diazoxide and nateglinide

diazoxide has been researched along with nateglinide in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (45.45)18.2507
2000's3 (27.27)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dan, K; Fujita, T; Hirose, H; Ito, K; Kanda, N; Kato, R; Maruyama, H; Saruta, T; Seto, Y1
Fujitani, S; Yada, T1
Dan, K; Fujita, H; Fujita, T; Kato, R; Seto, Y1
Akiyoshi, M; Fujitani, S; Ikenoue, T; Kondo, N; Maki, T; Okazaki, K1
Kikuchi, M; Niki, I; Oka, Y; Sakurada, M; Tsukuda, K1
Ball, AJ; Flatt, PR; McClenaghan, NH1

Reviews

1 review(s) available for diazoxide and nateglinide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

10 other study(ies) available for diazoxide and nateglinide

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Effects of D-phenylalanine-derivative hypoglycemic agent A-4166 on pancreatic alpha- and beta-cells: comparative study with glibenclamide.
    Pharmacology, 1995, Volume: 50, Issue:3

    Topics: Analysis of Variance; Animals; Cyclohexanes; Diazoxide; Drug Interactions; Glucagon; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Nateglinide; Perfusion; Phenylalanine; Rats; Rats, Wistar

1995
A novel D-phenylalanine-derivative hypoglycemic agent A-4166 increases cytosolic free Ca2+ in rat pancreatic beta-cells by stimulating Ca2+ influx.
    Endocrinology, 1994, Volume: 134, Issue:3

    Topics: Animals; Calcium; Cyclohexanes; Cytosol; Diazoxide; Dose-Response Relationship, Drug; Glucose; Hypoglycemic Agents; Islets of Langerhans; Nateglinide; Nitrendipine; Phenylalanine; Potassium Channels; Rats; Rats, Wistar; Sulfonylurea Compounds

1994
Stimulating activity of A-4166 on insulin release in in situ hamster pancreatic perfusion.
    Pharmacology, 1995, Volume: 51, Issue:4

    Topics: Animals; Blood Glucose; Cricetinae; Cyclohexanes; Diazoxide; Drug Interactions; Glyburide; Hypoglycemic Agents; Insulin; Islets of Langerhans; Male; Mesocricetus; Nateglinide; Pancreas; Perfusion; Phenylalanine; Vasodilator Agents

1995
Hypoglycaemic and insulinotropic effects of a novel oral antidiabetic agent, (-)-N-(trans-4-isopropylcyclohexanecarbonyl)-D-phenylalanine (A-4166).
    British journal of pharmacology, 1997, Volume: 120, Issue:1

    Topics: Animals; Binding, Competitive; Blood Glucose; Calcium; Cell Line; Cyclohexanes; Diazoxide; Diuretics; Dogs; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Nateglinide; Phenylalanine; Rats; Rats, Wistar; Sodium Chloride Symporter Inhibitors; Stimulation, Chemical

1997
Insulin secretion from isolated rat islets induced by the novel hypoglycemic agent A-4166, a derivative of D-phenylalanine.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1998, Volume: 30, Issue:1

    Topics: Animals; ATP-Binding Cassette Transporters; Biological Availability; Calcium; Cell Line; Cyclohexanes; Diazoxide; Epinephrine; Glucose; Glyburide; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Male; Nateglinide; Phenylalanine; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Drug; Rubidium; Somatostatin; Stereoisomerism; Sulfonylurea Receptors; Tolbutamide

1998
Alterations of insulin secretion following long-term manipulation of ATP-sensitive potassium channels by diazoxide and nateglinide.
    Biochemical pharmacology, 2005, Jan-01, Volume: 69, Issue:1

    Topics: Adenosine Triphosphate; Cell Line; Cyclohexanes; Diazoxide; Drug Administration Schedule; Humans; Insulin; Insulin Secretion; Nateglinide; Phenylalanine; Potassium Channel Blockers; Potassium Channels

2005