diazoxide has been researched along with cyclosporine in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.00) | 18.2507 |
| 2000's | 15 (60.00) | 29.6817 |
| 2010's | 9 (36.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Holmuhamedov, EL; Terzic, A; Wang, L | 1 |
| Berggren, PO; Bokvist, K; Buschard, K; Gromada, J; Hansen, J; Høy, M; Juhl, K; Xiao-Gang, W | 1 |
| Hayashi, H; Katoh, H; Nishigaki, N | 1 |
| Baxter, GF; Hausenloy, DJ; Maddock, HL; Yellon, DM | 1 |
| Akao, M; Jones, SP; Kusuoka, H; Marbán, E; O'Rourke, B; Teshima, Y | 1 |
| Akao, M; Baumgartner, WA; Chong, TH; Johnston, MV; Li, RA; Marbán, E; Teshima, Y | 1 |
| Duchen, M; Hausenloy, D; Wynne, A; Yellon, D | 1 |
| Ishida, H | 1 |
| Halestrap, AP | 1 |
| Bruce, IC; Lin, L; Shen, F; Wu, L; Xia, Q; Zhang, X | 1 |
| Davidson, SM; Hausenloy, DJ; Lim, SY; Yellon, DM | 1 |
| Mozaffari, MS; Schaffer, SW | 1 |
| Gao, J; Jiang, L; Li, J; Liu, K; Ma, G; Tan, S; Wang, T; Zeng, X; Zhang, Y | 1 |
| Hansson, MJ; Morota, S; Piel, S | 1 |
| Bu, HM; Ma, HJ; Sun, H; Wang, ML; Yang, CY; Zhang, Y | 1 |
2 review(s) available for diazoxide and cyclosporine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[The research method for investigating the role of the mitochondrial permeability transition pore in cell death].
Topics: Apoptosis; Arsenicals; Calcium; Cyclosporine; Cytochromes c; Diazoxide; Humans; Ion Channels; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Reperfusion Injury; Myocardium; Necrosis; Ouabain | 2004 |
23 other study(ies) available for diazoxide and cyclosporine
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
ATP-sensitive K+ channel openers prevent Ca2+ overload in rat cardiac mitochondria.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cyclosporine; Diazoxide; In Vitro Techniques; Ionophores; Membrane Potentials; Membrane Proteins; Microscopy, Confocal; Mitochondria, Heart; Myocardium; Oxygen Consumption; Permeability; Pinacidil; Potassium Channels; Rats; Rats, Sprague-Dawley; Valinomycin | 1999 |
Phentolamine inhibits exocytosis of glucagon by Gi2 protein-dependent activation of calcineurin in rat pancreatic alpha -cells.
Topics: Adenylate Cyclase Toxin; Animals; Calcineurin; Cells, Cultured; Clorgyline; Cyclosporine; Cystamine; Diazoxide; Exocytosis; Glucagon; GTP-Binding Protein alpha Subunit, Gi2; GTP-Binding Protein alpha Subunits, Gi-Go; Imidazoles; Indoles; Islets of Langerhans; Male; Membrane Potentials; Nitriles; Oligodeoxyribonucleotides, Antisense; Pertussis Toxin; Phentolamine; Potassium Channels; Proto-Oncogene Proteins; Pyrethrins; Rats; Rats, Inbred Lew; Virulence Factors, Bordetella | 2001 |
Diazoxide opens the mitochondrial permeability transition pore and alters Ca2+ transients in rat ventricular myocytes.
Topics: Animals; Antihypertensive Agents; Calcium; Calcium Signaling; Cyclosporine; Diazoxide; Enzyme Inhibitors; Flavoproteins; Fluoresceins; Fluorescent Dyes; Heart Ventricles; In Vitro Techniques; Intracellular Membranes; Ion Channels; Membrane Potentials; Microscopy, Confocal; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardium; Oxidation-Reduction; Rats | 2002 |
Inhibiting mitochondrial permeability transition pore opening: a new paradigm for myocardial preconditioning?
Topics: Adenosine; Analysis of Variance; Animals; Atractyloside; Calcineurin Inhibitors; Cyclosporine; Decanoic Acids; Diazoxide; Enzyme Inhibitors; Hydroxy Acids; Ion Channels; Ischemic Preconditioning, Myocardial; Male; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Ischemia; Myocardial Reperfusion Injury; Perfusion; Permeability; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Purinergic P1 Receptor Agonists; Random Allocation; Rats; Rats, Sprague-Dawley; Tacrolimus | 2002 |
Differential actions of cardioprotective agents on the mitochondrial death pathway.
Topics: Bongkrekic Acid; Cardiotonic Agents; Cell Death; Cyclosporine; Diazoxide; Enzyme Inhibitors; Ion Channels; Membrane Potentials; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Potassium Channel Blockers; Potassium Channels; Signal Transduction | 2003 |
Mitochondrial ATP-sensitive potassium channel activation protects cerebellar granule neurons from apoptosis induced by oxidative stress.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Bongkrekic Acid; Caspase 3; Caspases; Cells, Cultured; Cerebellum; Cyclosporine; Diazoxide; Glutamic Acid; Ion Channels; Membrane Potentials; Microscopy, Confocal; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Neurons; Oxidants; Oxidative Stress; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Time Factors | 2003 |
Transient mitochondrial permeability transition pore opening mediates preconditioning-induced protection.
Topics: 2,4-Dinitrophenol; Adenosine; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Cardiotonic Agents; Cells, Cultured; Cyclosporine; Diazoxide; Electric Conductivity; Ion Channel Gating; Ion Channels; Ion Transport; Ischemic Preconditioning, Myocardial; Lactones; Macromolecular Substances; Male; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidative Phosphorylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Spiro Compounds; Uncoupling Agents; Vasodilator Agents | 2004 |
Does the mitochondrial permeability transition have a role in preconditioning?
Topics: Calcium; Cyclosporine; Diazoxide; Humans; Ion Channels; Ischemic Preconditioning; Lactones; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Models, Biological; Oxidative Stress; Spiro Compounds; Uncoupling Agents | 2004 |
The neuroprotection conferred by activating the mitochondrial ATP-sensitive K+ channel is mediated by inhibiting the mitochondrial permeability transition pore.
Topics: Animals; Atractyloside; Brain Infarction; Cyclosporine; Diazoxide; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Infarction, Middle Cerebral Artery; Male; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Neuroprotective Agents; Potassium Channels; Rats; Rats, Sprague-Dawley; Reperfusion; Time Factors | 2006 |
Preconditioning and postconditioning: the essential role of the mitochondrial permeability transition pore.
Topics: Animals; Bradykinin; Cyclophilins; Cyclosporine; Diazoxide; Enzyme Inhibitors; Female; Ischemic Preconditioning, Myocardial; Lactones; Male; Mice; Mice, Knockout; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Models, Animal; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Peptidyl-Prolyl Isomerase F; Spiro Compounds; Vasodilator Agents | 2007 |
Effect of pressure overload on cardioprotection of mitochondrial KATP channels and GSK-3beta: interaction with the MPT pore.
Topics: Animals; Cardiotonic Agents; Cyclosporine; Diazoxide; Disease Models, Animal; Glyburide; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hypertension; In Vitro Techniques; Indoles; Lithium Chloride; Male; Maleimides; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Perfusion; Potassium Channel Blockers; Potassium Channels; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Ventricular Function, Left; Ventricular Pressure | 2008 |
Diazoxide and cyclosporin A protect primary cholinergic neurons against beta-amyloid (1-42)-induced cytotoxicity.
Topics: Amyloid beta-Peptides; Animals; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Cell Survival; Cholinergic Neurons; Cyclosporine; Diazoxide; Drug Synergism; Gene Expression; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Neuroprotective Agents; Peptide Fragments; Potassium Channels; Primary Cell Culture; Prosencephalon; Rats | 2013 |
Respiratory uncoupling by increased H(+) or K(+) flux is beneficial for heart mitochondrial turnover of reactive oxygen species but not for permeability transition.
Topics: Animals; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cations, Monovalent; Cyclosporine; Diazoxide; Hydrogen Peroxide; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitochondrial Swelling; Osmolar Concentration; Oxidative Phosphorylation; Oxygen; Permeability; Potassium; Potassium Channels; Proton Ionophores; Protons; Rats; Reactive Oxygen Species; Uncoupling Agents; Valinomycin | 2013 |
K(ATP) channels and MPTP are involved in the cardioprotection bestowed by chronic intermittent hypobaric hypoxia in the developing rat.
Topics: Animals; Atmospheric Pressure; Atractyloside; Cardiotonic Agents; Cyclosporine; Decanoic Acids; Diazoxide; Glyburide; Hydroxy Acids; Hypoxia; Male; Microscopy, Electron, Transmission; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Reperfusion Injury; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2015 |