diazomethane has been researched along with carbobenzoxycarbonyl-l-phenylalanyl-l-alanine-d-diazomethane in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (35.29) | 18.7374 |
| 1990's | 15 (44.12) | 18.2507 |
| 2000's | 5 (14.71) | 29.6817 |
| 2010's | 2 (5.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Auszmann, JM; Kleckner, AP; Rifkin, BR; Rosenberg, LR; Vernillo, AT; Zimmerman, M | 1 |
| Alfieri, SC; Pral, EM; Rabinovitch, M; Ramazeilles, C; Shaw, E | 1 |
| Bailie, JR; Cullen, BM; Halliday, I; Kay, G; McGinty, A; Nelson, J; Walker, B | 1 |
| Alfieri, SC; Rabinovitch, M; Shaw, E; Zilberfarb, V | 1 |
| Hasilik, A; Steckel, F; von Figura, K | 1 |
| Shaw, E | 1 |
| Hoppe, W; Kresse, H; Rauch, U | 1 |
| Cox, SW; Eley, BM | 1 |
| Mort, JS; Recklies, AD | 1 |
| Grinde, B | 1 |
| Cockle, SM; Dean, RT | 2 |
| Bohley, P; Brouwer, A; Kirschke, H; Riemann, S; Shaw, E; Wiederanders, B | 1 |
| Kirschke, H; Shaw, E | 1 |
| Dean, RT; Shaw, E | 1 |
| Ambroso, JL; Harris, C | 1 |
| Coombs, GH; North, MJ; Scott, DA | 1 |
| Claeys, E; Demeyer, D; Uytterhaegen, L | 1 |
| Alfieri, SC; Balanco, JM; Bijovsky, AT; Pral, EM | 1 |
| Bogitsh, BJ; Carter, CE; Ribeiro-Rodrigues, R | 1 |
| Bednarski, E; Lynch, G | 1 |
| Bednarski, E; Lynch, G; Ribak, CE | 1 |
| Bednarski, E; Gall, CM; Lauterborn, JC; Lynch, G | 1 |
| Bi, X; Gall, CM; Lynch, G; Nguyen, K; Pinkstaff, J | 1 |
| Caffrey, CR; Ruppel, A; Scory, S; Steverding, D; Stierhof, YD | 1 |
| Bednarski, E; Gall, CM; Lynch, G; Ribak, CE; Yong, AP | 1 |
| Bi, X; Lynch, G; Zhou, J | 1 |
| Bi, X; Ellman, JA; Haque, TS; Kuntz, ID; Lee, CE; Lin, B; Lynch, G; Skillman, AG; Zhou, J | 1 |
| Bahr, BA; Bendiske, J | 1 |
| Aguilar, A; Bi, X; Díaz-Cintra, S; Lynch, G; Ribak, CE; Yong, A | 1 |
| Apsel, B; Baca, AM; Chiang, PK; Guy, KR; Hansell, EJ; Mackey, ZB; Mallari, JP; McKerrow, JH; Shelat, A; Williams, J; Wolff, B | 1 |
| Dalton, JP; Horák, P; Kasný, M; Mikes, L; Mountford, AP | 1 |
| Bayrak, BB; Bolkent, S; Gezginci-Oktayoglu, S; Oztay, F; Yanardag, R | 1 |
| Bahr, BA; Bowers, MT; Gessel, MM; Viswanathan, K; Wisniewski, ML; Wright, DL; Zheng, X | 1 |
34 other study(ies) available for diazomethane and carbobenzoxycarbonyl-l-phenylalanyl-l-alanine-d-diazomethane
| Article | Year |
|---|---|
Cathepsin B and L activities in isolated osteoclasts.
Topics: Animals; Bone Resorption; Cathepsin B; Cathepsin L; Cathepsins; Cells, Cultured; Chickens; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Diazomethane; Endopeptidases; Kinetics; Osteoclasts; Substrate Specificity | 1991 |
Leishmania amazonensis: specific labeling of amastigote cysteine proteinases by radioiodinated N-benzyloxycarbonyl-tyrosyl-alanyl diazomethane.
Topics: Animals; Autoradiography; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Diazomethane; Dipeptides; Iodine Radioisotopes; Kinetics; Leishmania mexicana; Molecular Weight | 1991 |
Synthesis and activity of a novel, irreversible inhibitor of cathepsin B.
Topics: Animals; Binding Sites; Biotin; Cathepsin B; Cattle; Cysteine Proteinase Inhibitors; Diazomethane; In Vitro Techniques | 1990 |
Leishmania amazonensis: involvement of cysteine proteinases in the killing of isolated amastigotes by L-leucine methyl ester.
Topics: Animals; Cysteine Endopeptidases; Diazomethane; Electrophoresis, Polyacrylamide Gel; Leishmania mexicana; Leucine; Macrophages; Mice; Protease Inhibitors; Substrate Specificity | 1989 |
Multiple sulfatase deficiency: degradation of arylsulfatase A and B after endocytosis in fibroblasts.
Topics: Cells, Cultured; Cerebroside-Sulfatase; Chondro-4-Sulfatase; Diazomethane; Endocytosis; Fibroblasts; Humans; Sulfatases | 1985 |
Peptidyl sulfonium salts. A new class of protease inhibitors.
Topics: Affinity Labels; Cathepsin B; Diazomethane; Hydrogen-Ion Concentration; Onium Compounds; Papain; Peptides; Protease Inhibitors; Spectrophotometry, Ultraviolet; Sulfonium Compounds | 1988 |
Degradation of endocytosed dermatan sulfate proteoglycan in human fibroblasts.
Topics: Ammonium Chloride; Biological Transport; Cells, Cultured; Chondroitin; Chondroitin Sulfate Proteoglycans; Cycloheximide; Dermatan Sulfate; Diazomethane; Endocytosis; Fibroblasts; Half-Life; Humans; Kinetics; Leucine; Leupeptins; Lysosomes; Molecular Weight; Protease Inhibitors; Proteoglycans; Sulfates | 1988 |
Preliminary studies on cysteine and serine proteinase activities in inflamed human gingiva using different 7-amino-4-trifluoromethyl coumarin substrates and protease inhibitors.
Topics: Adult; Coumarins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Diazomethane; Enzyme Activation; Female; Gingivitis; Humans; Male; Middle Aged; Protease Inhibitors; Serine Endopeptidases; Serine Proteinase Inhibitors; Substrate Specificity | 1987 |
Rat mammary gland in culture secretes a stable high molecular weight form of cathepsin L.
Topics: Animals; Cathepsin B; Cathepsin L; Cathepsins; Culture Techniques; Cysteine Endopeptidases; Diazomethane; Endopeptidases; Female; Hydrogen-Ion Concentration; Lactation; Leupeptins; Mammary Glands, Animal; Molecular Weight; Pregnancy; Rats; Rats, Inbred Strains; Substrate Specificity | 1985 |
The thiol proteinase inhibitors, Z-Phe-PheCHN2 and Z-Phe-AlaCHN2, inhibit lysosomal protein degradation in isolated rat hepatocytes.
Topics: alpha-Fetoproteins; Animals; Asialoglycoproteins; Diazomethane; Dimethyl Sulfoxide; Fetuins; In Vitro Techniques; Liver; Lysosomes; Male; Protease Inhibitors; Protein Biosynthesis; Proteins; Rats; Rats, Inbred Strains | 1983 |
Degradation of intracellular proteins in macrophages and fibroblasts.
Topics: Animals; Cell Division; Cell Line; Cells, Cultured; Cysteine Endopeptidases; Diazomethane; Endopeptidases; Fibroblasts; Half-Life; Lysosomes; Macrophages; Mice; Protease Inhibitors; Proteins | 1981 |
Inhibition of cysteine proteinase activity by Z-Phe-Phe-diazomethane and of aspartic proteinase activity by pepstatin in different organs from some animals and isolated cells from rat liver.
Topics: Animals; Aspartic Acid Endopeptidases; Carps; Cathepsin B; Cathepsin L; Cathepsins; Columbidae; Cysteine Endopeptidases; Diazomethane; Endopeptidases; Kidney; Liver; Myocardium; Oligopeptides; Pepstatins; Protease Inhibitors; Ranidae; Rats; Spleen; Tissue Distribution | 1982 |
The regulation of proteolysis in normal fibroblasts as they approach confluence. Evidence for the participation of the lysosomal system.
Topics: Ammonium Chloride; Animals; Cells, Cultured; Diazomethane; Fibroblasts; Humans; Leupeptins; Lysosomes; Mice; Pepstatins; Proteins | 1982 |
Rapid interaction of cathepsin L by Z-Phe-PheCHN12 and Z-Phe-AlaCHN2.
Topics: Animals; Cathepsin L; Cathepsins; Cattle; Cysteine Endopeptidases; Diazomethane; Endopeptidases; Humans; Kinetics; Liver; Organ Specificity; Protease Inhibitors; Rats; Species Specificity; Spleen | 1981 |
The inhibition of macrophage protein turnover by a selective inhibitor of thiol proteinases.
Topics: Animals; Cells, Cultured; Diazomethane; Dose-Response Relationship, Drug; Kinetics; Macrophages; Mice; Pepstatins; Protease Inhibitors; Proteins | 1980 |
In vitro embryotoxicity of the cysteine proteinase inhibitors benzyloxycarbonyl-phenylalanine-alanine-diazomethane (Z-Phe-Ala-CHN2) and benzyloxycarbonyl-phenylalanine-phenylalanine-diazomethane (Z-Phe-Phe-CHN2).
Topics: Animals; Cysteine Proteinase Inhibitors; Diazomethane; Embryo, Mammalian; Female; Hydrolysis; Pregnancy; Rats; Rats, Sprague-Dawley; Teratogens; Yolk Sac | 1994 |
Trichomonas vaginalis: amoeboid and flagellated forms synthesize similar proteinases.
Topics: Animals; Caseins; Culture Media; Cysteine Proteinase Inhibitors; Diazomethane; Endopeptidases; Leucine; Leupeptins; Lipoproteins; Trichomonas vaginalis | 1995 |
Effects of exogenous protease effectors on beef tenderness development and myofibrillar degradation and solubility.
Topics: Animals; Calcimycin; Calcium; Calpain; Cathepsins; Cattle; Cysteine Proteinase Inhibitors; Diazomethane; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Glycoproteins; Leucine; Leupeptins; Male; Meat; Muscle Proteins; Muscles; Octoxynol; Pepstatins; Phenylmethylsulfonyl Fluoride; Postmortem Changes; Solubility | 1994 |
Leishmania mexicana: proteinase activities and megasomes in axenically cultivated amastigote-like forms.
Topics: Animals; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Diazomethane; Dipeptides; Endopeptidases; Leishmania mexicana; Mice; Mice, Inbred BALB C; Microscopy, Electron; Organelles; Temperature | 1993 |
An ultrastructure study of the in vitro effects of L-leucine methyl ester and ammonium chloride on Trypanosoma cruzi epimastigotes.
Topics: Ammonium Chloride; Animals; Cysteine Proteinase Inhibitors; Diazomethane; Leucine; Lysosomes; Microscopy, Electron; Organelles; Trypanosoma cruzi | 1996 |
Cytosolic proteolysis of tau by cathepsin D in hippocampus following suppression of cathepsins B and L.
Topics: Animals; Cathepsin B; Cathepsin D; Cathepsin L; Cathepsins; Cell Fractionation; Cerebral Cortex; Cysteine Endopeptidases; Cytosol; Diazomethane; Endopeptidases; Hippocampus; Lysosomes; Microtubules; Okadaic Acid; Organ Culture Techniques; Protease Inhibitors; Protein Binding; Rats; Rats, Sprague-Dawley; tau Proteins; Tubulin | 1996 |
Suppression of cathepsins B and L causes a proliferation of lysosomes and the formation of meganeurites in hippocampus.
Topics: Animals; Cathepsin B; Cathepsin L; Cathepsins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Diazomethane; Endopeptidases; Enzyme Precursors; Hippocampus; Hydrolases; Lysosomes; Microscopy, Electron; Nerve Degeneration; Neurites; Organ Culture Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley | 1997 |
Lysosomal dysfunction reduces brain-derived neurotrophic factor expression.
Topics: Aging; Animals; Brain-Derived Neurotrophic Factor; Cathepsin B; Cathepsin L; Cathepsins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Densitometry; Dentate Gyrus; Diazomethane; Endopeptidases; Gene Expression Regulation; Hippocampus; Kainic Acid; Lysosomes; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1998 |
Experimentally induced lysosomal dysfunction disrupts processing of hypothalamic releasing factors.
Topics: Animals; Cathepsin B; Cathepsin L; Cathepsins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Diazomethane; Endopeptidases; Growth Hormone-Releasing Hormone; Hypothalamus; Immunohistochemistry; In Vitro Techniques; Lysosomes; Rats; Rats, Sprague-Dawley; RNA, Messenger; Somatostatin | 1998 |
Trypanosoma brucei: killing of bloodstream forms in vitro and in vivo by the cysteine proteinase inhibitor Z-phe-ala-CHN2.
Topics: Animals; Cysteine Proteinase Inhibitors; Diazomethane; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred BALB C; Multiple Myeloma; Trypanosoma brucei brucei; Trypanosomiasis, African; Tumor Cells, Cultured | 1999 |
Lysosomal dysfunction results in lamina-specific meganeurite formation but not apoptosis in frontal cortex.
Topics: Animals; Apoptosis; Culture Techniques; Diazomethane; DNA Fragmentation; Frontal Lobe; In Situ Nick-End Labeling; Lysosomes; Neurites; Rats; Rats, Sprague-Dawley | 1999 |
Lysosomal protease inhibitors induce meganeurites and tangle-like structures in entorhinohippocampal regions vulnerable to Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Animals; Cathepsin B; Cathepsin L; Cathepsins; Chloroquine; Cysteine Endopeptidases; Diazomethane; Endopeptidases; Entorhinal Cortex; Hippocampus; Humans; Lysosomes; Neurites; Neurofibrillary Tangles; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Serine Proteinase Inhibitors | 1999 |
Novel cathepsin D inhibitors block the formation of hyperphosphorylated tau fragments in hippocampus.
Topics: Alzheimer Disease; Animals; Cathepsin D; Diazomethane; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Hippocampus; Lysosomes; Organ Culture Techniques; Peptide Fragments; Phosphoproteins; Phosphorylation; Rats; Rats, Sprague-Dawley; tau Proteins | 2000 |
Lysosomal activation is a compensatory response against protein accumulation and associated synaptopathogenesis--an approach for slowing Alzheimer disease?
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cathepsins; Chloroquine; Culture Techniques; Cysteine Proteinase Inhibitors; Diazomethane; Disease Models, Animal; Enzyme Activation; Hippocampus; Hydrolases; Lysosomes; Rats; Rats, Sprague-Dawley; Synapses; tau Proteins | 2003 |
Ultrastructural analysis of hippocampal pyramidal neurons from apolipoprotein E-deficient mice treated with a cathepsin inhibitor.
Topics: Animals; Apolipoproteins E; Cathepsins; Diazomethane; Mice; Mice, Inbred C57BL; Mice, Knockout; Protease Inhibitors; Pyramidal Cells | 2004 |
Discovery of trypanocidal compounds by whole cell HTS of Trypanosoma brucei.
Topics: Animals; Diazomethane; Drug Evaluation, Preclinical; Humans; Luminescent Measurements; Molecular Structure; Parasitic Sensitivity Tests; Trypanocidal Agents; Trypanosoma brucei brucei | 2006 |
Comparison of cysteine peptidase activities in Trichobilharzia regenti and Schistosoma mansoni cercariae.
Topics: Animals; Binding Sites; Chromatography, Gel; Collagen; Cysteine Endopeptidases; Diazomethane; Gelatin; Hydrogen-Ion Concentration; Keratins; Leucine; Protease Inhibitors; Schistosoma mansoni; Schistosomatidae | 2007 |
Cathepsin B inhibition improves lung injury associated to D-galactosamine/tumor necrosis factor-alpha-induced liver injury in mice.
Topics: Animals; Apoptosis; Cathepsin B; Cell Proliferation; Chemical and Drug Induced Liver Injury; Cysteine Proteinase Inhibitors; Diazomethane; Galactosamine; Lung Injury; Male; Mice; Mice, Inbred BALB C; Tumor Necrosis Factor-alpha | 2010 |
Z-Phe-Ala-diazomethylketone (PADK) disrupts and remodels early oligomer states of the Alzheimer disease Aβ42 protein.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloidosis; Animals; Diazomethane; Dimerization; Disease Models, Animal; Drug Design; Humans; Mass Spectrometry; Mice; Microscopy, Electron; Peptide Fragments; Protein Folding; Protein Structure, Secondary; Solubility | 2012 |