diazepam has been researched along with clonazepam in 315 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 155 (49.21) | 18.7374 |
| 1990's | 82 (26.03) | 18.2507 |
| 2000's | 37 (11.75) | 29.6817 |
| 2010's | 25 (7.94) | 24.3611 |
| 2020's | 16 (5.08) | 2.80 |
| Authors | Studies |
|---|---|
| Blair, T; Webb, GA | 1 |
| Baron, BM; Dudley, MW; Kane, JM; Miller, FP; Sorensen, SM; Staeger, MA | 1 |
| Aoyama, T; Ichikawa, H; Suzuki, Y | 1 |
| Lüddens, H; Pritchett, DB; Seeburg, PH | 1 |
| Anderson, PS; Bock, MG; Chang, RS; DiPardo, RM; Evans, BE; Freidinger, RM; Lundell, GF; Rittle, KE; Veber, DF; Whitter, WL | 1 |
| Bock, MG; DiPardo, RM; Evans, BE; Freidinger, RM; Gould, NP; Homnick, CF; Lundell, GF; Rittle, KE; Veber, DF; Whitter, WL | 1 |
| Babbini, M; Barbaro, AM; Bartoletti, M; Biagi, GL; Borea, PA; Gaiardi, M; Guerra, MC | 1 |
| Johnston, GA; Maddalena, DJ | 1 |
| Karplus, M; So, SS | 1 |
| Da Settimo, A; Da Settimo, F; Gesi, M; Giannaccini, G; Greco, G; Lucacchini, A; Marini, AM; Martini, C; Novellino, E; Primofiore, G | 1 |
| Da Settimo, F; Gesi, M; Greco, G; La Motta, C; Marini, AM; Martini, C; Novellino, E; Primofiore, G; Taliani, S; Trincavelli, L | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Besnard, F; Cosimelli, B; Costa, B; Da Settimo, F; Greco, G; Martini, C; Montali, M; Novellino, E; Primofiore, G; Salerno, S; Taliani, S | 1 |
| Cleary, J; Glick, GD; Johnson, KM; Opipari, AW | 1 |
| Besnard, F; Calderone, V; Cosimelli, B; Da Settimo, F; Greco, G; La Motta, C; Marini, AM; Martini, C; Montali, M; Novellino, E; Patrizi, MP; Primofiore, G; Sergianni, V; Simorini, F; Taliani, S | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Cook, JM; Edwankar, CR; Edwankar, RV; Furtmüller, R; Huang, S; Jain, HD; Majumder, S; Murphree, L; Ramerstorfer, J; Rivas, FM; Roth, BL; Sankar, S; Sieghart, W; Stables, JP; Zhou, H | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Buttar, D; Colclough, N; Gerhardt, S; MacFaul, PA; Maskos, K; Phillips, SD; Plowright, A; Steinbacher, S; Steuber, H; Tam, K; Whittamore, P | 1 |
| Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC | 1 |
| Bertucci, C; Carocci, A; Carrieri, A; Catalano, A; Conte Camerino, D; Corbo, F; De Bellis, M; De Luca, A; Desaphy, JF; Fortugno, C; Franchini, C; Muraglia, M | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Baglini, E; Barresi, E; Robello, M; Salerno, S; Settimo, FD; Taliani, S | 1 |
| Markovich, VV; Ostrovskaia, RU | 1 |
| Bird, ED; Reisine, TD; Speth, RC; Wastek, GJ; Yamamura, HI | 1 |
| Frövig, AG; Mellgren, SI; Nyland, H | 1 |
| Snead, OC | 1 |
| Loiseau, P | 2 |
| Lison, MP; Speciali, GG | 1 |
| Palmer, GC | 1 |
| Jones, DJ; Medina, MA; Palmer, GC; Stavinoha, WB | 1 |
| Hebenstreit, G; Lechner, H | 1 |
| Chadwick, D; Jenner, P; Marsden, CD; Reynolds, EH | 1 |
| Perchalski, RJ; Wilder, BJ | 1 |
| Reith, H; Schäfer, H | 1 |
| Aicardi, J | 1 |
| Binder, H; Gerstenbrand, F; Hengl, W; Rumpl, E | 1 |
| Iffland, E; Lagenstein, I | 1 |
| Baraldi, M; Costa, E; Guidotti, A; Schwartz, JP | 1 |
| Ashton, D; Melis, W; Wauquier, A | 1 |
| Miyasaka, M | 1 |
| Fukuda, H; Kudo, Y; Ono, H; Tanaka, Y; Togari, A | 1 |
| Ikeda, S; Kato, H; Mori, T; Morizaki, I | 1 |
| Ataki, Y; Gomita, Y; Ueki, S; Yamada, K; Yoshimura, H | 1 |
| Westblom, U | 2 |
| Chou, DT; Wallenstein, MC; Wang, SC | 1 |
| Banerjee, U; Yeoh, PN | 1 |
| Chadwick, D; Gorrod, JW; Jenner, P; Marsden, CD; Reynolds, EH | 1 |
| Braestrup, C; Nielsen, M | 1 |
| Magnus, O; Van Huffelen, AC | 1 |
| Gastaut, H; Osuntokun, BO | 1 |
| Dam, M; Hvidberg, EF | 1 |
| Browne, TR | 1 |
| Hanifl, EJ; Wad, NT | 1 |
| Furukawa, T; Ono, N | 1 |
| Haefely, W; Pieri, L | 1 |
| Fukushima, H; Kitagawa, S; Tsuchiya, T | 1 |
| Danielson, MG; Fowler, GW; Julien, RM | 1 |
| Berman, W | 1 |
| Chou, DT; Wang, SC | 1 |
| Anlezark, G; Balzamo, E; Horton, RW; Meldrum, BS; Trimble, M | 1 |
| Bekersky, I; Brooks, MA; de Silva, JA; Puglisi, CV; Weinfeld, RE | 1 |
| Chen, BJ | 1 |
| Advenier, C; Candenas, ML; Devillier, P; Naline, E | 1 |
| Järvinen, A; Männistö, PT; Rägo, L | 1 |
| Furuie, MA; Hibino, S; Maruyama, T; Otagiri, M | 1 |
| De Sarro, A; De Sarro, GB; Gratteri, S; Juliano, M; Rotiroti, D; Sinopoli, S | 1 |
| Morgenstern, E; Voigt, JP | 1 |
| Almog, S; Ezra, D; Mordel, A; Tirosh, M; Winkler, E | 1 |
| Mattigk, G | 1 |
| Diana, G; Massotti, M | 1 |
| Georgiev, VP; Kambourova, TS; Lazarova, MB | 1 |
| al-Tikriti, MS; Baldwin, RM; Innis, RB; Johnson, EW; Laruelle, MA; Malison, RT; Seibyl, JP; Sybirska, EH; Zimmermann, RC; Zoghbi, SS | 1 |
| Järvinen, A; Männistö, PT; Paakkari, I | 1 |
| Kariya, T; Motohashi, N; Shioe, K | 1 |
| Blasquez, C; Braquet, P; Delbende, C; Jégou, S; Tranchand Bunel, D; Vaudry, H | 1 |
| Breimer, DD; de Boer, AG; van Hoogdalem, E | 1 |
| Keck, PE; Lawrence, JM; McElroy, SL | 1 |
| Andersen, KE; Braestrup, C; Knutsen, LJ; Nielsen, EB; Sonnewald, U; Suzdak, PD | 1 |
| De Luca, C; De Medici, D; Massotti, M | 1 |
| Lichtensteiger, W; Parmar, R; Ramseier, HR; Schlumpf, M | 1 |
| Advenier, C; Blanc, M; Devillier, P; Gnassounou, JP | 1 |
| Izquierdo, I; Medina, JH; Pereira, ME | 1 |
| Elgoyhen, AB; Kazanietz, MG | 1 |
| Connick, JH; Mally, J; Stone, TW | 1 |
| Wong, PT | 1 |
| Fukuda, T | 1 |
| Pranzatelli, MR | 1 |
| De Luca, C; Massotti, M; Mele, L | 1 |
| Graae, F | 1 |
| Deutsch, SI; Huntzinger, JA; Mastropaolo, J; Novitzki, MR; Rosse, RB | 1 |
| Hakeem, VF; Wallace, SJ | 1 |
| Baron, DH; Ciraulo, DA; Sands, BF; Shader, RI | 1 |
| Hishida, H | 1 |
| Haefely, W | 1 |
| Griffith, JA; Woolley, DE | 1 |
| Adler-Graschinsky, E; Elgoyhen, B | 1 |
| Kubo, H; Miura, H; Nishida, A; Nishikawa, T; Ohtani, H; Sudo, Y; Sunaoshi, W | 1 |
| Lichtensteiger, W; Ramseier, H; Schlumpf, M | 2 |
| Bachy, A; Cordeau, LR; Croizat, BP; Gros, F; Keane, PE; Larcher, JC; Le Marquer, FJ; Vayssiere, JL | 1 |
| Gorman, AM; O'Beirne, GB; Regan, CM; Williams, DC | 1 |
| Kellogg, CK; Miranda, RC; Wagner, JP | 1 |
| Klosterkötter, J; Penin, H | 1 |
| Gastfriend, DR; Rosenbaum, JF | 1 |
| Adler-Graschinsky, E; Elgoyhen, AB; Filinger, EJ | 1 |
| Balon, R; Pohl, R; Ramesh, C | 1 |
| Treiman, DM | 1 |
| Ahlemeyer, B; Krieglstein, J | 1 |
| Calandra, RS; Ritta, MN | 1 |
| Krishnamoorthy, MS; Paul, V | 1 |
| Diwan, BA; Henneman, JR; Klaunig, JE; Lubet, RA; Nims, RW; Rice, JM; Ward, JM; Weghorst, CM | 1 |
| Dobyns, WB | 1 |
| Chen, J; Cheng, GF; Jiang, ZH; Wang, LP; Zhou, TC | 1 |
| Sher, PK; Talwar, D | 1 |
| Hanada, S; Hashimoto, S; Tanaka, C; Taniyama, K | 1 |
| Vernay, A; Vu Duc, T | 1 |
| Rennert, H | 1 |
| Gross, RA; Macdonald, RL; Weddle, MG | 1 |
| Boespflug, O; Swaiman, KF | 1 |
| Albeck, JH | 1 |
| Concas, A; Morelli, M; Obata, T; Serra, M; Yamamura, HI | 1 |
| Altunkaya, D; Smith, RN | 1 |
| Capek, R; Davies, MF; Esplin, B | 1 |
| Cole, R; De Vellis, J; Noble, EP; Syapin, PJ | 1 |
| Fares, F; Gavish, M | 1 |
| Belin, C; Carriot, T; Dubroeucq, MC; Guérémy, C; Le Fur, G; Mestre, M; Renault, C; Uzan, A | 2 |
| Bryere, P; Naquet, R; Valin, A | 1 |
| Sieghart, W | 1 |
| Lenfant, M; Zavala, F | 1 |
| Medici, V | 1 |
| Keller, HP; Roth, F | 1 |
| Bentley, M; Feely, M; Gent, JP; Haigh, JR | 1 |
| Teo, WL; Wong, PT | 1 |
| Bülau, P; Fröscher, W; Kreiten, K; Schuchardt, V | 1 |
| Kunert-Radek, J; Pawlikowski, M; Radek, A; Stepien, H | 1 |
| Morrow, AL; Paul, SM | 1 |
| Vining, EP | 1 |
| Brown, JK; Livingston, JH | 1 |
| Brown, T; Fogel, R; Gaginella, T; Marshall, D; Michelson, G; Senler, T | 1 |
| Crawley, JN; Martin, JV; Mendelson, WB; Stivers, JA | 1 |
| Farrell, K | 1 |
| Marano, F; Miernik, A; Santa-Maria, A | 1 |
| Fukazawa, T; Hamada, T; Kase, M; Tashiro, K | 1 |
| Kuroda, Y; Shibasaki, H; Shin, T; Tomoda, H | 1 |
| Frey, HH; Löscher, W | 1 |
| Georgiev, VP; Petkov, VV | 2 |
| Herranz Fernández, JL | 1 |
| Bender, AS; Hertz, L | 1 |
| Beaumont, K; Fanestil, DD; Healy, DP | 1 |
| Fioretti, P; Galbani, P; Gambacciani, M; Melis, G; Ronca-Testoni, S | 1 |
| Anderson, RA; Mitchell, R | 1 |
| Caputti, E; Cardinali, DP; Lowenstein, PR; Rosenstein, R | 1 |
| Janicki, P; Szreniawski, Z | 1 |
| Miyoshi, K; Morita, Y; Shibagaki, N; Shinkuma, D | 1 |
| Georgiev, VP; Getova, D; Petkov, V; Petkov, VV | 1 |
| Annable, L; Chouinard, G; Fontaine, R; Labonte, A | 1 |
| Snell, CR; Snell, PH | 1 |
| Kobayashi, H; Saito, H; Sakai, T; Takeno, S | 1 |
| Etienne, P; Lal, S; Nair, NP; Wood, PL | 1 |
| Spector, S; Taniguchi, T; Wang, JK | 1 |
| Fehske, KJ; Muller, WE | 1 |
| Benavides, J; Dubroeucq, MC; Flamier, A; Guérémy, C; Imbault, F; Le Fur, G; Perrier, ML; Renault, C; Uzan, A; Vaucher, N | 1 |
| Benavides, J; Dubroeucq, MC; Guérémy, C; Guilloux, F; Le Fur, G; Renault, C; Rufat, P; Uzan, A | 1 |
| Feil, P; Scharf, MB | 1 |
| Del Zompo, M; Post, RM; Tallman, JF | 1 |
| Sher, PK | 1 |
| Benavides, J; Dubroeucq, MC; Flamier, A; Guérémy, C; Le Fur, G; Perrier, ML; Renault, C; Uzan, A; Vaucher, N | 1 |
| Casida, JE; Gammon, D | 1 |
| DeLorenzo, RJ; Taft, WC | 1 |
| Camoratto, AM; Grandison, L | 1 |
| Matlib, MA; Schwartz, A | 1 |
| Bleck, TP | 1 |
| Post, RM; Uhde, TW | 1 |
| Battistin, L; Berlese, G; Roman, G; Varotto, M | 1 |
| Khalansky, AS; Kondakova, LI; Zlobina, GP | 1 |
| Averill, DR; Fox, JG; Hallett, M; Schunk, K | 1 |
| Ebel, C; Mallorga, P; Roth-Schechter, BF | 1 |
| Danilova, EI; Grafova, VN; Kryshanovskiĭ, GN | 1 |
| Machen, VL; Sher, PK | 1 |
| Carter, RB; Leander, JD | 2 |
| Franco-Morselli, R; Morselli, PL | 1 |
| Fröscher, W | 1 |
| Bittencourt, PR; Richens, A | 1 |
| Scollo-Lavizzari, G | 1 |
| Dixon, R | 1 |
| Bureau, M; Daniele, O; Dravet, C; Michelucci, R; Roger, J; Tassinari, CA | 1 |
| Allievi, E; Banfi, S; Fonio, W; Raimondo, S | 1 |
| Avanzini, G; Franceschetti, S; Lombardi, B; Passerini, A | 1 |
| Hertz, MM; Paulson, OB | 1 |
| Györy, A; Hertz, MM; Paulson, OB | 1 |
| Bøjholm, S; Flachs, H; Paulson, OB | 1 |
| Di Chiara, G; Fossarello, M; Imperato, A; Morelli, M; Porceddu, ML | 1 |
| Battistin, L; Roman, G; Varotto, M | 1 |
| Inami, M; Muraoka, H; Murasaki, M; Okamoto, K; Sumiyoshi, A; Takahashi, A; Yamazumi, S | 1 |
| Congdon, PJ; Forsythe, WI | 1 |
| Barker, JL; Huang, A; Moncada, V; Paul, SM; Skolnick, P | 1 |
| Hertz, L; Mukerji, S | 1 |
| Ekström, P; Grossmann, E; Meissl, H; Yáñez, J | 1 |
| Ator, NA; Sannerud, CA | 1 |
| Elías, MM; Monasterolo, LA; Ochoa, JE; Trumper, L | 1 |
| Breschi, MC; Cristofani, R; Giannaccini, G; Lucacchini, A; Martini, C; Martinotti, E; Scatizzi, R | 1 |
| Needleman, SB; Porvaznik, M | 1 |
| Huang, ZC | 1 |
| Gajewska, M; Goldnik, A; Jaworska, M | 1 |
| Korinthenberg, R | 1 |
| Huang, ZC; Shen, DL | 1 |
| Ryu, H; Uemura, K; Yokoyama, T | 1 |
| Chiu, TH; Li, M; Rosenberg, HC | 1 |
| Yasuda, K | 3 |
| Kwan, YW; Ngan, MP; Yiu, MK | 1 |
| George, B; Kulkarni, SK | 1 |
| Misawa, S; Tanaka, E; Terada, M; Wakasugi, C | 1 |
| Mazurek, MF; Rosebush, PI | 1 |
| Hansen, HC; Jackson, HC; Judge, ME; Klitgaard, H; Kristiansen, M; Suzdak, PD; Swedberg, MD | 1 |
| Møller, AR; Szczepaniak, WS | 1 |
| Aguglia, U; de Sarro, A; De Sarro, G; Di Paola, ED | 1 |
| Fink, H; Morgenstern, E; Voigt, JP | 1 |
| Ebert, U; Hönack, D; Löscher, W; Rundfeldt, C | 1 |
| Burke, AL | 1 |
| Dragnev, KH; Jones, CR; Lubet, RA; Nims, RW; Prough, RA; Stockus, DL; Thomas, PE | 1 |
| Bessler, H; Caspi, B; Gavish, M; Rehavi, M; Weizman, A | 1 |
| Gomita, Y; Kawasaki, H; Suemaru, K | 1 |
| Butterworth, RF; Rao, VL | 1 |
| Boothe, DM | 1 |
| Caldiroli, E; Cattaneo, S; Cosentino, M; Di Grazia, L; Frigo, G; Lecchini, S; Marino, F | 1 |
| Biggio, G; Concas, A; Marino, G; Minei, R; Mostallino, MC; Pierobon, P; Porcu, P | 1 |
| Ali, HM; Azzam, RM; Notarianni, LJ | 1 |
| Møller, MB | 1 |
| Cassim, F; Destée, A; Guieu, JD; Mastain, B | 1 |
| Beery, E; Brenner, S; Gavish, M; Landau, M; Landau, O; Nordenberg, J; Wasseman, L; Weizman, A; Zoref-Shani, E | 1 |
| Blanc, F; Butterworth, RF; Fabbro-Peray, P; Lavoie, J; Layrargues, GP; Mousseau, DD; Perney, P | 1 |
| Chao, CC; Gekker, G; Hu, S; Lokensgard, JR; Peterson, PK | 1 |
| Kawaguchi, M; Okubo, M | 2 |
| Bender, AS; Norenberg, MD | 1 |
| Leeuwin, RS; van Wilgenburg, H; Zeegers, A | 1 |
| Kizaki, H; Onishi, Y; Sato, Y; Tanimoto, Y | 1 |
| Bechgaard, E; Gizurarson, S; Greenough, RJ; Hjortkjaer, RK; McDonald, P; Suzdak, C | 1 |
| Fornai, F; Gesi, M; Lenzi, P; Natale, G; Paparelli, A; Pellegrini, A; Riva, A; Soldani, P | 1 |
| Contarino, A; Giusti, P; Lipartiti, M; Natolino, F; Zanotti, A | 1 |
| Bono, F; Herbert, JM; Lamarche, I; Le Fur, G; Prabonnaud, V | 1 |
| Choi, YM; Gorukanti, S; Kim, KH; Li, L | 1 |
| Charney, DA; Gill, KJ; Paraherakis, AM | 1 |
| Czechowska, G; Kleinrok, Z; Rajtar, G; Zółkowska, D | 1 |
| Li, M; Rosenberg, HC; Szabo, A | 1 |
| Arakawa, T; Inobe, J; Kumamoto, T; Mori, T; Tsuda, T | 1 |
| Smith, MA; Stoops, WW | 1 |
| Barsaoui, S; Essoussi, AS; Oubich, F; Selmi, H; Tabarki, B; Yacoub, M | 1 |
| Gekker, G; Hegg, CC; Hu, S; Lokensgard, JR; Peterson, PK; Thayer, SA | 1 |
| Kleinrok, Z; Rajtar, G; Zółkowska, D | 1 |
| Elías, MM; Monasterolo, LA; Trumper, L | 1 |
| Barzegar-Jalali, M; Ghafourian, T; Nokhodchi, A; Shokri, J | 1 |
| Kachi, T | 1 |
| Riedl, B | 1 |
| Klitgaard, H; Margineanu, DG | 1 |
| Barsoum, BN; Izake, EL; Salem, AA | 1 |
| Craig, CK; French, AM; Smith, MA | 1 |
| Hendset, M; Island, TK; Lunder, N; Refsum, H | 1 |
| Bloem, BR; Renier, WO; Voermans, NC; Zwarts, MJ | 1 |
| Polesin, A; Stern, M | 1 |
| Dickson, SJ; Irving, RC | 1 |
| von Wrede, R | 1 |
| Lopes, DV; Mendonça-Silva, DL; Noël, F; Thibaut, JP | 1 |
| Kulvanich, P; Ongpipattanakul, B; Sila-on, W; Vardhanabhuti, N | 1 |
| Dervaux, A; Kanit, M; Laqueille, X; Launay, C | 1 |
| Buckingham, SD; Higashino, Y; Sattelle, DB | 1 |
| Barker, KE; Batstone, MD; Savage, NW | 1 |
| Chou, D; Duley, L; Henderson-Smart, DJ | 1 |
| Acree, WE; Jouyban, A; Panahi-Azar, V; Shayanfar, A; Soleymani, J; York, P; Yousefi, BH | 1 |
| Abreu, MH; Firmino, KF; Magalhães, SM; Perini, E | 1 |
| Frauger, E; Lapeyre-Mestre, M; Micallef, J; Natali, F; Nordmann, S; Pauly, V; Pourcel, L; Pradel, V; Sciortino, V; Thirion, X | 1 |
| Krzek, J; Maślanka, A; Szlósarczyk, M; Wach, K; Żmudzki, P | 1 |
| Alijanpour, SO; Chaichi, MJ | 1 |
| Bykov, VN; Chepur, SV; Nikiforov, AS; Subbotina, SN; Yudin, MA | 1 |
| Lubszky, S; Reinhart, WH; Schulzki, T; Thöny, S | 1 |
| de Bortoli, VC; Lopes, MA; Pobbe, RL; Vasconcelos, AT; Yamashita, PS; Zangrossi, H | 1 |
| Cui, YL; He, X; Liu, J; Shan, WC; Wang, JP; Zhang, L | 1 |
| Christophersen, AS; Enger, A; Nordal, K; Vindenes, V; Øiestad, EL | 1 |
| Araujo Cordeiro, KC; Costa, MB; da Silva e Sousa, DB; de Melo Souza, PL; de Oliveira, V; de Paula, NC; Noël, F; Nogueira, DF | 1 |
| Hsu, MH; Huang, CW; Iqbal, U; Jian, WS; Li, YJ; Nguyen, PA; Syed-Abdul, S; Yang, HC; Yen, Y | 1 |
| Gong, L; Guo, C; Jiang, S; Shi, F; Tan, H | 1 |
| Bjørner, T; Skomedal, T; Tvete, IF | 1 |
| Elhenawee, M; Hashem, H; Ibrahim, AE; Saleh, H | 1 |
| Hide, M; Kamegashira, A; Okamoto, M; Takahagi, S; Yanase, Y | 1 |
| Bauerfeldt, GF; de Araujo, FG; Marques, M; Martins, EM | 1 |
| Payne, E; Wallace, A; Wirrell, E | 1 |
| Chéron, G; Heilbronner, C; Hubert, P; Le Coz, J; Nabbout, R; Oualha, M; Patteau, G; Renolleau, S | 1 |
| Chen, S; Shen, D; Zhou, H | 1 |
| Hughes, DA | 1 |
| Falcon, M; Fernadez-Lopez, L; Luna, A; Mancini, R; Pellegrini, M; Rotolo, M | 1 |
| Amagai, M; Fukasawa, T; Takahashi, H; Takahashi, K; Tanemura, N; Urushihara, H | 1 |
| García-Peñas, JJ; Gil Nagel-Rein, A; Sánchez-Carpintero, R; Villanueva-Haba, V | 1 |
| Cao, Y; Lian, J; Ma, Y; Muheyati, A; Su, R; Wang, N; Yu, G; Yuan, S; Zhang, S | 1 |
| Barkholtz, H; Miles, A; Pieters, R; Sanders, T; Savage, T | 1 |
| Fang, L; Tong, X; Wu, X; Xu, Y; Zhou, X | 1 |
| Beuchat, I; Gelhard, S; Kay, L; Kienitz, R; Lucaciu, A; Mann, C; Rosenow, F; Schäfer, JH; Schubert-Bast, S; Siebenbrodt, K; Strzelczyk, A; von Brauchitsch, S; Willems, LM; Zöllner, JP | 1 |
| Adhikari, S; Barron, LP; Bhatnagar, A; Bowes, DA; Coronado-Apodaca, KG; Driver, EM; Halden, RU; Kumar, R; Martínez-Ruiz, M; McCall, KL; Melchor-Martínez, EM; Ng, KT; Oyervides-Muñoz, MA; Parra-Saldivar, R; Piper, BJ; Smith, T; Sosa-Hernandez, JE | 1 |
| Calegari, L; da Rosa, TF; de Paula, BR; Foletto, VS; Franco, LN; Fuchs, LB; Hörner, R; Serafin, MB | 1 |
| Eshaghi Malekshah, R; Ganjali Koli, M; Hajiabadi, H | 1 |
| Hume, AL; Lawal, OD; Meador, KJ; Wen, X | 1 |
| Barbui, C; Bighelli, I; Caldwell, DM; Cipriani, A; Davies, SJ; Dawson, S; Dias, S; Furukawa, TA; Guaiana, G; Imai, H; Koesters, M; Meader, N; Pompoli, A; Robertson, L; Tajika, A | 1 |
32 review(s) available for diazepam and clonazepam
| Article | Year |
|---|---|
Neural networks applied to quantitative structure-activity relationship analysis.
Topics: Animals; Azirines; Benzodiazepines; Carbazilquinone; Nerve Net; Nervous System; Regression Analysis; Structure-Activity Relationship | 1990 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
The Alpha Keto Amide Moiety as a Privileged Motif in Medicinal Chemistry: Current Insights and Emerging Opportunities.
Topics: Amides; Animals; Cell Line, Tumor; Chemistry, Pharmaceutical; Humans; Ketones | 2021 |
[Antiepileptics during pregnancy and lactation. Pharmacokinetic data].
Topics: Anticonvulsants; Bromides; Carbamazepine; Clonazepam; Diazepam; Ethosuximide; Female; Fetus; Humans; Kinetics; Lactation; Maternal-Fetal Exchange; Nitrazepam; Phenobarbital; Phenytoin; Pregnancy; Primidone; Valproic Acid | 1979 |
Clinical pharmacokinetics of anticonvulsants.
Topics: Administration, Oral; Adult; Aged; Aging; Animals; Anticonvulsants; Carbamazepine; Child; Clonazepam; Diazepam; Drug Interactions; Ethosuximide; Female; Humans; Hydantoins; Infant, Newborn; Injections, Intramuscular; Injections, Intravenous; Intestinal Absorption; Kidney Diseases; Kinetics; Liver Diseases; Milk; Molecular Biology; Phenobarbital; Phenytoin; Pregnancy; Primidone; Valproic Acid | 1976 |
Clonazepam. A review of a new anticonvulsant drug.
Topics: Adult; Benzodiazepinones; Brain; Chemical Phenomena; Chemistry; Child; Clonazepam; Diazepam; Drug Tolerance; Electroencephalography; Enzyme Induction; Epilepsies, Partial; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Fetus; Humans; Light; Myoclonus; Spasms, Infantile; Substance-Related Disorders | 1976 |
[Current therapy of febrile convulsions].
Topics: Adolescent; Adult; Child; Child, Preschool; Clonazepam; Diazepam; Humans; Infant; Seizures, Febrile | 1992 |
Pharmacokinetics of rectal drug administration, Part I. General considerations and clinical applications of centrally acting drugs.
Topics: Administration, Rectal; Antiemetics; Atropine; Carbamazepine; Clonazepam; Delayed-Action Preparations; Diazepam; Flunitrazepam; Humans; Hydromorphone; Intestinal Absorption; Methadone; Methohexital; Midazolam; Morphine; Pharmacokinetics; Phenobarbital; Valproic Acid | 1991 |
High anxiety in children.
Topics: Adult; Age Factors; Anxiety Disorders; Child; Clinical Trials as Topic; Clonazepam; Diazepam; Humans | 1990 |
[Epileptic psychoses and their drug treatment].
Topics: Anticonvulsants; Antipsychotic Agents; Clonazepam; Diazepam; Epilepsy; Humans; Neurocognitive Disorders | 1989 |
Pharmacokinetics and clinical use of benzodiazepines in the management of status epilepticus.
Topics: Benzodiazepines; Chemical Phenomena; Chemistry; Clonazepam; Diazepam; Humans; Lorazepam; Status Epilepticus | 1989 |
Withdrawal and detoxification from benzodiazepine dependence: a potential role for clonazepam.
Topics: Adolescent; Adult; Aged; Alprazolam; Anti-Anxiety Agents; Clonazepam; Diazepam; Drug Tolerance; Humans; Male; Middle Aged; Substance Withdrawal Syndrome; Substance-Related Disorders; Triazolam | 1987 |
Use of barbiturates and benzodiazepines in treatment of epilepsy.
Topics: Adult; Barbiturates; Benzodiazepines; Child; Clonazepam; Clorazepate Dipotassium; Diazepam; Epilepsy; Humans; Infant; Infant, Newborn; Lorazepam; Phenobarbital; Primidone | 1986 |
Pharmacokinetics of anti-epileptic drugs in the dog: a review.
Topics: Animals; Anticonvulsants; Blood Proteins; Carbamazepine; Clonazepam; Diazepam; Dog Diseases; Dogs; Epilepsy; Ethosuximide; Kinetics; Phenobarbital; Phenytoin; Primidone; Species Specificity; Trimethadione; Valproic Acid | 1985 |
[Benzodiazepines in the treatment of epilepsy].
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Child, Preschool; Clobazam; Clonazepam; Clorazepate Dipotassium; Diazepam; Epilepsy; Epilepsy, Temporal Lobe; Humans; Injections, Intravenous; Nitrazepam; Status Epilepticus; Suppositories | 1983 |
Therapy for status epilepticus.
Topics: Acetazolamide; Anesthesia; Anticonvulsants; Barbiturates; Chlormethiazole; Clonazepam; Diazepam; Ethosuximide; Humans; Lidocaine; Lorazepam; Paraldehyde; Phenobarbital; Phenytoin; Status Epilepticus; Valproic Acid | 1983 |
Treatment of mood disorders with antiepileptic medications: clinical and theoretical implications.
Topics: Anticonvulsants; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Clonazepam; Depressive Disorder; Diazepam; Double-Blind Method; Humans; Phenytoin; Valproic Acid | 1983 |
Clinical pharmacokinetics of antiepileptic drugs in adults.
Topics: Adult; Aging; Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Disease; Ethosuximide; Female; Humans; Kinetics; Phenobarbital; Phenytoin; Pregnancy; Primidone; Saliva; Valproic Acid | 1980 |
Pharmacological principles in the long-term treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Epilepsy; Ethosuximide; Humans; Kinetics; Long-Term Care; Phenobarbital; Phenytoin; Primidone; Succinimides; Valproic Acid | 1981 |
[Athetosis].
Topics: Athetosis; Brain Diseases; Clonazepam; Diazepam; Humans; Metabolic Diseases | 1993 |
[Clonazepam, nitrazepam, diazepam].
Topics: Adult; Anticonvulsants; Child; Clonazepam; Diazepam; Drug Monitoring; Humans; Nitrazepam | 1995 |
Palliative care: an update on "terminal restlessness".
Topics: Anti-Anxiety Agents; Anticonvulsants; Antipsychotic Agents; Clonazepam; Delirium; Diazepam; Humans; Midazolam; Palliative Care; Phenobarbital; Psychomotor Agitation; Terminal Care | 1997 |
Anticonvulsant therapy in small animals.
Topics: Acetates; Amines; Animals; Anticonvulsants; Bromides; Clonazepam; Clorazepate Dipotassium; Cyclohexanecarboxylic Acids; Diazepam; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Mephenytoin; Pentobarbital; Phenobarbital; Phenylcarbamates; Phenytoin; Primidone; Propylene Glycols; Seizures; Valproic Acid | 1998 |
Benzodiazepines, glia, and HIV-1 neuropathogenesis.
Topics: AIDS Dementia Complex; Anti-HIV Agents; Benzodiazepines; Clonazepam; Diazepam; Drug Design; Gene Expression Regulation, Viral; HIV Core Protein p24; HIV-1; Humans; Lipopolysaccharides; Microglia; Nerve Degeneration; NF-kappa B; Transcription, Genetic; Tumor Necrosis Factor-alpha; Virus Replication | 1998 |
[Benzodiazepine (clonazepam, nitrazepam, diazepam)].
Topics: Adult; Anticonvulsants; Child; Clonazepam; Diazepam; Humans; Nitrazepam | 1999 |
[Medical treatment of dystonia].
Topics: Cholinergic Antagonists; Clonazepam; Diazepam; Dopamine Antagonists; Dystonia; Humans; Levodopa; Torticollis; Trihexyphenidyl | 2001 |
[Benzodiazepine (clonazepam, nitrazepam, diazepam)].
Topics: Aging; Anticonvulsants; Biomarkers; Chromatography, Gas; Chromatography, High Pressure Liquid; Clonazepam; Diazepam; Drug Interactions; Drug Monitoring; Food-Drug Interactions; Humans; Nitrazepam; Reference Values; Specimen Handling; Treatment Refusal | 2004 |
[Abuse of alcohol and benzodiazepine during substitution therapy in heroin addicts: a review of the literature].
Topics: Adolescent; Adult; Alcoholism; Benzodiazepines; Buprenorphine; Clonazepam; Clorazepate Dipotassium; Comorbidity; Controlled Clinical Trials as Topic; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Ethanol; Euphoria; Flunitrazepam; Heroin Dependence; Humans; Metabolic Clearance Rate; Methadone; Narcotics; Substance-Related Disorders; Young Adult | 2009 |
Magnesium sulphate versus phenytoin for eclampsia.
Topics: Anticonvulsants; Clonazepam; Diazepam; Drug Combinations; Eclampsia; Female; Humans; Magnesium Sulfate; Nifedipine; Phenytoin; Pregnancy; Randomized Controlled Trials as Topic | 2010 |
Cannabidiol for the treatment of Lennox-Gastaut syndrome and Dravet syndrome: experts' recommendations for its use in clinical practice in Spain.
Topics: Anticonvulsants; Cannabidiol; Clobazam; Clonazepam; Diazepam; Dioxolanes; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Epilepsies, Myoclonic; Humans; Lennox Gastaut Syndrome; Phenobarbital; Practice Guidelines as Topic; Pyrrolidinones; Spain; Triazoles; Valproic Acid | 2021 |
Benzodiazepines in the Management of Seizures and Status Epilepticus: A Review of Routes of Delivery, Pharmacokinetics, Efficacy, and Tolerability.
Topics: Anticonvulsants; Benzodiazepines; Clonazepam; Diazepam; gamma-Aminobutyric Acid; Humans; Lorazepam; Midazolam; Seizures; Status Epilepticus | 2022 |
Pharmacological treatments in panic disorder in adults: a network meta-analysis.
Topics: Adult; Alprazolam; Antidepressive Agents; Antidepressive Agents, Tricyclic; Benzodiazepines; Clomipramine; Clonazepam; Desipramine; Diazepam; Fluoxetine; Humans; Network Meta-Analysis; Panic Disorder; Paroxetine; Reboxetine; Selective Serotonin Reuptake Inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors; Venlafaxine Hydrochloride | 2023 |
7 trial(s) available for diazepam and clonazepam
| Article | Year |
|---|---|
[Treatment of status epilepticus with clonazepam].
Topics: Benzodiazepinones; Clinical Trials as Topic; Clonazepam; Diazepam; Drug Evaluation; Humans; Phenobarbital; Phenytoin; Status Epilepticus | 1976 |
High anxiety in children.
Topics: Adult; Age Factors; Anxiety Disorders; Child; Clinical Trials as Topic; Clonazepam; Diazepam; Humans | 1990 |
[Prospective randomized study of the effectiveness of clonazepam and diazepam in petit mal status].
Topics: Adolescent; Adult; Aged; Child; Clonazepam; Diazepam; Electroencephalography; Epilepsy, Absence; Evoked Potentials; Female; Humans; Male; Middle Aged; Prospective Studies; Random Allocation | 1986 |
Non-convulsive status epilepticus resistant to benzodiazepines.
Topics: Adolescent; Benzodiazepines; Child; Child, Preschool; Clinical Trials as Topic; Clonazepam; Diazepam; Drug Resistance; Electroencephalography; Female; Humans; Male; Status Epilepticus | 1987 |
New concepts in benzodiazepine therapy: rebound anxiety and new indications for the more potent benzodiazepines.
Topics: Alprazolam; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Bipolar Disorder; Bromazepam; Clinical Trials as Topic; Clonazepam; Diazepam; Humans; Panic; Receptors, Cell Surface; Receptors, GABA-A; Recurrence; Substance Withdrawal Syndrome | 1983 |
Treatment of mood disorders with antiepileptic medications: clinical and theoretical implications.
Topics: Anticonvulsants; Bipolar Disorder; Carbamazepine; Clinical Trials as Topic; Clonazepam; Depressive Disorder; Diazepam; Double-Blind Method; Humans; Phenytoin; Valproic Acid | 1983 |
Clinical efficacy of clonazepam in the treatment of status epilepticus.
Topics: Anticonvulsants; Clonazepam; Diazepam; Humans; Quality of Life; Status Epilepticus; Treatment Outcome | 2022 |
278 other study(ies) available for diazepam and clonazepam
| Article | Year |
|---|---|
Electronic factors in the structure-activity relationship of some 1,4-benzodiazepin-2-ones.
Topics: Benzodiazepinones; Electrochemistry; Structure-Activity Relationship | 1977 |
2,4-Dihydro-3H-1,2,4-triazol-3-ones as anticonvulsant agents.
Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry, Physical; Gerbillinae; Hippocampus; Hypoxia; Male; Mice; Neurons; Phencyclidine; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Triazoles | 1990 |
Type I and type II GABAA-benzodiazepine receptors produced in transfected cells.
Topics: Cell Line; Diazepam; Flumazenil; Flunitrazepam; Humans; Molecular Weight; Pyridazines; Receptors, GABA-A; Recombinant Proteins; Transfection | 1989 |
Methods for drug discovery: development of potent, selective, orally effective cholecystokinin antagonists.
Topics: Administration, Oral; Animals; Benzodiazepines; Chemical Phenomena; Chemistry; Cholecystokinin; Drug Design; Mice; Receptors, Cholecystokinin; Receptors, GABA-A; Structure-Activity Relationship | 1988 |
Design of nonpeptidal ligands for a peptide receptor: cholecystokinin antagonists.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Cholecystokinin; Guinea Pigs; Ligands; Rats; Receptors, Cholecystokinin; Receptors, GABA-A; Structure-Activity Relationship | 1987 |
Rm values and structure-activity relationship of benzodiazepines.
Topics: Animals; Benzodiazepines; Chromatography, Thin Layer; Conflict, Psychological; Exploratory Behavior; Models, Biological; Rats; Solubility; Structure-Activity Relationship | 1980 |
Prediction of receptor properties and binding affinity of ligands to benzodiazepine/GABAA receptors using artificial neural networks.
Topics: Binding Sites; Ligands; Neural Networks, Computer; Predictive Value of Tests; Receptors, GABA-A; Structure-Activity Relationship | 1995 |
Genetic neural networks for quantitative structure-activity relationships: improvements and application of benzodiazepine affinity for benzodiazepine/GABAA receptors.
Topics: Algorithms; Benzodiazepines; Models, Genetic; Nerve Net; Protein Binding; Receptors, GABA-A; Structure-Activity Relationship | 1996 |
N'-Phenylindol-3-ylglyoxylohydrazide derivatives: synthesis, structure-activity relationships, molecular modeling studies, and pharmacological action on brain benzodiazepine receptors.
Topics: Animals; Anticonvulsants; Binding, Competitive; Brain; Cattle; Cerebral Cortex; Convulsants; Diazepam; Flumazenil; GABA Modulators; Glyoxylates; Hydrazines; In Vitro Techniques; Indoles; Ligands; Mice; Models, Molecular; Molecular Conformation; Receptors, GABA-A; Seizures; Structure-Activity Relationship | 1998 |
3-Aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-ones: tricyclic heteroaromatic derivatives as a new class of benzodiazepine receptor ligands.
Topics: Animals; Anticonvulsants; Benzimidazoles; Brain; Cattle; Convulsants; Diazepam; Flumazenil; GABA Modulators; In Vitro Techniques; Ligands; Membranes; Mice; Models, Molecular; Radioligand Assay; Receptors, GABA-A | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
High affinity central benzodiazepine receptor ligands: synthesis and biological evaluation of a series of phenyltriazolobenzotriazindione derivatives.
Topics: Animals; Binding, Competitive; Brain; Cattle; Cell Line; Chlorides; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Humans; In Vitro Techniques; Models, Molecular; Protein Isoforms; Radioligand Assay; Rats; Recombinant Proteins; Structure-Activity Relationship; Triazines; Triazoles | 2005 |
Inhibition of the mitochondrial F1F0-ATPase by ligands of the peripheral benzodiazepine receptor.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Apoptosis; Benzodiazepines; Cell Line, Tumor; Cell Proliferation; GABA-A Receptor Antagonists; Humans; Hydrolysis; Isoquinolines; Kinetics; Ligands; Mitochondria; Proton-Translocating ATPases; Structure-Activity Relationship | 2007 |
Novel N-substituted indol-3-ylglyoxylamides probing the LDi and L1/L2 lipophilic regions of the benzodiazepine receptor site in search for subtype-selective ligands.
Topics: Amides; Animals; Cattle; Cell Line; Cerebral Cortex; GABA-A Receptor Agonists; Glyoxylates; Hypnotics and Sedatives; In Vitro Techniques; Indoles; Ligands; Male; Mice; Mice, Inbred BALB C; Molecular Conformation; Motor Activity; Radioligand Assay; Rats; Structure-Activity Relationship | 2007 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Antiseizure activity of novel gamma-aminobutyric acid (A) receptor subtype-selective benzodiazepine analogues in mice and rat models.
Topics: Animals; Anticonvulsants; Benzodiazepines; Convulsants; Hippocampus; Kindling, Neurologic; Ligands; Mice; Pentylenetetrazole; Rats; Receptors, GABA-A; Seizures; Structure-Activity Relationship | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions.
Topics: Binding Sites; Crystallography, X-Ray; Drug Interactions; Humans; Pharmaceutical Preparations; Protein Binding; Protein Structure, Tertiary; Serum Albumin; Spectrometry, Fluorescence | 2010 |
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility | 2010 |
N-aryl-2,6-dimethylbenzamides, a new generation of tocainide analogues as blockers of skeletal muscle voltage-gated sodium channels.
Topics: Animals; Anti-Arrhythmia Agents; Chromatography, Affinity; Chromatography, High Pressure Liquid; Humans; Models, Molecular; Muscle, Skeletal; Patch-Clamp Techniques; Protein Binding; Quantitative Structure-Activity Relationship; Rats; Serum Albumin; Sodium Channels; Structure-Activity Relationship; Tocainide; Voltage-Gated Sodium Channel Blockers | 2014 |
[Inhibitory processes in the cerebral cortex and the anticonvulsive action of benzodiazepine derivatives].
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Brain; Cats; Cerebral Cortex; Clonazepam; Diazepam; Electrophysiology; gamma-Aminobutyric Acid; Lorazepam; Medazepam; Neural Inhibition; Phenobarbital; Phenytoin; Seizures; Semicarbazides | 1977 |
Alterations in the benzodiazepine receptor of Huntington's diseased human brain.
Topics: Aged; Anti-Anxiety Agents; Brain; Cerebellum; Clonazepam; Diazepam; Flunitrazepam; Frontal Lobe; Humans; Huntington Disease; Middle Aged; Putamen; Receptors, Drug | 1979 |
Stiff-man syndrome with central and peripheral nervous manifestations.
Topics: Clonazepam; Diazepam; Electromyography; Humans; Male; Middle Aged; Muscle Rigidity; Muscles; NADH, NADPH Oxidoreductases; Phenytoin; Syndrome | 1978 |
Gamma hydroxybutyrate in the monkey. III. Effect of intravenous anticonvulsant drugs.
Topics: Animals; Anticonvulsants; Behavior, Animal; Clonazepam; Diazepam; Electroencephalography; Ethosuximide; Haplorhini; Hydroxybutyrates; Infusions, Parenteral; Macaca mulatta; Phenobarbital; Seizures | 1978 |
[Antiepileptics used currently].
Topics: Anticonvulsants; Barbiturates; Carbamazepine; Clonazepam; Diazepam; Humans; Hydantoins; Primidone; Succinimides; Valproic Acid | 1979 |
[Effect of drugs on electroclinical types of epileptic seizures in Lennox-Gastaut syndrome].
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Child; Child, Preschool; Clonazepam; Diazepam; Electroencephalography; Epilepsy; Female; Humans; Infant; Male; Nitrazepam; Phenobarbital; Phenytoin; Primidone; Seizures; Spasms, Infantile; Syndrome | 1977 |
Interactions of antiepileptic drugs on adenylate cyclase and phosphodiesterases in rat and mouse cerebrum.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Clonazepam; Cyclic AMP; Diazepam; Dopamine; Male; Norepinephrine; Phenobarbital; Phenytoin; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Rats | 1979 |
Anticonvulsant drug actions on in vitro and in vivo levels of cyclic AMP in the mouse brain.
Topics: Adenosine; Animals; Anticonvulsants; Brain; Carbamazepine; Cerebellum; Cerebral Cortex; Clonazepam; Culture Techniques; Cyclic AMP; Diazepam; Male; Mice; Norepinephrine; Ouabain; Pentylenetetrazole; Phenobarbital; Phenytoin; Potassium; Premedication; Seizures | 1979 |
[Drug therapy of epilepsy].
Topics: Anticonvulsants; Carbamazepine; Chlordiazepoxide; Clonazepam; Diazepam; Electroencephalography; Epilepsy; Humans; Hydantoins; Mephobarbital; Nitrazepam; Primidone; Succinimides; Thiazines; Time Factors | 1975 |
Altered 5-HT metabolism with clonazepam, diazepam and diphenylhydantoin.
Topics: Animals; Benzodiazepinones; Brain; Clonazepam; Diazepam; Humans; Hydroxyindoleacetic Acid; Male; Mice; Myoclonus; Neurons; Phenytoin; Serotonin | 1975 |
Determination of benzodiazepine anticonvulsants in plasma by high-performance liquid chromatography.
Topics: Benzodiazepinones; Chromatography, High Pressure Liquid; Clonazepam; Diazepam; Humans; Nordazepam; Spectrophotometry, Ultraviolet | 1978 |
Drugs for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Status Epilepticus; Valproic Acid | 1979 |
Recent advances in drug therapy of some forms of childhood epilepsy.
Topics: Anticonvulsants; Carbamazepine; Child; Clonazepam; Diazepam; Drug Therapy, Combination; Epilepsy; Humans; Valproic Acid | 1979 |
[Electrophysiogical and neuropharmacological studies in a patient with progressive myoclonus-epilepsy (author's transl)].
Topics: Adult; Anticonvulsants; Brain; Clonazepam; Diazepam; Electroencephalography; Epilepsies, Myoclonic; Female; Humans; Levodopa; Phenobarbital; Taurine | 1977 |
[Intraveneous therapy of petit mal status with diazepame and clonazepame (author's transl)].
Topics: Anticonvulsants; Benzodiazepinones; Child; Clonazepam; Diazepam; Electroencephalography; Female; Humans; Injections, Intravenous; Male; Status Epilepticus | 1977 |
GABA receptors in clonal cell lines: a model for study of benzodiazepine action at molecular level.
Topics: Animals; Benzodiazepines; Brain; Cell Line; Clonazepam; Clone Cells; Diazepam; Flunitrazepam; gamma-Aminobutyric Acid; Membrane Proteins; Mice; Nerve Tissue Proteins; Rats; Receptors, Drug | 1979 |
Behavioral analysis of amygdaloid kindling in beagle dogs and the effects of clonazepam, diazepam, phenobarbital, diphenylhydantoin, and flunarizine on seizure manifestation.
Topics: Amygdala; Animals; Anticonvulsants; Behavior, Animal; Brain; Clonazepam; Diazepam; Dogs; Electric Stimulation; Phenobarbital; Phenytoin; Piperazines; Seizures; Status Epilepticus | 1979 |
Status epilepticus: discussion from experience in adult cases.
Topics: Adolescent; Adult; Clonazepam; Diazepam; Female; Humans; Phenytoin; Status Epilepticus | 1979 |
[Pharmacological study on 5-(o-chlorophenyl)-1-methyl-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one (ID-690), with special reference to the effects on motor systems].
Topics: Animals; Anticonvulsants; Benzodiazepinones; Clonazepam; Cornea; Diazepam; Dose-Response Relationship, Drug; Drug Synergism; Ear; Male; Mice; Motor Activity; Muscle Relaxants, Central; Nitrazepam; Rats; Reflex; Sciatic Nerve; Sleep; Spinal Cord; Thiopental | 1977 |
[Antiepileptic activity of clonazepam, a benzodiazepine antiepileptic (2). Antiepileptic effects of intravenous injection of clonazepam manifested in EEG].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Benzodiazepinones; Child; Clonazepam; Diazepam; Electroencephalography; Epilepsy; Female; Humans; Injections, Intravenous; Male | 1977 |
[Behavioral effects of 5-(o-chlorophenyl)-1-methyl-7-nitro-1,3-dihydro-2H-1,4-benzodiazepin-2-one (ID-690)].
Topics: Agonistic Behavior; Animals; Anticonvulsants; Behavior, Animal; Benzodiazepinones; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Electroshock; Emotions; Locomotion; Male; Mice; Motor Activity; Nitrazepam; Olfactory Bulb; Rats; Septal Nuclei; Social Isolation | 1977 |
Stiff-man syndrome and clonazepam.
Topics: Benzodiazepinones; Clonazepam; Diazepam; Female; Humans; Middle Aged; Muscle Rigidity; Spasm; Syndrome | 1977 |
Studies on the potency of various antitussive agents.
Topics: Animals; Antitussive Agents; Cats; Clonazepam; Codeine; Cough; Cyclopentanes; Dextromethorphan; Diazepam; Ethylamines; Injections, Intravenous | 1977 |
The temporal dimensions of anticonvulsant action of some newer benzodiazepines against metrazol induced seizures in mice and rats.
Topics: Animals; Benzodiazepines; Clonazepam; Diazepam; Drug Evaluation, Preclinical; Ethosuximide; Female; Flurazepam; Male; Mice; Nitrazepam; Pentylenetetrazole; Phenobarbital; Seizures; Trimethadione | 1977 |
Functional changes in cerebral 5-hydroxytryptamine metabolism in the mouse induced by anticonvulsant drugs.
Topics: Animals; Behavior, Animal; Benzodiazepinones; Brain; Clonazepam; Cytochrome P-450 Enzyme System; Diazepam; Hydroxyindoleacetic Acid; Liver; Male; Mice; Phenytoin; Serotonin; Sleep; Time Factors; Tryptophan | 1978 |
[Stiff--man syndrome].
Topics: Clonazepam; Diagnosis, Differential; Diazepam; Female; Humans; Middle Aged; Muscle Rigidity; Syndrome | 1978 |
Ontogenetic development of benzodiazepine receptors in the rat brain.
Topics: Animals; Animals, Newborn; Binding, Competitive; Brain; Clonazepam; Diazepam; Female; Gestational Age; Male; Pregnancy; Rats; Receptors, Drug | 1978 |
Proposals on antiepileptic pharmacotherapy for use in developing countries.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Developing Countries; Diazepam; Epilepsy; Ethosuximide; Humans; Infant; Phenobarbital; Phenytoin; Valproic Acid | 1976 |
Simplified thin-layer chromatographic method for the stimultaneous determination of clonazepam, diazepam and their metabolites in serum.
Topics: Benzodiazepinones; Chromatography, Thin Layer; Clonazepam; Diazepam; Humans; Methods | 1977 |
[Central effects of clonazepam].
Topics: Animals; Anticonvulsants; Avoidance Learning; Benzodiazepinones; Central Nervous System; Clonazepam; Diazepam; Drug Synergism; Lethal Dose 50; Locomotion; Male; Methamphetamine; Mice; Muscle Contraction; Rats; Thiopental | 1976 |
The effect of diphenylhydantoin, diazepam and clonazepam on the activity of Purkinje cells in the rat cerebellum.
Topics: Action Potentials; Animals; Benzodiazepinones; Clonazepam; Diazepam; Male; Phenytoin; Purkinje Cells; Rats; Time Factors | 1976 |
[Depressive effects of benzodiazepines on penicillin-induced epileptic discharges].
Topics: Animals; Benzodiazepines; Cats; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Electroencephalography; Female; Male; Nitrazepam; Penicillin G; Seizures | 1976 |
The effects of antiepileptic drugs on estrogen-induced electrographic spike-wave discharge.
Topics: Acetazolamide; Animals; Anticonvulsants; Carbamazepine; Cats; Clonazepam; Clorazepate Dipotassium; Diazepam; Electroencephalography; Estrogens; Ethosuximide; Female; Imipramine; Lidocaine; Male; Motor Cortex; Phenytoin; Stereotaxic Techniques; Trimethadione | 1975 |
Letter: The ketogenic diet, West and Lennox syndromes.
Topics: Child; Child, Preschool; Clonazepam; Diazepam; Humans; Infant; Intellectual Disability; Myoclonus; Nitrazepam; Seizures; Spasm; Syndrome | 1975 |
Studies on the localization of central cough mechanism; site of action of antitussive drugs.
Topics: Animals; Antitussive Agents; Benzoates; Binding Sites; Brain Stem; Cats; Clonazepam; Codeine; Cough; Dextromethorphan; Diazepam; Electric Stimulation; Medulla Oblongata | 1975 |
Photically induced epilepsy in Papio papio as a model for drug studies.
Topics: Acetylcholine; Animals; Carbamazepine; Clonazepam; Diazepam; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; gamma-Aminobutyric Acid; Glycine; Humans; Norepinephrine; Papio; Phenobarbital; Phenytoin; Photic Stimulation; Serotonin; Spasms, Infantile | 1975 |
Determination of 1,4-benzodiazepines and -diazepin-2-ones in blood by electron-capture gas-liquid chromatography.
Topics: Benzodiazepines; Benzodiazepinones; Bromazepam; Chromatography, Gas; Clonazepam; Diazepam; Flunitrazepam; Humans | 1976 |
Drugs for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Trimethadione | 1976 |
[Clinical analysis of 30 cases of stiff-man syndrome].
Topics: Adolescent; Adult; Clonazepam; Diazepam; Female; Humans; Male; Middle Aged; Nitrazepam; Reference Standards; Stiff-Person Syndrome | 1992 |
Contractile effect of alpha,beta-methylene ATP on the guinea-pig isolated trachea.
Topics: 2-Chloroadenosine; Adenosine Triphosphate; Animals; Benzodiazepinones; Clonazepam; Diazepam; Drug Synergism; GABA-A Receptor Antagonists; Guinea Pigs; Male; Muscle Contraction; Muscle, Smooth; Phenylisopropyladenosine; Trachea | 1992 |
Effects of central and peripheral type benzodiazepine ligands on thyrotropin and prolactin secretion.
Topics: Animals; Benzodiazepinones; Carbolines; Clonazepam; Cold Temperature; Diazepam; Flumazenil; Hypothalamo-Hypophyseal System; Isoquinolines; Male; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Secretory Rate; Thyrotropin; Thyrotropin-Releasing Hormone | 1992 |
Comparative study of interaction mode of diazepines with human serum albumin and alpha 1-acid glycoprotein.
Topics: Anti-Anxiety Agents; Bromazepam; Clonazepam; Diazepam; Flunitrazepam; Humans; Orosomucoid; Oxazepam; Protein Binding; Regression Analysis; Serum Albumin; Spectrometry, Fluorescence | 1992 |
Tolerance to anticonvulsant effects of clobazam, diazepam, and clonazepam in genetically epilepsy prone rats.
Topics: Acoustic Stimulation; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Clobazam; Clonazepam; Diazepam; Drug Tolerance; Epilepsy; Rats; Rats, Inbred Strains | 1992 |
Comparative effects of carbamazepine, phenytoin, diazepam and clonazepam on inhibitory avoidance learning in mice.
Topics: Animals; Anticonvulsants; Avoidance Learning; Carbamazepine; Clonazepam; Diazepam; Male; Mice; Phenytoin; Reaction Time | 1992 |
Seizures after flumazenil administration in a case of combined benzodiazepine and tricyclic antidepressant overdose.
Topics: Adult; Clonazepam; Diazepam; Drug Overdose; Epilepsy, Tonic-Clonic; Female; Flumazenil; Humans; Imipramine; Poisoning | 1992 |
Repeated administration of diazepam reduces [3H]Ro 5-4864 binding in cerebral cortex of rats.
Topics: Animals; Benzodiazepinones; Cerebral Cortex; Clonazepam; Diazepam; Down-Regulation; Electroencephalography; In Vitro Techniques; Male; Mitochondria; Rats; Rats, Inbred Strains | 1992 |
Interactions between angiotensin II, diazepam, clonazepam and di-n-propylacetate in pentylenetetrazol kindling seizures in mice.
Topics: Angiotensin II; Animals; Clonazepam; Diazepam; Drug Interactions; Electric Stimulation; Ionophores; Kindling, Neurologic; Male; Pentylenetetrazole; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Valproic Acid | 1991 |
SPECT imaging of the benzodiazepine receptor: feasibility of in vivo potency measurements from stepwise displacement curves.
Topics: Alprazolam; Animals; Benzodiazepines; Brain; Brain Chemistry; Clonazepam; Diazepam; Female; Flumazenil; Injections, Intravenous; Macaca mulatta; Male; Papio; Receptors, GABA-A; Tomography, Emission-Computed, Single-Photon | 1991 |
Central and peripheral type benzodiazepine ligands displace [3H][3-ME-HIS2]TRH from its binding sites in the brain and the anterior pituitary and antagonize the effect of TRH in the rat duodenum.
Topics: Animals; Benzodiazepinones; Binding Sites; Brain; Brain Stem; Carbolines; Clonazepam; Diazepam; Duodenum; Hypothalamus; Isoquinolines; Male; Muscle, Smooth; Pituitary Gland, Anterior; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Neurotransmitter; Receptors, Thyrotropin-Releasing Hormone; Thyrotropin-Releasing Hormone | 1991 |
Modulation of GABAB receptors by chronic treatment with clonazepam.
Topics: Animals; Baclofen; Brain; Clonazepam; Diazepam; Male; Muscimol; Radioligand Assay; Rats; Rats, Inbred WKY; Receptors, GABA-A | 1991 |
Central-type benzodiazepines inhibit release of alpha-melanocyte-stimulating hormone from the rat hypothalamus.
Topics: Animals; Anti-Anxiety Agents; beta-Endorphin; Clonazepam; Diazepam; Flumazenil; GABA Antagonists; Hypothalamus; In Vitro Techniques; Male; Melanocyte-Stimulating Hormones; Perfusion; Pituitary Gland; Potassium Chloride; Pro-Opiomelanocortin; Pyridazines; Radioimmunoassay; Rats; Rats, Inbred Strains | 1991 |
Treatment of panic disorder and benzodiazepine withdrawal with valproate.
Topics: Adult; Agoraphobia; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Humans; Male; Panic Disorder; Substance Withdrawal Syndrome; Substance-Related Disorders; Valproic Acid | 1991 |
Characterization of tiagabine (NO-328), a new potent and selective GABA uptake inhibitor.
Topics: Animals; Anticonvulsants; Carbolines; Clonazepam; Convulsants; Diazepam; Female; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred DBA; Neurotransmitter Uptake Inhibitors; Nicotinic Acids; Nipecotic Acids; Pentylenetetrazole; Rats; Rats, Inbred Strains; Seizures; Tiagabine | 1991 |
Relative efficacies of benzodiazepine receptor agonists in affecting red nucleus electrical activity in rabbits.
Topics: Animals; Bicuculline; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Flunitrazepam; Imidazoles; Isoquinolines; Male; Pentylenetetrazole; Pyridazines; Pyridines; Rabbits; Receptors, GABA-A; Red Nucleus; Zolpidem | 1990 |
Prenatal benzodiazepine immunosuppression: possible involvement of peripheral benzodiazepine site.
Topics: Animals; Autoradiography; Benzodiazepinones; Binding Sites; Cell Division; Clonazepam; Convulsants; Diazepam; Female; Immune Tolerance; Immunity, Cellular; Lymphocytes; Male; Maternal-Fetal Exchange; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Receptors, GABA-A | 1990 |
Peripheral type benzodiazepine receptors and response to adenosine on the guinea-pig isolated trachea.
Topics: Adenosine; Animals; Benzodiazepines; Clonazepam; Diazepam; Dipyridamole; Drug Synergism; GABA-A Receptor Antagonists; Guinea Pigs; Histamine; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Receptors, GABA-A; Theophylline; Trachea | 1990 |
Benzodiazepine receptor ligand influences on acquisition: suggestion of an endogenous modulatory mechanism mediated by benzodiazepine receptors.
Topics: Animals; Anti-Anxiety Agents; Arousal; Avoidance Learning; Benzodiazepinones; Brain; Carbolines; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Exploratory Behavior; Female; Flumazenil; Habituation, Psychophysiologic; Memory; Mental Recall; Rats; Rats, Inbred Strains; Reaction Time; Receptors, GABA-A; Retention, Psychology | 1990 |
Relaxant effect of benzodiazepines on uterine rings isolated from estrogen-treated rats.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Bicuculline; Clonazepam; Convulsants; Diazepam; Estradiol; Estrogens; Female; Flumazenil; In Vitro Techniques; Isoquinolines; Muscle, Smooth; Potassium Chloride; Propranolol; Rats; Rats, Inbred Strains; Uterine Contraction | 1990 |
Chronic benzodiazepine treatment and cortical responses to adenosine and GABA.
Topics: Adenosine; Animals; Anti-Anxiety Agents; Cerebral Cortex; Clonazepam; Diazepam; Electrodes; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Mice; N-Methylaspartate; Serotonin; Theophylline | 1990 |
Characterization by saturation studies of the in vivo binding of [3H]flunitrazepam in mouse brain.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Clonazepam; Diazepam; Flunitrazepam; Kinetics; Mice; Nordazepam; Oxazepam | 1991 |
[Veratramine-induced myoclonus].
Topics: Animals; Brain; Clonazepam; Diazepam; Male; Mice; Myoclonus; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Veratrum Alkaloids | 1990 |
Antimyoclonic effect of MK-801: a possible role for NMDA receptors in developmental myoclonus of the neonatal rat.
Topics: Aminobutyrates; Analysis of Variance; Animals; Animals, Newborn; Anticonvulsants; Clonazepam; Diazepam; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Isoxazoles; Kynurenic Acid; Male; Myoclonus; N-Methylaspartate; Quisqualic Acid; Rats; Receptors, N-Methyl-D-Aspartate; Strychnine | 1990 |
Involvement of the "peripheral" benzodiazepine receptor type (omega 3) in the tolerance to the electroencephalographic effects of benzodiazepines in rats: comparison of diazepam and clonazepam.
Topics: Animals; Benzodiazepinones; Clonazepam; Diazepam; Drug Tolerance; Electroencephalography; Isoquinolines; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1990 |
Profound stress-induced alterations in flurazepam's antiseizure efficacy can be attenuated.
Topics: Animals; Carbolines; Clonazepam; Cold Temperature; Diazepam; Dose-Response Relationship, Drug; Electroshock; Flumazenil; Flurazepam; Male; Mice; Mice, Inbred Strains; Midazolam; Seizures; Stress, Psychological | 1990 |
EEG monitoring of therapy for neonatal seizures.
Topics: Anticonvulsants; Chloral Hydrate; Clonazepam; Diazepam; Drug Therapy, Combination; Electroencephalography; Evoked Potentials; Humans; Infant, Newborn; Infant, Premature, Diseases; Phenobarbital; Recurrence; Signal Processing, Computer-Assisted; Spasms, Infantile | 1990 |
The diagnosis and treatment of panic disorder in alcoholics: three cases.
Topics: Adult; Alcohol Drinking; Alcoholism; Anxiety Disorders; Clonazepam; Diazepam; Follow-Up Studies; Humans; Lactates; Lactic Acid; Lorazepam; Male; Middle Aged; Panic; Perphenazine | 1990 |
[Therapeutic drug monitoring of clonazepam, nitrazepam and diazepam].
Topics: Age Factors; Biological Availability; Chromatography, Gas; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Clonazepam; Diazepam; Dosage Forms; Epilepsy; Humans; Nitrazepam; Sex Factors; Specimen Handling | 1990 |
Partial agonists of the benzodiazepine receptor: from animal data to results in patients.
Topics: Affinity Labels; Allosteric Site; Animals; Azides; Benzodiazepines; Benzodiazepinones; Chlordiazepoxide; Chlorides; Clonazepam; Diazepam; Drug Interactions; Ethanol; Flumazenil; Flurazepam; Humans; Ion Channels; Ligands; Models, Neurological; Neurons; Receptors, GABA-A | 1988 |
"Central" and "peripheral" benzodiazepines and kinetics of lindane-induced toxicity.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Body Temperature; Clonazepam; Diazepam; Drug Interactions; Female; Hexachlorocyclohexane; Male; Phenytoin; Rats; Rats, Inbred Strains | 1989 |
Diminution by benzodiazepines of the chronotropic responses to noradrenaline in rat isolated atria.
Topics: 1-Methyl-3-isobutylxanthine; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anti-Anxiety Agents; Benzodiazepinones; Clonazepam; Colforsin; Cyclic AMP; Diazepam; Female; Flumazenil; Heart; Heart Rate; In Vitro Techniques; Isoquinolines; Male; Myocardium; Norepinephrine; Rats; Rats, Inbred Strains | 1989 |
Radioreceptor assay of clonazepam and diazepam in blood for therapeutic drug monitoring.
Topics: Adolescent; Animals; Child; Child, Preschool; Chromatography, Gas; Chromatography, High Pressure Liquid; Clonazepam; Diazepam; Flunitrazepam; Humans; Male; Nordazepam; Radioligand Assay; Rats | 1989 |
Prenatal diazepam induced persisting depression of cellular immune responses.
Topics: Animals; Clonazepam; Corticosterone; Diazepam; Female; Fetus; Immunity, Cellular; Lymphocyte Activation; Male; Pregnancy; Rats; Receptors, GABA-A; T-Lymphocytes | 1989 |
Effects of peripheral benzodiazepines upon the O2 consumption of neuroblastoma cells.
Topics: Animals; Benzodiazepines; Cells, Cultured; Clonazepam; Clone Cells; Diazepam; Flumazenil; Isoquinolines; Mice; Mitochondria; Neuroblastoma; Oxygen Consumption; Receptors, GABA-A | 1989 |
Antiproliferative action of benzodiazepines in cultured brain cells is not mediated through the peripheral-type benzodiazepine acceptor.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Blood; Cell Division; Clonazepam; Diazepam; DNA; Glioma; Isoquinolines; Mice; Neuroblastoma; Rats; Receptors, GABA-A; Tumor Cells, Cultured | 1989 |
Early developmental exposure to benzodiazepine ligands alters brain levels of thiobarbituric acid-reactive products in young adult rats.
Topics: Animals; Benzodiazepines; Brain; Clonazepam; Diazepam; Female; Flumazenil; Gestational Age; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Receptors, GABA-A; Thiobarbiturates | 1989 |
Adjunctive buspirone in benzodiazepine treatment of four patients with panic disorder.
Topics: Adult; Alprazolam; Anti-Anxiety Agents; Anxiety; Buspirone; Clonazepam; Diazepam; Drug Combinations; Fear; Female; Humans; Male; Middle Aged; Panic; Phobic Disorders | 1989 |
Benzodiazepines decrease the release of [3H]noradrenaline and of [3H]acetylcholine in the cat superior cervical ganglion.
Topics: Acetylcholine; Animals; Anti-Anxiety Agents; Cats; Clonazepam; Diazepam; Electric Stimulation; Ganglia, Sympathetic; Neurons; Nictitating Membrane; Norepinephrine | 1989 |
Sexual dysfunction associated with diazepam but not with clonazepam.
Topics: Adult; Anxiety Disorders; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Erectile Dysfunction; Fear; Humans; Male; Middle Aged; Panic | 1989 |
Testing drug effects against hypoxic damage of cultured neurons during long-term recovery.
Topics: Adenosine Triphosphate; Animals; Anticonvulsants; Brain Ischemia; Cell Count; Cell Survival; Cells, Cultured; Chick Embryo; Clonazepam; Diazepam; Dibenzocycloheptenes; Dizocilpine Maleate; Flunarizine; Haloperidol; Imipramine; Ketamine; Lidocaine; Nafronyl; Neurons; Pyrithioxin; Telencephalon | 1989 |
Testicular interstitial cells as targets for peripheral benzodiazepines.
Topics: Animals; Benzodiazepinones; Clonazepam; Diazepam; In Vitro Techniques; Isoquinolines; Leydig Cells; Male; Rats; Rats, Inbred Strains; Testosterone | 1989 |
Synergistic anticonvulsant action of diazepam & clonazepam with amino-oxyacetic acid against isoniazid-induced convulsions in rats.
Topics: Acetates; Aminooxyacetic Acid; Animals; Clonazepam; Diazepam; Drug Therapy, Combination; Isoniazid; Male; Rats; Rats, Inbred Strains; Seizures | 1989 |
Lack of promoting effect of clonazepam on the development of N-nitrosodiethylamine-initiated hepatocellular tumors in mice is correlated with its inability to inhibit cell-to-cell communication in mouse hepatocytes.
Topics: Adenoma; Aminopyrine N-Demethylase; Animals; Carcinogens; Carcinoma; Cell Communication; Clonazepam; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Diazepam; Diethylnitrosamine; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred Strains; Oxidoreductases; Phenobarbital | 1989 |
Agenesis of the corpus callosum and gyral malformations are frequent manifestations of nonketotic hyperglycinemia.
Topics: Agenesis of Corpus Callosum; Amino Acid Metabolism, Inborn Errors; Brain; Cerebral Ventriculography; Clonazepam; Corpus Callosum; Diazepam; Electroencephalography; Glycine; Humans; Infant, Newborn; Male; Tomography, X-Ray Computed | 1989 |
[Effects of anticonvulsants on the cyclic nucleotide content of the plasma and cerebellum of convulsive rats].
Topics: Animals; Anticonvulsants; Cerebellum; Clonazepam; Cyclic AMP; Cyclic GMP; Diazepam; Male; Organophosphorus Compounds; Rats; Scopolamine; Seizures; Soman | 1987 |
Benzodiazepine receptor development in murine glial cultures.
Topics: Animals; Animals, Newborn; Benzodiazepinones; Binding, Competitive; Cells, Cultured; Clonazepam; Diazepam; Mice; Neuroglia; Receptors, GABA-A | 1987 |
Benzodiazepines and barbiturate potentiate the pre- and postsynaptic gamma-aminobutyric acid (GABA)A receptor-mediated response in the enteric nervous system of guinea pig small intestine.
Topics: Acetylcholine; Animals; Barbiturates; Benzodiazepines; Clonazepam; Diazepam; Female; Flumazenil; Guinea Pigs; Intestine, Small; Male; Muscimol; Pentobarbital; Potassium; Receptors, GABA-A | 1988 |
[Validation of a method for detecting benzodiazepines in the urine by acid extraction of their benzophenones and thin layer chromatography].
Topics: Anti-Anxiety Agents; Benzodiazepines; Benzophenones; Bromazepam; Chromatography, Gas; Chromatography, Thin Layer; Clonazepam; Diazepam; Humans; Hydrogen-Ion Concentration; Hydrolysis; Lorazepam; Nitrazepam | 1985 |
[Some suggestions on epileptic psychoses, their differential diagnosis and therapy].
Topics: Anticonvulsants; Antipsychotic Agents; Clonazepam; Dementia; Diagnosis, Differential; Diazepam; Drug Therapy, Combination; Electroencephalography; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Humans; Neurocognitive Disorders | 1986 |
Oral benzodiazepines as prophylaxis for epilepsy.
Topics: Administration, Oral; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Clobazam; Clonazepam; Diazepam; Epilepsy; Humans; Nitrazepam | 1986 |
Benzodiazepine, beta-carboline, and barbiturate actions on GABA responses.
Topics: Animals; Anti-Anxiety Agents; Barbiturates; Bicuculline; Carbolines; Cells, Cultured; Clonazepam; Diazepam; gamma-Aminobutyric Acid; Membrane Potentials; Mice; Neurons; Nitrazepam; Pentobarbital; Phenobarbital; Picrotoxin; Receptors, GABA-A; Spinal Cord | 1986 |
Neurotransmitter changes during development of cortical neuronal cultures.
Topics: Animals; Benzodiazepinones; Cells, Cultured; Cerebral Cortex; Choline O-Acetyltransferase; Clonazepam; Diazepam; Fetus; Flunitrazepam; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Mice; Neurotransmitter Agents | 1986 |
Modulation of GABA-stimulated chloride influx into membrane vesicles from rat cerebral cortex by benzodiazepines and nonbenzodiazepines.
Topics: Animals; Anti-Anxiety Agents; Cell Membrane; Cerebral Cortex; Chlorides; Clonazepam; Diazepam; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Rats; Rats, Inbred Strains | 1988 |
7-[125I]iodoclonazepam: purification by high-performance liquid chromatography for use in a very sensitive benzodiazepine radioimmunoassay of broad specificity.
Topics: Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Chromatography, High Pressure Liquid; Clonazepam; Diazepam; Humans; Iodine Radioisotopes; Radioimmunoassay | 1988 |
The effects of benzodiazepines on spinal homosynaptic depression.
Topics: Animals; Benzodiazepinones; Cats; Clonazepam; Diazepam; Female; Flumazenil; Male; Receptors, GABA-A; Reflex, Monosynaptic; Reflex, Stretch; Spinal Nerve Roots; Synapses | 1985 |
Benzodiazepine binding characteristics of embryonic rat brain neurons grown in culture.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Brain; Carbolines; Cells, Cultured; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Flumazenil; gamma-Aminobutyric Acid; Neurons; Pyridazines; Rats; Receptors, GABA-A | 1985 |
Solubilization of peripheral benzodiazepine-binding sites from rat kidney.
Topics: Animals; Benzodiazepinones; Binding, Competitive; Carbolines; Chlordiazepoxide; Clonazepam; Diazepam; Digitonin; Flumazenil; Flurazepam; Guanidine; Guanidines; Hot Temperature; Isoquinolines; Kidney; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Solubility; Time Factors; Urea | 1985 |
Pharmacology of peripheral type benzodiazepine receptors in the heart.
Topics: Action Potentials; Animals; Benzodiazepinones; Clonazepam; Convulsants; Diazepam; Electric Stimulation; Guinea Pigs; Heart; Heart Ventricles; Isoquinolines; Kinetics; Myocardial Contraction; Myocardium; Receptors, GABA-A; Ventricular Function | 1985 |
Convulsant effect of Ro 5-4864, a peripheral type benzodiazepine, on the baboon (Papio papio).
Topics: Animals; Benzodiazepines; Benzodiazepinones; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Isoquinolines; Papio; Receptors, GABA-A; Seizures | 1986 |
Comparison of benzodiazepine receptors in cerebellum and inferior colliculus.
Topics: Aging; Animals; Animals, Newborn; Carbolines; Cell Membrane; Cerebellum; Clonazepam; Diazepam; Flunitrazepam; Inferior Colliculi; Pyridazines; Rats; Receptors, GABA-A | 1986 |
Peripheral benzodiazepines enhance the respiratory burst of macrophage-like P388D1 cells stimulated by arachidonic acid.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Benzodiazepinones; Cell Line; Clonazepam; Diazepam; Isoquinolines; Kinetics; Macrophages; Receptors, GABA-A; Superoxides | 1987 |
[Grand mal seizures and status epilepticus in general practice-- what's to be done?].
Topics: Adult; Aged; Child, Preschool; Clonazepam; Diazepam; Emergencies; Epilepsy, Tonic-Clonic; Family Practice; Humans; Infant; Injections, Intramuscular; Injections, Intravenous; Middle Aged; Phenobarbital; Status Epilepticus; Suppositories | 1986 |
[Clinical treatment of grand mal epileptic status in adults].
Topics: Adult; Barbiturates; Chlormethiazole; Clonazepam; Diazepam; Emergencies; Epilepsy, Tonic-Clonic; Humans; Oxygen Inhalation Therapy; Phenytoin; Status Epilepticus | 1986 |
Benzodiazepine cross-tolerance in mice extends to sodium valproate.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Clobazam; Clonazepam; Diazepam; Drug Tolerance; Lorazepam; Male; Mice; Pentylenetetrazole; Phenobarbital; Valproic Acid | 1986 |
Diazepam-sensitive specific binding of phenytoin in rat brain.
Topics: Animals; Benzodiazepinones; Binding Sites; Cell Membrane; Cerebral Cortex; Clonazepam; Diazepam; Flumazenil; Male; Phenytoin; Rats; Rats, Inbred Strains | 1986 |
Inhibition of cell proliferation of human gliomas by benzodiazepines in vitro.
Topics: Astrocytoma; Benzodiazepines; Benzodiazepinones; Cell Division; Clonazepam; Diazepam; Female; Flumazenil; Glioma; Humans; Male; Middle Aged; Thymidine; Tumor Cells, Cultured | 1988 |
Benzodiazepine enhancement of gamma-aminobutyric acid-mediated chloride ion flux in rat brain synaptoneurosomes.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Brain; Carbolines; Chlorides; Clonazepam; Diazepam; Drug Synergism; Flurazepam; gamma-Aminobutyric Acid; Male; Muscimol; Rats; Rats, Inbred Strains; Synaptosomes | 1988 |
Central administration of benzodiazepines alters water absorption by the rat ileum in vivo.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Clonazepam; Diazepam; Ileum; Injections, Intraventricular; Intestinal Absorption; Lorazepam; Male; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Water | 1987 |
Cholinergic induction of seizures in the rat prefrontal cortex.
Topics: Animals; Carbachol; Cerebral Cortex; Clonazepam; Diazepam; Electroencephalography; Male; Microinjections; Pentobarbital; Phenytoin; Rats; Rats, Inbred Strains; Seizures; Stereotyped Behavior | 1986 |
Benzodiazepines in the treatment of children with epilepsy.
Topics: Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Child; Child, Preschool; Clobazam; Clonazepam; Diazepam; Drug Tolerance; Epilepsy; Humans; Infant; Lorazepam; Nitrazepam | 1986 |
The antimitotic activities of some benzodiazepines.
Topics: Benzodiazepines; Chlorophyta; Chromosomes; Clonazepam; Diazepam; Flunitrazepam; Medazepam; Mitosis; Nitrazepam | 1986 |
Multisystem degeneration: drugs and square wave jerks.
Topics: Clonazepam; Diazepam; Female; gamma-Aminobutyric Acid; Humans; Middle Aged; Nystagmus, Pathologic; Phenobarbital; Thiamylal | 1986 |
Voice tremor: dysregulation of voluntary expiratory muscles.
Topics: Clonazepam; Diazepam; Double-Blind Method; Electromyography; Humans; Propranolol; Respiratory Muscles; Trihexyphenidyl; Voice Disorders | 1987 |
Effects of single and repeated application of clonazepam and diazepam combined with cyproheptadine on apomorphine stereotypy in rats.
Topics: Animals; Apomorphine; Benzodiazepinones; Clonazepam; Cyproheptadine; Diazepam; Dopamine; Humans; Male; Rats; Rats, Inbred Strains; Stereotyped Behavior | 1985 |
[Convulsive crises in childhood].
Topics: Clonazepam; Crying; Diagnosis, Differential; Diazepam; Epilepsy; Humans; Infant; Infant, Newborn; Migraine Disorders; Phenobarbital; Phenytoin; Respiratory Insufficiency; Seizures; Seizures, Febrile; Syncope; Vertigo | 1985 |
Electrophysiological and pharmacological characterization of peripheral benzodiazepine receptors in a guinea pig heart preparation.
Topics: Action Potentials; Animals; Benzodiazepinones; Clonazepam; Convulsants; Diazepam; Dose-Response Relationship, Drug; Electric Stimulation; Flumazenil; Guinea Pigs; Heart; In Vitro Techniques; Isoquinolines; Myocardial Contraction; Myocardium; Receptors, Cell Surface; Receptors, GABA-A | 1984 |
Flunitrazepam binding to intact and homogenized astrocytes and neurons in primary cultures.
Topics: Animals; Astrocytes; Benzodiazepinones; Cells, Cultured; Clonazepam; Diazepam; Flunitrazepam; Kinetics; Mice; Neurons; Receptors, GABA-A; Temperature | 1984 |
Autoradiographic localization of benzodiazepine receptors in the rat kidney.
Topics: Animals; Autoradiography; Benzodiazepinones; Clonazepam; Diazepam; Flunitrazepam; Kidney; Kidney Tubules, Distal; Loop of Henle; Male; Mucoproteins; Rats; Rats, Inbred Strains; Receptors, GABA-A; Tritium; Uromodulin | 1984 |
Benzodiazepine binding sites in human myometrium.
Topics: Adult; Benzodiazepinones; Binding Sites; Cell Membrane; Clonazepam; Diazepam; Female; Flunitrazepam; Humans; In Vitro Techniques; Lorazepam; Middle Aged; Myometrium; Receptors, GABA-A | 1984 |
Analysis of benzodiazepine binding sites in rat pituitary gland.
Topics: Animals; Benzodiazepinones; Binding, Competitive; Clonazepam; Diazepam; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Pituitary Gland; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1984 |
Benzodiazepine binding sites in human pineal gland.
Topics: Adolescent; Adult; Aged; Animals; Benzodiazepinones; Binding, Competitive; Cerebral Cortex; Child; Child, Preschool; Clonazepam; Diazepam; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Infant; Kinetics; Male; Middle Aged; Pineal Gland; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1984 |
Effect of estazolam on the caudate spindle in the cat.
Topics: Animals; Anti-Anxiety Agents; Cats; Caudate Nucleus; Clonazepam; Diazepam; Electroencephalography; Estazolam; Female; Flunitrazepam; Male | 1981 |
Effect of benzodiazepine derivatives on amygdaloid-kindled convulsion.
Topics: Amygdala; Animals; Anti-Anxiety Agents; Anticonvulsants; Bromazepam; Clonazepam; Diazepam; Kindling, Neurologic; Lorazepam; Male; Nitrazepam; Rats; Rats, Inbred Strains | 1982 |
Effects of some benzodiazepines on the acetylcholine release in the anterior horn of the lateral cerebral ventricle of the cat.
Topics: Acetylcholine; Animals; Anti-Anxiety Agents; Benzodiazepinones; Cats; Cerebral Ventricles; Clonazepam; Diazepam; Flunitrazepam; Male | 1982 |
Benzodiazepines modulate the A2 adenosine binding sites on 108CC15 neuroblastoma X glioma hybrid cells.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Binding, Competitive; Cells, Cultured; Clonazepam; Cyclic AMP; Diazepam; Glioma; Hybrid Cells; Kinetics; Neuroblastoma; Phosphodiesterase Inhibitors; Pyrrolidinones; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Purinergic; Rolipram | 1984 |
Fetal toxicity of benzodiazepines in rats.
Topics: Abnormalities, Drug-Induced; Animals; Anti-Anxiety Agents; Chlordiazepoxide; Clonazepam; Diazepam; Female; Fetal Resorption; Fetus; Male; Nitrazepam; Oxazepam; Pregnancy; Rats; Rats, Inbred Strains | 1984 |
Benzodiazepines and GABAergic regulation of nigrostriatal neurons: lack of tolerance.
Topics: Animals; Anti-Anxiety Agents; Clonazepam; Corpus Striatum; Diazepam; Male; Nitrazepam; Rats; Rats, Inbred Strains; Substantia Nigra | 1984 |
Properties of [3H]diazepam binding sites on rat blood platelets.
Topics: Animals; Benzodiazepinones; Blood Platelets; Clonazepam; Diazepam; Hydrogen-Ion Concentration; Kinetics; Male; Rats; Receptors, Drug; Receptors, GABA-A; Temperature | 1980 |
beta-Carboline inhibition of benzodiazepine receptor binding in vivo.
Topics: Animals; Binding, Competitive; Carbolines; Clonazepam; Diazepam; Flunitrazepam; Indoles; Male; Muridae; Receptors, Drug; Receptors, GABA-A | 1982 |
Peripheral benzodiazepine binding sites: effect of PK 11195, 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide. I. In vitro studies.
Topics: Adrenal Glands; Animals; Benzodiazepinones; Blood Platelets; Brain; Clonazepam; Diazepam; In Vitro Techniques; Isoquinolines; Kidney; Male; Myocardium; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Tissue Distribution | 1983 |
Peripheral benzodiazepine binding sites: effect of PK 11195, 1-(2-chlorophenyl)-N-methyl-(1-methylpropyl)-3 isoquinolinecarboxamide. II. In vivo studies.
Topics: Animals; Benzodiazepinones; Brain; Clonazepam; Diazepam; Isoquinolines; Kidney; Kinetics; Male; Mice; Myocardium; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Acute effects of drug administration and withdrawal on the benzodiazepine receptor.
Topics: Animals; Benzodiazepines; Cerebral Cortex; Clonazepam; Diazepam; Flurazepam; Humans; Lorazepam; Male; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Substance Withdrawal Syndrome | 1983 |
Properties of two benzodiazepine binding sites in spinal cord.
Topics: Animals; Benzodiazepines; Binding Sites; Brain; Clonazepam; Diazepam; Glycine; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Spinal Cord; Strychnine | 1983 |
Development and differentiation of the benzodiazepine receptor in cultures of fetal mouse spinal cord.
Topics: Animals; Benzodiazepinones; Cell Differentiation; Clonazepam; Diazepam; Fetus; Flunitrazepam; Kinetics; Mice; Neurons; Receptors, Cell Surface; Receptors, GABA-A; Spinal Cord | 1983 |
Differentiation between two ligands for peripheral benzodiazepine binding sites, [3H]RO5-4864 and [3H]PK 11195, by thermodynamic studies.
Topics: Animals; Benzodiazepinones; Clonazepam; Diazepam; Dipyridamole; Isoquinolines; Ligands; Male; Membranes; Myocardium; Rats; Receptors, Cell Surface; Receptors, GABA-A; Thermodynamics | 1983 |
Pyrethroids of the most potent class antagonize GABA action at the crayfish neuromuscular junction.
Topics: Animals; Astacoidea; Clonazepam; Diazepam; GABA Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Neuromuscular Junction; Picrotoxin; Pyrethrins; Receptors, Cell Surface; Receptors, GABA-A; Sesterterpenes; Synaptic Transmission | 1983 |
Micromolar-affinity benzodiazepine receptors regulate voltage-sensitive calcium channels in nerve terminal preparations.
Topics: Animals; Benzodiazepines; Brain; Calcium; Cations, Divalent; Clonazepam; Diazepam; Female; Flunitrazepam; Ion Channels; Kinetics; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Synaptosomes | 1984 |
Inhibition of cold-induced TSH release by benzodiazepines.
Topics: Animals; Benzodiazepinones; Clonazepam; Cold Temperature; Depression, Chemical; Diazepam; Drug Interactions; Flumazenil; Male; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Thyrotropin; Thyrotropin-Releasing Hormone | 1983 |
Selective effects of diltiazem, a benzothiazepine calcium channel blocker, and diazepam, and other benzodiazepines on the Na+/Ca2+ exchange carrier system of heart and brain mitochondria.
Topics: Animals; Benzazepines; Benzodiazepines; Benzodiazepinones; Brain; Calcium; Carrier Proteins; Clonazepam; Diazepam; Diltiazem; Flumazenil; Mitochondria; Mitochondria, Heart; Rabbits; Rats; Sodium; Sodium-Calcium Exchanger | 1983 |
Effects of some anticonvulsant drugs on brain GABA level and GAD and GABA-T activities.
Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Brain; Carbamazepine; Clonazepam; Diazepam; gamma-Aminobutyric Acid; Male; Mice; Oxidoreductases; Phenobarbital; Phenytoin; Valproic Acid | 1984 |
Specific binding of [3H]diazepam in mouse glioblastoma: the influence of clonazepam and Ro 5-4864 on [3H]diazepam binding.
Topics: Animals; Benzodiazepinones; Binding Sites; Cell Line; Clonazepam; Diazepam; Glioma; Mice; Neuroglia | 1984 |
Familial reflex myoclonus in Labrador Retrievers.
Topics: Animals; Clonazepam; Diazepam; Dog Diseases; Dogs; Electromyography; Evoked Potentials; Male; Muscles; Myoclonus; Pedigree | 1984 |
Effects of single and repeated application of clonazepam and diazepam independently and in combination with cyproheptadine on apomorphine stereotypy in rats.
Topics: Animals; Apomorphine; Benzodiazepinones; Clonazepam; Cyproheptadine; Diazepam; Humans; Male; Rats; Rats, Inbred Strains; Receptors, Serotonin; Stereotyped Behavior | 1984 |
[3H]diazepam binding sites on chick neurons in primary culture.
Topics: Animals; Benzodiazepinones; Binding Sites; Binding, Competitive; Cells, Cultured; Chick Embryo; Clonazepam; Diazepam; gamma-Aminobutyric Acid; Neurons; Pentobarbital; Telencephalon | 1983 |
[Effect of benzodiazepines on neuropathologic syndromes of spinal origin].
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Clonazepam; Diazepam; Myoclonus; Pain; Rats; Spinal Cord Diseases | 1984 |
Properties of [3H]diazepam binding sites on cultured murine glia and neurons.
Topics: Animals; Animals, Newborn; Benzodiazepinones; Binding Sites; Cells, Cultured; Cerebral Cortex; Clonazepam; Diazepam; Kinetics; Mice; Neuroglia; Neurons | 1984 |
Comparison of the effects of naloxone and picrotoxin on schedule-controlled responding in the pigeon: possible GABA-antagonistic effects of naloxone.
Topics: Animals; Clonazepam; Columbidae; Conditioning, Operant; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; GABA Antagonists; Male; Naloxone; Pentobarbital; Picrotoxin | 1984 |
[Termination of status epilepticus with sodium valproate].
Topics: Clonazepam; Diazepam; Humans; Infant; Phenytoin; Status Epilepticus; Valproic Acid | 1980 |
Anticonvulsant-induced status epilepticus in Lennox-Gastaut syndrome.
Topics: Adolescent; Adult; Benzodiazepinones; Carbamazepine; Child; Child, Preschool; Chlormethiazole; Clonazepam; Diazepam; Drug Combinations; Electroencephalography; Epilepsy, Absence; Female; Humans; Phenytoin; Primidone; Status Epilepticus | 1981 |
Radioimmunoassay of benzodiazepines.
Topics: Benzodiazepines; Chlordiazepoxide; Clonazepam; Diazepam; Flurazepam; Humans; Microchemistry; Nitrazepam; Nordazepam; Oxazepam; Radioimmunoassay | 1982 |
Benzodiazepines: efficacy in status epilepticus.
Topics: Adult; Aged; Benzodiazepines; Child; Clonazepam; Diazepam; Electroencephalography; Humans; Status Epilepticus | 1983 |
Experimental chronic epilepsy in rats: a screening method for antiepileptic drugs.
Topics: Animals; Anticonvulsants; Chlorides; Chronic Disease; Clonazepam; Diazepam; Disease Models, Animal; Drug Evaluation, Preclinical; Electroencephalography; Ferric Compounds; Male; Rats; Rats, Inbred Strains; Seizures | 1983 |
Segmental action and stimuli-sensitive myoclonus with acute onset. A case report.
Topics: 5-Hydroxytryptophan; Acute Disease; Adult; Angiography; Carbidopa; Carotid Arteries; Cerebrovascular Circulation; Clonazepam; Diazepam; Electric Stimulation; Electroencephalography; Humans; Male; Myoclonus; Vertebral Artery | 1980 |
Heterogeneity of cerebral capillary flow in man and its consequences for estimation of blood-brain barrier permeability.
Topics: Blood Glucose; Blood-Brain Barrier; Capillaries; Cerebrovascular Circulation; Clonazepam; Diazepam; Erythrocytes; Humans; Indicator Dilution Techniques; Nitrazepam; Permeability; Phenylalanine; Propranolol; Water | 1980 |
Blood-brain barrier transfer and cerebral uptake of antiepileptic drugs.
Topics: Anticonvulsants; Blood-Brain Barrier; Brain; Clonazepam; Diazepam; Humans; Models, Biological; Phenobarbital; Phenytoin; Time Factors | 1982 |
Arterial and venous concentrations of phenobarbital, phenytoin, clonazepam, and diazepam after rapid intravenous injections.
Topics: Anticonvulsants; Arteries; Clonazepam; Diazepam; Humans; Injections, Intravenous; Phenobarbital; Phenytoin; Time Factors; Veins | 1982 |
Attenuation of normeperidine's suppressing effect on schedule-controlled behavior.
Topics: Animals; Clonazepam; Columbidae; Conditioning, Psychological; Diazepam; Male; Meperidine; Pentobarbital | 1982 |
Benzodiazepines prevent kainate-induced loss of GABAergic and cholinergic neurons in the chick retina.
Topics: Animals; Benzodiazepinones; Biological Transport; Chickens; Clonazepam; Diazepam; gamma-Aminobutyric Acid; Kainic Acid; Neurons; Pyrrolidines; Retina | 1981 |
[Pharmacological influences on the brain level and transport of GABA. I) Effect of various antipileptic drugs on brain levels of GABA].
Topics: Animals; Biological Transport; Brain; Carbamazepine; Clonazepam; Diazepam; gamma-Aminobutyric Acid; Mice; Phenobarbital; Phenytoin | 1981 |
Psychomotor status induced by temporal lobe encephalitis.
Topics: Automatism; Carbamazepine; Clonazepam; Diazepam; Electroencephalography; Encephalitis; Epilepsy, Temporal Lobe; Humans; Male; Middle Aged; Temporal Lobe | 1981 |
Intravenous clonazepam in the treatment of status epilepticus in children.
Topics: Adolescent; Benzodiazepinones; Child; Child, Preschool; Clonazepam; Diazepam; Electroencephalography; Evoked Potentials; Humans; Infant; Infant, Newborn; Infusions, Parenteral; Recurrence; Status Epilepticus | 1980 |
Characterization of benzodiazepine receptors in primary cultures of fetal mouse brain and spinal cord neurons.
Topics: Animals; Binding, Competitive; Brain; Clonazepam; Culture Techniques; Diazepam; Female; gamma-Aminobutyric Acid; Inosine; Mice; Mice, Inbred C57BL; Neurons; Pregnancy; Receptors, Drug; Spinal Cord | 1980 |
Diazepam receptors on mouse astrocytes in primary cultures: displacement by pharmacologically active concentrations of benzodiazepines or barbiturates.
Topics: Animals; Astrocytes; Barbiturates; Benzodiazepines; Binding Sites; Binding, Competitive; Cells, Cultured; Clonazepam; Diazepam; Flurazepam; Mice; Pentobarbital; Phenobarbital; Receptors, Drug | 1980 |
Benzodiazepines influence melatonin secretion of the pineal organ of the trout in vitro.
Topics: 5-Methoxytryptamine; Animals; Benzodiazepines; Calcium; Clonazepam; Culture Media; Dark Adaptation; Diazepam; Flumazenil; Hydroxyindoleacetic Acid; In Vitro Techniques; Indoles; Isoquinolines; Light; Magnesium; Melatonin; Oncorhynchus mykiss; Pineal Gland | 1994 |
Drug discrimination analysis of midazolam under a three-lever procedure. II: Differential effects of benzodiazepine receptor agonists.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Clonazepam; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Drug Interactions; GABA Modulators; GABA-A Receptor Agonists; Hypnotics and Sedatives; Male; Midazolam; Pyridines; Rats; Rats, Sprague-Dawley; Zolpidem | 1995 |
Vascular and tubular actions of diazepam in isolated and perfused rat kidney.
Topics: Animals; Benzodiazepinones; Biological Transport, Active; Blood Vessels; Clonazepam; Convulsants; Diazepam; Diuresis; In Vitro Techniques; Kidney Function Tests; Kidney Tubules; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Natriuresis; Norepinephrine; Potassium Chloride; Rats; Rats, Wistar; Renal Circulation | 1995 |
Benzodiazepine agonists reverse the effects of noise exposure on central benzodiazepine receptors and cardiac responsiveness.
Topics: Animals; Brain; Clonazepam; Diazepam; Flumazenil; Imidazoles; Male; Myocardium; Noise; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, GABA-A; Stress, Psychological | 1995 |
Identification of parent benzodiazepines by gas chromotography/mass spectroscopy (GC/MS) from urinary extracts treated with B-glucuronidase.
Topics: Alprazolam; Benzodiazepines; Chlordiazepoxide; Clonazepam; Diazepam; Gas Chromatography-Mass Spectrometry; Glucuronidase; Humans; Lorazepam; Oxazepam; Triazolam | 1995 |
[Diazepam-induced EEG changes as a predictor of the outcome of epilepsy].
Topics: Clonazepam; Diazepam; Electroencephalography; Epilepsy; Female; Follow-Up Studies; Humans; Male; Prognosis | 1993 |
Determination of oxazepam and diazepam in body fluids by HPLC.
Topics: Chromatography, High Pressure Liquid; Clonazepam; Diazepam; Humans; Oxazepam; Regression Analysis; Reproducibility of Results; Sensitivity and Specificity | 1993 |
[Drug therapy and its problems in epilepsy].
Topics: Clonazepam; Diazepam; Emergencies; Epilepsy; Humans | 1993 |
The prognostic significance of diazepam-induced EEG changes in epilepsy: a follow-up study.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Beta Rhythm; Child; Clonazepam; Diazepam; Drug Therapy, Combination; Electroencephalography; Epilepsy; Evoked Potentials; Female; Fourier Analysis; Humans; Injections, Intravenous; Male; Middle Aged; Prognosis; Signal Processing, Computer-Assisted | 1993 |
In vitro inhibition of cellular immune responses by benzodiazepines and PK 11195. Effects on mitogen- and alloantigen-driven lymphocyte proliferation and on IL-1, IL-2 synthesis and IL-2 receptor expression.
Topics: Animals; B-Lymphocytes; Benzodiazepines; Benzodiazepinones; Clonazepam; Diazepam; Female; Flumazenil; Immunity, Cellular; In Vitro Techniques; Interleukin-1; Interleukin-2; Isoquinolines; Lymphocyte Activation; Male; Mice; Mice, Inbred A; Mice, Inbred C57BL; Neuroimmunomodulation; Receptors, GABA-A; T-Lymphocytes | 1993 |
Tolerance to the effects of diazepam, clonazepam and bretazenil on GABA-stimulated Cl- influx in flurazepam tolerant rats.
Topics: Animals; Benzodiazepinones; Chloride Channels; Clonazepam; Diazepam; Drug Tolerance; Flurazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Receptors, GABA | 1993 |
Hormonal modulation of benzodiazepines' actions on rat isolated uterus.
Topics: Animals; Anti-Anxiety Agents; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Drug Combinations; Estrogens; Female; Isoquinolines; Ovariectomy; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Uterine Contraction; Uterus | 1996 |
Protective effects of GABAergic drugs and other anticonvulsants in lithium-pilocarpine-induced status epilepticus.
Topics: Animals; Anticonvulsants; Baclofen; Clonazepam; Diazepam; Dizocilpine Maleate; Ethanol; GABA Agents; gamma-Aminobutyric Acid; Lithium Chloride; Male; Neuroprotective Agents; Pentobarbital; Phenobarbital; Phenytoin; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Valproic Acid | 1996 |
Simultaneous determination of twelve benzodiazepines in human serum using a new reversed-phase chromatographic column on a 2-microns porous microspherical silica gel.
Topics: Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Bromazepam; Chlordiazepoxide; Chromatography, High Pressure Liquid; Clonazepam; Diazepam; Estazolam; Humans; Linear Models; Lorazepam; Microspheres; Nitrazepam; Reproducibility of Results; Silicon Dioxide; Spectrophotometry, Ultraviolet; Triazolam | 1996 |
Catatonia after benzodiazepine withdrawal.
Topics: Aged; Aged, 80 and over; Alprazolam; Anti-Anxiety Agents; Catatonia; Clonazepam; Diazepam; Female; Humans; Male; Middle Aged; Substance Withdrawal Syndrome | 1996 |
Anticonvulsant profile of the imidazoquinazolines NNC 14-0185 and NNC 14-0189 in rats and mice.
Topics: Acoustic Stimulation; Amygdala; Animals; Anticonvulsants; Bicuculline; Carbolines; Clonazepam; Diazepam; Electroshock; Flumazenil; GABA Modulators; GABA-A Receptor Agonists; Kindling, Neurologic; Male; Mice; Mice, Inbred DBA; Mice, Inbred Strains; Pentylenetetrazole; Quinazolines; Rats; Rats, Wistar; Seizures | 1996 |
Effects of (-)-baclofen, clonazepam, and diazepam on tone exposure-induced hyperexcitability of the inferior colliculus in the rat: possible therapeutic implications for pharmacological management of tinnitus and hyperacusis.
Topics: Acoustic Stimulation; Animals; Auditory Threshold; Baclofen; Clonazepam; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Evoked Potentials, Auditory, Brain Stem; Female; GABA Modulators; Inferior Colliculi; Muscle Relaxants, Central; Neuronal Plasticity; Neurons; Olivary Nucleus; Rats; Rats, Wistar; Stereoisomerism; Tinnitus | 1996 |
Tolerance to anticonvulsant effects of some benzodiazepines in genetically epilepsy prone rats.
Topics: Acoustic Stimulation; Administration, Oral; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Cerebral Cortex; Clobazam; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Drug Tolerance; Epilepsy; Female; Injections, Intraperitoneal; Male; Motor Activity; Postural Balance; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1996 |
Memory-enhancing effects of benzodiazepines in mice.
Topics: Animals; Avoidance Learning; Benzodiazepines; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Male; Memory; Mice; Mice, Inbred Strains | 1996 |
Long-term studies on anticonvulsant tolerance and withdrawal characteristics of benzodiazepine receptor ligands in different seizure models in mice. I. Comparison of diazepam, clonazepam, clobazam and abecarnil.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbolines; Clobazam; Clonazepam; Diazepam; Drug Tolerance; GABA-A Receptor Agonists; Ligands; Male; Mice; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders | 1996 |
In vivo induction and in vitro inhibition of hepatic cytochrome P450 activity by the benzodiazepine anticonvulsants clonazepam and diazepam.
Topics: Animals; Anticonvulsants; Clonazepam; Cytochrome P-450 CYP2B1; Diazepam; Enzyme Induction; Liver; Male; Rats; Rats, Inbred F344 | 1997 |
Significant inhibition of spontaneous IgA secretion by selective peripheral-type benzodiazepine receptor ligands.
Topics: Anti-Anxiety Agents; Antibody-Producing Cells; B-Lymphocytes; Clonazepam; Diazepam; Flunitrazepam; GABA-A Receptor Antagonists; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Isoquinolines; Lymphocyte Activation | 1997 |
[Assessment of anti-tremorogenic drugs--nicotine-induced tail-tremor model].
Topics: Adrenergic beta-Antagonists; Animals; Anti-Anxiety Agents; Clonazepam; Diazepam; Disease Models, Animal; Drug Evaluation, Preclinical; Male; Mecamylamine; Nicotine; Nicotinic Antagonists; Pindolol; Propranolol; Rats; Rats, Wistar; Tail; Tremor | 1997 |
Characterization of binding sites for the omega3 receptor ligands [3H]PK11195 and [3H]RO5-4864 in human brain.
Topics: Allosteric Regulation; Benzodiazepines; Benzodiazepinones; Binding Sites; Binding, Competitive; Clonazepam; Convulsants; Detergents; Diazepam; Dithiothreitol; Female; Histidine; Humans; Isoquinolines; Ligands; Male; Occipital Lobe; Receptors, GABA-A; Sulfhydryl Reagents; Tritium | 1997 |
Modulation of intracellular calcium in human neutrophils by peripheral benzodiazepine receptor ligands.
Topics: Anti-Anxiety Agents; Benzodiazepinones; Calcium; Clonazepam; Cytosol; Diazepam; Drug Antagonism; GABA Modulators; Humans; Isoquinolines; Neutrophils; Receptors, GABA-A | 1998 |
Modulation of gamma-aminobutyric acid (GABA) receptors and the feeding response by neurosteroids in Hydra vulgaris.
Topics: Anesthetics; Animals; Anti-Anxiety Agents; Bicuculline; Carbolines; Cerebral Cortex; Chemoreceptor Cells; Clonazepam; Desoxycorticosterone; Diazepam; Feeding Behavior; GABA Antagonists; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Glutathione; Hydra; Neurotransmitter Agents; Pregnanolone; Progesterone; Pyridazines; Radioligand Assay; Rats; Receptors, GABA-A; Tritium | 1998 |
Rapid and simple chromatographic method for the determination of diazepam and its major metabolites in human plasma and urine.
Topics: Calibration; Chromatography, High Pressure Liquid; Clonazepam; Diazepam; Humans; Nordazepam; Oxazepam; Reference Values; Temazepam | 1998 |
Selection criteria and treatment of patients with disabling positional vertigo.
Topics: Audiometry; Clonazepam; Decompression, Surgical; Diazepam; Evoked Potentials, Auditory, Brain Stem; Humans; Nerve Compression Syndromes; Treatment Outcome; Vertigo; Vestibular Nerve; Vestibulocochlear Nerve | 1997 |
["Primary" orthostatic tremor. 10 clinical electrophysiologic observations].
Topics: Adult; Aged; Anti-Anxiety Agents; Arm; Clonazepam; Diazepam; Electromyography; Female; Humans; Leg; Male; Middle Aged; Muscle, Skeletal; Neurologic Examination; Phenobarbital; Posture; Primidone; Syndrome; Tremor; Weight-Bearing | 1998 |
Antiproliferative and differentiating effects of benzodiazepine receptor ligands on B16 melanoma cells.
Topics: Animals; Antineoplastic Agents; Benzodiazepinones; Cell Cycle; Cell Differentiation; Cell Division; Clonazepam; Diazepam; GABA Agents; gamma-Glutamyltransferase; Isoquinolines; Melanoma, Experimental; Mice; Nucleotides; Phenotype; Tumor Cells, Cultured | 1998 |
Plasma and CSF benzodiazepine receptor ligand concentrations in cirrhotic patients with hepatic encephalopathy: relationship to severity of encephalopathy and to pharmaceutical benzodiazepine intake.
Topics: Animals; Benzodiazepines; Binding, Competitive; Cell Fractionation; Cerebellum; Chronic Disease; Clonazepam; Diazepam; Flumazenil; GABA Modulators; Hepatic Encephalopathy; Humans; Isoquinolines; Liver Cirrhosis; Oxazepam; Radioligand Assay; Rats; Receptors, GABA-A; Tritium | 1998 |
Inhibitory regulation of amylase release in rat parotid acinar cells by benzodiazepine receptors.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Amylases; Animals; Atropine; Benzodiazepinones; Carbachol; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Flumazenil; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Isoproterenol; Male; Muscarinic Agonists; Muscarinic Antagonists; Parotid Gland; Propranolol; Rats; Rats, Wistar; Receptors, GABA-A | 1998 |
Effect of benzodiazepines and neurosteroids on ammonia-induced swelling in cultured astrocytes.
Topics: Ammonia; Astrocytes; Atrial Natriuretic Factor; Benzodiazepines; Benzodiazepinones; Brain Edema; Cell Size; Clonazepam; Dehydroepiandrosterone Sulfate; Desoxycorticosterone; Diazepam; Diazepam Binding Inhibitor; Flumazenil; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Isoquinolines; Nerve Tissue Proteins; Neuropeptides; Peptide Fragments; Pregnanolone; Pregnenolone; Protoporphyrins; Receptors, GABA-A; Steroids; Up-Regulation | 1998 |
Cardiac effects of benzodiazepine receptor agonists and antagonists in the isolated rat heart: a comparative study.
Topics: Animals; Benzodiazepines; Cardiac Output; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Female; Flumazenil; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Heart; In Vitro Techniques; Isoquinolines; Myocardial Contraction; Perfusion; Pyridines; Rats; Receptors, GABA-A; Zolpidem | 1998 |
Benzodiazepine receptor agonists modulate thymocyte apoptosis through reduction of the mitochondrial transmembrane potential.
Topics: Animals; Apoptosis; Benzodiazepines; Benzodiazepinones; Binding Sites; Caspase Inhibitors; Cells, Cultured; Clonazepam; Dexamethasone; Diazepam; Drug Interactions; Drug Synergism; Etoposide; GABA-A Receptor Agonists; Male; Membrane Potentials; Mice; Mice, Inbred BALB C; Mitochondria; Protease Inhibitors; Protein Biosynthesis; Proteins; RNA, Messenger; Thymus Gland | 1999 |
Single- and repeated-dose local toxicity in the nasal cavity of rabbits after intranasal administration of different glycols for formulations containing benzodiazepines.
Topics: Administration, Intranasal; Animals; Anti-Anxiety Agents; Benzodiazepines; Chemistry, Pharmaceutical; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Drug Evaluation; Flunitrazepam; Lorazepam; Nasal Cavity; Pharmaceutic Aids; Polyethylene Glycols; Rabbits; Time Factors | 1999 |
Central and peripheral benzodiazepine ligands prevent mitochondrial damage induced by noise exposure in the rat myocardium: an ultrastructural study.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Clonazepam; Diazepam; GABA Modulators; Isoquinolines; Male; Microscopy, Electron; Microscopy, Electron, Scanning; Mitochondria, Heart; Myocardium; Noise; Rats; Rats, Wistar; Time Factors | 1999 |
Abecarnil enhances recovery from diazepam tolerance.
Topics: Animals; Anticonvulsants; Benzodiazepines; Bicuculline; Carbolines; Cell Membrane; Cerebral Cortex; Clonazepam; Diazepam; Drug Interactions; Drug Tolerance; Flumazenil; Imidazoles; Ligands; Male; Mice; Receptors, GABA-A; Seizures; Tritium | 1999 |
Peripheral benzodiazepine receptor agonists exhibit potent antiapoptotic activities.
Topics: Apoptosis; Benzodiazepinones; Clonazepam; Diazepam; Flunitrazepam; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Humans; Isoquinolines; Jurkat Cells; Kinetics; Ligands; Receptors, GABA-A; Transfection; Tumor Necrosis Factor-alpha; U937 Cells | 1999 |
Rapid-onset intranasal delivery of anticonvulsants: pharmacokinetic and pharmacodynamic evaluation in rabbits.
Topics: Absorption; Administration, Intranasal; Animals; Anticonvulsants; Area Under Curve; Biological Availability; Carbamates; Chromatography, High Pressure Liquid; Clonazepam; Diazepam; Half-Life; Injections, Intravenous; Nasal Mucosa; Pharmaceutical Vehicles; Rabbits; Solvents | 2000 |
The treatment of sedative-hypnotic dependence: evaluating clinical predictors of outcome.
Topics: Adult; Alcoholism; Benzodiazepines; Clonazepam; Combined Modality Therapy; Comorbidity; Diazepam; Drug Administration Schedule; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Prognosis; Prospective Studies; Psychiatric Status Rating Scales; Psychotherapy; Substance Abuse Detection; Substance-Related Disorders; Treatment Outcome | 2000 |
Effects of antiepileptic drugs on rat platelet aggregation: ex vivo and in vitro study.
Topics: Animals; Anticonvulsants; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Malondialdehyde; Osmolar Concentration; Platelet Aggregation; Rats; Rats, Wistar | 2001 |
Evaluation of native GABA(A) receptors containing an alpha 5 subunit.
Topics: Alkynes; Animals; Anti-Anxiety Agents; Anticonvulsants; Autoradiography; Benzodiazepines; Cerebellum; Clobazam; Clonazepam; Diazepam; Flumazenil; Flunitrazepam; GABA-A Receptor Agonists; Hippocampus; Imidazoles; Male; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 2001 |
[Acquired pendular nystagmus associated with the lesion of tegmentum mesencephali in a patient with probable multiple sclerosis].
Topics: Adult; Brain Diseases; Clonazepam; Diazepam; Female; gamma-Aminobutyric Acid; Humans; Multiple Sclerosis; Neurons; Nystagmus, Pathologic; Tegmentum Mesencephali | 2000 |
Sensitivity to the effects of sedative-hypnotics on motor performance: influence of task difficulty and chronic phenobarbital administration.
Topics: Amobarbital; Animals; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Hypnotics and Sedatives; Male; Motor Activity; Motor Skills; Pentobarbital; Phenobarbital; Rats; Substance-Related Disorders | 2001 |
Infantile status epilepticus in Tunisia. Clinical, etiological and prognostic aspects.
Topics: Anticonvulsants; Central Nervous System Infections; Chi-Square Distribution; Child, Preschool; Clonazepam; Diazepam; Drug Therapy, Combination; Female; Fever; Follow-Up Studies; Humans; Infant; Male; Phenobarbital; Prognosis; Retrospective Studies; Status Epilepticus; Thiopental; Treatment Outcome; Tunisia | 2001 |
Diazepam inhibits HIV-1 Tat-induced migration of human microglia.
Topics: Adjuvants, Immunologic; Benzodiazepinones; Calcium Signaling; Chemotaxis; Clonazepam; Diazepam; Gene Products, tat; HIV-1; Humans; Microglia; Nerve Tissue Proteins; Receptors, CCR5; Receptors, GABA-A; tat Gene Products, Human Immunodeficiency Virus; Up-Regulation | 2001 |
Effect of diazepam and clonazepam on the function of isolated rat platelet and neutrophil.
Topics: Adenosine Diphosphate; Alprostadil; Animals; Arachidonic Acid; Blood Platelets; Calcium Signaling; Clonazepam; Diazepam; Drug Interactions; Isoquinolines; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Platelet Activation; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, GABA-A; Respiratory Burst; Thrombin | 2002 |
Reversal of benzodiazepine-induced renal vasculature relaxation with flumazenil.
Topics: Animals; Clonazepam; Diazepam; Flumazenil; GABA Modulators; Male; Muscle Relaxants, Central; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Wistar; Renal Circulation; Vasoconstrictor Agents | 2002 |
Prediction of benzodiazepines solubility using different cosolvency models.
Topics: Anti-Anxiety Agents; Benzodiazepines; Chlordiazepoxide; Clonazepam; Diazepam; Lorazepam; Models, Chemical; Predictive Value of Tests; Solubility; Solvents | 2002 |
[A common emergency in childhood. Febrile convulsions -- what to do?].
Topics: Acetaminophen; Administration, Rectal; Age Factors; Analgesics, Non-Narcotic; Anticonvulsants; Clonazepam; Diagnosis, Differential; Diazepam; Female; Humans; Hypnotics and Sedatives; Infant; Midazolam; Recurrence; Seizures, Febrile; Time Factors | 2003 |
Levetiracetam has no significant gamma-aminobutyric acid-related effect on paired-pulse interaction in the dentate gyrus of rats.
Topics: Animals; Anticonvulsants; Baclofen; Bicuculline; Clonazepam; Convulsants; Dentate Gyrus; Diazepam; Electric Stimulation; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Levetiracetam; Male; Phenobarbital; Piracetam; Rats; Rats, Sprague-Dawley; Receptors, GABA; Synaptic Transmission; Time Factors | 2003 |
Spectrophotometric and fluorimetric determination of diazepam, bromazepam and clonazepam in pharmaceutical and urine samples.
Topics: Anti-Anxiety Agents; Anticonvulsants; Bromazepam; Calibration; Chromatography, High Pressure Liquid; Clonazepam; Diazepam; Humans; Hydroxides; Light; Pharmaceutical Preparations; Potassium Compounds; Spectrometry, Fluorescence; Spectrophotometry; Urine | 2004 |
Agonist and antagonist effects of benzodiazepines on motor performance: influence of intrinsic efficacy and task difficulty.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Clonazepam; Diazepam; Drug Interactions; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Male; Motor Activity; Rats; Rats, Long-Evans | 2004 |
[Dietary supplements--surprise pills?].
Topics: Adult; Clonazepam; Diazepam; Dietary Supplements; Drug Interactions; Ephedrine; Female; Humans; Plant Extracts; Risk Factors | 2005 |
[Epileptic seizures during childbirth in a patient with idiopathic generalised epilepsy].
Topics: Adult; Anticonvulsants; Cesarean Section; Clonazepam; Diazepam; Epilepsy; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Female; Humans; Lamotrigine; Midazolam; Obstetric Labor Complications; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Triazines | 2005 |
Post-anoxic myoclonus: a case presentation and review of management in the rehabilitation setting.
Topics: Anticonvulsants; Clonazepam; Diazepam; Female; Heart Arrest; Humans; Hypoxia, Brain; Isoxazoles; Levetiracetam; Middle Aged; Myoclonus; Phenobarbital; Piracetam; Valproic Acid; Zonisamide | 2006 |
The detection of sedatives in hair and nail samples using tandem LC-MS-MS.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Azabicyclo Compounds; Benzodiazepines; Chromatography, Liquid; Clobazam; Clonazepam; Diazepam; Female; Forensic Pathology; Hair; Humans; Hypnotics and Sedatives; Male; Mass Spectrometry; Midazolam; Middle Aged; Nails; Oxazepam; Piperazines; Predictive Value of Tests; Rape; Temazepam; Triazolam | 2007 |
[Vestibular neuritis: Anti-vertigo drugs at most for three days!].
Topics: Antiemetics; Clonazepam; Diazepam; Dimenhydrinate; GABA Modulators; Glucocorticoids; Histamine H1 Antagonists; Humans; Methylprednisolone; Time Factors; Vestibular Neuronitis | 2006 |
[Epilepsy: which therapy in acute care?].
Topics: Acute Disease; Anticonvulsants; Benzodiazepines; Clobazam; Clonazepam; Diazepam; Epilepsy; Humans; Lorazepam; Treatment Outcome | 2006 |
Characterization of two classes of benzodiazepine binding sites in Schistosoma mansoni.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Binding Sites; Clonazepam; Diazepam; Flunitrazepam; GABA Agonists; GABA Modulators; Inhibitory Concentration 50; Isoquinolines; Ligands; Male; Pyridines; Rats; Rats, Wistar; Receptors, GABA-A; Schistosoma mansoni; Synaptosomes; Temperature; Time Factors; Tritium; Zolpidem | 2007 |
Influence of incorporation methods on partitioning behavior of lipophilic drugs into various phases of a parenteral lipid emulsion.
Topics: Alprazolam; Benzodiazepines; Chemistry, Pharmaceutical; Clonazepam; Diazepam; Drug Carriers; Drug Compounding; Fat Emulsions, Intravenous; Hydrogen-Ion Concentration; Lorazepam; Molecular Structure; Particle Size; Phospholipids; Solubility; Soybean Oil; Technology, Pharmaceutical; Ultracentrifugation | 2008 |
Allosteric modulation by benzodiazepines of GABA-gated chloride channels of an identified insect motor neurone.
Topics: Animals; Benzodiazepines; Benzodiazepinones; Chloride Channels; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Evoked Potentials; GABA Modulators; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Insect Proteins; Male; Membrane Potentials; Microelectrodes; Motor Neurons; Periplaneta | 2009 |
Co-operative effect between gamma-aminobutyric acid A receptors and central-type benzodiazepine receptors on amylase release in rat parotid acinar cells.
Topics: Amylases; Animals; Bicuculline; Clonazepam; Diazepam; Isoproterenol; Male; Muscimol; Parotid Gland; Rats; Rats, Wistar; Receptors, GABA-A | 2010 |
Comparison of treatment modalities in burning mouth syndrome.
Topics: Anxiety; Burning Mouth Syndrome; Chi-Square Distribution; Clonazepam; Depression; Diazepam; Female; GABA Modulators; Humans; Male; Personality Inventory; Retrospective Studies; Statistics, Nonparametric; Surveys and Questionnaires | 2009 |
Solubility prediction of drugs in mixed solvents using partial solubility parameters.
Topics: Clonazepam; Computer Simulation; Diazepam; Ethanol; Ibuprofen; Kinetics; Lamotrigine; Models, Molecular; Numerical Analysis, Computer-Assisted; Pharmaceutical Preparations; Phenobarbital; Propylene Glycol; Solubility; Solvents; Technology, Pharmaceutical; Temperature; Triazines; Water | 2011 |
[Factors associated with benzodiazepine prescription by local health services in Coronel Fabriciano, Minas Gerais State, Brazil].
Topics: Age Factors; Anti-Anxiety Agents; Brazil; Clonazepam; Cross-Sectional Studies; Diazepam; Drug Interactions; Drug Prescriptions; Female; Health Services; Humans; Male; Middle Aged; Sex Factors; Socioeconomic Factors | 2011 |
Monitoring of benzodiazepine diversion using a multi-indicator approach.
Topics: Benzodiazepines; Clonazepam; Cross-Sectional Studies; Data Collection; Databases, Factual; Diazepam; Flunitrazepam; Humans; Prescription Drugs; Principal Component Analysis; Substance-Related Disorders | 2011 |
Dependence of the kinetic and thermodynamic parameters on hydrophilic-lipophilic character of alprazolam, clonazepam, diazepam, doxepin and haloperidol in alkaline environment.
Topics: Alprazolam; Clonazepam; Diazepam; Doxepin; Drug Stability; Haloperidol; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kinetics; Thermodynamics | 2013 |
A new chemiluminescence method for determination of clonazepam and diazepam based on 1-Ethyl-3-Methylimidazolium Ethylsulfate/copper as catalyst.
Topics: Buffers; Calibration; Catalysis; Clonazepam; Copper; Diazepam; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Imidazoles; Luminescent Measurements | 2014 |
Prospects of using benzodiazepines in complex therapy of poisonings with anticholinesterase agents.
Topics: Animals; Atropine; Benzodiazepines; Cholinesterase Inhibitors; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Injections, Intramuscular; Male; Mice; Midazolam; Oximes; Pyridinium Compounds; Statistics, Nonparametric; Toxicity Tests | 2013 |
Interaction of injectable neurotropic drugs with the red cell membrane.
Topics: Central Nervous System Agents; Chlorpromazine; Citalopram; Clomipramine; Clonazepam; Diazepam; Erythrocytes; Humans; Injections; Levetiracetam; Microscopy, Electron, Scanning; Neurotransmitter Agents; Phenobarbital; Phenytoin; Piracetam; Valproic Acid | 2014 |
Influence of procedural variables on rat inhibitory avoidance and escape behaviors generated by the elevated T-maze.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Clonazepam; Diazepam; Escape Reaction; Handling, Psychological; Male; Maze Learning; Models, Psychological; Motor Activity; Rats; Rats, Wistar | 2014 |
Production of monoclonal antibody against clonazepam for immunoassay of benzodiazepine drugs in swine tissues.
Topics: Animals; Antibodies, Monoclonal; Benzodiazepines; Clonazepam; Diazepam; Drug Residues; Flunitrazepam; Food Contamination; Haptens; Immunoassay; Kidney; Limit of Detection; Liver; Meat; Mice; Mice, Inbred BALB C; Muscles; Oxazepam; Serum Albumin; Swine; Tissue Distribution | 2015 |
Detection Times of Diazepam, Clonazepam, and Alprazolam in Oral Fluid Collected From Patients Admitted to Detoxification, After High and Repeated Drug Intake.
Topics: Adult; Alprazolam; Chromatography, High Pressure Liquid; Clonazepam; Diazepam; Female; Humans; Male; Middle Aged; Saliva; Substance Abuse Detection; Substance-Related Disorders; Tandem Mass Spectrometry; Time Factors; Young Adult | 2015 |
Biosynthesis of human diazepam and clonazepam metabolites.
Topics: Anticonvulsants; Beauveria; Chaetomium; Clonazepam; Cunninghamella; Diazepam; Fungi; Humans; Hydrolysis; Hydroxylation; Industrial Microbiology; Methylation; Rhizopus | 2015 |
Is long-term use of benzodiazepine a risk for cancer?
Topics: Benzodiazepines; Carcinogens; Case-Control Studies; Chlordiazepoxide; Clonazepam; Diazepam; Female; Humans; Logistic Models; Longitudinal Studies; Male; Medazepam; Middle Aged; Nitrazepam; Oxazepam; Proportional Hazards Models | 2015 |
Development of an ultra-high-performance liquid chromatography coupled to high-resolution quadrupole-Orbitrap mass spectrometry method for the rapid detection and confirmation of illegal adulterated sedative-hypnotics in dietary supplements.
Topics: Alprazolam; Chromatography, High Pressure Liquid; Clonazepam; Diazepam; Dietary Supplements; Drug Contamination; Food Safety; Humans; Hypnotics and Sedatives; Limit of Detection; Reproducibility of Results; Tandem Mass Spectrometry | 2015 |
New benzodiazepine and Z-hypnotic users and disability pension: an eight-year nationwide observational follow-up study.
Topics: Adult; Benzodiazepines; Clonazepam; Diazepam; Disabled Persons; Drug Prescriptions; Female; Follow-Up Studies; Humans; Hypnotics and Sedatives; Male; Middle Aged; Norway; Pensions; Regression Analysis; Risk Factors; Substance-Related Disorders | 2017 |
Performance Comparison Between Monolithic, Core-Shell, and Totally Porous Particulate Columns for Application in Greener and Faster Chromatography.
Topics: Bromazepam; Chromatography, High Pressure Liquid; Clonazepam; Diazepam; Formates; Green Chemistry Technology; Parabens; Permeability; Porosity; Pressure | 2018 |
Successful treatment of refractory dermal pain with etizolam and clonazepam in a patient with acquired idiopathic generalized anhidrosis.
Topics: Adult; Biopsy; Clonazepam; Diazepam; Drug Resistance; Drug Therapy, Combination; Gabapentin; Glucocorticoids; Histamine Antagonists; Humans; Hypohidrosis; Male; Pain; Pain Measurement; Skin; Treatment Outcome; Urticaria | 2019 |
Development and Validation of an Analytical Method for the Detection and Quantification of Bromazepam, Clonazepam and Diazepam by UPLC-MS/MS in Surface Water.
Topics: Anti-Anxiety Agents; Bromazepam; Chromatography, Liquid; Clonazepam; Diazepam; Fresh Water; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Water Pollutants, Chemical | 2019 |
Seizure Rescue Medication Use among US Pediatric Epilepsy Providers: A Survey of the Pediatric Epilepsy Research Consortium.
Topics: Administration, Intranasal; Administration, Oral; Administration, Rectal; Adolescent; Age Factors; Anticonvulsants; Child; Child, Preschool; Clonazepam; Developmental Disabilities; Diazepam; Humans; Infant; Midazolam; Neurology; Pediatrics; Practice Patterns, Physicians'; Status Epilepticus; Surveys and Questionnaires | 2019 |
Diagnostic evaluation and management of seizures and status epilepticus in children with known epilepsy or new-onset seizures: A retrospective and comparative analysis.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Clonazepam; Diazepam; Epilepsy; Female; Hospitalization; Humans; Infant; Male; Phenytoin; Retrospective Studies; Seizures; Status Epilepticus | 2020 |
Spasms and Myoclonus in a Young Woman With Hashimoto Thyroiditis.
Topics: Adult; Anticonvulsants; Clonazepam; Diazepam; Encephalomyelitis; Female; Hashimoto Disease; Humans; Immunoglobulins, Intravenous; Immunologic Factors; Muscle Rigidity; Myoclonus; Prednisolone; Spasm | 2020 |
Acute chloroquine poisoning: A comprehensive experimental toxicology assessment of the role of diazepam.
Topics: Animals; Arrhythmias, Cardiac; Benzodiazepinones; Cardiotoxicity; Chloroquine; Clonazepam; Coronavirus Infections; COVID-19; Diazepam; Dose-Response Relationship, Drug; Drug Overdose; Electrocardiography; Female; Hypokalemia; Male; Pandemics; Pneumonia, Viral; Rabbits; Random Allocation; Rats; Rats, Wistar | 2020 |
Postmortem Analysis of Benzodiazepines in Human Bone by Gas Chromatography-Mass Spectrometry.
Topics: Alprazolam; Autopsy; Benzodiazepines; Chromatography, Liquid; Clonazepam; Diazepam; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Liquid-Liquid Extraction; Lorazepam; Nordazepam; Oxazepam; Tandem Mass Spectrometry | 2021 |
Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis associated with anticonvulsants in a Japanese population: Matched case-control and cohort studies.
Topics: Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Clonazepam; Cohort Studies; Diazepam; Female; Humans; Incidence; Japan; Lamotrigine; Levetiracetam; Logistic Models; Male; Middle Aged; Odds Ratio; Phenytoin; Risk Factors; Stevens-Johnson Syndrome | 2021 |
High-Dose Benzodiazepines Positively Modulate GABA
Topics: Animals; Animals, Outbred Strains; Benzodiazepines; Clonazepam; Diazepam; Female; Flumazenil; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mice; Midazolam; Receptors, GABA-A; Xenopus laevis | 2021 |
Suitability of SoToxa® Oral Fluid Screening Over Time: Re-Examination of Drugged Driving in Wisconsin.
Topics: Amphetamine; Analgesics, Opioid; Benzodiazepines; Clonazepam; Cocaine; Diazepam; Dronabinol; Fentanyl; Humans; Methamphetamine; Reproducibility of Results; Saliva; Substance Abuse Detection; Wisconsin | 2022 |
Occurrence of Z-drugs, benzodiazepines, and ketamine in wastewater in the United States and Mexico during the Covid-19 pandemic.
Topics: Alprazolam; Benzodiazepines; Clonazepam; COVID-19; Diazepam; Humans; Ketamine; Lorazepam; Mexico; Nordazepam; Pandemics; Tandem Mass Spectrometry; Temazepam; United States; Wastewater; Zolpidem | 2023 |
Repositioning of Benzodiazepine Drugs and Synergistic Effect with Ciprofloxacin Against ESKAPE Pathogens.
Topics: Anti-Bacterial Agents; Benzodiazepines; Ciprofloxacin; Clonazepam; Diazepam; Drug Repositioning | 2023 |
Insights from molecular dynamics and DFT calculations into the interaction of 1,4-benzodiazepines with 2-hydroxypropyl-βCD in a theoretical study.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Benzodiazepines; Clonazepam; Density Functional Theory; Diazepam; Molecular Dynamics Simulation; Solubility | 2023 |
Utilization of Antiseizure Medications in Women of Childbearing Age With Epilepsy and Nonepilepsy Indications: A Retrospective Cohort Study.
Topics: Anticonvulsants; Clonazepam; Diazepam; Epilepsy; Female; Gabapentin; Humans; Lamotrigine; Lorazepam; Retrospective Studies; Topiramate; Valproic Acid | 2023 |