diazoxide and adenosine

diazoxide has been researched along with adenosine in 31 studies

Research

Studies (31)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	4 (12.90)	18.2507
2000's	24 (77.42)	29.6817
2010's	3 (9.68)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Branch, RA; Brown, NJ; Porter, J; Ryder, D	1
Gäbel, J; Lebrun, P; Malaisse, WJ; Pirotte, B; Rorsman, P; Valverde, I; Van Poelje, PD; Villanueva-Peñacarrillo, ML; Viñambres, C	1
Hashimoto, K; Kano, M	1
Foldes, FF; Matkó, I; Nagashima, H; Oe, K; Sántha, E; Sperlágh, B; Vizi, ES	1
Banerjee, A; Harken, AH; Heimbach, JK; Morrell, TD; Pomerantz, BJ; Robinson, TN	1
Marbán, E; O'Rourke, B; Sasaki, N; Sato, T	1
Haller, M; Mironov, SL; Richter, DW	1
Latchman, DS; Schulman, D; Yellon, DM	1
Lacerda, L; McCarthy, J; Meiring, JJ; Minners, J; Sack, MN; Yellon, DM	1
Baxter, GF; Hausenloy, DJ; Maddock, HL; Yellon, DM	1
McCarthy, J; Sack, MN; Smith, RM; Suleman, N	1
Pei, GX; Wang, G; Wang, HM; Wang, QL	1
Headrick, JP; Peart, J; Willems, L	1
Ashton, KJ; Headrick, JP; Holmgren, K; Matherne, GP; Peart, J; Willems, L	1
Headrick, JP; Peart, J	1
Imamura, H; Kido, M; Nakao, S; Ninomiya, H; Okada, T; Otani, H; Shingu, K; Uchiyama, T; Uchiyama, Y	1
Abrahani, A; Brownsey, R; Cheung, C; Ghosh, S; Pulinilkunnil, T; Qi, D; Rodrigues, B; Varghese, J; Yip, P	1
Levitsky, S; McCully, JD	1
O'Rourke, B	1
Duchen, M; Hausenloy, D; Wynne, A; Yellon, D	1
Imamura, H; Nakao, S; Otani, H; Shingu, K; Uchiyama, Y; Wakeno-Takahashi, M	1
Fujiwara, H; Hattori, R; Imamura, H; Kyoi, S; Okada, T; Otani, H; Sumida, T; Uchiyama, T; Wu, Y	1
Borne, J; Frame, MD; Mabanta, L; Valane, P	1
Fowler, A; Galiñanes, M; Hassouna, A; Loubani, M; Matata, BM; Standen, NB	1
Amanpour, S; Beheshtian, A; Dehpour, AR; Demehri, S; Ghazinezami, B; Kiumehr, S; Mohagheghi, MA; Nezami, BG; Rabbani, S; Rahimpour, S; Salmasi, AH	1
Arrell, DK; Elliott, ST; Guo, Y; Kane, LA; Ko, YH; Marbán, E; Murata, M; Murphy, AM; Pedersen, PL; Robinson, J; Van Eyk, JE	1
El-Ani, D; Mashiach, Y; Shainberg, A; Zimlichman, R	1
Brennan, S; Hudman, D; Jackson, R; Lodwick, D; Norman, RI; Patel, M; Rainbow, RD; Sims, MW	1

Reviews

3 review(s) available for diazoxide and adenosine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Mitochondrial ATP-sensitive potassium channels in surgical cardioprotection. Archives of biochemistry and biophysics, 2003, Dec-15, Volume: 420, Issue:2 Topics: Adenosine; Adenosine Triphosphate; Animals; Cardiotonic Agents; Diazoxide; Disease Models, Animal; Heart Arrest, Induced; Humans; Ischemic Preconditioning, Myocardial; Mitochondria, Heart; Myocardial Ischemia; Myocardial Reperfusion Injury; Potassium Channel Blockers; Potassium Channels; Sarcolemma	2003
Evidence for mitochondrial K+ channels and their role in cardioprotection. Circulation research, 2004, Mar-05, Volume: 94, Issue:4 Topics: Adenosine; Animals; Cattle; Diazoxide; Energy Metabolism; Humans; Ion Transport; Ischemic Preconditioning, Myocardial; Membrane Proteins; Mice; Mitochondria, Heart; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidation-Reduction; Oxidative Phosphorylation; Patch-Clamp Techniques; Potassium; Potassium Channels; Rats	2004

Trials

1 trial(s) available for diazoxide and adenosine

Article	Year
Caffeine potentiates the renin response to diazoxide in man. Evidence for a regulatory role of endogenous adenosine. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:1 Topics: Adenosine; Adult; Blood Pressure; Caffeine; Catecholamines; Diazoxide; Drug Synergism; Drug Tolerance; Female; Humans; Infusions, Intravenous; Male; Pulse; Purinergic Antagonists; Renin; Time Factors	1991

Article

Year

Caffeine potentiates the renin response to diazoxide in man. Evidence for a regulatory role of endogenous adenosine.

The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:1

Topics: Adenosine; Adult; Blood Pressure; Caffeine; Catecholamines; Diazoxide; Drug Synergism; Drug Tolerance; Female; Humans; Infusions, Intravenous; Male; Pulse; Purinergic Antagonists; Renin; Time Factors

1991

Other Studies

27 other study(ies) available for diazoxide and adenosine

Article	Year
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
The riddle of formycin A insulinotropic action. Biochemical and molecular medicine, 1996, Volume: 57, Issue:1 Topics: Adenosine; Animals; Calcium; Diabetes Mellitus, Type 2; Diazoxide; Female; Formycins; Glucose; Glyburide; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Rats; Ribonucleotides; Tubercidin; Verapamil; Xanthines	1996
Presynaptic origin of paired-pulse depression at climbing fibre-Purkinje cell synapses in the rat cerebellum. The Journal of physiology, 1998, Jan-15, Volume: 506 ( Pt 2) Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adenosine; Afferent Pathways; Animals; Baclofen; Calcium; Cerebellum; Diazoxide; Electric Conductivity; Electric Stimulation; Electrophysiology; Evoked Potentials; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Extracellular Space; GABA Agonists; GABA Antagonists; Nerve Fibers; Neurons; Neurotransmitter Agents; Pipecolic Acids; Presynaptic Terminals; Purinergic P1 Receptor Antagonists; Purkinje Cells; Rats; Rats, Wistar; Receptors, AMPA; Receptors, GABA-B; Receptors, Glutamate; Synapses; Synaptic Transmission; Vasodilator Agents	1998
Modulation of norepinephrine release by ATP-dependent K(+)-channel activators and inhibitors in guinea-pig and human isolated right atrium. Cardiovascular research, 1999, Volume: 43, Issue:1 Topics: Adenosine; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Analysis of Variance; Animals; Clonidine; Cromakalim; Decanoic Acids; Diazoxide; Dose-Response Relationship, Drug; Glyburide; Guinea Pigs; Heart Atria; Humans; Hydroxy Acids; In Vitro Techniques; Male; Muscarinic Agonists; Norepinephrine; Oxotremorine; Pinacidil; Potassium Channel Blockers; Potassium Channels; Stimulation, Chemical; Sympathetic Nervous System	1999
Selective mitochondrial adenosine triphosphate-sensitive potassium channel activation is sufficient to precondition human myocardium. The Journal of thoracic and cardiovascular surgery, 2000, Volume: 120, Issue:2 Topics: Adenosine; Adenosine Triphosphate; Analysis of Variance; Creatine Kinase; Diazoxide; Humans; Mitochondria, Heart; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Potassium Channels; Vasodilator Agents	2000
Adenosine primes the opening of mitochondrial ATP-sensitive potassium channels: a key step in ischemic preconditioning? Circulation, 2000, Aug-15, Volume: 102, Issue:7 Topics: Adenosine; Animals; Decanoic Acids; Diazoxide; Enzyme Inhibitors; Flavoproteins; Hydroxy Acids; Ischemic Preconditioning; Membrane Proteins; Oxidation-Reduction; Polymyxin B; Potassium Channels; Protein Kinase C; Purinergic P1 Receptor Antagonists; Rabbits; Theophylline; Time Factors	2000
Intrinsic optical signals in respiratory brain stem regions of mice: neurotransmitters, neuromodulators, and metabolic stress. Journal of neurophysiology, 2001, Volume: 86, Issue:1 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Adenosine Triphosphate; Animals; Animals, Newborn; Anti-Bacterial Agents; Antihypertensive Agents; Diazoxide; Energy Metabolism; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glyburide; Hypoglossal Nerve; Hypoglycemic Agents; Hypoxia; Kainic Acid; Macrolides; Mice; Mitochondrial Swelling; N-Methylaspartate; Optics and Photonics; Organ Culture Techniques; Ouabain; Potassium Channels; Respiratory Center; Sodium-Potassium-Exchanging ATPase; Tetrodotoxin	2001
Effect of aging on the ability of preconditioning to protect rat hearts from ischemia-reperfusion injury. American journal of physiology. Heart and circulatory physiology, 2001, Volume: 281, Issue:4 Topics: Adenosine; Aging; Animals; Diazoxide; Diglycerides; Heart; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Time Factors; Vasodilator Agents	2001
Ischemic and pharmacological preconditioning in Girardi cells and C2C12 myotubes induce mitochondrial uncoupling. Circulation research, 2001, Oct-26, Volume: 89, Issue:9 Topics: Adenosine; Adenosine Triphosphate; Animals; Cell Line, Transformed; Cell Survival; Decanoic Acids; Diazoxide; Flow Cytometry; Humans; Hydroxy Acids; Intracellular Membranes; Ischemic Preconditioning, Myocardial; L-Lactate Dehydrogenase; Membrane Potentials; Mice; Mitochondria; Muscle, Skeletal; Oxygen Consumption; Vasodilator Agents	2001
Inhibiting mitochondrial permeability transition pore opening: a new paradigm for myocardial preconditioning? Cardiovascular research, 2002, Aug-15, Volume: 55, Issue:3 Topics: Adenosine; Analysis of Variance; Animals; Atractyloside; Calcineurin Inhibitors; Cyclosporine; Decanoic Acids; Diazoxide; Enzyme Inhibitors; Hydroxy Acids; Ion Channels; Ischemic Preconditioning, Myocardial; Male; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Ischemia; Myocardial Reperfusion Injury; Perfusion; Permeability; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Purinergic P1 Receptor Agonists; Random Allocation; Rats; Rats, Sprague-Dawley; Tacrolimus	2002
Classic ischemic but not pharmacologic preconditioning is abrogated following genetic ablation of the TNFalpha gene. Cardiovascular research, 2002, Aug-15, Volume: 55, Issue:3 Topics: Adenosine; Analysis of Variance; Animals; Decanoic Acids; Diazoxide; Hydroxy Acids; Ischemic Preconditioning, Myocardial; Male; Mice; Mice, Knockout; Myocardial Infarction; Myocardium; Perfusion; Potassium Channel Blockers; Potassium Channels; Recombinant Proteins; Tumor Necrosis Factor-alpha	2002
Effect of pretreatment with adenosine, diazoxide or ischemic preconditioning on ischemia- reperfusion injury in the limbs of rats. Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 2002, Volume: 22, Issue:7 Topics: Adenosine; Animals; Creatine Kinase; Diazoxide; Disease Models, Animal; Extremities; Ischemic Preconditioning; Male; Protective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury	2002
Receptor and non-receptor-dependent mechanisms of cardioprotection with adenosine. American journal of physiology. Heart and circulatory physiology, 2003, Volume: 284, Issue:2 Topics: Adenosine; Adenosine Kinase; Adenosine Triphosphate; Animals; Cardiotonic Agents; Diazoxide; Drug Administration Schedule; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mitochondria, Heart; Myocardial Ischemia; Myocardial Reperfusion Injury; Potassium Channels; Protein Kinase C; Purinergic P1 Receptor Agonists; Recovery of Function	2003
Ischaemic tolerance in aged mouse myocardium: the role of adenosine and effects of A1 adenosine receptor overexpression. The Journal of physiology, 2003, Jun-15, Volume: 549, Issue:Pt 3 Topics: Adenosine; Adenosine A1 Receptor Antagonists; Aging; Alkaloids; Animals; Arrhythmias, Cardiac; Benzophenanthridines; Coronary Circulation; Decanoic Acids; Diazoxide; DNA Primers; Female; Gene Expression; Heart; Hydroxy Acids; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Mice; Mice, Inbred C57BL; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Organ Size; Phenanthridines; Receptor, Adenosine A1; Vasodilator Agents	2003
Adenosine-mediated early preconditioning in mouse: protective signaling and concentration dependent effects. Cardiovascular research, 2003, Jun-01, Volume: 58, Issue:3 Topics: Adenosine; Adenosine Diphosphate; Alkaloids; Animals; Benzophenanthridines; Calcium Channel Blockers; Decanoic Acids; Diazoxide; Enzyme Inhibitors; Hydroxy Acids; Hypoxanthine; Inosine; Ischemic Preconditioning, Myocardial; L-Lactate Dehydrogenase; Male; Mice; Mice, Inbred C57BL; Mitochondria, Heart; Myocardial Contraction; Myocardial Infarction; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Perfusion; Phenanthridines; Phenethylamines; Potassium Channels; Protein Kinase C; Receptors, Purinergic P2; Signal Transduction; Xanthine	2003
Integrated pharmacological preconditioning in combination with adenosine, a mitochondrial KATP channel opener and a nitric oxide donor. The Journal of thoracic and cardiovascular surgery, 2003, Volume: 126, Issue:1 Topics: Adenosine; Animals; Combined Modality Therapy; Coronary Circulation; Creatine Kinase; Diazoxide; Disease Models, Animal; Flavoproteins; Heart Rate; Ion Channel Gating; Ischemic Preconditioning; Male; Membrane Proteins; Models, Cardiovascular; Myocardial Contraction; Myocardial Ischemia; Myocytes, Cardiac; Necrosis; Nitric Oxide Donors; Oxidation-Reduction; Potassium Channels; Protein Kinase C; Rats; Rats, Sprague-Dawley; Vasodilator Agents; Ventricular Function, Left; Ventricular Pressure	2003
Circulating triglyceride lipolysis facilitates lipoprotein lipase translocation from cardiomyocyte to myocardial endothelial lining. Cardiovascular research, 2003, Sep-01, Volume: 59, Issue:3 Topics: Adenosine; Animals; Biological Transport; Coronary Vessels; Detergents; Diazoxide; Endothelial Cells; Insulin; Lipolysis; Lipoprotein Lipase; Lysophosphatidylcholines; Male; Myocytes, Cardiac; Perfusion; Polyethylene Glycols; Rats; Rats, Wistar; Triglycerides; Vasodilator Agents	2003
Transient mitochondrial permeability transition pore opening mediates preconditioning-induced protection. Circulation, 2004, Apr-13, Volume: 109, Issue:14 Topics: 2,4-Dinitrophenol; Adenosine; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Cardiotonic Agents; Cells, Cultured; Cyclosporine; Diazoxide; Electric Conductivity; Ion Channel Gating; Ion Channels; Ion Transport; Ischemic Preconditioning, Myocardial; Lactones; Macromolecular Substances; Male; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidative Phosphorylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Spiro Compounds; Uncoupling Agents; Vasodilator Agents	2004
Adenosine and a nitric oxide donor enhances cardioprotection by preconditioning with isoflurane through mitochondrial adenosine triphosphate-sensitive K+ channel-dependent and -independent mechanisms. Anesthesiology, 2004, Volume: 100, Issue:3 Topics: Adenosine; Anesthetics, Inhalation; Animals; Cardiovascular Agents; Diazoxide; Dose-Response Relationship, Drug; Flavoproteins; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Isoflurane; Male; Membrane Proteins; Mitochondria, Heart; Myocardial Infarction; Nitric Oxide Donors; Oxidation-Reduction; Potassium Channels; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine	2004
Integrated pharmacological preconditioning and memory of cardioprotection: role of protein kinase C and phosphatidylinositol 3-kinase. American journal of physiology. Heart and circulatory physiology, 2005, Volume: 289, Issue:2 Topics: Adenosine; Animals; Cardiotonic Agents; Caspase 3; Caspase Inhibitors; Cells, Cultured; Diazoxide; DNA Fragmentation; Drug Combinations; Enzyme Activation; Enzyme Inhibitors; Ischemic Preconditioning, Myocardial; L-Lactate Dehydrogenase; Myocytes, Cardiac; Osmolar Concentration; Oxygen; Phosphatidylinositol 3-Kinases; Protein Kinase C; Protein Kinase C-epsilon; Rats; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents	2005
Initiation of remote microvascular preconditioning requires K(ATP) channel activity. American journal of physiology. Heart and circulatory physiology, 2006, Volume: 290, Issue:1 Topics: Adenosine; Animals; Arginine; Arterioles; ATP-Binding Cassette Transporters; Bradykinin; Cricetinae; Cyclic GMP; Decanoic Acids; Diazoxide; Hydroxy Acids; Ischemic Preconditioning; KATP Channels; Male; Mesocricetus; Microcirculation; Nitric Oxide Donors; Nitroprusside; Pinacidil; Potassium Channels, Inwardly Rectifying; Signal Transduction; Vasodilation	2006
Mitochondrial dysfunction as the cause of the failure to precondition the diabetic human myocardium. Cardiovascular research, 2006, Feb-01, Volume: 69, Issue:2 Topics: Adenosine; Adrenergic alpha-Agonists; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diazoxide; Enzyme Activation; Glyburide; Heart Atria; Humans; Hypoglycemic Agents; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Membrane Potentials; Metformin; Mitochondria, Heart; Myocardial Ischemia; p38 Mitogen-Activated Protein Kinases; Phenylephrine; Potassium Channels; Protein Kinase C; Reactive Oxygen Species; Tetradecanoylphorbol Acetate	2006
ATP-sensitive potassium channels mediate the anti-ischemic properties of ischemic and pharmacologic preconditioning in rat random-pattern skin flap. Annals of plastic surgery, 2006, Volume: 57, Issue:1 Topics: Adenosine; Adenosine Triphosphate; Animals; Dermatologic Surgical Procedures; Diazoxide; Glyburide; Hypoglycemic Agents; Ischemia; Ischemic Preconditioning; Male; Morphine; Narcotics; Potassium Channels; Random Allocation; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Skin; Surgical Flaps; Tissue Survival; Vasodilator Agents	2006
Proteomic analysis of pharmacological preconditioning: novel protein targets converge to mitochondrial metabolism pathways. Circulation research, 2006, Sep-29, Volume: 99, Issue:7 Topics: Adenosine; Animals; Diazoxide; Heart Ventricles; Ischemic Preconditioning, Myocardial; Myocardium; Myocytes, Cardiac; Protein Processing, Post-Translational; Proteome; Proteomics; Rabbits	2006
Adenosine and TNF-alpha exert similar inotropic effect on heart cultures, suggesting a cardioprotective mechanism against hypoxia. Life sciences, 2007, Aug-16, Volume: 81, Issue:10 Topics: Adenosine; Animals; Animals, Newborn; Anti-Arrhythmia Agents; Cell Hypoxia; Cell Line; Deoxyglucose; Diazoxide; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Glyburide; Heart; Isoproterenol; Myocardial Contraction; Myocytes, Cardiac; Neuroprotective Agents; Rats; Rubidium Radioisotopes; Sarcoplasmic Reticulum; Tumor Necrosis Factor-alpha	2007
Early opening of sarcolemmal ATP-sensitive potassium channels is not a key step in PKC-mediated cardioprotection. Journal of molecular and cellular cardiology, 2015, Volume: 79 Topics: Action Potentials; Adenosine; Animals; Cardiotonic Agents; Cell Separation; Diazoxide; Enzyme Activation; Heart Failure; Ion Channel Gating; Ischemic Preconditioning, Myocardial; Isoenzymes; KATP Channels; Male; Myocardial Contraction; Myocardial Reperfusion; Myocytes, Cardiac; Phenotype; Pinacidil; Protein Kinase C-epsilon; Protein Kinase Inhibitors; Rats, Wistar; Sarcolemma; Tetradecanoylphorbol Acetate; Time Factors	2015