diazepam and diclofenac

diazepam has been researched along with diclofenac in 45 studies

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.22)18.7374
1990's3 (6.67)18.2507
2000's19 (42.22)29.6817
2010's18 (40.00)24.3611
2020's4 (8.89)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Topliss, JG; Yoshida, F1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Chang, TK; Ensom, MH; Kiang, TK1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Carrupt, PA; Martel, S; Ottaviani, G1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Briand, X; Faller, B; Lázaro, E; Lowe, PJ1
Lombardo, F; Obach, RS; Waters, NJ1
Chuang, S; Horne, J; Porter, CJ; Scanlon, MJ; Velkov, T1
Axe, FU; Bembenek, SD; Butler, CR; Coles, F; Dunford, PJ; Edwards, JP; Fourie, AM; Grice, CA; Karlsson, L; Lundeen, K; Riley, JP; Savall, BM; Tays, KL; Wei, J; Williams, KN; Xue, X1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Avdeef, A; Tam, KY1
Glen, RC; Lowe, R; Mitchell, JB1
Claxton, CR; Curran, RE; Harradine, PJ; Hutchison, L; Littlewood, P; Martin, IJ1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Artursson, P; Mateus, A; Matsson, P1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bajusz, D; Balogh, GT; Dargó, G; Müller, J; Simon, K1
Balliano, TL; Barbosa, G; Carvalho, VF; da Silva, BA; de Souza, ET; Lima, LM; Martins, IRR; Martins, MA; Medeiros, MM; Moraes Junior, MO; Nunes, IKDC; Silva, PMR; Silva, SWD1
Asano, M; Maekawa, N; Mikawa, K; Nishina, K; Obara, H1
Russeva, V; Zhivkova, Z1
Baer, GA; Filatov, SM; Oikkonen, M; Rorarius, MG1
Bhattcharyya, D; Sur, TK1
Shou, M1
Andersson, TB; Bredberg, E; Eriksson, UG; Eriksson-Lepkowska, M; Frison, L; Johansson, S; Larsson, M; Thuresson, A1
Nze, PU; Onyekwulu, F1
Carballa, M; Lema, JM; Omil, F; Ternes, T1
Cihal, P; Kamyar, MR; Lemmens-Gruber, R; Nemec, K; Timin, E1
Coleman, HM; Khan, SJ; Le-Clech, P; Stuetz, RM; Trinh, T; van den Akker, B1
Mori, T; Shibasaki, M; Shimizu, N; Suzuki, T1
Barthó, L; Benkó, R; Bölcskei, K; Boros, M; Pethő, G; Szolcsányi, J1
Banaschik, R; Hammer, MU; Jablonowski, H; Kolb, JF; Lukes, P; Weltmann, KD1
Coitinho, AS; Glassmann, D; Gomez, R; Marafon, P; Pereira, P; Vieira, V1
Baron, MG; Hetheridge, MJ; Jackson, SK; Jha, AN; Mintram, KS; Moody, AJ; Owen, SF; Purcell, WM1
Ito, S; Iwamoto, K; Kamimura, H; Mizunaga, M; Nakayama, K; Negoro, T; Nishiwaki, M; Nomura, Y; Suemizu, H; Yamazaki, H; Yoneda, N1
Akunal Türel, C; Çelik, H; Çetinkaya, A; Türel, İ1

Reviews

3 review(s) available for diazepam and diclofenac

ArticleYear
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Evidence-based intravenous pain treatment with analgesic infusion regimens.
    Arzneimittel-Forschung, 2010, Volume: 60, Issue:5

    Topics: Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Diazepam; Diclofenac; Drug Interactions; Evidence-Based Medicine; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Pain; Pharmaceutical Solutions; Pharmaceutical Vehicles; Tramadol; Vitamin B Complex; Vitamins

2010

Trials

4 trial(s) available for diazepam and diclofenac

ArticleYear
Oral clonidine premedication reduces vomiting in children after strabismus surgery.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1995, Volume: 42, Issue:11

    Topics: Administration, Oral; Adrenergic alpha-Agonists; Anesthesia, Inhalation; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Child; Child, Preschool; Clonidine; Diazepam; Diclofenac; Double-Blind Method; Female; Humans; Incidence; Length of Stay; Male; Midazolam; Neuromuscular Nondepolarizing Agents; Pain, Postoperative; Placebos; Postoperative Complications; Preanesthetic Medication; Premedication; Prospective Studies; Strabismus; Vecuronium Bromide; Vomiting

1995
Efficacy and safety of premedication with oral ketamine for day-case adenoidectomy compared with rectal diazepam/diclofenac and EMLA.
    Acta anaesthesiologica Scandinavica, 2000, Volume: 44, Issue:1

    Topics: Adenoidectomy; Adjuvants, Anesthesia; Administration, Oral; Administration, Rectal; Ambulatory Surgical Procedures; Anesthetics; Anesthetics, Combined; Child, Preschool; Diazepam; Diclofenac; Glycopyrrolate; Humans; Infant; Ketamine; Lidocaine; Lidocaine, Prilocaine Drug Combination; Preanesthetic Medication; Prilocaine

2000
Ximelagatran, an oral direct thrombin inhibitor, has a low potential for cytochrome P450-mediated drug-drug interactions.
    Clinical pharmacokinetics, 2003, Volume: 42, Issue:8

    Topics: Administration, Oral; Adult; Aged; Amidines; Anticoagulants; Area Under Curve; Azetidines; Benzylamines; Cross-Over Studies; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diazepam; Diclofenac; Drug Interactions; Glycine; Humans; In Vitro Techniques; Infusions, Intravenous; Microsomes, Liver; Middle Aged; Nifedipine; Nordazepam; Prodrugs; Thrombin

2003
Intraoperative diclofenac for post-adenoidectomy analgesia in small children.
    Nigerian journal of clinical practice, 2006, Volume: 9, Issue:2

    Topics: Adenoidectomy; Analgesia; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Diazepam; Diclofenac; Female; Humans; Infant; Intraoperative Care; Male; Pain Measurement; Pain, Postoperative; Time Factors

2006

Other Studies

38 other study(ies) available for diazepam and diclofenac

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities.
    Journal of medicinal chemistry, 2007, Feb-22, Volume: 50, Issue:4

    Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water

2007
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
New approach to measure protein binding based on a parallel artificial membrane assay and human serum albumin.
    Journal of medicinal chemistry, 2008, Apr-10, Volume: 51, Issue:7

    Topics: Humans; Kinetics; Membranes, Artificial; Permeability; Protein Binding; Serum Albumin

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Characterization of the drug binding specificity of rat liver fatty acid binding protein.
    Journal of medicinal chemistry, 2008, Jul-10, Volume: 51, Issue:13

    Topics: Anilino Naphthalenesulfonates; Animals; Fatty Acid-Binding Proteins; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Fluorescence; Substrate Specificity

2008
Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity.
    Journal of medicinal chemistry, 2008, Jul-24, Volume: 51, Issue:14

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Catalysis; Dogs; Drug Evaluation, Preclinical; Enzyme Inhibitors; Epoxide Hydrolases; Humans; Magnetic Resonance Spectroscopy; Mice; Structure-Activity Relationship

2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Control and measurement of plasma pH in equilibrium dialysis: influence on drug plasma protein binding.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Blood Proteins; Buffers; Carbon Dioxide; Chemical Phenomena; Dialysis; Dogs; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Macaca fascicularis; Mice; Osmolar Concentration; Pharmaceutical Preparations; Protein Binding; Rats; Reproducibility of Results

2011
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
Human Serum Albumin Binding in a Vial: A Novel UV-pH Titration Method To Assist Drug Design.
    Journal of medicinal chemistry, 2020, 02-27, Volume: 63, Issue:4

    Topics: Binding Sites; Chemistry, Pharmaceutical; Drug Design; Humans; Hydrogen-Ion Concentration; Molecular Docking Simulation; Pharmaceutical Preparations; Protein Binding; Serum Albumin, Human; Spectrophotometry, Ultraviolet; Titrimetry

2020
Discovery of sulfonyl hydrazone derivative as a new selective PDE4A and PDE4D inhibitor by lead-optimization approach on the prototype LASSBio-448: In vitro and in vivo preclinical studies.
    European journal of medicinal chemistry, 2020, Oct-15, Volume: 204

    Topics: Animals; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Drug Design; Enzyme Inhibitors; Humans; Hydrazones; Hypersensitivity; Lung; Male; Mice

2020
New mathematical approach for the evaluation of drug binding to human serum albumin by high-performance liquid affinity chromatography.
    Journal of chromatography. B, Biomedical sciences and applications, 1998, Apr-10, Volume: 707, Issue:1-2

    Topics: Anti-Anxiety Agents; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Binding, Competitive; Chromatography, Affinity; Chromatography, High Pressure Liquid; Diazepam; Diclofenac; Humans; Models, Theoretical; Pharmaceutical Preparations; Protein Binding; Serum Albumin

1998
Effect of Panax ginseng and diazepam on brain 5-hydroxytryptamine and its modification by diclofenac in rat.
    Indian journal of physiology and pharmacology, 1999, Volume: 43, Issue:4

    Topics: Animals; Anti-Anxiety Agents; Brain; Corticosterone; Diazepam; Diclofenac; Male; Panax; Plants, Medicinal; Rats; Rats, Wistar; Serotonin; Stress, Physiological

1999
Kinetic analysis for multiple substrate interaction at the active site of cytochrome P450.
    Methods in enzymology, 2002, Volume: 357

    Topics: Benzoflavones; Binding Sites; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diazepam; Diclofenac; Enzyme Activation; Enzyme Inhibitors; Kinetics; Losartan; Models, Biological; Protein Binding; Quinidine; Recombinant Proteins

2002
Fate of pharmaceutical and personal care products (PPCPs) during anaerobic digestion of sewage sludge.
    Water research, 2007, Volume: 41, Issue:10

    Topics: Anaerobiosis; Cosmetics; Diazepam; Diclofenac; Estrogens; Pharmaceutical Preparations; Self Care; Sewage; Temperature; Waste Disposal, Fluid; Water Pollutants, Chemical

2007
Removal of trace organic chemical contaminants by a membrane bioreactor.
    Water science and technology : a journal of the International Association on Water Pollution Research, 2012, Volume: 66, Issue:9

    Topics: Amitriptyline; Bioreactors; Carbamazepine; Diazepam; Diclofenac; Fluoxetine; Gemfibrozil; Omeprazole; Organic Chemicals; Pharmaceutical Preparations; Sulfamethoxazole; Trimethoprim; Waste Disposal, Fluid; Water Pollutants, Chemical

2012
Involvement of the arachidonic acid cascade in the hypersusceptibility to pentylenetetrazole-induced seizure during diazepam withdrawal.
    Biological & pharmaceutical bulletin, 2012, Volume: 35, Issue:12

    Topics: Animals; Arachidonic Acid; Convulsants; Cyclooxygenase Inhibitors; Diazepam; Diclofenac; Enzyme Inhibitors; Lipoxygenase; Lipoxygenase Inhibitors; Male; Masoprocol; Mice; Mice, Inbred Strains; Pentylenetetrazole; Phospholipase A2 Inhibitors; Prostaglandin-Endoperoxide Synthases; Psychotropic Drugs; Quinacrine; Seizures; Substance Withdrawal Syndrome

2012
Effects of reference analgesics and psychoactive drugs on the noxious heat threshold of mice measured by an increasing-temperature water bath.
    Basic & clinical pharmacology & toxicology, 2013, Volume: 113, Issue:6

    Topics: Analgesics; Animals; Diazepam; Diclofenac; Dipyrone; Dose-Response Relationship, Drug; Droperidol; Female; Hot Temperature; Mice; Morphine; Motor Activity; Psychotropic Drugs; Sensory Thresholds; Thermosensing

2013
Potential of pulsed corona discharges generated in water for the degradation of persistent pharmaceutical residues.
    Water research, 2015, Nov-01, Volume: 84

    Topics: Carbamazepine; Diatrizoate; Diazepam; Diclofenac; Environmental Monitoring; Ethinyl Estradiol; Ibuprofen; Waste Disposal, Fluid; Water Pollutants, Chemical; Water Purification

2015
Effect of diclofenac sodium on seizures and inflammatory profile induced by kindling seizure model.
    Epilepsy research, 2016, Volume: 127

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Cerebral Cortex; Diazepam; Diclofenac; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; Hippocampus; Interleukin-1beta; Interleukin-6; Kindling, Neurologic; Male; Motor Activity; Rats, Wistar; Seizures; Tumor Necrosis Factor-alpha

2016
Pharmaceutical Metabolism in Fish: Using a 3-D Hepatic In Vitro Model to Assess Clearance.
    PloS one, 2017, Volume: 12, Issue:1

    Topics: Animals; Atenolol; Biotransformation; Carbamazepine; Diazepam; Diclofenac; Drug Evaluation, Preclinical; Female; Kinetics; Liver; Metoprolol; Models, Animal; Oncorhynchus mykiss; Phenylbutazone; Propranolol; Tandem Mass Spectrometry; Water Pollutants, Chemical; Xenobiotics

2017
Predicted values for human total clearance of a variety of typical compounds with differently humanized-liver mouse plasma data.
    Drug metabolism and pharmacokinetics, 2020, Volume: 35, Issue:4

    Topics: Acetamides; Albuterol; Animals; Carbamates; Chromatography, Liquid; Diazepam; Diclofenac; Digitoxin; Humans; Itraconazole; Ketoprofen; Liver; Metabolic Clearance Rate; Mice; Mice, Transgenic; Naproxen; Pharmaceutical Preparations; Phenytoin; Piperidines; Pravastatin; Pyrimidines; Quinidine; Tandem Mass Spectrometry; Telmisartan; Terfenadine; Verapamil

2020
Electrophysiologic and anti-inflammatorial effects of cyclooxygenase inhibition in epileptiform activity.
    Physiological reports, 2023, Volume: 11, Issue:17

    Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Diazepam; Diclofenac; Interleukin-6; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha

2023