diazepam and naltrexone

diazepam has been researched along with naltrexone in 41 studies

Research

Studies (41)

Timeframe	Studies, this research(%)	All Research%
pre-1990	10 (24.39)	18.7374
1990's	9 (21.95)	18.2507
2000's	15 (36.59)	29.6817
2010's	7 (17.07)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B	1
Topliss, JG; Yoshida, F	1
Chang, TK; Ensom, MH; Kiang, TK	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Chance, WT; Krynock, GM; Rosecrans, JA; White, AC	1
Brocco, MJ; Killam, KF; Robinson, CA	1
Mediratta, PK; Puri, S; Ray, A; Sen, P	1
Chaves, ML; Izquierdo, I; Jardim, CP; Pezzin, S	1
Maier, SF	1
Carino, MA; Chinn, C; Horita, A	1
Bailey, C; Brewer, C; Rezae, H	1
Armfield, A; Cunnick, JE; Lysle, DT; Rabin, BS	1
del Río, J; Fernández-Tomé, MP; González, Y; Sánchez-Franco, F	1
Chance, WT	1
Brown, DR; Holtzman, SG; Locke, KW	1
Herling, S	1
Cooper, SJ	1
Maier, SF; Minor, TR	1
Clyde, VL; Ramsay, EC; Sleeman, JM	1
Pruett, SB; Wu, WJ	1
Misawa, M; Nagase, H; Suzuki, T; Tsuda, M	1
Camara, P; Davidson, D; Fitz, E; Rosen, S; Swift, R	1
Katayama, S; Kohno, H; Ohkubo, Y; Ohuchi, Y	1
Goto, K; Ishige, A; Komatsu, Y; Omiya, Y	1
Easterling, KW; Holtzman, SG; Plovnick, RM	1
Ballachey, BE; McCormick, C; Monson, DH	1
Berridge, KC; Cooper, SJ; Reynolds, SM; Richardson, DK	1
Burghardt, PR; Wilson, MA	1
Kaneko, C; Kuzumaki, N; Matsuzawa, K; Miyoshi, K; Nagumo, Y; Nakajima, M; Nanjo, K; Narita, M; Suzuki, T; Yamazaki, M	1
Mascagni, F; McDonald, AJ; Primeaux, SD; Wilson, MA; Wilson, SP	1
Sharma, B; Singh, SM	1
Brissett, DI; van Rijn, RM; Whistler, JL	1
Akbari, HA; Cahill, CM; Carroll, FI; Evans, CJ; Lutfy, K; Pradhan, AA; Roberts, KW; Taylor, AM; Walwyn, W	1
Besirli, A; Eşel, E; Özsoy, S; Turan, T	1
Lindsey, AM; Prinssen, EP; Rice, KC; Saccone, PA; Sulima, A; Wichmann, J; Woods, JH; Zelenock, KA	1

Reviews

4 review(s) available for diazepam and naltrexone

Article	Year
UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacology & therapeutics, 2005, Volume: 106, Issue:1 Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic	2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Autoanalgesia: opiate and non-opiate mechanisms. Neuroscience and biobehavioral reviews, 1980,Spring, Volume: 4, Issue:1 Topics: Animals; Central Nervous System; Conditioning, Classical; Diazepam; Electroshock; Emotions; Endorphins; Fear; Hypophysectomy; Hypothalamus; Male; Mice; Naloxone; Naltrexone; Norepinephrine; Pain; Raphe Nuclei; Rats; Reaction Time; Receptors, Opioid; Serotonin; Spinal Cord	1980
Unintentional rapid opioid detoxification: case report. Psychiatria Danubina, 2009, Volume: 21, Issue:1 Topics: Adult; Consciousness Disorders; Critical Care; Diazepam; Drug Interactions; Emergency Service, Hospital; Epilepsy, Generalized; Humans; Illicit Drugs; Infusions, Intravenous; Male; Naltrexone; Narcotic Antagonists; Narcotics; Neurologic Examination; Opioid-Related Disorders; Private Practice; Substance Abuse Detection; Substance Withdrawal Syndrome	2009

Trials

2 trial(s) available for diazepam and naltrexone

Article	Year
Diazepam inhibits retroactive interference of memory in humans: pretreatment with naltrexone does not alter this effect. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1990, Volume: 23, Issue:5 Topics: Adolescent; Adult; Analysis of Variance; Diazepam; Double-Blind Method; Female; Humans; Male; Memory; Middle Aged; Naltrexone	1990
Naltrexone effects on diazepam intoxication and pharmacokinetics in humans. Psychopharmacology, 1998, Volume: 135, Issue:3 Topics: Adult; Affect; Aged; Anti-Anxiety Agents; Central Nervous System Depressants; Diazepam; Ethanol; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Neuropsychological Tests; Nordazepam; Psychomotor Performance	1998

Other Studies

35 other study(ies) available for diazepam and naltrexone

Article	Year
Predicting blood-brain barrier permeation from three-dimensional molecular structure. Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11 Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate. Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24 Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility	2010
Autoanalgesia: acquisition, blockade and relationship to opiate binding. European journal of pharmacology, 1979, Oct-15, Volume: 58, Issue:4 Topics: Analgesia; Animals; Brain; Conditioning, Classical; Diazepam; Enkephalins; Etorphine; In Vitro Techniques; Male; Naltrexone; Narcotics; Rats; Reaction Time; Spinal Cord	1979
Evaluation of narcotic and narcotic antagonist interactions in primates. Annals of the New York Academy of Sciences, 1976, Volume: 281 Topics: Animals; Cyclazocine; Dextroamphetamine; Diazepam; Drug Interactions; Ethanol; Female; Haplorhini; Humans; Macaca mulatta; Male; Methadone; Methadyl Acetate; Morphine; Morphine Dependence; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Phenytoin; Secobarbital; Self Administration	1976
Effects of stress on immune responsiveness, gastric ulcerogenesis and plasma corticosterone in rats: modulation by diazepam and naltrexone. Indian journal of experimental biology, 1991, Volume: 29, Issue:3 Topics: Animals; Antibody Formation; Corticosterone; Diazepam; Male; Naltrexone; Rats; Rats, Inbred Strains; Stomach Ulcer; Stress, Physiological	1991
Role of fear in mediating shuttle escape learning deficit produced by inescapable shock. Journal of experimental psychology. Animal behavior processes, 1990, Volume: 16, Issue:2 Topics: Animals; Arousal; Conditioning, Classical; Cues; Diazepam; Electroshock; Escape Reaction; Fear; Helplessness, Learned; Male; Mental Recall; Motor Activity; Naltrexone; Rats; Rats, Inbred Strains; Transfer, Psychology	1990
Codeine produces a cholinergically mediated analeptic effect in rats and rabbits. Pharmacology, biochemistry, and behavior, 1988, Volume: 30, Issue:1 Topics: Animals; Brain; Central Nervous System Stimulants; Choline; Codeine; Diazepam; Drug Interactions; Male; Naltrexone; Pentobarbital; Rabbits; Rats; Rats, Inbred Strains; Synaptosomes	1988
Opioid withdrawal and naltrexone induction in 48-72 hours with minimal drop-out, using a modification of the naltrexone-clonidine technique. The British journal of psychiatry : the journal of mental science, 1988, Volume: 153 Topics: Adolescent; Adult; Clonidine; Diazepam; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Naltrexone; Narcotics; Substance Withdrawal Syndrome; Time Factors	1988
Shock-induced modulation of lymphocyte responsiveness and natural killer activity: differential mechanisms of induction. Brain, behavior, and immunity, 1988, Volume: 2, Issue:2 Topics: Animals; Concanavalin A; Diazepam; Electroshock; Killer Cells, Natural; Lymphocyte Activation; Lymphocytes; Male; Mitogens; Naltrexone; Phytohemagglutinins; Rats; Rats, Inbred Lew; Spleen; Stress, Physiological	1988
Antagonism of diazepam-induced feeding in rats by antisera to opioid peptides. Life sciences, 1984, Sep-24, Volume: 35, Issue:13 Topics: Animals; beta-Endorphin; Dexamethasone; Diazepam; Endorphins; Enkephalin, Methionine; Feeding Behavior; Immune Sera; Male; Naloxone; Naltrexone; Pituitary Gland; Rats; Rats, Inbred Strains; Thyrotropin-Releasing Hormone	1984
Effects of opiate antagonists and putative mu- and kappa-agonists on milk intake in rat and squirrel monkey. Pharmacology, biochemistry, and behavior, 1982, Volume: 17, Issue:6 Topics: Animals; Buprenorphine; Cyclazocine; Diazepam; Diprenorphine; Drinking; Ethylketocyclazocine; Etorphine; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Saimiri; Taste	1982
Naltrexone blocks the response-latency increasing effects but not the discriminative effects of diazepam in rats. European journal of pharmacology, 1983, Mar-18, Volume: 88, Issue:1 Topics: Animals; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Drug Interactions; Male; Naloxone; Naltrexone; Rats; Rats, Inbred F344; Reaction Time; Receptors, Cell Surface; Receptors, GABA-A	1983
Palatability-induced drinking after administration of morphine, naltrexone and diazepam in the non-deprived rat. Substance and alcohol actions/misuse, 1982, Volume: 3, Issue:5 Topics: Animals; Diazepam; Dose-Response Relationship, Drug; Drinking; Male; Morphine; Muridae; Naloxone; Naltrexone; Taste	1982
Dissociation of interference with the speed and accuracy of escape produced by inescapable shock. Behavioral neuroscience, 1993, Volume: 107, Issue:1 Topics: Animals; Arousal; Attention; Carbolines; Chlordiazepoxide; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Electroshock; Escape Reaction; Fear; Naltrexone; Orientation; Problem Solving; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, GABA-A; Restraint, Physical	1993
Immobilization of black bears (Ursus americanus) with orally administered carfentanil citrate. Journal of wildlife diseases, 1995, Volume: 31, Issue:3 Topics: Administration, Oral; Analgesics, Opioid; Animals; Diazepam; Female; Fentanyl; Immobilization; Male; Muscle Relaxants, Central; Muscle, Skeletal; Naltrexone; Narcotic Antagonists; Oxygen; Respiration; Ursidae	1995
Suppression of splenic natural killer cell activity in a mouse model for binge drinking. II. Role of the neuroendocrine system. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 278, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alcoholism; Animals; Azides; Benzodiazepines; Carbolines; Catecholamines; Corticosterone; Diazepam; Disease Models, Animal; Female; GABA-A Receptor Agonists; Glucocorticoids; Immunity, Cellular; Immunity, Innate; Killer Cells, Natural; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mifepristone; Nadolol; Naltrexone; Neurosecretory Systems; Oxidopamine; Phentolamine; Picrotoxin; Propranolol; Receptors, GABA-A; Spleen; Sympathetic Nervous System	1996
Involvement of the opioid system in the anxiolytic effect of diazepam in mice. European journal of pharmacology, 1996, Jun-20, Volume: 307, Issue:1 Topics: Analgesics, Non-Narcotic; Animals; Anti-Anxiety Agents; Anticonvulsants; Body Temperature; Conflict, Psychological; Diazepam; Drug Interactions; Dynorphins; Male; Mice; Mice, Inbred Strains; Motor Activity; Naltrexone; Narcotic Antagonists; Peptide Fragments; Receptors, Opioid; Receptors, Opioid, kappa	1996
Possible neural mechanisms involved in footshock stress-induced enhancement of exploratory behavior in mice. Biological & pharmaceutical bulletin, 1999, Volume: 22, Issue:4 Topics: Animals; Atropine; Central Nervous System; Diazepam; Dizocilpine Maleate; Electric Stimulation; Exploratory Behavior; Haloperidol; Male; Mianserin; Mice; Naltrexone; Phentolamine; Propranolol; Stress, Physiological	1999
Changes in analgesia-producing mechanism of repeated cold stress loading in mice. Pharmacology, biochemistry, and behavior, 2000, Volume: 65, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Anti-Anxiety Agents; Anxiety; Cold Temperature; Diazepam; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Male; Mice; Morphine; Naltrexone; Narcotic Antagonists; Pain Threshold; Receptors, Opioid, kappa; Receptors, Opioid, mu; Stress, Physiological	2000
Acute opioid but not benzodiazepine dependence in rats responding for intracranial self-stimulation. Psychopharmacology, 2000, Volume: 148, Issue:3 Topics: Animals; Benzodiazepines; Brain; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Male; Morphine; Naltrexone; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Self Stimulation; Substance-Related Disorders	2000
Chemical anesthesia of northern sea otters (Enhydra lutris): results of past field studies. Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2001, Volume: 32, Issue:2 Topics: Anesthesia; Anesthetics, Combined; Anesthetics, Intravenous; Animals; Azaperone; Body Temperature; Diazepam; Female; Fentanyl; Heart Rate; Hypnotics and Sedatives; Immobilization; Logistic Models; Male; Naloxone; Naltrexone; Narcotic Antagonists; Otters; Respiration; Seizures; Time Factors; Tremor	2001
Endogenous opioids are necessary for benzodiazepine palatability enhancement: naltrexone blocks diazepam-induced increase of sucrose-'liking'. Pharmacology, biochemistry, and behavior, 2005, Volume: 81, Issue:3 Topics: Analysis of Variance; Animals; Behavior, Animal; Benzodiazepines; Diazepam; Food Preferences; Male; Naltrexone; Narcotic Antagonists; Opioid Peptides; Quinine; Rats; Rats, Sprague-Dawley; Solutions; Sucrose; Taste; Taste Threshold; Time Factors	2005
Microinjection of naltrexone into the central, but not the basolateral, amygdala blocks the anxiolytic effects of diazepam in the plus maze. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2006, Volume: 31, Issue:6 Topics: Acetylcholinesterase; Amygdala; Analysis of Variance; Animals; Anti-Anxiety Agents; Behavior, Animal; Central Nervous System Depressants; Diazepam; Drug Interactions; Ethanol; Immunohistochemistry; Male; Maze Learning; Microinjections; Naltrexone; Narcotic Antagonists; Rats; Rats, Long-Evans	2006
Chronic pain induces anxiety with concomitant changes in opioidergic function in the amygdala. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2006, Volume: 31, Issue:4 Topics: Amygdala; Analgesics, Opioid; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Benzamides; Chronic Disease; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Freund's Adjuvant; Guanosine 5'-O-(3-Thiotriphosphate); Injections, Intraventricular; Male; Maze Learning; Mice; Mice, Inbred C57BL; Naltrexone; Narcotic Antagonists; Narcotics; Pain; Pain Measurement; Piperazines; Protein Binding; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reaction Time; Sciatica; Somatostatin; Sulfur Isotopes; Time Factors; Tranquilizing Agents	2006
The role of delta opioid receptors in the anxiolytic actions of benzodiazepines. Pharmacology, biochemistry, and behavior, 2006, Volume: 85, Issue:3 Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Diazepam; Enkephalins; Male; Maze Learning; Naltrexone; Rats; Rats, Long-Evans; Receptors, GABA-A; Receptors, Opioid, delta	2006
Dual efficacy of delta opioid receptor-selective ligands for ethanol drinking and anxiety. The Journal of pharmacology and experimental therapeutics, 2010, Volume: 335, Issue:1 Topics: Alcohol Deterrents; Alcohol Drinking; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Benzamides; Diazepam; Ligands; Mice; Mice, Inbred C57BL; Mice, Knockout; Naltrexone; Narcotic Antagonists; Piperazines; Quinolines; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Opioid, delta; Substance Withdrawal Syndrome	2010
Anti-nociception mediated by a κ opioid receptor agonist is blocked by a δ receptor agonist. British journal of pharmacology, 2015, Volume: 172, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Behavior, Animal; Benzamides; Diazepam; Etorphine; Female; Hot Temperature; Male; Mice, Inbred C57BL; Mice, Knockout; Naltrexone; Nociceptin Receptor; Nociception; Piperazines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Stress, Psychological	2015
Hypothalamic-pituitary-adrenal axis response to oral naltrexone in alcoholics during early withdrawal. Pharmacopsychiatry, 2014, Volume: 47, Issue:4-5 Topics: Administration, Oral; Adrenocorticotropic Hormone; Adult; Diazepam; Ethanol; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Male; Middle Aged; Naltrexone; Pituitary-Adrenal System; Substance Withdrawal Syndrome	2014
Characterization of the Discriminative Stimulus Effects of a NOP Receptor Agonist Ro 64-6198 in Rhesus Monkeys. The Journal of pharmacology and experimental therapeutics, 2016, Volume: 357, Issue:1 Topics: Analgesics, Opioid; Animals; Benzimidazoles; Conditioning, Operant; Diazepam; Discrimination, Psychological; Dose-Response Relationship, Drug; Female; Fentanyl; GABA Modulators; Imidazoles; Macaca mulatta; Male; Naltrexone; Narcotic Antagonists; Nociceptin Receptor; Pain Measurement; Piperidines; Receptors, Opioid; Spiro Compounds	2016