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diadenosine tetraphosphate and uridine triphosphate

diadenosine tetraphosphate has been researched along with uridine triphosphate in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's3 (25.00)18.2507
2000's6 (50.00)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jacobson, KA; Jarvis, MF; Williams, M1
Hillmann, P; Höltje, HD; Ko, GY; Kostenis, E; Müller, CE; Nicholas, RA; Raulf, A; Spinrath, A; von Kügelgen, I; Wolff, SC1
Camden, J; Fischer, B; Weisman, GA; Yelovitch, S1
Flodgaard, H; Hedman, C; Winther, K1
Andersson, M; Lewan, L1
Boucher, RC; Harden, TK; Lazarowski, ER; Stutts, MJ; Watt, WC1
Bailey, SJ; Hourani, SM; Johnson, CR; Tennant, JP1
Laubinger, W; Reiser, G; Streubel, G1
Barnes, A; Boughtflower, R; Camacho, J; Cousens, D; Marshall, F; Patel, K; Paterson, C1
Bautista, A; Carracedo, G; Peral, A; Pintor, J1
Lee, SY; Müller, CE; Namasivayam, V1
Harden, TK; Herold, CL; Kennedy, C; Nicholas, RA; Qi, AD1

Reviews

1 review(s) available for diadenosine tetraphosphate and uridine triphosphate

ArticleYear
Purine and pyrimidine (P2) receptors as drug targets.
    Journal of medicinal chemistry, 2002, Sep-12, Volume: 45, Issue:19

    Topics: Adenosine Triphosphate; Animals; Drug Design; Humans; Ligands; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyrimidines; Receptors, Purinergic P2; Uridine Triphosphate

2002

Trials

1 trial(s) available for diadenosine tetraphosphate and uridine triphosphate

ArticleYear
Platelet P1, P4-Di (adenosine-51) tetraphosphate (AP4A) in migraine patients before and during beta-adrenoceptor blockade.
    European journal of clinical investigation, 1990, Volume: 20, Issue:3

    Topics: Adenosine Triphosphate; Adult; Blood Platelets; Dinucleoside Phosphates; Female; Humans; Male; Metoprolol; Migraine Disorders; Propranolol; Receptors, Adrenergic, beta; Uridine Triphosphate

1990

Other Studies

10 other study(ies) available for diadenosine tetraphosphate and uridine triphosphate

ArticleYear
Key determinants of nucleotide-activated G protein-coupled P2Y(2) receptor function revealed by chemical and pharmacological experiments, mutagenesis and homology modeling.
    Journal of medicinal chemistry, 2009, May-14, Volume: 52, Issue:9

    Topics: Amino Acid Sequence; Amino Acids; Animals; Cell Line; Disulfides; Drug Design; Enzyme-Linked Immunosorbent Assay; Extracellular Space; Gene Expression; Humans; Ligands; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleotides; Oxidation-Reduction; Protein Structure, Secondary; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Sequence Homology, Amino Acid

2009
Boranophosphate isoster controls P2Y-receptor subtype selectivity and metabolic stability of dinucleoside polyphosphate analogues.
    Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1

    Topics: Animals; Boranes; Calcium; Cell Line, Tumor; Dinucleoside Phosphates; Drug Stability; Humans; Hydrolysis; Models, Molecular; Molecular Conformation; Phosphoric Diester Hydrolases; Purinergic P2Y Receptor Agonists; Pyrophosphatases; Receptors, Purinergic P2Y; Stereoisomerism; Structure-Activity Relationship; Turkey

2012
Early increase in diadenosine tetraphosphate in regenerating rat liver.
    Experimental cell research, 1988, Volume: 175, Issue:2

    Topics: Adenine Nucleotides; Animals; Cell Division; Chromatography, High Pressure Liquid; Deoxyadenine Nucleotides; Dinucleoside Phosphates; DNA; Liver; Liver Regeneration; Male; Rats; Rats, Inbred Strains; Thymine Nucleotides; Uridine Triphosphate

1988
Pharmacological selectivity of the cloned human P2U-purinoceptor: potent activation by diadenosine tetraphosphate.
    British journal of pharmacology, 1995, Volume: 116, Issue:1

    Topics: Adenine; Adenine Nucleotides; Astrocytoma; Cloning, Molecular; Dinucleoside Phosphates; Humans; Inositol Phosphates; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Second Messenger Systems; Sensitivity and Specificity; Transfection; Tritium; Tumor Cells, Cultured; Uridine Triphosphate

1995
Effects of adenosine 5'-triphosphate, uridine 5'-triphosphate, adenosine 5'-tetraphosphate and diadenosine polyphosphates in guinea-pig taenia caeci and rat colon muscularis mucosae.
    Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 358, Issue:4

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Colon; Dinucleoside Phosphates; Guinea Pigs; Male; Rats; Rats, Wistar; Suramin; Uridine Triphosphate

1998
Physiological evidence for a P2Y receptor responsive to diadenosine polyphosphates in human lung via Ca(2+) release studies in bronchial epithelial cells.
    Biochemical pharmacology, 2001, Mar-01, Volume: 61, Issue:5

    Topics: Adenosine Triphosphate; Animals; Biological Transport; Bronchi; Calcium; Cells, Cultured; Chromatography, High Pressure Liquid; Dinucleoside Phosphates; Epithelial Cells; Humans; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Agonists; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Uridine Triphosphate

2001
Activity of diadenosine polyphosphates at P2Y receptors stably expressed in 1321N1 cells.
    European journal of pharmacology, 2001, Nov-02, Volume: 430, Issue:2-3

    Topics: Adenosine Diphosphate; Calcium; Carbachol; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Gene Expression; Humans; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Tumor Cells, Cultured; Uridine Triphosphate

2001
UTP and diadenosine tetraphosphate accelerate wound healing in the rabbit cornea.
    Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 2004, Volume: 24, Issue:3

    Topics: Animals; Cornea; Corneal Injuries; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Epithelium; Male; Mitogen-Activated Protein Kinases; Nucleotides; Phosphorylation; Platelet Aggregation Inhibitors; Purinergic P2 Receptor Antagonists; Rabbits; Signal Transduction; Uridine Triphosphate; Wound Healing

2004
The promiscuous ectonucleotidase NPP1: molecular insights into substrate binding and hydrolysis.
    Biochimica et biophysica acta. General subjects, 2017, Volume: 1861, Issue:3

    Topics: Adenosine Triphosphate; Amino Acids; Binding Sites; Cyclic AMP; Cyclic GMP; Dinucleoside Phosphates; Humans; Hydrolysis; Phosphoric Diester Hydrolases; Protein Binding; Pyrophosphatases; Substrate Specificity; Thymidine Monophosphate; Uridine Triphosphate

2017
ATP, an agonist at the rat P2Y(4) receptor, is an antagonist at the human P2Y(4) receptor.
    Molecular pharmacology, 2000, Volume: 57, Issue:5

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Dinucleoside Phosphates; Humans; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Receptors, Purinergic P2; Species Specificity; Tumor Cells, Cultured; Uridine Diphosphate

2000