diazoxide and acetylcysteine

diazoxide has been researched along with acetylcysteine in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (50.00)29.6817
2010's5 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Forbes, RA; Murphy, E; Steenbergen, C1
Carreira, RS; de Paula, JG; Facundo, HT; Ferranti, R; Kowaltowski, AJ; Laurindo, FR; Santos, CC1
Kucharská, J; Matejíková, J; Pancza, D; Pintérová, M; Ravingerová, T1
Chen, Y; Fan, Z; Huang, L; Lin, W; Tan, W; Wen, T; Yin, C1
Chen, M; Feng, J; Lan, J; Li, J; Liang, W; Song, M; Zhang, W; Zheng, D1

Reviews

1 review(s) available for diazoxide and acetylcysteine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

9 other study(ies) available for diazoxide and acetylcysteine

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Diazoxide-induced cardioprotection requires signaling through a redox-sensitive mechanism.
    Circulation research, 2001, Apr-27, Volume: 88, Issue:8

    Topics: Acetylcysteine; Animals; Cells, Cultured; Diazoxide; Free Radical Scavengers; Glycogen; Heart; Hemodynamics; Hydrogen-Ion Concentration; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Magnetic Resonance Spectroscopy; Male; Myocardial Contraction; Myocardium; Oxidation-Reduction; Phosphates; Phosphocreatine; Phosphorus Isotopes; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Vasodilator Agents; Ventricular Function, Left

2001
Ischemic preconditioning requires increases in reactive oxygen release independent of mitochondrial K+ channel activity.
    Free radical biology & medicine, 2006, Feb-01, Volume: 40, Issue:3

    Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Antioxidants; Catalase; Diazoxide; Hydrogen Peroxide; Ischemic Preconditioning; Male; Mitochondria, Heart; Oxidation-Reduction; Potassium Channels; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

2006
Protection against ischemia-induced ventricular arrhythmias and myocardial dysfunction conferred by preconditioning in the rat heart: involvement of mitochondrial K(ATP) channels and reactive oxygen species.
    Physiological research, 2009, Volume: 58, Issue:1

    Topics: Acetylcysteine; Animals; Anti-Arrhythmia Agents; Antioxidants; Decanoic Acids; Diazoxide; Hydroxy Acids; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Lipid Peroxidation; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Oxidative Stress; Perfusion; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar; Reactive Oxygen Species; Recovery of Function; Thiobarbituric Acid Reactive Substances; Time Factors; Ventricular Function, Left; Ventricular Premature Complexes

2009
Isosteviol Sensitizes sarcKATP Channels towards Pinacidil and Potentiates Mitochondrial Uncoupling of Diazoxide in Guinea Pig Ventricular Myocytes.
    Oxidative medicine and cellular longevity, 2016, Volume: 2016

    Topics: Acetylcysteine; Action Potentials; Animals; Calcium Channels, L-Type; Diazoxide; Diterpenes, Kaurane; Flavoproteins; Fluorescence; Glyburide; Guinea Pigs; Heart Ventricles; Ion Channel Gating; KATP Channels; Mitochondria; Myocytes, Cardiac; Oxidation-Reduction; Pinacidil; Reactive Oxygen Species; Sarcolemma; Time Factors

2016
The Opening of ATP-Sensitive K+ Channels Protects H9c2 Cardiac Cells Against the High Glucose-Induced Injury and Inflammation by Inhibiting the ROS-TLR4-Necroptosis Pathway.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2017, Volume: 41, Issue:3

    Topics: Acetylcysteine; Animals; Apoptosis; Cell Line; Decanoic Acids; Diazoxide; Gene Expression Regulation; Glucose; Glyburide; Hydroxy Acids; Imidazoles; Indoles; Membrane Potential, Mitochondrial; Myocytes, Cardiac; Necrosis; Oxidative Stress; Pinacidil; Potassium Channels; Rats; Reactive Oxygen Species; Receptor-Interacting Protein Serine-Threonine Kinases; Signal Transduction; Sulfonamides; Toll-Like Receptor 4

2017