diazoxide has been researched along with caffeine in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (32.00) | 18.7374 |
| 1990's | 5 (20.00) | 18.2507 |
| 2000's | 6 (24.00) | 29.6817 |
| 2010's | 6 (24.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Branch, RA; Brown, NJ; Porter, J; Ryder, D | 1 |
| Cook, JR; Montague, W | 1 |
| Haist, RE; Lin, BJ | 1 |
| Porte, D; Robertson, RP | 1 |
| Howell, SL; Montague, W | 1 |
| Butter, R; Fiedler, H; Hahn, HJ; Henkel, M; Ziegler, B; Ziegler, M | 1 |
| Marks, V | 1 |
| De la Tour, J; Debray, C; Roze, C; Souchard, M; Vaille, C | 1 |
| Li, G; Pralong, WF; Wollheim, CB | 1 |
| Dessy, C; Godfraind, T | 1 |
| Grapengiesser, E; Gylfe, E; Hellman, B; Liu, YJ | 1 |
| Bánhegyi, G; Benedetti, A; Fulceri, R; Gamberucci, A; Marcolongo, P; Pralong, W; Watkins, SL | 1 |
| Kamishima, T; Quayle, JM | 1 |
2 review(s) available for diazoxide and caffeine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Control of insulin secretion by catecholamines, stress, and the sympathetic nervous system.
Topics: Animals; Caffeine; Catecholamines; Cyclic AMP; Diazoxide; Epinephrine; Glucose; Hypothermia; Hypoxia; Insulin; Insulin Secretion; Islets of Langerhans; Pancreas; Phentolamine; Propranolol; Receptors, Adrenergic; Stress, Physiological; Sympathetic Nervous System; Theophylline | 1973 |
1 trial(s) available for diazoxide and caffeine
| Article | Year |
|---|---|
Caffeine potentiates the renin response to diazoxide in man. Evidence for a regulatory role of endogenous adenosine.
Topics: Adenosine; Adult; Blood Pressure; Caffeine; Catecholamines; Diazoxide; Drug Synergism; Drug Tolerance; Female; Humans; Infusions, Intravenous; Male; Pulse; Purinergic Antagonists; Renin; Time Factors | 1991 |
22 other study(ies) available for diazoxide and caffeine
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
The role of adenosine 3':5'-cyclic monophosphate in the regulation of insulin release by isolated rat islets of Langerhans.
Topics: Animals; Caffeine; Cyclic AMP; Diazoxide; Epinephrine; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Rats; Theophylline; Xanthines | 1971 |
Effects of some modifiers of insulin secretion on insulin biosynthesis.
Topics: Animals; Caffeine; Calcium; Citrates; Cyclic AMP; Diazoxide; Drug Synergism; Electrophoresis, Polyacrylamide Gel; Epinephrine; Glucose; In Vitro Techniques; Insulin; Islets of Langerhans; Magnesium; Male; Proinsulin; Rats; Tritium | 1973 |
The mode of action of adenosine 3':5'-cyclic monophosphate in mammalian islets of Langerhans. Effects of insulin secretagogues on islet-cell protein kinase activity.
Topics: Animals; Arginine; Caffeine; Cyclic AMP; Diazoxide; Epinephrine; Glucagon; Glyburide; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Phosphorus Isotopes; Phosphotransferases; Protein Kinases; Rats; Theophylline; Time Factors; Tolbutamide; Xanthines; Xylitol | 1973 |
[Islands of Langerhans in vitro. VII. Comparative studies on insulin secretion stimulation by various substrates in the rat].
Topics: Animals; Arginine; Bucladesine; Caffeine; Calcium; Diazoxide; Glucose; Glyburide; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Radioimmunoassay; Rats; Time Factors; Xylitol | 1973 |
Effect of drugs on carbohydrate metabolism.
Topics: Adult; Blood Glucose; Caffeine; Carbohydrate Metabolism; Carbohydrate Metabolism, Inborn Errors; Child; Diazoxide; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Ethanol; Glucose; Humans; Hyperglycemia; Hypoglycemia; Metabolic Diseases; Nicotinic Acids; Sulfonylurea Compounds | 1974 |
[Glycemia modifiers, carbonated soda water and external pancreatic secretion in rats].
Topics: Animals; Blood Glucose; Caffeine; Diazoxide; Glucagon; Insulin; Mineral Waters; Pancreatic Juice; Rats; Stimulation, Chemical | 1969 |
Oscillations of cytosolic free calcium in bombesin-stimulated HIT-T15 cells.
Topics: Animals; Biological Clocks; Bombesin; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium-Transporting ATPases; Cell Line; Central Nervous System Stimulants; Chelating Agents; Circadian Rhythm; Cresols; Cricetinae; Cytosol; Diazoxide; Egtazic Acid; Fura-2; Glucose; Hydroquinones; Membrane Potentials; Ryanodine; Verapamil | 1996 |
The effect of L-type calcium channel modulators on the mobilization of intracellular calcium stores in guinea-pig intestinal smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Diazoxide; Fura-2; Guinea Pigs; Histamine; Ileum; Isometric Contraction; Muscle, Smooth; Nimodipine; Ryanodine; Thapsigargin | 1996 |
Crosstalk between the cAMP and inositol trisphosphate-signalling pathways in pancreatic beta-cells.
Topics: Animals; Caffeine; Calcium; Cells, Cultured; Cyclic AMP; Cytosol; Diazoxide; Gallopamil; Glucagon; Glucose; Inositol 1,4,5-Trisphosphate; Islets of Langerhans; Kinetics; Membrane Potentials; Mice; Mice, Obese; Oscillometry; Potassium; Ryanodine; Signal Transduction; Strontium; Tetradecanoylphorbol Acetate | 1996 |
Caffeine releases a glucose-primed endoplasmic reticulum Ca2+ pool in the insulin secreting cell line INS-1.
Topics: Animals; Caffeine; Calcium; Carbachol; Cell Line; Diazoxide; Electrophysiology; Endoplasmic Reticulum; Glucose; Insulin; Rabbits; Thapsigargin | 1999 |
Mitochondrial Ca2+ uptake is important over low [Ca2+]i range in arterial smooth muscle.
Topics: Animals; Caffeine; Calcium; Calcium Signaling; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Separation; Diazoxide; Femoral Artery; In Vitro Techniques; Intracellular Fluid; Intracellular Membranes; Male; Membrane Potentials; Mitochondria, Muscle; Muscle, Smooth, Vascular; Patch-Clamp Techniques; Rats; Uncoupling Agents | 2002 |