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diadenosine tetraphosphate and adenosine monophosphate

diadenosine tetraphosphate has been researched along with adenosine monophosphate in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199011 (35.48)18.7374
1990's10 (32.26)18.2507
2000's6 (19.35)29.6817
2010's2 (6.45)24.3611
2020's2 (6.45)2.80

Authors

AuthorsStudies
Chang, CJ; Geahlen, RL1
Blackburn, GM; Hagemann, J; Hohmeier, N; Lempka, M; Verspohl, EJ1
Ieda, N; Kawaguchi, M; Murakami, T; Nakagawa, H; Ohta, Y; Sekimoto, E1
Kisteneff, E; Kolodny, NH; Rapaport, E; Redfield, C1
Castillo, CJ; Del Valle, M; García, AG; Moro, MA; Sillero, A; Sillero, MA1
Evershed, RP; McLennan, AG; Prescott, M1
Guranowski, A; Holler, E; Jakubowski, H; Just, G1
Delicado, EG; Miras-Portugal, MT; Rodriguez del Castillo, A; Torres, M1
Barnes, LD; Garrison, PN; Mumford, CH; Robinson, AK1
Baril, EF; Coughlin, SA; Zamecnik, PC1
Canales, J; Günther Sillero, MA; Pinto, RM; Sillero, A1
Krishtal, OA; Marchenko, SM; Obukhov, AG; Volkova, TM1
Wahab, SZ; Yang, DC1
Jakob, P; Ogilvie, A1
Gekeler, V; Hamprecht, K; Probst, H1
Belrhali, H; Berthet-Colominas, C; Bösecke, P; Cusack, S; Diat, O; Rasmussen, B; Tukalo, M; Yaremchuk, A1
Miras-Portugal, MT; Mora, F; Pintor, J; Porras, A1
Corton, J; Hardie, DG; Hawley, SA; Shugar, D; Weekes, J1
Hatano, N; Iwata, K; Kimura, T; Kurosaki, Y; Nakajima, H; Nakayama, T; Wada, M; Yamaura, T1
Gomez De Aranda, I; Marti, E; Mateo, J; Miras-Portugal, MT; Rotllan, P; Solsona, C1
Mezzasoma, I; Minelli, A; Moroni, M1
Ogilvie, A; Otto, B1
de Diego, A; Fontes, R; Günther Sillero, MA; Ortiz, B; Sillero, A1
Atencia, EA; Günther Sillero, MA; Montes, M; Sillero, A1
Claes, P; Grobben, B; Roymans, D; Slegers, H; Van Kolen, K1
Bellezza, I; Castellini, C; Liguori, L; Minelli, A; Renieri, T1
Hart, CA; Ismail, TM; McLennan, AG1
Maier, T; Schultz-Heienbrok, R; Sträter, N1
Baykov, AA; Goldman, A; Heikkilä, O; Jämsen, J; Lahti, R; Lehtiö, L; Magretova, NN; Oksanen, E; Salminen, A; Tuominen, H1
Chen, Y; Hou, WT; Jiang, YL; Li, WZ; Zhou, CZ1
Frese, M; Herzog, D; Höpfner, D; Itzen, A; Marx, A; Saumer, P; Yuan, Y1

Reviews

1 review(s) available for diadenosine tetraphosphate and adenosine monophosphate

ArticleYear
Protein-tyrosine kinase inhibition: mechanism-based discovery of antitumor agents.
    Journal of natural products, 1992, Volume: 55, Issue:11

    Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Humans; Protein-Tyrosine Kinases

1992

Other Studies

30 other study(ies) available for diadenosine tetraphosphate and adenosine monophosphate

ArticleYear
Synthetic, nondegradable diadenosine polyphosphates and diinosine polyphosphates: their effects on insulin-secreting cells and cultured vascular smooth muscle cells.
    Journal of medicinal chemistry, 2003, Apr-10, Volume: 46, Issue:8

    Topics: 3T3 Cells; Animals; Cell Division; Cells, Cultured; Dinucleoside Phosphates; In Vitro Techniques; Insulin; Insulin Secretion; Mice; Muscle, Smooth, Vascular; Protein Binding; Rats; Stereoisomerism; Structure-Activity Relationship; Thymidine

2003
Synthesis of Fluorescent Probes Targeting Tumor-Suppressor Protein FHIT and Identification of Apoptosis-Inducing FHIT Inhibitors.
    Journal of medicinal chemistry, 2021, 07-08, Volume: 64, Issue:13

    Topics: Acid Anhydride Hydrolases; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Fluorescent Dyes; Humans; Molecular Structure; Neoplasm Proteins; Structure-Activity Relationship

2021
Ap4A and Ap5A prefer folded unstacked conformations at pH 4-5, in sharp contrast with Ap2A and Ap3A.
    FEBS letters, 1979, Nov-01, Volume: 107, Issue:1

    Topics: Adenine Nucleotides; Adenosine Monophosphate; Dinucleoside Phosphates; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Molecular; Nucleic Acid Conformation

1979
Diadenosine tetraphosphate is co-released with ATP and catecholamines from bovine adrenal medulla.
    Journal of neurochemistry, 1992, Volume: 59, Issue:2

    Topics: Acetylcholine; Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Adrenal Medulla; Animals; Calcium; Catecholamines; Cattle; Chromatography, High Pressure Liquid; Dinucleoside Phosphates; Inosine; Luciferases; Potassium; Tritium

1992
Identification of point of specific enzymic cleavage of P1,P4-bis(5'-adenosyl) tetraphosphate by negative ion FAB mass spectrometry.
    Biomedical & environmental mass spectrometry, 1989, Volume: 18, Issue:6

    Topics: Acid Anhydride Hydrolases; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Artemia; Dinucleoside Phosphates; Mass Spectrometry; Phosphoric Monoester Hydrolases; Physarum

1989
Synthesis of diadenosine 5',5'''-P1,P4-tetraphosphate (AppppA) from adenosine 5'-phosphosulfate and adenosine 5'-triphosphate catalyzed by yeast AppppA phosphorylase.
    Biochemistry, 1988, Apr-19, Volume: 27, Issue:8

    Topics: Adenine Nucleotides; Adenosine Monophosphate; Adenosine Phosphosulfate; Adenosine Triphosphate; Chromatography, High Pressure Liquid; Dinucleoside Phosphates; Kinetics; Nucleotidyltransferases; Saccharomyces cerevisiae; Tritium

1988
Subcellular distribution studies of diadenosine polyphosphates--Ap4A and Ap5A--in bovine adrenal medulla: presence in chromaffin granules.
    Journal of neurochemistry, 1988, Volume: 51, Issue:6

    Topics: Adenosine Diphosphate; Adenosine Kinase; Adenosine Monophosphate; Adenosine Triphosphate; Adenylate Kinase; Adrenal Medulla; Animals; Cattle; Chromaffin Granules; Chromaffin System; Chromatography, High Pressure Liquid; Cytosol; Dinucleoside Phosphates; Phosphoric Monoester Hydrolases

1988
Assay of diadenosine tetraphosphate hydrolytic enzymes by boronate chromatography.
    Analytical biochemistry, 1985, Volume: 144, Issue:1

    Topics: Acid Anhydride Hydrolases; Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Boron Compounds; Chromatography, Ion Exchange; Dinucleoside Phosphates; Phosphoric Diester Hydrolases; Phosphoric Monoester Hydrolases; Physarum

1985
5',5'''-P1, P4 diadenosine tetraphosphate (Ap4A): a putative initiator of DNA replication.
    Cancer investigation, 1985, Volume: 3, Issue:5

    Topics: Acid Anhydride Hydrolases; Adenine Nucleotides; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Carrier Proteins; Cell Division; Dinucleoside Phosphates; DNA; DNA Polymerase II; DNA Replication; HeLa Cells; Humans; Interphase; Phosphoric Monoester Hydrolases; Plants; Tryptophan-tRNA Ligase

1985
Diadenosine tetraphosphate activates cytosol 5'-nucleotidase.
    Biochemical and biophysical research communications, 1986, Jul-16, Volume: 138, Issue:1

    Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Artemia; Cytidine Monophosphate; Cytosol; Dinucleoside Phosphates; Guanosine Monophosphate; Inosine Monophosphate; Kinetics; Nucleotidases; Rats; Ribonucleotides; Xanthine

1986
Receptors for ATP in rat sensory neurones: the structure-function relationship for ligands.
    British journal of pharmacology, 1988, Volume: 95, Issue:4

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; Animals; Dinucleoside Phosphates; Female; In Vitro Techniques; Ligands; Male; Neurons; Nucleotides; Rats; Receptors, Purinergic; Structure-Activity Relationship

1988
Synthesis of diadenosine 5',5''' -P1,P4-tetraphosphate by lysyl-tRNA synthetase and a multienzyme complex of aminoacyl-tRNA synthetases from rat liver.
    The Journal of biological chemistry, 1985, May-10, Volume: 260, Issue:9

    Topics: Adenine Nucleotides; Adenosine Monophosphate; Amino Acyl-tRNA Synthetases; Animals; Dinucleoside Phosphates; Kinetics; Liver; Lysine-tRNA Ligase; Male; Rats; Zinc

1985
Diadenosine 5',5"'-P1,P3-triphosphate in eukaryotic cells: identification and quantitation.
    Analytical biochemistry, 1983, Oct-15, Volume: 134, Issue:2

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Carcinoma, Ehrlich Tumor; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, High Pressure Liquid; Dinucleoside Phosphates; Eukaryotic Cells; Mice

1983
Replicon initiation frequency and intracellular levels of ATP, ADP, AMP and of diadenosine 5',5'''-P1,P4-tetraphosphate in ehrlich ascites cells cultured aerobically and anaerobically.
    Biochemical and biophysical research communications, 1983, Jan-27, Volume: 110, Issue:2

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aerobiosis; Anaerobiosis; Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; Dinucleoside Phosphates; DNA, Neoplasm; Mice; Oxygen; Replicon

1983
The structural basis for seryl-adenylate and Ap4A synthesis by seryl-tRNA synthetase.
    Structure (London, England : 1993), 1995, Apr-15, Volume: 3, Issue:4

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Catalysis; Crystallography, X-Ray; Dinucleoside Phosphates; Manganese; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Protein Conformation; RNA, Transfer, Ser; Serine; Serine-tRNA Ligase; Substrate Specificity; Thermus thermophilus

1995
Dopamine receptor blockade inhibits the amphetamine-induced release of diadenosine polyphosphates, diadenosine tetraphosphate and diadenosine pentaphosphate, from neostriatum of the conscious rat.
    Journal of neurochemistry, 1995, Volume: 64, Issue:2

    Topics: Adenosine; Adenosine Monophosphate; Amphetamine; Animals; Corpus Striatum; Dinucleoside Phosphates; Dopamine Antagonists; Haloperidol; Male; Perfusion; Rats; Rats, Wistar

1995
Activation of rat liver AMP-activated protein kinase by kinase kinase in a purified, reconstituted system. Effects of AMP and AMP analogues.
    European journal of biochemistry, 1994, Feb-01, Volume: 219, Issue:3

    Topics: Adenosine Monophosphate; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Binding Sites; Dinucleoside Phosphates; Enzyme Activation; Formycins; Liver; Molecular Weight; Multienzyme Complexes; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Rats; Ribonucleotides

1994
Disposition of diadenosine 5',5"'-P1,P4-tetraphosphate (Ap4A) in rats.
    Biological & pharmaceutical bulletin, 1995, Volume: 18, Issue:11

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Dinucleoside Phosphates; Half-Life; Injections, Intravenous; Male; Rats; Rats, Wistar

1995
Diadenosine polyphosphate hydrolase from presynaptic plasma membranes of Torpedo electric organ.
    The Biochemical journal, 1997, May-01, Volume: 323 ( Pt 3)

    Topics: Acid Anhydride Hydrolases; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cations, Divalent; Diethyl Pyrocarbonate; Dinucleoside Phosphates; Electric Organ; Enzyme Inhibitors; Hydrogen-Ion Concentration; Kinetics; Nerve Tissue Proteins; Presynaptic Terminals; Pyridoxal Phosphate; Torpedo

1997
Human seminal plasma soluble 5'-nucleotidase: regulatory aspects of the dephosphorylation of nucleoside 5'-monophosphates.
    Biochemical and molecular medicine, 1997, Volume: 61, Issue:1

    Topics: 5'-Nucleotidase; Adenosine Monophosphate; Cytidine Monophosphate; Dinucleoside Phosphates; Energy Metabolism; Guanosine Monophosphate; Humans; Inosine Monophosphate; Male; Phosphorylation; Purine Nucleotides; Semen; Solubility; Uridine Monophosphate; Vanadates

1997
The response of peritoneal macrophages after implantation of several ceramics as measured by the change of ectoenzyme activity.
    Biomaterials, 1998, Volume: 19, Issue:11-12

    Topics: 5'-Nucleotidase; Adenosine Monophosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Aluminum Oxide; Animals; Calcium Compounds; Calcium Phosphates; Ceramics; Dinucleoside Phosphates; Female; Macrophage Activation; Macrophages, Peritoneal; Mice; Oxides; Phosphodiesterase I; Phosphoric Diester Hydrolases; Prostheses and Implants

1998
Dehydroluciferyl-AMP is the main intermediate in the luciferin dependent synthesis of Ap4A catalyzed by firefly luciferase.
    FEBS letters, 1998, Nov-06, Volume: 438, Issue:3

    Topics: Adenosine Monophosphate; Animals; Catalysis; Chromatography, High Pressure Liquid; Coleoptera; Dinucleoside Phosphates; Firefly Luciferin; Luciferases

1998
Several dinucleoside polyphosphates are acceptor substrates in the T4 RNA ligase catalyzed reaction.
    European journal of biochemistry, 2000, Volume: 267, Issue:6

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; Bacteriophage T4; Catalysis; Cytidine Diphosphate; Dinucleoside Phosphates; RNA Ligase (ATP); Substrate Specificity; Viral Proteins

2000
P2Y(AC)(-)-receptor agonists enhance the proliferation of rat C6 glioma cells through activation of the p42/44 mitogen-activated protein kinase.
    British journal of pharmacology, 2001, Volume: 134, Issue:2

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cell Division; Dinucleoside Phosphates; Enzyme Activation; Glioma; Hydrolysis; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Purinergic P2 Receptor Agonists; Pyridoxal Phosphate; Rats; Receptors, Purinergic P2; Thionucleotides; Time Factors; Triazines; Tumor Cells, Cultured

2001
Effects of diadenosine polyphosphates and seminal fluid vesicles on rabbit sperm cells.
    Reproduction (Cambridge, England), 2003, Volume: 125, Issue:6

    Topics: 5'-Nucleotidase; Acrosome Reaction; Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Dinucleoside Phosphates; Male; Microscopy, Electron; Polyphosphates; Rabbits; Seminal Vesicles; Sperm Capacitation; Spermatozoa; Type C Phospholipases

2003
Regulation of dinucleoside polyphosphate pools by the YgdP and ApaH hydrolases is essential for the ability of Salmonella enterica serovar typhimurium to invade cultured mammalian cells.
    The Journal of biological chemistry, 2003, Aug-29, Volume: 278, Issue:35

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; Animals; Bacterial Adhesion; Caenorhabditis elegans; Carbohydrate Metabolism; Cell Division; Cloning, Molecular; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Gene Deletion; Gene Expression Regulation, Bacterial; Genetic Complementation Test; Humans; Kinetics; Mutagenesis; Mutation; N-Glycosyl Hydrolases; Phenotype; Plasmids; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Salmonella typhimurium; Tumor Cells, Cultured; U937 Cells

2003
A large hinge bending domain rotation is necessary for the catalytic function of Escherichia coli 5'-nucleotidase.
    Biochemistry, 2005, Feb-22, Volume: 44, Issue:7

    Topics: 5'-Nucleotidase; Adenosine Diphosphate; Adenosine Monophosphate; Binding Sites; Catalysis; Circular Dichroism; Crystallography, X-Ray; Dinucleoside Phosphates; Disulfides; Dithiothreitol; Escherichia coli Proteins; Hydrolysis; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Oxidation-Reduction; Protein Conformation; Protein Structure, Tertiary; Substrate Specificity

2005
Crystal structures of the CBS and DRTGG domains of the regulatory region of Clostridiumperfringens pyrophosphatase complexed with the inhibitor, AMP, and activator, diadenosine tetraphosphate.
    Journal of molecular biology, 2010, May-07, Volume: 398, Issue:3

    Topics: Adenosine Monophosphate; Amino Acid Sequence; Animals; Bacterial Proteins; Clostridium perfringens; Crystallography, X-Ray; Dimerization; Dinucleoside Phosphates; Enzyme Activators; Enzyme Inhibitors; Models, Molecular; Molecular Sequence Data; Protein Binding; Protein Structure, Quaternary; Protein Structure, Tertiary; Pyrophosphatases; Sequence Alignment

2010
Structures of yeast Apa2 reveal catalytic insights into a canonical AP₄A phosphorylase of the histidine triad superfamily.
    Journal of molecular biology, 2013, Aug-09, Volume: 425, Issue:15

    Topics: Adenosine Monophosphate; Adenosine Triphosphate; Amino Acid Sequence; Catalytic Domain; Crystallography, X-Ray; Dinucleoside Phosphates; DNA Mutational Analysis; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutant Proteins; Nucleotidyltransferases; Protein Binding; Protein Conformation; Saccharomyces cerevisiae; Sequence Alignment

2013
The Alarmone Diadenosine Tetraphosphate as a Cosubstrate for Protein AMPylation.
    Angewandte Chemie (International ed. in English), 2023, 02-13, Volume: 62, Issue:8

    Topics: Adenosine Monophosphate; Dinucleoside Phosphates; Guanosine Pentaphosphate; Humans; Protein Processing, Post-Translational; Proteins

2023