diazepam and captopril

diazepam has been researched along with captopril in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19902 (10.00)18.7374
1990's1 (5.00)18.2507
2000's9 (45.00)29.6817
2010's8 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Axe, FU; Bembenek, SD; Butler, CR; Coles, F; Dunford, PJ; Edwards, JP; Fourie, AM; Grice, CA; Karlsson, L; Lundeen, K; Riley, JP; Savall, BM; Tays, KL; Wei, J; Williams, KN; Xue, X1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Costall, B; Domeney, AM; Gerrard, PA; Horovitz, ZP; Kelly, ME; Naylor, RJ; Tomkins, DM1
Perry, DC1
Ramos, OL; Ribeiro, AB; Saragoça, M1
Cincikas, D; Ivaskevicius, J1
Albuquerque, Mde F; Lima, SG; Nascimento, LS; Santos Filho, CN; Victor, EG1
Grossman, E; Nadler, M; Shachar, A; Shamiss, A; Sharabi, Y; Thaler, M1
Tandeter, H1

Reviews

1 review(s) available for diazepam and captopril

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

3 trial(s) available for diazepam and captopril

ArticleYear
[Hypertensive crisis. Treatment with captopril after failure with a diuretic. Multicenter study].
    Arquivos brasileiros de cardiologia, 1982, Volume: 38, Issue:5

    Topics: Administration, Oral; Adult; Blood Pressure; Captopril; Clinical Trials as Topic; Diazepam; Drug Therapy, Combination; Emergencies; Female; Furosemide; Humans; Hypertension; Male; Middle Aged; Proline

1982
[Systemic hypertension at emergency units. The use of symptomatic drugs as choice for management].
    Arquivos brasileiros de cardiologia, 2005, Volume: 85, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure Determination; Captopril; Diazepam; Dipyrone; Emergency Treatment; Female; Headache; Humans; Hypertension; Male; Middle Aged; Obesity; Patient Compliance; Treatment Outcome

2005
Antianxiety treatment in patients with excessive hypertension.
    American journal of hypertension, 2005, Volume: 18, Issue:9 Pt 1

    Topics: Administration, Oral; Administration, Sublingual; Adult; Aged; Aged, 80 and over; Anti-Anxiety Agents; Antihypertensive Agents; Blood Pressure; Captopril; Diazepam; Female; Humans; Hypertension; Male; Middle Aged; Treatment Outcome

2005

Other Studies

16 other study(ies) available for diazepam and captopril

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity.
    Journal of medicinal chemistry, 2008, Jul-24, Volume: 51, Issue:14

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Catalysis; Dogs; Drug Evaluation, Preclinical; Enzyme Inhibitors; Epoxide Hydrolases; Humans; Magnetic Resonance Spectroscopy; Mice; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Effects of captopril and SQ29,852 on anxiety-related behaviours in rodent and marmoset.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 36, Issue:1

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anxiety; Behavior, Animal; Callitrichinae; Captopril; Diazepam; Drug Interactions; Female; Male; Mice; Organophosphorus Compounds; Proline; Rats; Species Specificity; Substance Withdrawal Syndrome

1990
Barrel rotation in rats induced by intracerebroventricular bradykinin antagonists.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 28, Issue:1

    Topics: Animals; Atropine; Bradykinin; Captopril; Diazepam; Dose-Response Relationship, Drug; Haloperidol; Injections, Intraventricular; Male; Motor Activity; Muscimol; Naloxone; Phenobarbital; Phenytoin; Posture; Rats; Rats, Inbred Strains; Structure-Activity Relationship

1987
Application of controlled arterial hypotension in endoscopic rhinosurgery.
    Medicina (Kaunas, Lithuania), 2003, Volume: 39, Issue:9

    Topics: Adjuvants, Anesthesia; Adolescent; Adult; Anesthesia; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Loss, Surgical; Captopril; Data Interpretation, Statistical; Diazepam; Endoscopy; Female; Humans; Hypotension, Controlled; Male; Middle Aged; Nasal Polyps; Nitroglycerin; Nose; Paranasal Sinuses; Time Factors; Vasodilator Agents

2003
Hypothesis: A single dose of an anxiolitic may prevent unnecessary visits to the emergency room during blood pressure elevations.
    Medical hypotheses, 2016, Volume: 88

    Topics: Aged; Alprazolam; Anti-Anxiety Agents; Antihypertensive Agents; Autonomic Nervous System Diseases; Blood Pressure; Blood Pressure Determination; Calcium Channel Blockers; Captopril; Diazepam; Emergency Medicine; Emergency Service, Hospital; Humans; Hypertension; Models, Theoretical; Risk

2016