diazepam and thyroxine

diazepam has been researched along with thyroxine in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199012 (60.00)18.7374
1990's1 (5.00)18.2507
2000's3 (15.00)29.6817
2010's4 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
El-Hazmi, MA2
Gyermek, L; Henderson, G1
Bird, R; Havard, CW; Saldanha, VF1
Mazzaferri, EL; Skillman, TG1
Blizzard, RM; Czernichow, P; Greenberg, AH1
Hoch, FL; Hogan, FP1
Hoch, FL; Petraitis, FP1
Gillin, JC; Kamgar-Parsi, B; Wehr, TA1
Fuchino, K; Fujii, T; Yamamoto, N1
Cassone, MC; Molinengo, L1
Hack, JB; Hoffman, RS; Leviss, JA; Nelson, LS1
Manley, SW; Mitchell, AM; Mortimer, RH; Powell, KA1
Kimura, T; Matsuzaki, K; Nakagawa, T; Nakanishi, K; Shibukawa, A1
Ishibashi, H; Nabekura, J; Nielsen, M; Witt, MR1

Reviews

1 review(s) available for diazepam and thyroxine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for diazepam and thyroxine

ArticleYear
Diazepam (Valium) and thyroid function: a double-blind, placebo controlled study in normal volunteers showing no drug effect.
    The American journal of the medical sciences, 1969, Volume: 257, Issue:6

    Topics: Adult; Cholesterol; Clinical Trials as Topic; Diazepam; Female; Humans; Hyperthyroidism; Male; Middle Aged; Placebos; Thyroid Function Tests; Thyroid Gland; Thyroxine; Triiodothyronine

1969

Other Studies

18 other study(ies) available for diazepam and thyroxine

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
On the interaction between thyroid hormones and the tranquillisers Librium and Valium.
    Clinica chimica acta; international journal of clinical chemistry, 1975, Sep-01, Volume: 63, Issue:2

    Topics: Animals; Blood Proteins; Chlordiazepoxide; Diazepam; Dose-Response Relationship, Drug; Humans; Male; Rabbits; Thyroid Function Tests; Thyroid Hormones; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine

1975
Low ventilatory and anesthetic drug requirements during myocardial revascularization in a hypothyroid patient.
    Journal of cardiothoracic anesthesia, 1988, Volume: 2, Issue:1

    Topics: Anesthesia, Intravenous; Anesthetics; Coronary Artery Bypass; Coronary Disease; Diazepam; Fentanyl; Humans; Hypothyroidism; Male; Middle Aged; Narcotics; Respiration, Artificial; Sufentanil; Thyroxine

1988
Effect of diazepam (Valium) on dialysable thyroxime.
    Postgraduate medical journal, 1971, Volume: 47, Issue:548

    Topics: Adult; Aged; Dialysis; Diazepam; Female; Humans; Male; Middle Aged; Thyroid Function Tests; Thyroid Gland; Thyroxine

1971
Diazepam (Valium(R)) in thyrotoxicosis. Negative results.
    The Johns Hopkins medical journal, 1970, Volume: 126, Issue:3

    Topics: Adult; Chlordiazepoxide; Cholesterol; Diazepam; Female; Humans; Hyperthyroidism; Iodine Radioisotopes; Radioimmunoassay; Thyroglobulin; Thyroid Function Tests; Thyroid Gland; Thyroxine

1970
Hyperthermia, muscle rigidity, and uncoupling in skeletal muscle mitochondria in rats treated with halothane and 2,4-dinitrophenol.
    Anesthesiology, 1973, Volume: 38, Issue:3

    Topics: Anesthesia, Inhalation; Animals; Body Temperature; Dactinomycin; Diazepam; Dinitrophenols; Drug Synergism; Fever; Halothane; Injections, Intraperitoneal; Magnesium Sulfate; Male; Mitochondria, Liver; Mitochondria, Muscle; Muscle Rigidity; Oxidative Phosphorylation; Oxygen Consumption; Rats; Stimulation, Chemical; Thyroxine; Time Factors

1973
The effect of some sedating agents on calorigenesis and its responses to 2,4-dinitrophenol and L-thyroxine in rats.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 177, Issue:3

    Topics: Animals; Depression, Chemical; Diazepam; Dinitrophenols; Hypnotics and Sedatives; Male; Motor Activity; Oxygen Consumption; Pentobarbital; Rats; Thyroxine; Time Factors; Urethane

1971
Aspects of the interaction of thyroxine and its binding serum proteins with 1,4-benzodiazepine tranquillizers.
    Biochemical medicine, 1981, Volume: 26, Issue:2

    Topics: Anti-Anxiety Agents; Autoradiography; Binding, Competitive; Chlordiazepoxide; Diazepam; Electrophoresis, Polyacrylamide Gel; Humans; Male; Nordazepam; Oxazepam; Temazepam; Thyroxine; Thyroxine-Binding Proteins

1981
Successful treatment of human non-24-hour sleep-wake syndrome.
    Sleep, 1983, Volume: 6, Issue:3

    Topics: Adult; Diazepam; Flurazepam; Humans; Male; Periodicity; Sleep Wake Disorders; Thyroxine; Vitamin B 12

1983
Functional alterations in the hypothalamic-pituitary-thyroid axis in rats exposed prenatally to diazepam.
    Toxicology letters, 1983, Volume: 16, Issue:1-2

    Topics: Animals; Body Weight; Diazepam; Female; Hypothalamo-Hypophyseal System; Male; Pregnancy; Prenatal Exposure Delayed Effects; Radioimmunoassay; Rats; Rats, Inbred Strains; Thyroid Gland; Thyrotropin; Thyroxine

1983
Action of thyroid hormones, diazepam, caffeine and amitriptyline on memory decay ("forgetting").
    Life sciences, 1981, Nov-09, Volume: 29, Issue:19

    Topics: Amitriptyline; Animals; Caffeine; Diazepam; Hyperthyroidism; Hypothyroidism; Male; Memory; Methimazole; Rats; Rats, Inbred Strains; Thyroid Hormones; Thyroxine

1981
Severe symptoms following a massive intentional L-thyroxine ingestion.
    Veterinary and human toxicology, 1999, Volume: 41, Issue:5

    Topics: Adult; Antidotes; Body Weight; Charcoal; Diazepam; Haloperidol; Humans; Intubation, Intratracheal; Male; Phenobarbital; Propranolol; Tachycardia; Thyrotoxicosis; Thyroxine

1999
Different transporters for tri-iodothyronine (T(3)) and thyroxine (T(4)) in the human choriocarcinoma cell line, JAR.
    The Journal of endocrinology, 2000, Volume: 167, Issue:3

    Topics: Analysis of Variance; Biological Transport; Calcium Channel Blockers; Choriocarcinoma; Cyclooxygenase Inhibitors; Diazepam; Female; GABA Modulators; Humans; Iodine Radioisotopes; Leucine; Meclofenamic Acid; Mefenamic Acid; Nifedipine; Nitrendipine; Phenylalanine; Phenytoin; Thyroxine; Triiodothyronine; Tryptophan; Tumor Cells, Cultured; Uterine Neoplasms; Verapamil

2000
High-performance frontal analysis of the binding of thyroxine enantiomers to human serum albumin.
    Pharmaceutical research, 2005, Volume: 22, Issue:4

    Topics: Binding Sites; Binding, Competitive; Chromatography, High Pressure Liquid; Diazepam; Humans; Phenylbutazone; Protein Binding; Serum Albumin; Stereoisomerism; Thyroxine

2005
Modulation of diazepam-insensitive GABA(A) receptors by micromolar concentrations of thyroxine and related compounds in vitro.
    Brain research, 2013, Jan-15, Volume: 1490

    Topics: Affinity Labels; Animals; Azides; Benzodiazepines; Brain; Central Nervous System Depressants; Diazepam; Electrophysiological Phenomena; Ethanol; GABA Modulators; Isoxazoles; Male; Membranes; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, GABA-A; Thyroid Hormones; Thyroxine

2013