diazepam has been researched along with etomidate in 66 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (57.58) | 18.7374 |
| 1990's | 5 (7.58) | 18.2507 |
| 2000's | 9 (13.64) | 29.6817 |
| 2010's | 10 (15.15) | 24.3611 |
| 2020's | 4 (6.06) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Bidabe-Renou, AM; Caillé, JM; Constant, P; Vernet, J | 1 |
| Clarke, RS; Dundee, JW; Hegarty, JE; Zacharias, M | 1 |
| Spiess, W | 1 |
| Aromaa, U; Korttila, K; Tammisto, T | 1 |
| Carlos, R; Innerarity, S | 1 |
| Cormani, AM; Salmoiraghi, ML; Tiengo, M | 1 |
| Ho, ST; Ho, W; Hu, OY; Wang, Y; Wong, CS; Yen, MH | 1 |
| Bernards, C; Marrone, B; Priano, LL | 1 |
| Mason, DE; Muir, WW | 1 |
| Sefrin, P | 1 |
| Clyburn, P; Kay, NH; McKenzie, PJ | 1 |
| Maksay, G; Nielsen, M; Simonyi, M | 1 |
| Lehmann, KA; Mainka, F | 1 |
| Sold, M; Weis, KH | 1 |
| Launbjerg, J; Wegmann, F; Wiberg-Jørgensen, F | 1 |
| Roquefeuil, B | 1 |
| Alpert, CC; Thomas, JD | 1 |
| Müller, FO; Shipton, EA | 1 |
| Elliott, RC | 1 |
| Aromaa, U; Korttila, K | 1 |
| Dudkiewicz, J; Misterek, K | 1 |
| Doenicke, A | 1 |
| Ramanjaneyulu, R; Thyagarajan, R; Ticku, MK | 1 |
| Ashton, D | 1 |
| Clarke, RS | 1 |
| Escuret, E | 1 |
| Ramanjaneyulu, R; Ticku, MK | 1 |
| Hess, W; Schulte-Sasse, U; Tarnow, J | 1 |
| Adam, AA; Giezen, J; Helmers, JH | 2 |
| Bosch Graupera, C; Cabarrocas Gafarot, E; Noguer Coll, M; Rodríguez Moñino, A | 1 |
| Hagemeijer, F; Smalbraak, DW; Van Mechelen, R | 1 |
| Rose, NM; Ward, ME | 1 |
| Kissin, I; McGee, T; Smith, LR | 1 |
| Ashton, D; Geerts, R; Leysen, JE; Waterkeyn, C | 1 |
| Antal, M; Vydra, G | 1 |
| Beyer, E; Dittmann-Kessler, I; Doenicke, A; Sramoto, A | 1 |
| Franke, N; Kreuzer, E; Martin, E; Schmucker, P; van Ackern, K | 1 |
| Burt, D; Kamatchi, G; Uchida, I; Yang, J | 1 |
| Dukanov, M; Stratev, S; Tablov, V | 1 |
| Moon, PF | 1 |
| Behrens, R; Hofbeck, M; Lang, T; Muschweck, H; Richter, T | 1 |
| Heine, J; Jaeger, K; Marx, G; Piepenbrock, S; Scheinichen, D; Weingaertner, N | 1 |
| Asproni, B; Biggio, G; Busonero, F; Cerri, R; Maciocco, E; Mascia, MP; Pau, A; Sanna, E; Talani, G | 1 |
| Bahamonde, JA; Belda, C; Belda, J; Ferrandis, R; Llau, JV | 1 |
| Cooper, SC; Lell, WA | 1 |
| Gage, PW; Luu, T; Tierney, ML | 1 |
| Everitt, AB; Seymour, VA; Tierney, ML | 1 |
| Eggers, C; Hofer, T; Resch, R; Tilz, C | 1 |
| Fischer, F; Graw, M; Peschel, O; Thieme, D | 1 |
| Casarotto, MG; Curmi, JP; Howitt, SM; Laver, DR; Seymour, VA; Tierney, ML | 1 |
| Akk, G; Eaton, MM; Li, P; Steinbach, JH | 1 |
| Babateen, O; Bhandage, A; Birnir, B; Forsberg Nilsson, K; Jin, Z; Korol, SV; Smits, A; Uhrbom, L; Westermark, B | 1 |
| Alderson, P; Kenth, JJ; Lewis, SR; Nicholson, A; Reed, SS; Smith, AF | 1 |
| Absalom, NL; Chebib, M; Christensen, ET; Chua, HC; Hartiadi, LY; Hoestgaard-Jensen, K; Jensen, AA; Ramzan, I | 1 |
| Al-Jubouri, Q; Al-Nuaimy, W; Lopez-Luna, J; Sneddon, LU | 1 |
| Emami Zeydi, A; Habibi, MR; Heidari, N; Khademloo, M; Kiabi, FH; Sohrabi, FB; Soleimani, A | 1 |
| Cohen, JB; Forman, SA; Hoyt, H; Jayakar, SS; McGrath, M; Miller, KW; Pence, A; Raines, DE; Zhou, X | 1 |
| Gharpure, A; Hibbs, RE; Howard, RJ; Kim, JJ; Lindahl, E; Noviello, CM; Teng, J; Walsh, RM; Zhu, S; Zhuang, Y | 1 |
| Buchleithner, S; Falk-Petersen, CB; Frølund, B; Gloriam, DE; Harpsøe, K; Löffler, R; Rostrup, F; Wellendorph, P | 1 |
| Berent, J; Kaźmierski, D; Smędra, A; Wochna, K | 1 |
8 review(s) available for diazepam and etomidate
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
General anesthesia.
Topics: Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics; Diazepam; Enflurane; Etomidate; Fentanyl; Halothane; Humans; Intubation, Intratracheal; Isoflurane; Ketamine; Lorazepam; Monitoring, Physiologic; Nitrous Oxide; Surgery, Plastic; Thiopental; Tracheotomy | 1985 |
[Current intravenous anesthetics].
Topics: Anesthesia, Intravenous; Anesthetics; Anti-Anxiety Agents; Benzodiazepines; Diazepam; Etomidate; Flunitrazepam; Imidazoles; Injections, Intravenous; Lorazepam; Medazepam; Midazolam; Nordazepam | 1980 |
New drugs--boon or bane? Premedication and intravenous induction agents.
Topics: Alfaxalone Alfadolone Mixture; Anesthesia, Intravenous; Anesthetics; Animals; Benzodiazepines; Diazepam; Etomidate; Glycerol; Humans; Ketamine; Lorazepam; Male; Mice; Phenols; Preanesthetic Medication; Propofol; Thiopental; Thrombophlebitis | 1983 |
[Effect of anesthetics on cerebral perfusion pressure].
Topics: Alfaxalone Alfadolone Mixture; Anesthetics; Animals; Barbiturates; Blood Pressure; Cerebrovascular Circulation; Diazepam; Dogs; Enflurane; Etomidate; Halothane; Humans; Intracranial Pressure; Methoxyflurane; Nitrous Oxide | 1983 |
[Effect of anesthetics on intracranial pressure].
Topics: Alfaxalone Alfadolone Mixture; Anesthetics; Animals; Barbiturates; Brain; Cerebrovascular Circulation; Diazepam; Dogs; Droperidol; Drug Combinations; Etomidate; Fentanyl; Halothane; Humans; Intracranial Pressure; Ketamine; Nitrous Oxide; Oxygen Consumption; Sodium Oxybate | 1981 |
Anaesthetic and sedative agents used for electrical cardioversion.
Topics: Anesthetics; Apnea; Diazepam; Electric Countershock; Etomidate; Fentanyl; Humans; Hypnotics and Sedatives; Hypotension; Mental Recall; Methyl Ethers; Midazolam; Piperidines; Propofol; Randomized Controlled Trials as Topic; Remifentanil; Sevoflurane; Thiopental | 2015 |
Suicide committed by a paramedic using a cocktail of drugs: Morphine, etomidate, diazepam and rocuronium. Case report and review of literature.
Topics: Allied Health Personnel; Diazepam; Etomidate; Humans; Morphine; Pharmaceutical Preparations; Rocuronium; Suicide, Assisted | 2021 |
15 trial(s) available for diazepam and etomidate
| Article | Year |
|---|---|
Effect of preanaesthetic medication on etomidate.
Topics: Adolescent; Adult; Anesthesia, Intravenous; Diazepam; Drug Interactions; Etomidate; Female; Humans; Imidazoles; Meperidine; Middle Aged; Preanesthetic Medication; Time Factors | 1979 |
[R 33812 (domperidon) i.v. and orally as antiemetic adjuvans for short anaesthetics induced with etomidate. A comparative study (author's transl)].
Topics: Adjuvants, Anesthesia; Administration, Oral; Antiemetics; Benzimidazoles; Diazepam; Dilatation and Curettage; Drug Interactions; Etomidate; Female; Humans; Injections, Intravenous; Piperidines; Premedication | 1979 |
Comparison of etomidate in combination with fentanyl or diazepam, with thiopentone as an induction agent for general anaesthesia.
Topics: Adult; Anesthesia, General; Diazepam; Etomidate; Fentanyl; Humans; Imidazoles; Middle Aged; Movement; Muscles; Pain; Thiopental | 1979 |
Effect of premedication on etomidate anaesthesia.
Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Atropine; Diazepam; Etomidate; Fentanyl; Humans; Imidazoles; Middle Aged; Pain; Preanesthetic Medication | 1979 |
Effects of diazepam and midazolam on recovery from anaesthesia in outpatients.
Topics: Adult; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics; Benzodiazepines; Diazepam; Etomidate; Female; Humans; Midazolam; Postoperative Period | 1986 |
Ventilatory CO2-response after alfentanil and sedative premedication (etomidate, diazepam and droperidol). A comparative study with human volunteers.
Topics: Adult; Alfentanil; Anesthetics; Carbon Dioxide; Diazepam; Droperidol; Drug Combinations; Drug Interactions; Etomidate; Female; Fentanyl; Humans; Hypnotics and Sedatives; Male; Preanesthetic Medication; Respiration | 1986 |
Alfentanil or fentanyl for anaesthetic procedures of two hours duration? A double-blind study.
Topics: Adjuvants, Anesthesia; Adult; Alfentanil; Analgesics; Anesthesia, Endotracheal; Diazepam; Double-Blind Method; Etomidate; Female; Fentanyl; Genital Diseases, Female; Hemodynamics; Humans; Middle Aged; Random Allocation | 1987 |
[Total intravenous anesthesia with phentanyl-diazepam-etomidate. A controlled study].
Topics: Abortion, Induced; Adolescent; Adult; Anesthesia, Intravenous; Clinical Trials as Topic; Diazepam; Etomidate; Female; Fentanyl; Humans; Middle Aged; Nitrous Oxide; Pregnancy; Thiopental | 1987 |
[Hemodynamic analysis of 6 different anesthesia induction procedures in coronary surgery patients].
Topics: Alfaxalone Alfadolone Mixture; Anesthesia, Intravenous; Coronary Artery Bypass; Coronary Disease; Diazepam; Etomidate; Fentanyl; Flunitrazepam; Hemodynamics; Humans; Ketamine; Myocardium; Oxygen Consumption; Preanesthetic Medication; Thiopental | 1982 |
Pain and myoclonus during induction with etomidate. A double-blind, controlled evaluation of the influence of droperidol and fentanyl.
Topics: Adolescent; Adult; Aged; Anesthesia; Clinical Trials as Topic; Diazepam; Double-Blind Method; Droperidol; Etomidate; Female; Fentanyl; Humans; Imidazoles; Male; Middle Aged; Myoclonus; Pain; Preanesthetic Medication | 1981 |
Fentanyl-etomidate anesthesia for cardioversion.
Topics: Adult; Aged; Anesthesia; Clinical Trials as Topic; Diazepam; Electric Countershock; Etomidate; Female; Fentanyl; Humans; Imidazoles; Male; Middle Aged; Naloxone | 1982 |
Outpatient sedation for oral surgery. A new technique using etomidate.
Topics: Adult; Ambulatory Surgical Procedures; Anesthesia, Intravenous; Clinical Trials as Topic; Diazepam; Double-Blind Method; Etomidate; Female; Humans; Imidazoles; Male; Middle Aged; Pentazocine; Pilot Projects; Surgery, Oral | 1982 |
[Ketamine at low doses + etomidate or diazepam--a comparative clinical study of anesthesia in urology].
Topics: Aged; Anesthetics, Dissociative; Anesthetics, Intravenous; Diazepam; Drug Therapy, Combination; Etomidate; Fentanyl; Humans; Ketamine; Middle Aged; Urologic Diseases | 1995 |
Hormonal effects of an induction dose of etomidate for patients undergoing urgent myocardial revascularization.
Topics: Aged; Anesthetics, Intravenous; Blood Pressure; Diazepam; Epinephrine; Etomidate; Female; Heart Rate; Humans; Hydrocortisone; Intubation, Intratracheal; Male; Middle Aged; Myocardial Revascularization; Norepinephrine; Prospective Studies; Time Factors | 1988 |
Comparing Hemodynamic Responses to Diazepam, Propofol and Etomidate During Anesthesia Induction in Patients with Left Ventricular Dysfunction Undergoing Coronary Artery Bypass Graft Surgery: a Double-blind, Randomized Clinical Trial.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Coronary Artery Bypass; Diazepam; Double-Blind Method; Etomidate; Female; Hemodynamics; Humans; Male; Middle Aged; Propofol; Ventricular Dysfunction, Left | 2017 |
43 other study(ies) available for diazepam and etomidate
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
[Vasoreactivity of cerebral infarct to barbiturates and other intravenous anesthetics].
Topics: Alfaxalone Alfadolone Mixture; Anesthetics; Brain; Carbon Dioxide; Cerebral Infarction; Cerebrovascular Circulation; Diazepam; Etomidate; Fentanyl; Humans; Oxygen Consumption; Thiopental; Vasoconstriction | 1978 |
[Preliminary clinical observations on the use of the narcotic, Etomidate, in anesthesiology. Evaluation of the MPC dose and equivalent dose].
Topics: Adolescent; Adult; Anesthesia; Diazepam; Dose-Response Relationship, Drug; Etomidate; Humans; Imidazoles; Ketamine; Middle Aged; Pain; Propanidid; Thiopental | 1979 |
Effect of physostigmine on the loss of consciousness induced by midazolam, etomidate and althesin.
Topics: Adult; Alfaxalone Alfadolone Mixture; Anesthesia Recovery Period; Diazepam; Drug Interactions; Etomidate; Female; Humans; Male; Midazolam; Middle Aged; Physostigmine; Protein Binding | 1991 |
Effect of anesthetic induction agents on cardiovascular neuroregulation in dogs.
Topics: Anesthetics; Animals; Blood Pressure; Carbon Dioxide; Diazepam; Dogs; Etomidate; Female; Heart Rate; Ketamine; Male; Pressoreceptors; Thiopental | 1989 |
Side effects of etomidate in dogs.
Topics: Acepromazine; Anesthesia, Intravenous; Animals; Diazepam; Dogs; Dose-Response Relationship, Drug; Etomidate; Female; Heart Rate; Male; Morphine; Preanesthetic Medication; Respiration; Time Factors | 1989 |
[Narcosis within the scope of preclinical care].
Topics: Analgesia; Anesthesia, General; Carbon Dioxide; Diazepam; Emergencies; Etomidate; First Aid; Hemodynamics; Humans; Intracranial Pressure; Ketamine; Methohexital; Oxygen; Risk; Thiopental; Wounds and Injuries | 1985 |
The enhancement of diazepam and muscimol binding by pentobarbital and (+)-etomidate: size of the molecular arrangement estimated by electron irradiation inactivation of rat cortex.
Topics: Animals; Cerebral Cortex; Diazepam; Etomidate; gamma-Aminobutyric Acid; In Vitro Techniques; Molecular Weight; Muscimol; Pentobarbital; Rats; Receptors, GABA-A | 1986 |
[Cerebral ischemia, anesthetic agents and cerebral metabolic protection].
Topics: Alfaxalone Alfadolone Mixture; Anesthetics; Barbiturates; Brain; Brain Ischemia; Diazepam; Etomidate; Humans; Ketamine; Midazolam | 1987 |
Severe mefenamic acid poisoning. A case report.
Topics: Adolescent; Diazepam; Etomidate; Female; Humans; Mefenamic Acid | 1985 |
The action of intravenous anaesthetic and central depressant drugs on the contractures elicited by tetraethylammonium in the chick biventer cervicis muscle.
Topics: Alfaxalone Alfadolone Mixture; Anesthetics; Animals; Central Nervous System Depressants; Chickens; Chloralose; Diazepam; Drug Synergism; Ethanol; Etomidate; In Vitro Techniques; Methohexital; Muscle Contraction; Neck Muscles; Paraldehyde; Pregnanediones; Propanidid; Tetraethylammonium; Tetraethylammonium Compounds; Thiopental; Urethane | 1985 |
Venous complications after intravenous injection of diazepam, flunitrazepam, thiopentone and etomidate.
Topics: Adult; Anesthesia, Intravenous; Anti-Anxiety Agents; Diazepam; Double-Blind Method; Etomidate; Female; Flunitrazepam; Humans; Imidazoles; Injections, Intravenous; Male; Middle Aged; Phlebitis; Random Allocation; Thiopental; Thrombophlebitis | 1980 |
[Etomidate, propanidid, gamma-hydroxy butyric acid].
Topics: Anesthesia, General; Blood Pressure; Diazepam; Drug Interactions; Etomidate; Heart Rate; Histamine H1 Antagonists; Humans; Hydroxybutyrates; Imidazoles; Partial Pressure; Propanidid; Sodium Oxybate | 1981 |
Enhancement of diazepam and gamma-aminobutyric acid binding by (+)etomidate and pentobarbital.
Topics: Animals; Cell Membrane; Cerebellum; Cerebral Cortex; Diazepam; Etomidate; gamma-Aminobutyric Acid; Imidazoles; Kinetics; Male; Pentobarbital; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Diazepam, pentobarbital and D-etomidate produced increases in bicuculline seizure threshold; selective antagonism by RO15-1788, picrotoxin and (+/-)-DMBB.
Topics: Animals; Barbiturates; Benzodiazepinones; Bicuculline; Diazepam; Etomidate; Flumazenil; Imidazoles; Male; Pentobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Seizures | 1983 |
Binding characteristics and interactions of depressant drugs with [35S]t-butylbicyclophosphorothionate, a ligand that binds to the picrotoxinin site.
Topics: Animals; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Convulsants; Diazepam; Etomidate; gamma-Aminobutyric Acid; Male; Membranes; Pentobarbital; Picrotoxin; Psychotropic Drugs; Rats; Rats, Inbred Strains; Sesterterpenes | 1984 |
An evaluation of etomidate in total intravenous anesthesia (TIVA).
Topics: Adolescent; Adult; Aged; Anesthesia, Intravenous; Blood Pressure; Bronchoscopy; Diazepam; Etomidate; Female; Heart Rate; Humans; Imidazoles; Laryngoscopy; Male; Middle Aged; Preanesthetic Medication; Time Factors | 1981 |
The indices of potency for intravenous anaesthetics.
Topics: Anesthesia, Intravenous; Anesthetics; Animals; Diazepam; Dose-Response Relationship, Drug; Etomidate; Male; Postural Balance; Rats; Rats, Inbred Strains; Reflex; Thiopental | 1981 |
Etomidate stereospecifically stimulates forebrain, but not cerebellar, 3H-diazepam binding.
Topics: Animals; Brain; Cerebellum; Diazepam; Etomidate; Female; gamma-Aminobutyric Acid; Imidazoles; Isoxazoles; Muscimol; Rats; Rats, Inbred Strains; Stereoisomerism; Synaptic Membranes | 1981 |
[Induction of neuroleptic anesthesia with etomidate].
Topics: Aged; Blood Circulation; Blood Pressure; Diazepam; Droperidol; Etomidate; Female; Fentanyl; Humans; Imidazoles; Male; Middle Aged; Neuroleptanalgesia; Preanesthetic Medication | 1981 |
[Etomidate and suxamethonium. The duration of relaxation and pseudocholinesterase activity. A clinical experimental study (author's transl)].
Topics: Adult; Anesthesia, General; Butyrylcholinesterase; Cholinesterases; Diazepam; Etomidate; Humans; Imidazoles; Male; Muscle Relaxation; Preanesthetic Medication; Succinylcholine; Ulnar Nerve | 1980 |
[Hemodynamics and myocardial O2 consumption at induction of anesthesia (author's transl)].
Topics: Anesthesia, General; Diazepam; Etomidate; Fentanyl; Hemodynamics; Humans; Middle Aged; Myocardium; Oxygen Consumption; Pancuronium | 1980 |
Etomidate potentiation of GABAA receptor gated current depends on the subunit composition.
Topics: Action Potentials; Animals; Cells, Cultured; Diazepam; Etomidate; gamma-Aminobutyric Acid; Patch-Clamp Techniques; Receptors, GABA; Receptors, GABA-A | 1995 |
Cortisol suppression in cats after induction of anesthesia with etomidate, compared with ketamine-diazepam combination.
Topics: Anesthesia; Animals; Body Temperature; Cats; Diazepam; Drug Combinations; Etomidate; Female; Heart Rate; Hydrocortisone; Ketamine; Male; Respiration; Systole; Tidal Volume | 1997 |
Percutaneous endoscopic gastrostomy in children and adolescents.
Topics: Adolescent; Adult; Child; Child, Preschool; Diazepam; Duodenum; Endoscopy; Enteral Nutrition; Etomidate; Female; Gastrostomy; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Jejunostomy; Male; Midazolam; Postoperative Complications | 1997 |
Effects of different preparations of propofol, diazepam, and etomidate on human neutrophils in vitro.
Topics: Anesthetics, Intravenous; Diazepam; Erythrocytes; Etomidate; Flow Cytometry; Humans; In Vitro Techniques; Neutrophils; Phagocytosis; Propofol; Respiratory Burst; Triglycerides | 2001 |
Ethyl 2-(4-bromophenyl)-1-(2,4-dichlorophenyl)-1H-4-imidazolecarboxylate is a novel positive modulator of GABAA receptors.
Topics: Animals; Binding, Competitive; Cell Membrane; Cerebral Cortex; Diazepam; Dose-Response Relationship, Drug; Etomidate; Female; Flunitrazepam; GABA Modulators; gamma-Aminobutyric Acid; Glycine; Humans; Hydrocarbons, Halogenated; Imidazoles; Male; Membrane Potentials; Oocytes; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Glycine; Receptors, Serotonin, 5-HT3; Serotonin; Tritium; Xenopus laevis | 2005 |
Anesthesia for cardiac surgery on a patient with stiff person syndrome.
Topics: Adult; Analgesics, Opioid; Anesthesia; Anesthetics, Intravenous; Anticonvulsants; Cardiopulmonary Bypass; Diazepam; Etomidate; Female; Fentanyl; Heart Valve Diseases; Heparin; Humans; Midazolam; Morphine; Neuromuscular Nondepolarizing Agents; Pain, Postoperative; Pancuronium; Piperidines; Propofol; Remifentanil; Stiff-Person Syndrome | 2005 |
Functional asymmetry of the conserved cystine loops in alphabetagamma GABA A receptors revealed by the response to GABA activation and drug potentiation.
Topics: Amino Acid Motifs; Amino Acid Sequence; Cell Line; Cystine; Diazepam; Drug Synergism; Etomidate; GABA Modulators; gamma-Aminobutyric Acid; Humans; Ion Channel Gating; Molecular Sequence Data; Patch-Clamp Techniques; Pentobarbital; Proline; Protein Conformation; Receptors, GABA-A; Receptors, GABA-B | 2008 |
Differential drug responses on native GABA(A) receptors revealing heterogeneity in extrasynaptic populations in cultured hippocampal neurons.
Topics: Animals; Cells, Cultured; Diazepam; Electrophysiology; Etomidate; GABA Modulators; Hippocampus; Ion Channel Gating; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, GABA-A | 2009 |
Successful treatment for refractory convulsive status epilepticus by non-parenteral lacosamide.
Topics: Acetamides; Adult; Anticonvulsants; Diazepam; Drug Resistance; Drug Therapy, Combination; Epilepsy; Etomidate; Humans; Lacosamide; Levetiracetam; Male; Midazolam; Piracetam; Practice Guidelines as Topic; Status Epilepticus; Treatment Outcome | 2010 |
Multi target analysis of putrefactive specimens by liquid chromatography-tandem mass spectrometry to prove multiple poisonings by hypnotics and muscle relaxants.
Topics: Androstanols; Autopsy; Chromatography, High Pressure Liquid; Diazepam; Etomidate; Exhumation; Hospitals; Humans; Hypnotics and Sedatives; Midazolam; Neuromuscular Nondepolarizing Agents; Rocuronium; Tandem Mass Spectrometry; Toxicology | 2009 |
Selective modulation of different GABAA receptor isoforms by diazepam and etomidate in hippocampal neurons.
Topics: Amino Acid Sequence; Animals; Diazepam; Electric Conductivity; Etomidate; Female; Hippocampus; Hydrophobic and Hydrophilic Interactions; Male; Models, Molecular; Molecular Sequence Data; Neurons; Permeability; Protein Isoforms; Protein Structure, Secondary; Rats; Rats, Wistar; Receptors, GABA-A | 2012 |
The benzodiazepine diazepam potentiates responses of α1β2γ2L γ-aminobutyric acid type A receptors activated by either γ-aminobutyric acid or allosteric agonists.
Topics: Anesthetics; Animals; Binding Sites; Diazepam; Drug Synergism; Etomidate; GABA Modulators; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Patch-Clamp Techniques; Pentobarbital; Pregnanediones; Rats; Receptors, GABA-A | 2013 |
Etomidate, propofol and diazepam potentiate GABA-evoked GABAA currents in a cell line derived from human glioblastoma.
Topics: Anesthetics, General; Cell Line, Tumor; Diazepam; Drug Synergism; Electrophysiological Phenomena; Etomidate; gamma-Aminobutyric Acid; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Ion Channel Gating; Isoxazoles; Propofol; Protein Subunits; Protein Transport; Receptors, GABA-A | 2015 |
Kavain, the Major Constituent of the Anxiolytic Kava Extract, Potentiates GABAA Receptors: Functional Characteristics and Molecular Mechanism.
Topics: Anesthetics; Animals; Anti-Anxiety Agents; Benzodiazepines; Diazepam; Drug Interactions; Drug Synergism; Etomidate; Flumazenil; Humans; Kava; Mutation; Propofol; Protein Subunits; Pyrones; Receptors, GABA-A; Xenopus laevis | 2016 |
Impact of stress, fear and anxiety on the nociceptive responses of larval zebrafish.
Topics: Acetic Acid; Analgesics; Animals; Anxiety; Behavior, Animal; Caffeine; Diazepam; Etomidate; Fear; Larva; Stress, Physiological; Swimming; Zebrafish | 2017 |
Competitive Antagonism of Etomidate Action by Diazepam: In Vitro GABAA Receptor and In Vivo Zebrafish Studies.
Topics: Animals; Diazepam; Drug Antagonism; Etomidate; Hypnotics and Sedatives; Models, Animal; Receptors, GABA; Zebrafish | 2020 |
Shared structural mechanisms of general anaesthetics and benzodiazepines.
Topics: Allosteric Regulation; Anesthetics, General; Barbiturates; Benzodiazepines; Bicuculline; Binding Sites; Binding, Competitive; Cryoelectron Microscopy; Diazepam; Electrophysiology; Etomidate; Flumazenil; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Ligands; Models, Molecular; Molecular Conformation; Molecular Dynamics Simulation; Phenobarbital; Picrotoxin; Propofol; Receptors, GABA-A | 2020 |
Molecular Determinants Underlying Delta Selective Compound 2 Activity at
Topics: Allosteric Regulation; Benzamides; Binding Sites; Diazepam; Etomidate; HEK293 Cells; Humans; Imidazoles; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Multiprotein Complexes; Mutagenesis, Site-Directed; Protein Binding; Protein Domains; Receptors, GABA-A | 2021 |