Compounds > diazoxide

diazoxide and nn 414

diazoxide has been researched along with nn 414 in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (87.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arkhammar, PO; Bodvarsdottir, TB; Boonen, HC; Dragsted, N; Hansen, JB; Junager, F; Koch, A; MacKay, P; Mogensen, JP; Nielsen, FE; Pridal, L; Stidsen, CE; Tagmose, TM; Treppendahl, SP; Wahl, P; Worsaae, A; Ynddal, L1
Arkhammar, PO; Bondo Hansen, J; Jacobsen, P; Nielsen, FE; Wahl, P; Worsaae, A1
Arkhammar, PO; Bodvarsdottir, TB; Boonen, HC; Ebdrup, S; Fremming, T; Hansen, JB; Jensen, AF; Kornø, HT; Nielsen, FE; Stidsen, C; Wahl, P; Worsaae, A; Ynddal, L1
Baroni, M; Carosati, E; Cianchetta, G; Fremming, T; Hansen, JB; Mannhold, R; Wahl, P; Zamora, I1
Ashcroft, FM; Bondo Hansen, J; Dabrowski, M; Larsen, T; Wahl, P1
Arkhammar, PO; Donath, MY; Maedler, K; Mandrup-Poulsen, T; Spinas, GA; Sturis, J; Størling, J; Zuellig, RA1
Chan, O; Ding, Y; Evans, ML; Fan, X; Gram, DX; McCrimmon, RJ; McNay, EC; Sherwin, RS; Zhu, W1
Johnson, SW; Munhall, AC; Shen, KZ; Wu, YN1

Other Studies

8 other study(ies) available for diazoxide and nn 414

ArticleYear
6-Chloro-3-alkylamino-4H-thieno[3,2-e]-1,2,4-thiadiazine 1,1-dioxide derivatives potently and selectively activate ATP sensitive potassium channels of pancreatic beta-cells.
    Journal of medicinal chemistry, 2002, Sep-12, Volume: 45, Issue:19

    Topics: Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Binding, Competitive; Biological Availability; Blood Pressure; Body Temperature; Cell Line; Female; Glucose; Heart Rate; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male; Membrane Potentials; Mice; Muscle Contraction; Muscle, Smooth; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Drug; Stereoisomerism; Structure-Activity Relationship; Sulfonylurea Receptors; Thiadiazines

2002
2-(4-Methoxyphenoxy)-5-nitro-N-(4-sulfamoylphenyl)benzamide activates Kir6.2/SUR1 K(ATP) channels.
    Bioorganic & medicinal chemistry letters, 2004, Dec-06, Volume: 14, Issue:23

    Topics: Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Benzamides; Benzothiadiazines; Diazoxide; Islets of Langerhans; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pyridines; Rats; Receptors, Drug; Sulfonylurea Receptors; Thiadiazines

2004
New 3-alkylamino-4H-thieno-1,2,4-thiadiazine 1,1-dioxide derivatives activate ATP-sensitive potassium channels of pancreatic beta cells.
    Journal of medicinal chemistry, 2006, Jul-13, Volume: 49, Issue:14

    Topics: Animals; Biological Availability; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Crystallography, X-Ray; Cyclic S-Oxides; Female; Humans; In Vitro Techniques; Insulin; Ion Channel Gating; Islets of Langerhans; Male; Membrane Potentials; Molecular Structure; Muscle Relaxation; Muscle, Smooth; Potassium Channels, Inwardly Rectifying; Radioligand Assay; Rats; Rats, Sprague-Dawley; Rats, Wistar; Rats, Zucker; Structure-Activity Relationship; Thiadiazines

2006
Virtual screening for novel openers of pancreatic K(ATP) channels.
    Journal of medicinal chemistry, 2007, May-03, Volume: 50, Issue:9

    Topics: ATP-Binding Cassette Transporters; Cell Line; Databases, Factual; Humans; Insulin; Insulin Secretion; Insulin-Secreting Cells; Ion Channel Gating; Membrane Potentials; Models, Molecular; Potassium Channels; Potassium Channels, Inwardly Rectifying; Quantitative Structure-Activity Relationship; Receptors, Drug; Sulfonylurea Receptors

2007
Potent and selective activation of the pancreatic beta-cell type K(ATP) channel by two novel diazoxide analogues.
    Diabetologia, 2003, Volume: 46, Issue:10

    Topics: Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cyclic S-Oxides; Diazoxide; Female; Humans; Islets of Langerhans; Mice; Muscle, Smooth; Myocardium; Oocytes; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Receptors, Drug; Sulfonylurea Receptors; Xenopus laevis

2003
Glucose- and interleukin-1beta-induced beta-cell apoptosis requires Ca2+ influx and extracellular signal-regulated kinase (ERK) 1/2 activation and is prevented by a sulfonylurea receptor 1/inwardly rectifying K+ channel 6.2 (SUR/Kir6.2) selective potassiu
    Diabetes, 2004, Volume: 53, Issue:7

    Topics: Aged; Apoptosis; ATP-Binding Cassette Transporters; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Channels, L-Type; Cells, Cultured; Cyclic S-Oxides; Diazoxide; Drug Synergism; Enzyme Activation; Glucose; Humans; Interleukin-1; Islets of Langerhans; Middle Aged; Mitogen-Activated Protein Kinases; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Sulfonylurea Receptors; Tolbutamide

2004
Activation of ATP-sensitive K+ channels in the ventromedial hypothalamus amplifies counterregulatory hormone responses to hypoglycemia in normal and recurrently hypoglycemic rats.
    Diabetes, 2005, Volume: 54, Issue:11

    Topics: Animals; Blood Glucose; Bridged Bicyclo Compounds, Heterocyclic; Carbonates; Cyclic S-Oxides; Diazoxide; Epinephrine; Glucagon; Glucose; Hypoglycemia; Male; Potassium; Potassium Channels, Inwardly Rectifying; Rats; Rats, Sprague-Dawley; Ventromedial Hypothalamic Nucleus

2005
AMP kinase regulates ligand-gated K-ATP channels in substantia nigra dopamine neurons.
    Neuroscience, 2016, 08-25, Volume: 330

    Topics: Action Potentials; AMP-Activated Protein Kinases; Animals; Biphenyl Compounds; Bridged Bicyclo Compounds, Heterocyclic; Central Nervous System Agents; Cyclic S-Oxides; Diazoxide; Dopaminergic Neurons; Enzyme Inhibitors; KATP Channels; Male; Pars Compacta; Patch-Clamp Techniques; Pyrazoles; Pyrimidines; Pyrones; Rats, Sprague-Dawley; Thiophenes; Tissue Culture Techniques

2016