diaminopimelic acid and n(2)-(gamma-d-glutamyl)-meso-2,2'-diaminopimelic acid

diaminopimelic acid has been researched along with n(2)-(gamma-d-glutamyl)-meso-2,2'-diaminopimelic acid in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19902 (4.76)18.7374
1990's0 (0.00)18.2507
2000's4 (9.52)29.6817
2010's27 (64.29)24.3611
2020's9 (21.43)2.80

Authors

AuthorsStudies
Hashimoto, M; Hemmi, K; Kitaura, Y; Nakaguchi, O; Okada, S; Takeno, H; Yonishi, S1
Hashimoto, M; Hemmi, K; Kitaura, Y; Mine, Y; Mori, J; Nakaguchi, O; Okada, S; Senoh, H; Takeno, H; Yonishi, S1
Breukink, E; Fujimoto, Y; Fukase, K; Hasegawa, M; Inohara, N; Kawasaki, A; Masumoto, J; Nuñez, G; Yang, K1
Abrahams, VM; Cardenas, I; Guller, S; Mulla, MJ; Panda, B; Yu, AG1
Girardin, SE; Lee, J; Philpott, DJ; Tattoli, I; Vavricka, SR; Wojtal, KA1
Hirao, K; Matsuo, T; Mukai, K; Nakanishi, T; Takahashi, K; Yumoto, H1
Agnihotri, G; Balakrishna, R; David, SA; Malladi, SS; Ukani, R; Wang, X; Warshakoon, HJ1
Huang, DM; Li, XY; Tang, L; Wang, Q; Wang, Y; Zhang, L; Zhou, XD1
Abrahams, VM; Cardenas, I; Guller, S; Mulla, MJ; Myrtolli, K; Norwitz, ER; Sfakianaki, AK; Tadesse, S1
Cardell, LO; Kvarnhammar, AM; Petterson, T1
Frentsch, M; Lendlein, A; Mathew, S; Roch, T; Wischke, C2
Li, Y; Song, YL; Zhou, H; Zhou, YJ1
Saito, Y; Takahata, H; Wakamatsu, H; Yoshimura, Y1
Chu, IM; Chu, YJ; Dong, J; He, L; Hu, S; Lam, CW; Leung, KM; Liu, KY; Qiu, HN; Wong, CK1
Basu, M; Bej, A; Dikhit, MR; Jayasankar, P; Sahoo, BR; Samanta, M; Swain, B1
Duan, J; Liu, J; Ouyang, X; Wang, Y1
Basu, M; Samanta, M; Swain, B1
Guan, L; Liu, S; Peng, B; Xing, A; Xiong, Q; Yu, P; Zhou, S1
Gobec, M; Hazdovac, T; Jakopin, Ž; Kodela, J; Mlinarič-Raščan, I; Sollner Dolenc, M1
Abrahams, VM; Guller, S; Gysler, SM; Han, CS; Hoang, M; Norwitz, ER; Potter, JA1
Lappas, M; Lim, R1
Behera, BK; Bej, A; Bhoi, GK; Dehury, B; Lenka, SK; Maharana, J; Patra, MC; Rout, AK; Sahoo, BR; Sahoo, JR1
Hirao, K; Matsuo, T; Nakanishi, T; Takahashi, K; Takegawa, D; Yumoto, H1
Bailey, AG; Bushman, FD; Clarke, TB; Hergott, CB; Laughlin, A; Roche, AM; Tamashiro, E; Weiser, JN1
Agra, N; Benito, G; Boscá, L; Delgado, C; Fernández-Velasco, M; González-Peramato, P; Gonzalez-Ramos, S; Martín-Sanz, P; Pacheco, I; Prieto, P; Terrón, V; Val-Blasco, A; Vallejo-Cremades, MT1
Bi, D; Chu, Q; Cui, J; Gao, Y; Xu, T1
Chandra Roy, A; Chang, G; Dai, H; Roy, S; Shen, X; Wang, Y; Zhang, H1
Bilal, MS; Dai, H; Ma, N; Roy, AC; Shen, X; Wang, L; Wang, Y; Zhang, W1
Griffin, ME; Hang, HC; Wang, YC; Westcott, NP1
Aabdin, ZU; Chang, G; Liu, J; Ma, N; Roy, AC; Roy, S; Shen, X; Wang, Y1
Kuriyama, S; Takano, M; Takeuchi, T; Yumoto, R1
Fu, S; Li, C; Liang, P; Liu, M; Song, Y; Wang, Z; Yang, C; Zhang, J; Zhang, Y1
Bauer, D; Busch, M; Heiligenhaus, A; Jalilvand, TV; Kasper, M; Laffer, B; Langmann, T; Thanos, S; Wasmuth, S1
Chang, G; Dai, H; Gao, Q; Ma, N; Roy, AC; Shen, X; Shi, X; Wang, Y1
Chang, G; Cheng, X; Gao, Q; Huang, J; Liu, J; Roy, AC; Shen, X; Wang, Y1
Coleman, DN; Dai, H; Hu, L; Loor, JJ; Lopes, MG; Martinez-Cortés, I; Parys, C; Shen, X1
Aabdin, ZU; Cheng, X; Dai, H; Ma, N; Shen, X; Shi, X; Wang, Y1
Chang, G; Gao, Q; Ma, N; Roy, AC; Roy, S; Shen, X1
Chuphal, B; Kumar, R; Rai, U; Roy, B1
Cabaña-Brunod, M; Duarte, Y; Fuentes, JA; González-Nilo, D; Herrera, PA; Llancalahuen, FM; Márquez-Miranda, V; Otero, C; Velásquez, L; Vilos, C1
Anonick, MV; Bharadwaj, R; Brown, A; Grimes, CL; Jaiswal, S; Mashayekh, S; Okuda, K; Silverman, N; Wodzanowski, KA1

Other Studies

42 other study(ies) available for diaminopimelic acid and n(2)-(gamma-d-glutamyl)-meso-2,2'-diaminopimelic acid

ArticleYear
Studies on structure-activity relationships of FK-156, an immunostimulating peptide, and related compounds. II. Synthesis of N2-(gamma-D-glutamyl)-2(L), 2'(D)-diaminopimelic acid as the minimal essential structure of FK-156.
    Chemical & pharmaceutical bulletin, 1984, Volume: 32, Issue:8

    Topics: Adjuvants, Immunologic; Amino Acids, Diamino; Animals; Diaminopimelic Acid; Mice; Structure-Activity Relationship

1984
N2-(gamma-D-Glutamyl)-meso-2(L),2'(D)-diaminopimelic acid as the minimal prerequisite structure of FK-156: its acyl derivatives with potent immunostimulating activity.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:4

    Topics: Adjuvants, Immunologic; Amino Acids, Diamino; Animals; Diaminopimelic Acid; Female; Guinea Pigs; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Structure-Activity Relationship

1982
A role of lipophilic peptidoglycan-related molecules in induction of Nod1-mediated immune responses.
    The Journal of biological chemistry, 2007, Apr-20, Volume: 282, Issue:16

    Topics: Adaptor Proteins, Signal Transducing; Animals; Bacterial Proteins; Cell Line; Diaminopimelic Acid; Escherichia coli; Humans; Immune System; Ligands; Mice; Mice, Inbred BALB C; Mice, Transgenic; Models, Chemical; Nod1 Signaling Adaptor Protein; Peptidoglycan; Stereoisomerism

2007
Regulation of Nod1 and Nod2 in first trimester trophoblast cells.
    American journal of reproductive immunology (New York, N.Y. : 1989), 2009, Volume: 61, Issue:4

    Topics: Apoptosis; Benzamides; Cells, Cultured; Cytokines; Diaminopimelic Acid; Female; Gene Expression Regulation, Developmental; Humans; Lipopolysaccharides; NF-kappa B; Nod1 Signaling Adaptor Protein; Nod2 Signaling Adaptor Protein; Pregnancy; Pregnancy Trimester, First; Sequence Deletion; Signal Transduction; Thiazoles; Toll-Like Receptor 4; Transgenes; Trophoblasts

2009
pH-dependent internalization of muramyl peptides from early endosomes enables Nod1 and Nod2 signaling.
    The Journal of biological chemistry, 2009, Aug-28, Volume: 284, Issue:35

    Topics: Acetylmuramyl-Alanyl-Isoglutamine; Biological Transport; Carrier Proteins; Cell Line; Diaminopimelic Acid; Endocytosis; Endosomes; Humans; Hydrogen-Ion Concentration; Inflammatory Bowel Diseases; Ligands; Membrane Transport Proteins; Nerve Tissue Proteins; Nod1 Signaling Adaptor Protein; Nod2 Signaling Adaptor Protein; Protein Binding

2009
Roles of TLR2, TLR4, NOD2, and NOD1 in pulp fibroblasts.
    Journal of dental research, 2009, Volume: 88, Issue:8

    Topics: Acetylmuramyl-Alanyl-Isoglutamine; Apoptosis; Cells, Cultured; Chemokine CCL2; Chemokine CXCL10; Cyclooxygenase 2; Dental Pulp; Diaminopimelic Acid; Dinoprostone; Escherichia coli; Fibroblasts; Humans; Inflammation Mediators; Interleukin-6; Interleukin-8; Lipopeptides; Lipopolysaccharides; Nod1 Signaling Adaptor Protein; Nod2 Signaling Adaptor Protein; Pulpitis; Signal Transduction; Streptococcus mutans; Toll-Like Receptor 2; Toll-Like Receptor 4; Vascular Cell Adhesion Molecule-1

2009
Structure-activity relationships in nucleotide oligomerization domain 1 (Nod1) agonistic γ-glutamyldiaminopimelic acid derivatives.
    Journal of medicinal chemistry, 2011, Mar-10, Volume: 54, Issue:5

    Topics: Adjuvants, Immunologic; CD11b Antigen; Diaminopimelic Acid; Gene Expression Profiling; HEK293 Cells; Humans; Immunity, Innate; In Vitro Techniques; Interleukins; Leukocytes, Mononuclear; Membrane Glycoproteins; NF-kappa B; Nod1 Signaling Adaptor Protein; p38 Mitogen-Activated Protein Kinases; Receptors, Immunologic; Stereoisomerism; Structure-Activity Relationship; Triggering Receptor Expressed on Myeloid Cells-1; Up-Regulation

2011
Expression of TRAF6 and pro-inflammatory cytokines through activation of TLR2, TLR4, NOD1, and NOD2 in human periodontal ligament fibroblasts.
    Archives of oral biology, 2011, Volume: 56, Issue:10

    Topics: Apoptosis; Cell Culture Techniques; Cells, Cultured; Diaminopimelic Acid; Escherichia coli; Fibroblasts; Gene Silencing; Humans; Immunity, Innate; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Interleukin-8; Interleukins; Lipopeptides; Lipopolysaccharides; Nod1 Signaling Adaptor Protein; Nod2 Signaling Adaptor Protein; Periodontal Ligament; RNA, Small Interfering; TNF Receptor-Associated Factor 6; Toll-Like Receptor 2; Toll-Like Receptor 4; Up-Regulation

2011
Nod1 activation by bacterial iE-DAP induces maternal-fetal inflammation and preterm labor.
    Journal of immunology (Baltimore, Md. : 1950), 2011, Jul-15, Volume: 187, Issue:2

    Topics: Animals; Animals, Newborn; Cell Line; Diaminopimelic Acid; Disease Models, Animal; Female; Humans; Infant, Newborn; Infant, Premature; Inflammation; Maternal-Fetal Exchange; Mice; Mice, Inbred C57BL; Nod1 Signaling Adaptor Protein; Obstetric Labor, Premature; Pregnancy; Pregnancy Outcome; Tissue Culture Techniques; Trophoblasts

2011
NOD-like receptors and RIG-I-like receptors in human eosinophils: activation by NOD1 and NOD2 agonists.
    Immunology, 2011, Volume: 134, Issue:3

    Topics: Acetylmuramyl-Alanyl-Isoglutamine; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Carrier Proteins; CD11b Antigen; Cell Movement; Cells, Cultured; DEAD Box Protein 58; DEAD-box RNA Helicases; Diaminopimelic Acid; Eosinophil-Derived Neurotoxin; Eosinophils; Flow Cytometry; Gene Expression; Humans; Immunohistochemistry; Interferon-Induced Helicase, IFIH1; Interleukin-8; L-Selectin; Lectins, C-Type; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Nod1 Signaling Adaptor Protein; Nod2 Signaling Adaptor Protein; Receptors, Immunologic; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction

2011
Potential of NOD receptor ligands as immunomodulators in particulate vaccine carriers.
    Journal of controlled release : official journal of the Controlled Release Society, 2012, Dec-28, Volume: 164, Issue:3

    Topics: Acetylmuramyl-Alanyl-Isoglutamine; Adjuvants, Immunologic; Cell Line, Tumor; Cell Survival; Cytokines; Dendritic Cells; Diaminopimelic Acid; Drug Carriers; Drug Compounding; Humans; Lactic Acid; Leukocytes, Mononuclear; Ligands; Nod1 Signaling Adaptor Protein; Nod2 Signaling Adaptor Protein; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties; Vaccines

2012
NOD1 activation induces innate immune responses and insulin resistance in human adipocytes.
    Diabetes & metabolism, 2012, Volume: 38, Issue:6

    Topics: Adipocytes, White; Cell Differentiation; Cells, Cultured; Cytokines; Diaminopimelic Acid; Female; Glucose; Humans; Immunity, Innate; Insulin Resistance; NF-kappa B; Nod1 Signaling Adaptor Protein; Nod2 Signaling Adaptor Protein; Obesity; Phosphorylation; RNA, Messenger; Signal Transduction

2012
Adjuvant effect of microencapsulated NOD ligands studied in a human phagocytic cell line.
    Journal of applied biomaterials & functional materials, 2012, Volume: 10, Issue:3

    Topics: Acetylmuramyl-Alanyl-Isoglutamine; Adjuvants, Immunologic; Cell Line; Diaminopimelic Acid; Drug Compounding; Emulsions; Humans; Lactic Acid; Ligands; Microspheres; Nod Signaling Adaptor Proteins; Oils; Phagocytes; Phagocytosis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vaccines, Subunit; Water

2012
A facile synthesis of fully protected meso-diaminopimelic acid (DAP) and its application to the preparation of lipophilic N-acyl iE-DAP.
    Molecules (Basel, Switzerland), 2013, Jan-16, Volume: 18, Issue:1

    Topics: Catalysis; Diaminopimelic Acid; Esterification; Hydrophobic and Hydrophilic Interactions; Nod1 Signaling Adaptor Protein; Oxidation-Reduction; Peptidoglycan

2013
NOD-like receptors mediated activation of eosinophils interacting with bronchial epithelial cells: a link between innate immunity and allergic asthma.
    Cellular & molecular immunology, 2013, Volume: 10, Issue:4

    Topics: Acetylmuramyl-Alanyl-Isoglutamine; Animals; Asthma; Bronchi; CD18 Antigens; Cell Communication; Cell Line; Chemokines; Coculture Techniques; Diaminopimelic Acid; Eosinophils; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Immunity, Innate; Intercellular Adhesion Molecule-1; Interleukin-13; Mice; NF-kappa B; Nod1 Signaling Adaptor Protein; Nod2 Signaling Adaptor Protein; Respiratory Mucosa; Th2 Cells

2013
Activation of nucleotide-binding oligomerization domain 1 (NOD1) receptor signaling in Labeo rohita by iE-DAP and identification of ligand-binding key motifs in NOD1 by molecular modeling and docking.
    Applied biochemistry and biotechnology, 2013, Volume: 170, Issue:6

    Topics: Amino Acid Motifs; Animals; Binding Sites; Computer Simulation; Cypriniformes; Diaminopimelic Acid; Ligands; Models, Biological; Models, Chemical; Models, Molecular; Nod Signaling Adaptor Proteins; Protein Binding; Signal Transduction

2013
Intracellular adhesion molecule-1 is regulated by porphyromonas gingivalis through nucleotide binding oligomerization domain-containing proteins 1 and 2 molecules in periodontal fibroblasts.
    Journal of periodontology, 2014, Volume: 85, Issue:2

    Topics: Acetylmuramyl-Alanyl-Isoglutamine; Adult; Aged; Alkaline Phosphatase; Cell Culture Techniques; Cells, Cultured; Chronic Periodontitis; Diaminopimelic Acid; Female; Fibroblasts; Gene Expression Regulation, Bacterial; Gene Knockdown Techniques; Gingiva; Humans; Intercellular Adhesion Molecule-1; Male; Middle Aged; Nod1 Signaling Adaptor Protein; Nod2 Signaling Adaptor Protein; Periodontal Ligament; Porphyromonas gingivalis; RNA Interference; RNA, Small Interfering; Up-Regulation; Young Adult

2014
NOD1 and NOD2 receptors in mrigal (Cirrhinus mrigala): inductive expression and downstream signalling in ligand stimulation and bacterial infections.
    Journal of biosciences, 2013, Volume: 38, Issue:3

    Topics: Animals; Bacterial Infections; Carps; Diaminopimelic Acid; Gene Expression Regulation; Interferon-gamma; Interleukin-1beta; Interleukin-8; Ligands; Receptors, Pattern Recognition; Signal Transduction

2013
NOD1 expression elicited by iE-DAP in first trimester human trophoblast cells and its potential role in infection-associated inflammation.
    European journal of obstetrics, gynecology, and reproductive biology, 2013, Volume: 170, Issue:2

    Topics: Cell Line; Chorioamnionitis; Diaminopimelic Acid; Female; Humans; Interleukin-6; Interleukin-8; NF-kappa B; Nod1 Signaling Adaptor Protein; Pregnancy; Pregnancy Trimester, First; Receptor-Interacting Protein Serine-Threonine Kinase 2; Signal Transduction; Trophoblasts

2013
Synthesis of conformationally constrained γ-D-glutamyl-meso-diaminopimelic acid derivatives as ligands of nucleotide-binding oligomerization domain protein 1 (Nod1).
    European journal of medicinal chemistry, 2013, Volume: 69

    Topics: Cells, Cultured; Cytokines; Diaminopimelic Acid; Dose-Response Relationship, Drug; Humans; Leukocytes, Mononuclear; Ligands; Molecular Conformation; NF-kappa B; Nod1 Signaling Adaptor Protein; Structure-Activity Relationship

2013
Human fetal membranes generate distinct cytokine profiles in response to bacterial Toll-like receptor and nod-like receptor agonists.
    Biology of reproduction, 2014, Volume: 90, Issue:2

    Topics: Cytokines; Diaminopimelic Acid; Extraembryonic Membranes; Female; Flagellin; Humans; Interleukin-1beta; Lipopolysaccharides; Nod Signaling Adaptor Proteins; Nod2 Signaling Adaptor Protein; Oligodeoxyribonucleotides; Pregnancy; Pregnancy Complications, Infectious; Toll-Like Receptors

2014
Differential expression of AP-1 proteins in human myometrium after spontaneous term labour onset.
    European journal of obstetrics, gynecology, and reproductive biology, 2014, Volume: 177

    Topics: Cell Nucleus; Cells, Cultured; Cytoplasm; Diaminopimelic Acid; Diglycerides; Female; Flagellin; Humans; Labor Onset; Lipopolysaccharides; Myometrium; Oligopeptides; Pregnancy; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; RNA, Messenger; Term Birth; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Tumor Necrosis Factor-alpha

2014
Structural and functional investigation of zebrafish (Danio rerio) NOD1 leucine rich repeat domain and its interaction with iE-DAP.
    Molecular bioSystems, 2014, Volume: 10, Issue:11

    Topics: Amino Acid Sequence; Animals; Binding Sites; Conserved Sequence; Diaminopimelic Acid; Humans; Molecular Dynamics Simulation; Nod1 Signaling Adaptor Protein; Protein Binding; Protein Structure, Secondary; Signal Transduction; Zebrafish; Zebrafish Proteins

2014
Modulatory roles of interferon-γ through indoleamine 2, 3-dioxygenase induction in innate immune response of dental pulp cells.
    Journal of endodontics, 2014, Volume: 40, Issue:9

    Topics: Acetylmuramyl-Alanyl-Isoglutamine; Adjuvants, Immunologic; Cells, Cultured; Chemokine CXCL10; Dental Pulp; Diaminopimelic Acid; Fibroblasts; Humans; Immunity, Innate; Immunologic Factors; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation Mediators; Interferon-gamma; Interleukin-6; Lipopeptides; Lipopolysaccharides; Nod1 Signaling Adaptor Protein; Nod2 Signaling Adaptor Protein; Pulpitis; Toll-Like Receptor 2; Toll-Like Receptor 4

2014
Peptidoglycan from the gut microbiota governs the lifespan of circulating phagocytes at homeostasis.
    Blood, 2016, 05-19, Volume: 127, Issue:20

    Topics: Adoptive Transfer; Animals; Animals, Congenic; Anti-Bacterial Agents; Apoptosis; Cell Survival; Diaminopimelic Acid; Female; Gastrointestinal Microbiome; Germ-Free Life; Homeostasis; Interleukin-17; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Neutrophils; Nod1 Signaling Adaptor Protein; Nod2 Signaling Adaptor Protein; Peptidoglycan; Phagocytes; Toll-Like Receptor 2; Toll-Like Receptor 4

2016
NOD1 activation in cardiac fibroblasts induces myocardial fibrosis in a murine model of type 2 diabetes.
    The Biochemical journal, 2017, 02-01, Volume: 474, Issue:3

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diaminopimelic Acid; Endomyocardial Fibrosis; Gene Expression Regulation; Humans; Insulin; Insulin Resistance; Mice; Mice, Transgenic; Myocardium; NF-kappa B; NIH 3T3 Cells; Nitriles; Nod1 Signaling Adaptor Protein; Signal Transduction; Sulfones; Transforming Growth Factor beta

2017
NOD1 is the innate immune receptor for iE-DAP and can activate NF-κB pathway in teleost fish.
    Developmental and comparative immunology, 2017, Volume: 76

    Topics: Animals; Bacterial Infections; Cells, Cultured; Diaminopimelic Acid; Fish Diseases; Fish Proteins; Immunity, Innate; Inflammation Mediators; NF-kappa B; Nod1 Signaling Adaptor Protein; Perciformes; Signal Transduction

2017
Sodium Butyrate Mitigates iE-DAP Induced Inflammation Caused by High-Concentrate Feeding in Liver of Dairy Goats.
    Journal of agricultural and food chemistry, 2018, Aug-29, Volume: 66, Issue:34

    Topics: Acidosis; Animal Feed; Animals; Butyric Acid; Chemokine CCL20; Cytokines; Diaminopimelic Acid; Goat Diseases; Goats; Liver; Liver Diseases; Rumen

2018
Overfeeding with a high-concentrate diet activates the NOD1-NF-κB signalling pathway in the mammary gland of mid-lactating dairy cows.
    Microbial pathogenesis, 2019, Volume: 128

    Topics: Acidosis; Animal Feed; Animals; Cattle; Cattle Diseases; Cytokines; Diaminopimelic Acid; Diet; Female; Gastrointestinal Tract; Gene Expression Regulation; Humans; Hydrogen-Ion Concentration; Inflammation; Interleukin-1beta; Interleukin-6; Lactation; Mammary Glands, Animal; NF-kappa B; Nod1 Signaling Adaptor Protein; Rumen; Signal Transduction; Tumor Necrosis Factor-alpha

2019
Peptidoglycan Metabolite Photoaffinity Reporters Reveal Direct Binding to Intracellular Pattern Recognition Receptors and Arf GTPases.
    ACS chemical biology, 2019, 03-15, Volume: 14, Issue:3

    Topics: Acetylmuramyl-Alanyl-Isoglutamine; ADP-Ribosylation Factors; Cell Wall; Cytokines; Diaminopimelic Acid; HEK293 Cells; Humans; Ligands; Mutant Proteins; Mutation; Nod1 Signaling Adaptor Protein; Nod2 Signaling Adaptor Protein; Peptidoglycan; Protein Binding; Receptors, Pattern Recognition; Signal Transduction; Structure-Activity Relationship

2019
Sodium butyrate suppresses NOD1-mediated inflammatory molecules expressed in bovine hepatocytes during iE-DAP and LPS treatment.
    Journal of cellular physiology, 2019, Volume: 234, Issue:11

    Topics: Animals; Butyric Acid; Cattle; Diaminopimelic Acid; Hepatocytes; Inflammation; Ligands; Lipopolysaccharides; Liver; NF-kappa B; Nod1 Signaling Adaptor Protein; Phosphorylation; Receptor-Interacting Protein Serine-Threonine Kinase 2

2019
Role of peptide transporter 2 and MAPK signaling pathways in the innate immune response induced by bacterial peptides in alveolar epithelial cells.
    Life sciences, 2019, Jul-15, Volume: 229

    Topics: A549 Cells; Alveolar Epithelial Cells; Cytokines; Diaminopimelic Acid; Humans; Immunity, Innate; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Signal Transduction; Symporters

2019
NOD1 modulates decidual stromal cell function to maintain pregnancy in the early trimester.
    Cell biochemistry and function, 2019, Volume: 37, Issue:7

    Topics: Adult; Apoptosis; Cells, Cultured; Cytokines; Decidua; Diaminopimelic Acid; Female; Humans; Nod1 Signaling Adaptor Protein; Pregnancy; Pregnancy Trimester, First; Stromal Cells

2019
Phenotypic Differences in Primary Murine Microglia Treated with NOD1, NOD2, and NOD1/2 Agonists.
    Journal of molecular neuroscience : MN, 2020, Volume: 70, Issue:4

    Topics: Acetylmuramyl-Alanyl-Isoglutamine; Adjuvants, Immunologic; Animals; Calcium-Binding Proteins; Cell Shape; Cell Surface Extensions; Cells, Cultured; Diaminopimelic Acid; Interleukin-6; Mice; Mice, Inbred C57BL; Microfilament Proteins; Microglia; Nod1 Signaling Adaptor Protein; Nod2 Signaling Adaptor Protein; Phenotype; Tumor Necrosis Factor-alpha

2020
Sodium valproate attenuates the iE-DAP induced inflammatory response by inhibiting the NOD1-NF-κB pathway and histone modifications in bovine mammary epithelial cells.
    International immunopharmacology, 2020, Volume: 83

    Topics: Acetylation; Animals; Apoptosis; Autophagy; Cattle; Cells, Cultured; Diaminopimelic Acid; Epithelial Cells; Female; Histones; Inflammation; Mastitis, Bovine; NF-kappa B; Nod1 Signaling Adaptor Protein; Protein Processing, Post-Translational; Signal Transduction; STAT1 Transcription Factor; Valproic Acid

2020
Sodium butyrate attenuated iE-DAP induced inflammatory response in the mammary glands of dairy goats fed high-concentrate diet.
    Journal of the science of food and agriculture, 2021, Volume: 101, Issue:3

    Topics: Acidosis; Animal Feed; Animals; Butyric Acid; Diaminopimelic Acid; Diet; Dietary Supplements; Female; Goat Diseases; Goats; Mammary Glands, Animal; NF-kappa B; Nod1 Signaling Adaptor Protein

2021
Alterations in immune and antioxidant gene networks by gamma-d-glutamyl-meso-diaminopimelic acid in bovine mammary epithelial cells are attenuated by in vitro supply of methionine and arginine.
    Journal of dairy science, 2021, Volume: 104, Issue:1

    Topics: Amino Acid Transport Systems; Animals; Antioxidants; Arginine; Cattle; Cells, Cultured; Diaminopimelic Acid; Epithelial Cells; Female; Gene Regulatory Networks; Immunity, Innate; Mammary Glands, Animal; Methionine; Nod1 Signaling Adaptor Protein; RNA, Messenger; Superoxide Dismutase-1

2021
Glutamine pretreatment protects bovine mammary epithelial cells from inflammation and oxidative stress induced by γ-d-glutamyl-meso-diaminopimelic acid (iE-DAP).
    Journal of dairy science, 2021, Volume: 104, Issue:2

    Topics: Animals; Apoptosis; Cattle; Cattle Diseases; Cells, Cultured; Diaminopimelic Acid; Epithelial Cells; Female; Glutamine; Heme Oxygenase-1; Inflammation; Mammary Glands, Animal; NF-kappa B; Oxidative Stress; Reactive Oxygen Species; Transcription Factor RelA

2021
γ-d-Glutamyl-meso-diaminopimelic acid induces autophagy in bovine hepatocytes during nucleotide-binding oligomerization domain 1-mediated inflammation.
    Journal of cellular physiology, 2021, Volume: 236, Issue:7

    Topics: Animals; Autophagosomes; Autophagy; Autophagy-Related Protein 5; Autophagy-Related Protein-1 Homolog; Cattle; Cell Survival; Cells, Cultured; Diaminopimelic Acid; Hepatocytes; Inflammation; Nod1 Signaling Adaptor Protein; Receptor-Interacting Protein Serine-Threonine Kinase 2; RNA Interference; RNA, Messenger; RNA, Small Interfering

2021
Molecular and functional characterization of spotted snakehead NOD1 with an emphasis on structural insights into iE-DAP binding motifs employing advanced bioinformatic tools.
    Journal of biomolecular structure & dynamics, 2022, Volume: 40, Issue:16

    Topics: Computational Biology; Diaminopimelic Acid; Leucine; Nod1 Signaling Adaptor Protein

2022
Development of a PHBV nanoparticle as a peptide vehicle for NOD1 activation.
    Drug delivery, 2021, Volume: 28, Issue:1

    Topics: Animals; Cell Survival; Chemistry, Pharmaceutical; Diaminopimelic Acid; Dose-Response Relationship, Drug; Drug Carriers; Drug Liberation; Drug Stability; Mice; Nanoparticles; Nod1 Signaling Adaptor Protein; Polyesters; RAW 264.7 Cells

2021
Synthesis and validation of click-modified NOD1/2 agonists.
    Innate immunity, 2023, Volume: 29, Issue:8

    Topics: Diaminopimelic Acid; Nod1 Signaling Adaptor Protein; Nod2 Signaling Adaptor Protein; Receptor Protein-Tyrosine Kinases

2023