diazepam and ranitidine

diazepam has been researched along with ranitidine in 35 studies

Research

Studies (35)

Timeframe	Studies, this research(%)	All Research%
pre-1990	7 (20.00)	18.7374
1990's	4 (11.43)	18.2507
2000's	14 (40.00)	29.6817
2010's	9 (25.71)	24.3611
2020's	1 (2.86)	2.80

Authors

Authors	Studies
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B	1
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Ahman, M; Holmén, AG; Wan, H	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Avdeef, A; Tam, KY	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Artursson, P; Mateus, A; Matsson, P	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Balliano, TL; Barbosa, G; Carvalho, VF; da Silva, BA; de Souza, ET; Lima, LM; Martins, IRR; Martins, MA; Medeiros, MM; Moraes Junior, MO; Nunes, IKDC; Silva, PMR; Silva, SWD	1
Friedman, L; Kadieva, V; Morrell, DF; Roux, A; van Heerden, PV	1
Bouyer, L; Cozian, A; de Dieuleveult, C; Ganansia, MF; Lepage, JY; Malinovsky, JM; Pinaud, M; Rusterholtz, T; Souron, R	2
Arvela, P; Klotz, U; Pasanen, M; Pelkonen, O; Sotaniemi, E	1
Dammann, HG; Gottlieb, W; Keohane, PP; Klotz, U	1
Allo, M; Deutschman, CS; Nicholas, E; Rock, P	1
Hiller, FC; Olsen, KM	1
Klotz, U; Ohnhaus, EE; Reimann, IW	1
Abernethy, DR; Eshelman, FN; Greenblatt, DJ; Shader, RI	1
Kafle, SK; Lekhak, BD; Malla, SM	1
Ebert, AD; Entezami, M; Hopp, HS; Runkel, S; Weitzel, HK	1
Benlloch Petit, R; Gonzalo González, AA; Jarma Antacle, N; Pérez Martínez, D	1

Reviews

1 review(s) available for diazepam and ranitidine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

4 trial(s) available for diazepam and ranitidine

Article	Year
[Comparative effects of diazepam, ranitidine , sodium citrate and enprostil on pH and gastric volume in preanesthetic medication]. Annales francaises d'anesthesie et de reanimation, 1991, Volume: 10, Issue:6 Topics: Antacids; Citrates; Citric Acid; Diazepam; Female; Gastric Juice; Humans; Hydrogen-Ion Concentration; Male; Pneumonia, Aspiration; Preanesthetic Medication; Ranitidine; Risk Factors	1991
Nocturnal doses of ranitidine and nizatidine do not affect the disposition of diazepam. Journal of clinical pharmacology, 1987, Volume: 27, Issue:3 Topics: Adult; Diazepam; Drug Interactions; Histamine H2 Antagonists; Humans; Male; Nizatidine; Nordazepam; Ranitidine; Thiazoles	1987
Ranitidine does not impair oxidative or conjugative metabolism: noninteraction with antipyrine, diazepam, and lorazepam. Clinical pharmacology and therapeutics, 1984, Volume: 35, Issue:2 Topics: Adult; Antipyrine; Biotransformation; Diazepam; Drug Interactions; Humans; Kinetics; Lorazepam; Male; Middle Aged; Random Allocation; Ranitidine	1984
Prophylactic oral ephedrine reduces the incidence of hypotension after subarachnoid block. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1994, Volume: 41, Issue:11 Topics: Abdomen; Administration, Oral; Adult; Anesthesia, Spinal; Blood Pressure; Bupivacaine; Cardiotonic Agents; Diazepam; Ephedrine; Female; Fluid Therapy; Humans; Hypotension; Monitoring, Intraoperative; Nerve Block; Preanesthetic Medication; Premedication; Ranitidine; Subarachnoid Space	1994

Other Studies

30 other study(ies) available for diazepam and ranitidine

Article	Year
Predicting blood-brain barrier permeation from three-dimensional molecular structure. Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11 Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human. European journal of medicinal chemistry, 2009, Volume: 44, Issue:4 Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software	2009
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs. Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability? Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9 Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
A high-throughput cell-based method to predict the unbound drug fraction in the brain. Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7 Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2014
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Discovery of sulfonyl hydrazone derivative as a new selective PDE4A and PDE4D inhibitor by lead-optimization approach on the prototype LASSBio-448: In vitro and in vivo preclinical studies. European journal of medicinal chemistry, 2020, Oct-15, Volume: 204 Topics: Animals; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Drug Design; Enzyme Inhibitors; Humans; Hydrazones; Hypersensitivity; Lung; Male; Mice	2020
Neuromuscular blockade and ventilatory failure after cyclosporine. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1992, Volume: 39, Issue:4 Topics: Cyclosporine; Diazepam; Humans; Kidney Transplantation; Neuromuscular Blocking Agents; Neuromuscular Junction; Ranitidine; Respiratory Insufficiency	1992
[Prophylaxis of Mendelson syndrome with enprostyl (Fundyl)]. Annales francaises d'anesthesie et de reanimation, 1989, Volume: 8 Suppl Topics: Anesthesia; Citrates; Diazepam; Enprostil; Gastric Acid; Humans; Pneumonia, Aspiration; Prostaglandins E, Synthetic; Ranitidine	1989
Effect of five structurally diverse H2-receptor antagonists on drug metabolism. Biochemical pharmacology, 1986, Dec-15, Volume: 35, Issue:24 Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cimetidine; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Diazepam; Famotidine; Histamine H2 Antagonists; Humans; Imidazoles; Kinetics; Male; Microsomes, Liver; Nizatidine; Oxidoreductases; Oxygenases; Pharmaceutical Preparations; Ranitidine; Rats; Rats, Inbred Strains; Thiazoles	1986
Use of esmolol in the intraoperative management of pheochromocytoma. Anesthesia and analgesia, 1988, Volume: 67, Issue:11 Topics: Adrenal Gland Neoplasms; Adrenergic beta-Antagonists; Adult; Diazepam; Female; Hemodynamics; Humans; Intraoperative Complications; Pheochromocytoma; Premedication; Propanolamines; Ranitidine	1988
Management of tetanus. Clinical pharmacy, 1987, Volume: 6, Issue:7 Topics: Aged; Aged, 80 and over; Chlorpromazine; Clostridium tetani; Darkness; Diazepam; Erythromycin; Female; Humans; Intensive Care Units; Middle Aged; Morphine; Ranitidine; Tetanus; Tetanus Toxoid	1987
Effect of ranitidine on the steady state pharmacokinetics of diazepam. European journal of clinical pharmacology, 1983, Volume: 24, Issue:3 Topics: 17-Hydroxycorticosteroids; Adult; Blood Proteins; Diazepam; Drug Interactions; Furans; Humans; Hydrocortisone; Kinetics; Protein Binding; Ranitidine	1983
Acute onset of blindness during labor: report of a case of transient cortical blindness in association with HELLP syndrome. European journal of obstetrics, gynecology, and reproductive biology, 1999, Volume: 84, Issue:1 Topics: Adult; Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Anticonvulsants; Antihypertensive Agents; Apgar Score; Blindness, Cortical; Blood Pressure; Diazepam; Dihydralazine; Electroencephalography; Female; HELLP Syndrome; Histamine H2 Antagonists; Humans; Infant, Newborn; Labor, Obstetric; Liver; Magnesium Sulfate; Magnetic Resonance Imaging; Nimodipine; Prednisolone; Pregnancy; Ranitidine	1999
[Anesthesia in a woman with cold urticaria]. Revista espanola de anestesiologia y reanimacion, 2006, Volume: 53, Issue:9 Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anti-Anxiety Agents; Chlorpheniramine; Cold Temperature; Colectomy; Diazepam; Diverticulum; Female; Histamine H1 Antagonists; Histamine Release; Humans; Intraoperative Complications; Laparoscopy; Middle Aged; Postoperative Complications; Preanesthetic Medication; Ranitidine; Sigmoid Diseases; Urticaria	2006