diazepam has been researched along with tizanidine in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (25.00) | 18.7374 |
| 1990's | 6 (16.67) | 18.2507 |
| 2000's | 8 (22.22) | 29.6817 |
| 2010's | 13 (36.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Evans, RH; Long, SK; Siarey, RJ | 1 |
| Ishizuki, M; Yanagisawa, M | 1 |
| Dietz, V | 1 |
| Bes, A; Eyssette, M; Pierrot-Deseilligny, E; Rohmer, F; Warter, JM | 1 |
| Igarashi, S; Yamamura, H; Yanagita, T | 1 |
| Fukuda, H; Kato, F; Kato, K; Matsumoto, K; Miyamoto, M; Mori, T; Nakamura, T; Oka, J; Ono, H | 1 |
| Conrad, B; Meinck, HM | 1 |
| Delwaide, PJ | 1 |
| Hennies, OL | 1 |
| Fryda-Kaurimsky, Z; Müller-Fassbender, H | 1 |
| McLellan, DL | 1 |
| Conrad, B; Meinck, HM; Ricker, K | 1 |
| Evans, RH; Long, SK; Siarey, RJ; Tulp, MT | 1 |
| Davis, C; Emre, M; Groves, L; Lataste, X | 1 |
| Fukuda, H; Iwata, N; Kozuka, M; Nakamura, T; Ono, H; Tanabe, M | 1 |
| Goodkin, DE; Kita, M | 1 |
| Patel, DR; Soyode, O | 1 |
| Aisen, M; Ashwal, S; Delgado, MR; Fehlings, DL; Hirtz, D; McLaughlin, J; Morrison, LA; Shrader, MW; Tilton, A; Vargus-Adams, J | 1 |
| Benecke, R; Patejdl, R | 1 |
| Kuks, JB; Lapeyre, E; Meijler, WJ | 1 |
| Delgado, MR; Tilton, A; Vargus-Adams, J | 1 |
| Zdziarski, P | 1 |
| Comi, G; Gold, R; Hartung, HP; Montalban, X; Otero-Romero, S; Sastre-Garriga, J; Soelberg Sørensen, P; Thompson, AJ; Vermersch, P | 1 |
| Kouzouna, A; Lindsay, C; Pandyan, AD; Simcox, C | 1 |
| Fu, X; Li, J; Li, M; Ma, Q; Wang, C; Wang, Y; Wu, H; Yang, W | 1 |
12 review(s) available for diazepam and tizanidine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Spasticity: therapy of increased reflexes or movement disorder?].
Topics: Baclofen; Clonidine; Combined Modality Therapy; Dantrolene; Diazepam; Glycine; Humans; Locomotion; Muscle Relaxants, Central; Muscle Spasticity; Muscle Tonus; Muscles; Phenothiazines; Reflex, Abnormal | 1990 |
Comparative profile of tizanidine in the management of spasticity.
Topics: Activities of Daily Living; Baclofen; Clonidine; Diazepam; Humans; Muscle Relaxants, Central; Muscle Spasticity; Muscle Tonus | 1994 |
Drugs used to treat spasticity.
Topics: Baclofen; Clonidine; Dantrolene; Diazepam; Drug Administration Schedule; Humans; Muscle Relaxants, Central; Muscle Spasticity | 2000 |
Pharmacologic interventions for reducing spasticity in cerebral palsy.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Age Factors; Anti-Infective Agents, Local; Baclofen; Botulinum Toxins; Cerebral Palsy; Child; Child, Preschool; Clonidine; Dantrolene; Diazepam; Ethanol; Humans; Infant; Injections, Intramuscular; Injections, Spinal; Muscle Relaxants, Central; Muscle Spasticity; Neuromuscular Agents; Phenol; Time Factors | 2005 |
Practice parameter: pharmacologic treatment of spasticity in children and adolescents with cerebral palsy (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child
Topics: Adolescent; Botulinum Toxins, Type A; Cerebral Palsy; Child; Clonidine; Diazepam; Humans; Muscle Relaxants, Central; Muscle Spasticity; Neuromuscular Agents; Treatment Outcome | 2010 |
[New therapies for spastic movement disorders].
Topics: Administration, Oral; Baclofen; Botulinum Toxins, Type A; Cannabinoids; Clonidine; Diazepam; Humans; Injections, Intramuscular; Injections, Spinal; Movement Disorders; Muscle Relaxants, Central; Muscle Spasticity; Parasympatholytics; Physical Therapy Modalities; Tolperisone | 2009 |
Spasticity: revisiting the role and the individual value of several pharmacological treatments.
Topics: Amines; Baclofen; Botulinum Toxins; Calcium Channel Blockers; Clonidine; Cyclohexanecarboxylic Acids; Dantrolene; Diazepam; Gabapentin; gamma-Aminobutyric Acid; Humans; Muscle Relaxants, Central; Muscle Spasticity; Recovery of Function; Treatment Outcome | 2010 |
Pharmacologic treatment of spasticity in children.
Topics: Age Factors; Baclofen; Botulinum Toxins; Child; Clonidine; Dantrolene; Diazepam; Humans; Injections, Spinal; Muscle Spasticity; Neuromuscular Agents | 2010 |
Pharmacological management of spasticity in multiple sclerosis: Systematic review and consensus paper.
Topics: Amines; Analgesics; Baclofen; Cannabidiol; Clonidine; Cyclohexanecarboxylic Acids; Dantrolene; Diazepam; Dronabinol; Drug Combinations; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Spinal; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity; Phenol | 2016 |
Pharmacological interventions other than botulinum toxin for spasticity after stroke.
Topics: Baclofen; Botulinum Toxins, Type A; Clonidine; Diazepam; Humans; Muscle Relaxants, Central; Muscle Spasticity; Randomized Controlled Trials as Topic; Stroke; Tolperisone | 2016 |
A mixed treatment comparison on efficacy and safety of treatments for spasticity caused by multiple sclerosis: a systematic review and network meta-analysis.
Topics: Baclofen; Botulinum Toxins, Type A; Cannabinoids; Clonidine; Diazepam; Humans; Multiple Sclerosis; Muscle Relaxants, Central; Muscle Spasticity; Neuromuscular Agents; Transcutaneous Electric Nerve Stimulation | 2018 |
4 trial(s) available for diazepam and tizanidine
| Article | Year |
|---|---|
A multi-centre, double-blind trial of tizanidine, a new antispastic agent, in spasticity associated with hemiplegia.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Clonidine; Diazepam; Double-Blind Method; Female; Hemiplegia; Humans; Male; Middle Aged; Muscle Relaxants, Central; Muscle Spasticity; Random Allocation | 1988 |
Effects of tizanidine in healthy volunteers: double-blind study compared with diazepam and a placebo.
Topics: Adult; Blood Pressure; Clonidine; Diazepam; Double-Blind Method; Heart Rate; Humans; Male; Placebos; Substance-Related Disorders; Surveys and Questionnaires | 1988 |
A new skeletal muscle relaxant (DS 103-282) compared to diazepam in the treatment of muscle spasm of local origin.
Topics: Adult; Aged; Back Pain; Clinical Trials as Topic; Clonidine; Diazepam; Double-Blind Method; Female; Humans; Male; Middle Aged; Muscle Relaxants, Central; Muscle Spasticity | 1981 |
Tizanidine (DS 103-282) in the treatment of acute paravertebral muscle spasm: a controlled trial comparing tizanidine and diazepam.
Topics: Acute Disease; Adult; Back Pain; Clinical Trials as Topic; Clonidine; Diazepam; Double-Blind Method; Female; Humans; Male; Middle Aged; Random Allocation; Spasm; Spinal Diseases; Time Factors | 1981 |
20 other study(ies) available for diazepam and tizanidine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
The effect of centrally acting myorelaxants on NMDA receptor-mediated synaptic transmission in the immature rat spinal cord in vitro.
Topics: Animals; Baclofen; Clonidine; Diazepam; In Vitro Techniques; Muscle Relaxants, Central; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Nerve Roots; Synaptic Transmission; Tetrodotoxin | 1992 |
Antinociceptive effects of tizanidine, diazepam and eperisone in isolated spinal cord-tail preparations of newborn rat.
Topics: Analgesics; Animals; Animals, Newborn; Clonidine; Diazepam; Evoked Potentials; In Vitro Techniques; Muscle Relaxants, Central; Physical Stimulation; Propiophenones; Rats; Rats, Inbred Strains; Reflex; Spinal Cord; Spinal Nerve Roots; Tail; Time Factors | 1992 |
Effects of tizanidine, a centrally acting muscle relaxant, on motor systems.
Topics: Animals; Cerebral Cortex; Chlorpromazine; Clonidine; Decerebrate State; Diazepam; Male; Membranes; Motor Neurons; Muscle Relaxants, Central; Neuromuscular Junction; Neurons, Afferent; Rats; Rats, Inbred Strains; Reflex; Spinal Cord | 1986 |
Neuropharmacological investigations in the stiff-man syndrome.
Topics: Adrenergic Fibers; Central Nervous System Diseases; Clonidine; Diazepam; Female; Humans; Methamphetamine; Muscle Rigidity; Reflex, Abnormal; Reserpine; Syndrome | 1986 |
Electrophysiological analysis of the mode of action of muscle relaxants in spasticity.
Topics: Baclofen; Clonidine; Diazepam; Electrophysiology; Ethanolamines; Female; Humans; Male; Middle Aged; Muscle Relaxants, Central; Muscle Spasticity | 1985 |
The drug treatment of spasticity.
Topics: Baclofen; Clonidine; Dantrolene; Diazepam; Humans; Muscle Spasticity; Parasympatholytics | 1983 |
The stiff-man syndrome: new pathophysiological aspects from abnormal exteroceptive reflexes and the response to clomipramine, clonidine, and tizanidine.
Topics: Adult; Brain Stem; Clomipramine; Clonidine; Diazepam; Electromyography; Female; Humans; Muscle Rigidity; Muscular Diseases; Physical Stimulation; Reflex, Abnormal; Spasm; Syndrome | 1984 |
The effects of central myorelaxants on synaptically-evoked primary afferent depolarization in the immature rat spinal cord in vitro.
Topics: 2-Amino-5-phosphonovalerate; Adrenergic alpha-Agonists; Animals; Baclofen; Clonidine; Diazepam; Electric Stimulation; Evoked Potentials; Ganglia, Spinal; In Vitro Techniques; Muscle Relaxants, Central; Nerve Fibers; Neurons, Afferent; Rats; Receptors, Adrenergic, alpha-2; Spinal Cord; Synapses | 1994 |
Local cerebral glucose utilization in rats with decerebrate rigidity and effects of centrally acting muscle relaxants, diazepam and tizanidine.
Topics: Animals; Cerebellar Nuclei; Clonidine; Decerebrate State; Deoxyglucose; Diazepam; Glucose; Male; Muscle Relaxants, Central; Rats; Rats, Wistar; Vestibular Nuclei | 1993 |
A Case of Stiff Person Syndrome: Immunomodulatory Effect of Benzodiazepines: Successful Rituximab and Tizanidine Therapy.
Topics: Adult; Antibodies, Monoclonal, Murine-Derived; Benzodiazepines; Clonidine; Diazepam; Drug Therapy, Combination; Female; Glutamate Decarboxylase; Humans; Immunologic Factors; Muscle Relaxants, Central; Remission Induction; Rituximab; Stiff-Person Syndrome | 2015 |