Compounds > diazoxide

diazoxide and bpdz 44

diazoxide has been researched along with bpdz 44 in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (72.73)18.2507
2000's3 (27.27)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Antoine, MH; de Tullio, P; Delarge, J; Dupont, L; Fontaine, J; Herchuelz, A; Lebrun, P; Masereel, B; Pirotte, B; Schynts, M1
Antoine, MH; de Tullio, P; Delarge, J; Diouf, O; Dupont, L; Fontaine, J; Khelili, S; Lebrun, P; Maggetto, C; Masereel, B; Ouedraogo, R; Pirotte, B; Podona, T1
de Tullio, P; Delarge, J; Diouf, O; Dupont, L; Lebrun, P; Lepagnol, J; Lestage, P; Morain, P; Pirotte, B; Podona, T; Somers, F; Spedding, M1
Boverie, S; Damas, J; de Tullio, P; Dupont, L; Fontaine, J; Khelili, S; Lebrun, P; Ouedraogo, R; Pirotte, B; Somers, F1
Antoine, MH; Becker, B; Damas, J; de Tullio, P; Delarge, J; Dupont, L; Fontaine, J; Lebrun, P; Ouedraogo, R; Pirotte, B; Rigo, B; Somers, F1
Antoine, MH; Becker, B; Boverie, S; Counerotte, S; de Tullio, P; Lebrun, P; Ouedraogo, R; Pirotte, B; Sebille, S; Somers, F1
Antoine, MH; de Tullio, P; Delarge, J; Herchuelz, A; Hermann, M; Lebrun, P; Pirotte, B1
Francini, F; Gagliardino, JJ; Pirotte, B1
Aynsley-Green, A; Dunne, MJ; James, RF; Johnson, PR; Kane, C; Lindley, KJ; Milla, PJ1
Albert, A; De Tullio, P; Delarge, J; Dresse, A; Massotte, L; Pirotte, B; Scuvée-Moreau, J; Seutin, V; Vrijens, B1
Antoine, MH; de Tullio, P; Delarge, J; Herchuelz, A; Lebrun, P; Ouedraogo, R; Pirotte, B1

Other Studies

11 other study(ies) available for diazoxide and bpdz 44

ArticleYear
3-(Alkylamino)-4H-pyrido[4,3-e]-1,2,4-thiadiazine 1,1-dioxides as powerful inhibitors of insulin release from rat pancreatic B-cells: a new class of potassium channel openers?
    Journal of medicinal chemistry, 1993, Oct-15, Volume: 36, Issue:21

    Topics: Animals; Insulin; Insulin Secretion; Islets of Langerhans; Potassium Channels; Pyridines; Rats; Structure-Activity Relationship; Thiadiazines

1993
3-and 4-substituted 4H-pyrido[4,3-e]-1,2,4-thiadiazine 1,1-dioxides as potassium channel openers: synthesis, pharmacological evaluation, and structure-activity relationships.
    Journal of medicinal chemistry, 1996, Feb-16, Volume: 39, Issue:4

    Topics: Animals; Aorta; Diazoxide; Female; Guinea Pigs; Ileum; In Vitro Techniques; Indicators and Reagents; Insulin; Insulin Secretion; Islets of Langerhans; Male; Models, Molecular; Molecular Conformation; Molecular Structure; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Myocardial Contraction; Potassium Channels; Rats; Rats, Wistar; Structure-Activity Relationship; Thiadiazines; Vasodilator Agents

1996
4H-1,2,4-Pyridothiadiazine 1,1-dioxides and 2,3-dihydro-4H-1,2, 4-pyridothiadiazine 1,1-dioxides chemically related to diazoxide and cyclothiazide as powerful positive allosteric modulators of (R/S)-2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic aci
    Journal of medicinal chemistry, 1998, Jul-30, Volume: 41, Issue:16

    Topics: Adenosine Triphosphate; Allosteric Regulation; Animals; Benzothiadiazines; Cerebral Cortex; Cyclic S-Oxides; Diazoxide; Drug Design; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Insulin; Insulin Antagonists; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred DBA; Oocytes; Potassium Channels; Rats; Rats, Wistar; Receptors, AMPA; RNA, Messenger; Solubility; Stereoisomerism; Structure-Activity Relationship; Thiadiazines; Xenopus laevis

1998
3-Alkylamino-4H-pyrido[2,3-e]-1,2,4-thiadiazine 1,1-dioxides structurally related to diazoxide and pinacidil as potassium channel openers acting on vascular smooth muscle cells: design, synthesis, and pharmacological evaluation.
    Journal of medicinal chemistry, 2000, Apr-20, Volume: 43, Issue:8

    Topics: Animals; Aorta; Cyclic S-Oxides; Diazoxide; Drug Design; Female; Guinea Pigs; Ileum; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Muscle Contraction; Muscle, Smooth, Vascular; Pinacidil; Potassium Channels; Rats; Rats, Wistar; Structure-Activity Relationship; Thiadiazines; Uterine Contraction; Vasodilator Agents

2000
Original 2-alkylamino-6-halogenoquinazolin-4(3H)-ones and K(ATP) channel activity.
    Journal of medicinal chemistry, 2001, Aug-02, Volume: 44, Issue:16

    Topics: Adenosine Triphosphate; Animals; Aorta; Calcium; Crystallography, X-Ray; Female; Glyburide; Guinea Pigs; Ileum; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Muscle Contraction; Muscle, Smooth; Potassium Channels; Potassium Chloride; Quinazolines; Rats; Rats, Wistar; Rubidium; Structure-Activity Relationship; Uterine Contraction; Uterus

2001
Effect on K(ATP) channel activation properties and tissue selectivity of the nature of the substituent in the 7- and the 3-position of 4H-1,2,4-benzothiadiazine 1,1-dioxides.
    Journal of medicinal chemistry, 2005, May-19, Volume: 48, Issue:10

    Topics: Adenosine Triphosphate; Animals; Aorta; Benzothiadiazines; In Vitro Techniques; Insulin; Insulin Secretion; Ion Channel Gating; Islets of Langerhans; Muscle Contraction; Muscle, Smooth, Vascular; Potassium Channels; Rats; Rats, Wistar; Structure-Activity Relationship; Vasodilator Agents

2005
Cationic and secretory effects of BPDZ 44 and diazoxide in rat pancreatic islets.
    Experientia, 1994, Sep-15, Volume: 50, Issue:9

    Topics: Animals; Calcium Radioisotopes; Cations; Diazoxide; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Pyridines; Rats; Rubidium Radioisotopes; Thiadiazines

1994
Effect of activators and inhibitors of K+ channels on insulin secretion in the amphibian pancreas.
    Archives of physiology and biochemistry, 1997, Volume: 105, Issue:1

    Topics: Animals; Antihypertensive Agents; Bufo arenarum; Calcium Channels; Clonidine; Diazoxide; Galactose; Glucose; Glyceraldehyde; Hormone Antagonists; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Male; Potassium Channel Blockers; Potassium Channels; Pyridines; Radioimmunoassay; Somatostatin; Tetraethylammonium; Tetraethylammonium Compounds; Thiadiazines; Tolbutamide

1997
Therapy for persistent hyperinsulinemic hypoglycemia of infancy. Understanding the responsiveness of beta cells to diazoxide and somatostatin.
    The Journal of clinical investigation, 1997, Oct-01, Volume: 100, Issue:7

    Topics: Blood Glucose; Cell Membrane; Diazoxide; Disease Management; Electrophysiology; Glycosyltransferases; Humans; Hydrochlorothiazide; Hyperinsulinism; Hypoglycemia; Infant, Newborn; Islets of Langerhans; Membrane Proteins; Octreotide; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pyridines; Repressor Proteins; Saccharomyces cerevisiae Proteins; Somatostatin; Thiadiazines

1997
Effect of potassium channel openers on the firing rate of hippocampal pyramidal cells and A10 dopaminergic neurons in vitro.
    Archives of physiology and biochemistry, 1997, Volume: 105, Issue:5

    Topics: Action Potentials; Animals; Cromakalim; Diazoxide; Dopamine; Guanidines; Hippocampus; In Vitro Techniques; Male; Neurons; Pinacidil; Potassium Channels; Pyramidal Cells; Pyridines; Rats; Rats, Wistar; Thiadiazines; Ventral Tegmental Area

1997
Pyridothiadiazines as potent inhibitors of glucose-induced insulin release.
    Advances in experimental medicine and biology, 1997, Volume: 426

    Topics: Animals; Calcium; Cytosol; Diazoxide; Glucose; Guanidines; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Pinacidil; Pyridines; Rats; Rubidium; Structure-Activity Relationship; Thiadiazines; Time Factors

1997