diazepam and isoniazid

diazepam has been researched along with isoniazid in 86 studies

Research

Studies (86)

Timeframe	Studies, this research(%)	All Research%
pre-1990	44 (51.16)	18.7374
1990's	20 (23.26)	18.2507
2000's	13 (15.12)	29.6817
2010's	8 (9.30)	24.3611
2020's	1 (1.16)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Campillo, NE; Guerra, A; Páez, JA	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bajusz, D; Balogh, GT; Dargó, G; Müller, J; Simon, K	1
Biggio, G; Costa, E; Guidotti, A	3
Javid, MJ; Stone, WE	1
Costa, E; Guidotti, A; Mao, CC; Suria, A	1
Costa, E; Guidotti, A; Naik, SR	1
Guidotti, A; Kurosawa, A; Naik, SR	1
Dinnendahl, V; Gumulka, SW; Schönhöfer, PS	1
Costa, E; Guidotti, A; Mao, CC	1
Kapitonov, NI; Sokolova, GB; Ziia, AV	1
Korein, J	1
Chin, L; Herrier, RN; Laird, HE; Picchioni, AL; Sievers, ML	1
Beubler, E; Lembeck, F	1
Bear, ES; Hoffman, PF; Randal, RE; Siegel, SR	1
Bernasconi, R; Leonhardt, T; Martin, P; Portet, C; Schmutz, M; Steulet, AF	1
Bhattacharya, A; Chawla, R; Gurnani, A; Kundra, P	1
Diamantis, W; Gels, M; Gordon, R; Sofia, RD	1
Li, DX; Sun, AY; Wang, YL	1
Biggio, G; Concas, A; Sanna, E; Serra, M	1
Biggio, G; Concas, A; Sanna, E; Santoro, G; Serra, M	1
Biggio, G; Concas, A; Foddi, C; Sanna, E; Serra, M	1
Biggio, G; Concas, A; Mascia, MP; Sanna, E; Santoro, V; Serra, M	1
Biggio, G; Sanna, E; Serra, M	1
Krishnamoorthy, MS; Paul, V	1
Furukawa, T; Kushiku, K	1
Benavides, J; Camelin, JC; Flamand, F; Gueremy, C; Le Fur, G; Legrand, JJ; Mitrani, N; Uzan, A	1
Brownstein, D; Parish, RA	1
Laporte, AM; Soubrié, P; Thiébot, MH	1
Xu, NS; Zhang, JR; Zheng, WA	1
Baltzer, V; Bernasconi, R; Jones, RS; Klein, M; Maître, L; Martin, P; Portet, C; Schmutz, M	1
Kutt, H; Penry, JK	1
Linnoila, M; Mattila, MJ	2
Kutt, H; Verebely, K	1
Saad, SF	1
Cardini, C; Mazzaracchio, F; Quercia, V	1
Cardini, C; Stacchini, A	1
Hoffman, JE; Johnson, PB; Mottram, PE	1
Eriksson, K; Mellström, G; Sandell, E	1
Maksy, M; Nathan, R; Ness, R; Pahl, MV; Vaziri, ND	1
Hamon, M; Hery, F; Jobert, A; Montastruc, JL; Soubrie, P; Thiebot, MH	1
Rumiantsev, VB; Sokolova, GB; Ziia, AV	1
Kageyama, H; Kurosawa, A	1
Zetler, G	1
Koe, BK; Lebel, LA	1
Costa, E; Ferrero, P; Guidotti, A	1
Doherty, T	1
Dengler, HJ; Greenblatt, DJ; Ochs, HR; Roberts, GM	1
Czuczwar, SJ; Kleinrok, Z; Turski, L	1
Korein, J; Kupersmith, M; Levidow, L; Lieberman, A	1
Lahori, UC; Sharma, DB	1
Blowey, DL; Johnson, D; Verjee, Z	1
Morel, E; Perrault, G; Sanger, DJ; Zivkovic, B	1
Biggio, G; Concas, A; Dazzi, L; Maciocco, E; Mascia, MP; Ongini, E; Santoro, G	1
Biggio, G; Ghiani, CA; Motzo, C; Porceddu, ML; Serra, M	1
Barret, GH; Buck, WB; Holding, J; Knight, MK; Villar, D	1
Biggio, G; Cuccu, R; Ghiani, CA; Murgia, A; Pisu, MG; Serra, M	1
Jenck, F; Martin, JR; Moreau, JL; Pieri, L	1
Griebel, G; Perrault, G; Sanger, DJ; Schoemaker, H; Tan, S	1
Anic, T; Aralica, G; Dodig, G; Duplancie, B; Jelovac, N; Marovic, A; Mise, S; Perovic, D; Petek, M; Pigac, B; Prkacin, I; Rucman, R; Sebecic, B; Seiwerth, S; Sikiric, P; Slobodnjak, Z; Stancic-Rokotov, D; Turkovic, B; Ziger, T; Zoricic, I	1
Kulkarni, SK; Naidu, PS	1
Long, CF; Lou, YC; Zhang, Y	1
Anlar, O; Atas, B; Caksen, H; Erol, M; Odabas, D; Tuncer, O	1
Buznego, MT; Pérez-Saad, H	1
Biggio, G; Busonero, F; Maciocco, E; Mostallino, MC; Mura, ML; Pisu, MG; Sanna, E; Serra, M; Talani, G	1
Ekici, NZ; Kefi, A; Sakarya, M; Topcu, I; Yentur, EA	1
Cyran, J; Graf, J; Radunz, W; Scheffold, N	1
Bailabar, T; Bum, EN; Hiana, IR; Moto, FC; Nkainsa, LA; Rakotonirina, A; Rakotonirina, SV; Seke Etet, PF; Seyni, P; Taiwe, GS	1
Afzal, M; Anwar, F; Gupta, G; Kazmi, I	1
Dilrukshi, MDSA; Gnanathasan, CA; Ratnayake, CAP	1
Biggio, G; Concas, A; Marino, G; Minei, R; Mostallino, MC; Pannaccione, A; Pierobon, P; Santoro, G	1
Biggio, G; Concas, A; Marino, G; Minei, R; Mostallino, MC; Pierobon, P; Porcu, P	1
Fushiki, T; Hanai, K; Imaizumi, M; Inoue, K; Kuroda, K; Manabe, Y; Sako, N; Yamamoto, T	1

Reviews

5 review(s) available for diazepam and isoniazid

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
New concepts on the mechanism of action of benzodiazepines. Life sciences, 1975, Jul-15, Volume: 17, Issue:2 Topics: Animals; Benzodiazepines; Cerebellum; Chlordiazepoxide; Cyclic AMP; Diazepam; gamma-Aminobutyric Acid; Ganglia, Autonomic; Glycine; Humans; Isoniazid; Medulla Oblongata; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Receptors, Drug; Seizures; Sensory Receptor Cells; Spinal Cord; Strychnine; Substantia Nigra	1975
Different mechanisms mediating the decrease of cerebellar cGMP elicited by haloperidol and diazepam. Advances in biochemical psychopharmacology, 1976, Volume: 15 Topics: Animals; Apomorphine; Cerebellum; Cyclic GMP; Diazepam; gamma-Aminobutyric Acid; Haloperidol; Harmaline; Isoniazid; Kinetics; Rats	1976
Usefulness of blood levels of antiepileptic drugs. Archives of neurology, 1974, Volume: 31, Issue:5 Topics: Anticonvulsants; Carbamazepine; Chloramphenicol; Chlordiazepoxide; Chlorpromazine; Chromatography, Gas; Dextropropoxyphene; Diazepam; Dicumarol; Disulfiram; Drug Interactions; Epilepsy; Ethosuximide; Humans; Isoniazid; Methylphenidate; Phenethylamines; Phenobarbital; Phenylbutazone; Phenytoin; Primidone; Prochlorperazine; Sulfamethizole; Sulfaphenazole; Thiazines	1974
Treatment of acute isoniazid overdose in dogs. Veterinary and human toxicology, 1995, Volume: 37, Issue:5 Topics: Administration, Oral; Animals; Anticonvulsants; Antitubercular Agents; Cats; Diazepam; Dog Diseases; Dogs; Drug Overdose; Female; Isoniazid; Male; Pyridoxine; Seizures	1995

Other Studies

81 other study(ies) available for diazepam and isoniazid

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Human Serum Albumin Binding in a Vial: A Novel UV-pH Titration Method To Assist Drug Design. Journal of medicinal chemistry, 2020, 02-27, Volume: 63, Issue:4 Topics: Binding Sites; Chemistry, Pharmaceutical; Drug Design; Humans; Hydrogen-Ion Concentration; Molecular Docking Simulation; Pharmaceutical Preparations; Protein Binding; Serum Albumin, Human; Spectrophotometry, Ultraviolet; Titrimetry	2020
Pharmacologically induced changes in the 3':5'-cyclic guanosine monophosphate content of rat cerebellar cortex: difference between apomorphine, haloperidol and harmaline. The Journal of pharmacology and experimental therapeutics, 1977, Volume: 200, Issue:1 Topics: Alkaloids; Animals; Apomorphine; Cerebellar Cortex; Cyclic AMP; Cyclic GMP; Diazepam; Guanylate Cyclase; Haloperidol; Harmaline; Isoniazid; Male; Pyridines; Rats; Trihexyphenidyl	1977
Benzodiazepines and phenobarbital as antagonists of dissimilar chemical convulsants. Epilepsia, 1978, Volume: 19, Issue:4 Topics: 3-Mercaptopropionic Acid; Animals; Anti-Anxiety Agents; Anticonvulsants; Bicuculline; Chlordiazepoxide; Convulsants; Diazepam; gamma-Aminobutyric Acid; Isoniazid; Male; Mice; Nitrazepam; Pentylenetetrazole; Phenobarbital; Picrotoxin; Therapeutic Equivalency	1978
Central GABA receptor agonists: comparison of muscimol and baclofen. Neuropharmacology, 1976, Volume: 15, Issue:8 Topics: Aminobutyrates; Animals; Anticonvulsants; Baclofen; Cerebellum; Cyclic GMP; Diazepam; gamma-Aminobutyric Acid; Harmaline; Isoniazid; Male; Motor Activity; Muscle Tonus; Mycotoxins; Oxazoles; Phenobarbital; Quaternary Ammonium Compounds; Rats; Receptors, Drug; Strychnine; Substance P	1976
Possible role of gamma aminobutyric acid (GABA) in the regulation of cAMP system in rat anterior pituitary. Psychoneuroendocrinology, 1977, Volume: 2, Issue:3 Topics: Aminobutyrates; Animals; Baclofen; Cyclic AMP; Diazepam; gamma-Aminobutyric Acid; Hypothalamus; Isoniazid; Isoxazoles; Male; Nipecotic Acids; Pargyline; Picrotoxin; Pituitary Gland, Anterior; Protein Kinases; Rats; Reserpine	1977
Regulation of 3', 5'-cyclic guanosine monophosphate content in deep cerebellar nuclei. Neuroscience, 1977, Volume: 2, Issue:1 Topics: Animals; Cerebellar Nuclei; Cyclic GMP; Diazepam; gamma-Aminobutyric Acid; Haloperidol; Harmaline; Isoniazid; Male; Morphine; Pyridines; Rats; Receptors, Neurotransmitter	1977
The effect of naloxone on cerebellar cGMP content. A possible GABA-antagonistic action? Naunyn-Schmiedeberg's archives of pharmacology, 1979, Volume: 306, Issue:2 Topics: Animals; Cerebellum; Cyclic GMP; Diazepam; GABA Antagonists; Isoniazid; Male; Mice; Naloxone; Pentobarbital; Time Factors	1979
Evidence for an involvement of GABA in the mediation of the cerebellar cGMP decrease and the anticonvulsant action diazepam. Naunyn-Schmiedeberg's archives of pharmacology, 1975, Volume: 289, Issue:4 Topics: Aminobutyrates; Animals; Anti-Anxiety Agents; Anticonvulsants; Barbiturates; Cerebellum; Cyclic AMP; Cyclic GMP; Diazepam; Drug Interactions; gamma-Aminobutyric Acid; Isoniazid; Male; Pentylenetetrazole; Phenytoin; Picrotoxin; Rats; Strychnine	1975
[Possible pharmacological correction of adverse experimental reactions to isoniazid]. Problemy tuberkuleza, 1979, Issue:5 Topics: Animals; Antidotes; Antitubercular Agents; Brain; Diazepam; Isoniazid; Male; Mice; Pyridoxine	1979
Treatment questioned in familial spasmodic torticollis. Neurology, 1977, Volume: 27, Issue:9 Topics: Adult; Diazepam; Female; Glutamine; Haloperidol; Humans; Isoniazid; Male; Torticollis	1977
Evaluation of diazepam and pyridoxine as antidotes to isoniazid intoxication in rats and dogs. Toxicology and applied pharmacology, 1978, Volume: 45, Issue:3 Topics: Animals; Antidotes; Diazepam; Dogs; Drug Therapy, Combination; Isoniazid; Male; Pyridoxine; Rats; Seizures; Species Specificity; Time Factors	1978
Convulsions induced by hyperbaric oxygen: inhibition by phenobarbital, diazepam and baclofen. Naunyn-Schmiedeberg's archives of pharmacology, 1977, Volume: 297, Issue:1 Topics: Aminobutyrates; Animals; Baclofen; Diazepam; Female; gamma-Aminobutyric Acid; Glycine; Hyperbaric Oxygenation; Isoniazid; Male; Mice; Phenobarbital; Rats; Seizures; Strychnine	1977
Suicidal ingestion of isoniazid: an uncommon cause of metabolic acidosis and seizures. Southern medical journal, 1976, Volume: 69, Issue:1 Topics: Acidosis; Adolescent; Adult; Bicarbonates; Diazepam; Diuresis; Female; Humans; Infusions, Parenteral; Isoniazid; Seizures; Suicide, Attempted	1976
Effects of benzodiazepine receptor ligands with different intrinsic activities on seizures induced by inhibition of GAD. Epilepsy research. Supplement, 1992, Volume: 8 Topics: Animals; Anti-Anxiety Agents; Carbolines; Diazepam; Flumazenil; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Hippocampus; Isoniazid; Male; Mice; Mice, Inbred Strains; Pyrazoles; Reaction Time; Receptors, GABA-A; Seizures	1992
Acute isoniazid poisoning. Anaesthesia, 1992, Volume: 47, Issue:9 Topics: Acute Disease; Adult; Diazepam; Female; Humans; Intermittent Positive-Pressure Ventilation; Isoniazid; Male; Pyridoxine; Suicide, Attempted; Thiopental	1992
Interaction of felbamate and diazepam against maximal electroshock seizures and chemoconvulsants in mice. Pharmacology, biochemistry, and behavior, 1991, Volume: 40, Issue:1 Topics: Animals; Anticonvulsants; Bicuculline; Diazepam; Drug Interactions; Electroshock; Felbamate; GABA-A Receptor Antagonists; Isoniazid; Male; Mice; Pentylenetetrazole; Phenylcarbamates; Propylene Glycols; Seizures	1991
Stress-induced changes of central GABAergic function in rats. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1991, Volume: 12, Issue:5 Topics: Adrenalectomy; Animals; Blood Pressure; Diazepam; Down-Regulation; gamma-Aminobutyric Acid; Heart Rate; Hydrocortisone; Injections, Intraventricular; Isoniazid; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Restraint, Physical; Stress, Psychological	1991
In vivo administration of ethanol enhances the function of the gamma-aminobutyric acid-dependent chloride channel in the rat cerebral cortex. Journal of neurochemistry, 1990, Volume: 54, Issue:2 Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlorides; Diazepam; Ethanol; gamma-Aminobutyric Acid; Ion Channels; Isoniazid; Male; Rats; Rats, Inbred Strains	1990
Ex vivo binding of t-[35S )butylbicyclophosphorothionate: a biochemical tool to study the pharmacology of ethanol at the gamma-aminobutyric acid-coupled chloride channel. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:3 Topics: Animals; Azides; Benzodiazepines; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Convulsants; Diazepam; Drug Interactions; Ethanol; gamma-Aminobutyric Acid; Ion Channels; Isoniazid; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sulfur Radioisotopes	1991
Failure of gamma-hydroxybutyrate to alter the function of the GABAA receptor complex in the rat cerebral cortex. Psychopharmacology, 1991, Volume: 104, Issue:3 Topics: Animals; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlorides; Diazepam; Flunitrazepam; In Vitro Techniques; Ion Channels; Isoniazid; Male; Nerve Tissue Proteins; Rats; Rats, Inbred Strains; Receptors, GABA-A; Sodium Oxybate; Synaptic Transmission	1991
"Ex vivo" binding of 35S-TBPS as a tool to study the pharmacology of GABAA receptors. Advances in biochemical psychopharmacology, 1990, Volume: 46 Topics: Alprazolam; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Convulsants; Diazepam; Drug Synergism; Ethanol; In Vitro Techniques; Isoniazid; Male; Protein Conformation; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stress, Physiological; Sulfur Radioisotopes; Valproic Acid	1990
Isoniazid, an inhibitor of GABAergic transmission, enhances [35S]TBPS binding in rat cerebral cortex. European journal of pharmacology, 1989, May-19, Volume: 164, Issue:2 Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Cerebral Cortex; Convulsants; Diazepam; gamma-Aminobutyric Acid; Isoniazid; Male; Membranes; Rats; Rats, Inbred Strains; Sulfur Radioisotopes; Synaptic Transmission	1989
Synergistic anticonvulsant action of diazepam & clonazepam with amino-oxyacetic acid against isoniazid-induced convulsions in rats. The Indian journal of medical research, 1989, Volume: 90 Topics: Acetates; Aminooxyacetic Acid; Animals; Clonazepam; Diazepam; Drug Therapy, Combination; Isoniazid; Male; Rats; Rats, Inbred Strains; Seizures	1989
Possible inhibitory role of endogenous gamma-aminobutyric acid in the nonnicotinic functions of the dog cardiac sympathetic ganglia. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 233, Issue:3 Topics: 3-Mercaptopropionic Acid; Acetylcholine; Aminooxyacetic Acid; Angiotensin II; Animals; Bethanechol; Bethanechol Compounds; Diazepam; Dogs; Dose-Response Relationship, Drug; Female; gamma-Aminobutyric Acid; Ganglia, Sympathetic; Heart; Isoniazid; Male; Receptors, GABA-A	1985
2-Amino-6-trifluoromethoxy benzothiazole, a possible antagonist of excitatory amino acid neurotransmission--II. Biochemical properties. Neuropharmacology, 1985, Volume: 24, Issue:11 Topics: Acetylcholine; Amino Acids; Animals; Anticonvulsants; Apomorphine; Cerebellum; Chlordiazepoxide; Cyclic GMP; Diazepam; gamma-Aminobutyric Acid; Harmaline; In Vitro Techniques; Injections, Intraventricular; Isoniazid; Male; Rats; Rats, Inbred Strains; Riluzole; Synaptic Transmission; Thiazoles	1985
Emergency department management of children with acute isoniazid poisoning. Pediatric emergency care, 1986, Volume: 2, Issue:2 Topics: Adolescent; Child; Diazepam; Emergencies; Epilepsies, Partial; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Isoniazid; Male; Phenobarbital; Suicide, Attempted	1986
Microgram doses of diazepam do not induce proconvulsant or proconflict effects in rodents. Psychopharmacology, 1987, Volume: 93, Issue:3 Topics: Animals; Bicuculline; Conditioning, Operant; Diazepam; Isoniazid; Mice; Pentylenetetrazole; Picrotoxin; Punishment; Seizures	1987
[Analysis of the depressant effect of diazepam on the amplitude of phrenic nerve discharge in rabbits]. Sheng li xue bao : [Acta physiologica Sinica], 1985, Volume: 37, Issue:2 Topics: Action Potentials; Animals; Blood Pressure; Cyproheptadine; Depression, Chemical; Diazepam; gamma-Aminobutyric Acid; Isoniazid; Naloxone; Phrenic Nerve; Picrotoxin; Rabbits	1985
The specific protective effect of diazepam and valproate against isoniazid-induced seizures is not correlated with increased GABA levels. Journal of neural transmission, 1985, Volume: 63, Issue:2 Topics: Amino Acids; Animals; Diazepam; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Isoniazid; Male; Mice; Mice, Inbred Strains; Seizures; Time Factors; Valproic Acid	1985
Proceedings: Drug interaction on driving skills as evaluated by laboratory tests and by a driving simulator. Pharmakopsychiatrie, Neuro-Psychopharmakologie, 1973, Volume: 6, Issue:2 Topics: Adult; Attention; Automobile Driving; Chlordiazepoxide; Diazepam; Drug Interactions; Ethanol; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Isoniazid; Kinetics; Male; Motor Skills; Parasympatholytics; Reaction Time; Receptors, Drug; Task Performance and Analysis; Time Factors; Tranquilizing Agents	1973
Psychiatric side effects of nonpsychiatric drugs. Seminars in psychiatry, 1971, Volume: 3, Issue:4 Topics: Aminophylline; Analgesics; Anti-Anxiety Agents; Anti-Bacterial Agents; Anticonvulsants; Antiemetics; Antihypertensive Agents; Central Nervous System Stimulants; Chlordiazepoxide; Diazepam; Diuretics; Drug-Related Side Effects and Adverse Reactions; Furosemide; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Insulin; Isoniazid; Mental Disorders; Methyldopa; Phenobarbital; Prednisone	1971
Metabolism of diphenylhydantoin by rat liver microsomes. I. characteristics of the reaction. Biochemical pharmacology, 1970, Volume: 19, Issue:3 Topics: Adenosine Triphosphate; Animals; Azides; Biotransformation; Chlordiazepoxide; Chlorpromazine; Dextropropoxyphene; Diazepam; Diethylstilbestrol; Dimenhydrinate; Disulfiram; Hydantoins; Hydrogen-Ion Concentration; In Vitro Techniques; Isoniazid; Kinetics; Male; Methylene Blue; Microsomes, Liver; NAD; NADP; Oxygen; Phenobarbital; Phenytoin; Proadifen; Prochlorperazine; Rats; Sodium; Temperature	1970
Effect of diazepam on -aminobutyric acid (GABA) content of mouse brain. The Journal of pharmacy and pharmacology, 1972, Volume: 24, Issue:10 Topics: Aminobutyrates; Animals; Brain Chemistry; Diazepam; Injections, Intraperitoneal; Isoniazid; Male; Mice	1972
[Biologic availability as a function of the pharmaceutic form]. Bollettino chimico farmaceutico, 1974, Volume: 113, Issue:8 Topics: Animals; Biological Availability; Biopharmaceutics; Capsules; Diazepam; Dosage Forms; Ethambutol; Isoniazid; Rabbits; Tablets	1974
[Study of the conditions of absorption of determined drugs in various pharmaceutical oral forms]. Bollettino chimico farmaceutico, 1973, Volume: 112, Issue:2 Topics: Administration, Oral; Capsules; Chlordiazepoxide; Diazepam; Dosage Forms; Ethambutol; Intestinal Absorption; Isoniazid; Oxazepam; Pharmaceutical Preparations; Solutions; Tablets	1973
Interaction of alcohol and drugs on psychomotor skills as demonstrated by a driving simulator. British journal of pharmacology, 1973, Volume: 47, Issue:3 Topics: Adult; Automobile Driving; Codeine; Diazepam; Drug Interactions; Drug Synergism; Ethanol; Humans; Isoniazid; Male; Models, Theoretical; Motor Skills	1973
Isoniazid toxicity. Reversal with pyridoxine. Minnesota medicine, 1974, Volume: 57, Issue:2 Topics: Adolescent; Diazepam; Humans; Hyperglycemia; Hypothermia; Isoniazid; Lactates; Male; Pyridoxine; Seizures	1974
A disintegration test for evaluation of drug availability from tablets and capsules. Acta pharmaceutica Suecica, 1970, Volume: 7, Issue:5 Topics: Biopharmaceutics; Capsules; Chloramphenicol; Diazepam; Hardness Tests; Indomethacin; Isoniazid; Meprobamate; Solubility; Sulfamethizole; Tablets; Tetracycline	1970
Association of beta hydroxybutyric acidosis with isoniazid intoxication. Journal of toxicology. Clinical toxicology, 1984, Volume: 22, Issue:2 Topics: 3-Hydroxybutyric Acid; Acidosis; Adult; Bicarbonates; Diazepam; Female; Humans; Hydroxybutyrates; Isoniazid; Male; Pyridoxine; Renal Dialysis; Sodium Bicarbonate	1984
Decreased convulsant potency of picrotoxin and pentetrazol and enhanced [3H]flunitrazepam cortical binding following stressful manipulations in rats. Brain research, 1980, May-12, Volume: 189, Issue:2 Topics: Animals; Anti-Anxiety Agents; Cerebral Cortex; Diazepam; Flunitrazepam; GABA Antagonists; gamma-Aminobutyric Acid; Isoniazid; Male; Muscimol; Pentylenetetrazole; Picrotoxin; Rats; Seizures; Stress, Physiological; Thiosemicarbazones	1980
[Use of the Soviet tranquilizer, phenazepam, for the prevention and treatment of the "acute" toxicity of isoniazid]. Problemy tuberkuleza, 1980, Issue:4 Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Diazepam; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Isoniazid; Lethal Dose 50; Male; Mice; Mice, Inbred CBA; Rats; Time Factors; USSR	1980
A probable site of action of diazepam in rat cerebellar GABA system. Life sciences, 1980, Nov-10, Volume: 27, Issue:19 Topics: Amphetamine; Animals; Cerebellum; Cyclic GMP; Diazepam; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Isoniazid; Kinetics; Male; Oxotremorine; Rats	1980
Anticonvulsant effects of caerulein, cholecystokinin octapeptide (CCK-8) and diazepam against seizures produced in mice by harman, thiosemicarbazide and isoniazid. Neuroscience letters, 1981, Jul-02, Volume: 24, Issue:2 Topics: Animals; Anticonvulsants; Ceruletide; Cholecystokinin; Diazepam; Haloperidol; Harmine; Isoniazid; Male; Mice; Mice, Inbred Strains; Seizures; Semicarbazides; Sincalide	1981
Contrasting effects of ethyl beta-carboline-3-carboxylate (beta CCE) and diazepam on cerebellar cyclic GMP content and antagonism of both effects by Ro 15-1788, a specific benzodiazepine receptor blocker. European journal of pharmacology, 1983, May-20, Volume: 90, Issue:1 Topics: Animals; Benzodiazepinones; Carbolines; Cerebellum; Cyclic GMP; Diazepam; Flumazenil; In Vitro Techniques; Indoles; Isoniazid; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A	1983
Increase in the Bmax of gamma-aminobutyric acid-A recognition sites in brain regions of mice receiving diazepam. Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:7 Topics: Animals; Brain; Cerebellum; Diazepam; gamma-Aminobutyric Acid; Isoniazid; Kinetics; Mice; Motor Activity; Muscimol; Organ Specificity; Rats; Receptors, Cell Surface; Receptors, GABA-A; Seizures	1984
Isoniazid poisoning in a dog. The Veterinary record, 1982, Nov-13, Volume: 111, Issue:20 Topics: Animals; Diazepam; Dog Diseases; Dogs; Fluid Therapy; Isoniazid; Male; Pentobarbital; Seizures	1982
Diazepam interaction with antituberculosis drugs. Clinical pharmacology and therapeutics, 1981, Volume: 29, Issue:5 Topics: Adult; Antitubercular Agents; Blood Proteins; Diazepam; Drug Interactions; Ethambutol; Female; Humans; Isoniazid; Kinetics; Male; Protein Binding; Rifampin	1981
Diphenylhydantoin potentiates the protective effect of diazepam against pentylenetetrazol but not against bicuculline and isoniazid-induced seizures in mice. Neuropharmacology, 1981, Volume: 20, Issue:7 Topics: Animals; Bicuculline; Diazepam; Drug Synergism; Isoniazid; Male; Mice; Pentylenetetrazole; Phenytoin; Seizures	1981
Effect of L-glutamine and isoniazid on torticollis and segmental dystonia. Annals of neurology, 1981, Volume: 10, Issue:3 Topics: Adult; Diazepam; Drug Therapy, Combination; Dystonia; Glutamine; Humans; Isoniazid; Middle Aged; Pyridoxine; Torticollis	1981
Acute isoniazid poisoning in children. Indian pediatrics, 1981, Volume: 18, Issue:11 Topics: Acute Disease; Child, Preschool; Coma; Diazepam; Female; Humans; Isoniazid; Pyridoxine; Seizures	1981
Isoniazid-associated rhabdomyolysis. The American journal of emergency medicine, 1995, Volume: 13, Issue:5 Topics: Adolescent; Charcoal; Chemical and Drug Induced Liver Injury; Diazepam; Female; Humans; Isoniazid; Pyridoxine; Rhabdomyolysis; Seizures	1995
Repeated treatment with alpidem, a new anxiolytic, does not induce tolerance or physical dependence. Neuropharmacology, 1993, Volume: 32, Issue:9 Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Bicuculline; Carbolines; Convulsants; Diazepam; Drug Tolerance; Flumazenil; Imidazoles; Isoniazid; Male; Mice; Pentylenetetrazole; Pyridines; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders	1993
Anticonvulsant doses of 2-chloro-N6-cyclopentyladenosine, an adenosine A1 receptor agonist, reduce GABAergic transmission in different areas of the mouse brain. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:2 Topics: Adenosine; Animals; Anticonvulsants; Behavior, Animal; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Convulsants; Depression, Chemical; Diazepam; Dose-Response Relationship, Drug; Flunitrazepam; gamma-Aminobutyric Acid; Isoniazid; Male; Mice; Mice, Inbred Strains; Purinergic P1 Receptor Antagonists; Receptors, GABA; Receptors, Purinergic P1; Seizures; Sulfur Radioisotopes; Synaptic Transmission; Tritium; Xanthines	1993
Antagonism of isoniazid-induced convulsions by abecarnil in mice tolerant to diazepam. Pharmacology, biochemistry, and behavior, 1995, Volume: 52, Issue:2 Topics: Animals; Anticonvulsants; Benzodiazepines; Carbolines; Convulsants; Diazepam; Dose-Response Relationship, Drug; Drug Tolerance; GABA Modulators; Imidazoles; Isoniazid; Male; Mice; Seizures	1995
Antagonism of convulsions but failure to enhance GABA(A) receptor function by felbamate in mice tolerant to diazepam. Neurochemical research, 1997, Volume: 22, Issue:6 Topics: Animals; Anticonvulsants; Diazepam; Down-Regulation; Drug Evaluation, Preclinical; Drug Tolerance; Excitatory Amino Acid Antagonists; Felbamate; GABA Modulators; Isoniazid; Kynurenic Acid; Male; Mice; Phenylcarbamates; Propylene Glycols; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Time Factors	1997
Sarmazenil-precipitated withdrawal: a reliable method for assessing dependence liability of benzodiazepine receptor ligands. Pharmacology, biochemistry, and behavior, 1998, Volume: 59, Issue:4 Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Benzodiazepines; Convulsants; Diazepam; Drug Tolerance; Female; GABA-A Receptor Agonists; Imidazoles; Isoniazid; Ligands; Mice; Mice, Inbred Strains; Pentylenetetrazole; Rats; Rats, Inbred Strains; Saimiri; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders	1998
Pharmacological studies on synthetic flavonoids: comparison with diazepam. Neuropharmacology, 1999, Volume: 38, Issue:7 Topics: Animals; Anti-Anxiety Agents; Avoidance Learning; Diazepam; Discrimination Learning; Escape Reaction; Flavonoids; Isoniazid; Light; Male; Maze Learning; Motor Activity; Punishment; Rats; Rats, Wistar; Receptors, GABA-A; Risk Assessment; Seizures	1999
The effect of a novel pentadecapeptide BPC 157 on development of tolerance and physical dependence following repeated administration of diazepam. The Chinese journal of physiology, 1999, Sep-30, Volume: 42, Issue:3 Topics: Amino Acid Sequence; Animals; Anti-Ulcer Agents; Anticonvulsants; Antitubercular Agents; Brain Chemistry; Diazepam; Drug Interactions; Drug Tolerance; Epilepsy; Isoniazid; Male; Mice; Mice, Inbred Strains; Molecular Sequence Data; Peptide Fragments; Picrotoxin; Proteins; Receptors, GABA-A; Substance Withdrawal Syndrome	1999
Differential role of dopamine D1 and D2 receptors in isoniazid-induced vacuous chewing movements. Methods and findings in experimental and clinical pharmacology, 2000, Volume: 22, Issue:10 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Anticonvulsants; Antipsychotic Agents; Antitubercular Agents; Behavior, Animal; Diazepam; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; gamma-Aminobutyric Acid; Isoniazid; Male; Mastication; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Stereotyped Behavior; Time Factors	2000
[Effects of rifampin and isoniazid on the pharmacokinetics of diazepam in rabbits]. Yao xue xue bao = Acta pharmaceutica Sinica, 1997, Volume: 32, Issue:7 Topics: Animals; Cytochrome P-450 Enzyme System; Diazepam; Isoniazid; Male; Microsomes, Liver; Rabbits; Random Allocation; Rifampin	1997
Do not overlook acute isoniazid poisoning in children with status epilepticus. Journal of child neurology, 2003, Volume: 18, Issue:2 Topics: Acidosis; Antitubercular Agents; Child, Preschool; Diagnosis, Differential; Diazepam; Drug Overdose; Electroencephalography; Female; Humans; Isoniazid; Pyridoxine; Status Epilepticus; Treatment Outcome	2003
Acute effect of an extract of Ambrosia paniculata (Willd.) O. E. Schultz (mugwort) in several models of experimental epilepsy. Epilepsy & behavior : E&B, 2004, Volume: 5, Issue:6 Topics: Ambrosia; Analysis of Variance; Animals; Anticonvulsants; Behavior, Animal; Cerebral Cortex; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography; Electroshock; Epilepsy; Exploratory Behavior; Isoniazid; Male; Mice; Motor Activity; Penicillins; Phytotherapy; Picrotoxin; Plant Preparations; Psychomotor Performance; Rats; Reaction Time; Time Factors; Tubocurarine	2004
Low tolerance and dependence liabilities of etizolam: molecular, functional, and pharmacological correlates. European journal of pharmacology, 2005, Sep-05, Volume: 519, Issue:1-2 Topics: Animals; Animals, Newborn; Binding, Competitive; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Cerebral Cortex; Diazepam; Fluorescent Antibody Technique; GABA Modulators; Gene Expression; Hippocampus; Isoniazid; Lorazepam; Male; Membrane Potentials; Mice; Neurons; Patch-Clamp Techniques; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; RNA, Messenger; Seizures; Sulfur Radioisotopes; Tranquilizing Agents	2005
Seizures, metabolic acidosis and coma resulting from acute isoniazid intoxication. Anaesthesia and intensive care, 2005, Volume: 33, Issue:4 Topics: Acidosis; Acute Disease; Adolescent; Anticonvulsants; Antitubercular Agents; Charcoal; Child; Coma; Diazepam; Female; Gastric Lavage; Humans; Intubation, Intratracheal; Isoniazid; Pyridoxine; Seizures; Sodium Bicarbonate; Suicide, Attempted; Thiopental; Vitamin B Complex	2005
[Isoniazid intoxication]. Deutsche medizinische Wochenschrift (1946), 2007, Jan-05, Volume: 132, Issue:1-2 Topics: Acidosis; Anticonvulsants; Antidotes; Antitubercular Agents; Diazepam; Female; Humans; Infusions, Intravenous; Isoniazid; Middle Aged; Pyridoxine; Recurrence; Seizures; Suicide, Attempted; Vitamin B Complex	2007
Validation of anticonvulsant and sedative activity of six medicinal plants. Epilepsy & behavior : E&B, 2009, Volume: 14, Issue:3 Topics: Animals; Anticonvulsants; Convulsants; Diazepam; Dose-Response Relationship, Drug; Electroshock; Epilepsy; Excitatory Amino Acid Agonists; Hypnotics and Sedatives; Isoniazid; Male; Medicine, African Traditional; Mice; N-Methylaspartate; Pentylenetetrazole; Picrotoxin; Plants, Medicinal; Sleep Initiation and Maintenance Disorders; Stereotyped Behavior; Strychnine	2009
Antiepileptic potential of ursolic acid stearoyl glucoside by GABA receptor stimulation. CNS neuroscience & therapeutics, 2012, Volume: 18, Issue:9 Topics: Animals; Anticonvulsants; Convulsants; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Epilepsy; Glucosides; Isoniazid; Lantana; Phytotherapy; Plant Extracts; Plant Leaves; Receptors, GABA; Saponins; Seizures; Triterpenes; Ursolic Acid	2012
Oral pyridoxine can substitute for intravenous pyridoxine in managing patients with severe poisoning with isoniazid and rifampicin fixed dose combination tablets: a case report. BMC research notes, 2017, Aug-08, Volume: 10, Issue:1 Topics: Administration, Oral; Antidotes; Antitubercular Agents; Diazepam; Drug Combinations; Female; Humans; Isoniazid; Pyridoxine; Rifampin; Seizures; Sri Lanka; Suicide, Attempted; Tablets; Treatment Outcome; Unconsciousness; Young Adult	2017
Biochemical and functional identification of GABA receptors in Hydra vulgaris. Life sciences, 1995, Volume: 56, Issue:18 Topics: Animals; Baclofen; Bicuculline; Binding, Competitive; Diazepam; Feeding Behavior; gamma-Aminobutyric Acid; Glutathione; Hydra; Kinetics; Membranes; Receptors, GABA; Sensitivity and Specificity; Stimulation, Chemical; Tritium	1995
Modulation of gamma-aminobutyric acid (GABA) receptors and the feeding response by neurosteroids in Hydra vulgaris. Neuroscience, 1998, Volume: 85, Issue:3 Topics: Anesthetics; Animals; Anti-Anxiety Agents; Bicuculline; Carbolines; Cerebral Cortex; Chemoreceptor Cells; Clonazepam; Desoxycorticosterone; Diazepam; Feeding Behavior; GABA Antagonists; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Glutathione; Hydra; Neurotransmitter Agents; Pregnanolone; Progesterone; Pyridazines; Radioligand Assay; Rats; Receptors, GABA-A; Tritium	1998
Diazepam-binding inhibitor-like activity in rat cerebrospinal fluid after stimulation by an aversive quinine taste. Chemical senses, 2000, Volume: 25, Issue:6 Topics: Animals; Cerebrospinal Fluid; Diazepam; Drinking; Flumazenil; GABA-A Receptor Antagonists; Glutathione; Hydra; Male; Mice; Peptide Fragments; Pronase; Quinine; Rats; Rats, Wistar; Sucrose; Taste	2000