diazoxide has been researched along with valinomycin in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 7 (58.33) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Holmuhamedov, EL; Terzic, A; Wang, L | 1 |
| Debska, G; Elger, CE; Kicińska, A; Kunz, WS; May, R; Szewczyk, A | 1 |
| Benoit, JN; Cohen, MV; Downey, JM; Oldenburg, O; Qin, Q; Sharma, AR | 1 |
| Alexeyev, MF; Cohen, MV; Downey, JM; Felix, SB; Krieg, T; Landsberger, M | 1 |
| Boengler, K; Buechert, A; Di Lisa, F; García-Dorado, D; Heinzel, FR; Heusch, G; Li, X; Luo, Y; Schulz, R | 1 |
| Andrukhiv, A; Costa, AD; Garlid, KD; Jabůrek, M; Quinlan, CL; West, IC | 1 |
| Andrukhiv, A; Costa, AD; Garlid, KD; West, IC | 1 |
| Kukreja, RC | 1 |
| Elmér, E; Hansson, MJ; Mattiasson, G; Morota, S; Teilum, M; Uchino, H | 1 |
| Hansson, MJ; Morota, S; Piel, S | 1 |
12 other study(ies) available for diazoxide and valinomycin
| Article | Year |
|---|---|
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
ATP-sensitive K+ channel openers prevent Ca2+ overload in rat cardiac mitochondria.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cyclosporine; Diazoxide; In Vitro Techniques; Ionophores; Membrane Potentials; Membrane Proteins; Microscopy, Confocal; Mitochondria, Heart; Myocardium; Oxygen Consumption; Permeability; Pinacidil; Potassium Channels; Rats; Rats, Sprague-Dawley; Valinomycin | 1999 |
Potassium channel openers depolarize hippocampal mitochondria.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Benzoates; Cytochrome c Group; Decanoic Acids; Diazoxide; Glyburide; Hippocampus; Hydroxy Acids; Intracellular Membranes; Lipid Bilayers; Membrane Potentials; Mitochondria; Mitochondrial Swelling; Potassium Channels; Potassium Chloride; Pyridines; Rats; Rats, Wistar; Valinomycin | 2001 |
Acetylcholine leads to free radical production dependent on K(ATP) channels, G(i) proteins, phosphatidylinositol 3-kinase and tyrosine kinase.
Topics: Acetylcholine; Analysis of Variance; Androstadienes; Animals; Aorta; Atropine; Cell Line; Decanoic Acids; Diazoxide; Enzyme Inhibitors; Female; Free Radical Scavengers; Genistein; GTP-Binding Protein alpha Subunits, Gi-Go; Hydroxy Acids; Ionophores; Ischemic Preconditioning; Male; Methacholine Chloride; Microscopy, Fluorescence; Muscarinic Agonists; Muscle, Smooth, Vascular; Perfusion; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Piperidines; Potassium Channel Blockers; Potassium Channels; Protein-Tyrosine Kinases; Rabbits; Rats; Reactive Oxygen Species; Receptors, Cholinergic; Signal Transduction; Tiopronin; Valinomycin; Wortmannin | 2002 |
Activation of Akt is essential for acetylcholine to trigger generation of oxygen free radicals.
Topics: Acetylcholine; Animals; Cell Line; Diazoxide; Enzyme Activation; Ionophores; Microscopy, Fluorescence; Mitochondria, Muscle; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Reactive Oxygen Species; Transfection; Valinomycin | 2003 |
Impairment of diazoxide-induced formation of reactive oxygen species and loss of cardioprotection in connexin 43 deficient mice.
Topics: Animals; Connexin 43; Diazoxide; Ischemic Preconditioning, Myocardial; Mice; Mitochondria, Heart; Myocytes, Cardiac; Protective Agents; Reactive Oxygen Species; Valinomycin; Vitamin K 3 | 2005 |
The direct physiological effects of mitoK(ATP) opening on heart mitochondria.
Topics: Adenosine Triphosphate; Animals; Benzofurans; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Decanoic Acids; Diazoxide; Ethers, Cyclic; Hydrogen-Ion Concentration; Hydroxy Acids; Light; Male; Mitochondria, Heart; Mitochondrial Swelling; Onium Compounds; Organophosphorus Compounds; Oxygen Consumption; Potassium; Potassium Channels; Rats; Rats, Sprague-Dawley; Scattering, Radiation; Uncoupling Agents; Valinomycin | 2006 |
Opening mitoKATP increases superoxide generation from complex I of the electron transport chain.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Antifungal Agents; Cromakalim; Cyclic GMP-Dependent Protein Kinases; Decanoic Acids; Diazoxide; Electron Transport Complex I; Fluorescent Dyes; Hydrogen-Ion Concentration; Hydroxy Acids; Ionophores; Male; Methacrylates; Mitochondria, Heart; Mitochondria, Liver; Models, Biological; Potassium Channels; Protein Kinase C; Rats; Rats, Sprague-Dawley; Superoxides; Thiazoles; Valinomycin; Vasodilator Agents | 2006 |
Mechanism of reactive oxygen species generation after opening of mitochondrial KATP channels.
Topics: Adenosine Triphosphate; Animals; Cromakalim; Cyclic GMP-Dependent Protein Kinases; Diazoxide; Dose-Response Relationship, Drug; Electron Transport Complex I; Fluorescent Dyes; Hydrogen Peroxide; Hydrogen-Ion Concentration; Ionophores; Male; Mitochondria, Heart; Mitochondria, Liver; Oxidants; Potassium Channels; Protein Kinase C; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Valinomycin; Vasodilator Agents | 2006 |
Increased potassium conductance of brain mitochondria induces resistance to permeability transition by enhancing matrix volume.
Topics: Alkalies; Animals; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Respiration; Diazoxide; Enzyme Activation; Hydrogen; Hydrogen Peroxide; Hydrogen-Ion Concentration; Ion Transport; Male; Mitochondria; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitochondrial Size; Molecular Mimicry; Nigericin; Potassium; Potassium Channels; Protein Kinase C; Rats; Rats, Wistar; Reactive Oxygen Species; Valinomycin | 2010 |
Respiratory uncoupling by increased H(+) or K(+) flux is beneficial for heart mitochondrial turnover of reactive oxygen species but not for permeability transition.
Topics: Animals; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cations, Monovalent; Cyclosporine; Diazoxide; Hydrogen Peroxide; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitochondrial Swelling; Osmolar Concentration; Oxidative Phosphorylation; Oxygen; Permeability; Potassium; Potassium Channels; Proton Ionophores; Protons; Rats; Reactive Oxygen Species; Uncoupling Agents; Valinomycin | 2013 |