diazepam and ibuprofen

diazepam has been researched along with ibuprofen in 55 studies

Research

Studies (55)

TimeframeStudies, this research(%)All Research%
pre-19904 (7.27)18.7374
1990's11 (20.00)18.2507
2000's17 (30.91)29.6817
2010's21 (38.18)24.3611
2020's2 (3.64)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Duffy, EM; Jorgensen, WL1
Topliss, JG; Yoshida, F1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Chang, TK; Ensom, MH; Kiang, TK1
Caron, G; Ermondi, G1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Lombardo, F; Obach, RS; Waters, NJ1
Chuang, S; Horne, J; Porter, CJ; Scanlon, MJ; Velkov, T1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Avdeef, A; Tam, KY1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Buttar, D; Colclough, N; Gerhardt, S; MacFaul, PA; Maskos, K; Phillips, SD; Plowright, A; Steinbacher, S; Steuber, H; Tam, K; Whittamore, P1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Kaliszan, R; Noctor, TA; Pham, CD; Wainer, IW1
Cobbs, LW1
Hatakeyama, H; Hirose, K; Jyoyama, H; Matsubara, T; Otsubo, S; Touchi, A1
Bloss, JL; Hammond, DL1
Court, H; Streete, P; Volans, GN1
Ascoli, G; Bertucci, C; Salvadori, P1
Gear, RW; Gordon, NC; Heller, PH; Levine, JD; Miaskowski, C; Paul, SM1
Itoh, T; Saura, Y; Tsuda, Y; Yamada, H1
Gunaratna, C; Kissinger, PT1
Kosa, T; Maruyama, T; Otagiri, M1
Kosa, T; Maruyama, T; Otagiri, M; Sakai, N; Yahara, S; Yonemura, N1
Dionne, R; Singer, E1
Kivistö, KT; Lapatto-Reiniluoto, O; Neuvonen, PJ1
Apte, SS; Bapuji, AT; Rambhau, D; Rao, BR; Srinivasu, P1
Fink, M; Rossbach, A; Stiesch-Scholz, M; Tschernitschek, H1
Cai, FC; Jiang, L; Li, XJ1
Hidajat, K; Kawi, S; Song, SW1
Carballa, M; Feijoo, G; Hospido, A; Lema, JM; Moreira, M; Omil, F1
Acree, WE; Jouyban, A; Panahi-Azar, V; Shayanfar, A; Soleymani, J; York, P; Yousefi, BH1
Favaro, PD; Greifzu, F; Kalogeraki, E; Krempler, K; Löwel, S; Pielecka-Fortuna, J; Schlüter, OM1
Ascenzi, P; Coletta, M; di Masi, A; Fanali, G; Fasano, M; Gioia, M; Leboffe, L; Trezza, V1
Banaschik, R; Hammer, MU; Jablonowski, H; Kolb, JF; Lukes, P; Weltmann, KD1
Faroongsarng, D1
Doods, H; Gould, SA; Lamla, T; Pekcec, A1
Illig, K; Reed, D; Tanious, A; Wooster, M1
Azam, MW; Khan, AU; Khan, SN; Maryam, L; Sharma, A1
Azad, MA; Brancazio, D; Eccles, ME; Grela, E; Hammersmith, G; Klee, DM; Myerson, AS; Osorio, JG; Rapp, K; Sloan, R; Wang, A1
Cooper, JM; Isbister, GK; Isoardi, KZ; Keegan, M; Polanski, R1
Bandeira, PN; da Silva, AW; de Menezes, JESA; Dos Santos, HS; Ferreira, MKA; Freire, PTC; Marinho, EM; Marinho, ES; Marinho, MM; Mendes, FRS; Rebouças, EL; Rodrigues Garcia, T; Teixeira, AMR1

Reviews

2 review(s) available for diazepam and ibuprofen

ArticleYear
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

5 trial(s) available for diazepam and ibuprofen

ArticleYear
Benzodiazepine mediated antagonism of opioid analgesia.
    Pain, 1997, Volume: 71, Issue:1

    Topics: Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Anxiety Agents; Diazepam; Double-Blind Method; Drug Synergism; Female; Flumazenil; GABA Modulators; Humans; Ibuprofen; Injections, Intravenous; Male; Molar, Third; Morphine; Pain Measurement; Pain, Postoperative; Premedication; Receptors, GABA-A; Tooth Extraction

1997
A controlled evaluation of ibuprofen and diazepam for chronic orofacial muscle pain.
    Journal of orofacial pain, 1997,Spring, Volume: 11, Issue:2

    Topics: Adult; Analysis of Variance; Anti-Anxiety Agents; Anti-Inflammatory Agents, Non-Steroidal; beta-Endorphin; Diazepam; Double-Blind Method; Drug Therapy, Combination; Evaluation Studies as Topic; Facial Pain; Female; Humans; Ibuprofen; Male; Pain Measurement; Statistics, Nonparametric; Temporomandibular Joint Dysfunction Syndrome

1997
Effect of activated charcoal alone or given after gastric lavage in reducing the absorption of diazepam, ibuprofen and citalopram.
    British journal of clinical pharmacology, 1999, Volume: 48, Issue:2

    Topics: Adult; Anti-Anxiety Agents; Anti-Inflammatory Agents, Non-Steroidal; Antidotes; Area Under Curve; Charcoal; Citalopram; Cross-Over Studies; Diazepam; Female; Gastric Lavage; Humans; Ibuprofen; Intestinal Absorption; Male; Selective Serotonin Reuptake Inhibitors

1999
Time dependent influence of diazepam on the pharmacokinetics of ibuprofen in man.
    Drug metabolism and drug interactions, 1999, Volume: 15, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Chronotherapy; Cross-Over Studies; Diazepam; Drug Administration Schedule; Drug Interactions; Humans; Hypnotics and Sedatives; Ibuprofen; Male

1999
Medical and physical therapy of temporomandibular joint disk displacement without reduction.
    Cranio : the journal of craniomandibular practice, 2002, Volume: 20, Issue:2

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diazepam; Facial Pain; Female; GABA Modulators; Humans; Ibuprofen; Joint Dislocations; Male; Middle Aged; Occlusal Splints; Pain Measurement; Physical Therapy Modalities; Range of Motion, Articular; Statistics, Nonparametric; Surveys and Questionnaires; Temporomandibular Joint Disorders; Treatment Outcome

2002

Other Studies

48 other study(ies) available for diazepam and ibuprofen

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Characterization of the drug binding specificity of rat liver fatty acid binding protein.
    Journal of medicinal chemistry, 2008, Jul-10, Volume: 51, Issue:13

    Topics: Anilino Naphthalenesulfonates; Animals; Fatty Acid-Binding Proteins; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Fluorescence; Substrate Specificity

2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions.
    Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21

    Topics: Binding Sites; Crystallography, X-Ray; Drug Interactions; Humans; Pharmaceutical Preparations; Protein Binding; Protein Structure, Tertiary; Serum Albumin; Spectrometry, Fluorescence

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Stereochemical aspects of benzodiazepine binding to human serum albumin. I. Enantioselective high performance liquid affinity chromatographic examination of chiral and achiral binding interactions between 1,4-benzodiazepines and human serum albumin.
    Molecular pharmacology, 1992, Volume: 42, Issue:3

    Topics: Benzodiazepines; Caprylates; Chromatography, Affinity; Chromatography, High Pressure Liquid; Diazepam; Humans; Ibuprofen; Lauric Acids; Polymers; Serum Albumin; Stereoisomerism; Structure-Activity Relationship

1992
Paranoia in a polypharmacy setting.
    Hospital practice (Office ed.), 1992, Aug-15, Volume: 27, Issue:8

    Topics: Carisoprodol; Diazepam; Drug Therapy, Combination; Ephedrine; Haloperidol; Humans; Ibuprofen; Male; Meprobamate; Middle Aged; Phenylpropanolamine; Psychoses, Substance-Induced; Temazepam

1992
[Effect of the nonsteroidal anti-inflammatory drug 480156-S on hepatic drug-metabolizing activity and pharmacological action of diazepam and pentobarbital in rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1988, Volume: 92, Issue:4

    Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cimetidine; Cytochrome P-450 Enzyme System; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Ibuprofen; Liver; Male; Oxygenases; Pentobarbital; Phenylpropionates; Rats; Rats, Inbred Strains

1988
Shock titration in the rhesus monkey: effects of opiate and nonopiate analgesics.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:2

    Topics: Administration, Oral; Analgesics; Animals; Aspirin; Codeine; Diazepam; Dose-Response Relationship, Drug; Electroshock; Ibuprofen; Injections, Intramuscular; Isoxazoles; Male; Morphine; Narcotics; Reaction Time; Sensory Thresholds; Time Factors

1985
Acute poisoning with ibuprofen.
    Human toxicology, 1983, Volume: 2, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Aged; Child; Child, Preschool; Chlorpheniramine; Diazepam; Female; Humans; Ibuprofen; Male; Middle Aged

1983
Stereospecific and competitive binding of drugs to human serum albumin: a difference circular dichroism approach.
    Journal of pharmaceutical sciences, 1995, Volume: 84, Issue:6

    Topics: Binding, Competitive; Circular Dichroism; Diazepam; Humans; Ibuprofen; Ligands; Phenylbutazone; Protein Binding; Salicylates; Serum Albumin; Stereoisomerism

1995
Stereoselectivity and enantiomer-enantiomer interactions in the binding of ibuprofen to human serum albumin.
    Chirality, 1997, Volume: 9, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Diazepam; Digitoxin; Fluorescent Dyes; Humans; Ibuprofen; In Vitro Techniques; Kinetics; Ligands; Phenylbutazone; Protein Binding; Serum Albumin; Stereoisomerism

1997
Application of microdialysis to study the in vitro metabolism of drugs in liver microsomes.
    Journal of pharmaceutical and biomedical analysis, 1997, Volume: 16, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Diazepam; Ibuprofen; Kinetics; Microdialysis; Microsomes, Liver; Nordazepam; Rats; Salicylates; Salicylic Acid; Temazepam

1997
Species differences of serum albumins: I. Drug binding sites.
    Pharmaceutical research, 1997, Volume: 14, Issue:11

    Topics: Animals; Binding Sites; Cattle; Diazepam; Dogs; Humans; Ibuprofen; Pharmaceutical Preparations; Phenylbutazone; Protein Binding; Rabbits; Rats; Serum Albumin; Warfarin

1997
Species differences of serum albumins: III. Analysis of structural characteristics and ligand binding properties during N-B transitions.
    Pharmaceutical research, 1998, Volume: 15, Issue:4

    Topics: Animals; Binding Sites; Cattle; Diazepam; Dogs; Histidine; Humans; Hydrogen-Ion Concentration; Ibuprofen; Ligands; Phenylbutazone; Protein Conformation; Rabbits; Rats; Serum Albumin; Serum Albumin, Bovine; Species Specificity; Warfarin

1998
[Animal and clinical studies on rectal administration of a mixed solution of ibuprofen and diazepam].
    Zhonghua er ke za zhi = Chinese journal of pediatrics, 2005, Volume: 43, Issue:4

    Topics: Administration, Rectal; Animals; Child; Child, Preschool; Diazepam; Drug Therapy, Combination; Humans; Ibuprofen; Infant; Rabbits; Rats; Rats, Wistar; Seizures, Febrile

2005
Functionalized SBA-15 materials as carriers for controlled drug delivery: influence of surface properties on matrix-drug interactions.
    Langmuir : the ACS journal of surfaces and colloids, 2005, Oct-11, Volume: 21, Issue:21

    Topics: Diazepam; Drug Carriers; Drug Interactions; Drug Therapy; Ibuprofen; Microscopy, Electron; Models, Molecular; Serum Albumin, Bovine; Silicon Dioxide; Spectroscopy, Fourier Transform Infrared; Surface Properties; X-Ray Diffraction

2005
Environmental assessment of anaerobically digested sludge reuse in agriculture: potential impacts of emerging micropollutants.
    Water research, 2010, Volume: 44, Issue:10

    Topics: Anaerobiosis; Benzopyrans; Diazepam; Environmental Monitoring; Humans; Ibuprofen; Pharmaceutical Preparations; Public Health; Sulfamethoxazole; Tetrahydronaphthalenes; Waste Disposal, Fluid; Water Pollutants, Chemical

2010
Solubility prediction of drugs in mixed solvents using partial solubility parameters.
    Journal of pharmaceutical sciences, 2011, Volume: 100, Issue:10

    Topics: Clonazepam; Computer Simulation; Diazepam; Ethanol; Ibuprofen; Kinetics; Lamotrigine; Models, Molecular; Numerical Analysis, Computer-Assisted; Pharmaceutical Preparations; Phenobarbital; Propylene Glycol; Solubility; Solvents; Technology, Pharmaceutical; Temperature; Triazines; Water

2011
Environmental enrichment extends ocular dominance plasticity into adulthood and protects from stroke-induced impairments of plasticity.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Jan-21, Volume: 111, Issue:3

    Topics: Animals; Diazepam; Dominance, Ocular; Environment; Female; GABA Modulators; Ibuprofen; Interneurons; Light; Male; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Patch-Clamp Techniques; Perfusion; Stroke; Thrombosis; Time Factors; Vision, Ocular; Visual Cortex

2014
Ligand binding to the FA3-FA4 cleft inhibits the esterase-like activity of human serum albumin.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Diazepam; Diflunisal; Esterases; Esters; Humans; Hydrogen-Ion Concentration; Hydrolysis; Ibuprofen; Models, Molecular; Propofol; Serum Albumin; Tyrosine

2015
Potential of pulsed corona discharges generated in water for the degradation of persistent pharmaceutical residues.
    Water research, 2015, Nov-01, Volume: 84

    Topics: Carbamazepine; Diatrizoate; Diazepam; Diclofenac; Environmental Monitoring; Ethinyl Estradiol; Ibuprofen; Waste Disposal, Fluid; Water Pollutants, Chemical; Water Purification

2015
Assessment of the Dissociation Energetics of Some Selected Ligand Drugs Bound on Human Serum Albumin by Differential Scanning Calorimetry.
    AAPS PharmSciTech, 2016, Volume: 17, Issue:2

    Topics: Binding Sites; Calorimetry, Differential Scanning; Diazepam; Humans; Ibuprofen; Ligands; Protein Binding; Protein Denaturation; Serum Albumin; Temperature

2016
Pharmacological characterization of intraplantar Complete Freund's Adjuvant-induced burrowing deficits.
    Behavioural brain research, 2016, Mar-15, Volume: 301

    Topics: Amines; Analgesics; Animals; Antibodies; Behavior, Animal; Celecoxib; Cyclohexanecarboxylic Acids; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Freund's Adjuvant; Gabapentin; gamma-Aminobutyric Acid; Ibuprofen; Indomethacin; Inflammation; Male; Morphine; Motor Activity; Nerve Growth Factor; Pain; Rats, Wistar; Tramadol

2016
Postoperative Pain Management following Thoracic Outlet Decompression.
    Annals of vascular surgery, 2017, Volume: 44

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Decompression, Surgical; Diazepam; Drug Therapy, Combination; Female; Humans; Ibuprofen; Length of Stay; Male; Middle Aged; Narcotic Antagonists; Pain Management; Pain Measurement; Pain, Postoperative; Postoperative Care; Retrospective Studies; Thoracic Outlet Syndrome; Thoracic Surgical Procedures; Time Factors; Treatment Outcome; Young Adult

2017
Understanding the mode of binding mechanism of doripenem to human serum albumin: Spectroscopic and molecular docking approaches.
    Journal of molecular recognition : JMR, 2018, Volume: 31, Issue:7

    Topics: Anti-Bacterial Agents; Binding Sites; Binding, Competitive; Diazepam; Doripenem; Humans; Hydrogen Bonding; Ibuprofen; Indomethacin; Kinetics; Molecular Docking Simulation; Protein Binding; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Serum Albumin, Human; Solutions; Static Electricity; Temperature; Thermodynamics; Warfarin

2018
On-Demand Manufacturing of Direct Compressible Tablets: Can Formulation Be Simplified?
    Pharmaceutical research, 2019, Oct-24, Volume: 36, Issue:12

    Topics: Ciprofloxacin; Diazepam; Diphenhydramine; Doxycycline; Drug Compounding; Drug Liberation; Excipients; Ibuprofen; Particle Size; Powders; Solubility; Solvents; Tablets

2019
Duloxetine overdose causes sympathomimetic and serotonin toxicity without major complications.
    Clinical toxicology (Philadelphia, Pa.), 2022, Volume: 60, Issue:9

    Topics: Acetaminophen; Adult; Antidepressive Agents; Arrhythmias, Cardiac; Coma; Diazepam; Droperidol; Drug Overdose; Duloxetine Hydrochloride; Female; Humans; Hypotension; Ibuprofen; Middle Aged; Norepinephrine; Oxycodone; Pregabalin; Quetiapine Fumarate; Seizures; Serotonin; Sympathomimetics; Tachycardia

2022
Anxiolytic and anticonvulsant effect of Ibuprofen derivative through GABAergic neuromodulation in adult Zebrafish.
    Journal of biomolecular structure & dynamics, 2023, Volume: 41, Issue:21

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Diazepam; Humans; Ibuprofen; Seizures; Zebrafish

2023