diazoxide has been researched along with glutamic acid in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (33.33) | 18.2507 |
| 2000's | 10 (55.56) | 29.6817 |
| 2010's | 2 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Ben-Ari, Y | 1 |
| Ben-Ari, Y; Crépel, V; Rovira, C | 1 |
| Baraldi, M; Bertolino, M; Braghiroli, D; Costa, E; DiBella, M; Parenti, C; Vicini, S | 1 |
| Hankins, MW; Ikeda, H | 1 |
| Dorman, RV; Ruehr, ML; Zhang, L | 1 |
| Covey, DF; He, YY; Hsu, CY; Hu, R; Hu, Y; Yamada, KA | 1 |
| Haller, M; Mironov, SL; Richter, DW | 1 |
| Debska, G; Elger, CE; Kicinska, A; Kunz, WS; May, R; Skalska, J; Szewczyk, A | 1 |
| Akaike, A; Honda, Y; Kashii, S; Yamauchi, T; Yasuyoshi, H; Zhang, S | 1 |
| Akao, M; Baumgartner, WA; Chong, TH; Johnston, MV; Li, RA; Marbán, E; Teshima, Y | 1 |
| Chan, SL; Elmér, E; Hansson, M; Liu, D; Lu, C; Mattson, MP; Slevin, JR | 1 |
| Nakagawa, I; Nakase, H; Noriyama, Y; Ogawa, Y; Sakaki, T; Yamashita, M | 1 |
| Bari, F; Busija, DW; Kis, B; Nagy, K; Rajapakse, NC | 1 |
| Bøtker, HE; Kristiansen, SB; Nielsen, TT; Nielsen-Kudsk, JE | 1 |
| Chai, Y; Ding, JH; Hu, G; Niu, L; Sun, XL | 1 |
| Atlasz, T; Babai, N; Bari, F; Domoki, F; Gabriel, R; Kiss, P; Reglodi, D; Tamas, A | 1 |
| Ballard, ED; Farmer, C; Henn, FA; Henter, ID; Kadriu, B; Lener, MS; Niciu, MJ; Nugent, AC; Park, LT; Park, M; Yazdian, A; Yuan, S; Zarate, CA | 1 |
1 trial(s) available for diazoxide and glutamic acid
| Article | Year |
|---|---|
Clinical Trial of the Potassium Channel Activator Diazoxide for Major Depressive Disorder Halted Due to Intolerability.
Topics: Adult; Aged; Cross-Over Studies; Depressive Disorder, Major; Depressive Disorder, Treatment-Resistant; Diazoxide; Dose-Response Relationship, Drug; Double-Blind Method; Early Termination of Clinical Trials; Female; Glutamic Acid; Humans; Male; Middle Aged; Potassium Channels; Psychiatric Status Rating Scales; Treatment Outcome | 2018 |
17 other study(ies) available for diazoxide and glutamic acid
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Modulation of ATP sensitive K+ channels: a novel strategy to reduce the deleterious effects of anoxia.
Topics: Adenosine Triphosphate; Animals; Diazoxide; Galanin; Glutamates; Glutamic Acid; Glyburide; Hippocampus; Hypoxia, Brain; In Vitro Techniques; Male; Membrane Potentials; Peptides; Potassium Channels; Rats; Rats, Inbred Strains; Somatostatin | 1990 |
The K+ channel opener diazoxide enhances glutamatergic currents and reduces GABAergic currents in hippocampal neurons.
Topics: Adenosine Triphosphate; Animals; Diazoxide; Electrophysiology; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Ion Channels; Male; Microelectrodes; Neurons; Potassium Channels; Rats; Rats, Wistar; Synapses; Synaptic Transmission | 1993 |
Modulation of AMPA/kainate receptors by analogues of diazoxide and cyclothiazide in thin slices of rat hippocampus.
Topics: Action Potentials; Animals; Benzothiadiazines; Diazoxide; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Kainic Acid; Membrane Potentials; Molecular Structure; Rats; Receptors, AMPA; Receptors, Kainic Acid | 1993 |
Consequences of transient retinal hypoxia on rod input to horizontal cells in the rat retina.
Topics: Animals; Cell Hypoxia; Culture Techniques; Diazoxide; Glutamates; Glutamic Acid; Interneurons; Membrane Potentials; Photoreceptor Cells; Rats; Rats, Inbred Strains; Retina; Synapses; Synaptic Transmission | 1993 |
Arachidonic acid and oleoylacetylglycerol induce a synergistic facilitation of Ca(2+)-dependent glutamate release from hippocampal mossy fiber nerve endings.
Topics: 4-Aminopyridine; Action Potentials; Animals; Arachidonic Acid; Calcium; Calcium Channel Blockers; Cholinergic Agents; Cytochalasin D; Cytoskeleton; Diazoxide; Diglycerides; Drug Synergism; Excitatory Amino Acid Agents; Exocytosis; Glutamic Acid; Hippocampus; Ionomycin; Ionophores; Nerve Endings; Potassium; Protein Kinase C; Rats; Rats, Sprague-Dawley; Signal Transduction; Stimulation, Chemical; Synaptic Transmission | 1996 |
The diazoxide derivative IDRA 21 enhances ischemic hippocampal neuron injury.
Topics: Animals; Benzothiadiazines; Brain Ischemia; Cells, Cultured; Diazoxide; Diuretics; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Nerve Degeneration; Neurons; Neurotoxins; Quinoxalines; Rats; Rats, Inbred Strains; Receptors, AMPA; Sodium Chloride Symporter Inhibitors | 1998 |
Intrinsic optical signals in respiratory brain stem regions of mice: neurotransmitters, neuromodulators, and metabolic stress.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Adenosine Triphosphate; Animals; Animals, Newborn; Anti-Bacterial Agents; Antihypertensive Agents; Diazoxide; Energy Metabolism; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glyburide; Hypoglossal Nerve; Hypoglycemic Agents; Hypoxia; Kainic Acid; Macrolides; Mice; Mitochondrial Swelling; N-Methylaspartate; Optics and Photonics; Organ Culture Techniques; Ouabain; Potassium Channels; Respiratory Center; Sodium-Potassium-Exchanging ATPase; Tetrodotoxin | 2001 |
Opening of potassium channels modulates mitochondrial function in rat skeletal muscle.
Topics: Animals; Anti-Arrhythmia Agents; Cell Line; Cell Respiration; Diazoxide; Glutamic Acid; Glyburide; Malates; Membrane Potentials; Mitochondria, Muscle; Muscle, Skeletal; Myoblasts; Nicorandil; Oxidation-Reduction; Oxygen; Potassium Channels; Rats | 2002 |
Mitochondrial ATP-sensitive potassium channel: a novel site for neuroprotection.
Topics: Animals; Bradykinin; Cell Culture Techniques; Cell Survival; Cytoprotection; Decanoic Acids; Diazoxide; Glutamic Acid; Glyburide; Hydroxy Acids; Membrane Potentials; Membrane Proteins; Mitochondria; Molsidomine; Neurons; Neuroprotective Agents; Nitroprusside; Potassium Channels; Rats; Rats, Wistar; Retina | 2003 |
Mitochondrial ATP-sensitive potassium channel activation protects cerebellar granule neurons from apoptosis induced by oxidative stress.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Bongkrekic Acid; Caspase 3; Caspases; Cells, Cultured; Cerebellum; Cyclosporine; Diazoxide; Glutamic Acid; Ion Channels; Membrane Potentials; Microscopy, Confocal; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Neurons; Oxidants; Oxidative Stress; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Time Factors | 2003 |
Involvement of mitochondrial K+ release and cellular efflux in ischemic and apoptotic neuronal death.
Topics: Animals; Apoptosis; Brain Ischemia; Cell Death; Cell Hypoxia; Cells, Cultured; Cyanides; Decanoic Acids; Diazoxide; Disease Models, Animal; Enzyme Inhibitors; Fluorescent Dyes; Glutamic Acid; Hydroxy Acids; Male; Mice; Mice, Inbred C57BL; Mitochondria; Neurons; Neuroprotective Agents; Oxidative Stress; Potassium; Potassium Channel Blockers; Rats; Vasodilator Agents | 2003 |
Chemical preconditioning prevents paradoxical increase in glutamate release during ischemia by activating ATP-dependent potassium channels in gerbil hippocampus.
Topics: Adenosine Triphosphate; Animals; Brain Ischemia; Calcium; Diazoxide; Excitatory Postsynaptic Potentials; Gerbillinae; Glutamic Acid; Glyburide; Hippocampus; In Vitro Techniques; Neurotoxins; Nitro Compounds; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Propionates | 2003 |
Diazoxide preconditioning protects against neuronal cell death by attenuation of oxidative stress upon glutamate stimulation.
Topics: Analysis of Variance; Animals; Blotting, Western; Carrier Proteins; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Diazoxide; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Female; Glutamic Acid; Male; Neurons; Neuroprotective Agents; Oxidative Stress; Peroxidases; Peroxiredoxins; Pregnancy; Rats; Rats, Wistar; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Superoxides; Time Factors | 2004 |
Effects of KATP channel modulation on myocardial glycogen content, lactate, and amino acids in nonischemic and ischemic rat hearts.
Topics: Alanine; Amino Acids; Animals; Diazoxide; Drug Interactions; Glutamic Acid; Glyburide; Glycogen; Lactic Acid; Male; Myocardial Ischemia; Myocardium; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar | 2005 |
Iptakalim protects PC12 cell against H2O2-induced oxidative injury via opening mitochondrial ATP-sensitive potassium channel.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Biological Transport; Calcium; Cell Survival; Diazoxide; Glutamic Acid; Hydrogen Peroxide; Mitochondrial Proteins; Neurons; Neuroprotective Agents; Oxidative Stress; PC12 Cells; Potassium Channels; Propylamines; Rats | 2006 |
Diazoxide is protective in the rat retina against ischemic injury induced by bilateral carotid occlusion and glutamate-induced degeneration.
Topics: Animals; Animals, Newborn; Cell Count; Diazoxide; Disease Models, Animal; Drug Interactions; Glutamic Acid; Myocardial Ischemia; Neuroprotective Agents; Rats; Rats, Wistar; Retinal Diseases | 2007 |