diazepam has been researched along with histidine in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (15.79) | 18.7374 |
| 1990's | 5 (26.32) | 18.2507 |
| 2000's | 9 (47.37) | 29.6817 |
| 2010's | 1 (5.26) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Banna, NR; Kurkjian, R | 1 |
| Burch, TP; Ticku, MK | 1 |
| Chan, K; Pilling, M; Tse, J | 1 |
| Kettenmann, H; Kleingoor, C; Korpi, ER; Seeburg, PH | 1 |
| Kettenmann, H; Kleingoor, C; Korpi, ER; Seeburg, PH; Wieland, HA | 1 |
| Butterworth, RF; Rao, VL | 1 |
| Kosa, T; Maruyama, T; Otagiri, M; Sakai, N; Yahara, S; Yonemura, N | 1 |
| Benke, D; Benson, JA; Bluethmann, H; Brünig, I; Crestani, F; Fritschy, JM; Martin, JR; Möhler, H; Rudolph, U | 1 |
| Halpert, JR; He, YA; Roussel, F | 1 |
| Calame-Droz, E; Crestani, F; Prut, L; Rudolph, U; Täuber, M | 1 |
| Fradley, R; Macaulay, AJ; O'Meara, GF; Reynolds, DS; Rosahl, TW; Wafford, KA | 1 |
| Krishna, DR; Kumar, KV; Palit, G | 1 |
| Ikumi, ML; Kokwaro, GO; Muchohi, SN; Newton, CR; Ohuma, EO | 1 |
| Mueller, U; Ravelli, RB; Schönfeld, DL; Skerra, A | 1 |
| Crestani, F; Knabl, J; Rudolph, U; Zeilhofer, HU; Zeilhofer, UB | 1 |
| Balic, E; Benke, D; Fritschy, JM; Mohler, H; Rudolph, U | 1 |
| Acuña, MA; Benke, D; Ralvenius, WT; Rudolph, U; Zeilhofer, HU | 1 |
| Amundarain, MJ; Caffarena, ER; Costabel, MD | 1 |
1 review(s) available for diazepam and histidine
| Article | Year |
|---|---|
Differentiating the role of gamma-aminobutyric acid type A (GABAA) receptor subtypes.
Topics: Animals; Benzodiazepines; Binding Sites; Diazepam; Histidine; Humans; Ligands; Mice; Mice, Transgenic; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Protein Structure, Tertiary; Receptors, GABA-A | 2004 |
1 trial(s) available for diazepam and histidine
| Article | Year |
|---|---|
A modified gas-liquid chromatographic assay to monitor plasma mexiletine in a tinnitus study.
Topics: Adult; Aged; Chromatography, Gas; Diazepam; Female; Histidine; Humans; Male; Mexiletine; Middle Aged; Patient Compliance; Propylamines; Tinnitus | 1982 |
17 other study(ies) available for diazepam and histidine
| Article | Year |
|---|---|
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
A novel tremorigen antagonized by D-amphetamine.
Topics: Acetates; Aldehydes; Amines; Animals; Atropine; Calcium; Chlorpromazine; Dextroamphetamine; Diazepam; Diphenhydramine; Ganglionic Stimulants; Histidine; Male; Mice; Oximes; Phenoxybenzamine; Phenytoin; Propranolol; Scopolamine; Thiophenes; Tremor; Trimethadione | 1975 |
Histidine modification with diethyl pyrocarbonate shows heterogeneity of benzodiazepine receptors.
Topics: Animals; Benzodiazepines; Brain; Chemical Phenomena; Chemistry; Diazepam; Diethyl Pyrocarbonate; Formates; Histidine; Male; Muscimol; Pentobarbital; Rats; Receptors, Drug; Receptors, GABA-A; Receptors, Neurotransmitter | 1981 |
Benzodiazepine-induced motor impairment linked to point mutation in cerebellar GABAA receptor.
Topics: Affinity Labels; Amino Acid Sequence; Animals; Arginine; Autoradiography; Azides; Base Sequence; Benzodiazepines; Binding, Competitive; Cerebellum; Diazepam; Drug Tolerance; Ethanol; gamma-Aminobutyric Acid; Histidine; In Situ Hybridization; Kinetics; Macromolecular Substances; Models, Structural; Molecular Sequence Data; Motor Activity; Oligodeoxyribonucleotides; Point Mutation; Poly A; Protein Structure, Secondary; Rats; Rats, Mutant Strains; Receptors, GABA-A; RNA; RNA, Messenger; Tritium | 1993 |
Current potentiation by diazepam but not GABA sensitivity is determined by a single histidine residue.
Topics: Amino Acid Sequence; Animals; Cell Line; Diazepam; Dose-Response Relationship, Drug; Evoked Potentials; gamma-Aminobutyric Acid; Histidine; Humans; Kidney; Macromolecular Substances; Membrane Potentials; Mutagenesis; Rats; Receptors, GABA-A; Recombinant Proteins; Transfection | 1993 |
Characterization of binding sites for the omega3 receptor ligands [3H]PK11195 and [3H]RO5-4864 in human brain.
Topics: Allosteric Regulation; Benzodiazepines; Benzodiazepinones; Binding Sites; Binding, Competitive; Clonazepam; Convulsants; Detergents; Diazepam; Dithiothreitol; Female; Histidine; Humans; Isoquinolines; Ligands; Male; Occipital Lobe; Receptors, GABA-A; Sulfhydryl Reagents; Tritium | 1997 |
Species differences of serum albumins: III. Analysis of structural characteristics and ligand binding properties during N-B transitions.
Topics: Animals; Binding Sites; Cattle; Diazepam; Dogs; Histidine; Humans; Hydrogen-Ion Concentration; Ibuprofen; Ligands; Phenylbutazone; Protein Conformation; Rabbits; Rats; Serum Albumin; Serum Albumin, Bovine; Species Specificity; Warfarin | 1998 |
Benzodiazepine actions mediated by specific gamma-aminobutyric acid(A) receptor subtypes.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Arginine; Benzodiazepines; Diazepam; Drug Design; GABA Modulators; Histidine; Hypnotics and Sedatives; Memory; Mice; Mice, Inbred C57BL; Muscle Relaxants, Central; Point Mutation; Receptors, GABA-A | 1999 |
Analysis of homotropic and heterotropic cooperativity of diazepam oxidation by CYP3A4 using site-directed mutagenesis and kinetic modeling.
Topics: Binding Sites; Catalysis; Catalytic Domain; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Diazepam; Dose-Response Relationship, Drug; Escherichia coli; GABA Modulators; Histidine; Humans; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; Mutation; Oxygen; Plasmids; Protein Binding; Recombinant Proteins; Substrate Specificity | 2003 |
alpha2-gamma-Aminobutyric acid (GABA)A receptors are the molecular substrates mediating precipitation of narcosis but not of sedation by the combined use of diazepam and alcohol in vivo.
Topics: Anesthesia; Animals; Arginine; Behavior, Animal; Central Nervous System Depressants; Conscious Sedation; Diazepam; Ethanol; GABA Modulators; Histidine; Hypnotics and Sedatives; Male; Mice; Mice, Mutant Strains; Motor Activity; Point Mutation; Receptors, GABA-A; Reflex | 2003 |
Histaminergic H1 receptors mediate L-histidine-induced anxiety in elevated plus-maze test in mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzothiazoles; Diazepam; Dose-Response Relationship, Drug; Histamine Antagonists; Histamine H1 Antagonists; Histamine H2 Antagonists; Histidine; Male; Mice; Phenoxypropanolamines; Piperidines; Pyrilamine; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H3 | 2007 |
Response to diazepam in children with malaria-induced seizures.
Topics: Anticonvulsants; Child; Child, Preschool; Diazepam; Epilepsy; Female; Histidine; Humans; Infant; Injections, Intravenous; Malaria, Cerebral; Malaria, Falciparum; Male; Paraldehyde; Parasitemia; Receptors, GABA-A; Retrospective Studies; Risk Factors | 2008 |
The 1.8-A crystal structure of alpha1-acid glycoprotein (Orosomucoid) solved by UV RIP reveals the broad drug-binding activity of this human plasma lipocalin.
Topics: Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Diazepam; Histidine; Humans; Ligands; Lipocalins; Models, Molecular; Molecular Biology; Molecular Sequence Data; Orosomucoid; Progesterone; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Alignment; Structural Homology, Protein; Surface Properties; Ultraviolet Rays | 2008 |
Genuine antihyperalgesia by systemic diazepam revealed by experiments in GABAA receptor point-mutated mice.
Topics: Analysis of Variance; Anesthetics; Animals; Arginine; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Formaldehyde; Histidine; Hyperalgesia; Indoles; Male; Mice; Mice, Mutant Strains; Motor Activity; Physical Stimulation; Point Mutation; Protein Subunits; Pyrroles; Receptors, GABA-A | 2009 |
The alpha5(H105R) mutation impairs alpha5 selective binding properties by altered positioning of the alpha5 subunit in GABAA receptors containing two distinct types of alpha subunits.
Topics: Animals; Binding Sites; Brain; Cell Line; Cells, Cultured; Diazepam; GABA Modulators; gamma-Aminobutyric Acid; Histidine; Humans; Ligands; Mice; Mice, Transgenic; Mutation; Protein Binding; Protein Subunits; Rats; Receptors, GABA-A; Subcellular Fractions; Synaptic Transmission | 2009 |
Analgesia and unwanted benzodiazepine effects in point-mutated mice expressing only one benzodiazepine-sensitive GABAA receptor subtype.
Topics: Analgesia; Animals; Arginine; Benzodiazepines; Diazepam; GABA Modulators; Gene Expression; Histidine; Hyperalgesia; Hypnotics and Sedatives; Male; Mice; Midazolam; Pain; Pain Management; Point Mutation; Receptors, GABA-A; Spinal Cord | 2015 |
How does α
Topics: Diazepam; Flumazenil; GABA Modulators; GABA-A Receptor Antagonists; Histidine; Humans; Molecular Dynamics Simulation; Protein Conformation; Protein Subunits; Protons; Receptors, GABA-A | 2021 |