diazepam and triazoles

diazepam has been researched along with triazoles in 56 studies

Research

Studies (56)

Timeframe	Studies, this research(%)	All Research%
pre-1990	15 (26.79)	18.7374
1990's	14 (25.00)	18.2507
2000's	18 (32.14)	29.6817
2010's	8 (14.29)	24.3611
2020's	1 (1.79)	2.80

Authors

Authors	Studies
Collins, RJ; Gall, M; Kamdar, BV	1
Haas, HL; Wolf, P	1
Biagi, G; Livi, O; Lucacchini, A; Martini, C; Scartoni, V	1
Dudley, MW; Kane, JM; Kehne, JH; Miller, JA; Sorensen, SM	1
Ashton, D; Clincke, GH; Fransen, J; Heeres, J; Janssen, PA	1
Barbaz, BS; Bernard, PS; Braunwalder, AF; Cash, WD; Francis, JE; Friedmann, RC; Hyun, JL; Loo, PS; Lovell, RA; Mazzenga, GC	1
Mikashima, H; Muramoto, Y; Setoguchi, M; Tahara, T; Takehara, S; Terasawa, M	1
Raffa, RB; Setler, PE; Vaught, JL	1
Biagi, G; Livi, O; Lucacchini, A; Marrucci, W; Martini, C	1
Barone, D; Occelli, E; Tarzia, G	1
Udabe, RU	1
Chiba, S; Nagawa, Y	1
Fukuda, N; Nagawa, Y; Saji, Y	1
Moriya, R; Nagawa, Y; Nakajima, R; Saji, Y; Take, Y; Yui, T	1
Maletzky, BM	1
Albright, JD; Beer, B; Collins, JB; Greenblatt, EN; Lippa, AS; Moran, DB; Wright, WB	1
Fujimoto, M; Hashimoto, S; Hatakeyama, H; Hirose, K; Okabayashi, T; Takahashi, S	1
Horiuchi, M; Inoue, Y; Yamamoto, K; Yoshimura, K	1
Benjamin, L; Fryer, RI; Trybulski, EJ; Vitone, S; Walser, A	1
Aden, GC; Thein, SG	1
Nicholson, AN; Pascoe, PA; Stone, BM	1
Biggio, G; Ghiani, CA; Maciocco, E; Sanna, E; Serra, M; Tuligi, G	1
Kapur, J; Macdonald, RL	1
Korpi, ER; Matecka, D; Sarviharju, M; Toropainen, M; Wong, G	1
Biggio, G; Casula, A; Maciocco, E; Murgia, A; Sanna, E; Tuligi, G; Usala, M	1
Greenfield, LJ; Macdonald, RL; Neelands, TR; Turner, RS; Zhang, J	1
Cseppentö, A; Kovács, P; Nagy, E; Szabó, JZ; Szentmiklósi, AJ; Ujfalusi, A	1
Kapur, J; Macdonald, RL; Tietz, EI	1
Macdonald, RL; Neelands, TR; Zhang, J	1
Carlisle, HJ; Davies, PA; Hales, TG; Hoffmann, EB; Tyndale, RF	1
Sapp, DW; Yeh, HH	1
Atack, JR; Bristow, L; Brown, N; Carling, RW; Castro, JL; Cook, G; Dawson, GR; Farrar, S; Ferris, P; Garrett, L; Howell, O; Macaulay, A; Marshall, G; McKernan, RM; Moore, KW; Myers, J; Ragan, CI; Reynolds, DS; Rosahl, TW; Street, LJ; Sur, C; Wafford, KA; Whiting, PJ	1
Saxena, NC	1
Dawson, GR; McKernan, RM; Reynolds, DS	1
Dillon, GH; Huang, RQ	1
Akbarzadeh, T; Khoshnoud, MJ; Shafaghi, B; Shafiee, A; Tabatabai, SA	1
Kiss, A; Mikkelsen, JD; Mirza, N; Søderman, A	1
Kapur, J; Mtchedlishvili, Z	1
Camenisch, GP; Fresneau, M; Gross, G; Kretz, O; Weiss, HM	1
Groenink, L; Olivier, B; Oosting, R; Toth, M; Van Bogaert, M; van Oorschot, R	1
Bradshaw, CM; Hou, RH; Langley, RW; Samuels, ER; Szabadi, E	1
Bertilsson, L; Laine, K; Neuvonen, PJ; Olkkola, KT; Saari, TI	1
Ahmadi, S; Brockhaus, J; Brune, K; Fritschy, JM; Hess, A; Hösl, K; Knabl, J; Möhler, H; Reinold, H; Rudolph, U; Sergejeva, M; Witschi, R; Zeilhofer, HU; Zeilhofer, UB	1
Bostwick, R; Chen, T; Huston, J; Knappenberger, K; Liu, J; Norris, T; Wood, M	1
Bundzikova, J; Hansen, HH; Kiss, A; Larsen, MH; Mikkelsen, JD	1
Evenden, J; Jonak, G; Ross, L; Zhou, J	1
Clifton, PG; Dixon, CI; Morris, HV; Nilsson, S; Stephens, DN	1
Atack, JR; Cook, JM; Dawson, GR; Licata, SC; Platt, DM; Rowlett, JK; Rüedi-Bettschen, D; Van Linn, ML	1
Atack, JR	2
Cook, JM; Groenink, L; Hansen, HH; Mirza, NR; Nielsen, EØ; Olivier, B; van Oorschot, R; Vinkers, CH	1
Brown, DT; Erichsen, HK; Hansen, RR; Mirza, NR; Munro, G	1
Binns, J; Bowlby, MR; Brunner, J; Cannon, CE; Coleman, PJ; Eddins, DM; Fox, SV; Garson, SL; Gotter, AL; Hodgson, R; Kuduk, SD; Mcdonald, TP; Renger, JJ; Savitz, AT; Stevens, J; Tannenbaum, PL; Tye, SJ; Uslaner, JM; Wang, X; Winrow, CJ; Yao, L	1
Ator, NA; Biawat, P; Clayton, T; Cook, JM; Rallapalli, SK; Soto, PL; Weed, MR	1
Coleman, PJ; Fox, SV; Gotter, AL; Hargreaves, R; Kuduk, SD; Renger, JJ; Savitz, AT; Stevens, J; Tannenbaum, PL; Tye, SJ; Uslaner, JM; Winrow, CJ	1
García-Peñas, JJ; Gil Nagel-Rein, A; Sánchez-Carpintero, R; Villanueva-Haba, V	1

Reviews

4 review(s) available for diazepam and triazoles

Article	Year
Clinical experience with a new psychotropic drug, trazodone: a review of literature. Current therapeutic research, clinical and experimental, 1973, Volume: 15, Issue:10 Topics: Amitriptyline; Antidepressive Agents; Anxiety; Chlordiazepoxide; Clinical Trials as Topic; Depression; Diazepam; Drug Tolerance; Humans; Imipramine; Piperazines; Pyridines; Schizophrenia; Tranquilizing Agents; Triazoles	1973
GABAA receptor subtype-selective modulators. II. α5-selective inverse agonists for cognition enhancement. Current topics in medicinal chemistry, 2011, Volume: 11, Issue:9 Topics: Animals; Benzodiazepines; Cognition; Diazepam; Female; Fluorobenzenes; GABA-A Receptor Agonists; Hippocampus; Humans; Isoxazoles; Male; Maze Learning; Memory; Mice; Nootropic Agents; Protein Isoforms; Pyridazines; Pyridines; Rats; Receptors, GABA-A; Structure-Activity Relationship; Substrate Specificity; Triazines; Triazoles	2011
GABAA receptor subtype-selective modulators. I. α2/α3-selective agonists as non-sedating anxiolytics. Current topics in medicinal chemistry, 2011, Volume: 11, Issue:9 Topics: Animals; Anti-Anxiety Agents; Benzimidazoles; Benzodiazepines; Diazepam; Dogs; Fluorobenzenes; GABA-A Receptor Agonists; Humans; Hypnotics and Sedatives; Male; Mice; Mice, Transgenic; Protein Isoforms; Pyridazines; Pyridines; Rats; Receptors, GABA-A; Structure-Activity Relationship; Substrate Specificity; Triazoles	2011
Cannabidiol for the treatment of Lennox-Gastaut syndrome and Dravet syndrome: experts' recommendations for its use in clinical practice in Spain. Revista de neurologia, 2021, 09-10, Volume: 73, Issue:S01 Topics: Anticonvulsants; Cannabidiol; Clobazam; Clonazepam; Diazepam; Dioxolanes; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Epilepsies, Myoclonic; Humans; Lennox Gastaut Syndrome; Phenobarbital; Practice Guidelines as Topic; Pyrrolidinones; Spain; Triazoles; Valproic Acid	2021

Trials

6 trial(s) available for diazepam and triazoles

Article	Year
Clinical experience with a new psychotropic drug, trazodone: a review of literature. Current therapeutic research, clinical and experimental, 1973, Volume: 15, Issue:10 Topics: Amitriptyline; Antidepressive Agents; Anxiety; Chlordiazepoxide; Clinical Trials as Topic; Depression; Diazepam; Drug Tolerance; Humans; Imipramine; Piperazines; Pyridines; Schizophrenia; Tranquilizing Agents; Triazoles	1973
Anxiolytic efficacy of alprazolam compared to diazepam and placebo. The Journal of international medical research, 1980, Volume: 8, Issue:2 Topics: Adolescent; Adult; Aged; Alprazolam; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Clinical Trials as Topic; Diazepam; Double-Blind Method; Humans; Middle Aged; Placebos; Psychiatric Status Rating Scales; Triazoles	1980
Alprazolam compared to diazepam and placebo in the treatment of anxiety. The Journal of clinical psychiatry, 1980, Volume: 41, Issue:7 Topics: Adolescent; Adult; Aged; Alprazolam; Anxiety; Benzodiazepines; Clinical Trials as Topic; Diazepam; Double-Blind Method; Female; Humans; Male; Middle Aged; Placebos; Triazoles	1980
Studies on sleep and performance with a triazolo-1, 4-thienodiazepine (brotizolam). British journal of clinical pharmacology, 1980, Volume: 10, Issue:1 Topics: Adolescent; Adult; Azepines; Diazepam; Half-Life; Humans; Hypnotics and Sedatives; Male; Motor Skills; Sleep; Sleep Stages; Sleep, REM; Task Performance and Analysis; Triazoles	1980
Arousal and the pupil: why diazepam-induced sedation is not accompanied by miosis. Psychopharmacology, 2007, Volume: 195, Issue:1 Topics: Administration, Oral; Adult; Anti-Anxiety Agents; Arousal; Cardiovascular Physiological Phenomena; Cold Temperature; Conscious Sedation; Cross-Over Studies; Darkness; Diazepam; Double-Blind Method; Humans; Male; Miosis; Parasympatholytics; Photic Stimulation; Piperazines; Pupil; Reflex, Pupillary; Salivation; Sympatholytics; Triazoles; Tropicamide	2007
Voriconazole and fluconazole increase the exposure to oral diazepam. European journal of clinical pharmacology, 2007, Volume: 63, Issue:10 Topics: Administration, Oral; Adult; Antifungal Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cognition; Cross-Over Studies; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diazepam; Drug Interactions; Enzyme Inhibitors; Female; Fluconazole; Genotype; Half-Life; Humans; Hypnotics and Sedatives; Male; Mixed Function Oxygenases; Nordazepam; Pyrimidines; Triazoles; Voriconazole; Wakefulness	2007

Other Studies

47 other study(ies) available for diazepam and triazoles

Article	Year
Pharmacology of some metabolites of triazolam, alprazolam, and diazepam prepared by a simple, one-step oxidation of benzodiazepines. Journal of medicinal chemistry, 1978, Volume: 21, Issue:12 Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Diazepam; Hydroxylation; Male; Methods; Mice; Oxidation-Reduction; Triazolam; Triazoles	1978
Effects of diazepines and barbiturates on hippocampal recurrent inhibition. Naunyn-Schmiedeberg's archives of pharmacology, 1977, Volume: 299, Issue:3 Topics: Animals; Benzodiazepines; Cerebral Cortex; Diazepam; Electric Stimulation; Evoked Potentials; Hippocampus; Neural Inhibition; Pentobarbital; Phenobarbital; Rats; Substantia Nigra; Thiamylal; Time Factors; Triazoles	1977
Specific inhibition of binding to benzodiazepine receptors by 1,2,3-triazole derivatives. Journal of pharmaceutical sciences, 1992, Volume: 81, Issue:6 Topics: Animals; Benzodiazepinones; Binding, Competitive; Cattle; Cerebral Cortex; Diazepam; In Vitro Techniques; Protein Binding; Receptors, GABA-A; Triazoles	1992
MDL 26,479: a potential cognition enhancer with benzodiazepine inverse agonist-like properties. British journal of pharmacology, 1992, Volume: 107, Issue:1 Topics: Animals; Behavior, Animal; Benzodiazepines; Binding Sites; Carbolines; Cognition; Convulsants; Diazepam; Flumazenil; Hemicholinium 3; Hippocampus; In Vitro Techniques; Male; Mice; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Triazoles	1992
In vivo studies on the mechanism of action of the broad spectrum anticonvulsant loreclezole. Epilepsy research, 1992, Volume: 11, Issue:1 Topics: Animals; Anticonvulsants; Diazepam; Electric Stimulation; Kindling, Neurologic; Male; Pentobarbital; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures; Triazoles	1992
Synthesis and benzodiazepine binding activity of a series of novel [1,2,4]triazolo[1,5-c]quinazolin-5(6H)-ones. Journal of medicinal chemistry, 1991, Volume: 34, Issue:1 Topics: Animals; Binding, Competitive; Brain; Diazepam; Flunitrazepam; Indicators and Reagents; Molecular Structure; Quinazolines; Rats; Receptors, GABA-A; Structure-Activity Relationship; Triazoles	1991
Pharmacological actions of Y-24180, a new specific antagonist of platelet activating factor (PAF): II. Interactions with PAF and benzodiazepine receptors. Prostaglandins, 1990, Volume: 40, Issue:6 Topics: Animals; Azepines; Binding, Competitive; Blood Platelets; Brain; Diazepam; Humans; In Vitro Techniques; Male; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rabbits; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, GABA-A; Triazoles	1990
The novel anticonvulsant loreclezole (R 72063) does not produce diazepam-like anterograde amnesia in a passive avoidance test in rats. Naunyn-Schmiedeberg's archives of pharmacology, 1990, Volume: 342, Issue:5 Topics: Amnesia; Animals; Anticonvulsants; Avoidance Learning; Diazepam; Male; Rats; Rats, Inbred Strains; Scopolamine; Triazoles	1990
Specific inhibition of benzodiazepine receptor binding by some 1,2,3-triazole derivatives. Journal of pharmaceutical sciences, 1988, Volume: 77, Issue:11 Topics: Animals; Binding, Competitive; Brain; Cattle; Chemical Phenomena; Chemistry; Diazepam; In Vitro Techniques; Kinetics; Receptors, GABA-A; Spectrophotometry, Infrared; Structure-Activity Relationship; Triazoles	1988
Benzodiazepine receptor ligands. Synthesis and pharmacological evaluation of 6-aryl-3,8-disubstituted-1,2,4-triazolo[3,4-a]phthalazines. Il Farmaco; edizione scientifica, 1988, Volume: 43, Issue:11 Topics: Animals; Avoidance Learning; Brain; Diazepam; Male; Mice; Phthalazines; Pyridazines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Structure-Activity Relationship; Synaptosomes; Triazoles	1988
Effects of new s-triazolobenzododiazepine (D-40TA) and other central muscle relaxants on spinal and supraspinal reflexes in cats. Japanese journal of pharmacology, 1973, Volume: 23, Issue:1 Topics: Animals; Benzazepines; Blood Pressure; Cats; Chlormezanone; Chlorzoxazone; Decerebrate State; Diazepam; Electromyography; Evoked Potentials; Female; Male; Mandible; Mephenesin; Methocarbamol; Motor Activity; Muscle Relaxants, Central; Muscle Tonus; Nitrazepam; Patella; Reflex; Spine; Triazoles	1973
Neuropharmacological studies of effect of new central depressant, 8-chloro-6-phenyl-4H-s-triazolo (4,3-a) (1,4) benzodiazepine (D-40TA) on EEG and central sympathetic activating mechanism in cats. Japanese journal of pharmacology, 1974, Volume: 24, Issue:1 Topics: Animals; Arousal; Benzazepines; Brain; Cats; Diazepam; Electroencephalography; Female; Hypothalamus; Male; Nitrazepam; Reticular Formation; Sciatic Nerve; Sympathetic Nervous System; Thalamus; Triazoles	1974
Pharmacological studies on new potent central depressants, 8-chloro-6-phenyl-4H-s-triazolo [4,3a][1,4] benzodiazepine (D-40tA) and its 1-methyl analogue (D-65MT). Japanese journal of pharmacology, 1971, Volume: 21, Issue:4 Topics: Administration, Oral; Aggression; Animals; Anticonvulsants; Antiemetics; Apomorphine; Avoidance Learning; Azepines; Behavior, Animal; Benzazepines; Cats; Central Nervous System; Chlordiazepoxide; Chlorprothixene; Diazepam; Discrimination Learning; Dogs; Drug Synergism; Female; Haplorhini; Hexobarbital; Humans; Injections, Intraperitoneal; Lethal Dose 50; Male; Mescaline; Methamphetamine; Mice; Morphine; Motor Activity; Muscle Relaxants, Central; Reserpine; Sleep; Tetrabenazine; Triazoles	1971
Synthesis and anxiolytic activity of 6-(substituted-phenyl)-1,2,4-triazolo[4,3-b]pyridazines. Journal of medicinal chemistry, 1981, Volume: 24, Issue:5 Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Antihypertensive Agents; Binding, Competitive; Chemical Phenomena; Chemistry; Conflict, Psychological; Diazepam; Male; Pyridazines; Rats; Triazoles	1981
Detection and determination of active metabolites of 1-(2-o-chlorobenzoyl-4-chlorophenyl)-5-glycyl-aminomethyl-3-dimethy l-carbamoyl-1H-1,2,4-triazole hydrochloride dihydrate, (450191-S), in rat tissues, using a radioreceptor assay for benzodiazepines. Biochemical pharmacology, 1984, May-15, Volume: 33, Issue:10 Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Brain; Diazepam; Hypnotics and Sedatives; Male; Mice; Mice, Inbred Strains; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Time Factors; Triazoles	1984
[Pharmacological studies on drug dependence. (III): Intravenous self-administration of some CNS-affecting drugs and a new sleep-inducer, 1H-1, 2, 4-triazolyl benzophenone derivative (450191-S), in rats]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1984, Volume: 83, Issue:1 Topics: Animals; Central Nervous System Agents; Cocaine; Diazepam; Humans; Hypnotics and Sedatives; Injections, Intravenous; Male; Methamphetamine; Morphine Dependence; Pentazocine; Phenobarbital; Rats; Rats, Inbred Strains; Self Administration; Substance-Related Disorders; Triazoles	1984
2-Benzazepines. 4. [1,2,3]Triazolo[4,5-d][2]benzazepines and dibenzo[c,f][1,2,3]triazolo[3,4-a]azepines: synthesis and evaluation as central nervous system agents. Journal of medicinal chemistry, 1983, Volume: 26, Issue:3 Topics: Animals; Behavior, Animal; Chemical Phenomena; Chemistry; Diazepam; Dibenzazepines; Pentylenetetrazole; Postural Balance; Triazoles	1983
Biochemical evaluations of the effects of loreclezole and propofol on the GABAA receptor in rat brain. Biochemical pharmacology, 1996, Jun-14, Volume: 51, Issue:11 Topics: Anesthetics; Animals; Anticonvulsants; Brain; Bridged Bicyclo Compounds, Heterocyclic; Diazepam; Flunitrazepam; GABA Modulators; gamma-Aminobutyric Acid; Hypnotics and Sedatives; In Vitro Techniques; Male; Muscimol; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sulfur Radioisotopes; Triazoles; Tritium	1996
Pharmacological properties of gamma-aminobutyric acidA receptors from acutely dissociated rat dentate granule cells. Molecular pharmacology, 1996, Volume: 50, Issue:3 Topics: Allosteric Regulation; Animals; Anticonvulsants; Carbolines; Chlorides; Convulsants; Dentate Gyrus; Diazepam; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Hypnotics and Sedatives; In Vitro Techniques; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Triazoles; Zinc Compounds; Zolpidem	1996
Pharmacologic actions of subtype-selective and novel GABAergic ligands in rat lines with differential sensitivity to ethanol. Pharmacology, biochemistry, and behavior, 1996, Volume: 53, Issue:3 Topics: Animals; Autoradiography; Binding, Competitive; Diazepam; Dose-Response Relationship, Drug; Ethanol; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Male; Motor Activity; Pyridines; Rats; Triazoles; Zolpidem	1996
Direct activation of GABAA receptors by loreclezole, an anticonvulsant drug with selectivity for the beta-subunit. Neuropharmacology, 1996, Volume: 35, Issue:12 Topics: Animals; Anticonvulsants; Bicuculline; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Cerebral Cortex; Chloride Channels; Convulsants; Diazepam; DNA, Complementary; Female; gamma-Aminobutyric Acid; Humans; Kinetics; Macromolecular Substances; Male; Membrane Potentials; Oocytes; Picrotoxin; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Recombinant Proteins; Triazoles; Xenopus laevis	1996
GABAA receptor pharmacology and subtype mRNA expression in human neuronal NT2-N cells. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Jul-01, Volume: 18, Issue:13 Topics: Anticonvulsants; Bicuculline; Carbolines; Convulsants; Diazepam; Diuretics; DNA Primers; Furosemide; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Lanthanum; Neurons; Patch-Clamp Techniques; Pentobarbital; Phenobarbital; Picrotoxin; Polymerase Chain Reaction; Pregnanediones; Pregnenolone; Pyridines; Receptors, GABA-A; RNA, Messenger; Teratocarcinoma; Triazoles; Tumor Cells, Cultured; Zinc; Zolpidem	1998
Sensitization by chronic diazepam treatment of A2A adenosine receptor-mediated relaxation in rat pulmonary artery. Life sciences, 1999, Volume: 64, Issue:2 Topics: Adenosine; Animals; Carrier Proteins; Diazepam; Dinucleoside Phosphates; Dipyridamole; Dose-Response Relationship, Drug; Female; Heart; Heart Atria; Muscle Relaxation; Phenethylamines; Pulmonary Artery; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, Purinergic P1; Thioinosine; Triazines; Triazoles; Verapamil	1999
Functional GABAA receptor heterogeneity of acutely dissociated hippocampal CA1 pyramidal cells. Journal of neurophysiology, 1999, Volume: 81, Issue:4 Topics: Allosteric Regulation; Animals; Anticonvulsants; Carbolines; Convulsants; Diazepam; Dose-Response Relationship, Drug; GABA Modulators; gamma-Aminobutyric Acid; Hippocampus; Hypnotics and Sedatives; Membrane Potentials; Patch-Clamp Techniques; Pyramidal Cells; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Triazoles; Zinc; Zolpidem	1999
GABA(A) receptors expressed in undifferentiated human teratocarcinoma NT2 cells differ from those expressed by differentiated NT2-N cells. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Aug-15, Volume: 19, Issue:16 Topics: Anti-Anxiety Agents; Anticonvulsants; Cell Differentiation; Diazepam; Furosemide; Humans; Lanthanum; Neurons; Patch-Clamp Techniques; Pyridines; Receptors, GABA-A; Teratocarcinoma; Triazoles; Tumor Cells, Cultured; Zinc; Zolpidem	1999
The influence of an endogenous beta3 subunit on recombinant GABA(A) receptor assembly and pharmacology in WSS-1 cells and transiently transfected HEK293 cells. Neuropharmacology, 2000, Feb-14, Volume: 39, Issue:4 Topics: Animals; Cell Line; Diazepam; GABA Modulators; Humans; Mice; Patch-Clamp Techniques; Receptors, GABA-A; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transfection; Triazoles	2000
Heterogeneity of GABA(A) receptor-mediated responses in the human IMR-32 neuroblastoma cell line. Journal of neuroscience research, 2000, May-15, Volume: 60, Issue:4 Topics: Anticonvulsants; Bicuculline; Diazepam; Dose-Response Relationship, Drug; GABA Modulators; gamma-Aminobutyric Acid; Humans; Neuroblastoma; Patch-Clamp Techniques; Pentobarbital; Pregnanolone; Protein Isoforms; Receptors, GABA-A; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Triazoles; Tumor Cells, Cultured; Zinc	2000
Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABA(A) receptor alpha1 subtype. Nature neuroscience, 2000, Volume: 3, Issue:6 Topics: Allosteric Site; Animals; Anti-Anxiety Agents; Anticonvulsants; Azides; Benzodiazepines; Binding, Competitive; Brain; Cell Line; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Fluorobenzenes; GABA-A Receptor Antagonists; Hypnotics and Sedatives; Ligands; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Motor Activity; Patch-Clamp Techniques; Receptors, GABA-A; Reflex, Startle; Triazoles	2000
Inhibition of GABA(A) receptor (GABAR) currents by arachidonic acid in HEK 293 cells stably transfected with alpha1beta2gamma2 GABAR subunits. Pflugers Archiv : European journal of physiology, 2000, Volume: 440, Issue:3 Topics: 5,8,11,14-Eicosatetraynoic Acid; Anticonvulsants; Arachidonic Acid; Binding, Competitive; Cells, Cultured; Cyclooxygenase Inhibitors; Diazepam; Dose-Response Relationship, Drug; Fatty Acids; Fatty Acids, Monounsaturated; GABA Antagonists; GABA Modulators; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Indomethacin; Kidney; Linoleic Acid; Masoprocol; Membrane Potentials; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Receptors, GABA-A; Recombinant Proteins; Transfection; Triazoles	2000
Anxiolytic-like action of diazepam: which GABA(A) receptor subtype is involved? Trends in pharmacological sciences, 2001, Volume: 22, Issue:8 Topics: Animals; Anti-Anxiety Agents; Diazepam; Fluorobenzenes; Locomotion; Mice; Point Mutation; Rats; Receptors, GABA-A; Triazoles	2001
Functional characterization of GABA(A) receptors in neonatal hypothalamic brain slice. Journal of neurophysiology, 2002, Volume: 88, Issue:4 Topics: Anesthetics; Animals; Animals, Newborn; Anticonvulsants; Carbolines; Convulsants; Dehydroepiandrosterone Sulfate; Diazepam; Diuretics; Female; Furosemide; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Hypothalamus; Male; Membrane Potentials; Organ Culture Techniques; Patch-Clamp Techniques; Picrotoxin; Pregnanolone; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Triazoles; Zinc; Zolpidem	2002
Design and synthesis of 4H-3-(2-phenoxy)phenyl-1,2,4-triazole derivatives as benzodiazepine receptor agonists. Bioorganic & medicinal chemistry, 2003, Mar-06, Volume: 11, Issue:5 Topics: Animals; Anticonvulsants; Convulsants; Diazepam; Drug Design; GABA-A Receptor Agonists; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mice; Models, Molecular; Molecular Conformation; Pentylenetetrazole; Postural Balance; Seizures; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Triazoles	2003
Effects of benzodiazepines receptor agonists on the hypothalamic-pituitary-adrenocortical axis. European journal of pharmacology, 2005, Sep-20, Volume: 519, Issue:3 Topics: Adrenocorticotropic Hormone; Animals; Azabicyclo Compounds; Carbolines; Corticosterone; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Fluorobenzenes; GABA Agonists; GABA Modulators; GABA-A Receptor Agonists; Hypothalamo-Hypophyseal System; Male; Mice; Mice, Inbred Strains; Models, Biological; Paraventricular Hypothalamic Nucleus; Piperazines; Pituitary-Adrenal System; Proto-Oncogene Proteins c-fos; Pyridines; Radioimmunoassay; Receptors, GABA-A; Triazoles; Zolpidem	2005
High-affinity, slowly desensitizing GABAA receptors mediate tonic inhibition in hippocampal dentate granule cells. Molecular pharmacology, 2006, Volume: 69, Issue:2 Topics: Animals; Anticonvulsants; Dentate Gyrus; Diazepam; Diuretics; Furosemide; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Male; Neural Inhibition; Penicillins; Pyridines; Rats; Rats, Sprague-Dawley; Triazoles; Zolpidem	2006
In vitro blood distribution and plasma protein binding of the iron chelator deferasirox (ICL670) and its iron complex Fe-[ICL670]2 for rat, marmoset, rabbit, mouse, dog, and human. Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:6 Topics: Animals; Benzoates; Binding, Competitive; Callithrix; Deferasirox; Diazepam; Dogs; Female; Ferrous Compounds; Humans; In Vitro Techniques; Iron Chelating Agents; Male; Mice; Protein Binding; Rabbits; Rats; Serum Albumin; Triazoles; Warfarin	2006
Effects of genetic background and null mutation of 5-HT1A receptors on basal and stress-induced body temperature: modulation by serotonergic and GABAA-ergic drugs. European journal of pharmacology, 2006, Nov-21, Volume: 550, Issue:1-3 Topics: Animals; Body Temperature; Body Temperature Regulation; Buspirone; Diazepam; Fever; Flumazenil; Fluorobenzenes; GABA Agonists; GABA Modulators; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pyridines; Receptor, Serotonin, 5-HT1A; Receptors, GABA-A; Serotonin; Serotonin Agents; Serotonin Receptor Agonists; Stress, Psychological; Triazoles; Zolpidem	2006
Reversal of pathological pain through specific spinal GABAA receptor subtypes. Nature, 2008, Jan-17, Volume: 451, Issue:7176 Topics: Analgesics; Animals; Brain; Capsaicin; Chronic Disease; Diazepam; Disease Models, Animal; Fluorobenzenes; Formaldehyde; Ganglia, Spinal; Hot Temperature; Inflammation; Male; Mice; Neurons; Organ Specificity; Pain; Protein Isoforms; Protein Subunits; Rats; Rats, Wistar; Receptors, GABA-A; Spinal Cord; Triazoles	2008
A high-throughput functional assay for characterization of gamma-aminobutyric acid(A) channel modulators using cryopreserved transiently transfected cells. Assay and drug development technologies, 2008, Volume: 6, Issue:6 Topics: Carbolines; Cell Culture Techniques; Cell Line; Cell Membrane; Cryopreservation; Diazepam; DNA; Dose-Response Relationship, Drug; Drug Discovery; Flumazenil; Flunitrazepam; Fluorescent Dyes; Fluorobenzenes; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Membrane Potentials; Receptors, GABA-A; Reproducibility of Results; Spectrometry, Fluorescence; Transfection; Triazoles; Tritium	2008
GABA regulates the rat hypothalamic-pituitary-adrenocortical axis via different GABA-A receptor alpha-subtypes. Annals of the New York Academy of Sciences, 2008, Volume: 1148 Topics: Animals; Brain; Corticotropin-Releasing Hormone; Diazepam; Fluorobenzenes; GABA Agonists; GABA Modulators; gamma-Aminobutyric Acid; Hypothalamo-Hypophyseal System; Male; Neural Pathways; Paraventricular Hypothalamic Nucleus; Pituitary-Adrenal System; Protein Subunits; Proto-Oncogene Proteins c-fos; Pyridines; Random Allocation; Rats; Rats, Wistar; Receptors, GABA-A; Triazoles; Zolpidem	2008
A novel operant conflict procedure using incrementing shock intensities to assess the anxiolytic and anxiogenic effects of drugs. Behavioural pharmacology, 2009, Volume: 20, Issue:3 Topics: Animals; Anti-Anxiety Agents; Anxiety; Aripiprazole; Benzodiazepines; Chlordiazepoxide; Conditioning, Operant; Conflict, Psychological; Dextroamphetamine; Diazepam; Electroshock; Flumazenil; Male; Piperazines; Punishment; Pyridazines; Quinolones; Rats; Rats, Sprague-Dawley; Triazoles; Yohimbine	2009
Alpha1- and alpha2-containing GABAA receptor modulation is not necessary for benzodiazepine-induced hyperphagia. Appetite, 2009, Volume: 52, Issue:3 Topics: Analysis of Variance; Animals; Benzodiazepines; Diazepam; Dose-Response Relationship, Drug; Energy Intake; Female; Fluorobenzenes; GABA Modulators; GABA-A Receptor Agonists; Hyperphagia; Male; Mice; Mice, Knockout; Midazolam; Random Allocation; Receptors, GABA-A; Triazoles	2009
Discriminative stimulus effects of L-838,417 (7-tert-butyl-3-(2,5-difluoro-phenyl)-6-(2-methyl-2H-[1,2,4]triazol-3-ylmethoxy)-[1,2,4]triazolo[4,3-b]pyridazine): role of GABA(A) receptor subtypes. Neuropharmacology, 2010, Volume: 58, Issue:2 Topics: Animals; Barbiturates; Carbolines; Catheterization; Central Nervous System Depressants; Diazepam; Discrimination, Psychological; Dose-Response Relationship, Drug; Ethanol; Flumazenil; Fluorobenzenes; GABA Agonists; GABA Antagonists; GABA Modulators; Neuropsychological Tests; Pyridines; Receptors, GABA-A; Saimiri; Triazoles; Zolpidem	2010
GABA(A) receptor α subunits differentially contribute to diazepam tolerance after chronic treatment. PloS one, 2012, Volume: 7, Issue:8 Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Benzodiazepinones; Body Temperature; Brain; Diazepam; DNA Primers; Drug Tolerance; Flumazenil; Hypnotics and Sedatives; In Situ Hybridization; Male; Mice; Mice, Mutant Strains; Pyridazines; Pyridines; Receptors, GABA-A; Triazoles; Zolpidem	2012
Positive allosteric modulation of GABA-A receptors reduces capsaicin-induced primary and secondary hypersensitivity in rats. Neuropharmacology, 2012, Volume: 63, Issue:8 Topics: Amines; Analgesics, Opioid; Animals; Behavior, Animal; Benzimidazoles; Capsaicin; Cyclohexanecarboxylic Acids; Diazepam; Endpoint Determination; GABA Antagonists; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Pain; Physical Stimulation; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Triazoles	2012
Orexin receptor antagonists differ from standard sleep drugs by promoting sleep at doses that do not disrupt cognition. Science translational medicine, 2013, Apr-03, Volume: 5, Issue:179 Topics: Administration, Oral; Animals; Attention; Azabicyclo Compounds; Choice Behavior; Cognition; Cytoskeletal Proteins; Diazepam; Eszopiclone; gamma-Aminobutyric Acid; Hippocampus; Hypnotics and Sedatives; Macaca mulatta; Male; Memory, Short-Term; Nerve Tissue Proteins; Orexin Receptors; Piperazines; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Recognition, Psychology; Sleep; Task Performance and Analysis; Time Factors; Triazoles; Zolpidem	2013
Allosteric modulation of GABA(A) receptor subtypes:effects on visual recognition and visuospatial working memory in rhesus monkeys [corrected]. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2013, Volume: 38, Issue:11 Topics: Acetamides; Allosteric Regulation; Animals; Benzodiazepines; Conditioning, Operant; Diazepam; Dose-Response Relationship, Drug; Imidazoles; Macaca mulatta; Male; Memory, Short-Term; Pyridazines; Pyridines; Pyrimidines; Receptors, GABA-A; Recognition, Psychology; Triazolam; Triazoles; Zolpidem	2013
Inhibition of Orexin Signaling Promotes Sleep Yet Preserves Salient Arousability in Monkeys. Sleep, 2016, Mar-01, Volume: 39, Issue:3 Topics: Animals; Arousal; Conditioning, Classical; Cross-Over Studies; Diazepam; Eszopiclone; GABA Agents; Hypnotics and Sedatives; Macaca mulatta; Male; Orexin Receptor Antagonists; Orexins; Piperidines; Polysomnography; Signal Transduction; Sleep; Sleep Stages; Triazoles; Wakefulness	2016