diazepam and amantadine

diazepam has been researched along with amantadine in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199011 (39.29)18.7374
1990's1 (3.57)18.2507
2000's8 (28.57)29.6817
2010's6 (21.43)24.3611
2020's2 (7.14)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Ahman, M; Holmén, AG; Wan, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Glen, RC; Lowe, R; Mitchell, JB1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bonezzi, C; Mapelli, A; Pagani, I1
DeDonato, A; Lucca, GP; Montanari, C1
Calne, DB1
Becker, H; Bittkau, S; Przuntek, H; Schröder, J; Sczesni, B; Truong, DD; von Baumgarten, F1
Gulda, O; Sulcová, A2
Sanford, TJ; Smith, NT; Weinger, MB1
Kumar, V1
Lazarus, A1
Flechter, S; Graff, E; Oberman, Z; Rabey, JM; Vardi, J1
Candelise, L; Faglioni, P; Spinnler, H; Vignolo, LA1
Decobert, M; Depoortere, H; Honoré, L1
Anderson, CA; Arciniegas, DB; Brousseau, KM; Frey, KL; Harris, SN1
Garg, C; Garg, M; Walia, V1
Gücüyener, K; Karaduman, AE; Menderes, DK; Özbudak, P; Öztürk, H1

Reviews

3 review(s) available for diazepam and amantadine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Drug treatment of spasticity and rigidity.
    Modern trends in neurology, 1975, Volume: 6

    Topics: Amantadine; Baclofen; Diazepam; Humans; Levodopa; Mephenesin; Muscle Rigidity; Parasympatholytics; Phenols; Phenothiazines; Spasm; Spinal Nerve Roots

1975
Drug effects on the EEG of various species of laboratory animals.
    Neuropsychobiology, 1983, Volume: 9, Issue:4

    Topics: 5-Hydroxytryptophan; Amantadine; Animals; Antihypertensive Agents; Azabicyclo Compounds; Brain; Cats; Chlormethiazole; Clonidine; Diazepam; Electroencephalography; Flunitrazepam; Guanabenz; Guanfacine; Guanidines; Imidazoles; Male; Nitrazepam; Pentobarbital; Phenylacetates; Piperazines; Piracetam; Rats; Sodium Oxybate; Yohimbine

1983

Trials

2 trial(s) available for diazepam and amantadine

ArticleYear
Ketamine induction and amantadine.
    The British journal of clinical practice, 1975, Volume: 29, Issue:1

    Topics: Adult; Amantadine; Anesthesia, General; Blood Pressure; Clinical Trials as Topic; Diazepam; Female; Humans; Ketamine; Male; Middle Aged; Psychophysiology; Respiration

1975
Letter: Treatment of Huntington's chorea.
    The New England journal of medicine, 1973, Nov-29, Volume: 289, Issue:22

    Topics: Amantadine; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Clinical Trials as Topic; Diazepam; Dihydroxyphenylalanine; Drug Therapy, Combination; Haloperidol; Humans; Huntington Disease; Hydrazines; Reserpine

1973

Other Studies

23 other study(ies) available for diazepam and amantadine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
[Action of amantadine on arousal from balanced diazepam-ketamine anesthesia in patients undergoing angiographic examinations].
    Minerva anestesiologica, 1976, Volume: 42, Issue:9

    Topics: Amantadine; Anesthesia, General; Angiography; Aortography; Diazepam; Humans; Ketamine

1976
[Diagnostic and therapeutic aspects of neuroleptic malignant syndrome based on 12 cases].
    Wiener klinische Wochenschrift, 1991, Volume: 103, Issue:1

    Topics: Adult; Amantadine; Antipsychotic Agents; Bromocriptine; Dantrolene; Depressive Disorder; Diazepam; Drug Therapy, Combination; Female; Humans; Intellectual Disability; Lisuride; Male; Middle Aged; Neuroleptic Malignant Syndrome; Psychotic Disorders; Schizophrenia

1991
The behavioural effects of benzodiazepine receptor ligands in mice are inhibited by adamantylamide dipeptide.
    Activitas nervosa superior, 1989, Volume: 31, Issue:4

    Topics: Adjuvants, Immunologic; Amantadine; Animals; Anxiety; Behavior, Animal; Carbolines; Diazepam; Dipeptides; Male; Mice; Receptors, GABA-A

1989
The immunomodulators levamisole, muramyl dipeptide and adamantylamide dipeptide antagonize the antianxiety effect of diazepam.
    Activitas nervosa superior, 1989, Volume: 31, Issue:2

    Topics: Acetylmuramyl-Alanyl-Isoglutamine; Aggression; Agonistic Behavior; Amantadine; Animals; Anti-Anxiety Agents; Diazepam; Dipeptides; Immune System; Levamisole; Male; Mice

1989
Do dopaminergic drugs really prevent opiate-induced rigidity?
    Anesthesia and analgesia, 1988, Volume: 67, Issue:9

    Topics: Amantadine; Diazepam; Dopamine; Humans; Muscle Rigidity; Narcotics

1988
A case of neuroleptic malignant syndrome treated with diazepam.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1987, Volume: 32, Issue:9

    Topics: Aged; Amantadine; Diazepam; Humans; Male; Neuroleptic Malignant Syndrome; Substance Withdrawal Syndrome

1987
Therapy of neuroleptic malignant syndrome.
    Psychiatric developments, 1986,Spring, Volume: 4, Issue:1

    Topics: Amantadine; Bromocriptine; Carbidopa; Combined Modality Therapy; Dantrolene; Diazepam; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroconvulsive Therapy; Humans; Levodopa; Neuroleptic Malignant Syndrome; Receptors, Dopamine

1986
Selective regional effect of various neuroactive drugs on bromocriptine concentration in the brain of rats.
    Acta neurologica Scandinavica, 1986, Volume: 74, Issue:4

    Topics: Amantadine; Animals; Biperiden; Brain Chemistry; Bromocriptine; Carbidopa; Diazepam; Haloperidol; Levodopa; Methysergide; Naloxone; Rats

1986
Amantadine for neurobehavioural deficits following delayed post-hypoxic encephalopathy.
    Brain injury, 2004, Volume: 18, Issue:12

    Topics: Adult; Amantadine; Brain; Brain Injuries; Cognition Disorders; Demyelinating Diseases; Diazepam; Dopamine Agents; Humans; Hypnotics and Sedatives; Hypoxia-Ischemia, Brain; Magnetic Resonance Imaging; Male; Mental Disorders; Methadone; Narcotics

2004
Amantadine exerts anxiolytic like effect in mice: Evidences for the involvement of nitrergic and GABAergic signaling pathways.
    Behavioural brain research, 2020, 02-17, Volume: 380

    Topics: Amantadine; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Brain; Diazepam; Disease Models, Animal; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Glutamic Acid; Male; Mice; Nitric Oxide; Nitrites; Receptors, N-Methyl-D-Aspartate; Signal Transduction

2020
Celiac disease and catatonia: more than a coincidence?
    The Turkish journal of pediatrics, 2023, Volume: 65, Issue:1

    Topics: Adolescent; Amantadine; Biopsy; Catatonia; Celiac Disease; Child; Diazepam; Female; Humans

2023