diazoxide and adenosine diphosphate

diazoxide has been researched along with adenosine diphosphate in 53 studies

Research

Studies (53)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (5.66)	18.7374
1990's	24 (45.28)	18.2507
2000's	23 (43.40)	29.6817
2010's	3 (5.66)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cameron, JS; Ciampolillo, F; Tung, DE	1
Löser, S; Panten, U; Rietze, I; Schwanstecher, M	1
Aspinall, RJ; Dunne, MJ; Petersen, OH	1
Portenhauser, R; Schäfer, G; Trolp, R	2
Dubinsky, WP; Mayorga-Wark, O; Schultz, SG	1
Ayton, BA; Dunne, MJ; Harding, EA; Jaggar, JH	1
Ammälä, C; Bokvist, K; Fredholm, B; Larsson, O; Rorsman, P	1
Detimary, P; Gao, ZY; Gembal, M; Gilon, P; Henquin, JC	1
Amoroso, S; Bernardi, H; De Weille, JR; Epelbaum, J; Fosset, M; Lazdunski, M; Mourre, C; Slama, A	1
Ayton, BJ; Dunne, MJ; Harding, EA; Jaggar, JH	1
Aguilar-Bryan, L; Bryan, J; Clement, JP; Glaser, B; Gonzalez, G; Nestorowicz, A; Nichols, CG; Permutt, MA; Shyng, SL	1
Ashcroft, FM; Gribble, FM; Tucker, SJ	1
Ashcroft, FM; Gribble, FM; Trapp, S; Tucker, SJ; Zhao, C	1
Aguilar-Bryan, L; Bryan, J; Clement, JP; Gonzalez, G; Kunjilwar, K; Panten, U; Schwanstecher, M	1
Berggren, PO; Bränström, R; Höög, A; Larsson, O; Wahl, MA	1
Ferrigni, T; Nichols, CG; Shyng, S	1
Ferrigni, T; Glaser, B; Nestorowicz, A; Nichols, CG; Permutt, MA; Shepard, JB; Shyng, SL	1
Aguilar-Bryan, L; Babenko, AP; Bryan, J; Gonzalez, G	1
Chapal, J; Debrus, S; Hillaire-Buys, D; Loubatières-Mariani, MM; Manteghetti, M; Petit, P	1
Ashcroft, FM; Proks, P; Reimann, F; Tucker, SJ	1
Koster, JC; Nichols, CG; Sha, Q	1
Holmuhamedov, EL; Terzic, A; Wang, L	1
Alekseev, AE; D'hahan, N; Jacquet, H; Moreau, C; Prost, AL; Terzic, A; Vivaudou, M	1
Ammälä, C; Chapman, JC; Cosgrove, KE; Dunne, MJ; Flatt, PR; Giesberts, AN; Hashmi, MN; McClenaghan, NH; Shepherd, RM; White, SJ	1
Ashcroft, FM; Liss, B; Sakura, H; Trapp, S	1
Ovide-Bordeaux, S; Veksler, V; Ventura-Clapier, R	1
Ashcroft, F; Ashfield, R; Huopio, H; Kere, J; Komulainen, J; Laakso, M; Lenko, HL; Otonkoski, T; Rahier, J; Reimann, F; Vauhkonen, I	1
Fujita, A; Inageda, K; Inanobe, A; Katayama, Y; Kurachi, Y; Matsuoka, T; Matsushita, K; Matsuzawa, Y; Tanemoto, M; Yamashita, S	1
Gong, Q; Ichinari, K; Kakei, M; Koriyama, N; Morimitsu, S; Nakazaki, M; Tei, C; Yada, T; Yaekura, K	1
Elmi, A; Idahl, LA; Sehlin, J	1
Holmuhamedov, EL; Jahangir, A; Ozcan, C; Terzic, A	1
Friel, E; Naumann, CM; Ronner, P	1
Fujita, A; Kurachi, Y; Matsuoka, T; Matsushita, K	1
Bienengraeber, M; Dzeja, PP; Ozcan, C; Terzic, A	1
Boudina, S; Dos Santos, P; Garlid, KD; Kowaltowski, AJ; Laclau, MN; Paucek, P; Seetharaman, S; Tariosse, L; Thambo, JB	1
Buntinas, L; Drews, G; Düfer, M; Krippeit-Drews, P; Siemen, D	1
Giblin, JP; Quinn, K; Tinker, A	1
Cartier, EA; Shen, S; Shyng, SL	1
Das, M; Halestrap, AP; Parker, JE	1
Headrick, JP; Peart, J	1
Ala-Rämi, A; Hassinen, IE; Ylitalo, KV	1
Chan, KW; Logothetis, DE; Zhang, H	1
Aspinwall, CA; Berggren, PO; Brandhorst, H; Bränström, R; Corkey, BE; Eckhard, M; Larsson, O; Ostensson, CG; Tibell, A; Välimäki, S	1
Björklund, A; Grill, V; Ma, Z; Yoshikawa, H	1
Dietz, S; Farret, A; Gross, R; Petit, P; Vignaud, M; Vignon, J	1
Beauvoit, B; Bonoron-Adèle, S; Pasdois, P; Santos, PD; Tariosse, L; Vinassa, B	1
Arhem, P; Aspinwall, CA; Berggren, PO; Bränström, R; Corkey, BE; Klement, G; Larsson, O; Leibiger, B; Leibiger, IB; Nilsson, J	1
Becker, S; Ganguly, A; Hanna, C; Lin, YW; MacMullen, C; Pinney, SE; Shyng, SL; Stanley, CA; Thornton, P	1
Maxwell, GM	1
Akrouh, A; Kurata, HT; Lawton, JS; Nichols, CG; Remedi, MS; Zhang, HX	1
Karbalaei, N; Nadimi, E; Noorafshan, A; Safayee, S	1
Barron, D; De Marchi, U; Hermant, A; Ratinaud, Y; Santo-Domingo, J; Thevenet, J; Wiederkehr, A	1

Reviews

1 review(s) available for diazoxide and adenosine diphosphate

Article	Year
[Activation of ATP-sensitive K+ channels by ADP and K+ channel openers: homology model of sulfonylurea receptor carboxyl-termini]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2001, Volume: 118, Issue:3 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Sequence; ATP-Binding Cassette Transporters; Diazoxide; Drug Design; Humans; Molecular Sequence Data; Nicorandil; Nucleotides; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Binding; Protein Conformation; Receptors, Drug; Sequence Homology, Amino Acid; Sulfonylurea Receptors	2001

Article

Year

[Activation of ATP-sensitive K+ channels by ADP and K+ channel openers: homology model of sulfonylurea receptor carboxyl-termini].

Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2001, Volume: 118, Issue:3

Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Sequence; ATP-Binding Cassette Transporters; Diazoxide; Drug Design; Humans; Molecular Sequence Data; Nicorandil; Nucleotides; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Binding; Protein Conformation; Receptors, Drug; Sequence Homology, Amino Acid; Sulfonylurea Receptors

2001

Other Studies

52 other study(ies) available for diazoxide and adenosine diphosphate

Article	Year
Effects of diazoxide and glyburide on ATP-sensitive K+ channels from hypertrophied ventricular myocytes. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:1 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cardiomegaly; Cells, Cultured; Diazoxide; Glyburide; Ion Channel Gating; Male; Potassium; Potassium Channels; Rats; Rats, Inbred SHR; Rats, Inbred Strains	1992
Phosphate and thiophosphate group donating adenine and guanine nucleotides inhibit glibenclamide binding to membranes from pancreatic islets. Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 343, Issue:1 Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Binding, Competitive; Calcium; Diazoxide; Glyburide; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Islets of Langerhans; Kinetics; Magnesium; Membranes; Mice; Microsomes; Organothiophosphates; Phosphates; Phosphorylation; Tritium	1991
The effects of cromakalim on ATP-sensitive potassium channels in insulin-secreting cells. British journal of pharmacology, 1990, Volume: 99, Issue:1 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Benzopyrans; Cell Line; Cromakalim; Diazoxide; Insulin; Insulin Secretion; Islets of Langerhans; Potassium Channels; Potassium Radioisotopes; Pyrroles; Rubidium Radioisotopes; Sodium	1990
Inhibition of mitochondrial metabolism by the diabetogenic thiadiazine diazoxide. II. Interaction with energy conservation and ion transport. Biochemical pharmacology, 1971, Volume: 20, Issue:10 Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Animals; Citric Acid Cycle; Cytochromes; Diazoxide; Drug Antagonism; Electron Transport; Glutamates; Glyburide; Hydroxybutyrates; Ketoglutaric Acids; Male; Mitochondria, Liver; Mitochondria, Muscle; Myocardium; Oxygen Consumption; Polarography; Pyruvates; Rats; Succinates; Uncoupling Agents	1971
Inhibition of mitochondrial metabolism by the diabetogenic thiadiazine diazoxide. I. Action on succinate dehydrogenase and TCA-cycle oxidations. Biochemical pharmacology, 1971, Volume: 20, Issue:6 Topics: Acetoacetates; Adenosine Diphosphate; Animals; Carbon Dioxide; Carbon Isotopes; Carnitine; Citric Acid Cycle; Diazoxide; Flavoproteins; Heart; In Vitro Techniques; Insulin; Insulin Secretion; Kinetics; Malates; Male; Malonates; Mitochondria, Liver; Mitochondria, Muscle; Myocardium; Oxygen Consumption; Palmitic Acids; Pancreas; Pyruvates; Rabbits; Rats; Spectrophotometry; Succinate Dehydrogenase; Uncoupling Agents	1971
Reconstitution of a KATP channel from basolateral membranes of Necturus enterocytes. The American journal of physiology, 1995, Volume: 269, Issue:2 Pt 1 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Diazoxide; Glyburide; Intestine, Small; Membranes; Necturus; Potassium Channels; Tolbutamide	1995
Activation of potassium channels by diazoxide and cromakalim in insulin-secreting cells is dependent upon internal ADP and channel run-down. Biochemical Society transactions, 1993, Volume: 21, Issue:4 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Benzopyrans; Cell Line; Cromakalim; Diazoxide; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Kinetics; Pancreatic Neoplasms; Potassium Channels; Pyrroles; Tumor Cells, Cultured	1993
Stimulation of the KATP channel by ADP and diazoxide requires nucleotide hydrolysis in mouse pancreatic beta-cells. The Journal of physiology, 1993, Volume: 463 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Diazoxide; Electrophysiology; Hydrolysis; In Vitro Techniques; Islets of Langerhans; Kinetics; Magnesium; Mice; Nucleotides; Potassium Channels; Stimulation, Chemical; Time Factors	1993
Mechanisms by which glucose can control insulin release independently from its action on adenosine triphosphate-sensitive K+ channels in mouse B cells. The Journal of clinical investigation, 1993, Volume: 91, Issue:3 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Diazoxide; Diterpenes; Glucose; Inositol Phosphates; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Kinetics; Male; Mice; Mice, Inbred Strains; Phorbol 12,13-Dibutyrate; Potassium; Potassium Channels; Protein Kinase C; Terpenes; Tetradecanoylphorbol Acetate	1993
ATP-modulated K+ channels sensitive to antidiabetic sulfonylureas are present in adenohypophysis and are involved in growth hormone release. Proceedings of the National Academy of Sciences of the United States of America, 1993, Feb-15, Volume: 90, Issue:4 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Animals; Calcium; Cells, Cultured; Diazoxide; Female; Glipizide; Glyburide; Growth Hormone; Hypoglycemic Agents; Kinetics; Membrane Potentials; Oligomycins; Pituitary Gland, Anterior; Potassium Channels; Rats; Receptors, Drug; Sulfonylurea Compounds	1993
Interaction of diazoxide and cromakalim with ATP-regulated K+ channels in rodent and clonal insulin-secreting cells. Journal of molecular endocrinology, 1993, Volume: 10, Issue:1 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Benzopyrans; Cells, Cultured; Cromakalim; Diazoxide; Insulin; Insulin Secretion; Islets of Langerhans; Models, Biological; Potassium Channels; Pyrroles; Rats	1993
Adenosine diphosphate as an intracellular regulator of insulin secretion. Science (New York, N.Y.), 1996, Jun-21, Volume: 272, Issue:5269 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Sequence; Animals; ATP-Binding Cassette Transporters; Cell Line, Transformed; Chlorocebus aethiops; Cricetinae; Diazoxide; Humans; Hyperinsulinism; Hypoglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Molecular Sequence Data; Patch-Clamp Techniques; Point Mutation; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Rubidium; Sulfonylurea Receptors; Transfection	1996
The essential role of the Walker A motifs of SUR1 in K-ATP channel activation by Mg-ADP and diazoxide. The EMBO journal, 1997, Mar-17, Volume: 16, Issue:6 Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antimetabolites; Azides; Cloning, Molecular; Diazoxide; Female; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Magnesium; Mice; Mutagenesis, Site-Directed; Oocytes; Potassium Channels; Protein Conformation; Rats; Sodium Azide; Xenopus	1997
Truncation of Kir6.2 produces ATP-sensitive K+ channels in the absence of the sulphonylurea receptor. Nature, 1997, May-08, Volume: 387, Issue:6629 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Binding Sites; Cell Membrane; Diazoxide; Molecular Sequence Data; Oocytes; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Sequence Deletion; Sulfonylurea Compounds; Sulfonylurea Receptors; Tolbutamide; Xenopus	1997
Association and stoichiometry of K(ATP) channel subunits. Neuron, 1997, Volume: 18, Issue:5 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Animals; COS Cells; Diazoxide; Glyburide; Glycosylation; Histidine; Ion Channel Gating; Molecular Weight; Mutagenesis; Patch-Clamp Techniques; Photochemistry; Potassium Channels; Recombinant Fusion Proteins; Sulfonylurea Compounds	1997
RIN14B: a pancreatic delta-cell line that maintains functional ATP-dependent K+ channels and capability to secrete insulin under conditions where it no longer secretes somatostatin. FEBS letters, 1997, Jul-14, Volume: 411, Issue:2-3 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Diazoxide; Electrophysiology; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Pancreatic Neoplasms; Patch-Clamp Techniques; Potassium Channels; Rats; Somatostatin; Tolbutamide; Tumor Cells, Cultured	1997
Regulation of KATP channel activity by diazoxide and MgADP. Distinct functions of the two nucleotide binding folds of the sulfonylurea receptor. The Journal of general physiology, 1997, Volume: 110, Issue:6 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antihypertensive Agents; ATP-Binding Cassette Transporters; COS Cells; Diazoxide; Hydrolysis; Ion Channel Gating; Kinetics; Magnesium; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Folding; Receptors, Drug; Sulfonylurea Compounds; Sulfonylurea Receptors	1997
Functional analyses of novel mutations in the sulfonylurea receptor 1 associated with persistent hyperinsulinemic hypoglycemia of infancy. Diabetes, 1998, Volume: 47, Issue:7 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alleles; Animals; ATP-Binding Cassette Transporters; COS Cells; Cricetinae; Diazoxide; Humans; Hyperinsulinism; Hypoglycemia; Infant; Infant, Newborn; Insulin; Insulin Secretion; Mice; Mutagenesis, Site-Directed; Pancreas; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Rubidium Radioisotopes; Sulfonylurea Receptors; Transfection	1998
Reconstituted human cardiac KATP channels: functional identity with the native channels from the sarcolemma of human ventricular cells. Circulation research, 1998, Nov-30, Volume: 83, Issue:11 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adolescent; Adult; Animals; ATP-Binding Cassette Transporters; Child; CHO Cells; Cloning, Molecular; COS Cells; Cricetinae; Cromakalim; Diazoxide; DNA, Complementary; Gene Library; Glyburide; Heart Ventricles; Humans; Magnesium; Middle Aged; Myocardium; Patch-Clamp Techniques; Pinacidil; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Receptors, Drug; Sarcolemma; Sulfonylurea Receptors; Tolbutamide; Transfection	1998
Evidence for two different types of P2 receptors stimulating insulin secretion from pancreatic B cell. British journal of pharmacology, 1998, Volume: 125, Issue:6 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Diazoxide; Diuretics; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Potassium Channels; Rats; Rats, Wistar; Receptors, Purinergic P2; Rubidium Radioisotopes; Sodium Chloride Symporter Inhibitors; Thionucleotides	1998
Involvement of the n-terminus of Kir6.2 in coupling to the sulphonylurea receptor. The Journal of physiology, 1999, Jul-15, Volume: 518 ( Pt 2) Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Diazoxide; Diuretics; Electrophysiology; Fungal Proteins; Glycosyltransferases; Hypoglycemic Agents; Ion Channel Gating; Membrane Potentials; Membrane Proteins; Mice; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Repressor Proteins; Saccharomyces cerevisiae Proteins; Sequence Deletion; Sodium Chloride Symporter Inhibitors; Sulfonylurea Compounds; Sulfonylurea Receptors; Tolbutamide; Xenopus laevis	1999
Sulfonylurea and K(+)-channel opener sensitivity of K(ATP) channels. Functional coupling of Kir6.2 and SUR1 subunits. The Journal of general physiology, 1999, Volume: 114, Issue:2 Topics: Adenosine Diphosphate; Animals; ATP-Binding Cassette Transporters; Chlorocebus aethiops; COS Cells; Diazoxide; Diuretics; Electric Stimulation; Electrophysiology; Glycosyltransferases; Hypoglycemic Agents; Ion Channel Gating; KATP Channels; Membrane Potentials; Membrane Proteins; Mutagenesis; Patch-Clamp Techniques; Phosphatidylinositol 4,5-Diphosphate; Polylysine; Potassium Channels; Potassium Channels, Inwardly Rectifying; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Saccharomyces cerevisiae Proteins; Sodium Chloride Symporter Inhibitors; Sulfonylurea Compounds; Tolbutamide	1999
ATP-sensitive K+ channel openers prevent Ca2+ overload in rat cardiac mitochondria. The Journal of physiology, 1999, Sep-01, Volume: 519 Pt 2 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cyclosporine; Diazoxide; In Vitro Techniques; Ionophores; Membrane Potentials; Membrane Proteins; Microscopy, Confocal; Mitochondria, Heart; Myocardium; Oxygen Consumption; Permeability; Pinacidil; Potassium Channels; Rats; Rats, Sprague-Dawley; Valinomycin	1999
Pharmacological plasticity of cardiac ATP-sensitive potassium channels toward diazoxide revealed by ADP. Proceedings of the National Academy of Sciences of the United States of America, 1999, Oct-12, Volume: 96, Issue:21 Topics: Adenosine Diphosphate; Animals; Cricetinae; Cytoplasm; Diazoxide; Guinea Pigs; Mice; Myocardium; Patch-Clamp Techniques; Point Mutation; Potassium; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Recombinant Proteins; Time Factors; Vasodilator Agents; Xenopus	1999
ATP-sensitive potassium channels and efaroxan-induced insulin release in the electrofusion-derived BRIN-BD11 beta-cell line. Diabetes, 1999, Volume: 48, Issue:12 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Benzofurans; Cell Fusion; Cell Line; Diazoxide; Glucose; Imidazoles; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Membrane Potentials; Pancreatic Neoplasms; Phentolamine; Pinacidil; Potassium Channels; Tolbutamide; Tumor Cells, Cultured	1999
Altered functional properties of KATP channel conferred by a novel splice variant of SUR1. The Journal of physiology, 1999, Dec-01, Volume: 521 Pt 2 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alternative Splicing; Amino Acid Sequence; Animals; ATP-Binding Cassette Transporters; Azides; Base Sequence; Brain Chemistry; Cloning, Molecular; Diazoxide; Gene Deletion; Hypoglycemic Agents; Ion Channel Gating; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Mutagenesis; Oocytes; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Rats, Wistar; Receptors, Drug; RNA, Messenger; Sulfonylurea Compounds; Sulfonylurea Receptors; Tolbutamide; Vasodilator Agents; Xenopus	1999
Do modulators of the mitochondrial K(ATP) channel change the function of mitochondria in situ? The Journal of biological chemistry, 2000, Nov-24, Volume: 275, Issue:47 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Creatine Kinase; Diazoxide; Glyburide; Hypoglycemic Agents; KATP Channels; Male; Mitochondria; Oxygen Consumption; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Rats, Wistar	2000
Dominantly inherited hyperinsulinism caused by a mutation in the sulfonylurea receptor type 1. The Journal of clinical investigation, 2000, Volume: 106, Issue:7 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adolescent; Adult; ATP-Binding Cassette Transporters; Binding Sites; Blood Glucose; Child; Child, Preschool; Diazoxide; Female; Finland; Genes, Dominant; Humans; Hyperinsulinism; Male; Mutation, Missense; Pancreas; Pedigree; Polymorphism, Single-Stranded Conformational; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Sulfonylurea Receptors; Tolbutamide	2000
C-terminal tails of sulfonylurea receptors control ADP-induced activation and diazoxide modulation of ATP-sensitive K(+) channels. Circulation research, 2000, Nov-10, Volume: 87, Issue:10 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Cell Line; Diazoxide; Dose-Response Relationship, Drug; Gene Expression; Humans; Intracellular Fluid; Kidney; Mice; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Structure, Tertiary; Receptors, Drug; Recombinant Fusion Proteins; Sulfonylurea Receptors; Transfection; Vasodilator Agents	2000
PIP2 and ATP cooperatively prevent cytosolic Ca2+-induced modification of ATP-sensitive K+ channels in rat pancreatic beta-cells. Diabetes, 2000, Volume: 49, Issue:11 Topics: 2,4-Dinitrophenol; Actins; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cytochalasin D; Cytosol; Diazoxide; Electric Conductivity; Islets of Langerhans; Patch-Clamp Techniques; Phalloidine; Phosphatidylinositol 4,5-Diphosphate; Potassium Channels; Potassium Chloride; Rats; Rats, Wistar; Tolbutamide	2000
Relationships between the Na(+)/K(+) pump and ATP and ADP content in mouse pancreatic islets: effects of meglitinide and glibenclamide. British journal of pharmacology, 2000, Volume: 131, Issue:8 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Benzamides; Diazoxide; Dose-Response Relationship, Drug; Female; Glucose; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Islets of Langerhans; Mice; Mice, Obese; Oxidation-Reduction; Rubidium Radioisotopes; Sodium-Potassium-Exchanging ATPase	2000
Diazoxide protects mitochondria from anoxic injury: implications for myopreservation. The Journal of thoracic and cardiovascular surgery, 2001, Volume: 121, Issue:2 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylate Kinase; Animals; Cell Hypoxia; Diazoxide; Microscopy, Electron; Mitochondria, Heart; Oxidative Phosphorylation; Oxygen Consumption; Potassium Channels; Rats	2001
Effects of glucose and amino acids on free ADP in betaHC9 insulin-secreting cells. Diabetes, 2001, Volume: 50, Issue:2 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acids; Animals; Cell Line; Creatine; Creatine Kinase; Diazoxide; Drug Combinations; Glucagon; Glucagon-Like Peptide 1; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Osmolar Concentration; Peptide Fragments; Phosphocreatine; Potassium Chloride; Protein Precursors; Time Factors	2001
Potassium channel openers protect cardiac mitochondria by attenuating oxidant stress at reoxygenation. American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:2 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Cardiotonic Agents; Cytochrome c Group; Decanoic Acids; Diazoxide; Energy Metabolism; Free Radical Scavengers; Hydroxy Acids; Mitochondria; Myocardial Reperfusion Injury; Myocardium; Nicorandil; Oxidative Phosphorylation; Oxidative Stress; Oxygen Consumption; Potassium; Potassium Channel Blockers; Potassium Channels; Rats; Reactive Oxygen Species; Succinate Dehydrogenase; Vasodilator Agents	2002
Mechanisms by which opening the mitochondrial ATP- sensitive K(+) channel protects the ischemic heart. American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:1 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Respiration; Creatine; Diazoxide; Hemodynamics; In Vitro Techniques; Intracellular Membranes; Male; Mitochondria, Heart; Muscle Fibers, Skeletal; Myocardial Ischemia; Myocardium; Osmolar Concentration; Oxidative Phosphorylation; Perfusion; Permeability; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Sprague-Dawley	2002
Methyl pyruvate stimulates pancreatic beta-cells by a direct effect on KATP channels, and not as a mitochondrial substrate. The Biochemical journal, 2002, Dec-15, Volume: 368, Issue:Pt 3 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cytosol; Diazoxide; Enzyme Inhibitors; Female; Glucose; Humans; Islets of Langerhans; Membrane Potentials; Mice; Mitochondria; NADP; Patch-Clamp Techniques; Potassium Channels; Pyruvates; Pyruvic Acid; Spectrometry, Fluorescence; Substrate Specificity; T-Lymphocytes; Thapsigargin; Vasodilator Agents	2002
The cytoplasmic C-terminus of the sulfonylurea receptor is important for KATP channel function but is not key for complex assembly or trafficking. European journal of biochemistry, 2002, Volume: 269, Issue:21 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Biotinylation; Cell Line; Cell Membrane; Cricetinae; Diazoxide; Fluorescent Antibody Technique; Glyburide; Humans; Kidney; Macromolecular Substances; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Binding; Protein Structure, Tertiary; Protein Transport; Receptors, Drug; Sequence Deletion; Structure-Activity Relationship; Sulfonylurea Receptors; Tolbutamide	2002
Modulation of the trafficking efficiency and functional properties of ATP-sensitive potassium channels through a single amino acid in the sulfonylurea receptor. The Journal of biological chemistry, 2003, Feb-28, Volume: 278, Issue:9 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; ATP-Binding Cassette Transporters; Blotting, Western; COS Cells; Cricetinae; Diazoxide; Dose-Response Relationship, Drug; Glyburide; Immunoblotting; Luminescent Measurements; Magnesium; Mice; Mutation; Patch-Clamp Techniques; Pinacidil; Potassium; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Isoforms; Protein Structure, Tertiary; Protein Transport; Rats; Receptors, Drug; Rubidium; Sulfonylurea Receptors; Time Factors; Transfection; Vasodilator Agents	2003
Matrix volume measurements challenge the existence of diazoxide/glibencamide-sensitive KATP channels in rat mitochondria. The Journal of physiology, 2003, Mar-15, Volume: 547, Issue:Pt 3 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Diazoxide; Diuretics; Glyburide; Hypoglycemic Agents; Light; Magnesium; Male; Mitochondria; Mitochondrial Swelling; Myocardium; Phosphates; Potassium Channel Blockers; Potassium Channels; Potassium Chloride; Rats; Rats, Wistar; Scattering, Radiation; Sodium Chloride Symporter Inhibitors	2003
Adenosine-mediated early preconditioning in mouse: protective signaling and concentration dependent effects. Cardiovascular research, 2003, Jun-01, Volume: 58, Issue:3 Topics: Adenosine; Adenosine Diphosphate; Alkaloids; Animals; Benzophenanthridines; Calcium Channel Blockers; Decanoic Acids; Diazoxide; Enzyme Inhibitors; Hydroxy Acids; Hypoxanthine; Inosine; Ischemic Preconditioning, Myocardial; L-Lactate Dehydrogenase; Male; Mice; Mice, Inbred C57BL; Mitochondria, Heart; Myocardial Contraction; Myocardial Infarction; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Perfusion; Phenanthridines; Phenethylamines; Potassium Channels; Protein Kinase C; Receptors, Purinergic P2; Signal Transduction; Xanthine	2003
Ischaemic preconditioning and a mitochondrial KATP channel opener both produce cardioprotection accompanied by F1F0-ATPase inhibition in early ischaemia. Basic research in cardiology, 2003, Volume: 98, Issue:4 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Cardiotonic Agents; Coronary Circulation; Cytosol; Decanoic Acids; Diazoxide; Flavoproteins; Hydrogen-Ion Concentration; Hydroxy Acids; In Vitro Techniques; Ion Channel Gating; Ischemic Preconditioning, Myocardial; Male; Mitochondria; Myocardial Reperfusion Injury; Oxidation-Reduction; Oxygen Consumption; Potassium Channels; Proton-Translocating ATPases; Rats; Rats, Sprague-Dawley; Vasodilator Agents	2003
N-terminal transmembrane domain of the SUR controls trafficking and gating of Kir6 channel subunits. The EMBO journal, 2003, Aug-01, Volume: 22, Issue:15 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Diazoxide; Glyburide; Ion Channel Gating; Mutagenesis, Site-Directed; Potassium Channels; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Sulfonylurea Receptors; Xenopus	2003
Long-chain CoA esters activate human pancreatic beta-cell KATP channels: potential role in Type 2 diabetes. Diabetologia, 2004, Volume: 47, Issue:2 Topics: Acyl Coenzyme A; Adenosine Diphosphate; Adenosine Triphosphate; Diabetes Mellitus, Type 2; Diazoxide; Dose-Response Relationship, Drug; Glucose; Humans; Islets of Langerhans; Kinetics; Magnesium Chloride; Membrane Potentials; Membrane Proteins; Oleic Acid; Palmitoyl Coenzyme A; Patch-Clamp Techniques; Potassium Channels	2004
Short-term intermittent exposure to diazoxide improves functional performance of beta-cells in a high-glucose environment. American journal of physiology. Endocrinology and metabolism, 2004, Volume: 287, Issue:6 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apoptosis; Cycloheximide; Diazoxide; Dose-Response Relationship, Drug; Drug Administration Schedule; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Oleic Acid; Oxidation-Reduction; Potassium Chloride; Rats; Rats, Sprague-Dawley; SNARE Proteins; Tissue Culture Techniques; Vesicular Transport Proteins	2004
P2Y purinergic potentiation of glucose-induced insulin secretion and pancreatic beta-cell metabolism. Diabetes, 2004, Volume: 53 Suppl 3 Topics: Adenosine Diphosphate; Animals; Diazoxide; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Nitroprusside; Potassium Channels; Rats; Rats, Wistar; Receptors, Purinergic P1; Thionucleotides	2004
MitoK(ATP)-dependent changes in mitochondrial volume and in complex II activity during ischemic and pharmacological preconditioning of Langendorff-perfused rat heart. Journal of bioenergetics and biomembranes, 2006, Volume: 38, Issue:2 Topics: Adenosine Diphosphate; Animals; Antihypertensive Agents; Cell Respiration; Decanoic Acids; Diazoxide; Electron Transport Complex II; Hydroxy Acids; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Male; Mitochondria, Heart; Mitochondrial Size; Myocardial Ischemia; Myocardial Reperfusion; Myofibrils; Potassium Channels; Rats; Rats, Sprague-Dawley; Succinic Acid	2006
Single residue (K332A) substitution in Kir6.2 abolishes the stimulatory effect of long-chain acyl-CoA esters: indications for a long-chain acyl-CoA ester binding motif. Diabetologia, 2007, Volume: 50, Issue:8 Topics: Acyl Coenzyme A; Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Animals; Diazoxide; Female; Humans; Membrane Potentials; Mice; Mice, Obese; Models, Molecular; Molecular Sequence Data; Oocytes; Palmitoyl Coenzyme A; Potassium Channels, Inwardly Rectifying; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Xenopus	2007
Clinical characteristics and biochemical mechanisms of congenital hyperinsulinism associated with dominant KATP channel mutations. The Journal of clinical investigation, 2008, Volume: 118, Issue:8 Topics: Adenosine Diphosphate; Adult; Aged; Aged, 80 and over; Animals; ATP-Binding Cassette Transporters; Chlorocebus aethiops; Congenital Hyperinsulinism; COS Cells; Diazoxide; Female; Genes, Dominant; Glucose Tolerance Test; Heterozygote; Humans; Hypoglycemia; Insulin; Insulin Secretion; KATP Channels; Male; Middle Aged; Mutation; Patch-Clamp Techniques; Pedigree; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Sulfonylurea Receptors	2008
Effects of diazoxide and a dipyridamole derivative on cardiac nucleotide content. Nature: New biology, 1971, Oct-20, Volume: 233, Issue:42 Topics: Adenosine Diphosphate; Adenosine Monophosphate; Animals; Cyclic AMP; Diazoxide; Dipyridamole; Heart; Morpholines; Myocardium; Nucleotides; Rats; Rats, Wistar	1971
HMR 1098 is not an SUR isotype specific inhibitor of heterologous or sarcolemmal K ATP channels. Journal of molecular and cellular cardiology, 2011, Volume: 50, Issue:3 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Benzamides; Blood Glucose; Diazoxide; Insulin; Islets of Langerhans; KATP Channels; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Pinacidil; Potassium Channels, Inwardly Rectifying; Receptors, Drug; Sarcolemma; Substrate Specificity; Sulfonylurea Receptors	2011
Induction of oxidative stress, suppression of glucose-induced insulin release, ATP production, glucokinase activity, and histomorphometric changes in pancreatic islets of hypothyroid rat. European journal of pharmacology, 2016, Nov-15, Volume: 791 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Antioxidants; Calcium Channels, L-Type; Diazoxide; Glucokinase; Glucose; Glyburide; Hexokinase; Hypothyroidism; Insulin; Insulin Secretion; Insulin-Secreting Cells; KATP Channels; Lipid Peroxidation; Oxidative Stress; Phosphorylation; Rats; Rats, Sprague-Dawley; Thyroid Hormones	2016
A novel ATP-synthase-independent mechanism coupling mitochondrial activation to exocytosis in insulin-secreting cells. Journal of cell science, 2017, Jun-01, Volume: 130, Issue:11 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Calcium; Cell Line, Tumor; Diazoxide; Exocytosis; Glucose; Glycolysis; Insulin; Insulin Secretion; Insulin-Secreting Cells; Membrane Potential, Mitochondrial; Mitochondria; Molecular Imaging; Oxygen Consumption; Rats; Single-Cell Analysis; Succinates	2017