diazepam and cl 218872

diazepam has been researched along with cl 218872 in 36 studies

Research

Studies (36)

Timeframe	Studies, this research(%)	All Research%
pre-1990	25 (69.44)	18.7374
1990's	7 (19.44)	18.2507
2000's	4 (11.11)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Barone, D; Corsico, N; Gallico, L; Luzzani, F; Occelli, E; Tarzia, G; Toja, E	1
Barone, D; Gallico, L; Luzzani, F; Tarzia, G; Toja, E	1
Albright, JD; Beer, B; Collins, JB; Greenblatt, EN; Lippa, AS; Moran, DB; Wright, WB	1
Lüddens, H; Wieland, HA	1
Cook, JM; Dayer, CA; He, X; Huang, Q; Liu, R; Ma, C; McKernan, R; Wenger, GR; Yu, S	1
Atack, JR; Carling, RW; Castro, JL; Cook, SM; Dawson, GR; Ferris, P; Isted, C; Leeson, PD; McKernan, RM; Moore, KW; O'Connor, D; Quirk, K; Street, LJ; Thomas, S; Thompson, SA; Wafford, KA; Wild, D	1
Atack, JR; Bromidge, FA; Carling, RW; Castro, JL; Cook, SM; Hunt, P; Isted, C; Lucas, M; Macaulay, AJ; McKernan, RM; Mitchinson, A; Moore, KW; Narquizian, R; Russell, MG; Thomas, D; Thompson, SA; Wafford, KA	1
McNamara, RK; Skelton, RW	1
Franklin, SR; Tang, AH	1
De Luca, C; De Medici, D; Massotti, M	1
Lüddens, H; Pritchett, DB; Seeburg, PH	1
Arbilla, S; Langer, SZ; Lista, A	1
De Medici, D; Gatta, F; Longo, VG; Massotti, M	1
Bennett, DA	1
Spealman, RD; Wettstein, JG	1
Komiskey, HL	1
Spealman, RD	1
Cole, R; De Vellis, J; Noble, EP; Syapin, PJ	1
Meiners, BA; Salama, AI	1
Sieghart, W	1
Bates, JF; Hall, TW; Peake, L; Standish, LJ; Swearengen, ES	1
Morin, AM	1
Gerhardt, S; Liebman, JM; Prowse, J	1
Gee, KW; Morelli, M; Yamamura, HI	1
Jones, BJ; Oakley, NR; Straughan, DW	1
Fukuda, H; Goto, M; Saito, K	1
Gluckman, PD; Taylor, KM; Villiger, JW	2
Brinton, RE; Gee, KW; Yamamura, HI	1
Vellucci, SV; Webster, RA	1
Squires, RF	1
Garrett, KM; Melchior, CL; Tabakoff, B	1
Blaney, FE; Edge, C; Phippen, RW	1
Akaike, N; Hirata, A; Munakata, M; Shirasaki, T; Yakushiji, T	1
Aguayo, LG; Cisternas, C; Pancetti, FC; Tapia, JC	1
Safo, P; Thompson, SA; Wafford, KA; Wheat, L; Whiting, PJ; Wingrove, PB	1

Reviews

1 review(s) available for diazepam and cl 218872

Article	Year
Benzodiazepine receptor multiplicity. Neuropharmacology, 1983, Volume: 22, Issue:12B Topics: Animals; Brain; Diazepam; Flunitrazepam; gamma-Aminobutyric Acid; Humans; Pyridazines; Receptors, Cell Surface; Receptors, GABA-A	1983

Other Studies

35 other study(ies) available for diazepam and cl 218872

Article	Year
6-(Alkylamino)-3-aryl-1,2,4-triazolo[3,4-a]phthalazines. A new class of benzodiazepine receptor ligands. Journal of medicinal chemistry, 1988, Volume: 31, Issue:6 Topics: Aggression; Animals; Anticonvulsants; Conflict, Psychological; In Vitro Techniques; Ligands; Macaca; Male; Mice; Motor Activity; Rats; Rats, Inbred Strains; Receptors, GABA-A; Species Specificity; Structure-Activity Relationship	1988
Benzodiazepine receptor binding and anticonflict activity in a series of 3,6-disubstituted pyridazino[4,3-c]isoquinolines devoid of anticonvulsant properties. Journal of medicinal chemistry, 1985, Volume: 28, Issue:9 Topics: Animals; Binding, Competitive; Chemical Phenomena; Chemistry; Conflict, Psychological; Diazepam; Isoquinolines; Male; Mice; Pyridazines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Structure-Activity Relationship	1985
Synthesis and anxiolytic activity of 6-(substituted-phenyl)-1,2,4-triazolo[4,3-b]pyridazines. Journal of medicinal chemistry, 1981, Volume: 24, Issue:5 Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Antihypertensive Agents; Binding, Competitive; Chemical Phenomena; Chemistry; Conflict, Psychological; Diazepam; Male; Pyridazines; Rats; Triazoles	1981
Four amino acid exchanges convert a diazepam-insensitive, inverse agonist-preferring GABAA receptor into a diazepam-preferring GABAA receptor. Journal of medicinal chemistry, 1994, Dec-23, Volume: 37, Issue:26 Topics: Amino Acid Sequence; Azides; Base Sequence; Benzodiazepines; Binding Sites; Diazepam; GABA Agonists; Humans; Molecular Sequence Data; Mutation; Receptors, GABA-A; Structure-Activity Relationship	1994
Pharmacophore/receptor models for GABA(A)/BzR subtypes (alpha1beta3gamma2, alpha5beta3gamma2, and alpha6beta3gamma2) via a comprehensive ligand-mapping approach. Journal of medicinal chemistry, 2000, Jan-13, Volume: 43, Issue:1 Topics: Animals; Benzodiazepines; Carbolines; Cell Line; Columbidae; Conditioning, Operant; Crystallography, X-Ray; Humans; Indoles; Ligands; Male; Models, Molecular; Pyrimidines; Quinolones; Radioligand Assay; Receptors, GABA-A; Saimiri; Stereoisomerism; Structure-Activity Relationship	2000
3-phenyl-6-(2-pyridyl)methyloxy-1,2,4-triazolo[3,4-a]phthalazines and analogues: high-affinity gamma-aminobutyric acid-A benzodiazepine receptor ligands with alpha 2, alpha 3, and alpha 5-subtype binding selectivity over alpha 1. Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7 Topics: Animals; Anti-Anxiety Agents; Binding, Competitive; Biological Availability; Cell Line; GABA-A Receptor Agonists; Humans; Magnetic Resonance Spectroscopy; Maze Learning; Oocytes; Patch-Clamp Techniques; Phthalazines; Radioligand Assay; Rats; Receptors, GABA-A; Recombinant Proteins; Structure-Activity Relationship; Triazoles; Xenopus	2004
Discovery of functionally selective 7,8,9,10-tetrahydro-7,10-ethano-1,2,4-triazolo[3,4-a]phthalazines as GABA A receptor agonists at the alpha3 subunit. Journal of medicinal chemistry, 2005, Mar-10, Volume: 48, Issue:5 Topics: Animals; Binding Sites; Cell Line; Female; GABA-A Receptor Agonists; Humans; Models, Molecular; Oocytes; Patch-Clamp Techniques; Phthalazines; Protein Subunits; Radioligand Assay; Receptors, GABA-A; Structure-Activity Relationship; Triazoles; Xenopus laevis	2005
Like diazepam, CL 218,872, a selective ligand for the benzodiazepine omega 1 receptor subtype, impairs place learning in the Morris water maze. Psychopharmacology, 1992, Volume: 107, Issue:2-3 Topics: Animals; Anti-Anxiety Agents; Diazepam; Flumazenil; Learning; Male; Memory; Motor Activity; Pyridazines; Rats; Receptors, GABA-A	1992
The discriminative stimulus effects of diazepam in rats at two training doses. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 258, Issue:3 Topics: Alprazolam; Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Buspirone; Carbolines; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Flumazenil; Male; Morphine; Pentobarbital; Pyrazoles; Pyridazines; Rats; Rats, Inbred Strains; Triazolam	1991
Relative efficacies of benzodiazepine receptor agonists in affecting red nucleus electrical activity in rabbits. Psychopharmacology, 1990, Volume: 102, Issue:4 Topics: Animals; Bicuculline; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Flunitrazepam; Imidazoles; Isoquinolines; Male; Pentylenetetrazole; Pyridazines; Pyridines; Rabbits; Receptors, GABA-A; Red Nucleus; Zolpidem	1990
Type I and type II GABAA-benzodiazepine receptors produced in transfected cells. Science (New York, N.Y.), 1989, Sep-22, Volume: 245, Issue:4924 Topics: Cell Line; Diazepam; Flumazenil; Flunitrazepam; Humans; Molecular Weight; Pyridazines; Receptors, GABA-A; Recombinant Proteins; Transfection	1989
Modulation of the electrically evoked release of 5-[3H]hydroxytryptamine from rat cerebral cortex: effects of alpidem, CL 218872, and diazepam. Journal of neurochemistry, 1988, Volume: 51, Issue:5 Topics: Animals; Benzodiazepines; Carbolines; Cerebral Cortex; Diazepam; Electric Stimulation; Flumazenil; gamma-Aminobutyric Acid; Imidazoles; Male; Monoamine Oxidase Inhibitors; Pargyline; Pyrazoles; Pyridazines; Pyridines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Serotonin	1988
Effects of drugs on the electrical activity of the red nucleus in the rabbit. Activation of benzodiazepine and barbiturate receptors. Annali dell'Istituto superiore di sanita, 1988, Volume: 24, Issue:3 Topics: Animals; Bicuculline; Carbolines; Diazepam; Drug Interactions; Electroencephalography; Flumazenil; Muscle Relaxation; Pentobarbital; Pyridazines; Rabbits; Receptors, GABA-A; Receptors, Neurotransmitter; Red Nucleus	1988
The non-sedating anxiolytic CGS 9896 produces discriminative stimuli that may be related to an anxioselective effect. Life sciences, 1985, Aug-26, Volume: 37, Issue:8 Topics: Animals; Anti-Anxiety Agents; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Meprobamate; Pyrazoles; Pyridazines; Rats; Rats, Inbred Strains	1985
Behavioral effects of zopiclone, CL 218,872 and diazepam in squirrel monkeys: antagonism by Ro 15-1788 and CGS 8216. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:2 Topics: Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Benzodiazepinones; Conditioning, Operant; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Male; Piperazines; Pyrazoles; Pyridazines; Saimiri	1986
Aging: effect on ex-vivo benzodiazepine binding after a diazepam injection. Neurochemical research, 1987, Volume: 12, Issue:8 Topics: Aging; Animals; Anti-Anxiety Agents; Binding, Competitive; Brain; Diazepam; Flunitrazepam; Kinetics; Male; Pyridazines; Rats; Rats, Inbred F344; Receptors, GABA-A	1987
Discriminative-stimulus effects of midazolam in squirrel monkeys: comparison with other drugs and antagonism by Ro 15-1788. The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:2 Topics: Animals; Azabicyclo Compounds; Barbital; Benzodiazepines; Benzodiazepinones; Buspirone; Caffeine; Chlordiazepoxide; Cinanserin; Clozapine; Conditioning, Operant; Cyproheptadine; Diazepam; Diphenhydramine; Discrimination Learning; Electroshock; Flumazenil; Male; Midazolam; Muscimol; Nordazepam; Pentobarbital; Piperazines; Pyridazines; Pyrimidines; Saimiri; Tripelennamine	1985
Benzodiazepine binding characteristics of embryonic rat brain neurons grown in culture. Journal of neurochemistry, 1985, Volume: 45, Issue:6 Topics: Animals; Benzodiazepines; Benzodiazepinones; Brain; Carbolines; Cells, Cultured; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Flumazenil; gamma-Aminobutyric Acid; Neurons; Pyridazines; Rats; Receptors, GABA-A	1985
Enhancement of GABA binding by the benzodiazepine partial agonist CGS9896. European journal of pharmacology, 1985, Dec-10, Volume: 119, Issue:1-2 Topics: Animals; Benzodiazepines; Benzodiazepinones; Brain; Calcium Chloride; Diazepam; Flumazenil; gamma-Aminobutyric Acid; In Vitro Techniques; Magnesium; Pyrazoles; Pyridazines; Rats; Receptors, GABA-A	1985
Comparison of benzodiazepine receptors in cerebellum and inferior colliculus. Journal of neurochemistry, 1986, Volume: 47, Issue:3 Topics: Aging; Animals; Animals, Newborn; Carbolines; Cell Membrane; Cerebellum; Clonazepam; Diazepam; Flunitrazepam; Inferior Colliculi; Pyridazines; Rats; Receptors, GABA-A	1986
CL 218-872 pretreatment and intervention block kainate-induced convulsions and neuropathology. Behavioral neuroscience, 1988, Volume: 102, Issue:1 Topics: Animals; Anticonvulsants; Brain; Diazepam; Kainic Acid; Male; Organ Specificity; Pyridazines; Rats; Rats, Inbred Strains; Seizures	1988
Beta-carboline kindling of the benzodiazepine receptor. Brain research, 1984, Oct-29, Volume: 321, Issue:1 Topics: Animals; Benzodiazepinones; Carbolines; Convulsants; Diazepam; Flumazenil; Indoles; Kindling, Neurologic; Pyridazines; Rats; Rats, Inbred Strains; Receptors, GABA-A	1984
Anxiolytic drugs selectively increase preferred duration of rewarding brain stimulation in a shuttlebox test. Pharmacology, biochemistry, and behavior, 1982, Volume: 16, Issue:5 Topics: Animals; Anti-Anxiety Agents; Apomorphine; Brain; Chlordiazepoxide; Diazepam; Male; Pentobarbital; Pyridazines; Rats; Rats, Inbred F344; Reaction Time; Reward; Self Stimulation	1982
The effect of temperature on CL 218872 and propyl beta-carboline-3-carboxylate inhibition of [3H]-flunitrazepam binding in rat brain. Biochemical and biophysical research communications, 1982, Apr-29, Volume: 105, Issue:4 Topics: Animals; Anti-Anxiety Agents; Binding Sites; Carbolines; Cerebral Cortex; Diazepam; Flunitrazepam; Hippocampus; Indoles; Kinetics; Male; Pyridazines; Rats; Rats, Inbred Strains	1982
The benzodiazepine receptor ligand CL218,872 has both anxiolytic and sedative properties in rodents. Neuropharmacology, 1984, Volume: 23, Issue:7A Topics: Aggression; Animals; Anti-Anxiety Agents; Arousal; Brain; Diazepam; Dose-Response Relationship, Drug; Flunitrazepam; Humans; Male; Mice; Mice, Inbred Strains; Motor Activity; Motor Skills; Pyridazines; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A	1984
Effects of pentobarbital on [3H]diazepam binding in the cerebral cortex, cerebellum and spinal cord of developing rats. Japanese journal of pharmacology, 1984, Volume: 36, Issue:2 Topics: Aging; Animals; Anti-Anxiety Agents; Cerebellum; Cerebral Cortex; Diazepam; Female; In Vitro Techniques; Male; Pentobarbital; Pyridazines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spinal Cord	1984
Characteristics of type 1 and type 2 benzodiazepine receptors in the ovine brain. Pharmacology, biochemistry, and behavior, 1982, Volume: 16, Issue:3 Topics: Animals; Binding, Competitive; Brain; Diazepam; Female; gamma-Aminobutyric Acid; Kinetics; Membranes; Pregnancy; Pyridazines; Receptors, Drug; Receptors, GABA-A; Sheep	1982
CL 218872 antagonism of diazepam induced loss of righting reflex: evidence for partial agonistic activity at the benzodiazepine receptor. Life sciences, 1983, Feb-28, Volume: 32, Issue:9 Topics: Animals; Anticonvulsants; Diazepam; Drug Synergism; Male; Mice; Posture; Pyridazines; Receptors, Cell Surface; Receptors, GABA-A; Reflex	1983
Multiple benzodiazepine receptors in the ovine brain: ontogenesis, properties, and distribution of 3H-diazepam binding. Pediatric pharmacology (New York, N.Y.), 1982, Volume: 2, Issue:3 Topics: Animals; Brain Chemistry; Diazepam; Female; Fetus; Frontal Lobe; gamma-Aminobutyric Acid; Pyridazines; Receptors, Cell Surface; Receptors, GABA-A; Sheep; Tritium	1982
Is Ro15-1788 a partial agonist at benzodiazepine receptors? European journal of pharmacology, 1983, Jun-03, Volume: 90, Issue:2-3 Topics: Animals; Benzodiazepinones; Bicuculline; Convulsants; Diazepam; Flumazenil; Male; Mice; Mice, Inbred C3H; Phenobarbital; Pyridazines; Receptors, Cell Surface; Receptors, GABA-A	1983
A benzodiazepine antagonist action of CL 218,872. Life sciences, 1984, May-28, Volume: 34, Issue:22 Topics: Animals; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Convulsants; Diazepam; Flumazenil; Male; Mice; Mice, Inbred C57BL; Pyridazines; Receptors, Cell Surface; Receptors, GABA-A; Seizures	1984
Molecular surface comparison. 2. Similarity of electrostatic vector fields in drug design. Journal of molecular graphics, 1995, Volume: 13, Issue:3 Topics: Anti-Anxiety Agents; Benzamides; Benzazepines; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Diazepam; Drug Design; Electricity; GABA-A Receptor Agonists; Granisetron; Indoles; Isomerism; Molecular Conformation; Ondansetron; Pharmaceutical Preparations; Protein Binding; Pyrazoles; Pyridazines; Receptors, Drug; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Structure-Activity Relationship; Surface Properties; Triazolam; Tropisetron	1995
Differential properties of type I and type II benzodiazepine receptors in mammalian CNS neurones. British journal of pharmacology, 1993, Volume: 109, Issue:3 Topics: Aging; Animals; Benzothiepins; Central Nervous System; Cerebral Cortex; Diazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Neurons; Purkinje Cells; Pyridazines; Rats; Rats, Wistar; Receptors, GABA-A; Spinal Cord; Tranquilizing Agents	1993
Effects of benzodiazepine receptor ligands on isolated rat superior cervical ganglia neurons. Pharmacology, 1996, Volume: 52, Issue:6 Topics: Age Factors; Animals; Animals, Newborn; Anti-Anxiety Agents; Diazepam; Electrophysiology; Flumazenil; gamma-Aminobutyric Acid; Ligands; Neurons; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Superior Cervical Ganglion	1996
Mechanism of alpha-subunit selectivity of benzodiazepine pharmacology at gamma-aminobutyric acid type A receptors. European journal of pharmacology, 2002, Feb-15, Volume: 437, Issue:1-2 Topics: Animals; Anti-Anxiety Agents; Binding, Competitive; Cell Line; Diazepam; Dose-Response Relationship, Drug; Female; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Humans; Membrane Potentials; Mutation; Oocytes; Protein Subunits; Pyridazines; Pyridines; Radioligand Assay; Receptors, GABA-A; Tritium; Xenopus laevis; Zolpidem	2002