diazepam has been researched along with isomethyleugenol in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (63.64) | 18.7374 |
| 1990's | 4 (18.18) | 18.2507 |
| 2000's | 1 (4.55) | 29.6817 |
| 2010's | 3 (13.64) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beyer, KH; Hilderbrandt, AG; Sadée, W; Schwandt, HJ | 1 |
| Beischlag, TV; Inaba, T; Kalow, W; Mahon, WA | 1 |
| Bruce, I; Hooper, WD; Reilly, PE | 1 |
| Benistant, C; Fonlupt, P; Rey, C | 1 |
| Gill, MW; Schatz, RA | 1 |
| Hailey, DM | 1 |
| Iisalo, E; Kanto, J; Lehtinen, V; Salminen, J | 1 |
| Fanelli, R; Garattini, S; Marcucci, F; Mussini, E | 3 |
| Bertagni, P; Garattini, S; Marcucci, F; Mussini, E | 1 |
| Garattini, S; Guaitani, A; Marcucci, F | 1 |
| Fanelli, R; Garattini, S; Guaitani, A; Marcucci, F; Mussini, E | 1 |
| Battistella, A; Calderini, G; Di Perri, B; Raciti, R; Toffano, G | 1 |
| Battistella, A; Di Perri, B; Raciti, R; Rosselli, P; Toffano, G | 1 |
| Kojima, M; Maeda, M; Uozumi, F | 1 |
| Ariyoshi, Y; Iio, M; Kojima, M; Maeda, M; Suehiro, M | 1 |
| Funae, Y; Imaoka, S; Kamataki, T; Neville, CF; Ninomiya, S; Shimada, N | 1 |
| Chebib, M; Davucheron, NL; Hall, BJ; Hanrahan, JR; Johnston, GA | 1 |
| Denman, RB; Merz, G; Sung, YJ; Xie, W | 1 |
| Araujo Cordeiro, KC; Costa, MB; da Silva e Sousa, DB; de Melo Souza, PL; de Oliveira, V; de Paula, NC; Noël, F; Nogueira, DF | 1 |
| Jin, J; Kosowan, J; Leung, L; Li, YX; Oh, G; Petronis, A; Samsom, J; Wang, DY; Wong, AHC; Xiong, Y; Zhang, KL | 1 |
1 review(s) available for diazepam and isomethyleugenol
| Article | Year |
|---|---|
Chromatography of the 1,4-benzodiazepines.
Topics: Anti-Anxiety Agents; Chlordiazepoxide; Chromatography; Diazepam; Flurazepam; Humans; Methylation; Nitrazepam; Oxazepam; Oxazoles; Prazepam; Solvents; Spectrometry, Fluorescence; Temperature | 1974 |
21 other study(ies) available for diazepam and isomethyleugenol
| Article | Year |
|---|---|
Effects of enzyme induction and inhibition on microsomal oxidation of 1,4-benzodiazepines.
Topics: Animals; Anti-Anxiety Agents; Cytochrome P-450 Enzyme System; Dealkylation; Diazepam; Hydroxylation; Male; Medazepam; Methylation; Metyrapone; Microsomes, Liver; Phenobarbital; Rats | 1976 |
Diazepam metabolism by rat and human liver in vitro: inhibition by mephenytoin.
Topics: Animals; Chromatography, Gas; Diazepam; Humans; Hydroxylation; In Vitro Techniques; Kinetics; Liver; Male; Mephenytoin; Methylation; Nordazepam; Polymorphism, Genetic; Rats; Temazepam | 1992 |
Comparative metabolism of clinically important precursors of N-desmethyldiazepam using phenobarbitone-pretreated rat liver microsomes.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Diazepam; Hydroxylation; Male; Methylation; Microsomes, Liver; Nordazepam; Phenobarbital; Prazepam; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1992 |
Increase of GABA-stimulated diazepam binding after lipid methylation in membrane preparations from rat brain.
Topics: Animals; Brain; Diazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Lipids; Methylation; Phospholipids; Rats; Rats, Inbred Strains; Receptors, GABA-A; S-Adenosylmethionine | 1990 |
The effect of diazepam on brain levels of S-adenosyl-L-methionine and S-adenosyl-L-homocysteine: possible correlation with protection from methionine sulfoximine seizures.
Topics: Animals; Brain Chemistry; Diazepam; Dose-Response Relationship, Drug; Homocysteine; Male; Methionine Sulfoximine; Methylation; Mice; Reaction Time; S-Adenosylhomocysteine; S-Adenosylmethionine; Seizures | 1985 |
The concentrations of diazepam and its metabolites in the plasma after an acute and chronic administration.
Topics: Anxiety Disorders; Chromatography, Gas; Diazepam; Humans; Methylation; Microsomes, Liver; Oxazepam; Substance-Related Disorders; Time Factors | 1974 |
Metabolism of diazepam metabolites in guinea pigs.
Topics: Adipose Tissue; Animals; Brain; Chromatography, Gas; Diazepam; Guinea Pigs; Kinetics; Male; Methylation; Oxazepam | 1972 |
Biliary excretion of conjugated hydroxyl benzodiazepines after administration of several benzodiazepines to rats, guinea pigs, and mice.
Topics: Animals; Bile; Biotransformation; Dealkylation; Diazepam; Guinea Pigs; Half-Life; Hydrolysis; Hydroxylation; Injections, Intravenous; Male; Methylation; Mice; Oxazepam; Rats; Species Specificity | 1972 |
Increased aggression and toxicity in grouped male mice treated with tranquilizing benzodiazepines.
Topics: Aggression; Animals; Behavior, Animal; Diazepam; Dibenzazepines; Female; Humans; Male; Methylation; Necrosis; Oxazepam; Sex Factors; Social Isolation; Tranquilizing Agents; Wounds and Injuries | 1971 |
Metabolism and anticonvulsant activity of diazepam in guinea pigs.
Topics: Adipose Tissue; Animals; Anticonvulsants; Brain; Chromatography, Gas; Diazepam; Drug Antagonism; Guinea Pigs; Kinetics; Male; Methylation; Oxazepam; Pentylenetetrazole; Seizures; Time Factors; Tremor | 1971 |
Metabolism of diazepam and its metabolites by guinea pig liver microsomes.
Topics: Animals; Diazepam; Guinea Pigs; In Vitro Techniques; Male; Methylation; Microsomes, Liver; Oxazepam | 1971 |
Effect of phenobarbital on the in vitro metabolism of diazepam in several animal species.
Topics: Animals; Chromatography, Gas; Dealkylation; Diazepam; Fasting; Guinea Pigs; Male; Metabolism; Methylation; Mice; Microsomes, Liver; Mixed Function Oxygenases; Oxazepam; Phenobarbital; Rats; Species Specificity | 1970 |
Phospholipid methylation increases [3H]diazepam and [3H]GABA binding in membrane preparations of rat cerebellum.
Topics: Animals; Cerebellum; Diazepam; gamma-Aminobutyric Acid; Kinetics; Methylation; Phospholipids; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; S-Adenosylmethionine; Synaptic Membranes | 1983 |
Molecular mechanisms in the antiepileptic action of benzodiazepines.
Topics: Animals; Anticonvulsants; Benzodiazepines; Biomechanical Phenomena; Cell Membrane; Cerebellum; Diazepam; gamma-Aminobutyric Acid; Lipids; Methylation; Phospholipids; Rats; Receptors, Cell Surface; Receptors, GABA-A; S-Adenosylmethionine; Synapses | 1983 |
Synthesis of [N-methyl-3H]-7-chloro-1,3-dihydro-5-(2-fluorophenyl)-1-methyl-2 H-1,4-benzodiazepin-2- one (3H-fludiazepam) by phase transfer catalysis.
Topics: Anti-Anxiety Agents; Benzodiazepines; Catalysis; Diazepam; Hydrocarbons, Iodinated; Isotope Labeling; Methylation; Tritium | 1984 |
Carbon-11 labeling of fludiazepam.
Topics: Acetone; Anti-Anxiety Agents; Benzodiazepines; Carbon Radioisotopes; Diazepam; Hydrocarbons, Iodinated; Isotope Labeling; Methylation | 1982 |
Characterization of specific cytochrome P450 enzymes responsible for the metabolism of diazepam in hepatic microsomes of adult male rats.
Topics: Animals; Cytochrome P-450 Enzyme System; Diazepam; Hydroxylation; Immune Sera; Isoenzymes; Male; Methylation; Microsomes, Liver; Rats; Rats, Wistar | 1993 |
Semisynthetic preparation of amentoflavone: A negative modulator at GABA(A) receptors.
Topics: Animals; Biflavonoids; Diazepam; Flowers; Flumazenil; GABA Antagonists; GABA Modulators; Ginkgo biloba; Humans; Hypericum; Magnetic Resonance Spectroscopy; Methylation; Oocytes; Patch-Clamp Techniques; Plant Leaves; Receptors, GABA-A; Recombinant Proteins; Xenopus laevis | 2003 |
GABAAergic stimulation modulates intracellular protein arginine methylation.
Topics: Animals; Arginine; Bicuculline; Cell Differentiation; Cell Line; Diazepam; Drug Synergism; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Intracellular Space; Methylation; Mice, Knockout; Muscimol; Neurons; Protein-Arginine N-Methyltransferases; Receptors, GABA-A; Signal Transduction | 2014 |
Biosynthesis of human diazepam and clonazepam metabolites.
Topics: Anticonvulsants; Beauveria; Chaetomium; Clonazepam; Cunninghamella; Diazepam; Fungi; Humans; Hydrolysis; Hydroxylation; Industrial Microbiology; Methylation; Rhizopus | 2015 |
Inhibition of the G9a/GLP histone methyltransferase complex modulates anxiety-related behavior in mice.
Topics: Animals; Anti-Anxiety Agents; Diazepam; Dose-Response Relationship, Drug; Epigenesis, Genetic; Female; Histone-Lysine N-Methyltransferase; Histones; Indoles; Male; Methylation; Mice, Inbred C57BL; Protein Processing, Post-Translational; Quinazolines; Spiro Compounds; Venlafaxine Hydrochloride | 2018 |