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diadenosine tetraphosphate and p(1),p(5)-di(adenosine-5'-)pentaphosphate

diadenosine tetraphosphate has been researched along with p(1),p(5)-di(adenosine-5'-)pentaphosphate in 77 studies

Research

Studies (77)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (7.79)	18.7374
1990's	41 (53.25)	18.2507
2000's	17 (22.08)	29.6817
2010's	13 (16.88)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Kisteneff, E; Kolodny, NH; Rapaport, E; Redfield, C	1
Díaz-Rey, MA; Miras-Portugal, MT; Pintor, J; Torres, M	1
Miras-Portugal, MT; Pintor, J; Torres, M	1
Günther Sillero, MA; Sillero, A; Wasternack, C	1
Bertics, PJ; Leventhal, PS	1
Hoyle, CH	1
Castro, E; Gonzalez, MP; Miras-Portugal, MT; Torres, M	1
Paton, DM; Stone, TW	1
Delicado, EG; Miras-Portugal, MT; Rodriguez del Castillo, A; Torres, M	1
Bone, R; Cheng, YC; Wolfenden, R	1
Amrute, SB; Modak, MJ; Pandey, VN; Satav, JG	1
Chottard, G; Chottard, JC; Girault, JP; le Pecq, B; Muzard, G; Segal, E	1
Ankorina, I; Haxelmans, S; Kleta, R; Schlatter, E	1
Ogilvie, A; Schulze-Lohoff, E; Sterzel, RB; Zanner, S	1
Miras-Portugal, MT; Pintor, J	2
Miras-Portugal, MT; Mora, F; Pintor, J; Porras, A	2
Klishin, A; Krishtal, O; Lozovaya, N; Miras-Portugal, MT; Pintor, J	1
Dimmick, MA; Hilderman, RH; Jones, GB; Lilien, JE; Tate, DH; Zimmerman, JK	1
Chen, H; McLennan, AG	1
Alekseev, AE; Jovanovic, A; Terzic, A; Zhang, S	1
Culic, O; Lemmens, R; Teuchy, H; Vanduffel, L	1
Burnstock, G; Hoyle, CH; Postorino, A	1
Geiger, JD; Holden, CP; Padua, RA	1
Borucki, U; Enck, G; Hohage, H; Reinhardt, C; Schlatter, E; Schlüter, H; Zidek, W	1
Assmann, G; Beinlich, A; Heidenreich, S; Nofer, JR; Schlüter, H; Tepel, M; Walter, M; Zidek, W	1
Edwards, SW; Gasmi, L; McLennan, AG	1
Bläsius, R; Ogilvie, A; Schulze-Lohoff, E; Sterzel, RB	1
Bowes, J; Kennedy, C; McIntyre, CA; Obeid, S; Sneddon, P; Westfall, TD	1
Gomez De Aranda, I; Marti, E; Mateo, J; Miras-Portugal, MT; Rotllan, P; Solsona, C	1
Mezzasoma, I; Minelli, A; Moroni, M	1
Alekseev, AE; Jovanovic, A; Terzic, A	1
Mateo, J; Miras-Portugal, MT; Rotllán, P	1
Fideu, MD; García-Carmona, F; Gualix, J; Miras-Portugal, MT; Pintor, J; Rotllán, P	1
Jankowski, J; Schlüter, H; Spieker, C; Tepel, M; Zidek, W	1
Kanaide, H; Kawasaki, J; Kobayashi, S; Nishimura, J; Sumiyoshi, R; Takahashi, S	1
Bachmann, J; Jankowski, J; Ruess, C; Schlüter, H; Tepel, M; Terliesner, J; van der Giet, M; Zidek, W	1
Asensio, AC; Oaknin, S; Rodríguez-Ferrer, CR; Rotllán, P	1
Hohage, H; Hollah, P; Khattab, M; Rahn, KH; Schlatter, E	1
Hohage, H; Rahn, KH; Schlatter, E; Stachon, A; Stegemann, H	1
Bailey, SJ; Hourani, SM; Johnson, CR; Tennant, JP	1
Battastini, AM; Bonan, CD; Emanuelli, T; Sarkis, JJ	1
Brown, SG; Burnstock, G; King, BF; Wildman, SS	1
Jankowski, J; Potthoff, W; Schlüter, H; Tepel, M; van der Giet, M; Zidek, W	1
Flores, NA; Sheridan, DJ; Stavrou, BM	1
Edgecombe, M; Fisher, MJ; McLennan, AG	1
Breittmayer, JP; Frelin, C; Vigne, P	1
Castagnola, M; Floris, G; Medda, R; Messana, I; Padiglia, A	1
Barenbrock, M; Hausberg, M; Hollah, P; Kosch, M; Letzel, M; Rahn, KH; Schlatter, E	1
Blackburn, GM; Cohen, T; Flores, NA; Lawrence, C; Sheridan, DJ; Stavrou, BM	1
Beck, C; Flores, NA; Stavrou, BM	1
Barnes, A; Boughtflower, R; Camacho, J; Cousens, D; Marshall, F; Patel, K; Paterson, C	1
Alonso, MC; Bautista, A; Carracedo, G; Peral, A; Pintor, J	1
Bianchi, BR; Briggs, CA; Burgard, EC; Cartmell, J; Chu, KL; Faltynek, C; Jarvis, MF; Lynch, KJ; McDonald, HA; McKenna, DG	1
Janssen, AK; Pelster, F; Rahn, KH; Schlatter, E; Steinmetz, M	1
Haghiac, M; Hilderman, RH; Pojoga, LH	1
Henning, L; Jankowski, J; Jankowski, V; Laufer, U; Schlüter, H; Tepel, M; van der Giet, M; Zidek, W	1
Güngär, N; Jankowski, J; Jankowski, V; Luo, J; Neumann, J; Schlüter, H; Schmitz, W; Zidek, W	1
Gasull, X; Gual, A; Peral, A; Pintor, J; Soto, D	1
Acharya, KR; Baker, MD; Holloway, DE; Swaminathan, GJ	1
Acosta, MC; Carracedo, G; Gallar, J; Peral, A; Pintor, J	1
Mediero, A; Peral, A; Pintor, J	1
Günthner, T; Jalkanen, S; Jankowski, J; Jankowski, V; Yegutkin, GG; Zidek, W	1
Carracedo, G; Peral, A; Pintor, J	2
Chen, FY; Chu, HM; Ko, TP; Wang, AH	1
Castany, M; Catala, J; Gasull, X; Gual, A; Jordi, I; Morales, M; Pintor, J	1
Carracedo, G; González-Méijome, JM; Pintor, J	1
Carracedo, G; Guzman-Aranguez, A; Loma, P; Pintor, J	1
Cacho, I; Carracedo, G; Pintor, J; Sanchez-Naves, J	1
Jankowski, J; Jankowski, V; Schulz, A; Zidek, W	1
Anashkin, VA; Baykov, AA; Lahti, R; Orlov, VN; Salminen, A; Tuominen, HK	1
Abramochkin, DV; Kuzmin, VS; Pustovit, KB	1
Carballo, J; Carracedo, G; González-Méijome, JM; Martín-Gil, A; Pintor, J	1
Kimura, Y; Sasaki, K; Sasaki, M; Tanaka, C	1
Kimura, Y; Oka, M; Tanaka, C	1

Reviews

4 review(s) available for diadenosine tetraphosphate and p(1),p(5)-di(adenosine-5'-)pentaphosphate

Article	Year
P2 purinergic receptors for diadenosine polyphosphates in the nervous system. General pharmacology, 1995, Volume: 26, Issue:2 Topics: Animals; Dinucleoside Phosphates; Male; Nervous System; Receptors, Purinergic P2	1995
Adenine dinucleotides: a novel class of signalling molecules. Journal of autonomic pharmacology, 1996, Volume: 16, Issue:6 Topics: Animals; Cell Division; Dinucleoside Phosphates; DNA; Humans; Muscle, Smooth, Vascular; Platelet Activation; Rats; Signal Transduction	1996
Intracellular diadenosine polyphosphates: a novel family of inhibitory ligands of the ATP-sensitive K+ channel. Biochemical pharmacology, 1997, Jul-15, Volume: 54, Issue:2 Topics: Adenosine Triphosphate; Animals; Cell Membrane; Dinucleoside Phosphates; Ion Channel Gating; Islets of Langerhans; Ligands; Myocardium; Polyphosphates; Potassium Channel Blockers; Potassium Channels	1997
The effects of diadenosine polyphosphates on the cardiovascular system. Cardiovascular research, 1999, Volume: 42, Issue:1 Topics: Action Potentials; Animals; Cardiovascular System; Dinucleoside Phosphates; Endothelium, Vascular; Humans; Myocardial Ischemia; Platelet Aggregation Inhibitors; Potassium Channels; Receptors, Purinergic; Second Messenger Systems; Vascular Resistance; Vasodilation	1999

Trials

1 trial(s) available for diadenosine tetraphosphate and p(1),p(5)-di(adenosine-5'-)pentaphosphate

Article	Year
The influence of rigid gas permeable lens wear on the concentrations of dinucleotides in tears and the effect on dry eye signs and symptoms in keratoconus. Contact lens & anterior eye : the journal of the British Contact Lens Association, 2016, Volume: 39, Issue:5 Topics: Adult; Biomarkers; Contact Lenses; Dinucleoside Phosphates; Dry Eye Syndromes; Female; Gases; Humans; Keratoconus; Male; Middle Aged; Permeability; Reproducibility of Results; Sensitivity and Specificity; Symptom Assessment; Tears; Young Adult	2016

Article

Year

The influence of rigid gas permeable lens wear on the concentrations of dinucleotides in tears and the effect on dry eye signs and symptoms in keratoconus.

Contact lens & anterior eye : the journal of the British Contact Lens Association, 2016, Volume: 39, Issue:5

Topics: Adult; Biomarkers; Contact Lenses; Dinucleoside Phosphates; Dry Eye Syndromes; Female; Gases; Humans; Keratoconus; Male; Middle Aged; Permeability; Reproducibility of Results; Sensitivity and Specificity; Symptom Assessment; Tears; Young Adult

2016

Other Studies

72 other study(ies) available for diadenosine tetraphosphate and p(1),p(5)-di(adenosine-5'-)pentaphosphate

Article	Year
Ap4A and Ap5A prefer folded unstacked conformations at pH 4-5, in sharp contrast with Ap2A and Ap3A. FEBS letters, 1979, Nov-01, Volume: 107, Issue:1 Topics: Adenine Nucleotides; Adenosine Monophosphate; Dinucleoside Phosphates; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Molecular; Nucleic Acid Conformation	1979
Presence of diadenosine polyphosphates--Ap4A and Ap5A--in rat brain synaptic terminals. Ca2+ dependent release evoked by 4-aminopyridine and veratridine. Neuroscience letters, 1992, Mar-02, Volume: 136, Issue:2 Topics: 4-Aminopyridine; Animals; Brain Chemistry; Calcium; Chromatography, High Pressure Liquid; Dinucleoside Phosphates; Exocytosis; In Vitro Techniques; Male; Nerve Endings; Rats; Rats, Inbred Strains; Synapses; Veratridine	1992
Carbachol induced release of diadenosine polyphosphates--Ap4A and Ap5A--from perfused bovine adrenal medulla and isolated chromaffin cells. Life sciences, 1991, Volume: 48, Issue:24 Topics: Adenosine Triphosphate; Adrenal Medulla; Animals; Carbachol; Catecholamines; Cattle; Chromaffin Granules; Chromatography, High Pressure Liquid; Dinucleoside Phosphates; Phosphoric Diester Hydrolases	1991
Diadenosine polyphosphates inhibit the action of ribonucleotide reductase on ADP. Biochemistry international, 1991, Volume: 23, Issue:1 Topics: Adenosine Diphosphate; Cell Membrane Permeability; Chromatography, Gel; Chromatography, High Pressure Liquid; Dinucleoside Phosphates; Enzyme Inhibitors; Oxidation-Reduction; Ribonucleotide Reductases; Yeasts	1991
Kinetic analysis of protein kinase C: product and dead-end inhibition studies using ADP, poly(L-lysine), nonhydrolyzable ATP analogues, and diadenosine oligophosphates. Biochemistry, 1991, Feb-05, Volume: 30, Issue:5 Topics: Adenosine Diphosphate; Adenylyl Imidodiphosphate; Animals; Brain; Dinucleoside Phosphates; In Vitro Techniques; Kinetics; Polylysine; Protein Kinase C; Rats	1991
Pharmacological activity of adenine dinucleotides in the periphery: possible receptor classes and transmitter function. General pharmacology, 1990, Volume: 21, Issue:6 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adrenal Medulla; Animals; Blood Platelets; Chromaffin Granules; Dinucleoside Phosphates; Humans; NAD; NADP; Receptors, Purinergic	1990
Effect of diadenosine polyphosphates on catecholamine secretion from isolated chromaffin cells. British journal of pharmacology, 1990, Volume: 100, Issue:2 Topics: Adrenal Glands; Animals; Catecholamines; Cattle; Chromaffin System; Dinucleoside Phosphates; In Vitro Techniques; Nicotine; Perfusion; Potassium	1990
Possible subtypes of ATP receptor producing contraction of rat vas deferens, revealed by cross-desensitisation. General pharmacology, 1989, Volume: 20, Issue:1 Topics: Adenosine Triphosphate; Animals; Dinucleoside Phosphates; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Rats; Receptors, Purinergic; Vas Deferens	1989
Subcellular distribution studies of diadenosine polyphosphates--Ap4A and Ap5A--in bovine adrenal medulla: presence in chromaffin granules. Journal of neurochemistry, 1988, Volume: 51, Issue:6 Topics: Adenosine Diphosphate; Adenosine Kinase; Adenosine Monophosphate; Adenosine Triphosphate; Adenylate Kinase; Adrenal Medulla; Animals; Cattle; Chromaffin Granules; Chromaffin System; Chromatography, High Pressure Liquid; Cytosol; Dinucleoside Phosphates; Phosphoric Monoester Hydrolases	1988
Inhibition of adenosine and thymidylate kinases by bisubstrate analogs. The Journal of biological chemistry, 1986, Dec-15, Volume: 261, Issue:35 Topics: Adenine Nucleotides; Adenosine Kinase; Dinucleoside Phosphates; Humans; Kinetics; Leukemia, Myeloid, Acute; Liver; Nucleoside-Phosphate Kinase; Phosphotransferases; Protein Binding; Structure-Activity Relationship	1986
Inhibition of terminal deoxynucleotidyl transferase by adenine dinucleotides. Unique inhibitory action of Ap5A. FEBS letters, 1987, Mar-09, Volume: 213, Issue:1 Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Cattle; Dinucleoside Phosphates; DNA Nucleotidylexotransferase; DNA Nucleotidyltransferases; Dose-Response Relationship, Drug; Kinetics; Thymine Nucleotides	1987
Structure determination of the adduct formed between the signal nucleotide diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) and cis-[Pt(NH3)2Cl2]. Biopolymers, 1984, Volume: 23, Issue:9 Topics: Adenine Nucleotides; Chemical Phenomena; Chemistry; Cisplatin; Dinucleoside Phosphates; Magnetic Resonance Spectroscopy	1984
Effects of diadenosine polyphosphates, ATP and angiotensin II on cytosolic Ca2+ activity and contraction of rat mesangial cells. Pflugers Archiv : European journal of physiology, 1995, Volume: 430, Issue:5 Topics: Adenosine Triphosphate; Angiotensin II; Animals; Calcium; Cell Line; Cytosol; Dinucleoside Phosphates; Fura-2; Glomerular Mesangium; Hypertension; Muscle Contraction; Patch-Clamp Techniques; Rats; Rats, Inbred SHR; Rats, Inbred WKY	1995
Vasoactive diadenosine polyphosphates promote growth of cultured renal mesangial cells. Hypertension (Dallas, Tex. : 1979), 1995, Volume: 26, Issue:6 Pt 1 Topics: Analysis of Variance; Animals; Blotting, Northern; Cells, Cultured; Dinucleoside Phosphates; DNA; Epidermal Growth Factor; Glomerular Mesangium; Male; Mitosis; Platelet-Derived Growth Factor; Rats; Rats, Sprague-Dawley; Second Messenger Systems; Serotonin	1995
A novel receptor for diadenosine polyphosphates coupled to calcium increase in rat midbrain synaptosomes. British journal of pharmacology, 1995, Volume: 115, Issue:6 Topics: Adenosine Triphosphate; Animals; Calcium; Dinucleoside Phosphates; Male; Mesencephalon; Presynaptic Terminals; Rats; Rats, Wistar; Second Messenger Systems; Suramin; Synaptosomes; Tetrodotoxin; Time Factors	1995
Dopamine receptor blockade inhibits the amphetamine-induced release of diadenosine polyphosphates, diadenosine tetraphosphate and diadenosine pentaphosphate, from neostriatum of the conscious rat. Journal of neurochemistry, 1995, Volume: 64, Issue:2 Topics: Adenosine; Adenosine Monophosphate; Amphetamine; Animals; Corpus Striatum; Dinucleoside Phosphates; Dopamine Antagonists; Haloperidol; Male; Perfusion; Rats; Rats, Wistar	1995
Possible functional role of diadenosine polyphosphates: negative feedback for excitation in hippocampus. Neuroscience, 1994, Volume: 58, Issue:2 Topics: Animals; Dinucleoside Phosphates; Feedback; Hippocampus; In Vitro Techniques; Membrane Potentials; Rats; Rats, Wistar; Receptors, Purinergic P1; Synapses; Synaptic Transmission; Theophylline	1994
Adenylated dinucleotide binding to the adenosine 5',5'''-P1,P4-tetraphosphate mouse heart receptor. Biochemical and biophysical research communications, 1994, Apr-29, Volume: 200, Issue:2 Topics: Animals; Antibodies, Monoclonal; Cell Membrane; Dinucleoside Phosphates; Female; In Vitro Techniques; Kinetics; Mice; Models, Molecular; Myocardium; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Thermodynamics	1994
The bis(adenosin-N6-yl)alkanes, a family of potential dinucleoside-polyphosphate analogue precursors. Cytotoxicity, adenosine-receptor binding and metabolism. European journal of biochemistry, 1993, Jun-15, Volume: 214, Issue:3 Topics: Adenosine; Adenosine Deaminase; Alkanes; Animals; Biological Transport; Cell Division; Cells, Cultured; Cyclic AMP; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Humans; Receptors, Purinergic; Serum Albumin	1993
Amphetamine-induced release of diadenosine polyphosphates--Ap4A and Ap5A--from caudate putamen of conscious rat. Neuroscience letters, 1993, Feb-05, Volume: 150, Issue:1 Topics: Adenine Nucleotides; Amphetamine; Animals; Caudate Nucleus; Chromatography, High Pressure Liquid; Dinucleoside Phosphates; Injections, Intraperitoneal; Male; Putamen; Rats; Rats, Wistar	1993
Diadenosine polyphosphate-induced inhibition of cardiac KATP channels: operative state-dependent regulation by a nucleoside diphosphate. Pflugers Archiv : European journal of physiology, 1996, Volume: 431, Issue:5 Topics: Animals; Dinucleoside Phosphates; Guinea Pigs; Ion Channel Gating; Myocardium; Potassium Channel Blockers; Potassium Channels; Second Messenger Systems; Uridine Diphosphate; Vasoconstrictor Agents	1996
Regulation of proliferation of LLC-MK2 cells by nucleosides and nucleotides: the role of ecto-enzymes. The Biochemical journal, 1996, Jun-01, Volume: 316 ( Pt 2) Topics: 5'-Nucleotidase; Acid Anhydride Hydrolases; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Alkaline Phosphatase; Animals; Cell Division; Cell Line; Cell Line, Transformed; Dinucleoside Phosphates; Dipyridamole; Enzyme Inhibitors; HeLa Cells; Humans; Levamisole; Nucleoside-Triphosphatase; Nucleosides; Nucleotides; Suramin; Thymidine; Triazines	1996
Pre- and postjunctional effects of diadenosine polyphosphates in the guinea-pig vas deferens. The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:11 Topics: Animals; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Receptors, Purinergic; Vas Deferens	1995
Regulation of ryanodine receptor calcium release channels by diadenosine polyphosphates. Journal of neurochemistry, 1996, Volume: 67, Issue:2 Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channels; Cerebral Cortex; Dinucleoside Phosphates; Ion Channel Gating; Kinetics; Male; Muscle Proteins; Muscle, Skeletal; Myocardium; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Ryanodine; Ryanodine Receptor Calcium Release Channel; Structure-Activity Relationship	1996
Effects of diadenosine polyphosphates on renal function and blood pressure in anesthetized Wistar rats. Journal of the American Society of Nephrology : JASN, 1996, Volume: 7, Issue:8 Topics: Anesthesia; Animals; Blood Pressure; Bosentan; Cyclooxygenase Inhibitors; Dinucleoside Phosphates; Diuresis; Endothelins; Enzyme Inhibitors; Glomerular Filtration Rate; Indomethacin; Kidney; Male; Natriuresis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Prostaglandins; Rats; Rats, Wistar; Sulfonamides; Vasoconstrictor Agents	1996
Diadenosine polyphosphates induce transplasma membrane calcium influx in cultured glomerular mesangial cells. European journal of clinical investigation, 1996, Volume: 26, Issue:12 Topics: Adenosine Triphosphate; Affinity Labels; Angiotensin II; Animals; Calcium; Cell Membrane; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Glomerular Mesangium; Male; Phospholipase D; Rats; Rats, Inbred WKY; Second Messenger Systems; Suramin; Type C Phospholipases; Vasoconstrictor Agents	1996
Diadenosine polyphosphates induce intracellular Ca2+ mobilization in human neutrophils via a pertussis toxin sensitive G-protein. Immunology, 1997, Volume: 90, Issue:1 Topics: Adenosine Triphosphate; Calcium; Cell Culture Techniques; Dinucleoside Phosphates; GTP-Binding Proteins; Humans; Neutrophils; Pertussis Toxin; Receptors, Purinergic P2; Virulence Factors, Bordetella	1997
The interaction of diadenosine polyphosphates with P2x-receptors in the guinea-pig isolated vas deferens. British journal of pharmacology, 1997, Volume: 121, Issue:1 Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Analysis of Variance; Animals; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Lethal Dose 50; Male; Muscle Contraction; Norepinephrine; Platelet Aggregation Inhibitors; Pyridoxal Phosphate; Receptors, Purinergic P2; Second Messenger Systems; Suramin; Vas Deferens; Vasoconstrictor Agents	1997
Diadenosine polyphosphate hydrolase from presynaptic plasma membranes of Torpedo electric organ. The Biochemical journal, 1997, May-01, Volume: 323 ( Pt 3) Topics: Acid Anhydride Hydrolases; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cations, Divalent; Diethyl Pyrocarbonate; Dinucleoside Phosphates; Electric Organ; Enzyme Inhibitors; Hydrogen-Ion Concentration; Kinetics; Nerve Tissue Proteins; Presynaptic Terminals; Pyridoxal Phosphate; Torpedo	1997
Human seminal plasma soluble 5'-nucleotidase: regulatory aspects of the dephosphorylation of nucleoside 5'-monophosphates. Biochemical and molecular medicine, 1997, Volume: 61, Issue:1 Topics: 5'-Nucleotidase; Adenosine Monophosphate; Cytidine Monophosphate; Dinucleoside Phosphates; Energy Metabolism; Guanosine Monophosphate; Humans; Inosine Monophosphate; Male; Phosphorylation; Purine Nucleotides; Semen; Solubility; Uridine Monophosphate; Vanadates	1997
Ecto-enzymatic hydrolysis of diadenosine polyphosphates by cultured adrenomedullary vascular endothelial cells. The American journal of physiology, 1997, Volume: 273, Issue:3 Pt 1 Topics: Adrenal Medulla; Animals; Cattle; Cell Membrane; Cells, Cultured; Dextrans; Dinucleoside Phosphates; Endothelium, Vascular; Exocytosis; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Microspheres; Models, Biological	1997
Characterization of diadenosine polyphosphate transport into chromaffin granules from adrenal medulla. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1997, Volume: 11, Issue:12 Topics: Adrenal Medulla; Animals; Atractyloside; Biological Transport; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Carrier Proteins; Cattle; Chromaffin Granules; Dinucleoside Phosphates; Ethylmaleimide; Kinetics; Models, Biological; Models, Chemical; Nigericin; Substrate Specificity; Suramin; Tritium; Valinomycin	1997
Effect of diadenosine polyphosphates on Ca2+ ATPase activity. Journal of molecular medicine (Berlin, Germany), 1997, Volume: 75, Issue:9 Topics: Adenosine Triphosphate; Calcium-Transporting ATPases; Dinucleoside Phosphates; Humans; Structure-Activity Relationship	1997
Diadenosine polyphosphates directly relax porcine coronary arterial smooth muscle. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 283, Issue:2 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Caffeine; Calcium; Coronary Vessels; Cyclic AMP; Cyclic GMP; Dinucleoside Phosphates; Histamine; In Vitro Techniques; Muscle, Smooth, Vascular; Potassium Channel Blockers; Swine; Vasodilation	1997
Diadenosine polyphosphates' action on calcium and vessel contraction. American journal of hypertension, 1997, Volume: 10, Issue:12 Pt 1 Topics: Animals; Calcium; Dinucleoside Phosphates; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred WKY; Vasoconstriction	1997
Potent inhibition of specific diadenosine polyphosphate hydrolases by suramin. FEBS letters, 1998, Jun-12, Volume: 429, Issue:2 Topics: Acid Anhydride Hydrolases; Animals; Brain; Dinucleoside Phosphates; Enzyme Inhibitors; Hydrolysis; Male; Neoplasm Proteins; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Rats; Rats, Wistar; Suramin; Tissue Extracts	1998
Effects of diadenosine polyphosphates on systemic and regional hemodynamics in anesthetized rats. Kidney & blood pressure research, 1998, Volume: 21, Issue:1 Topics: Animals; Blood Pressure; Cardiac Output; Dinucleoside Phosphates; Femoral Artery; Hemodynamics; Kidney; Male; Nitroprusside; Norepinephrine; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Regional Blood Flow; Second Messenger Systems; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents	1998
Effects of diadenosine polyphosphates on the intracellular Ca2+ concentration in endothelial cells. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 1998, Volume: 8, Issue:4 Topics: Adenosine Triphosphate; Angiotensin II; Animals; Arginine Vasopressin; Calcium; Cell Line; Cells, Cultured; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Endothelium, Vascular; Fluorescent Antibody Technique; Humans; Rats; Rats, Inbred WKY	1998
Effects of adenosine 5'-triphosphate, uridine 5'-triphosphate, adenosine 5'-tetraphosphate and diadenosine polyphosphates in guinea-pig taenia caeci and rat colon muscularis mucosae. Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 358, Issue:4 Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Colon; Dinucleoside Phosphates; Guinea Pigs; Male; Rats; Rats, Wistar; Suramin; Uridine Triphosphate	1998
Catabolism of Ap4A and Ap5A by rat brain synaptosomes. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1998, Volume: 31, Issue:12 Topics: Animals; Cerebral Cortex; Dinucleoside Phosphates; Male; Rats; Rats, Wistar; Second Messenger Systems; Synaptosomes	1998
Selectivity of diadenosine polyphosphates for rat P2X receptor subunits. European journal of pharmacology, 1999, Feb-12, Volume: 367, Issue:1 Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Binding, Competitive; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Membrane Potentials; Oocytes; Purinergic P2 Receptor Agonists; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2X3; Receptors, Purinergic P2X4; RNA, Messenger; Xenopus	1999
High-performance liquid chromatographic assay of the diadenosine polyphosphates in human platelets. Analytical biochemistry, 1999, Apr-10, Volume: 269, Issue:1 Topics: Blood Platelets; Chromatography, High Pressure Liquid; Dinucleoside Phosphates; Humans	1999
Diadenosine polyphosphates and the control of cyclic AMP concentrations in isolated rat liver cells. FEBS letters, 1999, Sep-03, Volume: 457, Issue:3 Topics: Adenosine Triphosphate; Animals; Cyclic AMP; Dinucleoside Phosphates; Glucagon; In Vitro Techniques; Liver; Male; Rats; Rats, Wistar; Receptors, Purinergic P2; Signal Transduction; Thionucleotides	1999
Diadenosine polyphosphates as antagonists of the endogenous P2Y(1) receptor in rat brain capillary endothelial cells of the B7 and B10 clones. British journal of pharmacology, 2000, Volume: 129, Issue:7 Topics: Adenosine Diphosphate; Adenylyl Cyclases; Animals; Brain; Calcium; Cells, Cultured; Clone Cells; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Endothelium, Vascular; Purinergic P2 Receptor Antagonists; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y1	2000
Separation of diadenosine polyphosphates by capillary electrophoresis. Electrophoresis, 2000, Volume: 21, Issue:12 Topics: Borates; Buffers; Carbonates; Dinucleoside Phosphates; Electrophoresis, Capillary	2000
A novel assay for determination of diadenosine polyphosphates in human platelets: studies in normotensive subjects and in patients with essential hypertension. Journal of hypertension, 2001, Volume: 19, Issue:2 Topics: Adult; Blood Platelets; Dinucleoside Phosphates; Female; Humans; Hypertension; Male; Reproducibility of Results	2001
Coronary vasomotor and cardiac electrophysiologic effects of diadenosine polyphosphates and nonhydrolyzable analogs in the guinea pig. Journal of cardiovascular pharmacology, 2001, Volume: 37, Issue:5 Topics: Action Potentials; Animals; Coronary Vessels; Dinucleoside Phosphates; Guinea Pigs; Heart; Heart Rate; Hydrolysis; Male; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P1; Receptors, Purinergic P2; Structure-Activity Relationship; Vasoconstrictor Agents; Vasomotor System	2001
Changes in extracellular pH and myocardial ischaemia alter the cardiac effects of diadenosine tetraphosphate and pentaphosphate. British journal of pharmacology, 2001, Volume: 134, Issue:3 Topics: Action Potentials; Animals; Dinucleoside Phosphates; Extracellular Space; Guinea Pigs; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion; Platelet Aggregation Inhibitors; Vasoconstrictor Agents	2001
Activity of diadenosine polyphosphates at P2Y receptors stably expressed in 1321N1 cells. European journal of pharmacology, 2001, Nov-02, Volume: 430, Issue:2-3 Topics: Adenosine Diphosphate; Calcium; Carbachol; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Gene Expression; Humans; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Tumor Cells, Cultured; Uridine Triphosphate	2001
Presence of diadenosine polyphosphates in human tears. Pflugers Archiv : European journal of physiology, 2002, Volume: 443, Issue:3 Topics: Animals; Chromatography, High Pressure Liquid; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Epithelium, Corneal; Humans; Rabbits; Tears	2002
Potent desensitization of human P2X3 receptors by diadenosine polyphosphates. European journal of pharmacology, 2002, Jan-25, Volume: 435, Issue:2-3 Topics: Adenosine Triphosphate; Animals; Carbachol; Cholinergic Agonists; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Electrophysiology; Humans; Oocytes; Receptors, Purinergic P2; Receptors, Purinergic P2X3; Recombinant Proteins; Xenopus laevis	2002
Vasoactivity of diadenosine polyphosphates in human small mesenteric resistance arteries. The Journal of pharmacology and experimental therapeutics, 2002, Volume: 302, Issue:2 Topics: Animals; Dinucleoside Phosphates; Humans; In Vitro Techniques; Kinetics; Mesenteric Arteries; Muscle Contraction; Rats; Vascular Resistance	2002
Inhibition by adenine dinucleotides of ATP-induced prostacyclin release by bovine aortic endothelial cells. Biochemical pharmacology, 2002, Aug-01, Volume: 64, Issue:3 Topics: Adenosine Triphosphate; Animals; Aorta; Calcium; Cattle; Dinucleoside Phosphates; Endothelium, Vascular; Epoprostenol	2002
Identification and quantification of diadenosine polyphosphate concentrations in human plasma. Arteriosclerosis, thrombosis, and vascular biology, 2003, Jul-01, Volume: 23, Issue:7 Topics: Chromatography, High Pressure Liquid; Dinucleoside Phosphates; Female; Humans; Male; Middle Aged; Polyphosphates; Probability; Reproducibility of Results; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2003
Endogenous diadenosine tetraphosphate, diadenosine pentaphosphate, and diadenosine hexaphosphate in human myocardial tissue. Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:5 Topics: Cholinergic Agents; Chromatography, Affinity; Chromatography, Gel; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cytoplasmic Granules; Dinucleoside Phosphates; Heart; Humans; Myocardium; Potassium Channels; Receptors, Purinergic P2; Receptors, Purinergic P2X; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry, Ultraviolet; Vasoconstriction	2004
Effects of dinucleoside polyphosphates on trabecular meshwork cells and aqueous humor outflow facility. The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:3 Topics: Animals; Aqueous Humor; Calcium; Cattle; Cells, Cultured; Dinucleoside Phosphates; Intraocular Pressure; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Trabecular Meshwork	2005
Crystal structures of eosinophil-derived neurotoxin (EDN) in complex with the inhibitors 5'-ATP, Ap3A, Ap4A, and Ap5A. Biochemistry, 2006, Jan-17, Volume: 45, Issue:2 Topics: Adenosine Triphosphate; Adenylate Kinase; Binding Sites; Crystallography, X-Ray; Dinucleoside Phosphates; Eosinophil-Derived Neurotoxin; Humans; Protein Structure, Tertiary	2006
Increased levels of diadenosine polyphosphates in dry eye. Investigative ophthalmology & visual science, 2006, Volume: 47, Issue:9 Topics: Adult; Chromatography, High Pressure Liquid; Dinucleoside Phosphates; Dry Eye Syndromes; Female; Humans; Male; Tears	2006
Dual roles of diadenosine polyphosphates in corneal epithelial cell migration. Investigative ophthalmology & visual science, 2006, Volume: 47, Issue:10 Topics: Animals; Cell Movement; Cells, Cultured; Chromatography, High Pressure Liquid; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Epithelium, Corneal; Fluorescent Antibody Technique, Indirect; Keratins; Microscopy, Confocal; Nucleotides; Purinergic P2 Receptor Antagonists; Rabbits; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Wound Healing	2006
Dinucleotide polyphosphates contribute to purinergic signalling via inhibition of adenylate kinase activity. Bioscience reports, 2008, Volume: 28, Issue:4 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylate Kinase; Cells, Cultured; Dinucleoside Phosphates; Humans; Nucleotides; Signal Transduction; Suramin	2008
Diadenosine polyphosphates in tears of Sjogren syndrome patients. Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:11 Topics: Adult; Aged; Chromatography, High Pressure Liquid; Dinucleoside Phosphates; Female; Humans; Male; Middle Aged; Sjogren's Syndrome; Surveys and Questionnaires; Tears	2010
Binding and catalysis of Humulus lupulus adenylate isopentenyltransferase for the synthesis of isopentenylated diadenosine polyphosphates. FEBS letters, 2010, Sep-24, Volume: 584, Issue:18 Topics: Alkyl and Aryl Transferases; Catalysis; Dinucleoside Phosphates; Humulus; Mutation; Protein Conformation	2010
Glaucoma patients present increased levels of diadenosine tetraphosphate, Ap(4)A, in the aqueous humour. Experimental eye research, 2011, Volume: 92, Issue:3 Topics: Age Distribution; Aged; Aged, 80 and over; Aqueous Humor; Cataract Extraction; Chromatography, High Pressure Liquid; Dinucleoside Phosphates; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Sex Distribution	2011
Changes in diadenosine polyphosphates during alignment-fit and orthokeratology rigid gas permeable lens wear. Investigative ophthalmology & visual science, 2012, Jul-03, Volume: 53, Issue:8 Topics: Adult; Chromatography, High Pressure Liquid; Contact Lenses; Cornea; Dinucleoside Phosphates; Female; Fluorophotometry; Humans; Male; Orthokeratologic Procedures; Platelet Aggregation Inhibitors; Prosthesis Fitting; Tears; Vasoconstrictor Agents; Young Adult	2012
Diadenosine polyphosphates release by human corneal epithelium. Experimental eye research, 2013, Volume: 113 Topics: Adult; Blinking; Cell Line; Chromatography, High Pressure Liquid; Dinucleoside Phosphates; Epithelium, Corneal; Female; Humans; L-Lactate Dehydrogenase; Male; Stress, Mechanical; Tears; Young Adult	2013
Diadenosine polyphosphates after laser in situ keratomileusis and photorefractive keratectomy refractive techniques. Acta ophthalmologica, 2014, Volume: 92, Issue:1 Topics: Adult; Chromatography, High Pressure Liquid; Dinucleoside Phosphates; Dry Eye Syndromes; Eye Proteins; Female; Humans; Keratomileusis, Laser In Situ; Male; Middle Aged; Myopia; Photorefractive Keratectomy; Surveys and Questionnaires; Tears; Wound Healing; Young Adult	2014
Highly sensitive, selective and rapid LC-MS method for simultaneous quantification of diadenosine polyphosphates in human plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2014, Jun-15, Volume: 961 Topics: Chromatography, High Pressure Liquid; Dinucleoside Phosphates; Humans; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization	2014
Diadenosine polyphosphates in the tears of aniridia patients. Acta ophthalmologica, 2015, Volume: 93, Issue:5 Topics: Adolescent; Adult; Aging; Aniridia; Child; Chromatography, High Pressure Liquid; Dinucleoside Phosphates; Female; Humans; Male; Middle Aged; Surveys and Questionnaires; Tears; Young Adult	2015
Cystathionine β-Synthase (CBS) Domain-containing Pyrophosphatase as a Target for Diadenosine Polyphosphates in Bacteria. The Journal of biological chemistry, 2015, Nov-13, Volume: 290, Issue:46 Topics: Adenine Nucleotides; Amino Acid Sequence; Bacteria; Bacterial Proteins; Clostridium perfringens; Cystathionine beta-Synthase; Dinucleoside Phosphates; Kinetics; Molecular Sequence Data; Moorella; Protein Binding; Protein Structure, Tertiary; Pyrophosphatases	2015
Diadenosine tetra- and pentaphosphates affect contractility and bioelectrical activity in the rat heart via P2 purinergic receptors. Naunyn-Schmiedeberg's archives of pharmacology, 2016, Volume: 389, Issue:3 Topics: Action Potentials; Animals; Dinucleoside Phosphates; Heart; In Vitro Techniques; Male; Myocardial Contraction; Pulmonary Veins; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rats, Wistar; Receptors, Purinergic P2; Suramin	2016
High concentrations of intracellular Ap4A and/or Ap5A in developing Myxococcus xanthus cells inhibit sporulation. Microbiology (Reading, England), 2017, Volume: 163, Issue:1 Topics: Acid Anhydride Hydrolases; Adenosine Triphosphate; Dinucleoside Phosphates; Myxococcus xanthus; Signal Transduction; Spores, Bacterial; Starvation	2017
Identification of Major Enzymes Involved in the Synthesis of Diadenosine Tetraphosphate and/or Adenosine Tetraphosphate in Myxococcus xanthus. Current microbiology, 2018, Volume: 75, Issue:7 Topics: Adenosine; Amino Acyl-tRNA Synthetases; Bacterial Proteins; Biocatalysis; Biosynthetic Pathways; Coenzyme A Ligases; Dinucleoside Phosphates; Lysine-tRNA Ligase; Myxococcus xanthus	2018