diazepam and ipsapirone

diazepam has been researched along with ipsapirone in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.00)18.7374
1990's23 (92.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Marsden, CA; Upton, N; Wright, IK1
Fernández-Guasti, A; Hong, E; López-Rubalcava, C1
Heaton, M; Marsden, CA; Upton, N; Wright, IK1
Costall, B; Domeney, AM; Farre, AJ; Kelly, ME; Martinez, L; Naylor, RJ1
Almeida, SS; de Oliveira, LM; Graeff, FG2
Kaltwasser, MT1
Inoue, Y; Ohno, M; Shibata, S; Teshima, K; Tominaga, K; Ueki, S; Ushio, M; Watanabe, S; Yamamoto, T1
Budziszewska, B; Grochmal, A; Przegaliński, E1
Fernández-Guasti, A; López-Rubalcava, C2
Bohus, B; Koolhaas, JM; Korte, SM; Schuurman, T; Traber, J1
Albrecht, JW; Borison, RL; Diamond, BI1
Fernández-Guasti, A; Picazo, O1
Caruso, J; Molino, LJ; Shemer, AV; Whitaker-Azmitia, PM1
Peroutka, SJ1
Davies, MA; Dompert, WU; Glaser, T; Schuurman, T; Seidel, PR; Traber, J1
Graeff, FG; Tomaz, C; Viana, MB1
Boyer, WF; Feighner, JP1
Hong, E; Meneses, A1
Cutler, NR; Hesselink, JM; Sramek, JJ1
Sánchez, C1
Cervo, L; Samanin, R1
Fijał, K; Gołembiowska, K; Maćkowiak, M; Wedzony, K1
Dourish, CT; Stanhope, KJ1

Trials

3 trial(s) available for diazepam and ipsapirone

ArticleYear
Efficacy and safety of a putative anxiolytic agent: ipsapirone.
    Psychopharmacology bulletin, 1990, Volume: 26, Issue:2

    Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Double-Blind Method; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Pyrimidines

1990
A placebo-controlled double-blind multicenter trial of two doses of ipsapirone versus diazepam in generalized anxiety disorder.
    International clinical psychopharmacology, 1993,Fall, Volume: 8, Issue:3

    Topics: Ambulatory Care; Analysis of Variance; Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Double-Blind Method; Humans; Psychological Tests; Pyrimidines; Serotonin Receptor Agonists

1993
A phase II multicenter dose-finding, efficacy and safety trial of ipsapirone in outpatients with generalized anxiety disorder.
    Progress in neuro-psychopharmacology & biological psychiatry, 1994, Volume: 18, Issue:3

    Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Diazepam; Double-Blind Method; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Pyrimidines

1994

Other Studies

22 other study(ies) available for diazepam and ipsapirone

ArticleYear
Effect of established and putative anxiolytics on extracellular 5-HT and 5-HIAA in the ventral hippocampus of rats during behaviour on the elevated X-maze.
    Psychopharmacology, 1992, Volume: 109, Issue:3

    Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Behavior, Animal; Diazepam; Hippocampus; Hydroxyindoleacetic Acid; Male; Microdialysis; Pyridazines; Pyrimidines; Rats; Serotonin

1992
Species differences in the mechanism through which the serotonergic agonists indorenate and ipsapirone produce their anxiolytic action.
    Psychopharmacology, 1992, Volume: 107, Issue:1

    Topics: 5-Methoxytryptamine; Alprenolol; Analysis of Variance; Animals; Anti-Anxiety Agents; Behavior, Animal; Diazepam; Male; Methiothepin; Mice; Pindolol; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Species Specificity

1992
Comparison of acute and chronic treatment of various serotonergic agents with those of diazepam and idazoxan in the rat elevated X-maze.
    Psychopharmacology, 1992, Volume: 107, Issue:2-3

    Topics: Adrenergic alpha-Antagonists; Animals; Anti-Anxiety Agents; Diazepam; Dioxanes; Idazoxan; Imidazoles; Male; Ondansetron; Pyrimidines; Rats; Ritanserin; Serotonin; Serotonin Antagonists; Substance Withdrawal Syndrome

1992
Profile of action of a novel 5-hydroxytryptamine1A receptor ligand E-4424 to inhibit aversive behavior in the mouse, rat and marmoset.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 262, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Buspirone; Callithrix; Diazepam; Female; Guinea Pigs; Injections, Intraperitoneal; Male; Mice; Muscle Contraction; Muscle, Smooth; Piperazines; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Substance Withdrawal Syndrome

1992
Early life protein malnutrition changes exploration of the elevated plus-maze and reactivity to anxiolytics.
    Psychopharmacology, 1991, Volume: 103, Issue:4

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Diazepam; Dose-Response Relationship, Drug; Exploratory Behavior; Male; Piperidines; Propanolamines; Protein-Energy Malnutrition; Pyrimidines; Rats; Rats, Inbred Strains; Ritanserin

1991
Acoustic startle induced ultrasonic vocalization in the rat: a novel animal model of anxiety?
    Behavioural brain research, 1991, May-15, Volume: 43, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Appetite Depressants; Arousal; Carbolines; Diazepam; Disease Models, Animal; Electroshock; Fear; Flunitrazepam; Male; Maprotiline; Pyrimidines; Rats; Rats, Inbred Strains; Reflex, Startle; Ultrasonics; Vocalization, Animal

1991
[Behavioral pharmacological and electroencephalographic effects of the 5-HT1A partial agonist ipsapirone].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1991, Volume: 98, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Buspirone; Diazepam; Drug Synergism; Electroencephalography; Flumazenil; Male; Mice; Motor Activity; Pyrimidines; Rabbits; Rats; Rats, Inbred Strains; Serotonin

1991
Oxaprotiline enantiomers stimulate ACTH and corticosterone secretion in the rat.
    Journal of neural transmission. General section, 1991, Volume: 85, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Benzylamines; Corticosterone; Dexamethasone; Diazepam; Dose-Response Relationship, Drug; Male; Maprotiline; Metergoline; Naloxone; Piperidines; Pyrimidines; Radioimmunoassay; Rats; Rats, Inbred Strains; Serotonin Antagonists; Stereoisomerism; Sulpiride; Sympathomimetics

1991
Evidence for the involvement of the 5-HT1A receptor in the anxiolytic action of indorenate and ipsapirone.
    Psychopharmacology, 1990, Volume: 101, Issue:3

    Topics: 5-Methoxytryptamine; Alprenolol; Animals; Anti-Anxiety Agents; Antihypertensive Agents; Diazepam; Exploratory Behavior; Male; Methiothepin; Mice; Motor Activity; Pindolol; Pyrimidines; Receptors, Serotonin; Serotonin

1990
Anxiolytics and stress-induced behavioural and cardiac responses: a study of diazepam and ipsapirone (TVX Q 7821).
    European journal of pharmacology, 1990, Apr-25, Volume: 179, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Diazepam; Electrocardiography; Electroshock; Heart; Male; Pyrimidines; Rats; Rats, Inbred Strains; Stress, Psychological

1990
Decreased reactivity to anxiolytics caused by early protein malnutrition in rats.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 36, Issue:4

    Topics: Animals; Anti-Anxiety Agents; Body Weight; Diazepam; Diet; Dose-Response Relationship, Drug; Hypertonic Solutions; Lactation; Male; Piperidines; Propanolamines; Protein-Energy Malnutrition; Pyrimidines; Rats; Rats, Inbred Strains; Ritanserin

1990
The actions of diazepam and serotonergic anxiolytics vary according to the gender and the estrous cycle phase.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 37, Issue:1

    Topics: 5-Methoxytryptamine; Animals; Anti-Anxiety Agents; Behavior, Animal; Buspirone; Diazepam; Dose-Response Relationship, Drug; Female; Male; Metestrus; Proestrus; Pyrimidines; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Serotonin; Sex Factors

1990
Serotonergic agents restore appropriate decision-making in neonatal rats displaying dopamine D1 receptor-mediated vacillatory behavior.
    European journal of pharmacology, 1990, May-16, Volume: 180, Issue:2-3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Animals, Newborn; Behavior, Animal; Buspirone; Clomipramine; Decision Making; Diazepam; Female; Pregnancy; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Serotonin

1990
Selective interaction of novel anxiolytics with 5-hydroxytryptamine1A receptors.
    Biological psychiatry, 1985, Volume: 20, Issue:9

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Binding, Competitive; Brain; Buspirone; Cattle; Depression, Chemical; Diazepam; Flunitrazepam; In Vitro Techniques; Lorazepam; Pyrimidines; Receptors, Serotonin; Tetrahydronaphthalenes

1985
Brain serotonin receptors as a target for the putative anxiolytic TVX Q 7821.
    Brain research bulletin, 1984, Volume: 12, Issue:6

    Topics: Aggression; Analgesia; Animals; Avoidance Learning; Brain; Diazepam; Electroshock; Flunitrazepam; Humans; Male; Mice; Mice, Inbred Strains; Pyrimidines; Receptors, Serotonin; Serotonin

1984
The elevated T-maze: a new animal model of anxiety and memory.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 49, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Diazepam; Dose-Response Relationship, Drug; Male; Memory; Models, Psychological; Pyrimidines; Rats; Rats, Wistar

1994
Modification of the anxiolytic effects of 5-HT1A agonists by shock intensity.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 46, Issue:3

    Topics: 5-Methoxytryptamine; Animals; Anti-Anxiety Agents; Buspirone; Conditioning, Operant; Conflict, Psychological; Diazepam; Electroshock; Male; Pyrimidines; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Receptor Agonists

1993
Serotonergic mechanisms involved in the exploratory behaviour of mice in a fully automated two-compartment black and white text box.
    Pharmacology & toxicology, 1995, Volume: 77, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Animals; Anti-Anxiety Agents; Anxiety Disorders; Buspirone; Chlordiazepoxide; Darkness; Diazepam; Disease Models, Animal; Exploratory Behavior; Fenfluramine; Light; Male; Mice; Penbutolol; Propanolamines; Pyrimidines; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists

1995
Presynaptic 5-HT1A receptors mediate the effect of ipsapirone on punished responding in rats.
    European journal of pharmacology, 1995, Sep-25, Volume: 284, Issue:3

    Topics: 5,7-Dihydroxytryptamine; Animals; Anti-Anxiety Agents; Conditioning, Operant; Diazepam; Dose-Response Relationship, Drug; Male; Piperazines; Punishment; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Receptor Agonists

1995
Evidence that conditioned stress enhances outflow of dopamine in rat prefrontal cortex: a search for the influence of diazepam and 5-HT1A agonists.
    Synapse (New York, N.Y.), 1996, Volume: 24, Issue:3

    Topics: Animals; Anti-Anxiety Agents; Buspirone; Diazepam; Dopamine; Dose-Response Relationship, Drug; Fear; Male; Microdialysis; Prefrontal Cortex; Pyrimidines; Rats; Rats, Wistar; Serotonin Receptor Agonists; Stress, Psychological

1996
Effects of 5-HT1A receptor agonists, partial agonists and a silent antagonist on the performance of the conditioned emotional response test in the rat.
    Psychopharmacology, 1996, Volume: 128, Issue:3

    Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Behavior, Animal; Chlordiazepoxide; Conditioning, Operant; Diazepam; Electroshock; Food Deprivation; Male; Muscarinic Antagonists; Piperazines; Pyridines; Pyrimidines; Rats; Receptors, Serotonin; Scopolamine; Serotonin Agents; Serotonin Antagonists

1996
Modification of the anxiolytic action of 5-HT1A compounds by GABA-benzodiazepine agents in rats.
    Pharmacology, biochemistry, and behavior, 1998, Volume: 60, Issue:1

    Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Anxiety; Bicuculline; Buspirone; Diazepam; Drug Interactions; Flumazenil; GABA Agonists; Male; Psychomotor Performance; Pyrimidines; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1

1998