diazepam has been researched along with oxazepam in 403 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 263 (65.26) | 18.7374 |
| 1990's | 43 (10.67) | 18.2507 |
| 2000's | 35 (8.68) | 29.6817 |
| 2010's | 55 (13.65) | 24.3611 |
| 2020's | 7 (1.74) | 2.80 |
| Authors | Studies |
|---|---|
| Collins, RJ; Gall, M; Kamdar, BV | 1 |
| Blazević, N; Kajfez, F; Kolbah, D; Kovac, T; Sunjić, V | 1 |
| Babbini, M; Barbaro, AM; Bartoletti, M; Biagi, GL; Borea, PA; Gaiardi, M; Guerra, MC | 1 |
| Johnston, GA; Maddalena, DJ | 1 |
| Karplus, M; So, SS | 1 |
| Ghuloum, AM; Jain, AN; Sage, CR | 1 |
| Coassolo, P; Lavé, T; Schneider, G | 1 |
| Carrupt, PA; Crivori, P; Cruciani, G; Testa, B | 1 |
| Duffy, EM; Jorgensen, WL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Ertl, P; Rohde, B; Selzer, P | 1 |
| Artursson, P; Luthman, K; Norinder, U; Stenberg, P | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Chang, TK; Ensom, MH; Kiang, TK | 1 |
| Caron, G; Ermondi, G | 1 |
| Carrupt, PA; Martel, S; Ottaviani, G | 1 |
| Du-Cuny, L; Huwyler, J; Kansy, M; Wiese, M | 1 |
| Briand, X; Faller, B; Lázaro, E; Lowe, PJ | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Azzara, AV; Baska, RA; Behnia, K; Carlson, KE; Cullen, MJ; Devenny, JJ; Ellsworth, BA; Everlof, GG; Ewing, WR; Godonis, HE; Gu, Z; Gudmundsson, O; Harvey, SJ; Johnghar, S; Kang, L; Keim, WJ; Lee, N; Murphy, BJ; Murugesan, N; Pelleymounter, MA; Ranasinghe, A; Rohrbach, KW; Sher, PM; Sitkoff, DF; Stetsko, PI; Sulsky, RB; Thomas, MA; Wu, G; Wu, X; Yang, Y; Yu, G; Zhu, Y; Zuvich, E | 1 |
| Artursson, P; Mateus, A; Matsson, P | 1 |
| Deng, Y; Li, Y; Liu, Q; Qiang, X; Sang, Z; Tan, Z; Xiao, G | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Deng, Y; Li, Y; Luo, L; Qiang, X; Tan, Z; Xiao, G | 1 |
| Cao, Z; Deng, Y; Li, Y; Luo, L; Qiang, X; Sang, Z; Su, F; Xiao, G; Yang, X; Zheng, Y | 1 |
| Ai, J; Deng, Y; Li, Y; Liu, Q; Luo, L; Qiang, X; Tan, Z; Xiao, G; Yang, X | 1 |
| Cao, Z; Deng, Y; Li, Y; Luo, L; Qiang, X; Sang, Z; Su, F; Xiao, G; Xu, R; Yang, X; Zheng, Y | 1 |
| Cao, Z; Deng, Y; Li, Y; Luo, L; Qiang, X; Tan, Z; Xu, R; Yang, X; Zheng, Y | 1 |
| Cao, Z; Deng, Y; Li, Y; Luo, L; Qiang, X; Song, Q; Tan, Z; Xiao, G; Xu, R; Yang, X | 1 |
| Bai, P; Leng, C; Li, X; Liu, W; Ma, Q; Pan, W; Sang, Z; Tan, Z; Wang, K; Xu, Q; Yang, Y; Yu, L | 1 |
| Liu, W; Ma, Q; Pan, W; Sang, Z; Wang, K; Yu, L | 1 |
| Han, X; Liu, W; Ma, Q; Sang, Z; Wang, H; Wang, K; Ye, M; Yu, L | 2 |
| Cao, Z; Deng, Y; Li, Y; Liu, H; Qiang, X; Song, Q; Tan, Z; Xu, R; Yang, J; Zhang, X | 1 |
| Deng, Y; Li, Y; Liu, H; Song, Q; Tan, Z; Xiao, G; Xu, R; Yang, Z; Zhang, X; Zheng, Y | 1 |
| Ganeshpurkar, A; Gupta, SK; Gutti, G; Krishnamurthy, S; Kumar, D; Modi, G; Singh, SK | 1 |
| An, Q; Deng, Y; Liu, P; Luo, Y; Sang, Z; Tang, Y; Wang, T; Yang, T; Yang, Y; Zhang, T | 1 |
| Cao, Z; Deng, Y; Li, Y; Liu, H; Qiang, X; Song, Q; Tan, Z; Tian, C; Yang, Z | 1 |
| Rai, SN; Shankar, S; Sharma, P; Shrivastava, SK; Singh, SP; Srivastava, P; Srivastava, RK; Tripathi, PN | 1 |
| Deng, Y; He, Y; Li, W; Liu, H; Qiang, X; Song, Q; Tan, Z; Ye, C | 1 |
| Liu, W; Sang, Z; Shi, J; Tan, Z; Wang, K | 1 |
| Liu, W; Sang, Z; Shi, J; Tan, Z; Wang, K; Zhang, P | 1 |
| Fan, X; Liu, W; Sang, Z; Shi, J; Wang, K; Yang, D; Zhang, P; Zhang, Z; Zhu, G | 1 |
| Bai, P; Cheng, X; Cheng, Y; Lu, X; Sang, Z; Shi, J; Wang, K; Yang, J; Zhang, P; Zhang, Q; Zheng, C | 1 |
| Bajusz, D; Balogh, GT; Dargó, G; Müller, J; Simon, K | 1 |
| Carmona, AV; Kumari, S; Tiwari, AK; Trippier, PC | 1 |
| Jaiswal, S; Raja Ayyannan, S; Tiwari, V; Uniyal, A | 1 |
| Bourgoin, S; Hanson, M; Héry, F; Ternaux, JP | 1 |
| Davis, DC; Holtzman, SG; Shannon, HE | 1 |
| Golovenko, NIa; Zin'kovskii, VG | 1 |
| Solomon, K | 1 |
| Erkkola, R; Kangas, L; Kanto, J; Piiroinen, O | 1 |
| Aliverti, V; Mariani, L | 1 |
| Pilbrant, A; Sundwall, A; Vessman, J; Wretlind, M | 1 |
| Han, WW; Maness, DD; Yakatan, GJ | 1 |
| Greenblatt, DJ; Shader, RI | 7 |
| Carrigan, PJ; Chun, AH; Hoffman, DJ; Kershner, RP; Stuart, JD | 1 |
| Medvedev, OS; Val'dman, AV | 1 |
| Kozlovskaia, MM; Val'dman, AV | 1 |
| Solomon, D | 1 |
| Hoyumpa, AM | 1 |
| Billings, BJ; Giles, HG; Greenblatt, DJ; MacLeod, SM; Marshman, JA; Martin, PR; Sellers, EM | 1 |
| Schenker, S | 1 |
| Deinum, EJ; Ifabumuyi, OI; Kazarian, SS; Merskey, H; Tekatch, GM | 1 |
| Wilkinson, GR | 1 |
| Hunt, P; Husson, JM; Raynaud, JP | 1 |
| Baars, AM; Hekster, YA; O'Reilly, WJ; van der Kleijn, E; Vree, TB | 1 |
| Schmid, A | 1 |
| Donaldson, D; Drury, KA; Rutherford, D; Spalding, E | 1 |
| Borzecki, Z; Jarzebowski, E; Rejowska, J; Swies, Z | 1 |
| Stone, BM | 1 |
| Azcarate, CL | 1 |
| Caliari, S; Romano, A; Scrollini, F; Torchio, P | 1 |
| Albanus, L; Jönsson, M; Sparf, B | 1 |
| Keeler, MH; Miller, WC | 1 |
| Kabra, PM; Marton, LJ; Stevens, GL | 1 |
| Haataja, M; Hurme, P; Kanto, J; Sellman, R | 1 |
| Allen, MD; Greenblatt, DJ; Orsulak, PJ; Shader, RI; Woo, E | 1 |
| Clarke, CH; Nicholson, AN | 1 |
| Sun, SR | 1 |
| Klotz, U | 1 |
| Andersson, BE; Götestam, KG | 1 |
| Garattini, S | 1 |
| Hovi-Viander, M; Iisalo, EU; Kangas, L; Kanto, J | 1 |
| Cohen, ME; Duffner, PK; Jusko, WJ; MacKichan, JJ | 1 |
| Kanto, J; Mäenpää, M; Mäntylä, R; Sellman, R; Valovirta, E | 1 |
| Aderjan, R; Schmidt, G | 1 |
| Sellers, EM; Wong, GB | 1 |
| Greenblatt, DJ; Woo, E | 1 |
| Nicholson, AN | 1 |
| Dostálová, K; Hrbek, J; Komenda, S; Macáková, J; Siroká, A | 1 |
| McAllister, CB | 1 |
| Owen, F; Waddington, JL | 1 |
| Nicholson, AN; Stone, BM | 1 |
| Kaistha, KK; Tadrus, R | 1 |
| Linnoila, M; Mattila, MJ; Palva, ES | 1 |
| Cassano, GB; Morselli, PL; Pacifici, GM; Placidi, GF; Tognoni, G | 1 |
| Duvhök, C; Molander, L | 1 |
| Holtzman, SG; Shannon, HE | 1 |
| Blackwell, B | 2 |
| Greenblatt, DJ; Koch-Weser, J; Shader, RI | 1 |
| Comi, V; Gervasi, GB; Trebbi, A | 1 |
| Azcarate, CL; Koepke, HH; Lion, JR | 1 |
| Kangas, L; Kanto, J; Siirtola, T | 1 |
| Cavallin-Stähl, E; Lundh, B; Mercke, C | 1 |
| Haerten, K; Pöttgen, W | 1 |
| Jablońska, JK; Knobloch, K; Majka, J; Wiśniewska-Knypl, JM | 1 |
| Lorenzo, B; Monforte, JR; Sunshine, I; Valentour, JC | 1 |
| Kanto, J | 1 |
| Forsström, J; Iisalo, E; Kangas, L; Kanto, J | 1 |
| Inaba, T; Mahon, WA; Stone, R; Tsutsumi, E; Umeda, T | 1 |
| Sellers, EM; Sullivan, JT | 1 |
| Hagberg, G; Laegreid, L; Lundberg, A | 1 |
| Furuie, MA; Hibino, S; Maruyama, T; Otagiri, M | 1 |
| Hönack, D; Löscher, W | 1 |
| Loeffler, PM | 1 |
| Constant, H; Duthel, JM; Miachon, S; Rochet, T; Vallon, JJ | 1 |
| Lewis, DC; Sullivan, JT; Swift, RM | 1 |
| Gifford, E; Johnson, M; Tsai, CC | 1 |
| Martin, WR; Sloan, JW; Wala, EP | 2 |
| Guentert, TW; Stebler, T | 1 |
| Daubländer, M; Lipp, M | 1 |
| Greenblatt, DJ; Sethy, VH | 1 |
| Wong, PT | 1 |
| Dusci, LJ; Good, SM; Hall, RW; Ilett, KF | 1 |
| Odar-Cederlöf, I; Säwe, J; von Bahr, C; Yue, Q | 1 |
| Kuznetsova, NI; Sukhodolova, GI | 1 |
| Kuznetsova, NI | 1 |
| Chenery, RJ; Lockwood, GF; Seddon, T | 1 |
| Fujimura, T; Furusawa, S; Sasaki, K; Takayanagi, Y | 1 |
| Ciancio, SG | 1 |
| McDevitt, DG | 1 |
| Oberholzer, DJ | 1 |
| Bollen, EL; Bruinvels, J; Ketelaars, CE; Rigter, H | 1 |
| Igarashi, T; Kitagawa, H; Ohmori, S; Okiyama, M; Ueno, K | 3 |
| Beletskaia, IO; Devoĭno, LV | 1 |
| Klockowski, PM; Levy, G | 2 |
| Ghoneim, MM; Hinrichs, JV; Mewaldt, SP | 2 |
| Brase, DA; Dewey, WL; Glennon, RA; Young, R | 1 |
| Busto, U; Cappell, H; Naranjo, CA; Sanchez-Craig, M; Sellers, EM; Sykora, K | 1 |
| Alazia, M; Cano, JP; Crevat-Pisano, P; Drouet, C; Francois, G; Lacarelle, B | 1 |
| Kanto, J; Scheinin, M | 1 |
| Bareggi, SR; Ferrario, P; Pirola, R; Zecca, L | 1 |
| Martin, WR; McNicholas, LF; Sloan, JW; Wala, E | 1 |
| Kennedy, S; O'Brien, DP; Pellis, SM; Pellis, VC; Teitelbaum, P; Wolgin, DL | 1 |
| Jørgensen, NP; Thurmann-Nielsen, E; Walstad, RA | 1 |
| Abdel-Hamid, ME; Abuirjeie, MA | 1 |
| Billings, RF; Hersch, EL | 1 |
| Bergman, U; Griffiths, RR | 1 |
| Diwan, BA; Rice, JM; Ward, JM | 1 |
| Brown, C; File, SE; Greenblatt, DJ; Martin, IL | 1 |
| Moroji, T; Motomura, H; Noguchi, T; Sekiguchi, R; Tada, K | 1 |
| Berwish, NJ; Bond, WS; Swift, B | 1 |
| Martin, WR; McNicholas, LF; Pruitt, TA | 1 |
| Fitos, I; Lagercrantz, C; Larsson, T; Simonyi, M; Sjöholm, I; Tegyey, Z | 1 |
| Czyzewska-Szafran, H; Wutkiewicz, M | 1 |
| Cascorbi, HF | 1 |
| Barrett, J; Davidson, IE; Smyth, WF | 1 |
| Hailey, DM | 2 |
| Aleksandrovskiĭ, IuA; But, PG; Chibrikin, VM; Kaplunskiĭ, GD; poltorakov, AP | 1 |
| Gogolák, G; Liebeswar, G; Stumpf, C | 1 |
| Browne, TR; Penry, JK | 1 |
| Hartmann-von Monakow, K | 1 |
| Müller, W; Wollert, U | 1 |
| Jenkins, RW; Stevens, HM | 1 |
| Aleksandrovskiĭ, IuA; Bragina, NN; Fleĭs, EP | 1 |
| Crowley, HJ; Dalton, C; Schallek, W; Sheppard, H | 1 |
| Schultz, J | 3 |
| Gluckman, MI | 2 |
| Fanelli, R; Kvetina, J; Marcucci, F | 1 |
| Vinar, O | 1 |
| Gardner-Thorpe, C; Parsonage, MJ; Toothill, C | 1 |
| Iisalo, E; Kanto, J; Lehtinen, V; Salminen, J | 1 |
| Erkkola, R; Kanto, J; Sellman, R | 2 |
| de Angelis, L; Traversa, U; Vertua, R | 1 |
| Danneberg, P; Knappen, F; Minck, K | 1 |
| Boissier, JR; Schoonhoed, L; Simon, P; Soubrie, P; Wlodaver, C | 1 |
| Naess, K | 1 |
| Birnbaum, D; Karmeli, F | 1 |
| Katz, RL | 1 |
| Hollister, LE | 1 |
| Prokudin, VN | 1 |
| Broeren, W | 1 |
| Weber, DJ | 1 |
| Heubel, F; Patutschnick, H | 1 |
| Linford, W | 1 |
| Hedlund, U; Marcusson, J | 1 |
| Zingales, IA | 1 |
| Nolan, NA; Parkes, MW | 1 |
| McMillan, DE | 1 |
| Braithwaite, RA; Silverman, G | 1 |
| Cardini, C; Stacchini, A | 1 |
| Boissier, JR; Simon, P; Soubrié, P; Thiébot, MH | 1 |
| Besner, JG; Caillé, G; Dugal, R; Plaa, G | 1 |
| Kallal, TJ; Kohn, FE; Sennello, LT | 1 |
| Hegedic, Z; Pürgyi, P | 1 |
| Hailey, DM; Howard, AG; Nickless, G | 1 |
| Iisalo, EU; Kanto, JH; Pihlajamaki, KK | 1 |
| Marcy, R; Quermonne, MA | 1 |
| Bliding, A | 1 |
| Dundee, JW; Haslett, WH | 1 |
| Retterstol, N | 1 |
| Hrbek, J; Komenda, S; Macáková, J; Siroká, A | 1 |
| Holmberg, G; Livstedt, B | 1 |
| Beelen, GC; Frederick, MA; van der Kleijn, E | 1 |
| Biscaldi, GP; Hattab, J; Montanaro, N; Scoz, R | 1 |
| Fanelli, R; Garattini, S; Marcucci, F; Mussini, E | 6 |
| Bertagni, P; Garattini, S; Marcucci, F; Mussini, E | 1 |
| Dzhagatspanian, IA; Klygul', TA; Vikhliaev, IuI | 1 |
| Bjondahl, K; Haataja, M; Kangas, L; Möttönen, M; Nieminen, L | 1 |
| Garattini, S; Guaitani, A; Marcucci, F | 1 |
| Beer, B; Clody, DE; Vogel, JR | 1 |
| Collard, J | 1 |
| Fanelli, R; Forgione, A; Jommi, GC; Marcucci, F; Martelli, P; Mussini, E | 1 |
| Shader, RI | 1 |
| Berry, DJ | 1 |
| Lafargue, P; Lemontey, Y; Meunier, J | 1 |
| Hattori, K; Matsuda, K; Murata, H; Yasumura, A | 1 |
| Fanelli, R; Garattini, S; Guaitani, A; Marcucci, F; Mussini, E | 1 |
| Perez de Francisco, C | 1 |
| Beyer, KH; Sadée, W | 1 |
| Gurney, BF | 1 |
| Bader, G; De Silva, JA; Koechlin, BA | 1 |
| Saslavsky, Z | 1 |
| Babbini, M; De Marchi, F; Montanaro, N; Strocchi, P; Torrielli, MV | 1 |
| Mascherpa, P | 1 |
| Garattini, S; Marcucci, F; Mussini, E | 1 |
| Agersborg, HP; Owen, G; Smith, TH | 1 |
| Longoni, A; Pessotti, I | 1 |
| Hrbek, J; Komenda, S; Medek, A; Navrátil, J | 1 |
| adée, W | 1 |
| Christmas, AJ; Maxwell, DR | 1 |
| Yoshino, T | 1 |
| Malick, JB | 1 |
| Lafargue, P; Meunier, J; Pont, P | 1 |
| Carbone, JJ; Schwartz, MA | 1 |
| Carbone, JJ; Cheripko, JA; Coutinho, CB | 1 |
| Aleksandrovskiĭ, IuA | 1 |
| López Nogueira, JM | 1 |
| Sawada, H; Shinohara, K | 1 |
| Bauen, A; Possanza, GJ | 1 |
| Katz, MH; Krop, S; Yen, HC | 1 |
| Sadée, W; Van der Kleijn, E | 1 |
| Adronati, SA; Klygul', TA; Prokudin, VN; Vikhliaev, IuI | 1 |
| Babbini, M; Gaiardi, M; Montanaro, N; Strocchi, P | 1 |
| De Marchi, F; Graziani, G | 1 |
| Dolce, G | 1 |
| de Carolis, AS; Longo, VG | 1 |
| Bechtoldt, AA; Berman, L; Murray, WJ | 1 |
| Postma, E; Schwartz, MA | 1 |
| Fanelli, R; Marcucci, F; Mussini, E | 1 |
| Garattini, S; Guaitani, A; Kvetina, J; Marcucci, F; Mussini, E | 1 |
| Beckstead, HD; Smith, SJ | 1 |
| Arrigo, A; Mille, T; Pastorino, G | 1 |
| Alburn, HE; Lee, JM; Ruelius, HW | 1 |
| Ban, TA | 1 |
| Davituliani, D; Koreli, A | 1 |
| Cohen, ES; Holman, RC | 1 |
| Meeles, MT; Thys, CP; Tjaden, UR; van der Kaay, M | 1 |
| Forster, J; Patten, DW; Rosser, WW; Simms, JG | 1 |
| Harms, D; Nechvatal, D; Pachale, E | 2 |
| Lapierre, YD | 1 |
| Ruffalo, RL; Segal, JL; Thompson, JF | 1 |
| Vozeh, S | 1 |
| El-Hazmi, MA | 1 |
| Rosser, WW | 1 |
| Kanto, JH | 1 |
| Berthe, J; Gouy, D; Mazue, G; Remandet, B; Roncucci, R; Williams, GM | 1 |
| Löscher, W | 1 |
| MacKinnon, GL; Parker, WA | 1 |
| Furusawa, S; Monma, K; Sasaki, K; Takayanagi, G | 1 |
| Berlin, RM; Conell, LJ | 1 |
| Furusawa, S; Sasaki, K; Takayanagi, G | 1 |
| Kaniewska, T | 1 |
| Fasching, I; Haubenstock, A; Hruby, K; Jäger, U | 1 |
| Johnson, HD; Male, CG | 1 |
| Olive, G; Rey, E | 1 |
| Kobayashi, H; Saito, H; Sakai, T; Takeno, S | 1 |
| Gonzalez, JP; McCulloch, AJ; Nicholls, PJ; Sewell, RD; Tekle, A | 1 |
| Klinger, W; Müller, D; Richter, K; Wierzba, W | 1 |
| Ator, NA; Bigelow, GE; Brady, JV; Griffiths, RR; Higgins, ST; Liebson, IA; Lucas, SE; Stitzer, ML | 1 |
| Agrawal, KK; Gupta, A; Tayal, G; Tekur, U | 1 |
| Booij, LH; Crul, JF; Driessen, JJ; van Egmond, J; Vree, TB | 1 |
| Bigelow, GE; Griffiths, RR; Liebson, IA; McLeod, DR; Roache, JD | 1 |
| Aranko, K; Aranko, S; Mattila, MJ; Seppälä, T | 1 |
| Bigelow, GE; Griffiths, RR; Liebson, IA; Roache, JD | 1 |
| DeVane, CL; Stewart, RB | 1 |
| Bigelow, GE; Griffiths, RR; Liebson, IA; McLeod, DR; Nowowieski, P; Roache, JD | 1 |
| Coffman, WB; McFarland, SA; Meyer, EA; Mumford, R; Wynn, RL | 1 |
| Klotz, U; Reimann, I | 1 |
| Dixon, R | 1 |
| Frey, HH; Löscher, W | 1 |
| Greenblatt, DJ; Harmatz, JS; Salzman, C; Shader, RI | 1 |
| Kulik, AV; Wilbur, R | 1 |
| Hekster, CA; van der Kleijn, E; Vree, TB | 1 |
| Kardos, J; Maksay, G; Otvös, L; Simonyi, M; Tegyey, Z | 1 |
| Chiba, K; Chiba, T; Hirano, T; Horii, H; Ishizaki, T; Kato, Y | 1 |
| Jenck, F; Martin, JR; Moreau, JL | 1 |
| Needleman, SB; Porvaznik, M | 1 |
| Cohen, SI | 1 |
| Dale, O; Mortensen, B | 1 |
| Gajewska, M; Goldnik, A; Jaworska, M | 1 |
| Pang, KS; St-Pierre, MV | 1 |
| Friedman, LS; Mayo-Smith, MF; Saitz, R | 1 |
| Alcorn, J; Papich, MG | 1 |
| Banerjee, S; Giri, AK | 1 |
| Sloan, JW; Wala, EP | 1 |
| Hapke, HJ; Klaus, AM; Shini, S | 1 |
| Mattila, MJ; Mattila-Evenden, ME | 1 |
| Jing, X; Sloan, JW; Wala, EP | 1 |
| Ali, HM; Azzam, RM; Notarianni, LJ | 1 |
| Berman, ME; Taylor, SP; Weisman, AM | 1 |
| Ackermann, I; Angermaier, L; Deinl, I; Franzelius, C; Machbert, G | 1 |
| Blanc, F; Butterworth, RF; Fabbro-Peray, P; Lavoie, J; Layrargues, GP; Mousseau, DD; Perney, P | 1 |
| Hemmersbach, P; Ragnar Norli, H; Rasmussen, KE; Reubsaet, KJ | 1 |
| Böhmer, C; Centelles, JJ; Kinne, RK; Palmada, M | 1 |
| Dolejsová, J; Efstathiou, CE; Koupparis, MA; Polydorou, CK; Solich, P | 1 |
| Collins, DC; Lee, ML | 1 |
| Mørland, J; Olsen, KM; Skuterud, B; Smith-Kielland, A | 1 |
| Contel, N; Grossman, S; Liu, Z; Ren, S; Rose, A; Short, J; Unger, S | 1 |
| Centelles, JJ; Kinne, RK; Kinne-Saffran, E; Palmada, M | 1 |
| Gasparini, F; Gentsch, C; Kuhn, R; Schoeffter, P; Spooren, WP | 1 |
| Baas, JM; Böcker, KB; Brack, AA; Grillon, C; Kenemans, JL; Morgan, CA; Verbaten, MN | 1 |
| Djeridane, Y; Touitou, Y | 1 |
| Bicz, W; Kobylińska, K; Pachecka, J; Zagdańska, B; Zasłona, H | 1 |
| Atta-Politou, J; Panderi, I; Valavani, P | 1 |
| Ahlner, J; Bengtsson, F; Prochazka, J; Reis, M; Sitsen, A | 1 |
| Musteata, FM; Musteata, ML; Pawliszyn, J | 1 |
| Draper, A; Leonard, N; Ogilvie, BW; Parkinson, A | 1 |
| Dickson, SJ; Irving, RC | 1 |
| Juvonen, R; Korhonen, LE; Pelkonen, O; Raunio, H; Tolonen, A; Turpeinen, M; Uusitalo, J | 1 |
| Bouchonnet, S; Kinani, S; Milan, N; Ricordel, I | 1 |
| Lamas, E; Pellón, R; Rodríguez, C; Ruíz, A | 1 |
| Hengster, P; Hermann, M; Libiseller, K; Margreiter, R; Pavlic, M; Wurm, M | 1 |
| Durand Alegría, JS; Fernández Hernando, P; Gil Tejedor, AM | 1 |
| Acikgöz, A; Bader, A; Giri, S; Karim, N; Schmidt-Heck, W | 1 |
| Dai, Z; Liang, X; Liu, W | 1 |
| Iannello, C; Mandrioli, R; Matrisciano, F; Mercolini, L; Nicoletti, F; Raggi, MA | 1 |
| Chronister, CW; Goldberger, BA; Merves, ML | 1 |
| Acikgöz, A; Bader, A; Giri, S; Maringka, M; Nieber, K | 1 |
| Mariani, CL; Musulin, SE; Papich, MG | 1 |
| KuKanich, B; Nauss, JL | 1 |
| Heath, E; Kompare, B; Kosjek, T; Landeka Dragičević, T; Perko, S; Zanoški Hren, M; Zigon, D; Zupanc, M | 1 |
| Liang, C; Ni, C; Rao, Y; Wang, R; Wang, X; Xiong, L; Zhang, Y | 1 |
| Atayee, RS; Best, BM; Luk, S; Ma, JD | 1 |
| Gogol, M; Hartmann, H; Simm, A; Wustmann, S | 1 |
| Bertol, E; Boscolo Berto, R; Favretto, D; Mannaioni, G; Mari, F; Vaiano, F | 1 |
| Cui, YL; He, X; Liu, J; Shan, WC; Wang, JP; Zhang, L | 1 |
| Bankstahl, M; Gramer, M; Hausknecht, M; Klein, S; Löscher, W | 1 |
| Li, J; Liu, H; Wu, L; Zhang, J | 1 |
| Hsu, MH; Huang, CW; Iqbal, U; Jian, WS; Li, YJ; Nguyen, PA; Syed-Abdul, S; Yang, HC; Yen, Y | 1 |
| McKeown, DA; O'Connor, LC; Torrance, HJ | 1 |
| Bjørner, T; Skomedal, T; Tvete, IF | 1 |
| Darwish, WS; Hayami, A; Ikenaka, Y; Ishizuka, M; Kawai, YK; Mizukawa, H; Nakayama, SM; Watanabe, KP | 1 |
| Buckley, NA; Cairns, R; Pearson, SA; Schaffer, AL | 1 |
| Jia, J; Jiang, F; Johansen, SS; Linnet, K; Rao, Y; Wang, X; Zhang, Y | 1 |
| Mangelings, D; Muscat Galea, C; Vander Heyden, Y | 1 |
| Castro, A; Costa, P; Franco, JM; Melo, P; Quintas, MJ; Tarelho, S; Teixeira, HM | 1 |
| Boxho, P; Charlier, C; Denooz, R; Dubois, N; Lemaire, E; Schmidt, C | 1 |
| Bugelli, V; Campobasso, CP; Chericoni, S; Fornaro, S; Giusiani, M; Papi, L; Stefanelli, F; Vanin, S | 1 |
| Azuar, J; Barreteau, H; Bellivier, F; Bloch, V; Declèves, X; Dereux, A; Fortias, M; Grichy, L; Lépine, JP; Martinez, L; Questel, F; Vorspan, F | 1 |
| Jongen, S; Ramaekers, JG; Vermeeren, A; Vuurman, EFPM | 1 |
| Alizadeh, R; Salami, M; Seidi, S | 1 |
| Jørgensen, MB; Osler, M | 1 |
| Falcon, M; Fernadez-Lopez, L; Luna, A; Mancini, R; Pellegrini, M; Rotolo, M | 1 |
| Johannsen, ML; Jørgensen, FS; Munkboel, CH; Styrishave, B | 1 |
| Hansen, KB; Knudsen, ST; Mäkinen, VN | 1 |
28 review(s) available for diazepam and oxazepam
| Article | Year |
|---|---|
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Amide Bond Bioisosteres: Strategies, Synthesis, and Successes.
Topics: Amides; Carbamates; Click Chemistry; Drug Design; Pyridines; Structure-Activity Relationship; Triazoles; Urea | 2020 |
Benzodiazepines and neurotic anxiety. Critique.
Topics: Aggression; Animals; Anti-Anxiety Agents; Anxiety; Behavior; Behavior, Animal; Chemical Phenomena; Chemistry; Chlordiazepoxide; Clinical Trials as Topic; Clorazepate Dipotassium; Diazepam; Humans; Kinetics; Lethal Dose 50; Oxazepam; Psychiatric Status Rating Scales | 1976 |
Minor tranquilizers in the treatment of aggression.
Topics: Aggression; Animals; Anti-Anxiety Agents; Anxiety; Chlordiazepoxide; Depression; Diazepam; Epilepsy; Female; Humans; Hypochondriasis; Male; Mental Disorders; Meprobamate; Mice; Neurocognitive Disorders; Oxazepam; Psychophysiologic Disorders; Rage; Schizoid Personality Disorder; Schizophrenia | 1975 |
Selection among benzodiazepines for alcohol withdrawal.
Topics: Administration, Oral; Benzodiazepines; Central Nervous System; Chlordiazepoxide; Clorazepate Dipotassium; Depression, Chemical; Diazepam; Drug Synergism; Ethanol; Half-Life; Humans; Oxazepam; Seizures; Substance Withdrawal Syndrome; Time Factors | 1977 |
[Clinical pharmacokinetics of diazepam and its biologically active metabolites (author's transl)].
Topics: Biotransformation; Diazepam; Half-Life; Humans; Kinetics; Models, Biological; Nordazepam; Oxazepam | 1978 |
Biochemical and pharmacological properties of oxazepam.
Topics: Acetylcholine; Aggression; Animals; Anticonvulsants; Behavior, Animal; Brain; Chemical Phenomena; Chemistry; Diazepam; Guinea Pigs; Humans; Isomerism; Mice; Oxazepam; Rats | 1978 |
A critical review of oxazepam: efficacy and specificity.
Topics: Age Factors; Aged; Chlordiazepoxide; Clinical Trials as Topic; Diazepam; Disorders of Excessive Somnolence; Humans; Oxazepam; Placebos | 1975 |
Pharmacokinetics in clinical medicine: oxazepam versus other benzodiazepines.
Topics: Administration, Oral; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Humans; Injections, Intravenous; Male; Mathematics; Models, Biological; Oxazepam; Time Factors | 1975 |
Oral benzodiazepines and conscious sedation: a review.
Topics: Administration, Oral; Alprazolam; Ambulatory Surgical Procedures; Anti-Anxiety Agents; Conscious Sedation; Diazepam; Flurazepam; Humans; Lorazepam; Midazolam; Oxazepam; Premedication; Receptors, GABA-A; Temazepam; Triazolam | 1992 |
A sound basis for the use of benzodiazepines.
Topics: Anesthesia; Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Drug Utilization; Epilepsy; Humans; Injections, Intravenous; Nervous System Diseases; Oxazepam | 1985 |
Biotransformation of drugs used in anesthesia.
Topics: Acetates; Anesthetics; Animals; Atropine; Biotransformation; Carbon Tetrachloride; Chloroform; Diazepam; Drug Interactions; Ethers; Fentanyl; Halothane; Humans; Lidocaine; Liver; Lung; Mepivacaine; Methoxyflurane; Oxazepam; Pharmacogenetics | 1973 |
Drug therapy. Benzodiazepines (first of two parts).
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Antidepressive Agents; Behavior, Animal; Biotransformation; Blood Circulation; Carboxylic Acids; Chlordiazepoxide; Costs and Cost Analysis; Diazepam; Flurazepam; Humans; Limbic System; Muscles; Oxazepam; Respiration; Structure-Activity Relationship | 1974 |
Chromatography of the 1,4-benzodiazepines.
Topics: Anti-Anxiety Agents; Chlordiazepoxide; Chromatography; Diazepam; Flurazepam; Humans; Methylation; Nitrazepam; Oxazepam; Oxazoles; Prazepam; Solvents; Spectrometry, Fluorescence; Temperature | 1974 |
Benzodiazepines in the treatment of epilepsy. A review.
Topics: Adult; Animals; Anticonvulsants; Chlordiazepoxide; Diazepam; Disease Models, Animal; Eclampsia; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Humans; Infant; Light; Myoclonus; Nitrazepam; Oxazepam; Pentylenetetrazole; Pregnancy; Seizures; Substance Withdrawal Syndrome | 1973 |
The clinical choice of sedative-hypnotics.
Topics: Animals; Anticoagulants; Barbiturates; Chloral Hydrate; Chlordiazepoxide; Chlorpromazine; Diazepam; Drug Interactions; Enzyme Induction; Ethchlorvynol; Glutethimide; Guinea Pigs; Humans; Hypnotics and Sedatives; Meprobamate; Methaqualone; Oxazepam; Phenindione; Rats; Sleep, REM; Tranquilizing Agents | 1972 |
[Psychopharmaca in modern medicine].
Topics: Amphetamine; Antidepressive Agents; Barbiturates; Butyrophenones; Chlordiazepoxide; Chlorprothixene; Diazepam; Dibenzazepines; Guaifenesin; Hallucinogens; Humans; Hypnotics and Sedatives; Imipramine; Lithium; Lysergic Acid Diethylamide; Methylphenidate; Monoamine Oxidase Inhibitors; Oxazepam; Phenmetrazine; Phenothiazines; Phytotherapy; Piperidines; Plants, Medicinal; Psilocybin; Psychopharmacology; Rauwolfia; Reserpine; Tranquilizing Agents; Xanthenes | 1968 |
Sedatives and tranquilizers.
Topics: Anxiety; Barbiturates; Chlordiazepoxide; Clinical Trials as Topic; Diazepam; Humans; Hypnotics and Sedatives; Meprobamate; Oxazepam; Placebos; Substance-Related Disorders | 1972 |
[Features of the clinical effect of benzodiazepine derivatives (according to the findings of comparative studies). Review of the literature].
Topics: Adjustment Disorders; Aggression; Animals; Antisocial Personality Disorder; Barbiturates; Benzazepines; Brain Diseases; Chlordiazepoxide; Depression; Diazepam; Drug Synergism; Epilepsy; Humans; Neurotic Disorders; Nitrazepam; Oxazepam; Rabbits; Schizophrenia; Tranquilizing Agents | 1973 |
The benzodiazepines. A review of their actions and uses relative to anaesthetic practice.
Topics: Amnesia; Anesthesia; Anesthesia, Intravenous; Anesthesia, Obstetrical; Anticonvulsants; Benzazepines; Cardiovascular System; Chlordiazepoxide; Dentistry; Depression, Chemical; Diazepam; Endoscopy; Female; Humans; Maternal-Fetal Exchange; Muscle Relaxants, Central; Oxazepam; Postoperative Care; Preanesthetic Medication; Pregnancy; Respiration; Spasm | 1970 |
[Misuse of benzodiazepine derivatives. A review, with special reference to Norwegian data].
Topics: Chlordiazepoxide; Diazepam; Humans; Norway; Oxazepam; Substance-Related Disorders; Tranquilizing Agents | 1971 |
Diazepam-cimetidine drug interaction: a clinically significant effect.
Topics: Anti-Anxiety Agents; Cimetidine; Cytochrome P-450 Enzyme System; Depression, Chemical; Diazepam; Drug Interactions; Guanidines; Humans; Kinetics; Lorazepam; Oxazepam; Oxidation-Reduction | 1981 |
Use of benzodiazepines during pregnancy, labour and lactation, with particular reference to pharmacokinetic considerations.
Topics: Anti-Anxiety Agents; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Female; Flunitrazepam; Humans; Infant, Newborn; Labor, Obstetric; Lactation; Lorazepam; Maternal-Fetal Exchange; Nitrazepam; Oxazepam; Pregnancy | 1982 |
Benzodiazepine withdrawal syndrome: a literature review and evaluation.
Topics: Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Dose-Response Relationship, Drug; Humans; Lorazepam; Nitrazepam; Oxazepam; Substance Withdrawal Syndrome; Substance-Related Disorders; Temazepam; Time Factors | 1982 |
The use of benzodiazepines in clinical practice.
Topics: Anti-Anxiety Agents; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Humans; Kinetics; Lorazepam; Metabolic Clearance Rate; Oxazepam; Prazepam; Substance Withdrawal Syndrome | 1981 |
[Benzodiazepines and pregnancy. Transplacental passage, labor and lactation].
Topics: Anti-Anxiety Agents; Biotransformation; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Female; Flunitrazepam; Humans; Kinetics; Lorazepam; Maternal-Fetal Exchange; Milk, Human; Nitrazepam; Oxazepam; Postpartum Period; Pregnancy | 1983 |
Genetic toxicology of four commonly used benzodiazepines: a review.
Topics: Animals; Benzodiazepines; Chlordiazepoxide; Diazepam; DNA Damage; Humans; Mutagenicity Tests; Mutagens; Nitrazepam; Oxazepam | 1996 |
35 trial(s) available for diazepam and oxazepam
| Article | Year |
|---|---|
Benzodiazepines and neurotic anxiety. Critique.
Topics: Aggression; Animals; Anti-Anxiety Agents; Anxiety; Behavior; Behavior, Animal; Chemical Phenomena; Chemistry; Chlordiazepoxide; Clinical Trials as Topic; Clorazepate Dipotassium; Diazepam; Humans; Kinetics; Lethal Dose 50; Oxazepam; Psychiatric Status Rating Scales | 1976 |
Effect of antacids on absorption of clorazepate.
Topics: Adult; Aluminum Hydroxide; Antacids; Anti-Anxiety Agents; Biopharmaceutics; Clorazepate Dipotassium; Diazepam; Half-Life; Humans; Magnesium Hydroxide; Male; Middle Aged; Oxazepam | 1977 |
Immediate and residual effects in man of the metabolites of diazepam.
Topics: Adult; Choice Behavior; Diazepam; Humans; Male; Motor Skills; Nordazepam; Oxazepam; Placebos; Reaction Time; Temazepam; Time Factors | 1978 |
Subjective effects and vigilance after diazepam and oxazepam in normal subjects.
Topics: Attention; Autonomic Nervous System; Clinical Trials as Topic; Diazepam; Double-Blind Method; Drug Evaluation; Efficiency; Female; Humans; Male; Oxazepam; Placebos | 1978 |
A comparative study on the clinical effects of oxazepam and diazepam: Relationship between plasma level and effect.
Topics: Adult; Biotransformation; Child; Clinical Trials as Topic; Diazepam; Female; Humans; Male; Middle Aged; Oxazepam; Preanesthetic Medication | 1979 |
Hypnotic activity of 3-hydroxy, N-desmethyldiazepam (oxazepam).
Topics: Adult; Diazepam; Electroencephalography; Humans; Hypnotics and Sedatives; Male; Oxazepam; Placebos; Sleep; Time Factors | 1978 |
Effect of active metabolites of chlordiazepoxide and diazepam, alone or in combination with alcohol, on psychomotor skills related to driving.
Topics: Adult; Alcoholic Intoxication; Attention; Automobile Driving; Chlordiazepoxide; Clinical Trials as Topic; Diazepam; Drug Interactions; Ethanol; Female; Humans; Male; Motor Skills; Oxazepam; Placebos; Reaction Time | 1976 |
A critical review of oxazepam: efficacy and specificity.
Topics: Age Factors; Aged; Chlordiazepoxide; Clinical Trials as Topic; Diazepam; Disorders of Excessive Somnolence; Humans; Oxazepam; Placebos | 1975 |
Heme catabolism during short-term treatment with phenobarbital, diazepam and oxazepam.
Topics: Adult; Bilirubin; Carbon Monoxide; Depression, Chemical; Diazepam; Heme; Hemoglobins; Humans; Male; Oxazepam; Phenobarbital; Stimulation, Chemical; Time Factors | 1975 |
Beta-blockers and psychometric performance: studies in normal volunteers.
Topics: Adrenergic beta-Antagonists; Atenolol; Diazepam; Dose-Response Relationship, Drug; Humans; Lipid Metabolism; Nadolol; Oxazepam; Propanolamines; Propranolol; Psychometrics; Psychomotor Performance; Random Allocation; Reaction Time; Reference Values; Solubility; Time Factors | 1985 |
The behavioral actions of diazepam and oxazepam are similar.
Topics: Adolescent; Adult; Affect; Behavior; Diazepam; Double-Blind Method; Female; Humans; Learning; Male; Memory; Mental Recall; Oxazepam; Psychomotor Performance; Random Allocation | 1986 |
Withdrawal reaction after long-term therapeutic use of benzodiazepines.
Topics: Adolescent; Adult; Aged; Anxiety; Benzodiazepines; Diazepam; Double-Blind Method; Female; Flurazepam; Humans; Long-Term Care; Lorazepam; Male; Middle Aged; Oxazepam; Patient Compliance; Placebos; Substance Withdrawal Syndrome; Time Factors | 1986 |
Comparison of two benzodiazepines with differing accumulation: behavioral changes during and after 3 weeks of dosing.
Topics: Administration, Oral; Adult; Analysis of Variance; Diazepam; Double-Blind Method; Drug Tolerance; Female; Half-Life; Humans; Male; Memory; Mental Recall; Oxazepam; Psychomotor Performance; Random Allocation | 1986 |
Sedatives and tranquilizers.
Topics: Anxiety; Barbiturates; Chlordiazepoxide; Clinical Trials as Topic; Diazepam; Humans; Hypnotics and Sedatives; Meprobamate; Oxazepam; Placebos; Substance-Related Disorders | 1972 |
[Prudent use of drugs against anxiety].
Topics: Anxiety; Chemical Phenomena; Chemistry; Depression; Diazepam; Evaluation Studies as Topic; Humans; Hypnotics and Sedatives; Meprobamate; Oxazepam; Personality; Phenobarbital; Physician-Patient Relations; Placebos; Secobarbital | 1973 |
Effects of different rates of absorption of two benzodiazepins on subjective and objective parameters. Significance for clinical use and risk of abuse.
Topics: Absorption; Anxiety; Diazepam; Female; Hand; Humans; Male; Oxazepam; Placebos; Pulse; Reaction Time; Sleep Wake Disorders; Substance-Related Disorders; Time Factors; Tremor | 1974 |
Acute effect of medazepam (15 mg), oxazepam (20 mg) and diazepam (10 mg) on verbal associations.
Topics: Adult; Association; Benzazepines; Brain; Clinical Trials as Topic; Diazepam; Female; Hearing; Humans; Male; Oxazepam; Placebos; Psychophysiology; Speech; Time Factors; Touch; Tranquilizing Agents; Verbal Learning; Vision, Ocular; Word Association Tests | 1971 |
[Continuing flicker fusion research with sedatives including fenemal].
Topics: Clinical Trials as Topic; Diazepam; Flicker Fusion; Humans; Oxazepam; Phenobarbital; Placebos; Time Factors | 1971 |
Quantitative polygraphic evaluation of emotional tension in the study of a new benzodiazepine.
Topics: Benzazepines; Diazepam; Emotions; Humans; Oxazepam; Sympathetic Nervous System | 1971 |
Meprobamate: a study of irrational drug use.
Topics: Agranulocytosis; Anemia, Aplastic; Anxiety; Chlordiazepoxide; Diazepam; Humans; Meprobamate; Neurotic Disorders; Oxazepam; Placebos; Purpura; Substance-Related Disorders; Suicide; Thrombocytopenia | 1971 |
Blood level distribution patterns of diazepam and its major metabolite in man.
Topics: Chromatography, Gas; Chromatography, Thin Layer; Clinical Trials as Topic; Delayed-Action Preparations; Diazepam; Drug Tolerance; Humans; Injections, Intramuscular; Injections, Intravenous; Male; Middle Aged; Oxazepam; Spectrophotometry; Ultraviolet Rays | 1966 |
Efficacy of oral psychosedative drugs for preanesthetic medication.
Topics: Adult; Age Factors; Anxiety; Body Weight; Diazepam; Ethchlorvynol; Female; Humans; Hydroxyzine; Hypnotics and Sedatives; Male; Oxazepam; Pentobarbital; Placebos; Preanesthetic Medication; Sex Factors; Tranquilizing Agents | 1968 |
[Vigilance and beta blockade. The influence of the beta blocker atenolol and other substances on the reaction time of the visual system].
Topics: Adrenergic beta-Antagonists; Adult; Amphetamines; Atenolol; Attention; Diazepam; Humans; Male; Oxazepam; Propanolamines; Reaction Time; Theophylline; Visual Perception | 1981 |
Influence of the beta-blocking atenolol and other medications on visual reaction time.
Topics: Adult; Amphetamines; Atenolol; Central Nervous System Stimulants; Diazepam; Drug Interactions; Ethanol; Humans; Male; Oxazepam; Propanolamines; Reaction Time; Theophylline; Time Factors; Vision, Ocular | 1981 |
Oral benzodiazepine premedication in minor gynaecological surgery.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Benzodiazepinones; Clinical Trials as Topic; Clobazam; Diazepam; Double-Blind Method; Female; Flicker Fusion; Humans; Lorazepam; Mental Recall; Middle Aged; Oxazepam; Preanesthetic Medication; Reaction Time; Sleep Stages; Surgical Procedures, Operative | 1984 |
Relative abuse liability of diazepam and oxazepam: behavioral and subjective dose effects.
Topics: Adult; Behavior; Cognition; Diazepam; Dose-Response Relationship, Drug; Drug Tolerance; Emotions; Humans; Male; Middle Aged; Oxazepam; Psychomotor Performance; Sleep; Substance-Related Disorders; Time Factors | 1984 |
Long v short half-life benzodiazepines in the elderly. Kinetics and clinical effects of diazepam and oxazepam.
Topics: Age Factors; Aged; Diazepam; Double-Blind Method; Fatigue; Female; Half-Life; Humans; Kinetics; Male; Middle Aged; Oxazepam; Sleep Stages | 1983 |
Absorption of diazepam after its rectal administration in dogs.
Topics: Absorption; Administration, Rectal; Animals; Anticonvulsants; Chromatography, High Pressure Liquid; Cross-Over Studies; Diazepam; Dogs; Dose-Response Relationship, Drug; Fluorescence Polarization Immunoassay; Injections, Intravenous; Male; Nordazepam; Oxazepam; Time Factors | 1995 |
Effects of alcohol and hypnosedative drugs on digit-symbol substitution: comparison of two different computerized tests.
Topics: Adult; Central Nervous System Depressants; Computers; Cross-Over Studies; Diazepam; Double-Blind Method; Ethanol; Female; Humans; Hypnotics and Sedatives; Male; Oxazepam; Psychological Tests; Psychomotor Performance | 1997 |
Effects of clorazepate, diazepam, and oxazepam on a laboratory measurement of aggression in men.
Topics: Adult; Aggression; Anti-Anxiety Agents; Clorazepate Dipotassium; Diazepam; Double-Blind Method; Humans; Male; Oxazepam; Reaction Time | 1998 |
Urinary excretion of diazepam metabolites in healthy volunteers and drug users.
Topics: Adult; Anti-Anxiety Agents; Chromatography, Gas; Chromatography, High Pressure Liquid; Creatinine; Diazepam; Female; Humans; Male; Middle Aged; Nordazepam; Oxazepam; Substance Abuse Detection; Substance-Related Disorders; Temazepam | 2001 |
Benzodiazepines have no effect on fear-potentiated startle in humans.
Topics: Adolescent; Adult; Analysis of Variance; Anti-Anxiety Agents; Anxiety; Diazepam; Dose-Response Relationship, Drug; Double-Blind Method; Electromyography; Electroshock; Fear; Female; Habituation, Psychophysiologic; Humans; Male; Oxazepam; Photic Stimulation; Psychiatric Status Rating Scales; Psychomotor Performance; Reflex, Startle | 2002 |
Inter- and intraindividual pharmacokinetic variations of mirtazapine and its N-demethyl metabolite in patients treated for major depressive disorder: a 6-month therapeutic drug monitoring study.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Body Size; Chromatography, High Pressure Liquid; Depressive Disorder, Major; Diazepam; Dose-Response Relationship, Drug; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Male; Mianserin; Mirtazapine; Outpatients; Oxazepam; Prospective Studies; Sex Factors; Smoking; Time Factors; Treatment Refusal | 2005 |
Diazepam pharmacokinetics after nasal drop and atomized nasal administration in dogs.
Topics: Administration, Intranasal; Animals; Anticonvulsants; Diazepam; Dogs; Dosage Forms; Drug Administration Routes; Female; Half-Life; Male; Nordazepam; Oxazepam | 2011 |
Comparing the effects of oxazepam and diazepam in actual highway driving and neurocognitive test performance: a validation study.
Topics: Adult; Attention; Automobile Driving; Cognition; Cross-Over Studies; Diazepam; Double-Blind Method; Female; Healthy Volunteers; Humans; Hypnotics and Sedatives; Male; Mental Status and Dementia Tests; Middle Aged; Oxazepam; Psychomotor Performance; Young Adult | 2018 |
343 other study(ies) available for diazepam and oxazepam
| Article | Year |
|---|---|
Pharmacology of some metabolites of triazolam, alprazolam, and diazepam prepared by a simple, one-step oxidation of benzodiazepines.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Diazepam; Hydroxylation; Male; Methods; Mice; Oxidation-Reduction; Triazolam; Triazoles | 1978 |
Synthesis of some carbon-3 substituted 1,4-benzodiazepin-2-ones and their central nervous system effects.
Topics: Animals; Benzodiazepinones; Central Nervous System; Esters; Ethers; Female; Male; Mice; Solubility | 1979 |
Rm values and structure-activity relationship of benzodiazepines.
Topics: Animals; Benzodiazepines; Chromatography, Thin Layer; Conflict, Psychological; Exploratory Behavior; Models, Biological; Rats; Solubility; Structure-Activity Relationship | 1980 |
Prediction of receptor properties and binding affinity of ligands to benzodiazepine/GABAA receptors using artificial neural networks.
Topics: Binding Sites; Ligands; Neural Networks, Computer; Predictive Value of Tests; Receptors, GABA-A; Structure-Activity Relationship | 1995 |
Genetic neural networks for quantitative structure-activity relationships: improvements and application of benzodiazepine affinity for benzodiazepine/GABAA receptors.
Topics: Algorithms; Benzodiazepines; Models, Genetic; Nerve Net; Protein Binding; Receptors, GABA-A; Structure-Activity Relationship | 1996 |
Molecular hashkeys: a novel method for molecular characterization and its application for predicting important pharmaceutical properties of molecules.
Topics: Drug Design; Intestinal Absorption; Models, Molecular; Pharmaceutical Preparations; Structure-Activity Relationship | 1999 |
Combining in vitro and in vivo pharmacokinetic data for prediction of hepatic drug clearance in humans by artificial neural networks and multivariate statistical techniques.
Topics: Animals; Biological Availability; Dogs; Humans; Least-Squares Analysis; Liver; Multivariate Analysis; Neural Networks, Computer; Pharmacokinetics; Rats | 1999 |
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Fast calculation of molecular polar surface area as a sum of fragment-based contributions and its application to the prediction of drug transport properties.
Topics: Biological Availability; Biological Transport; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Reproducibility of Results | 2000 |
Experimental and computational screening models for the prediction of intestinal drug absorption.
Topics: Biological Transport; Carbon Radioisotopes; Cell Line; Cell Membrane; Cell Membrane Permeability; Ciprofloxacin; Computational Biology; Drug Design; Foscarnet; Humans; Hydrogen Bonding; Intestinal Absorption; Intestinal Mucosa; Lactulose; Mannitol; Models, Biological; Raffinose; Surface Properties; Tritium; Verapamil | 2001 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities.
Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water | 2007 |
Computational aqueous solubility prediction for drug-like compounds in congeneric series.
Topics: Benzodiazepines; Computer Simulation; Crystallography, X-Ray; Databases, Factual; Least-Squares Analysis; Models, Chemical; Organic Chemicals; Pharmaceutical Preparations; Principal Component Analysis; Solubility; Sulfonamides; Water | 2008 |
New approach to measure protein binding based on a parallel artificial membrane assay and human serum albumin.
Topics: Humans; Kinetics; Membranes, Artificial; Permeability; Protein Binding; Serum Albumin | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Reductions in log P improved protein binding and clearance predictions enabling the prospective design of cannabinoid receptor (CB1) antagonists with desired pharmacokinetic properties.
Topics: Animals; Cytochrome P-450 Enzyme System; Drug Discovery; Half-Life; Protein Binding; Pyridazines; Rats; Receptor, Cannabinoid, CB1; Structure-Activity Relationship; Triazoles | 2013 |
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2014 |
Multifunctional scutellarin-rivastigmine hybrids with cholinergic, antioxidant, biometal chelating and neuroprotective properties for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Antioxidants; Apigenin; Blood-Brain Barrier; Butyrylcholinesterase; Carbamates; Cell Line; Chelating Agents; Cholinesterase Inhibitors; Cognition; Glucuronates; Humans; Mice; Molecular Docking Simulation; Neuroprotective Agents; Rats | 2015 |
Synthesis and evaluation of 4-hydroxyl aurone derivatives as multifunctional agents for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Benzofurans; Blood-Brain Barrier; Chelating Agents; Copper; Humans; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Peptide Fragments; Protein Aggregates; Swine | 2016 |
Multitarget drug design strategy against Alzheimer's disease: Homoisoflavonoid Mannich base derivatives serve as acetylcholinesterase and monoamine oxidase B dual inhibitors with multifunctional properties.
Topics: Acetylcholinesterase; Alzheimer Disease; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Humans; Isoflavones; Mannich Bases; Molecular Docking Simulation; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Structure-Activity Relationship | 2017 |
Aurone Mannich base derivatives as promising multifunctional agents with acetylcholinesterase inhibition, anti-β-amyloid aggragation and neuroprotective properties for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Cholinesterase Inhibitors; Drug Design; Electrophorus; Humans; Mannich Bases; Neuroprotective Agents; PC12 Cells; Rats | 2017 |
Design, synthesis and biological evaluation of 4'-aminochalcone-rivastigmine hybrids as multifunctional agents for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Blood-Brain Barrier; Chalcones; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Humans; Molecular Docking Simulation; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Rivastigmine; Structure-Activity Relationship; Swine | 2017 |
DL-3-n-butylphthalide-Edaravone hybrids as novel dual inhibitors of amyloid-β aggregation and monoamine oxidases with high antioxidant potency for Alzheimer's therapy.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Antipyrine; Benzofurans; Binding Sites; Blood-Brain Barrier; Edaravone; Humans; Hydrogen Bonding; Inhibitory Concentration 50; Molecular Docking Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Protein Binding; Protein Structure, Tertiary | 2017 |
Multifunctional thioxanthone derivatives with acetylcholinesterase, monoamine oxidases and β-amyloid aggregation inhibitory activities as potential agents against Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Cell Line; Cholinesterase Inhibitors; Humans; Kinetics; Models, Molecular; Monoamine Oxidase Inhibitors; Thioxanthenes; Xanthones | 2017 |
Design, synthesis and evaluation of novel ferulic acid-O-alkylamine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Coumaric Acids; Drug Design; Eels; Humans; Memory Disorders; Mice; PC12 Cells; Rats | 2017 |
Design, synthesis and biological evaluation of 3,4-dihydro-2(1H)-quinoline-O-alkylamine derivatives as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Drug Design; Electrophorus; Humans; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quinolines; Swine | 2017 |
Design, synthesis and biological evaluation of phthalimide-alkylamine derivatives as balanced multifunctional cholinesterase and monoamine oxidase-B inhibitors for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amines; Binding Sites; Blood-Brain Barrier; Cell Line, Tumor; Cell Survival; Cholinesterase Inhibitors; Cholinesterases; Drug Design; Humans; Inhibitory Concentration 50; Kinetics; Molecular Docking Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Phthalimides; Protein Structure, Tertiary; Structure-Activity Relationship | 2017 |
Design, synthesis and biological evaluation of 2-acetyl-5-O-(amino-alkyl)phenol derivatives as multifunctional agents for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Antioxidants; Benzophenones; Binding Sites; Blood-Brain Barrier; Cell Survival; Cholinesterase Inhibitors; Drug Design; Humans; Hydrogen Peroxide; Inhibitory Concentration 50; Molecular Docking Simulation; Monoamine Oxidase; Neuroprotective Agents; PC12 Cells; Permeability; Phenols; Piperazines; Protein Structure, Tertiary; Rats; Structure-Activity Relationship | 2017 |
Design, synthesis and evaluation of 4'-OH-flurbiprofen-chalcone hybrids as potential multifunctional agents for Alzheimer's disease treatment.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Blood-Brain Barrier; Cell Line; Cell Survival; Chalcones; Chelating Agents; Copper; Drug Design; Flurbiprofen; Humans; Lipopolysaccharides; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nitric Oxide; Peptide Fragments; Recombinant Proteins; Structure-Activity Relationship | 2018 |
Multifunctional 5,6-dimethoxybenzo[d]isothiazol-3(2H)-one-N-alkylbenzylamine derivatives with acetylcholinesterase, monoamine oxidases and β-amyloid aggregation inhibitory activities as potential agents against Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Benzylamines; Blood-Brain Barrier; Cholinesterase Inhibitors; Drug Design; Humans; Kinetics; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Permeability; Protein Aggregates; Recombinant Proteins; Structure-Activity Relationship; Thiazoles | 2018 |
Development of Piperazinediones as dual inhibitor for treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Butyrylcholinesterase; Diketopiperazines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Matrix Metalloproteinase 2; Molecular Structure; Neuroprotective Agents; Structure-Activity Relationship | 2018 |
Discovery of novel anti-tuberculosis agents with pyrrolo[1,2-a]quinoxaline-based scaffold.
Topics: Antineoplastic Agents; Antitubercular Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Pyrroles; Quinoxalines; Structure-Activity Relationship | 2018 |
Discovery of novel 2,5-dihydroxyterephthalamide derivatives as multifunctional agents for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Butyrylcholinesterase; Chelating Agents; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Discovery; Humans; Models, Molecular; Molecular Structure; Peptide Fragments; Phthalimides; Protein Aggregates; Structure-Activity Relationship | 2018 |
Design and development of some phenyl benzoxazole derivatives as a potent acetylcholinesterase inhibitor with antioxidant property to enhance learning and memory.
Topics: Antioxidants; Benzoxazoles; Cholinesterase Inhibitors; Drug Design; Humans; Learning; Memory; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2019 |
Discovery of 4'-OH-flurbiprofen Mannich base derivatives as potential Alzheimer's disease treatment with multiple inhibitory activities.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Blood-Brain Barrier; Cell Line; Cholinesterase Inhibitors; Drug Design; Drug Discovery; Electrophorus; Flurbiprofen; Humans; Mannich Bases; Molecular Docking Simulation; Peptide Fragments; Protein Aggregates; Rats; Swine | 2019 |
Design, synthesis, in-silico and biological evaluation of novel chalcone-O-carbamate derivatives as multifunctional agents for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Butyrylcholinesterase; Chalcones; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Eels; Female; Horses; Humans; Male; Maze Learning; Mice; Mice, Inbred Strains; Models, Molecular; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Peptide Fragments; Protein Aggregates; Rats; Structure-Activity Relationship | 2019 |
Design, synthesis, in-silico and biological evaluation of novel chalcone derivatives as multi-function agents for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Butyrylcholinesterase; Chalcone; Cholinesterase Inhibitors; Drug Design; Eels; Horses; Humans; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Peptide Fragments; Protein Aggregates | 2019 |
The development of 2-acetylphenol-donepezil hybrids as multifunctional agents for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Cholinesterases; Donepezil; Drug Design; Drug Development; Humans; Kinetics; Models, Molecular; Molecular Docking Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Structure-Activity Relationship | 2019 |
Development of chalcone-O-alkylamine derivatives as multifunctional agents against Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Biological Transport; Blood-Brain Barrier; Butyrylcholinesterase; Chalcones; Chelating Agents; Cholinesterase Inhibitors; Coordination Complexes; Copper; Drug Design; Female; Humans; Male; Memory Disorders; Mice; Molecular Docking Simulation; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Protein Binding; Scopolamine; Structure-Activity Relationship | 2019 |
Human Serum Albumin Binding in a Vial: A Novel UV-pH Titration Method To Assist Drug Design.
Topics: Binding Sites; Chemistry, Pharmaceutical; Drug Design; Humans; Hydrogen-Ion Concentration; Molecular Docking Simulation; Pharmaceutical Preparations; Protein Binding; Serum Albumin, Human; Spectrophotometry, Ultraviolet; Titrimetry | 2020 |
Synthesis and evaluation of dual fatty acid amide hydrolase-monoacylglycerol lipase inhibition and antinociceptive activities of 4-methylsulfonylaniline-derived semicarbazones.
Topics: Amidohydrolases; Analgesics; Enzyme Inhibitors; Humans; Molecular Docking Simulation; Monoacylglycerol Lipases; Neuralgia; Semicarbazones | 2022 |
Effects of benzodiazepines on the binding of tryptophan in serum. Consequences on 5-hydroxyindoles concentrations in the rat brain.
Topics: Amino Acids; Animals; Anti-Anxiety Agents; Brain Chemistry; Chlordiazepoxide; Diazepam; Hydroxyindoleacetic Acid; In Vitro Techniques; Indoles; Male; Oxazepam; Protein Binding; Rats; Serum Albumin; Time Factors; Tryptophan; Tyrosine | 1975 |
Interactions between narcotic analgesics and benzodiazepine derivatives on behavior in the mouse.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Benzodiazepines; Brain; Brain Chemistry; Dextroamphetamine; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Male; Methadone; Methods; Mice; Morphine; Motor Activity; Naloxone; Oxazepam; Reaction Time | 1976 |
[Analysis of the structure of the components of the convulsive action of corazole following administration of sulazepam and its metabolites to mice].
Topics: Animals; Anti-Anxiety Agents; Diazepam; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred CBA; Nordazepam; Oxazepam; Pentylenetetrazole; Seizures; Time Factors | 1976 |
Feto-maternal concentrations of diazepam and W-demethyldiazepam after intra-amniotic diazepam injection.
Topics: Adolescent; Adult; Amniotic Fluid; Brain Chemistry; Diazepam; Female; Fetal Blood; Humans; Injections; Injections, Intramuscular; Kinetics; Liver; Maternal-Fetal Exchange; Nordazepam; Oxazepam; Pregnancy | 1976 |
[Therapeutic notes: benzodiazepines].
Topics: Anti-Anxiety Agents; Chemical Phenomena; Chemistry; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Flurazepam; Humans; Lorazepam; Nitrazepam; Oxazepam | 1976 |
Disposition of three benzodiazepines after single oral administration in man.
Topics: Administration, Oral; Anti-Anxiety Agents; Clorazepate Dipotassium; Diazepam; Drug Evaluation; Female; Half-Life; Humans; Male; Oxazepam | 1977 |
Kinetics and mechanisms of hydrolysis of 1,4-benzodiazepines II: oxazepam and diazepam.
Topics: Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Diazepam; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Oxazepam; Spectrophotometry; Thermodynamics | 1977 |
IARC monographs on the evaluation of the carcinogenic risk of chemicals to man: some miscellaneous pharmaceutical substances.
Topics: Acriflavine; Animals; Anthralin; Aurothioglucose; Carcinogens; Chloroquine; Diazepam; Ethanolamines; Ethionamide; Female; Humans; Hycanthone; Male; Metronidazole; Neoplasms; Neoplasms, Experimental; Oxazepam; Oxymetholone; Oxyphenbutazone; Oxyquinoline; Phenacetin; Phenobarbital; Phenylbutazone; Phenytoin; Pregnancy; Pyrimethamine; Risk | 1977 |
Clinical implications of benzodiazepine pharmacokinetics.
Topics: Administration, Oral; Adult; Age Factors; Aged; Alcoholism; Anti-Anxiety Agents; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Drug Interactions; Humans; Injections, Intramuscular; Injections, Intravenous; Intestinal Absorption; Liver; Lorazepam; Medazepam; Oxazepam | 1977 |
[Modulation of autonomic correlates of emotional stress and adaptive responses].
Topics: Adaptation, Physiological; Animals; Anti-Anxiety Agents; Autonomic Nervous System; Blood Pressure; Cats; Chlordiazepoxide; Diazepam; Dogs; Dose-Response Relationship, Drug; Heart Rate; Humans; Male; Muscle Contraction; Muscles; Nitrazepam; Oxazepam; Reflex; Stress, Psychological | 1978 |
[Psychophysiologic characteristics of the individual psychotropic activity of benzodiazepine derivatives under experimental conditions].
Topics: Animals; Anti-Anxiety Agents; Anxiety; Cats; Chlordiazepoxide; Diazepam; Humans; Lorazepam; Neurotic Disorders; Nitrazepam; Oxazepam; Stress, Psychological | 1978 |
High-dose benzodiazepines in the treatment of severe neurotic anxiety.
Topics: Adult; Aged; Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Female; Flurazepam; Humans; Male; Oxazepam; Substance-Related Disorders | 1978 |
Pharmacokinetic understanding of antianxiety drug therapy.
Topics: Adult; Anti-Anxiety Agents; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Dose-Response Relationship, Drug; Humans; Nordazepam; Oxazepam; Prazepam | 1978 |
Disposition and elimination of minor tranquilizers in the aged and in patients with liver disease.
Topics: Aged; Aging; Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Hepatitis; Humans; Liver Cirrhosis; Liver Diseases; Lorazepam; Oxazepam | 1978 |
Interaction of disulfiram with benzodiazepines.
Topics: Adult; Alcoholism; Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Disulfiram; Drug Interactions; Humans; Kinetics; Male; Oxazepam | 1978 |
Effects of liver disease and of aging on the disposition and elimination of sedatives.
Topics: Aging; Anti-Anxiety Agents; Chlordiazepoxide; Chlorpromazine; Diazepam; Half-Life; Hepatitis, Viral, Human; Humans; Liver Cirrhosis; Liver Diseases; Lorazepam; Meprobamate; Oxazepam | 1978 |
Effects of antianxiety agents on relaxation training: a preliminary investigation.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety; Diazepam; Female; Flurazepam; Humans; Male; Mental Disorders; Middle Aged; Neurotic Disorders; Oxazepam; Personality Disorders; Phenobarbital; Relaxation Therapy; Stress, Psychological | 1978 |
The effects of liver disease and aging on the disposition of diazepam, chlordiazepoxide, oxazepam and lorazepam in man.
Topics: Administration, Oral; Adult; Aged; Aging; Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Female; Half-Life; Hepatitis, Viral, Human; Humans; Injections, Intravenous; Liver Cirrhosis, Alcoholic; Liver Diseases; Lorazepam; Male; Middle Aged; Oxazepam | 1978 |
A radioreceptor assay for benzodiazepines.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Brain; Diazepam; Humans; Male; Membranes; Methods; Nitrazepam; Oxazepam; Radioligand Assay; Rats | 1979 |
Simultaneous determination of diazepam and its metabolies N-desmethyldiazepam, oxydiazepam and oxazepam in plasma and urine of man and dog by means of high-performance liquid chromatography.
Topics: Animals; Anti-Anxiety Agents; Chromatography, High Pressure Liquid; Diazepam; Dogs; Humans; Nordazepam; Oxazepam; Species Specificity; Temazepam | 1979 |
Benzodiazepines: some aspects of their clinical pharmacology.
Topics: Anti-Anxiety Agents; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Humans; Lorazepam; Oxazepam; Prazepam | 1979 |
Proceedings: Investigations into the suitability of oxazepam and diazepam as antidotes against gamma-hexachlorocyclohexane (lindane).
Topics: Animals; Antidotes; Diazepam; Hexachlorocyclohexane; Lethal Dose 50; Mice; Oxazepam | 1975 |
Floppy-infant syndrome: Is oxazepam the answer?
Topics: Diazepam; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Maternal-Fetal Exchange; Muscle Hypotonia; Oxazepam; Pre-Eclampsia; Pregnancy | 1977 |
[The influence of oxazepam and diazepam on the sexual behaviour and level of GABA biogenic amines in a male rat's brain (author's transl)].
Topics: Animals; Brain; Diazepam; Drug Synergism; Fenclonine; gamma-Aminobutyric Acid; Male; Oxazepam; Rats; Sexual Behavior, Animal | 1979 |
Diazepam and its hydroxylated metabolites: studies on sleep in healthy man.
Topics: Adult; Aging; Diazepam; Humans; Hydroxylation; Male; Middle Aged; Oxazepam; Sleep; Sleep, REM; Temazepam | 1979 |
Toxicological and pharmacological investigations of pinazepam (7-chloro-1-propargyl-5-phenyl-3H-1,4-benzodiazepin-2-one): a new psychotherapeutic agent.
Topics: Abnormalities, Drug-Induced; Aggression; Analgesia; Animals; Anti-Anxiety Agents; Blood Pressure; Cats; Diazepam; Dogs; Exploratory Behavior; Female; Heart Rate; Humans; Male; Mice; Motor Activity; Motor Skills; Muscle Tonus; Oxazepam; Pregnancy; Rabbits; Rats; Reflex; Seizures; Sleep | 1975 |
Multiple oral doses of diazepam, oxazepam and phenobarbital to dogs--behavioural effects and correlation with antipyrine half-life.
Topics: Administration, Oral; Animals; Antipyrine; Behavior, Animal; Diazepam; Dogs; Drug Evaluation, Preclinical; Half-Life; Male; Oxazepam; Phenobarbital; Time Factors | 1977 |
High-pressure liquid chromatographic analysis of diazepam, oxazepam and N-desmethyldiazepam in human blood.
Topics: Chromatography, High Pressure Liquid; Diazepam; Humans; Nordazepam; Oxazepam | 1978 |
Plasma and urine concentrations of diazepam and its metabolites in children, adults and in diazepam-intoxicated patients.
Topics: Adult; Aging; Biotransformation; Child; Creatinine; Diazepam; Female; Humans; Infant; Infant, Newborn; Kinetics; Male; Nordazepam; Oxazepam | 1978 |
Rapid recovery from massive diazepam overdose.
Topics: Adult; Biotransformation; Diazepam; Female; Half-Life; Humans; Male; Middle Aged; Nordazepam; Oxazepam; Remission, Spontaneous; Suicide, Attempted; Temazepam; Time Factors | 1978 |
Fluorescence--TLC densitometric determination of diazepam and other 1,4-benzodiazepines in serum.
Topics: Benzodiazepines; Chromatography, Thin Layer; Densitometry; Diazepam; Humans; Methods; Nordazepam; Oxazepam; Spectrometry, Fluorescence | 1978 |
Liquid-chromatographic assay of diazepam and its major metabolites in plasma.
Topics: Chromatography, High Pressure Liquid; Diazepam; Humans; Nordazepam; Oxazepam | 1979 |
Effect of age on the pharmacokinetics of diazepam given in conjunction with spinal anesthesia.
Topics: Adult; Age Factors; Aged; Anesthesia, Spinal; Body Water; Diazepam; Humans; Kinetics; Middle Aged; Nordazepam; Oxazepam; Temazepam | 1979 |
[A screening radioimmunoassay for 1,4-benzodiazepines in human blood, serum, and urine using anti-oxazepam-hemisuccinate-antibodies (author's transl)].
Topics: Benzodiazepines; Chromatography, Gas; Chromatography, Thin Layer; Diazepam; Humans; Nordazepam; Oxazepam; Radioimmunoassay; Succinates | 1979 |
Intravascular factors affecting diazepam binding to human serum albumin.
Topics: Binding, Competitive; Dialysis; Diazepam; Fatty Acids; Humans; Nordazepam; Oleic Acids; Oxazepam; Palmitic Acids; Protein Binding; Serum Albumin | 1979 |
Massive benzodiazepine requirements during acute alcohol withdrawal.
Topics: Adult; Alcohol Withdrawal Delirium; Alcoholism; Diazepam; Dose-Response Relationship, Drug; Half-Life; Humans; Male; Oxazepam; Substance Withdrawal Syndrome | 1979 |
Performance studies with diazepam and its hydroxylated metabolites.
Topics: Barbiturates; Diazepam; Flurazepam; Humans; Hydroxylation; Motor Skills; Oxazepam; Temazepam; Time Factors | 1979 |
Choice of a benzodiazepine for treatment of anxiety or insomnia.
Topics: Anxiety; Benzodiazepines; Chlordiazepoxide; Diazepam; Humans; Oxazepam; Sleep Initiation and Maintenance Disorders | 1977 |
On the acute effect of some drugs on higher nervous activity in man followed up by the laboratory language method [proceedings].
Topics: Adolescent; Adult; Diazepam; Double-Blind Method; Female; Higher Nervous Activity; Humans; Male; Methods; Oxazepam; Verbal Learning; Word Association Tests | 1977 |
Use of internal standards in the estimation of diazepam in plasma.
Topics: Chromatography, Gas; Diazepam; Humans; Methods; Oxazepam; Prazepam | 1978 |
Stereospecific benzodiazepine receptor binding by the enantiomers of oxazepam sodium hemisuccinate.
Topics: Animals; Binding, Competitive; Brain; Diazepam; In Vitro Techniques; Oxazepam; Rats; Receptors, Drug; Stereoisomerism; Synaptosomes | 1978 |
Thin-layer detection of diazepam and/or chilordiazepoxide alone or in combination with major drugs of abuse in drug abuse urine screening programs.
Topics: Chlordiazepoxide; Chromatography, Thin Layer; Clorazepate Dipotassium; Diazepam; Humans; Indicators and Reagents; Mass Screening; Oxazepam; Substance-Related Disorders | 1978 |
Regional distribution of diazepam and its metabolites in the brain of cat after chronic treatment.
Topics: Animals; Brain; Cats; Cerebral Cortex; Diazepam; Oxazepam | 1976 |
Acute effects of oxazepam, diazepam and methylperone, alone and in combination with alcohol on sedation, coordination and mood.
Topics: Adult; Attention; Butyrophenones; Diazepam; Drug Interactions; Emotions; Ethanol; Flicker Fusion; Humans; Male; Middle Aged; Motor Skills; Oxazepam; Piperidines; Tranquilizing Agents | 1976 |
Blockade of the specific lethal effects of narcotic analgesics in the mouse.
Topics: Animals; Benzodiazepines; Diazepam; Dose-Response Relationship, Drug; Lethal Dose 50; Male; Methadone; Mice; Morphine; Nalorphine; Naloxone; Narcotic Antagonists; Oxazepam; Trimethadione | 1976 |
Determination of pinazepam and its metabolites in serum, urine and brain by gas-liquid chromatography and mass spectrometry.
Topics: Administration, Oral; Animals; Benzodiazepines; Benzodiazepinones; Brain; Chromatography, Gas; Diazepam; Dogs; Humans; Mass Spectrometry; Oxazepam; Rats | 1975 |
"Paradoxical rage reactions" during psychotropic medication.
Topics: Adult; Aggression; Anger; Child; Clorazepate Dipotassium; Diazepam; Ethanol; Female; Humans; Individuality; Male; Oxazepam; Psychotropic Drugs; Rage | 1975 |
Cerebrospinal-fluid concentration of diazepam and its metabolites in man.
Topics: Adult; Aged; Blood Proteins; Diazepam; Female; Humans; Male; Middle Aged; Oxazepam | 1975 |
[Leukopenia following benzodiazepine derivatives].
Topics: Adult; Benzodiazepines; Diazepam; Humans; Leukopenia; Male; Oxazepam; Penicillins | 1975 |
Stimulatory effects of chlordiazepoxide, diazepam and oxazepam on the drug-metabolizing enzymes in microsomes.
Topics: Aniline Compounds; Animals; Benzene; Body Temperature; Chlordiazepoxide; Diazepam; Drug Tolerance; Hydroxylation; Kinetics; Male; Microsomes, Liver; Mixed Function Oxygenases; Muscle Contraction; Organ Size; Oxazepam; Oxidoreductases; Proteins; Rats; Stimulation, Chemical | 1975 |
Fluorometric screening method for detecting benzodiazepines in blood and urine.
Topics: Benzodiazepines; Chlordiazepoxide; Diazepam; Gastric Juice; Humans; Oxazepam; Spectrometry, Fluorescence | 1975 |
Plasma concentrations of diazepam and its metabolites after peroral, intramuscular, and rectal administration. Correlation between plasma concentration and sedatory effect of diazepam.
Topics: Administration, Oral; Adult; Central Nervous System; Diazepam; Female; Humans; Injections, Intramuscular; Intestinal Absorption; Male; Oxazepam; Pharmaceutical Vehicles; Rectum; Suppositories | 1975 |
The protein binding of diazepam and N-demethyldiazepam in patients with poor renal function.
Topics: Adolescent; Adult; Aged; Creatinine; Diazepam; Female; Humans; Kidney Diseases; Male; Middle Aged; Oxazepam; Protein Binding; Time Factors | 1976 |
Biliary elimination of diazepam in man.
Topics: Adult; Aged; Bile; Diazepam; Female; Half-Life; Humans; Kinetics; Male; Middle Aged; Oxazepam; Time Factors | 1976 |
Detoxification for triazolam physical dependence.
Topics: Adult; Alcoholism; Diazepam; Dose-Response Relationship, Drug; Female; Half-Life; Hospitalization; Humans; Male; Middle Aged; Oxazepam; Substance Abuse Treatment Centers; Substance Withdrawal Syndrome; Substance-Related Disorders; Triazolam | 1992 |
Neurodevelopment in late infancy after prenatal exposure to benzodiazepines--a prospective study.
Topics: Abnormalities, Drug-Induced; Anti-Anxiety Agents; Arousal; Body Height; Body Weight; Cephalometry; Diazepam; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Infant; Longitudinal Studies; Lorazepam; Male; Motor Activity; Neurologic Examination; Oxazepam; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Psychomotor Performance; Risk Factors | 1992 |
Comparative study of interaction mode of diazepines with human serum albumin and alpha 1-acid glycoprotein.
Topics: Anti-Anxiety Agents; Bromazepam; Clonazepam; Diazepam; Flunitrazepam; Humans; Orosomucoid; Oxazepam; Protein Binding; Regression Analysis; Serum Albumin; Spectrometry, Fluorescence | 1992 |
Withdrawal precipitation by benzodiazepine receptor antagonists in dogs chronically treated with diazepam or the novel anxiolytic and anticonvulsant beta-carboline abecarnil.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Carbolines; Diazepam; Dogs; Female; Flumazenil; GABA-A Receptor Antagonists; Oxazepam; Substance Withdrawal Syndrome | 1992 |
Quantitation by gas chromatography with selected-ion monitoring mass spectrometry of "natural" diazepam, N-desmethyldiazepam and oxazepam in normal human serum.
Topics: Adult; Analysis of Variance; Diazepam; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Nordazepam; Oxazepam | 1992 |
Benzodiazepine requirements during alcohol withdrawal syndrome: clinical implications of using a standardized withdrawal scale.
Topics: Administration, Oral; Adult; Alcohol Withdrawal Delirium; Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Hospitalization; Humans; Length of Stay; Lorazepam; Neurologic Examination; Oxazepam; Retrospective Studies; Temazepam; Triazolam | 1991 |
A graph-theoretic approach to modeling metabolic pathways.
Topics: Anti-Anxiety Agents; Computers; Diazepam; Humans; Medazepam; Models, Biological; Models, Statistical; Oxazepam | 1991 |
Distribution of diazepam, nordiazepam, and oxazepam between brain extraneuronal space, brain tissue, plasma, and cerebrospinal fluid in diazepam and nordiazepam dependent dogs.
Topics: Animals; Brain; Diazepam; Dogs; Extracellular Space; Female; Nordazepam; Oxazepam; Substance-Related Disorders | 1991 |
Determination of diazepam and nordazepam in milk and plasma in the presence of oxazepam and temazepam.
Topics: Chromatography, High Pressure Liquid; Diazepam; Flurazepam; Humans; Hydrogen-Ion Concentration; Milk, Human; Nordazepam; Oxazepam; Temazepam | 1991 |
[Premedication and analgesic dose procedures in dental medicine].
Topics: Anesthesia, Dental; Anesthesia, Local; Buprenorphine; Clorazepate Dipotassium; Diazepam; Flunitrazepam; Humans; Lorazepam; Meperidine; Midazolam; Morphine; Oxazepam; Pain; Pentazocine; Pirinitramide; Preanesthetic Medication | 1991 |
Benzodiazepine concentrations in brain directly reflect receptor occupancy: studies of diazepam, lorazepam, and oxazepam.
Topics: Animals; Anti-Anxiety Agents; Brain; Chromatography, Gas; Diazepam; Half-Life; Hydroxylation; Injections, Intravenous; Lorazepam; Male; Mice; Oxazepam; Receptors, GABA-A | 1990 |
Characterization by saturation studies of the in vivo binding of [3H]flunitrazepam in mouse brain.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Clonazepam; Diazepam; Flunitrazepam; Kinetics; Mice; Nordazepam; Oxazepam | 1991 |
Excretion of diazepam and its metabolites in human milk during withdrawal from combination high dose diazepam and oxazepam.
Topics: Adult; Diazepam; Drug Combinations; Female; Humans; Infant; Milk, Human; Nordazepam; Oxazepam; Substance Withdrawal Syndrome; Substance-Related Disorders; Temazepam | 1990 |
Glucuronidation of codeine and morphine in human liver and kidney microsomes: effect of inhibitors.
Topics: Adult; Amitriptyline; Chloramphenicol; Codeine; Diazepam; Glucuronates; Glucuronosyltransferase; Humans; In Vitro Techniques; Kidney; Kinetics; Microsomes; Microsomes, Liver; Morphine; Oxazepam; Probenecid | 1990 |
[Tranquilizer poisonings].
Topics: Chlordiazepoxide; Diagnosis; Diazepam; Humans; Oxazepam; Tranquilizing Agents | 1990 |
[Laboratory diagnosis of acute poisoning of children by elenium, seduxen and tazepam].
Topics: Acute Disease; Child; Child, Preschool; Chlordiazepoxide; Diazepam; Humans; Methods; Oxazepam | 1988 |
In vitro drug metabolism and pharmacokinetics of diazepam in cynomolgus monkey hepatocytes during culture for six days.
Topics: Animals; Cells, Cultured; Cytochrome P-450 Enzyme System; Diazepam; Liver; Macaca fascicularis; Male; Models, Biological; Nordazepam; Oxazepam; Oxygenases; Temazepam; Time Factors | 1989 |
Potentiation of ifosfamide toxicity by chlordiazepoxide, diazepam and oxazepam.
Topics: Animals; Chlordiazepoxide; Diazepam; Drug Synergism; Ifosfamide; Male; Mice; Oxazepam; Oxidoreductases | 1989 |
Drugs in dentistry. Agents for anxiety disorders.
Topics: Alprazolam; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Chlordiazepoxide; Clorazepate Dipotassium; Dental Care; Diazepam; Humans; Oxazepam | 1985 |
GABA-B receptor activation and conflict behaviour.
Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Baclofen; Behavior, Animal; Bicuculline; Cell Membrane; Cerebellum; Cerebral Cortex; Conflict, Psychological; Diazepam; Male; Oxazepam; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1988 |
Drug interactions between imipramine and benzodiazepines in rats.
Topics: Animals; Anti-Anxiety Agents; Blood Proteins; Brain; Chromatography, High Pressure Liquid; Desipramine; Diazepam; Drug Interactions; Hypothermia; Imipramine; Liver; Male; Oxazepam; Protein Binding; Rats; Rats, Inbred Strains; Stress, Physiological | 1988 |
[Action of benzodiazepines on the immune response].
Topics: Animals; Anti-Anxiety Agents; Diazepam; Immunity, Cellular; Mice; Mice, Inbred CBA; Oxazepam; Rosette Formation | 1988 |
Kinetics of drug action in disease states. XXIV. Pharmacodynamics of diazepam and its active metabolites in rats.
Topics: Animals; Anti-Anxiety Agents; Brain; Diazepam; Female; Nordazepam; Oxazepam; Rats; Rats, Inbred Lew; Reflex; Temazepam | 1988 |
Potencies of diazepam metabolites in rats trained to discriminate diazepam.
Topics: Animals; Conditioning, Operant; Diazepam; Discrimination, Psychological; Dose-Response Relationship, Drug; Male; Nordazepam; Oxazepam; Rats; Rats, Inbred Strains; Temazepam | 1986 |
Validation of a radioreceptor assay technique for monitoring pharmacological active material during intensive diazepam tetanus therapy.
Topics: Biotransformation; Chromatography, Gas; Cimetidine; Diazepam; Humans; Kinetics; Middle Aged; Nordazepam; Oxazepam; Radioligand Assay; Tetanus | 1987 |
Placental and blood-CSF transfer of orally administered diazepam in the same person.
Topics: Adult; Biotransformation; Diazepam; Female; Fetal Blood; Humans; Maternal-Fetal Exchange; Nordazepam; Oxazepam; Pregnancy | 1987 |
Analysis of chlorodesmethyldiazepam and its metabolites in plasma and urine.
Topics: Anti-Anxiety Agents; Benzodiazepines; Chromatography, Gas; Diazepam; Glucuronates; Humans; Lorazepam; Nordazepam; Oxazepam | 1987 |
Simultaneous determination of diazepam and its active metabolites in rat serum, brain and cerebrospinal fluid by high-performance liquid chromatography.
Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Diazepam; Female; Nordazepam; Oxazepam; Postural Balance; Rats; Rats, Inbred Strains; Temazepam | 1987 |
Imipramine treatment alters the pharmacokinetics and pharmacodynamics of diazepam.
Topics: Animals; Blood Proteins; Brain Chemistry; Diazepam; Drug Interactions; Imipramine; Liver; Male; Nordazepam; Oxazepam; Pentylenetetrazole; Protein Binding; Rats; Rats, Inbred Strains; Temazepam | 1987 |
Precipitation of abstinence in nordiazepam- and diazepam-dependent dogs.
Topics: Analysis of Variance; Animals; Diazepam; Dogs; Flumazenil; Nordazepam; Oxazepam; Pyrazoles; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders | 1988 |
Escalation of feline predation along a gradient from avoidance through "play" to killing.
Topics: Aggression; Agonistic Behavior; Animals; Appetitive Behavior; Brain Mapping; Cats; Diazepam; Female; Hypothalamic Area, Lateral; Male; Oxazepam; Predatory Behavior; Reaction Time | 1988 |
Pharmacokinetics and distribution of diazepam and oxazepam in early pregnancy.
Topics: Adolescent; Adult; Diazepam; Female; Humans; Oxazepam; Pregnancy; Pregnancy Trimester, First | 1988 |
Determination of diazepam and oxazepam using high-performance liquid chromatography and fourth-derivative spectrophotometric techniques.
Topics: Chromatography, High Pressure Liquid; Diazepam; Oxazepam; Spectrophotometry; Tablets | 1988 |
Acute confusional state with status petit mal as a withdrawal syndrome--and five year follow-up.
Topics: Acute Disease; Cognition Disorders; Confusion; Diazepam; Follow-Up Studies; Humans; Injections, Intravenous; Male; Middle Aged; Oxazepam; Status Epilepticus; Substance Withdrawal Syndrome; Time Factors | 1988 |
[Drug interaction between imipramine hydrochloride and benzodiazepines when administered orally for 15 days].
Topics: Administration, Oral; Animals; Benzodiazepines; Diazepam; Drug Interactions; Imipramine; Injections, Intravenous; Male; Oxazepam; Rats; Rats, Inbred Strains | 1988 |
Relative abuse of diazepam and oxazepam: prescription forgeries and theft/loss reports in Sweden.
Topics: Cross-Sectional Studies; Depressive Disorder; Diazepam; Drug and Narcotic Control; Drug Prescriptions; Humans; Neurotic Disorders; Oxazepam; Sleep Initiation and Maintenance Disorders; Substance-Related Disorders; Sweden; Theft | 1986 |
Tumor-promoting activity of benzodiazepine tranquilizers, diazepam and oxazepam, in mouse liver.
Topics: Aminopyrine N-Demethylase; Animals; Body Weight; Cocarcinogenesis; Cytochrome P-450 Enzyme System; Diazepam; Diethylnitrosamine; Enzyme Induction; Liver; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred Strains; Organ Size; Oxazepam; Phenobarbital; Time Factors | 1986 |
Long-lasting anticonvulsant effects of diazepam in different mouse strains: correlations with brain concentrations and receptor occupancy.
Topics: Animals; Anticonvulsants; Brain Chemistry; Diazepam; Mice; Mice, Inbred C3H; Nordazepam; Oxazepam; Pentylenetetrazole; Seizures; Species Specificity; Time Factors | 1985 |
Liquid-chromatographic assay of diazepam and its major metabolites in serum, and application to pharmacokinetic study of high doses of diazepam in schizophrenics.
Topics: Administration, Oral; Chromatography, High Pressure Liquid; Diazepam; Female; Humans; Kinetics; Nordazepam; Oxazepam; Schizophrenia; Temazepam | 1985 |
Severe withdrawal syndrome after substitution of a short-acting benzodiazepine for a long-acting benzodiazepine.
Topics: Diazepam; Female; Half-Life; Humans; Middle Aged; Nordazepam; Oxazepam; Substance Withdrawal Syndrome | 1985 |
N-desmethyldiazepam physical dependence in dogs.
Topics: Analysis of Variance; Animals; Body Weight; Diazepam; Dogs; Drinking; Energy Intake; Female; Lorazepam; Muscle Spasticity; Nordazepam; Oxazepam; Paresthesia; Substance Withdrawal Syndrome; Temazepam; Time Factors | 1985 |
Stereoselective binding of 3-acetoxy-, and 3-hydroxy-1,4-benzodiazepine-2-ones to human serum albumin. Selective allosteric interaction with warfarin enantiomers.
Topics: Benzodiazepines; Diazepam; Humans; Lorazepam; Oxazepam; Research Design; Serum Albumin; Stereoisomerism; Structure-Activity Relationship; Ultrafiltration; Warfarin | 1986 |
Anticonvulsive and muscle-relaxant activity of some benzodiazepines in spontaneously hypertensive rats (SHR).
Topics: Animals; Anticonvulsants; Benzodiazepines; Chlordiazepoxide; Diazepam; Drug Evaluation, Preclinical; Female; Male; Muscle Relaxants, Central; Oxazepam; Rats; Rats, Inbred SHR | 1985 |
An examination of acid-base equilibria of 1,4-benzodiazepines by spectrophotometry.
Topics: Benzazepines; Chemical Phenomena; Chemistry; Chlordiazepoxide; Diazepam; Hydrogen-Ion Concentration; Nitrazepam; Oxazepam; Spectrophotometry, Ultraviolet | 1973 |
[COMPLARATIVE CHARACTERISTICS OF THE CLINICAL EFFECTS OF TRANQUILIZERS].
Topics: Anthracenes; Anti-Anxiety Agents; Benzoates; Benzodiazepinones; Chlordiazepoxide; Chlorobenzenes; Diazepam; Epilepsy; Humans; Mathematics; Meprobamate; Morpholines; Neurotic Disorders; Nitrazepam; Oxazepam; Psychopharmacology; Psychotic Disorders; Tranquilizing Agents | 1974 |
Gas chromatographic analysis of medazepam and its metabolites using an electrolytic conductivity detector.
Topics: Animals; Anti-Anxiety Agents; Azepines; Chromatography, Gas; Diazepam; Electric Conductivity; Electrochemistry; Hydrogen-Ion Concentration; Oxazepam; Rats; Temperature | 1974 |
Action of drugs on the electrical activity of the red nucleus.
Topics: Animals; Barbiturates; Cerebral Cortex; Chlordiazepoxide; Diazepam; Electrodes; Electrophysiology; Ethanol; Hexobarbital; Hippocampus; Male; Mephenesin; Meprobamate; Oxazepam; Pentobarbital; Phenobarbital; Rabbits; Red Nucleus; Thiopental; Urethane | 1969 |
[Therapy of spastic syndromes].
Topics: Carisoprodol; Chlordiazepoxide; Chlormezanone; Chlorzoxazone; Curare; Diazepam; Guaifenesin; Humans; Mephenesin; Meprobamate; Muscle Cramp; Muscle Relaxants, Central; Muscle Spasticity; Muscle Tonus; Muscles; Nervous System Diseases; Neuromuscular Diseases; Neuromuscular Nondepolarizing Agents; Orphenadrine; Oxazepam; Phenols; Procaine; Spasm; Tranquilizing Agents | 1969 |
Influence of pH on the benzodiazepine-human serum albumin complex. Circular dichroism studies.
Topics: Benzazepines; Benzodiazepinones; Binding Sites; Chemical Phenomena; Chemistry; Chlordiazepoxide; Circular Dichroism; Diazepam; Flurazepam; Humans; Hydrogen-Ion Concentration; Kinetics; Nitrazepam; Osmolar Concentration; Oxazepam; Protein Binding; Serum Albumin | 1974 |
The chromatographic separation of mixtures of benzodiazepine drugs.
Topics: Aluminum Silicates; Benzazepines; Chlordiazepoxide; Chromatography, Paper; Chromatography, Thin Layer; Diazepam; Methods; Oxazepam; Silicon Dioxide; Ultraviolet Rays | 1971 |
[Neurological analysis of the action of tranquilizing agents--benzodiazepine derivatives].
Topics: Antisocial Personality Disorder; Benzazepines; Chlordiazepoxide; Diazepam; Humans; Hypertension; Meniere Disease; Mental Disorders; Migraine Disorders; Neurotic Disorders; Nitrazepam; Oxazepam; Peripheral Nervous System Diseases; Schizophrenia; Tranquilizing Agents | 1972 |
Regional cyclic nucleotide phosphodiesterase activity in cat central nervous system: effects of benzodiazepines.
Topics: Animals; Benzazepines; Brain; Cats; Caudate Nucleus; Cell Line; Cerebellum; Cerebral Cortex; Chlordiazepoxide; Cyclic AMP; Cyclic GMP; Diazepam; Hippocampus; Hypothalamus; Medulla Oblongata; Mesencephalon; Mice; Neuroblastoma; Olfactory Bulb; Oxazepam; Phosphodiesterase Inhibitors; Pituitary Gland; Pons; Rats; Spinal Cord; Thalamus | 1974 |
Adenosine 3',5'-monophosphate in guinea pig cerebral cortical slices: effect of benzodiazepines.
Topics: Adenosine; Animals; Cerebral Cortex; Chlordiazepoxide; Cyclic AMP; Diazepam; Histamine; Kinetics; Male; Norepinephrine; Oxazepam; Time Factors; Tranquilizing Agents | 1974 |
Proceedings: Adenosine 3',5'-monophosphate in cerebral cortical slices from guinea pig and rat: effect of benzodiazepines.
Topics: Adenosine; Animals; Benzodiazepinones; Cerebral Cortex; Chlordiazepoxide; Cyclic AMP; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Histamine; In Vitro Techniques; Norepinephrine; Oxazepam; Rats | 1974 |
Inhibition of phosphodiesterase activity in brain cortical slices from guinea pig and rat.
Topics: Adenosine; Animals; Benzyl Compounds; Cerebral Cortex; Chlordiazepoxide; Cyclic AMP; Diazepam; Ethers; Guinea Pigs; Histamine; Hydrazines; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Norepinephrine; Oxazepam; Phosphodiesterase Inhibitors; Pyrazoles; Pyridines; Rats; Species Specificity; Theophylline | 1974 |
Pharmacology of oxazepam (Serax), a new anti-anxiety agent.
Topics: Acetylcholine; Animals; Anticonvulsants; Antidepressive Agents; Appetite; Avoidance Learning; Behavior; Blood Pressure; Cats; Chlordiazepoxide; Diazepam; Dogs; Guinea Pigs; Haplorhini; Histamine H1 Antagonists; Learning; Mice; Nervous System; Oxazepam; Rats | 1965 |
Metabolism of diazepam in isolated perfused liver of rat and mouse.
Topics: Animals; Chromatography, Thin Layer; Diazepam; Liver; Male; Mice; Oxazepam; Perfusion; Rats | 1968 |
A comprehensive scheme for the evaluation of anticonvulsant concentrations in blood using thin-layer chromatography.
Topics: Acetazolamide; Anticonvulsants; Benzazepines; Carbamazepine; Chlordiazepoxide; Chromatography, Thin Layer; Diazepam; Epilepsy; Ethosuximide; Humans; Hydantoins; Mephobarbital; Nitro Compounds; Oxazepam; Phenobarbital; Phenytoin; Primidone; Succinimides; Thiazines | 1971 |
The concentrations of diazepam and its metabolites in the plasma after an acute and chronic administration.
Topics: Anxiety Disorders; Chromatography, Gas; Diazepam; Humans; Methylation; Microsomes, Liver; Oxazepam; Substance-Related Disorders; Time Factors | 1974 |
Letter: Perinatal metabolism of diazepam.
Topics: Diazepam; Female; Humans; Injections, Intravenous; Maternal-Fetal Exchange; Oxazepam; Pregnancy | 1974 |
Comparative evaluation of the central nervous system activity of diazepam and its metabolites (demethyl-diazepam, methyl-oxazepam and oxazepam).
Topics: Animals; Central Nervous System; Dealkylation; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Female; Hexobarbital; Hydroxylation; Mice; Motor Activity; Muscle Relaxants, Central; Muscles; Oxazepam; Pentylenetetrazole; Sleep; Strychnine; Time Factors | 1974 |
[Effects of psychotropic drugs on exploratory behavior of mice (author's transl)].
Topics: Amphetamine; Animals; Behavior, Animal; Chlordiazepoxide; Chlorpromazine; Diazepam; Dose-Response Relationship, Drug; Exploratory Behavior; Female; Haloperidol; Imipramine; Locomotion; Mescaline; Mice; Motor Activity; Oxazepam; Phenobarbital; Psychotropic Drugs; Reserpine; Statistics as Topic | 1974 |
Preselection of animals in studies of anti-anxiety drugs.
Topics: Analysis of Variance; Animals; Behavior, Animal; Chlorpromazine; Dextroamphetamine; Diazepam; Emotions; Hot Temperature; Imipramine; Male; Oxazepam; Rats; Stomach Ulcer; Tranquilizing Agents | 1974 |
[Brief characteristics of different "sedatives"].
Topics: Anthracenes; Antidepressive Agents; Benzodiazepinones; Chlordiazepoxide; Diazepam; Hypnotics and Sedatives; Meprobamate; Oxazepam; Propranolol; Tranquilizing Agents | 1974 |
The effect of psychopharmaca on uropeptic activity.
Topics: Animals; Depression, Chemical; Diazepam; Dibenzothiazepines; Endopeptidases; Haloperidol; Humans; Male; Mesoridazine; Oxazepam; Peptic Ulcer; Rats; Secretory Rate | 1974 |
[Experimental psychology and psychiatric drug therapy. A practical case of medical psychology].
Topics: Achievement; Adult; Atropa belladonna; Attention; Diazepam; Dibenzazepines; Female; Flicker Fusion; Humans; Male; Neurasthenia; Oxazepam; Plants, Medicinal; Plants, Toxic; Psychological Tests; Psychotic Disorders; Somatotypes; Statistics as Topic; Tranquilizing Agents | 1972 |
High pressure liquid chromatography of benzodiazepines: analysis of ketazolam.
Topics: Benzazepines; Benzodiazepines; Chromatography; Diazepam; Half-Life; Ketones; Kinetics; Nitrazepam; Oxazepam; Oxazines; Pressure; Time Factors | 1972 |
[Comparative study on the inductive effect of various benzodiazepines using the pentobarbital sleeping time of the rat].
Topics: Animals; Benzazepines; Chlordiazepoxide; Diazepam; Nitrazepam; Oxazepam; Pentobarbital; Phenobarbital; Rats; Sleep; Structure-Activity Relationship; Time Factors | 1972 |
New horizons in psychopharmacology.
Topics: Animals; Anthracenes; Antidepressive Agents; Anxiety; Benzamides; Benzazepines; Butyrophenones; Chlordiazepoxide; Chlorprothixene; Diazepam; Dibenzothiazepines; Humans; Monoamine Oxidase Inhibitors; Nitrazepam; Oxazepam; Pharmacogenetics; Phenothiazines; Piperidines; Plants, Medicinal; Psychopharmacology; Rauwolfia; Sleep; Tranquilizing Agents | 1972 |
[The pattern in the prescription and sale of benzodiazepines in Västerbotten county].
Topics: Adolescent; Adult; Age Factors; Aged; Child; Chlordiazepoxide; Diazepam; Drug Prescriptions; Drug Utilization; Female; Humans; Male; Middle Aged; Nitrazepam; Oxazepam; Sex Factors; Statistics as Topic; Sweden; Time Factors; Tranquilizing Agents | 1973 |
Diazepam metabolism during chronic medication unbound fraction in plasma, erythrocytes and urine.
Topics: Binding Sites; Buffers; Chromatography, Gas; Chromatography, Thin Layer; Diazepam; Dose-Response Relationship, Drug; Electrons; Erythrocytes; Humans; Indicators and Reagents; Oxazepam; Solvents; Time Factors | 1973 |
The effects of benzodiazepines on the behaviour of mice on a hole-board.
Topics: Adaptation, Psychological; Animals; Behavior, Animal; Benzazepines; Benzene Derivatives; Chlordiazepoxide; Circadian Rhythm; Diazepam; Environment; Ethylamines; Exploratory Behavior; Female; Fluorine; Mice; Nitrazepam; Oxazepam; Time Factors | 1973 |
Drugs and punished responding. I. Rate-dependent effects under multiple schedules.
Topics: Animals; Chlordiazepoxide; Chlorpromazine; Columbidae; Conditioning, Operant; Dextroamphetamine; Diazepam; Dronabinol; Feeding Behavior; Imipramine; Male; Meprobamate; Mescaline; Morphine; Oxazepam; Pentobarbital; Psychopharmacology; Punishment; Reinforcement Schedule; Tetrabenazine | 1973 |
Benzodiazepines and tricyclic antidepressant plasma levels.
Topics: Amitriptyline; Benzazepines; Chlordiazepoxide; Diazepam; Drug Combinations; Drug Interactions; Female; Humans; Male; Nitrazepam; Nortriptyline; Oxazepam; Tranquilizing Agents | 1973 |
[Study of the conditions of absorption of determined drugs in various pharmaceutical oral forms].
Topics: Administration, Oral; Capsules; Chlordiazepoxide; Diazepam; Dosage Forms; Ethambutol; Intestinal Absorption; Isoniazid; Oxazepam; Pharmaceutical Preparations; Solutions; Tablets | 1973 |
[Dissociation of two components of rat behaviour by psychotropic drugs. Utilization for studying anxiolytic drugs].
Topics: Amobarbital; Animals; Benzoxazoles; Chlormezanone; Chlorpromazine; Dextroamphetamine; Diazepam; Ethanol; Exploratory Behavior; Haloperidol; Locomotion; Male; Mephenesin; Meprobamate; Oxazepam; Prazepam; Rats; Tranquilizing Agents | 1973 |
Psychotropic drugs in use today. The role of diazepam in medical practice.
Topics: Anxiety Disorders; Chlordiazepoxide; Depression; Diazepam; Drug Interactions; Drug Utilization; Family Practice; Humans; Hypnotics and Sedatives; Oxazepam; Psychophysiologic Disorders; Substance-Related Disorders; Tranquilizing Agents; United States | 1973 |
[Identification and quantitative determination of biliary metabolites of diazepam in rats].
Topics: Animals; Benzophenones; Bile; Chromatography, Gas; Chromatography, Thin Layer; Diazepam; Oxazepam; Polarography; Rats; Spectrophotometry, Ultraviolet | 1973 |
Letter: Noninterference of oxazepam, tranxene-4306CB, and nordiazepam with serum glucose determinations.
Topics: Benzazepines; Blood Glucose; Carboxylic Acids; Diazepam; Drug Interactions; Humans; Oxazepam | 1973 |
Letter: Perinatal metabolism of diazepam.
Topics: Diazepam; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Milk, Human; Oxazepam; Pregnancy | 1974 |
[Three acute diphenylhydantoin-intoxications (author's transl)].
Topics: Adolescent; Adult; Alcoholic Intoxication; Diazepam; Drug Combinations; Electroencephalography; Epilepsy, Temporal Lobe; Female; Humans; Neurologic Manifestations; Oxazepam; Phenytoin; Poisoning; Propylamines; Suicide | 1974 |
A rapid gas chromatographic method for the determination of diazepam and metabolites in body fluids.
Topics: Benzoates; Body Fluids; Chromatography, Gas; Diazepam; Electrons; Humans; Microchemistry; Oxazepam; Solvents | 1974 |
Letter: Concentrations of diazepam in adipose tissue of children.
Topics: Adipose Tissue; Anesthesia, General; Child; Chromatography, Gas; Diazepam; Humans; Injections, Intravenous; Oxazepam; Time Factors | 1974 |
Anhydrotic effect of benzodiazepines in mice.
Topics: Animals; Benzazepines; Chlordiazepoxide; Depression, Chemical; Diazepam; Mice; Nitrazepam; Oxazepam; Sweating; Tranquilizing Agents | 1974 |
Pharmacology of 7-chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one (lorazepam; Wy 4036).
Topics: Animals; Behavior, Animal; Benzazepines; Blood Pressure; Cats; Chemical Phenomena; Chemistry; Diazepam; Escape Reaction; Haplorhini; Mice; Morphine; Motor Activity; Oxazepam; Rats; Reflex; Reflex, Monosynaptic; Seizures; Tranquilizing Agents | 1971 |
Determination of tranquillizers by GLC in biological fluids.
Topics: Animals; Autoradiography; Barbiturates; Body Fluids; Brain; Carbamates; Carisoprodol; Chemical Phenomena; Chemistry; Chromatography, Gas; Diazepam; Dibenzazepines; Forensic Medicine; Half-Life; Haplorhini; Hydroxyzine; Hypnotics and Sedatives; Kinetics; Male; Meprobamate; Methods; Oxazepam; Structure-Activity Relationship; Tranquilizing Agents | 1971 |
Metabolism of diazepam metabolites in guinea pigs.
Topics: Adipose Tissue; Animals; Brain; Chromatography, Gas; Diazepam; Guinea Pigs; Kinetics; Male; Methylation; Oxazepam | 1972 |
Biliary excretion of conjugated hydroxyl benzodiazepines after administration of several benzodiazepines to rats, guinea pigs, and mice.
Topics: Animals; Bile; Biotransformation; Dealkylation; Diazepam; Guinea Pigs; Half-Life; Hydrolysis; Hydroxylation; Injections, Intravenous; Male; Methylation; Mice; Oxazepam; Rats; Species Specificity | 1972 |
[Characteristics of the development of tolerance to tranquilizers of the benzodiazepine series according to the muscle relaxant and sedative effects].
Topics: Animals; Chlordiazepoxide; Diazepam; Drug Tolerance; Hexobarbital; Male; Mice; Muscles; Nitrazepam; Oxazepam; Rats; Sleep; Tranquilizing Agents | 1972 |
Effect of sprionolactone on pentobarbital anaesthesia, diazepam metabolism and toxicity of spironolactone and furosemide.
Topics: Animals; Diazepam; Drug Antagonism; Furosemide; Male; Mice; Oxazepam; Pentobarbital; Rats; Spironolactone; Stimulation, Chemical; Time Factors | 1972 |
Increased aggression and toxicity in grouped male mice treated with tranquilizing benzodiazepines.
Topics: Aggression; Animals; Behavior, Animal; Diazepam; Dibenzazepines; Female; Humans; Male; Methylation; Necrosis; Oxazepam; Sex Factors; Social Isolation; Tranquilizing Agents; Wounds and Injuries | 1971 |
A simple and reliable conflict procedure for testing anti-anxiety agents.
Topics: Animals; Anxiety; Behavior, Animal; Chlordiazepoxide; Conflict, Psychological; Dextroamphetamine; Diazepam; Humans; Magnesium; Male; Meprobamate; Oxazepam; Pemoline; Pentobarbital; Rats; Scopolamine; Thirst; Tranquilizing Agents | 1971 |
Initial psychopharmacological study of lorazepam (Wy 4036).
Topics: Adult; Anxiety; Anxiety Disorders; Benzazepines; Chlordiazepoxide; Diazepam; Female; Humans; Male; Oxazepam; Sleep Wake Disorders; Tranquilizing Agents | 1971 |
Gas-liquid chromatography and mass spectrometry of various benzodiazepines.
Topics: Benzazepines; Chromatography, Gas; Diazepam; Mass Spectrometry; Methods; Oxazepam | 1971 |
Drugs in the management of anxiety.
Topics: Anxiety; Barbiturates; Chlordiazepoxide; Diazepam; Humans; Oxazepam; Phenothiazines; Propylene Glycols; Tranquilizing Agents | 1971 |
The cathode-ray polarographic determination of diazepam, 7-chloro-1,3-dihydro-I-methyl-5-phenyl-2H-I,4-benzodiazepine-2-one, in human plasma.
Topics: Administration, Oral; Adult; Aged; Chlordiazepoxide; Diazepam; Female; Humans; Injections, Intravenous; Male; Mathematics; Microchemistry; Middle Aged; Oxazepam; Polarography; Radiation; Time Factors | 1971 |
[Thin-layer chromatography for the identification in urgent toxicological analysis of I,4-benzo(f)diazepines used in therapeutic treatment].
Topics: Benzazepines; Chlordiazepoxide; Chromatography, Gas; Chromatography, Thin Layer; Diazepam; Gastric Juice; Hydrolysis; Methods; Oxazepam; Spectrophotometry; Toxicology | 1971 |
Studies on the metabolism of oxazolam. II. Isolation and identification of the metabolites of oxazolam in rats.
Topics: Animals; Benzazepines; Benzophenones; Bile; Brain; Chromatography, Thin Layer; Diazepam; Feces; Glucuronates; Kidney; Liver; Male; Oxazepam; Oxazoles; Rats; Spectrum Analysis; Ultraviolet Rays | 1971 |
Metabolism and anticonvulsant activity of diazepam in guinea pigs.
Topics: Adipose Tissue; Animals; Anticonvulsants; Brain; Chromatography, Gas; Diazepam; Drug Antagonism; Guinea Pigs; Kinetics; Male; Methylation; Oxazepam; Pentylenetetrazole; Seizures; Time Factors; Tremor | 1971 |
Metabolism of diazepam and its metabolites by guinea pig liver microsomes.
Topics: Animals; Diazepam; Guinea Pigs; In Vitro Techniques; Male; Methylation; Microsomes, Liver; Oxazepam | 1971 |
[Psychopharmacological treatment of anxiety].
Topics: Adult; Amitriptyline; Anxiety; Benzazepines; Carbamates; Chlordiazepoxide; Diazepam; Dibenzazepines; Female; Humans; Ketones; Meprobamate; Methotrimeprazine; Nitro Compounds; Oxazepam; Piperidines; Thioridazine | 1971 |
[Titration of benzodiazepine derivatives in water-free medium. 3. On the chemistry and analysis of benzodiazepine derivatives].
Topics: Chemical Phenomena; Chemistry; Chlordiazepoxide; Diazepam; Hypnotics and Sedatives; Methods; Oxazepam; Potentiometry | 1967 |
Chemotherapy in dental practice anti-anxiety agents: 2. Diazepines.
Topics: Chlordiazepoxide; Diazepam; General Practice, Dental; Humans; Oxazepam | 1969 |
The metabolism of diazepam by liver microsomal enzymes of rats and mice.
Topics: Animals; Benzazepines; Diazepam; In Vitro Techniques; Kinetics; Liver; Mice; Microsomes; Oxazepam; Rats | 1969 |
[Control of anxiety by drugs].
Topics: Adult; Aged; Anxiety; Chlordiazepoxide; Diazepam; Female; Humans; Male; Middle Aged; Oxazepam; Phenothiazines | 1969 |
Chemistry and CNS-pharmacological properties of two hydrosoluble benzodiazepine derivatives.
Topics: Animals; Avoidance Learning; Behavior, Animal; Central Nervous System; Chemical Phenomena; Chemistry, Physical; Depression, Chemical; Diazepam; Dibenzazepines; Drug Synergism; Hexobarbital; Locomotion; Male; Methamphetamine; Motor Activity; Oxazepam; Pentylenetetrazole; Rats; Stimulation, Chemical; Time Factors | 1969 |
[Aspects of iatrogenic pharmacology and toxicology at the fetal level].
Topics: Aminopyrine; Amitriptyline; Animals; Anti-Bacterial Agents; Antipyrine; Diazepam; Dogs; Female; Fetal Diseases; Fetus; Glucuronates; Humans; Iatrogenic Disease; Oxazepam; Pregnancy; Rabbits; Rats; Tranquilizing Agents | 1969 |
Studies on the anticonvulsant action of diazepam.
Topics: Animals; Anticonvulsants; Brain; Brain Chemistry; Chromatography, Gas; Diazepam; Mice; Oxazepam; Pentylenetetrazole; Rats; Seizures | 1970 |
Further studies on the long lasting antimetrazol activity of diazepam in mice.
Topics: Animals; Brain Chemistry; Diazepam; Male; Mice; Oxazepam; Pentylenetetrazole | 1970 |
Toxicity of some benzodiazepine compounds with CNS activity.
Topics: Alkaline Phosphatase; Animals; Benzazepines; Blood Chemical Analysis; Blood Glucose; Breeding; Central Nervous System; Chlordiazepoxide; Cholesterol; Diazepam; Diet; Dogs; Female; Fertility; Fetus; Gonads; Kidney Tubules; Liver; Male; Mice; Oxazepam; Pigmentation; Pregnancy; Prostate; Rabbits; Rats; Tranquilizing Agents | 1970 |
Discrimination with "time out" in rats treated with temazepam, diazepam, oxazepam and chlodiazepoxide HCl.
Topics: Animals; Chlordiazepoxide; Diazepam; Discrimination Learning; Oxazepam; Rats; Time Factors; Tranquilizing Agents | 1970 |
The effect of drugs on conditioned alimentary motor reflexes in cats.
Topics: Amphetamine; Animals; Cats; Chlordiazepoxide; Chlorprothixene; Conditioning, Classical; Diazepam; Feeding Behavior; Female; Male; Oxazepam; Physostigmine; Scopolamine | 1970 |
Fragmentation pattern of 1,4-benzodiazepin-2-ones under electron impact.
Topics: Azepines; Diazepam; Electrons; Oxazepam; Spectrum Analysis | 1970 |
A comparison of the effects of some benzodiazepines and other drugs on aggressive and exploratory behaviour in mice and rats.
Topics: Aggression; Animals; Chlordiazepoxide; Diazepam; Electroshock; Exploratory Behavior; Humans; Locomotion; Male; Meprobamate; Mice; Oxazepam; Pentobarbital; Pentylenetetrazole; Rats; Seizures; Tranquilizing Agents | 1970 |
[Effects of diazepam and oxazepam on the long dorsal root reflex].
Topics: Animals; Cats; Diazepam; Evoked Potentials; Oxazepam; Reflex; Spinal Cord; Tranquilizing Agents | 1970 |
Effects of selected drugs on stimulus-bound emotional behavior elicited by hypothalamic stimulation in the cat.
Topics: Animals; Behavior, Animal; Benzazepines; Cats; Chlordiazepoxide; Chlorpromazine; Diazepam; Electric Stimulation; Emotions; Hypothalamus; Imipramine; Oxazepam; Phenobarbital; Tranquilizing Agents; Tranylcypromine | 1970 |
[Derivatives of benzo-(f)-diazepine-1,4 used in therapeutics. I. Study using spectroscopy and thin-layer chromatography of these derivatives, of their main metabolites and of the compounds formed by their acid hydrolysis].
Topics: Benzazepines; Chemical Phenomena; Chemistry; Chlordiazepoxide; Chromatography, Thin Layer; Diazepam; Oxazepam; Spectrum Analysis | 1970 |
Metabolism of 14C-medazepam hydrochloride in dog, rat and man.
Topics: Adipose Tissue; Administration, Oral; Animals; Benzazepines; Biotransformation; Body Weight; Brain Chemistry; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Diazepam; Digestive System; Dogs; Feces; Female; Humans; In Vitro Techniques; Injections, Intravenous; Kidney; Liver; Lung; Male; Middle Aged; Muscles; Myocardium; Oxazepam; Phenols; Rats; Species Specificity | 1970 |
Correlation between the duration of the anticonvulsant activity of diazepam and its physiological disposition in mice.
Topics: Adipose Tissue; Animals; Anticonvulsants; Benzazepines; Brain; Brain Chemistry; Chemical Phenomena; Chemistry; Diazepam; Female; Male; Mice; Muscles; Myocardium; Oxazepam; Pentylenetetrazole; Seizures; Time Factors; Tritium | 1970 |
[The basic criteria for clinical evaluation of the effect of tranquilizers].
Topics: Benactyzine; Bipolar Disorder; Central Nervous System Diseases; Chlordiazepoxide; Diazepam; Epilepsy; Humans; Mental Disorders; Meprobamate; Morpholines; Neurotic Disorders; Oxazepam; Psychophysiologic Disorders; Psychoses, Alcoholic; Psychotic Disorders; Schizophrenia; Tranquilizing Agents | 1970 |
[Clinical differences between diazepam and oxazepam].
Topics: Diazepam; Humans; Mental Disorders; Oxazepam | 1970 |
Effect of phenobarbital on the in vitro metabolism of diazepam in several animal species.
Topics: Animals; Chromatography, Gas; Dealkylation; Diazepam; Fasting; Guinea Pigs; Male; Metabolism; Methylation; Mice; Microsomes, Liver; Mixed Function Oxygenases; Oxazepam; Phenobarbital; Rats; Species Specificity | 1970 |
Species differences in diazepam metabolism. I. Metabolism of diazepam metabolites.
Topics: Adipose Tissue; Animals; Brain; Chromatography, Gas; Diazepam; Male; Mice; Oxazepam; Rats; Species Specificity; Time Factors | 1970 |
Detection and identification of nitrazepam and related compounds by thin-layer chromatography.
Topics: Adult; Animals; Benzazepines; Chlordiazepoxide; Chromatography, Thin Layer; Diazepam; Female; Gastric Mucosa; Humans; Hypnotics and Sedatives; Ketones; Male; Methods; Middle Aged; Nitrazepam; Oxazepam; Rabbits; Suicide | 1970 |
The mink as a psychopharmacological model.
Topics: Aggression; Animals; Chlordiazepoxide; Chlorpromazine; Diazepam; Humans; Male; Meprobamate; Mink; Models, Biological; Oxazepam; Pentobarbital; Tranquilizing Agents | 1970 |
Effects of various drugs on 3,4-dihydroxyphenylalanine (DL-DOPA)-induced excitation (agressive behavior) in mice.
Topics: Aggression; Animals; Antidepressive Agents; Autonomic Agents; Behavior, Animal; Bretylium Compounds; Chlordiazepoxide; Chlorpromazine; Diazepam; Dihydroxyphenylalanine; Drug Antagonism; Haloperidol; Hexobarbital; Humans; Imipramine; Iproniazid; Male; Mice; Morphine; Oxazepam; Reserpine; Tranquilizing Agents; Tranylcypromine; Trifluoperazine | 1970 |
Thermolysis of 1,4-benzodiazepines during gas chromatography and mass spectroscopy.
Topics: Benzazepines; Chemical Phenomena; Chemistry; Chromatography, Gas; Diazepam; Drug Stability; Methods; Oxazepam; Spectrum Analysis; Tranquilizing Agents | 1971 |
[Comparison of the characteristics of the effect of tranquilizing agents under experimental and clinical conditions].
Topics: Animals; Anticonvulsants; Behavior, Animal; Central Nervous System Diseases; Chlordiazepoxide; Depression, Chemical; Diazepam; Drug Synergism; Electroshock; Emotions; Hexobarbital; Humans; Hypnotics and Sedatives; Mental Disorders; Meprobamate; Mice; Morpholines; Movement; Muscle Relaxants, Central; Neurotic Disorders; Orientation; Oxazepam; Pentylenetetrazole; Rats; Schizophrenia; Strychnine; Tranquilizing Agents | 1971 |
Enhancement of amphetamine-induced stereotyped behavior by benzodiazepines.
Topics: Animals; Behavior, Animal; Chlordiazepoxide; Diazepam; Dibenzazepines; Male; Methamphetamine; Motor Activity; Oxazepam; Proadifen; Rats | 1971 |
[Pharmacologic research on the dimethylaminoethanol salt of 7-chloro-1,3-dihydro-3-hemisuccinyloxy-5-phenyl-2H-1,4-benzodiazepin-2-one].
Topics: Animals; Behavior, Animal; Caffeine; Diazepam; Drug Synergism; Male; Methamphetamine; Nutritional Physiological Phenomena; Oxazepam; Pentobarbital; Rabbits; Rats; Strychnine; Tetrazolium Salts; Tremorine | 1967 |
[Experimental neurophysiologic study on the mechansim of action of benzodiazepines].
Topics: Animals; Cats; Cerebral Cortex; Diazepam; Electric Stimulation; Electroencephalography; Evoked Potentials; Eye Movements; Hippocampus; Hypnotics and Sedatives; Mesencephalon; Oxazepam; Sleep | 1967 |
Studies on the anticonvulsant properties of some benzodiazepines. (Chlordiazepoxide, diazepam, oxazepam).
Topics: Action Potentials; Animals; Anticonvulsants; Chlordiazepoxide; Diazepam; Electroencephalography; Female; Male; Morphine; Nicotine; Oxazepam; Phenobarbital; Phenytoin; Rabbits; Seizures; Strychnine | 1967 |
Metabolism of diazepam in vitro.
Topics: Animals; Brain; Chromatography, Thin Layer; Diazepam; Dogs; Female; In Vitro Techniques; Liver; Male; Oxazepam; Phenobarbital; Rats; Tritium | 1968 |
A method for gas chromatographic determination of benzodiazepines.
Topics: Chromatography, Gas; Diazepam; Methods; Oxazepam | 1968 |
Species difference in diazepam metabolism and anticonvulsant effect.
Topics: Animals; Anticonvulsants; Brain Chemistry; Diazepam; Injections, Intraperitoneal; Injections, Intravenous; Mice; Oxazepam; Pentylenetetrazole; Rats; Species Specificity | 1968 |
["Paradoxical" psychic effects of benzodiazepines].
Topics: Anxiety Disorders; Chlordiazepoxide; Diazepam; Humans; Oxazepam; Psychoses, Substance-Induced; Tranquilizing Agents | 1968 |
Detection of impurities in medical 1,4-benzodiazepines and related compounds by thin-layer chromatography.
Topics: Chlordiazepoxide; Chromatography, Thin Layer; Diazepam; Dosage Forms; Drug Contamination; Hypnotics and Sedatives; Oxazepam; Solvents | 1968 |
A new benzodiazepine: electroencephalographic studies of its anticonvulsant activity in non-anesthetized, non-curarized rabbits.
Topics: Action Potentials; Amygdala; Animals; Anticonvulsants; Diazepam; Dibenzazepines; Electrocardiography; Electroencephalography; Electroshock; Hypnotics and Sedatives; Hypothalamus; Oxazepam; Pentylenetetrazole; Rabbits; Reticular Formation; Strychnine; Thalamus | 1969 |
Metabolism of diazepam in dogs: transformation to oxazepam.
Topics: Animals; Antidepressive Agents; Chromatography, Thin Layer; Diazepam; Dogs; Glucuronates; Infrared Rays; Oxazepam; Spectrum Analysis; Urine | 1965 |
Today's drugs. Benzodiazepines.
Topics: Chlordiazepoxide; Diazepam; Humans; Hypnotics and Sedatives; Oxazepam; Tranquilizing Agents | 1967 |
Clinical pharmacology of psychotropic drugs.
Topics: Animals; Behavior; Chlordiazepoxide; Diazepam; Humans; Neurotic Disorders; Oxazepam; Tranquilizing Agents | 1967 |
Influences of benzodiazepines on hypothalamically elicited emotional responses in the rabbit.
Topics: Animals; Diazepam; Dose-Response Relationship, Drug; Emotions; Female; Hypothalamic Area, Lateral; Hypothalamus, Middle; Male; Oxazepam; Rabbits; Receptors, GABA-A; Self Stimulation | 1984 |
An integrated approach to iatrogenic drug abuse in a closed delivery system.
Topics: Adult; Aged; Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Doxepin; Drug and Narcotic Control; Drug Prescriptions; Female; Flurazepam; Germany, West; Hospitals, Military; Hospitals, Public; Humans; Iatrogenic Disease; Male; Medication Systems, Hospital; Meprobamate; Middle Aged; Oxazepam; Substance-Related Disorders; United States | 1980 |
Determination of some benzodiazepines and metabolites in serum, urine and saliva by high-performance liquid chromatography.
Topics: Anti-Anxiety Agents; Chromatography, High Pressure Liquid; Diazepam; Humans; Mathematics; Nordazepam; Oxazepam; Saliva; Temazepam | 1980 |
Improving benzodiazepine prescribing in family practice through review and education.
Topics: Adolescent; Adult; Age Factors; Aged; Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Drug Prescriptions; Family Practice; Female; Flurazepam; Humans; Male; Middle Aged; Oxazepam | 1981 |
Benzodiazepine withdrawal.
Topics: Anti-Anxiety Agents; Anxiety; Diazepam; Drug Tolerance; Humans; Lorazepam; Oxazepam; Sleep Initiation and Maintenance Disorders; Substance Withdrawal Syndrome; Time Factors | 1981 |
[Pharmacokinetic of benzodiazepines in old age].
Topics: Adult; Aged; Aging; Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Half-Life; Humans; Lorazepam; Metabolic Clearance Rate; Middle Aged; Nitrazepam; Nordazepam; Oxazepam | 1981 |
Aspects of the interaction of thyroxine and its binding serum proteins with 1,4-benzodiazepine tranquillizers.
Topics: Anti-Anxiety Agents; Autoradiography; Binding, Competitive; Chlordiazepoxide; Diazepam; Electrophoresis, Polyacrylamide Gel; Humans; Male; Nordazepam; Oxazepam; Temazepam; Thyroxine; Thyroxine-Binding Proteins | 1981 |
Benzodiazepine prescription to middle-aged women: it is done indiscriminately by family physicians?
Topics: Age Factors; Anti-Anxiety Agents; Canada; Diazepam; Female; Humans; Life Change Events; Marriage; Middle Aged; Oxazepam; Physician's Role; Sex Factors; Stress, Psychological; Substance-Related Disorders | 1982 |
Limited in vivo bioassays on some benzodiazepines: lack of experimental initiating or promoting effect of the benzodiazepine tranquillizers diazepam, clorazepate, oxazepam and lorazepam.
Topics: 2-Acetylaminofluorene; Animals; Anti-Anxiety Agents; Biological Assay; Carcinogens; Clorazepate Dipotassium; Diazepam; Lorazepam; Male; Oxazepam; Rats; Rats, Inbred F344; Time Factors | 1982 |
Rapid gas chromatographic measurement of diazepam and its metabolites desmethyldiazepam, oxazepam, and 3-hydroxydiazepam (temazepam) in small samples of plasma.
Topics: Anti-Anxiety Agents; Biotransformation; Chromatography, Gas; Diazepam; Humans; Nordazepam; Oxazepam; Temazepam | 1982 |
Potentiation of the antitumor activity of tegafur in sarcoma 180-bearing mice by chlordiazepoxide, diazepam and oxazepam.
Topics: Animals; Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Drug Synergism; Fluorouracil; Male; Mice; Oxazepam; Sarcoma 180; Tegafur | 1983 |
Withdrawal after substitution of a short-acting for a long-acting benzodiazepine.
Topics: Anti-Anxiety Agents; Anxiety; Chronic Disease; Delayed-Action Preparations; Diazepam; Flurazepam; Half-Life; Humans; Oxazepam; Sleep Initiation and Maintenance Disorders; Substance Withdrawal Syndrome; Temazepam | 1983 |
Effects of chlordiazepoxide, diazepam and oxazepam on the antitumor activity, the lethality and the blood level of active metabolites of cyclophosphamide and cyclophosphamide oxidase activity in mice.
Topics: Animals; Anti-Anxiety Agents; Antineoplastic Agents; Biotransformation; Carcinoma, Ehrlich Tumor; Chlordiazepoxide; Cyclophosphamide; Cytochrome P-450 Enzyme System; Diazepam; Drug Interactions; Male; Mice; Mixed Function Oxygenases; Oxazepam; Oxidoreductases; Proteins | 1983 |
[Methods of detection and determination of neurotropic drugs in the blood of persons driving motor vehicles. II. Detection and determination of various benzodiazepine derivatives in the human blood by gas chromatography].
Topics: Anti-Anxiety Agents; Automobile Driving; Chlordiazepoxide; Chromatography, Gas; Diazepam; Humans; Medazepam; Oxazepam | 1983 |
[Comparative clinical toxicology of 5 benzodiazepine derivatives].
Topics: Adult; Anti-Anxiety Agents; Bromazepam; Child; Coma; Diazepam; Dose-Response Relationship, Drug; Female; Flunitrazepam; Humans; Lorazepam; Male; Metabolic Clearance Rate; Oxazepam; Prognosis; Respiratory Insufficiency; Suicide, Attempted | 1984 |
Fetal toxicity of benzodiazepines in rats.
Topics: Abnormalities, Drug-Induced; Animals; Anti-Anxiety Agents; Chlordiazepoxide; Clonazepam; Diazepam; Female; Fetal Resorption; Fetus; Male; Nitrazepam; Oxazepam; Pregnancy; Rats; Rats, Inbred Strains | 1984 |
Subacute benzodiazepine treatment: observations on behavioural tolerance and withdrawal.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Conditioning, Psychological; Diazepam; Drinking Behavior; Drug Tolerance; Humans; Male; Mice; Motor Activity; Oxazepam; Pentylenetetrazole; Rats; Seizures; Substance Withdrawal Syndrome; Triazolam | 1984 |
The influence of cyclobarbital and diazepam on drug metabolism in vitro and their binding to cytochrome P-450.
Topics: Animals; Barbital; Barbiturates; Cytochrome P-450 Enzyme System; Diazepam; Ethylmorphine; Hexobarbital; In Vitro Techniques; Liver; Male; Morphine Derivatives; Oxazepam; Rats; Rats, Inbred Strains | 1984 |
Progress report from the Division of Behavioral Biology, the Johns Hopkins University School of Medicine.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Butorphanol; Codeine; Conditioning, Operant; Diazepam; Discrimination Learning; Humans; Morphine; Nalbuphine; Narcotics; Oxazepam; Pentazocine; Pupil; Self Administration | 1984 |
Blood concentrations of diazepam and its metabolites in children and neonates with tetanus.
Topics: Child; Diazepam; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Nordazepam; Oxazepam; Tetanus | 1983 |
In vitro interaction of diazepam and oxazepam with pancuronium and suxamethonium.
Topics: Animals; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; Muscle Contraction; Neuromuscular Junction; Nordazepam; Oxazepam; Pancuronium; Rats; Rats, Inbred Strains; Succinylcholine; Temazepam | 1984 |
The contribution of the active metabolites to the tolerance developing to diazepam in man: relationship to bioassayed serum benzodiazepine levels.
Topics: Adult; Benzodiazepines; Biological Assay; Diazepam; Double-Blind Method; Drug Tolerance; Female; Humans; Male; Nordazepam; Oxazepam; Psychomotor Performance | 1984 |
Dose effect and preference comparison of diazepam and oxazepam.
Topics: Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Humans; Oxazepam; Psychomotor Performance | 1984 |
Differences in diazepam and oxazepam.
Topics: Aged; Diazepam; Half-Life; Humans; Kinetics; Oxazepam; Sleep Stages | 1984 |
Comparison of diazepam and oxazepam: preference, liking and extent of abuse.
Topics: Adult; Diazepam; Humans; Male; Middle Aged; Oxazepam; Reinforcement, Psychology; Substance-Related Disorders; Time Factors | 1984 |
Structure activity relationships of selected benzodiazepines as anticonvulsants to local anesthetics.
Topics: Anesthetics, Local; Animals; Anticonvulsants; Benzodiazepines; Diazepam; Lidocaine; Male; Mepivacaine; Mice; Nitrazepam; Nordazepam; Oxazepam; Prilocaine; Seizures; Structure-Activity Relationship; Temazepam | 1980 |
Influence of cimetidine on the pharmacokinetics of desmethyldiazepam and oxazepam.
Topics: Adult; Cimetidine; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Female; Guanidines; Humans; Kinetics; Liver; Male; Nordazepam; Oxazepam | 1980 |
Radioimmunoassay of benzodiazepines.
Topics: Benzodiazepines; Chlordiazepoxide; Clonazepam; Diazepam; Flurazepam; Humans; Microchemistry; Nitrazepam; Nordazepam; Oxazepam; Radioimmunoassay | 1982 |
Anticonvulsant potency of unmetabolized diazepam.
Topics: Animals; Anticonvulsants; Brain; Diazepam; Male; Mice; Nordazepam; Oxazepam; Pentylenetetrazole; Time Factors | 1982 |
Abstinence syndrome from therapeutic doses of oxazepam.
Topics: Adult; Anxiety; Depression; Depressive Disorder; Diazepam; Fasciculation; Fear; Humans; Male; Oxazepam; Panic; Paresthesia; Propranolol; Substance Withdrawal Syndrome | 1983 |
Significance of apparent half-lives of a metabolite with a higher elimination rate than its parent drug.
Topics: Diazepam; Glucuronates; Half-Life; Humans; Kidney Diseases; Metabolic Clearance Rate; Oxazepam; Pharmaceutical Preparations; Sulfamethoxazole | 1982 |
Specific binding of racemic oxazepam esters to rat brain synaptosomes and the influence of bioactivation by esterases.
Topics: Animals; Biotransformation; Brain; Diazepam; Esterases; Esters; In Vitro Techniques; Isoflurophate; Oxazepam; Rats; Stereoisomerism; Synaptosomes | 1981 |
Systematic review of the benzodiazepines. Guidelines for data sheets on diazepam, chlordiazepoxide, medazepam, clorazepate, lorazepam, oxazepam, temazepam, triazolam, nitrazepam, and flurazepam. Committee on the Review of Medicines.
Topics: Benzodiazepines; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Flurazepam; Humans; Lorazepam; Medazepam; Nitrazepam; Oxazepam; Safety; Substance Withdrawal Syndrome; Substance-Related Disorders; Temazepam; Triazolam | 1980 |
Development and preliminary application of high-performance liquid chromatographic assay of urinary metabolites of diazepam in humans.
Topics: Chromatography, High Pressure Liquid; Diazepam; Humans; Nordazepam; Oxazepam; Reference Values; Reproducibility of Results; Temazepam | 1995 |
Precipitated withdrawal in squirrel monkeys after repeated daily oral administration of alprazolam, diazepam, flunitrazepam or oxazepam.
Topics: Administration, Oral; Alprazolam; Animals; Behavior, Animal; Diazepam; Dose-Response Relationship, Drug; Drug Tolerance; Female; Flumazenil; Flunitrazepam; Male; Muscle Relaxation; Oxazepam; Saimiri; Sleep; Substance Withdrawal Syndrome; Substance-Related Disorders; Tremor | 1995 |
Identification of parent benzodiazepines by gas chromotography/mass spectroscopy (GC/MS) from urinary extracts treated with B-glucuronidase.
Topics: Alprazolam; Benzodiazepines; Chlordiazepoxide; Clonazepam; Diazepam; Gas Chromatography-Mass Spectrometry; Glucuronidase; Humans; Lorazepam; Oxazepam; Triazolam | 1995 |
Alcohol and benzodiazepines generate anxiety, panic and phobias.
Topics: Adult; Aged; Alcohol Drinking; Alcoholism; Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Female; Humans; Lorazepam; Male; Middle Aged; Oxazepam; Panic Disorder; Phobic Disorders; Substance Withdrawal Syndrome | 1995 |
Effects of hypothermia on the elimination of ethanol, diazepam and oxazepam in rat liver slice incubations.
Topics: Animals; Body Temperature; Cold Temperature; Diazepam; Ethanol; Linear Models; Liver; Male; Oxazepam; Rats; Rats, Sprague-Dawley; Time Factors | 1995 |
Determination of oxazepam and diazepam in body fluids by HPLC.
Topics: Chromatography, High Pressure Liquid; Clonazepam; Diazepam; Humans; Oxazepam; Regression Analysis; Reproducibility of Results; Sensitivity and Specificity | 1993 |
Pharmacokinetics of nordiazepam in physical dependence and precipitated abstinence in dogs.
Topics: Administration, Oral; Animals; Blood Proteins; Diazepam; Dogs; Female; Flumazenil; Hydrolysis; Injections, Intravenous; Nordazepam; Oxazepam; Protein Binding; Substance Withdrawal Syndrome; Substance-Related Disorders | 1993 |
Kinetics of sequential metabolism. II. Formation and metabolism of nordiazepam and oxazepam from diazepam in the perfused murine liver.
Topics: Animals; Diazepam; Kinetics; Male; Mice; Microsomes, Liver; Nordazepam; Oxazepam; Perfusion | 1993 |
Alcohol withdrawal: a nationwide survey of inpatient treatment practices.
Topics: Adrenergic beta-Antagonists; Alcoholism; Barbiturates; Benzodiazepines; Chlordiazepoxide; Clonidine; Data Collection; Diazepam; Drug Administration Schedule; Hypnotics and Sedatives; Inpatients; Lorazepam; Oxazepam; Phenytoin; Substance Withdrawal Syndrome | 1995 |
Flumazenil, diazepam, nordiazepam and oxazepam interactions on plasma protein binding.
Topics: Animals; Anti-Anxiety Agents; Biotransformation; Blood Proteins; Diazepam; Dogs; Drug Interactions; Flumazenil; In Vitro Techniques; Nordazepam; Oxazepam; Protein Binding | 1995 |
[Kinetics of elimination of diazepam after intravenous injection in horses].
Topics: Adjuvants, Anesthesia; Animals; Diazepam; Half-Life; Horses; Hypnotics and Sedatives; Injections, Intravenous; Metabolic Clearance Rate; Oxazepam | 1997 |
The effect of chronic benzodiazepines exposure on body weight in rats.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Body Weight; Diazepam; Dose-Response Relationship, Drug; Female; Flumazenil; Flunitrazepam; GABA Modulators; Male; Nordazepam; Oxazepam; Rats; Rats, Sprague-Dawley; Sex Factors; Time Factors; Weight Gain | 1998 |
Rapid and simple chromatographic method for the determination of diazepam and its major metabolites in human plasma and urine.
Topics: Calibration; Chromatography, High Pressure Liquid; Clonazepam; Diazepam; Humans; Nordazepam; Oxazepam; Reference Values; Temazepam | 1998 |
Simultaneous extraction of selected benzodiazepines and benzodiazepine-glucuronides from urine by immunoadsorption.
Topics: Anti-Anxiety Agents; Diazepam; Glucuronates; Humans; Immunosorbent Techniques; Immunosorbents; Lorazepam; Oxazepam; Temazepam | 1998 |
Plasma and CSF benzodiazepine receptor ligand concentrations in cirrhotic patients with hepatic encephalopathy: relationship to severity of encephalopathy and to pharmaceutical benzodiazepine intake.
Topics: Animals; Benzodiazepines; Binding, Competitive; Cell Fractionation; Cerebellum; Chronic Disease; Clonazepam; Diazepam; Flumazenil; GABA Modulators; Hepatic Encephalopathy; Humans; Isoquinolines; Liver Cirrhosis; Oxazepam; Radioligand Assay; Rats; Receptors, GABA-A; Tritium | 1998 |
Determination of benzodiazepines in human urine and plasma with solvent modified solid phase micro extraction and gas chromatography; rationalisation of method development using experimental design strategies.
Topics: Alprazolam; Anti-Anxiety Agents; Benzodiazepines; Chromatography, Gas; Diazepam; Flunitrazepam; Humans; Hydrogen-Ion Concentration; Models, Chemical; Nordazepam; Oxazepam; Research Design | 1998 |
Effect of benzodiazepines on the epithelial and neuronal high-affinity glutamate transporter EAAC1.
Topics: Amino Acid Transport System X-AG; Animals; Anti-Anxiety Agents; Binding Sites; Carrier Proteins; CHO Cells; Clozapine; Cricetinae; Cricetulus; Diazepam; Epithelial Cells; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid; Ion Transport; Lorazepam; Medazepam; Nerve Tissue Proteins; Neurons; Oocytes; Oxazepam; Recombinant Fusion Proteins; Sodium; Symporters; Xenopus laevis | 1999 |
Flow-injection fluorimetric determination of 1,4-benzodiazepines in pharmaceutical formulations after acid hydrolysis.
Topics: Anti-Anxiety Agents; Autoanalysis; Benzodiazepines; Calibration; Diazepam; Flow Injection Analysis; Hydrogen-Ion Concentration; Hydrolysis; Indicators and Reagents; Nitrazepam; Oxazepam; Regression Analysis; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1999 |
Electrospray ionization gas-phase electrophoresis under ambient conditions and it's potential or high-speed separations.
Topics: Alprazolam; Anti-Anxiety Agents; Combinatorial Chemistry Techniques; Diazepam; Electrophoresis; Equipment Design; Herbicides; Nitrazepam; Oxazepam; Prazepam; Time Factors; Triazines | 2001 |
The simultaneous determination of diazepam and its three metabolites in dog plasma by high-performance liquid chromatography with mass spectroscopy detection.
Topics: Animals; Anti-Anxiety Agents; Chromatography, High Pressure Liquid; Diazepam; Dogs; Mass Spectrometry; Nordazepam; Oxazepam; Reproducibility of Results; Temazepam | 2001 |
Benzodiazepines differently modulate EAAT1/GLAST and EAAT2/GLT1 glutamate transporters expressed in CHO cells.
Topics: Animals; Aspartic Acid; Biological Transport; CHO Cells; Cricetinae; Cricetulus; Diazepam; Dose-Response Relationship, Drug; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Humans; Kinetics; Nerve Tissue Proteins; Neuroglia; Oxazepam; Recombinant Fusion Proteins; Transfection | 2002 |
Pharmacological and endocrinological characterisation of stress-induced hyperthermia in singly housed mice using classical and candidate anxiolytics (LY314582, MPEP and NKP608).
Topics: Adrenocorticotropic Hormone; Analysis of Variance; Animals; Anti-Anxiety Agents; Benzodiazepines; Body Temperature; Bridged Bicyclo Compounds; Buspirone; Chlordiazepoxide; Clobazam; Corticosterone; Diazepam; Ethanol; Hyperthermia, Induced; Male; Mice; Mice, Inbred ICR; Oxazepam; Piperidines; Pyridines; Quinolines; Reproducibility of Results; Stress, Physiological | 2002 |
Effects of diazepam and its metabolites on nocturnal melatonin secretion in the rat pineal and Harderian glands. A comparative in vivo and in vitro study.
Topics: Animals; Circadian Rhythm; Diazepam; Harderian Gland; In Vitro Techniques; Male; Melatonin; Nordazepam; Oxazepam; Perfusion; Pineal Gland; Rats; Rats, Wistar; Temazepam | 2003 |
Effects of benzodiazepines on enzymes metabolizing drugs. IV. Effect of diazepam and oxazepam on hepatic microsomal drug metabolizing enzymes in rats exposed to high environmental temperature.
Topics: Animals; Anti-Anxiety Agents; Depression, Chemical; Diazepam; Environment; Hot Temperature; Male; Microsomes, Liver; Mixed Function Oxygenases; Oxazepam; Pharmaceutical Preparations; Rats | 1990 |
Development and validation of a liquid chromatographic/electrospray ionization mass spectrometric method for the quantitation of prazepam and its main metabolites in human plasma.
Topics: Calibration; Chromatography, Liquid; Diazepam; Humans; Molecular Structure; Nordazepam; Oxazepam; Prazepam; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization | 2005 |
Fast in vivo microextraction: a new tool for clinical analysis.
Topics: Animals; Biocompatible Materials; Blood Chemical Analysis; Blood Specimen Collection; Calibration; Chemistry Techniques, Analytical; Chromatography, Liquid; Diazepam; Dogs; Mass Spectrometry; Nordazepam; Oxazepam; Polyethylene Glycols; Polymers; Pyrroles; Silicon Dioxide | 2006 |
On the mechanism of hepatocarcinogenesis of benzodiazepines: evidence that diazepam and oxazepam are CYP2B inducers in rats, and both CYP2B and CYP4A inducers in mice.
Topics: Animals; Benzodiazepines; Blotting, Western; Body Weight; Carcinogens; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Diazepam; Hypnotics and Sedatives; Immunohistochemistry; Isoenzymes; Lauric Acids; Liver Neoplasms; Male; Mice; Microsomes, Liver; Nitrophenols; Organ Size; Oxazepam; Phenobarbital; Rats; Rats, Sprague-Dawley | 2006 |
The detection of sedatives in hair and nail samples using tandem LC-MS-MS.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Azabicyclo Compounds; Benzodiazepines; Chromatography, Liquid; Clobazam; Clonazepam; Diazepam; Female; Forensic Pathology; Hair; Humans; Hypnotics and Sedatives; Male; Mass Spectrometry; Midazolam; Middle Aged; Nails; Oxazepam; Piperazines; Predictive Value of Tests; Rape; Temazepam; Triazolam | 2007 |
Cytochrome P450 (CYP) inhibition screening: comparison of three tests.
Topics: Citalopram; Cytochrome P-450 Enzyme Inhibitors; Diazepam; Enzyme Inhibitors; Fluoxetine; Humans; Oxazepam; Propranolol; Sotalol | 2006 |
A sensitive and selective method for the detection of diazepam and its main metabolites in urine by gas chromatography-tandem mass spectrometry.
Topics: Benzodiazepinones; Diazepam; Gas Chromatography-Mass Spectrometry; Nordazepam; Oxazepam; Reproducibility of Results; Tandem Mass Spectrometry; Time Factors | 2007 |
Pharmacological analysis of the effects of benzodiazepines on punished schedule-induced polydipsia in rats.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Chlordiazepoxide; Diazepam; Dose-Response Relationship, Drug; Drinking; Electroshock; Fear; Flumazenil; Food Deprivation; GABA Modulators; Imidazoles; Male; Oxazepam; Punishment; Pyrimidines; Rats; Rats, Wistar; Receptors, GABA-A; Reinforcement Schedule | 2007 |
Small human hepatocytes in rotary culture for treatment of alcohol addicts? A pilot study.
Topics: Alcoholism; Cell Count; Cell Culture Techniques; Cell Line; Culture Media; Cytochrome P-450 Enzyme System; Diazepam; Hepatocytes; Humans; Hypnotics and Sedatives; L-Lactate Dehydrogenase; Lactic Acid; Liver Diseases, Alcoholic; Liver, Artificial; Microscopy, Confocal; Oxazepam; Pilot Projects; Urea; Xenobiotics | 2007 |
A rapid fluorimetric screening method for the 1,4-benzodiazepines: determination of their metabolite oxazepam in urine.
Topics: Clorazepate Dipotassium; Diazepam; Humans; Oxazepam; Sensitivity and Specificity; Spectrometry, Fluorescence | 2007 |
Two compartment model of diazepam biotransformation in an organotypical culture of primary human hepatocytes.
Topics: Anti-Inflammatory Agents; Antithyroid Agents; Biotransformation; Cell Separation; Chlorodiphenyl (54% Chlorine); Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dexamethasone; Diazepam; Enzyme Induction; Hepatocytes; Humans; Hypnotics and Sedatives; Models, Biological; Models, Statistical; Nordazepam; Organ Culture Techniques; Oxazepam; Phenobarbital; Temazepam | 2009 |
[Simultaneous determination of 5 sedative hypnotics in human plasma by reversed phase high-performance liquid chromatography].
Topics: Alprazolam; Chromatography, High Pressure Liquid; Diazepam; Estazolam; Humans; Hypnotics and Sedatives; Nitrazepam; Oxazepam | 2009 |
Simultaneous analysis of diazepam and its metabolites in rat plasma and brain tissue by HPLC-UV and SPE.
Topics: Animals; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Diazepam; Nordazepam; Oxazepam; Rats; Reproducibility of Results; Solid Phase Extraction; Spectrophotometry, Ultraviolet; Temazepam | 2009 |
Quantitation of benzodiazepines in blood and urine using gas chromatography-mass spectrometry (GC-MS).
Topics: Alprazolam; Benzodiazepines; Diazepam; Gas Chromatography-Mass Spectrometry; Humans; Lorazepam; Nordazepam; Oxazepam; Solid Phase Extraction; Triazolam | 2010 |
Biotransformation of diazepam in a clinically relevant flat membrane bioreactor model using primary porcine hepatocytes.
Topics: Adult; Animals; Bioreactors; Biotransformation; Cells, Cultured; Culture Media; Culture Media, Serum-Free; Diazepam; Female; Hepatocytes; Humans; Inactivation, Metabolic; Liver, Artificial; Male; Nordazepam; Oxazepam; Swine; Temazepam; Young Adult | 2011 |
Pharmacokinetics of the cytochrome P-450 substrates phenytoin, theophylline, and diazepam in healthy Greyhound dogs.
Topics: Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Diazepam; Dogs; Female; Fluorescence Polarization Immunoassay; Gas Chromatography-Mass Spectrometry; Injections, Intravenous; Male; Nordazepam; Oxazepam; Phenytoin; Theophylline | 2012 |
Environmental occurrence, fate and transformation of benzodiazepines in water treatment.
Topics: Benzodiazepines; Biodegradation, Environmental; Bioreactors; Bromazepam; Chromatography, Gas; Chromatography, High Pressure Liquid; Diazepam; Oxazepam; Pilot Projects; Slovenia; Waste Disposal, Fluid; Water Pollutants, Chemical; Water Purification | 2012 |
Direct determination of diazepam and its glucuronide metabolites in human whole blood by μElution solid-phase extraction and liquid chromatography-tandem mass spectrometry.
Topics: Chromatography, Liquid; Diazepam; Forensic Toxicology; Humans; Hypnotics and Sedatives; Limit of Detection; Nordazepam; Oxazepam; Reproducibility of Results; Solid Phase Extraction; Tandem Mass Spectrometry; Temazepam | 2013 |
Urinary diazepam metabolite distribution in a chronic pain population.
Topics: Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Chronic Pain; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Diazepam; Drug Interactions; Esomeprazole; Female; Fluoxetine; Humans; Male; Methadone; Nordazepam; Oxazepam; Retrospective Studies; Specimen Handling; Temazepam | 2014 |
Influence of central nervous system-acting drugs on results of cognitive testing in geriatric inpatients.
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Antidepressive Agents; Benzodiazepines; Central Nervous System Agents; Cognition Disorders; Diazepam; Female; Hospitalization; Humans; Hypnotics and Sedatives; Lorazepam; Male; Mental Status Schedule; Oxazepam | 2014 |
A mixed MDPV and benzodiazepine intoxication in a chronic drug abuser: determination of MDPV metabolites by LC-HRMS and discussion of the case.
Topics: Adult; Alprazolam; Benzodiazepines; Benzodioxoles; Chlordiazepoxide; Chromatography, Liquid; Diazepam; Humans; Hypnotics and Sedatives; Male; Mass Spectrometry; Nordazepam; Oxazepam; Psychotropic Drugs; Pyrrolidines; Substance-Related Disorders; Synthetic Cathinone; Temazepam | 2014 |
Production of monoclonal antibody against clonazepam for immunoassay of benzodiazepine drugs in swine tissues.
Topics: Animals; Antibodies, Monoclonal; Benzodiazepines; Clonazepam; Diazepam; Drug Residues; Flunitrazepam; Food Contamination; Haptens; Immunoassay; Kidney; Limit of Detection; Liver; Meat; Mice; Mice, Inbred BALB C; Muscles; Oxazepam; Serum Albumin; Swine; Tissue Distribution | 2015 |
Low doses of ethanol markedly potentiate the anti-seizure effect of diazepam in a mouse model of difficult-to-treat focal seizures.
Topics: Animals; Anticonvulsants; Brain; Diazepam; Disease Models, Animal; Drug Compounding; Drug Synergism; Electroencephalography; Epilepsy, Temporal Lobe; Ethanol; Female; Kainic Acid; Mice; Nordazepam; Oxazepam; Seizures; Solvents; Temazepam; Water | 2014 |
A comparative study of primary secondary amino (PSA) and multi-walled carbon nanotubes (MWCNTs) as QuEChERS absorbents for the rapid determination of diazepam and its major metabolites in fish samples by high-performance liquid chromatography-electrospray
Topics: Adsorption; Animals; Chromatography, High Pressure Liquid; Diazepam; Fishes; Food Contamination; Nanotubes, Carbon; Nordazepam; Oxazepam; Seafood; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Temazepam | 2016 |
Is long-term use of benzodiazepine a risk for cancer?
Topics: Benzodiazepines; Carcinogens; Case-Control Studies; Chlordiazepoxide; Clonazepam; Diazepam; Female; Humans; Logistic Models; Longitudinal Studies; Male; Medazepam; Middle Aged; Nitrazepam; Oxazepam; Proportional Hazards Models | 2015 |
ELISA Detection of Phenazepam, Etizolam, Pyrazolam, Flubromazepam, Diclazepam and Delorazepam in Blood Using Immunalysis® Benzodiazepine Kit.
Topics: Adult; Benzodiazepines; Cross Reactions; Diazepam; Enzyme-Linked Immunosorbent Assay; Fatal Outcome; Forensic Toxicology; Humans; Limit of Detection; Male; Oxazepam; Reagent Kits, Diagnostic; Substance Abuse Detection; Tranquilizing Agents; Young Adult | 2016 |
A 5-year follow-up study of users of benzodiazepine: starting with diazepam versus oxazepam.
Topics: Adult; Anti-Anxiety Agents; Anxiety; Depression; Diazepam; Dose-Response Relationship, Drug; Drug Prescriptions; Female; Follow-Up Studies; Humans; Male; Middle Aged; Norway; Oxazepam; Prescription Drug Misuse; Prevalence; Proportional Hazards Models; Risk Factors; Substance-Related Disorders | 2016 |
Characterization of equine cytochrome P450: role of CYP3A in the metabolism of diazepam.
Topics: Animals; Chlorocebus aethiops; COS Cells; Cytochrome P-450 CYP3A; Diazepam; Horses; Hypnotics and Sedatives; Male; Microsomes, Liver; Nordazepam; Oxazepam; Phylogeny; Protein Isoforms; Rats; Rats, Sprague-Dawley; Species Specificity; Temazepam | 2016 |
Interrupted Time Series Analysis of the Effect of Rescheduling Alprazolam in Australia: Taking Control of Prescription Drug Use.
Topics: Adult; Aged; Alprazolam; Antidepressive Agents; Antipsychotic Agents; Australia; Benzodiazepines; Diazepam; Drug and Narcotic Control; Drug Substitution; Female; Humans; Hypnotics and Sedatives; Interrupted Time Series Analysis; Male; Middle Aged; Oxazepam; Practice Patterns, Physicians' | 2016 |
Deposition of diazepam and its metabolites in hair following a single dose of diazepam.
Topics: Adult; Asian People; Chromatography, Liquid; Diazepam; Female; Hair; Healthy Volunteers; Humans; Hypnotics and Sedatives; Male; Nordazepam; Oxazepam; Tandem Mass Spectrometry; Temazepam; Young Adult | 2017 |
Investigation of the effect of mobile phase composition on selectivity using a solvent-triangle based approach in achiral SFC.
Topics: 1-Propanol; Acetonitriles; Benzodiazepines; Chromatography, Supercritical Fluid; Diazepam; Drug Contamination; Ethanol; Furans; Hydrogen Bonding; Lorazepam; Methanol; Multivariate Analysis; Organic Chemicals; Oxazepam; Principal Component Analysis; Reproducibility of Results; Silicon Dioxide; Solvents; Temazepam | 2017 |
Pentobarbital in the context of possible suicides: Analysis of a Case.
Topics: Adult; Central Nervous System Depressants; Diazepam; Ethanol; Gastrointestinal Contents; Humans; Male; Nordazepam; Oxazepam; Pentobarbital; Suicide; Temazepam | 2017 |
Site-, Technique-, and Time-Related Aspects of the Postmortem Redistribution of Diazepam, Methadone, Morphine, and their Metabolites: Interest of Popliteal Vein Blood Sampling.
Topics: Adult; Blood Specimen Collection; Chromatography, Liquid; Diazepam; Female; Femoral Vein; Forensic Toxicology; Humans; Male; Methadone; Middle Aged; Morphine; Morphine Derivatives; Nordazepam; Oxazepam; Popliteal Vein; Postmortem Changes; Subclavian Vein; Young Adult | 2017 |
Entomotoxicology in burnt bodies: a case of maternal filicide-suicide by fire.
Topics: Adult; Animals; Automobiles; Burns; Carbon Monoxide Poisoning; Carboxyhemoglobin; Child; Child, Preschool; Diazepam; Diptera; Feeding Behavior; Female; Fires; Gasoline; Homicide; Humans; Hypnotics and Sedatives; Kidney; Larva; Liver; Male; Nordazepam; Oxazepam; Postmortem Changes; Suicide | 2017 |
An observational study of benzodiazepine prescription during inpatient alcohol detoxification for patients with vs. without chronic pretreatment with high-dosage baclofen.
Topics: Administration, Oral; Adult; Alcohol Drinking; Alcoholism; Baclofen; Diazepam; Female; GABA Modulators; GABA-B Receptor Agonists; Humans; Inpatients; Male; Middle Aged; Oxazepam; Retrospective Studies; Substance Withdrawal Syndrome; Time Factors; Treatment Outcome | 2018 |
A silica fiber coated with a ZnO-graphene oxide nanocomposite with high specific surface for use in solid phase microextraction of the antiepileptic drugs diazepam and oxazepam.
Topics: Adsorption; Anticonvulsants; Diazepam; Graphite; Humans; Hydrogen-Ion Concentration; Nanocomposites; Oxazepam; Salts; Silicon Dioxide; Solid Phase Microextraction; Surface Properties; Zinc Oxide | 2018 |
Associations of Benzodiazepines, Z-Drugs, and Other Anxiolytics With Subsequent Dementia in Patients With Affective Disorders: A Nationwide Cohort and Nested Case-Control Study.
Topics: Aged; Aged, 80 and over; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Azabicyclo Compounds; Benzodiazepines; Bipolar Disorder; Case-Control Studies; Comorbidity; Dementia; Denmark; Depressive Disorder; Depressive Disorder, Major; Diazepam; Dose-Response Relationship, Drug; Female; Humans; Hypnotics and Sedatives; Incidence; Logistic Models; Male; Middle Aged; Mood Disorders; Odds Ratio; Oxazepam; Piperazines; Proportional Hazards Models; Protective Factors; Risk Factors | 2020 |
Postmortem Analysis of Benzodiazepines in Human Bone by Gas Chromatography-Mass Spectrometry.
Topics: Alprazolam; Autopsy; Benzodiazepines; Chromatography, Liquid; Clonazepam; Diazepam; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Liquid-Liquid Extraction; Lorazepam; Nordazepam; Oxazepam; Tandem Mass Spectrometry | 2021 |
Is the unique benzodiazepine structure interacting with CYP enzymes to affect steroid synthesis in vitro?
Topics: Adrenal Cortex Hormones; Adrenal Glands; Alprazolam; Androgens; Benzodiazepines; Diazepam; Endocrine Disruptors; Humans; Molecular Docking Simulation; Oxazepam; Receptors, Androgen; Receptors, GABA-A; Steroid 17-alpha-Hydroxylase; Steroid 21-Hydroxylase; Steroids | 2021 |
[Acute benzodiazepine withdrawal delirium].
Topics: Alcohol Withdrawal Delirium; Benzodiazepines; Delirium; Diazepam; Humans; Male; Middle Aged; Oxazepam; Substance Withdrawal Syndrome | 2022 |