diazepam has been researched along with 6-methyl-2-(phenylethynyl)pyridine in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (75.00) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Balázs, O; Balogh, GT; Béni, Z; Bielik, A; Bobok, A; Domány, G; Gál, K; Galambos, J; Greiner, I; Halász, AS; Keserű, GM; Kolok, S; Kóti, J; Krasavin, M; Laszy, J; Mikó-Bakk, ML; Nógrádi, K; Orgován, Z; Sághy, K; Szakács, Z; Szombathelyi, Z; Vastag, M; Wágner, G | 1 |
| Chojnacka-Wójcik, E; Gasparini, F; Klodzińska, A; Kuhn, R; Palucha, A; Pilc, A; Tatarczyńska, E | 1 |
| Gasparini, F; Gentsch, C; Kuhn, R; Schoeffter, P; Spooren, WP | 1 |
| Brodkin, J; Busse, C; Sukoff, SJ; Varney, MA | 1 |
| Besheer, J; Hodge, CW | 1 |
| Cryan, JF; Gasparini, F; Page, ME; Szeliga, P | 1 |
| Ballard, TM; Huwyler, J; Porter, R; Prinssen, E; Spooren, W; Woolley, ML | 1 |
| Kolb, Y; Nicolas, LB; Prinssen, EP | 1 |
| Chen, PM; Lee, WL; Tang, FR; Tang, YC; Tsai, MC | 1 |
| George, SA; Hutson, PH; Stephens, DN | 1 |
| Arndt, SS; Boleij, H; Jaeschke, G; Kirchhoff, S; Lindemann, L; Nordquist, RE; Ohl, F; Pinzon, NE; Salomons, AR; Spooren, W | 1 |
| Chaki, S; Fukumoto, K; Iijima, M | 1 |
12 other study(ies) available for diazepam and 6-methyl-2-(phenylethynyl)pyridine
| Article | Year |
|---|---|
Discovery and Preclinical Characterization of 3-((4-(4-Chlorophenyl)-7-fluoroquinoline-3-yl)sulfonyl)benzonitrile, a Novel Non-acetylenic Metabotropic Glutamate Receptor 5 (mGluR5) Negative Allosteric Modulator for Psychiatric Indications.
Topics: Allosteric Regulation; Animals; Anti-Anxiety Agents; Dogs; Female; Halogenation; Humans; Macaca fascicularis; Male; Maze Learning; Molecular Docking Simulation; Nitriles; Quinolines; Rats; Receptor, Metabotropic Glutamate 5 | 2017 |
Potential anxiolytic- and antidepressant-like effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist.
Topics: 5-Hydroxytryptophan; Animals; Anti-Anxiety Agents; Antidepressive Agents; Behavior, Animal; Diazepam; Dose-Response Relationship, Drug; Drinking; Drinking Behavior; Imipramine; Male; Maze Learning; Mice; Mice, Inbred C57BL; Psychomotor Performance; Pyridines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate | 2001 |
Pharmacological and endocrinological characterisation of stress-induced hyperthermia in singly housed mice using classical and candidate anxiolytics (LY314582, MPEP and NKP608).
Topics: Adrenocorticotropic Hormone; Analysis of Variance; Animals; Anti-Anxiety Agents; Benzodiazepines; Body Temperature; Bridged Bicyclo Compounds; Buspirone; Chlordiazepoxide; Clobazam; Corticosterone; Diazepam; Ethanol; Hyperthermia, Induced; Male; Mice; Mice, Inbred ICR; Oxazepam; Piperidines; Pyridines; Quinolines; Reproducibility of Results; Stress, Physiological | 2002 |
Anxiolytic-like activity of the mGluR5 antagonist MPEP: a comparison with diazepam and buspirone.
Topics: Animals; Anti-Anxiety Agents; Buspirone; Diazepam; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fear; GABA-A Receptor Agonists; Male; Punishment; Pyridines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reflex, Startle; Vocalization, Animal | 2002 |
Pharmacological and anatomical evidence for an interaction between mGluR5- and GABA(A) alpha1-containing receptors in the discriminative stimulus effects of ethanol.
Topics: Alcoholism; Animals; Diazepam; Discrimination, Psychological; Disease Models, Animal; Drug Interactions; Ethanol; Excitatory Amino Acid Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Glutamic Acid; Immunohistochemistry; Male; Neurons; Pentobarbital; Pyridines; Rats; Rats, Long-Evans; Receptor, Metabotropic Glutamate 5; Receptors, GABA-A; Receptors, Metabotropic Glutamate; Synaptic Transmission; Telencephalon | 2005 |
Blockade of the mGlu5 receptor decreases basal and stress-induced cortical norepinephrine in rodents.
Topics: Animals; Diazepam; Excitatory Amino Acid Antagonists; Frontal Lobe; Male; Microdialysis; Norepinephrine; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Stress, Psychological; Thiazoles | 2005 |
The effect of the mGlu5 receptor antagonist MPEP in rodent tests of anxiety and cognition: a comparison.
Topics: Animals; Anxiety; Brain; Choice Behavior; Cognition; Conditioning, Psychological; Conflict, Psychological; Diazepam; Excitatory Amino Acid Antagonists; Fear; Male; Maze Learning; Pyridines; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate | 2005 |
A combined marble burying-locomotor activity test in mice: a practical screening test with sensitivity to different classes of anxiolytics and antidepressants.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Behavior, Animal; Diazepam; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Fluoxetine; Haloperidol; Imidazoles; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred CBA; Morphine; Motor Activity; Obsessive-Compulsive Disorder; Pyridines; Reproducibility of Results; Species Specificity; Spiro Compounds | 2006 |
Two-methyl-6-phenylethynyl-pyridine (MPEP), a metabotropic glutamate receptor 5 antagonist, with low doses of MK801 and diazepam: a novel approach for controlling status epilepticus.
Topics: Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Diazepam; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Excitatory Amino Acid Antagonists; GABA Modulators; Male; Mice; Oxazines; Pilocarpine; Pyridines; Status Epilepticus | 2007 |
Differential effects of MPEP and diazepam in tests of conditioned emotional response and Pavlovian-to-instrumental transfer suggests 'anxiolytic' effects are mediated by different mechanisms.
Topics: Animals; Anti-Anxiety Agents; Conditioning, Operant; Cues; Diazepam; Dose-Response Relationship, Drug; Emotions; Excitatory Amino Acid Antagonists; Food; Habituation, Psychophysiologic; Male; Motivation; Pyridines; Rats; Receptors, Kainic Acid | 2009 |
Differential effects of diazepam and MPEP on habituation and neuro-behavioural processes in inbred mice.
Topics: Animals; Avoidance Learning; Diazepam; Habituation, Psychophysiologic; Male; Mice; Mice, 129 Strain; Mice, Inbred BALB C; Mice, Inbred Strains; Pyridines; Random Allocation | 2012 |
Acute and sustained effects of a metabotropic glutamate 5 receptor antagonist in the novelty-suppressed feeding test.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Carbazoles; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Inhibitors; Exploratory Behavior; Feeding Behavior; Fluvoxamine; Immunosuppressive Agents; Indole Alkaloids; Inhibition, Psychological; Male; Mice; Mice, Inbred C57BL; Pyridines; Reaction Time; Sirolimus; Time Factors | 2012 |