diazepam has been researched along with pralidoxime in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (19.05) | 18.7374 |
| 1990's | 8 (38.10) | 18.2507 |
| 2000's | 5 (23.81) | 29.6817 |
| 2010's | 4 (19.05) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beasley, VR; Fikes, JD; Parker, AJ; Zachary, JF | 1 |
| Bokonjić, D; Jokanović, M; Jovanović, D; Maksimović, M | 1 |
| Donzanti, BA; Green, MD; Shores, EI | 1 |
| Klemm, WR | 1 |
| Bosković, B; Jovanović, D; Kovacević, V | 1 |
| Koplovitz, I; Stewart, JR | 1 |
| Das Gupta, S; Pant, SC; Vijayaraghavan, R | 1 |
| Beers, ET; Brennecke, LH; Sparenborg, S | 1 |
| Jokanović, M; Maksimović, M | 1 |
| Baubichon, D; Blanchet, G; Brochier, G; Clarencon, D; Galonnier, M; Lallement, G; Mestries, JC | 1 |
| Baubichon, D; Burckhart, MF; Clarençon, D; Galonnier, M; Lallement, G; Masqueliez, C; Mestries, JC; Peoc'h, M | 1 |
| Baubichon, D; Burckhart, MF; Clarençon, D; Galonnier, M; Lallement, G; Peoc'h, M | 1 |
| Baubichon, D; Burckhart, MF; Clarençon, D; Galonnier, M; Jourdil, N; Lallement, G; Peoc'h, M; Renault, F | 1 |
| Breton, P; Buée, J; Calvet, JH; Christin, D; Delamanche, S; Taysse, L | 1 |
| Benjamin, A; McDonough, JH; McMonagle, JD; Rowland, T; Shih, TM | 1 |
| Abbara, C; Bardot, I; Cailleux, A; Clair, P; Diquet, B; Lallement, G; Le Bouil, A; Turcant, A | 1 |
| Abbara, C; Bardot, I; Clair, P; Comets, E; Diquet, B; Lallement, G; Rousseau, JM; Turcant, A | 1 |
| Dillman, JF; Lumley, LA; Meyerhoff, JL; Robison, CL; Spradling, KD | 1 |
| Jacob, J; Tarabar, AF | 1 |
| Blair, RE; Carter, DS; DeLorenzo, RJ; Deshpande, LS; Phillips, KF | 1 |
| DeLorenzo, RJ; Deshpande, LS; Huang, B; Phillips, K | 1 |
1 trial(s) available for diazepam and pralidoxime
| Article | Year |
|---|---|
Bioavailability of diazepam after intramuscular injection of its water-soluble prodrug alone or with atropine-pralidoxime in healthy volunteers.
Topics: Adolescent; Adult; Area Under Curve; Atropine; Biological Availability; Chromatography, High Pressure Liquid; Cross-Over Studies; Diazepam; Dipeptides; Drug Combinations; Humans; Injections, Intramuscular; Male; Middle Aged; Pralidoxime Compounds; Prodrugs; Solubility; Tandem Mass Spectrometry; Water | 2009 |
20 other study(ies) available for diazepam and pralidoxime
| Article | Year |
|---|---|
Clinical, biochemical, electrophysiologic, and histologic assessment of chlorpyrifos induced delayed neuropathy in the cat.
Topics: Animals; Antidotes; Atropine; Carboxylic Ester Hydrolases; Cats; Chlorpyrifos; Cholinesterases; Diazepam; Electromyography; Isoflurophate; Lymphocytes; Male; Motor Neurons; Nervous System Diseases; Neural Conduction; Pralidoxime Compounds; Time Factors | 1992 |
Protective effects of oximes HI-6 and PAM-2 applied by osmotic minipumps in quinalphos-poisoned rats.
Topics: Animals; Antidotes; Atropine; Brain; Cholinesterase Reactivators; Cholinesterases; Diazepam; Insecticides; Lethal Dose 50; Male; Muscles; Organothiophosphorus Compounds; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Rats | 1987 |
Atropine sulfate and 2-pyridine aldoxime methylchloride elicit stress-induced convulsions and lethality in mice and guinea pigs.
Topics: Animals; Atropine; Blood Glucose; Body Temperature; Cold Temperature; Diazepam; Drug Interactions; Guinea Pigs; Male; Mice; Mice, Inbred ICR; Pralidoxime Compounds; Seizures; Species Specificity; Stress, Physiological; Swimming; Time Factors | 1985 |
Efficacy and toxicity of drug combinations in treatment of physostigmine toxicosis.
Topics: Animals; Atropine; Benactyzine; Cholinesterase Reactivators; Diazepam; Drug Therapy, Combination; Ganglionic Blockers; Hexamethonium; Hexamethonium Compounds; Male; Mecamylamine; Mice; Physostigmine; Pralidoxime Compounds; Tranquilizing Agents; Trimedoxime | 1983 |
PAM-2 Cl, HI-6, and HGG-12 in soman and tabun poisoning.
Topics: Acetylcholinesterase; Animals; Antidotes; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diazepam; Dogs; Guinea Pigs; Lethal Dose 50; Male; Mice; Organophosphate Poisoning; Organophosphates; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Rats; Soman; Species Specificity | 1984 |
A comparison of the efficacy of HI6 and 2-PAM against soman, tabun, sarin, and VX in the rabbit.
Topics: Animals; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diazepam; Lethal Dose 50; Male; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Poisoning; Pralidoxime Compounds; Pyridinium Compounds; Pyridostigmine Bromide; Rabbits; Sarin; Soman; Specific Pathogen-Free Organisms | 1994 |
Sarin induced lung pathology and protection by standard therapy regime.
Topics: Animals; Atropine; Cholinesterase Reactivators; Diazepam; Environmental Exposure; Lung; Male; Pralidoxime Compounds; Rats; Sarin | 1993 |
Pharmacological dissociation of the motor and electrical aspects of convulsive status epilepticus induced by the cholinesterase inhibitor soman.
Topics: Analysis of Variance; Animals; Antidotes; Atropine; Brain; Cholinesterase Inhibitors; Diazepam; Electroencephalography; Guinea Pigs; Image Processing, Computer-Assisted; Male; Pralidoxime Compounds; Pyridostigmine Bromide; Scopolamine; Soman; Status Epilepticus | 1993 |
A comparison of trimedoxime, obidoxime, pralidoxime and HI-6 in the treatment of oral organophosphorus insecticide poisoning in the rat.
Topics: Administration, Oral; Animals; Antidotes; Atropine; Diazepam; Dose-Response Relationship, Drug; Insecticides; Male; Obidoxime Chloride; Organophosphorus Compounds; Oximes; Pralidoxime Compounds; Rats; Rats, Wistar; Trimedoxime | 1995 |
Efficacy of atropine/pralidoxime/diazepam or atropine/HI-6/prodiazepam in primates intoxicated by soman.
Topics: Animals; Antidotes; Atropine; Cholinesterase Inhibitors; Diazepam; Dipeptides; Drug Therapy, Combination; Electrocardiography; Electroencephalography; Macaca fascicularis; Male; Oximes; Poisoning; Pralidoxime Compounds; Prodrugs; Pyridinium Compounds; Soman | 1997 |
Nerve agent poisoning in primates: antilethal, anti-epileptic and neuroprotective effects of GK-11.
Topics: Animals; Anticonvulsants; Atropine; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Cyclohexanes; Cyclohexenes; Diazepam; Drug Combinations; Excitatory Amino Acid Antagonists; Injections, Intravenous; Macaca fascicularis; Male; Muscarinic Antagonists; Neuroprotective Agents; Piperidines; Pralidoxime Compounds; Seizures; Soman; Staining and Labeling; Time Factors | 1998 |
Acute soman poisoning in primates neither pretreated nor receiving immediate therapy: value of gacyclidine (GK-11) in delayed medical support.
Topics: Animals; Anticonvulsants; Antidotes; Atropine; Brain; Cerebellum; Cerebral Cortex; Chemical Warfare Agents; Cholinesterase Reactivators; Cyclohexanes; Cyclohexenes; Diazepam; Drug Therapy, Combination; Electrocardiography; Excitatory Amino Acid Antagonists; Haplorhini; Macaca fascicularis; Male; Piperidines; Poisoning; Pralidoxime Compounds; Seizures; Soman; Time Factors | 1999 |
Compared efficacy of diazepam or avizafone to prevent soman-induced electroencephalographic disturbances and neuropathology in primates: relationship to plasmatic benzodiazepine pharmacokinetics.
Topics: Animals; Atropine; Brain; Cholinesterase Inhibitors; Diazepam; Dipeptides; Drug Therapy, Combination; Electroencephalography; Macaca fascicularis; Male; Pralidoxime Compounds; Soman | 2000 |
Comparative efficacy of diazepam and avizafone against sarin-induced neuropathology and respiratory failure in guinea pigs: influence of atropine dose.
Topics: Animals; Anticonvulsants; Atropine; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Diazepam; Dipeptides; Drug Interactions; Electroencephalography; Guinea Pigs; Histocytochemistry; Muscarinic Antagonists; Nervous System Diseases; Pralidoxime Compounds; Prodrugs; Pyridostigmine Bromide; Respiratory Insufficiency; Sarin; Seizures | 2003 |
Effects of fosphenytoin on nerve agent-induced status epilepticus.
Topics: Animals; Anticonvulsants; Atropine; Chemical Warfare Agents; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Guinea Pigs; Injections, Intraperitoneal; Male; Phenytoin; Pralidoxime Compounds; Pyridostigmine Bromide; Soman; Status Epilepticus | 2004 |
High-performance liquid chromatography coupled with electrospray tandem mass spectrometry (LC/MS/MS) method for the simultaneous determination of diazepam, atropine and pralidoxime in human plasma.
Topics: Atropine; Chromatography, High Pressure Liquid; Diazepam; Humans; Pralidoxime Compounds; Reproducibility of Results; Tandem Mass Spectrometry | 2008 |
Transcriptional analysis of rat piriform cortex following exposure to the organophosphonate anticholinesterase sarin and induction of seizures.
Topics: Animals; Anticonvulsants; Atropine; Brain; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diazepam; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Humans; Male; Microarray Analysis; Muscarinic Antagonists; Pralidoxime Compounds; Principal Component Analysis; Rats; Rats, Sprague-Dawley; Sarin; Seizures; Signal Transduction; Transcription, Genetic | 2011 |
A rare case of combined strychnine and propoxur toxicity from a single preparation.
Topics: Adult; Atropine; Charcoal; Diazepam; Drug Combinations; Gastric Lavage; Humans; Insecticides; Intubation, Gastrointestinal; Male; Midazolam; Poisoning; Poisons; Pralidoxime Compounds; Propoxur; Spasm; Strychnine; Suicide, Attempted | 2012 |
Development of status epilepticus, sustained calcium elevations and neuronal injury in a rat survival model of lethal paraoxon intoxication.
Topics: Animals; Anticonvulsants; Atropine; Brain; Calcium; Diazepam; Disease Models, Animal; Electroencephalography; Hippocampus; Male; Neurons; Organophosphate Poisoning; Paraoxon; Pralidoxime Compounds; Rats; Rats, Sprague-Dawley; Status Epilepticus | 2014 |
Chronic behavioral and cognitive deficits in a rat survival model of paraoxon toxicity.
Topics: Anhedonia; Animals; Anxiety; Atropine; Behavior, Animal; Cognition Disorders; Depression; Diazepam; Male; Memory Disorders; Organophosphate Poisoning; Paraoxon; Pralidoxime Compounds; Rats; Rats, Sprague-Dawley; Recognition, Psychology | 2014 |