diazoxide and n-cyano-n'-(1,1-dimethylpropyl)-n''-(3-pyridinyl)guanidine

diazoxide has been researched along with n-cyano-n'-(1,1-dimethylpropyl)-n''-(3-pyridinyl)guanidine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (18.18)18.2507
2000's8 (72.73)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andres, H; Bray, K; Manley, PW; Quast, U1
Agerholm, PC; Arkhammar, PO; Hansen, JB; Mogensen, JP; Tagmose, TM; Wahl, P; Worsaae, A1
Balsamo, A; Bianucci, AM; Calderone, V; Coi, A; Digiacomo, M; Rapposelli, S; Testai, L1
Aguilar-Bryan, L; Bryan, J; Dörschner, H; Gross, I; Schwanstecher, C; Schwanstecher, M; Sieverding, C1
Liu, Y; Marbán, E; O'Rourke, B; Ren, G; Seharaseyon, J1
Grover, GJ; Jilkina, O; Kupriyanov, VV; Kuzio, B1
Cohen, MV; Downey, JM; Garlid, KD; Grover, GJ; Krieg, T; Oldenburg, O; Yang, XM1
Brune, ME; Buckner, SA; Coghlan, M; Daza, A; Fey, TA; Gopalakrishnan, M; Milicic, I1
Nakaya, H; Sato, T1
Gaisano, HY; Kang, Y; Ng, B; Sun, H; Xie, H1
Bahler, CK; Chang, M; Chowdhury, UR; Fautsch, MP; Hann, CR; Resch, ZT; Romero, MF1

Other Studies

11 other study(ies) available for diazoxide and n-cyano-n'-(1,1-dimethylpropyl)-n''-(3-pyridinyl)guanidine

ArticleYear
Synthesis of and radioligand binding studies with a tritiated pinacidil analogue: receptor interactions of structurally different classes of potassium channel openers and blockers.
    Journal of medicinal chemistry, 1993, Jul-09, Volume: 36, Issue:14

    Topics: Animals; Binding Sites; Drug Interactions; Guanidines; Muscle, Smooth, Vascular; Pinacidil; Potassium Channels; Pyridines; Rats; Structure-Activity Relationship; Vasodilator Agents

1993
Phenylcyanoguanidines as inhibitors of glucose-induced insulin secretion from beta cells.
    Bioorganic & medicinal chemistry letters, 2001, Jul-09, Volume: 11, Issue:13

    Topics: Cell Line; Glucose; Guanidines; Humans; In Vitro Techniques; Insulin; Insulin Antagonists; Insulin Secretion; Islets of Langerhans

2001
Predictive models, based on classification algorithms, for compounds potentially active as mitochondrial ATP-sensitive potassium channel openers.
    Bioorganic & medicinal chemistry, 2009, Aug-01, Volume: 17, Issue:15

    Topics: Algorithms; Benzopyrans; Cardiotonic Agents; KATP Channels; Models, Chemical; Molecular Structure; Quantitative Structure-Activity Relationship; Spiro Compounds

2009
Potassium channel openers require ATP to bind to and act through sulfonylurea receptors.
    The EMBO journal, 1998, Oct-01, Volume: 17, Issue:19

    Topics: Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Binding Sites; Binding, Competitive; Cricetinae; Diazoxide; Glyburide; Guanidines; Humans; Mutation; Peptide Fragments; Pinacidil; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Isoforms; Pyridines; Receptors, Drug; Recombinant Proteins; Sulfonylurea Receptors

1998
Pharmacological comparison of native mitochondrial K(ATP) channels with molecularly defined surface K(ATP) channels.
    Molecular pharmacology, 2001, Volume: 59, Issue:2

    Topics: Animals; ATP-Binding Cassette Transporters; Cells, Cultured; Diazoxide; Glyburide; Guanidines; Heart Ventricles; Humans; KATP Channels; Membrane Proteins; Mitochondria, Heart; Myocardium; Patch-Clamp Techniques; Pinacidil; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pyridines; Rabbits; Receptors, Drug; Recombinant Proteins; Sulfonylurea Receptors; Vasodilator Agents

2001
Effects of K(ATP) channel openers, P-1075, pinacidil, and diazoxide, on energetics and contractile function in isolated rat hearts.
    Journal of molecular and cellular cardiology, 2002, Volume: 34, Issue:4

    Topics: 2,4-Dinitrophenol; Adenosine Triphosphate; Animals; Diazoxide; Guanidines; Heart; In Vitro Techniques; Magnetic Resonance Spectroscopy; Male; Myocardial Contraction; Myocardium; Oxidative Phosphorylation; Oxygen Consumption; Perfusion; Phosphocreatine; Pinacidil; Potassium Channel Blockers; Potassium Channels; Pyridines; Rats; Rats, Sprague-Dawley; Vasodilator Agents

2002
P1075 opens mitochondrial K(ATP) channels and generates reactive oxygen species resulting in cardioprotection of rabbit hearts.
    Journal of molecular and cellular cardiology, 2003, Volume: 35, Issue:9

    Topics: Animals; Brain Chemistry; Decanoic Acids; Diazoxide; Glyburide; Guanidines; Hydroxy Acids; Ischemic Preconditioning, Myocardial; Liposomes; Mitochondria, Heart; Myocardial Infarction; Myocardial Ischemia; Potassium Channels; Pyridines; Rabbits; Rats; Reactive Oxygen Species; Vasodilator Agents

2003
Pharmacological characterization of urinary bladder smooth muscle contractility following partial bladder outlet obstruction in pigs.
    European journal of pharmacology, 2006, Feb-17, Volume: 532, Issue:1-2

    Topics: Adenosine Triphosphate; Amides; Animals; Benzophenones; Carbachol; Cholinergic Agonists; Cromakalim; Cyclic S-Oxides; Diazoxide; Dose-Response Relationship, Drug; Electric Stimulation; Female; Guanidines; Histamine; Hypertrophy; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Potassium Channels; Potassium Chloride; Pyridines; Quinolones; Serotonin; Serotonin Agents; Swine; Urinary Bladder; Urinary Bladder Neck Obstruction; Vasodilator Agents

2006
P-1075 exerts diverse modulatory effects on mitochondrial ATP-sensitive K+ channels in rabbit ventricular myocytes.
    Journal of cardiovascular pharmacology, 2006, Volume: 47, Issue:2

    Topics: 2,4-Dinitrophenol; Animals; Cells, Cultured; Diazoxide; Flavoproteins; Guanidines; Heart Ventricles; Kinetics; Mitochondria, Heart; Myocytes, Cardiac; Potassium Channels; Pyridines; Rabbits; Uncoupling Agents; Vasodilator Agents

2006
Syntaxin-1A inhibition of P-1075, cromakalim, and diazoxide actions on mouse cardiac ATP-sensitive potassium channel.
    Cardiovascular research, 2008, Dec-01, Volume: 80, Issue:3

    Topics: Animals; Cell Line; Cells, Cultured; Cromakalim; Diazoxide; Dose-Response Relationship, Drug; Guanidines; Humans; KATP Channels; Kidney; Male; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Patch-Clamp Techniques; Potassium Channels, Inwardly Rectifying; Pyridines; Syntaxin 1; Vasodilator Agents

2008
ATP-sensitive potassium (KATP) channel activation decreases intraocular pressure in the anterior chamber of the eye.
    Investigative ophthalmology & visual science, 2011, Aug-16, Volume: 52, Issue:9

    Topics: Aged; Aged, 80 and over; Animals; Cells, Cultured; Diazoxide; Female; Glyburide; Guanidines; Humans; Immunohistochemistry; Intraocular Pressure; KATP Channels; Male; Middle Aged; Nicorandil; Organ Culture Techniques; Patch-Clamp Techniques; Pyridines; Rats; Rats, Inbred BN; Reverse Transcriptase Polymerase Chain Reaction; Tonometry, Ocular; Trabecular Meshwork; Vasodilator Agents

2011