Compounds > diazepam

diazepam and thiophenes

diazepam has been researched along with thiophenes in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199010 (66.67)18.7374
1990's1 (6.67)18.2507
2000's2 (13.33)29.6817
2010's2 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Duffy, EM; Jorgensen, WL1
Horikawa, S; Kotorii, M; Nakazawa, Y; Oshima, M; Tachibana, H1
Dicsó, F; Dolinay, T; Hankovszky, E1
Banna, NR; Kurkjian, R1
Corbett, R; Cornfeldt, ML; Dunn, RW; Fielding, S; Laws-Ricker, L; Martin, LL; Payack, JF; Rush, DK; Wilmot, CA1
Eigyo, M; Matsushita, A; Murata, S; Shindo, H; Takada, S1
Chomei, N; Eigyo, M; Kawasaki, K; Matsushita, A; Murata, S; Sasatani, T; Shindo, H; Shintaku, H; Takada, S; Takahara, Y1
Aoki, A; Hagimori, M; Kusumoto, H; Mori, Y; Tanimoto, H1
Miyamoto, S1
Kawasumi, S; Konagaya, K; Sato, K; Takao, K1
Fukuda, T; Kenjo, T; Nakanishi, M; Shuto, S; Takigawa, Y; Tsumagari, T1
Stroman, F; Thiemer, K1
Gruca, P; Litwa, E; Mocaër, E; Papp, M1
Hashimoto, S; Hattori, T; Kasahara, K; Kawakubo, H; Kawasaki, K; Nagatani, T; Nakazono, O; Takao, K; Tsujita, R1
Ahmad, G; Imran, I; Rashid, U; Rasool, N; Rizwan, K; Sadiq, A; Zahoor, AF; Zubair, M1

Trials

4 trial(s) available for diazepam and thiophenes

ArticleYear
Effects of thienodiazepine derivatives on human sleep as compared to those of benzodiazepine derivatives.
    Psychopharmacologia, 1975, Oct-31, Volume: 44, Issue:2

    Topics: Adult; Anti-Anxiety Agents; Azepines; Clinical Trials as Topic; Diazepam; Humans; Male; Nitrazepam; Sleep; Sleep Deprivation; Sleep, REM; Thiophenes; Tranquilizing Agents

1975
[Clinical evaluation of a new minor tranquilizer Y-6047 for the treatment of sleep disturbance on the night before surgery. II. Comparison with diazepam in a double-blind controlled study].
    Masui. The Japanese journal of anesthesiology, 1972, Volume: 21, Issue:3

    Topics: Adolescent; Adult; Aged; Azepines; Clinical Trials as Topic; Diazepam; Female; Humans; Male; Middle Aged; Placebos; Preoperative Care; Sleep Wake Disorders; Thiophenes; Tranquilizing Agents

1972
[Evaluation of a new minor tranquilizer, Y-6047, for preanesthetic medication--comparison with a placebo and diazepam by a double blind controlled study].
    Masui. The Japanese journal of anesthesiology, 1972, Volume: 21, Issue:8

    Topics: Azepines; Clinical Trials as Topic; Diazepam; Evaluation Studies as Topic; Humans; Placebos; Preanesthetic Medication; Thiophenes; Tranquilizing Agents

1972
[Comparison of the effects of minor tranquilizers in preoperative sleep disorders by double blind controlled study].
    Masui. The Japanese journal of anesthesiology, 1972, Volume: 21, Issue:9

    Topics: Azepines; Clinical Trials as Topic; Diazepam; Female; Humans; Male; Nitrazepam; Placebos; Preoperative Care; Sleep Wake Disorders; Thiophenes; Tranquilizing Agents

1972

Other Studies

11 other study(ies) available for diazepam and thiophenes

ArticleYear
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
[Sandosten poisoning in childhood].
    Orvosi hetilap, 1979, Feb-18, Volume: 120, Issue:7

    Topics: Child, Preschool; Diazepam; Drug Therapy, Combination; Female; Furosemide; Gastric Lavage; Histamine H1 Antagonists; Humans; Piperidines; Poisoning; Thiophenes

1979
A novel tremorigen antagonized by D-amphetamine.
    Brain research, 1975, Apr-04, Volume: 87, Issue:1

    Topics: Acetates; Aldehydes; Amines; Animals; Atropine; Calcium; Chlorpromazine; Dextroamphetamine; Diazepam; Diphenhydramine; Ganglionic Stimulants; Histidine; Male; Mice; Oximes; Phenoxybenzamine; Phenytoin; Propranolol; Scopolamine; Thiophenes; Tremor; Trimethadione

1975
Preclinical anxiolytic profiles of 7189 and 8319, novel non-competitive NMDA antagonists.
    Progress in clinical and biological research, 1990, Volume: 361

    Topics: Aniline Compounds; Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Binding, Competitive; Diazepam; Dizocilpine Maleate; Dose-Response Relationship, Drug; Learning; Male; Mice; N-Methylaspartate; Piperazines; Rats; Rats, Inbred Strains; Seizures; Thiophenes; Tritium; Yohimbine

1990
Thienylpyrazoloquinolines with high affinity to benzodiazepine receptors: continuous shift from inverse agonist to agonist properties depending on the size of the alkyl substituent.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:6

    Topics: Animals; Chemical Phenomena; Chemistry; Diazepam; Drug Synergism; Male; Mice; Molecular Structure; Pentylenetetrazole; Pyrazoles; Quinolines; Receptors, GABA-A; Seizures; Structure-Activity Relationship; Thiophenes

1989
Thienylpyrazoloquinolines: potent agonists and inverse agonists to benzodiazepine receptors.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:9

    Topics: Animals; Cerebral Cortex; Chemical Phenomena; Chemistry; Diazepam; Pyrazoles; Quinolines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Structure-Activity Relationship; Thiophenes

1988
Studies on psychotropic drugs. XIX. Psychopharmacological studies of 1-methyl-5-o-chlorophenyl-7-ethyl-1,2-dihydro-3H-thieno(2,3-e)(1,4)diazepin-2-one (Y-6047).
    Arzneimittel-Forschung, 1972, Volume: 22, Issue:11

    Topics: Aggression; Animals; Anticonvulsants; Avoidance Learning; Azepines; Behavior, Animal; Cats; Cerebral Cortex; Chlordiazepoxide; Diazepam; Dogs; Electroencephalography; Female; Haplorhini; Heart; Humans; Hypnotics and Sedatives; Lethal Dose 50; Male; Mice; Motor Activity; Rabbits; Rats; Reflex, Monosynaptic; Thiophenes; Tranquilizing Agents

1972
[Investigations on the general effects of tinofedrine on heart and blood circulation (author's transl)].
    Arzneimittel-Forschung, 1981, Volume: 31, Issue:11

    Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Coronary Circulation; Diazepam; Digoxin; Dogs; Drug Interactions; Heart; Hemodynamics; Regional Blood Flow; Thiophenes

1981
Anxiolytic-like activity of agomelatine and melatonin in three animal models of anxiety.
    Behavioural pharmacology, 2006, Volume: 17, Issue:1

    Topics: Acetamides; Animals; Anti-Anxiety Agents; Arousal; Brain; Buspirone; Chronotherapy; Conditioning, Classical; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Electroshock; Exploratory Behavior; Fear; Male; Maze Learning; Melatonin; Rats; Receptor, Serotonin, 5-HT2C; Receptors, Melatonin; Thiophenes; Vocalization, Animal

2006
The effects of AP521, a novel anxiolytic drug, in three anxiety models and on serotonergic neural transmission in rats.
    Journal of pharmacological sciences, 2015, Volume: 127, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Cells, Cultured; Citalopram; Diazepam; Disease Models, Animal; Drug Synergism; Humans; Isoindoles; Male; Piperazines; Prefrontal Cortex; Pyridines; Pyrimidines; Rats; Receptors, Serotonin; Serotonin; Serotonin 5-HT1 Receptor Agonists; Synaptic Transmission; Thiophenes

2015
Synthesis, in-vitro cholinesterase inhibition, in-vivo anticonvulsant activity and in-silico exploration of N-(4-methylpyridin-2-yl)thiophene-2-carboxamide analogs.
    Bioorganic chemistry, 2019, Volume: 92

    Topics: Acetylcholinesterase; Animals; Anticonvulsants; Butyrylcholinesterase; Cholinesterase Inhibitors; Diazepam; Dose-Response Relationship, Drug; Electrophorus; Female; Horses; Male; Mice; Mice, Inbred BALB C; Molecular Structure; Pentylenetetrazole; Seizures; Structure-Activity Relationship; Thiophenes

2019