diazoxide has been researched along with nicorandil in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (6.90) | 18.7374 |
| 1990's | 5 (17.24) | 18.2507 |
| 2000's | 13 (44.83) | 29.6817 |
| 2010's | 7 (24.14) | 24.3611 |
| 2020's | 2 (6.90) | 2.80 |
| Authors | Studies |
|---|---|
| Horio, Y; Isomoto, S; Kondo, C; Kurachi, Y; Matsumoto, S; Shindo, T; Yamada, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Dunne, MJ | 1 |
| Garrino, MG; Henquin, JC; Plant, TD | 2 |
| Attolini, L; Bruguerolle, B; Gantenbein, M | 1 |
| Atwal, KS | 1 |
| Hori, M; Horio, Y; Isomoto, S; Kitakaze, M; Kondo, C; Kurachi, Y; Okuyama, Y; Satoh, E; Shindo, T; Yamada, M | 1 |
| D'hahan, N; Jacquet, H; Moreau, C; Prost, AL; Vivaudou, M | 1 |
| Ashcroft, FM; Gribble, FM | 1 |
| Asakura, M; Asanuma, H; Harada, K; Hori, M; Kitakaze, M; Kuzuya, T; Mori, H; Node, K; Ogita, H; Sakata, Y; Sanada, S; Shinozaki, Y; Takashima, S | 1 |
| Chiang, HT; Li, HF; Wu, SN | 1 |
| Fujita, A; Kurachi, Y; Matsuoka, T; Matsushita, K | 1 |
| Bienengraeber, M; Dzeja, PP; Ozcan, C; Terzic, A | 1 |
| Dairaku, Y; Harada, N; Ikeda, Y; Iwamoto, H; Iwatate, M; Kametani, R; Kawamura, S; Kimura, M; Matsuzaki, M; Miura, T; Okamura, T; Yamada, M | 1 |
| Debska, G; Elger, CE; Kicinska, A; Kunz, WS; May, R; Skalska, J; Szewczyk, A | 1 |
| Busija, DW; Horiguchi, T; Kis, B; Nagy, K; Rajapakse, NC; Snipes, JA | 1 |
| Duchen, MR; Hausenloy, DJ; Mani-Babu, S; Yellon, DM | 1 |
| Dairaku, Y; Harada, N; Kametani, R; Kawamura, S; Matsuzaki, M; Miura, T; Shibuya, M; Wang, R | 1 |
| Miki, T; Miura, T | 1 |
| Miura, T | 1 |
| Bahler, CK; Chang, M; Chowdhury, UR; Fautsch, MP; Hann, CR; Resch, ZT; Romero, MF | 1 |
| Chowdhury, UR; Fautsch, MP; Holman, BH | 1 |
| Dosa, PI; Fautsch, MP; Roy Chowdhury, U | 1 |
| Adachi, T; Fujisawa, S; Hongoh, M; Ohba, T; Ono, K; Shimbo, T | 1 |
| Bahler, CK; Fautsch, MP; Holman, BH; Roy Chowdhury, U | 1 |
| Gao, F; He, B; Huang, R; Ma, L; Wan, Y; Wang, C; Wang, L; Wang, S; Zhang, M; Zhu, D | 1 |
| Aftab, M; Cheng, L; Cleveland, JC; Fullerton, DA; Ghincea, CV; Ikeno, Y; Meng, X; Reece, TB; Roda, GF; Weyant, MJ | 1 |
5 review(s) available for diazoxide and nicorandil
| Article | Year |
|---|---|
Pharmacology and structure-activity relationships for KATP modulators: tissue-selective KATP openers.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Antihypertensive Agents; Benzopyrans; Cardiovascular Diseases; Cromakalim; Diazoxide; Guanidines; Guinea Pigs; Minoxidil; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Picolines; Pinacidil; Potassium Channels; Pyrans; Pyrroles; Radioligand Assay; Rats; Structure-Activity Relationship; Vasodilator Agents | 1994 |
New windows on the mechanism of action of K(ATP) channel openers.
Topics: Adenosine Triphosphate; Animals; Binding Sites; Cromakalim; Diazoxide; Humans; Minoxidil; Nicorandil; Pinacidil; Potassium Channels | 2000 |
[Activation of ATP-sensitive K+ channels by ADP and K+ channel openers: homology model of sulfonylurea receptor carboxyl-termini].
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Sequence; ATP-Binding Cassette Transporters; Diazoxide; Drug Design; Humans; Molecular Sequence Data; Nicorandil; Nucleotides; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Binding; Protein Conformation; Receptors, Drug; Sequence Homology, Amino Acid; Sulfonylurea Receptors | 2001 |
ATP-sensitive K+ channel openers: old drugs with new clinical benefits for the heart.
Topics: Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Disease; Diazoxide; Glyburide; Humans; Ion Channel Gating; Myocardial Reperfusion Injury; Nicorandil; Pinacidil; Potassium Channel Blockers; Potassium Channels; Randomized Controlled Trials as Topic; Vasodilator Agents | 2003 |
ATP sensitive potassium channel openers: A new class of ocular hypotensive agents.
Topics: Animals; Antihypertensive Agents; Cromakalim; Diazoxide; Glaucoma; Humans; Intraocular Pressure; KATP Channels; Nicorandil; Trabecular Meshwork | 2017 |
24 other study(ies) available for diazoxide and nicorandil
| Article | Year |
|---|---|
Sulphonylurea receptor 2B and Kir6.1 form a sulphonylurea-sensitive but ATP-insensitive K+ channel.
Topics: Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Cloning, Molecular; Glyburide; Guanidines; Guanosine Diphosphate; Guanosine Triphosphate; Hypoglycemic Agents; KATP Channels; Macromolecular Substances; Magnesium; Mice; Molecular Sequence Data; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Patch-Clamp Techniques; Pinacidil; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Sulfonylurea Compounds; Sulfonylurea Receptors; Uridine Diphosphate; Vasodilator Agents | 1997 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Effects of pinacidil, RP 49356 and nicorandil on ATP-sensitive potassium channels in insulin-secreting cells.
Topics: Adenoma, Islet Cell; Adenosine Triphosphate; Diazoxide; Glucose; Guanidines; Humans; Insulin; Insulinoma; Islets of Langerhans; Membrane Potentials; Niacinamide; Nicorandil; Pancreatic Neoplasms; Picolines; Pinacidil; Potassium Channels; Pyrans; Rubidium Radioisotopes; Tumor Cells, Cultured | 1990 |
Comparison of the effects of putative activators of K+ channels on pancreatic B-cell function.
Topics: Animals; Benzopyrans; Cromakalim; Diazoxide; Guanidines; In Vitro Techniques; Islets of Langerhans; Mice; Minoxidil; Niacinamide; Nicorandil; Pinacidil; Potassium Channels; Pyrroles; Vasodilator Agents | 1989 |
Effects of putative activators of K+ channels in mouse pancreatic beta-cells.
Topics: Adenosine Triphosphate; Animals; Benzopyrans; Cromakalim; Diazoxide; Electrophysiology; Female; Glucose; Guanidines; Homeostasis; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Membrane Potentials; Mice; Minoxidil; Niacinamide; Nicorandil; Pinacidil; Potassium Channels; Pyrroles; Rubidium Radioisotopes | 1989 |
Effect of four potassium channel agonists on bupivacaine-induced toxicity in mice.
Topics: Animals; Benzopyrans; Bupivacaine; Cromakalim; Diazoxide; Dose-Response Relationship, Drug; Guanidines; Male; Mice; Mice, Inbred Strains; Niacinamide; Nicorandil; Pinacidil; Potassium Channels; Pyrroles; Seizures | 1995 |
The effects of nucleotides and potassium channel openers on the SUR2A/Kir6.2 complex K+ channel expressed in a mammalian cell line, HEK293T cells.
Topics: Adenosine Triphosphate; ATP-Binding Cassette Transporters; Cell Line; Diazoxide; Guanidines; Humans; Membrane Potentials; Niacinamide; Nicorandil; Patch-Clamp Techniques; Pinacidil; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Sulfonylurea Receptors; Uridine Diphosphate | 1998 |
The molecular basis of the specificity of action of K(ATP) channel openers.
Topics: Amino Acid Sequence; Animals; ATP-Binding Cassette Transporters; Cell Membrane; Cricetinae; Cromakalim; Diazoxide; Ion Channel Gating; Mice; Models, Molecular; Molecular Sequence Data; Muscle, Skeletal; Mutagenesis, Site-Directed; Neurons; Nicorandil; Oocytes; Pancreas; Pinacidil; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Isoforms; Protein Structure, Secondary; Rats; Receptors, Drug; Recombinant Fusion Proteins; Sulfonylurea Receptors | 2000 |
Role of mitochondrial and sarcolemmal K(ATP) channels in ischemic preconditioning of the canine heart.
Topics: Adenosine Triphosphate; Animals; Calcium Channel Blockers; Collateral Circulation; Coronary Circulation; Cromakalim; Decanoic Acids; Diazoxide; Dogs; Heart; Hemodynamics; Hydroxy Acids; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Mitochondria, Heart; Myocardial Infarction; Myocardial Reperfusion Injury; Nicorandil; Potassium Channel Blockers; Potassium Channels; Sarcolemma; Vasodilator Agents | 2001 |
Characterization of ATP-sensitive potassium channels functionally expressed in pituitary GH3 cells.
Topics: 2,4-Dinitrophenol; Action Potentials; Adenoma; Adenosine Triphosphate; Animals; Aristolochic Acids; Calcium Chloride; Diazoxide; Disulfides; Enzyme Activation; Ion Transport; Magnesium; Melitten; Nicorandil; Phenanthrenes; Phospholipases A; Phospholipases A2; Pituitary Gland, Anterior; Pituitary Neoplasms; Potassium; Potassium Channels; Pyridines; Rats; Sodium Cyanide; Tumor Cells, Cultured | 2000 |
Potassium channel openers protect cardiac mitochondria by attenuating oxidant stress at reoxygenation.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Cardiotonic Agents; Cytochrome c Group; Decanoic Acids; Diazoxide; Energy Metabolism; Free Radical Scavengers; Hydroxy Acids; Mitochondria; Myocardial Reperfusion Injury; Myocardium; Nicorandil; Oxidative Phosphorylation; Oxidative Stress; Oxygen Consumption; Potassium; Potassium Channel Blockers; Potassium Channels; Rats; Reactive Oxygen Species; Succinate Dehydrogenase; Vasodilator Agents | 2002 |
Effect of ischemic preconditioning and mitochondrial KATP channel openers on chronic left ventricular remodeling in the ischemic-reperfused rat heart.
Topics: Animals; Diazoxide; Heart Rate; Ion Channel Gating; Ischemic Preconditioning; Male; Membrane Proteins; Mitochondria, Heart; Myocardial Reperfusion; Nicorandil; Potassium Channels; Rats; Rats, Sprague-Dawley; Ventricular Function, Left | 2002 |
Opening of potassium channels modulates mitochondrial function in rat skeletal muscle.
Topics: Animals; Anti-Arrhythmia Agents; Cell Line; Cell Respiration; Diazoxide; Glutamic Acid; Glyburide; Malates; Membrane Potentials; Mitochondria, Muscle; Muscle, Skeletal; Myoblasts; Nicorandil; Oxidation-Reduction; Oxygen; Potassium Channels; Rats | 2002 |
Diazoxide induces delayed pre-conditioning in cultured rat cortical neurons.
Topics: Animals; Cell Death; Cell Hypoxia; Cell Survival; Cells, Cultured; Cerebral Cortex; Cromakalim; Decanoic Acids; Diazoxide; Enzyme Activation; Enzyme Inhibitors; Glucose; Glyburide; Hydroxy Acids; Ischemic Preconditioning; Mitochondria; Neurons; Neuroprotective Agents; Nicorandil; Nitro Compounds; Oxidative Stress; Propionates; Rats; Rats, Wistar; Succinate Dehydrogenase; Superoxides; Time Factors | 2003 |
Preconditioning protects by inhibiting the mitochondrial permeability transition.
Topics: Animals; Cell Hypoxia; Diazoxide; Fluorescence; Intracellular Membranes; Ischemic Preconditioning, Myocardial; Lasers; Male; Membrane Potentials; Microscopy, Confocal; Mitochondria, Heart; Myocytes, Cardiac; Nicorandil; Oxidative Stress; Permeability; Rats; Rats, Sprague-Dawley; Rhodamines | 2004 |
NO donor-activated PKC-delta plays a pivotal role in ischemic myocardial protection through accelerated opening of mitochondrial K-ATP channels.
Topics: Animals; Antihypertensive Agents; Diazoxide; Enzyme Activation; Heart Rate; Isoenzymes; Membrane Proteins; Myocardial Ischemia; Nicorandil; Nitric Oxide; Potassium Channels; Protein Kinase C; Protein Kinase C-delta; Rats; Rats, Sprague-Dawley | 2004 |
A new mechanism and strategy for inhibiting thrombus formation in the artery.
Topics: Animals; Arteries; Diazoxide; Endothelium, Vascular; Humans; Nicorandil; Thrombosis; Vasodilator Agents | 2009 |
ATP-sensitive potassium (KATP) channel activation decreases intraocular pressure in the anterior chamber of the eye.
Topics: Aged; Aged, 80 and over; Animals; Cells, Cultured; Diazoxide; Female; Glyburide; Guanidines; Humans; Immunohistochemistry; Intraocular Pressure; KATP Channels; Male; Middle Aged; Nicorandil; Organ Culture Techniques; Patch-Clamp Techniques; Pyridines; Rats; Rats, Inbred BN; Reverse Transcriptase Polymerase Chain Reaction; Tonometry, Ocular; Trabecular Meshwork; Vasodilator Agents | 2011 |
ATP-sensitive potassium (K(ATP)) channel openers diazoxide and nicorandil lower intraocular pressure in vivo.
Topics: Animals; Diazoxide; Eye; Immunohistochemistry; Intraocular Pressure; KATP Channels; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Models, Animal; Nicorandil; Protein Subunits; Vasodilator Agents | 2013 |
In vitro effect of nicorandil on the carbachol-induced contraction of the lower esophageal sphincter of the rat.
Topics: Animals; Carbachol; Diazoxide; Dose-Response Relationship, Drug; Esophageal Sphincter, Lower; Glyburide; In Vitro Techniques; KATP Channels; Muscle Contraction; NG-Nitroarginine Methyl Ester; Nicorandil; Oxadiazoles; Peptides; Pinacidil; Potassium; Quinoxalines; Rats | 2016 |
ATP-sensitive potassium (KATP) channel openers diazoxide and nicorandil lower intraocular pressure by activating the Erk1/2 signaling pathway.
Topics: Adult; Aged; Aged, 80 and over; Animals; Butadienes; Cells, Cultured; Diazoxide; Enzyme Activation; Humans; Infant; Intraocular Pressure; Ion Channel Gating; KATP Channels; MAP Kinase Signaling System; Mice, Inbred C57BL; Middle Aged; Nicorandil; Nitriles; Ocular Hypotension; Perfusion; Phosphorylation | 2017 |
Nicorandil Ameliorates Doxorubicin-Induced Cardiotoxicity in Rats, as Evaluated by 7 T Cardiovascular Magnetic Resonance Imaging.
Topics: Animals; Cardiotoxicity; Diazoxide; Doxorubicin; Inflammation; Magnetic Resonance Imaging; Male; Nicorandil; Rats; Rats, Sprague-Dawley; Stroke Volume; Ventricular Function, Left | 2023 |
Direct and indirect activation of the adenosine triphosphate-sensitive potassium channel to induce spinal cord ischemic metabolic tolerance.
Topics: Adenosine Triphosphate; Animals; Diazoxide; Ischemia; Male; Mice; Mice, Inbred C57BL; Nicorandil; Nitric Oxide; Potassium Channels; Spinal Cord Injuries | 2023 |