diazoxide and naloxone

diazoxide has been researched along with naloxone in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.56)18.2507
2000's8 (44.44)29.6817
2010's9 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Gozalbes, R; Pineda-Lucena, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Baeyens, JM; Barrios, M; Robles, LI1
Ahmadi, S; Djahanguiri, B; Jafari, MR; Zarrindast, MR1
Alves, DP; Castro, MS; Duarte, ID; Francischi, JN; Perez, AC; Soares, AC1
Djahanguiri, B; Jafari, MR; Shafaghi, B; Zarrindast, MR1
Mohajeri, S; Zarrindast, MR1
Garg, GR; Halder, S; Khanna, N; Malhotra, RS; Mehta, AK; Sharma, KK1
Giovani de Oliveira Nascimento, C; Giusti-Paiva, A; Pereira de Ávila, MA1

Reviews

1 review(s) available for diazoxide and naloxone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

17 other study(ies) available for diazoxide and naloxone

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
ATP-sensitive K+ channel openers inhibit morphine withdrawal.
    European journal of pharmacology, 1994, Jan-04, Volume: 251, Issue:1

    Topics: Adenosine Triphosphate; Animals; Behavior, Animal; Benzopyrans; Body Weight; Cromakalim; Diazoxide; Dose-Response Relationship, Drug; Female; Injections, Intraventricular; Injections, Subcutaneous; Mice; Mice, Inbred Strains; Morphine; Naloxone; Potassium Channels; Pyrroles; Substance Withdrawal Syndrome

1994
Influence of central administration ATP-dependent K+ channel on morphine state-dependent memory of passive avoidance.
    European journal of pharmacology, 2004, Mar-08, Volume: 487, Issue:1-3

    Topics: Animals; ATP-Binding Cassette Transporters; Avoidance Learning; Diazoxide; Glyburide; Injections, Intraventricular; KATP Channels; Male; Memory; Mice; Morphine; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Narcotics; Parasympathetic Nervous System; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Scopolamine

2004
Additive antinociceptive effect of the combination of diazoxide, an activator of ATP-sensitive K+ channels, and sodium nitroprusside and dibutyryl-cGMP.
    European journal of pharmacology, 2004, Apr-05, Volume: 489, Issue:1-2

    Topics: Analgesics; Animals; Benzimidazoles; Diazoxide; Dibutyryl Cyclic GMP; Dinoprostone; Drug Synergism; Endorphins; Hyperalgesia; Kinetics; Male; Membrane Proteins; Naloxone; Narcotic Antagonists; Nitric Oxide; Nitroprusside; Pain Measurement; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar

2004
Influence of potassium channel modulators on morphine state-dependent memory of passive avoidance.
    Behavioural pharmacology, 2004, Volume: 15, Issue:2

    Topics: Adenosine Triphosphate; Animals; Atropine; Avoidance Learning; Diazoxide; Glyburide; Male; Memory; Mice; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; Potassium Channel Blockers; Potassium Channels

2004
Influence of ATP-dependent K+ channels on nicotine-induced inhibition of withdrawal in morphine-dependent mice.
    European journal of pharmacology, 2006, Dec-15, Volume: 552, Issue:1-3

    Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Behavior, Animal; Diarrhea; Diazoxide; Dose-Response Relationship, Drug; Ganglionic Stimulants; Glyburide; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Nicotine; Potassium Channels, Inwardly Rectifying; Substance Withdrawal Syndrome

2006
Interaction of morphine and potassium channel openers on experimental models of pain in mice.
    Fundamental & clinical pharmacology, 2011, Volume: 25, Issue:4

    Topics: Animals; Calcium Channel Agonists; Cromakalim; Diazoxide; Drug Interactions; Drug Therapy, Combination; Female; Glyburide; Injections, Intraperitoneal; Male; Mice; Mice, Inbred Strains; Minoxidil; Morphine; Naloxone; Pain; Pain Measurement; Potassium Channels

2011
The peripheral antinociceptive effect induced by the heme oxygenase/carbon monoxide pathway is associated with ATP-sensitive K+ channels.
    European journal of pharmacology, 2014, Mar-05, Volume: 726

    Topics: Analgesics; Animals; Biliverdine; Carbon Monoxide; Carrageenan; Diazoxide; Drug Interactions; Ferrous Compounds; Glyburide; Heme Oxygenase (Decyclizing); Hemin; KATP Channels; Male; Metalloporphyrins; Naloxone; Nociception; Peripheral Nervous System; Potassium Channel Blockers; Protoporphyrins; Rats; Rats, Wistar; Signal Transduction

2014