Compounds > diazoxide

diazoxide and sirolimus

diazoxide has been researched along with sirolimus in 10 studies

Research

Studies (10)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (10.00)	29.6817
2010's	7 (70.00)	24.3611
2020's	2 (20.00)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Kwon, G; Liu, H; Marshall, CA; McDaniel, ML; Pappan, KL; Remedi, MS	1
Caballero-Díaz, C; Camps Herrero, C; Civera-Andrés, M; Ferrer-García, JC; Iranzo González-Cruz, V; Merchante-Alfaro, A; Morillas-Ariño, C; Navas-DeSolís, S; Sánchez-Juan, C	1
Goichot, B; Tabarin, A	1
Busija, DW; Dutta, S; Katakam, PV; Rutkai, I	1
Brown, RE; Hussain, K; McGuire, MF; Senniappan, S	1
Bagga, N; Chirla, DK; Gunda, RK; Panigrahy, N; Reddy, L; Sukhija, B	1
Bezirganoglu, H; Celik, K; Okur, N; Ozbek, MN; Tas, FF	1

Reviews

1 review(s) available for diazoxide and sirolimus

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

9 other study(ies) available for diazoxide and sirolimus

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Glucose-stimulated DNA synthesis through mammalian target of rapamycin (mTOR) is regulated by KATP channels: effects on cell cycle progression in rodent islets. The Journal of biological chemistry, 2006, Feb-10, Volume: 281, Issue:6 Topics: Animals; Blotting, Western; Calcium; Cell Cycle; Cell Division; Cell Proliferation; Cells, Cultured; Cytosol; Diazoxide; Dose-Response Relationship, Drug; Flow Cytometry; G2 Phase; Glucose; Glyburide; Islets of Langerhans; Male; Nifedipine; Potassium; Potassium Channels; Protein Kinases; Rats; Rats, Sprague-Dawley; S Phase; Sirolimus; Thymidine; TOR Serine-Threonine Kinases	2006
Management of malignant insulinoma. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2013, Volume: 15, Issue:9 Topics: Adult; Aged; Chemoembolization, Therapeutic; Diazoxide; Everolimus; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Insulinoma; Male; Middle Aged; Pancreatic Neoplasms; Radiotherapy; Retrospective Studies; Sirolimus; Treatment Outcome; Vasodilator Agents; Yttrium Radioisotopes	2013
Treatment: symptomatic treatment of hypoglycaemia. Annales d'endocrinologie, 2013, Volume: 74, Issue:3 Topics: Antineoplastic Agents; Blood Glucose; Diazoxide; Everolimus; Humans; Hypoglycemia; Insulinoma; Octreotide; Pancreatic Neoplasms; Protein Kinase Inhibitors; Signal Transduction; Sirolimus; Somatostatin; TOR Serine-Threonine Kinases	2013
The mechanistic target of rapamycin (mTOR) pathway and S6 Kinase mediate diazoxide preconditioning in primary rat cortical neurons. Journal of neurochemistry, 2015, Volume: 134, Issue:5 Topics: Animals; Cells, Cultured; Cerebral Cortex; Culture Media; Diazoxide; Enzyme Activation; In Vitro Techniques; Ischemic Preconditioning; Membrane Potential, Mitochondrial; Mitochondria; Nerve Tissue Proteins; Neurons; Oxygen; Oxygen Consumption; Phosphorylation; Primary Cell Culture; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Ribosomal Protein S6 Kinases; RNA Interference; RNA, Small Interfering; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases	2015
Morphoproteomics and biomedical analytics coincide with clinical outcomes in supporting a constant but variable role for the mTOR pathway in the biology of congenital hyperinsulinism of infancy. Orphanet journal of rare diseases, 2017, 12-16, Volume: 12, Issue:1 Topics: Congenital Hyperinsulinism; Diazoxide; Humans; Infant; Octreotide; Proteomics; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases	2017
Sirolimus in infants with congenital hyperinsulinism (CHI) - a single-centre experience. European journal of pediatrics, 2022, Volume: 181, Issue:1 Topics: Congenital Hyperinsulinism; Diazoxide; Glucose; Humans; Hyperinsulinism; Infant; Infant, Newborn; Mutation; Sirolimus	2022
Evaluation and management of neonatal onset hyperinsulinemic hypoglycemia: a single neonatal center experience. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2023, Volume: 36, Issue:2 Topics: Congenital Hyperinsulinism; Diazoxide; Humans; Infant; Infant, Newborn; Mutation; Retrospective Studies; Sirolimus	2023