; Verapamil; Xanthines | 1996 |
Oscillations of cytosolic free calcium in bombesin-stimulated HIT-T15 cells.
Topics: Animals; Biological Clocks; Bombesin; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium-Transporting ATPases; Cell Line; Central Nervous System Stimulants; Chelating Agents; Circadian Rhythm; Cresols; Cricetinae; Cytosol; Diazoxide; Egtazic Acid; Fura-2; Glucose; Hydroquinones; Membrane Potentials; Ryanodine; Verapamil | 1996 |
Mechanisms of amino acid-induced insulin secretion from the glucose-responsive BRIN-BD11 pancreatic B-cell line.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Arginine; Calcium Channel Blockers; Cell Line; Diazoxide; Dose-Response Relationship, Drug; Glucose; Glutamine; Glyceraldehyde; Glycine; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Lysine; Potassium Channels; Proline; Radioimmunoassay; Rats; Serine; Stimulation, Chemical; Verapamil | 1996 |
Mechanisms of arginine-induced increase in cytosolic calcium concentration in the beta-cell line NIT-1.
Topics: Animals; Arginine; Calcium; Cell Line; Cytosol; Diazoxide; Homoarginine; Insulin; Insulin Secretion; Insulinoma; Kinetics; Mice; Mice, Transgenic; Molsidomine; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Pancreatic Neoplasms; Potassium Channels; Potassium Chloride; Tumor Cells, Cultured; Verapamil | 1997 |
Effect of 4-aminopyridine and 3,4-diaminopyridine on guinea-pig isolated ileum.
Topics: 4-Aminopyridine; Acetylcholine; Amifampridine; Animals; Atropine; Calcium Channel Blockers; Diazoxide; Diltiazem; Dose-Response Relationship, Drug; Drug Interactions; Female; Flunarizine; Guinea Pigs; Ileum; In Vitro Techniques; Lanthanum; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Parasympathetic Nervous System; Parasympatholytics; Potassium Channels; Vasodilator Agents; Verapamil | 1997 |
Verapamil- and cadmium-resistant stimulation of calcium uptake and insulin release by D-glucose in depolarised pancreatic islets exposed to diazoxide.
Topics: Animals; Cadmium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Diazoxide; Female; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Membrane Potentials; Perfusion; Rats; Rats, Wistar; Verapamil | 1998 |
Role of protein kinase C in mitochondrial KATP channel-mediated protection against Ca2+ overload injury in rat myocardium.
Topics: Adenosine Triphosphate; Alkaloids; Animals; Benzophenanthridines; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Coronary Circulation; Diazoxide; Enzyme Activation; Enzyme Inhibitors; Immunohistochemistry; Ischemic Preconditioning; Isoenzymes; L-Lactate Dehydrogenase; Male; Mitochondria; Myocardial Ischemia; Myocardium; Nifedipine; Phenanthridines; Potassium Channels; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Protein Kinase C-delta; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; Vasodilator Agents; Verapamil | 1999 |
Metabolic and K(ATP) channel-independent actions of keto acid initiators of insulin secretion.
Topics: Animals; Arginine; Butyrates; Calcium; Calcium Channel Blockers; Calcium Channels; Coumaric Acids; Diazoxide; Glucose; Insulin; Insulin Secretion; Insulinoma; Ion Channel Gating; Ion Transport; Islets of Langerhans; Isoleucine; Keto Acids; Leucine; Membrane Potentials; Membrane Proteins; Mitochondria; Pancreatic Neoplasms; Phenylpyruvic Acids; Potassium Channels; Secretory Rate; Sodium Azide; Sodium Cyanide; Tumor Cells, Cultured; Valine; Verapamil | 2000 |
Correlation between GABA release from rat islet beta-cells and their metabolic state.
Topics: 1-Methyl-3-isobutylxanthine; 2,4-Dinitrophenol; Adenosine Triphosphate; Animals; Calcium; Culture Media, Conditioned; Cycloheximide; Diazoxide; gamma-Aminobutyric Acid; Glucagon; Glucagon-Like Peptide 1; Glucose; Glutamate Decarboxylase; Glyburide; Islets of Langerhans; Male; Mannoheptulose; Oxidation-Reduction; Peptide Fragments; Protein Precursors; Rats; Rats, Wistar; Verapamil | 2002 |
Inhibition of Kv2.1 voltage-dependent K+ channels in pancreatic beta-cells enhances glucose-dependent insulin secretion.
Topics: Animals; Calcium; Calcium Channel Blockers; Delayed Rectifier Potassium Channels; Diazoxide; Female; Glucose; Humans; In Vitro Techniques; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Membrane Potentials; Mice; Pancreas; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Recombinant Fusion Proteins; Shab Potassium Channels; Tetraethylammonium; Tumor Cells, Cultured; Verapamil | 2002 |
Activation of mitochondrial ATP-sensitive potassium channels delays ischemia-induced cellular uncoupling in rat heart.
Topics: Adenosine Triphosphate; Animals; Decanoic Acids; Diazoxide; Hydroxy Acids; Ion Channel Gating; Ischemic Preconditioning, Myocardial; Male; Mitochondria, Heart; Myocardial Reperfusion Injury; Potassium Channels; Rats; Rats, Sprague-Dawley; Verapamil | 2004 |
Ocimum sanctum leaf extracts stimulate insulin secretion from perfused pancreas, isolated islets and clonal pancreatic beta-cells.
Topics: 1-Methyl-3-isobutylxanthine; Acetates; Animals; Butanols; Cell Line; Diazoxide; Ethanol; Glucose; Insulin; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Ocimum; Pancreas; Perfusion; Plant Extracts; Plant Leaves; Potassium Chloride; Rats; Rats, Long-Evans; Tissue Culture Techniques; Tolbutamide; Verapamil | 2006 |
First phase of glucose-stimulated insulin secretion from MIN 6 cells does not always require extracellular calcium influx.
Topics: Animals; Calcium; Calcium Isotopes; Cell Line, Tumor; Cell Survival; Dantrolene; Diazoxide; Dose-Response Relationship, Drug; Extracellular Fluid; Glucose; Glyburide; Insulin; Insulin Antagonists; Insulin Secretion; Insulin-Secreting Cells; L-Lactate Dehydrogenase; Male; Mice; Potassium Channels; Sodium Channels; Tetrodotoxin; Tolbutamide; Verapamil | 2006 |
A peptide of the phylloseptin family from the skin of the frog Hylomantis lemur (Phyllomedusinae) with potent in vitro and in vivo insulin-releasing activity.
Topics: Amino Acid Sequence; Animals; Antimicrobial Cationic Peptides; Anura; Calcium; Cell Line; Diazoxide; Exocytosis; Extracellular Fluid; Glucose; Hydro-Lyases; Insulin; Insulin Secretion; Mice; Molecular Sequence Data; Rats; Skin; Verapamil | 2008 |
Terminalia bellirica stimulates the secretion and action of insulin and inhibits starch digestion and protein glycation in vitro.
Topics: Animals; Calcium; Cell Line; Diazoxide; Digestion; Fruit; Insulin; Insulin Secretion; Islets of Langerhans; Plant Extracts; Rats; Starch; Terminalia; Verapamil | 2010 |
The effect of "Teucrium polium L." extracts on insulin release from in situ isolated perfused rat pancreas in a newly modified isolation method: the role of Ca2+ and K+ channels.
Topics: Animals; Apigenin; Calcium Channel Blockers; Calcium Channels; Diazoxide; Gas Chromatography-Mass Spectrometry; Glucose; Hypoglycemic Agents; Insulin; Insulin Secretion; Male; Pancreas; Perfusion; Plant Extracts; Potassium Channels; Rats; Teucrium; Time Factors; Verapamil | 2010 |