Page last updated: 2024-09-03

diadenosine 5',5''''-p1,p6-hexaphosphate and diadenosine tetraphosphate

diadenosine 5',5''''-p1,p6-hexaphosphate has been researched along with diadenosine tetraphosphate in 27 studies

Compound Research Comparison

Studies
(diadenosine 5',5''''-p1,p6-hexaphosphate)
Trials
(diadenosine 5',5''''-p1,p6-hexaphosphate)
Recent Studies (post-2010)
(diadenosine 5',5''''-p1,p6-hexaphosphate)
Studies
(diadenosine tetraphosphate)
Trials
(diadenosine tetraphosphate)
Recent Studies (post-2010) (diadenosine tetraphosphate)
5205469262

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's17 (62.96)18.2507
2000's7 (25.93)29.6817
2010's3 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Günther Sillero, MA; Sillero, A; Wasternack, C1
Heidenreich, S; Hirsch, J; Kleta, R; Schlatter, E; Schlüter, H; Zidek, W1
Ankorina, I; Haxelmans, S; Kleta, R; Schlatter, E1
Miras-Portugal, MT; Pintor, J1
Dimmick, MA; Hilderman, RH; Jones, GB; Lilien, JE; Tate, DH; Zimmerman, JK1
Borucki, U; Enck, G; Hohage, H; Reinhardt, C; Schlatter, E; Schlüter, H; Zidek, W1
Assmann, G; Beinlich, A; Heidenreich, S; Nofer, JR; Schlüter, H; Tepel, M; Walter, M; Zidek, W1
Bläsius, R; Ogilvie, A; Schulze-Lohoff, E; Sterzel, RB1
Alekseev, AE; Jovanovic, A; Terzic, A1
Jankowski, J; Schlüter, H; Spieker, C; Tepel, M; Zidek, W1
Bachmann, J; Jankowski, J; Ruess, C; Schlüter, H; Tepel, M; Terliesner, J; van der Giet, M; Zidek, W1
Hohage, H; Hollah, P; Khattab, M; Rahn, KH; Schlatter, E1
Hohage, H; Rahn, KH; Schlatter, E; Stachon, A; Stegemann, H1
Brown, SG; Burnstock, G; King, BF; Wildman, SS1
Jankowski, J; Potthoff, W; Schlüter, H; Tepel, M; van der Giet, M; Zidek, W1
Flores, NA; Sheridan, DJ; Stavrou, BM1
Edgecombe, M; Fisher, MJ; McLennan, AG1
Breittmayer, JP; Frelin, C; Vigne, P1
Barenbrock, M; Hausberg, M; Hollah, P; Kosch, M; Letzel, M; Rahn, KH; Schlatter, E1
Blackburn, GM; Cohen, T; Flores, NA; Lawrence, C; Sheridan, DJ; Stavrou, BM1
Barnes, A; Boughtflower, R; Camacho, J; Cousens, D; Marshall, F; Patel, K; Paterson, C1
Janssen, AK; Pelster, F; Rahn, KH; Schlatter, E; Steinmetz, M1
Güngär, N; Jankowski, J; Jankowski, V; Luo, J; Neumann, J; Schlüter, H; Schmitz, W; Zidek, W1
Stavrou, BM1
Chen, FY; Chu, HM; Ko, TP; Wang, AH1
Jankowski, J; Jankowski, V; Schulz, A; Zidek, W1
Anashkin, VA; Baykov, AA; Lahti, R; Orlov, VN; Salminen, A; Tuominen, HK1

Reviews

5 review(s) available for diadenosine 5',5''''-p1,p6-hexaphosphate and diadenosine tetraphosphate

ArticleYear
P2 purinergic receptors for diadenosine polyphosphates in the nervous system.
    General pharmacology, 1995, Volume: 26, Issue:2

    Topics: Animals; Dinucleoside Phosphates; Male; Nervous System; Receptors, Purinergic P2

1995
Adenine dinucleotides: a novel class of signalling molecules.
    Journal of autonomic pharmacology, 1996, Volume: 16, Issue:6

    Topics: Animals; Cell Division; Dinucleoside Phosphates; DNA; Humans; Muscle, Smooth, Vascular; Platelet Activation; Rats; Signal Transduction

1996
Intracellular diadenosine polyphosphates: a novel family of inhibitory ligands of the ATP-sensitive K+ channel.
    Biochemical pharmacology, 1997, Jul-15, Volume: 54, Issue:2

    Topics: Adenosine Triphosphate; Animals; Cell Membrane; Dinucleoside Phosphates; Ion Channel Gating; Islets of Langerhans; Ligands; Myocardium; Polyphosphates; Potassium Channel Blockers; Potassium Channels

1997
The effects of diadenosine polyphosphates on the cardiovascular system.
    Cardiovascular research, 1999, Volume: 42, Issue:1

    Topics: Action Potentials; Animals; Cardiovascular System; Dinucleoside Phosphates; Endothelium, Vascular; Humans; Myocardial Ischemia; Platelet Aggregation Inhibitors; Potassium Channels; Receptors, Purinergic; Second Messenger Systems; Vascular Resistance; Vasodilation

1999
Diadenosine polyphosphates: postulated mechanisms mediating the cardiac effects.
    Current medicinal chemistry. Cardiovascular and hematological agents, 2003, Volume: 1, Issue:2

    Topics: Animals; Cardiovascular System; Dinucleoside Phosphates; Guinea Pigs; Heart; Humans; Myocardial Ischemia; Nitric Oxide; Receptors, Purinergic; Vascular Resistance; Vasoconstrictor Agents; Vasodilation

2003

Other Studies

22 other study(ies) available for diadenosine 5',5''''-p1,p6-hexaphosphate and diadenosine tetraphosphate

ArticleYear
Diadenosine polyphosphates inhibit the action of ribonucleotide reductase on ADP.
    Biochemistry international, 1991, Volume: 23, Issue:1

    Topics: Adenosine Diphosphate; Cell Membrane Permeability; Chromatography, Gel; Chromatography, High Pressure Liquid; Dinucleoside Phosphates; Enzyme Inhibitors; Oxidation-Reduction; Ribonucleotide Reductases; Yeasts

1991
Effects of diadenosine polyphosphates, ATP and angiotensin II on membrane voltage and membrane conductances of rat mesangial cells.
    Pflugers Archiv : European journal of physiology, 1995, Volume: 430, Issue:5

    Topics: Adenosine; Adenosine Triphosphate; Angiotensin II; Animals; Cell Line; Dinucleoside Phosphates; Glomerular Mesangium; Hypertension; Kinetics; Membrane Potentials; Patch-Clamp Techniques; Potassium Channels; Rats; Rats, Inbred SHR; Rats, Inbred WKY

1995
Effects of diadenosine polyphosphates, ATP and angiotensin II on cytosolic Ca2+ activity and contraction of rat mesangial cells.
    Pflugers Archiv : European journal of physiology, 1995, Volume: 430, Issue:5

    Topics: Adenosine Triphosphate; Angiotensin II; Animals; Calcium; Cell Line; Cytosol; Dinucleoside Phosphates; Fura-2; Glomerular Mesangium; Hypertension; Muscle Contraction; Patch-Clamp Techniques; Rats; Rats, Inbred SHR; Rats, Inbred WKY

1995
Adenylated dinucleotide binding to the adenosine 5',5'''-P1,P4-tetraphosphate mouse heart receptor.
    Biochemical and biophysical research communications, 1994, Apr-29, Volume: 200, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Cell Membrane; Dinucleoside Phosphates; Female; In Vitro Techniques; Kinetics; Mice; Models, Molecular; Myocardium; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Thermodynamics

1994
Effects of diadenosine polyphosphates on renal function and blood pressure in anesthetized Wistar rats.
    Journal of the American Society of Nephrology : JASN, 1996, Volume: 7, Issue:8

    Topics: Anesthesia; Animals; Blood Pressure; Bosentan; Cyclooxygenase Inhibitors; Dinucleoside Phosphates; Diuresis; Endothelins; Enzyme Inhibitors; Glomerular Filtration Rate; Indomethacin; Kidney; Male; Natriuresis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Prostaglandins; Rats; Rats, Wistar; Sulfonamides; Vasoconstrictor Agents

1996
Diadenosine polyphosphates induce transplasma membrane calcium influx in cultured glomerular mesangial cells.
    European journal of clinical investigation, 1996, Volume: 26, Issue:12

    Topics: Adenosine Triphosphate; Affinity Labels; Angiotensin II; Animals; Calcium; Cell Membrane; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Glomerular Mesangium; Male; Phospholipase D; Rats; Rats, Inbred WKY; Second Messenger Systems; Suramin; Type C Phospholipases; Vasoconstrictor Agents

1996
Effect of diadenosine polyphosphates on Ca2+ ATPase activity.
    Journal of molecular medicine (Berlin, Germany), 1997, Volume: 75, Issue:9

    Topics: Adenosine Triphosphate; Calcium-Transporting ATPases; Dinucleoside Phosphates; Humans; Structure-Activity Relationship

1997
Diadenosine polyphosphates' action on calcium and vessel contraction.
    American journal of hypertension, 1997, Volume: 10, Issue:12 Pt 1

    Topics: Animals; Calcium; Dinucleoside Phosphates; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred WKY; Vasoconstriction

1997
Effects of diadenosine polyphosphates on systemic and regional hemodynamics in anesthetized rats.
    Kidney & blood pressure research, 1998, Volume: 21, Issue:1

    Topics: Animals; Blood Pressure; Cardiac Output; Dinucleoside Phosphates; Femoral Artery; Hemodynamics; Kidney; Male; Nitroprusside; Norepinephrine; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Regional Blood Flow; Second Messenger Systems; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents

1998
Effects of diadenosine polyphosphates on the intracellular Ca2+ concentration in endothelial cells.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 1998, Volume: 8, Issue:4

    Topics: Adenosine Triphosphate; Angiotensin II; Animals; Arginine Vasopressin; Calcium; Cell Line; Cells, Cultured; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Endothelium, Vascular; Fluorescent Antibody Technique; Humans; Rats; Rats, Inbred WKY

1998
Selectivity of diadenosine polyphosphates for rat P2X receptor subunits.
    European journal of pharmacology, 1999, Feb-12, Volume: 367, Issue:1

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Binding, Competitive; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Membrane Potentials; Oocytes; Purinergic P2 Receptor Agonists; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2X3; Receptors, Purinergic P2X4; RNA, Messenger; Xenopus

1999
High-performance liquid chromatographic assay of the diadenosine polyphosphates in human platelets.
    Analytical biochemistry, 1999, Apr-10, Volume: 269, Issue:1

    Topics: Blood Platelets; Chromatography, High Pressure Liquid; Dinucleoside Phosphates; Humans

1999
Diadenosine polyphosphates and the control of cyclic AMP concentrations in isolated rat liver cells.
    FEBS letters, 1999, Sep-03, Volume: 457, Issue:3

    Topics: Adenosine Triphosphate; Animals; Cyclic AMP; Dinucleoside Phosphates; Glucagon; In Vitro Techniques; Liver; Male; Rats; Rats, Wistar; Receptors, Purinergic P2; Signal Transduction; Thionucleotides

1999
Diadenosine polyphosphates as antagonists of the endogenous P2Y(1) receptor in rat brain capillary endothelial cells of the B7 and B10 clones.
    British journal of pharmacology, 2000, Volume: 129, Issue:7

    Topics: Adenosine Diphosphate; Adenylyl Cyclases; Animals; Brain; Calcium; Cells, Cultured; Clone Cells; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Endothelium, Vascular; Purinergic P2 Receptor Antagonists; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2Y1

2000
A novel assay for determination of diadenosine polyphosphates in human platelets: studies in normotensive subjects and in patients with essential hypertension.
    Journal of hypertension, 2001, Volume: 19, Issue:2

    Topics: Adult; Blood Platelets; Dinucleoside Phosphates; Female; Humans; Hypertension; Male; Reproducibility of Results

2001
Coronary vasomotor and cardiac electrophysiologic effects of diadenosine polyphosphates and nonhydrolyzable analogs in the guinea pig.
    Journal of cardiovascular pharmacology, 2001, Volume: 37, Issue:5

    Topics: Action Potentials; Animals; Coronary Vessels; Dinucleoside Phosphates; Guinea Pigs; Heart; Heart Rate; Hydrolysis; Male; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P1; Receptors, Purinergic P2; Structure-Activity Relationship; Vasoconstrictor Agents; Vasomotor System

2001
Activity of diadenosine polyphosphates at P2Y receptors stably expressed in 1321N1 cells.
    European journal of pharmacology, 2001, Nov-02, Volume: 430, Issue:2-3

    Topics: Adenosine Diphosphate; Calcium; Carbachol; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Gene Expression; Humans; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Tumor Cells, Cultured; Uridine Triphosphate

2001
Vasoactivity of diadenosine polyphosphates in human small mesenteric resistance arteries.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 302, Issue:2

    Topics: Animals; Dinucleoside Phosphates; Humans; In Vitro Techniques; Kinetics; Mesenteric Arteries; Muscle Contraction; Rats; Vascular Resistance

2002
Endogenous diadenosine tetraphosphate, diadenosine pentaphosphate, and diadenosine hexaphosphate in human myocardial tissue.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:5

    Topics: Cholinergic Agents; Chromatography, Affinity; Chromatography, Gel; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cytoplasmic Granules; Dinucleoside Phosphates; Heart; Humans; Myocardium; Potassium Channels; Receptors, Purinergic P2; Receptors, Purinergic P2X; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry, Ultraviolet; Vasoconstriction

2004
Binding and catalysis of Humulus lupulus adenylate isopentenyltransferase for the synthesis of isopentenylated diadenosine polyphosphates.
    FEBS letters, 2010, Sep-24, Volume: 584, Issue:18

    Topics: Alkyl and Aryl Transferases; Catalysis; Dinucleoside Phosphates; Humulus; Mutation; Protein Conformation

2010
Highly sensitive, selective and rapid LC-MS method for simultaneous quantification of diadenosine polyphosphates in human plasma.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2014, Jun-15, Volume: 961

    Topics: Chromatography, High Pressure Liquid; Dinucleoside Phosphates; Humans; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization

2014
Cystathionine β-Synthase (CBS) Domain-containing Pyrophosphatase as a Target for Diadenosine Polyphosphates in Bacteria.
    The Journal of biological chemistry, 2015, Nov-13, Volume: 290, Issue:46

    Topics: Adenine Nucleotides; Amino Acid Sequence; Bacteria; Bacterial Proteins; Clostridium perfringens; Cystathionine beta-Synthase; Dinucleoside Phosphates; Kinetics; Molecular Sequence Data; Moorella; Protein Binding; Protein Structure, Tertiary; Pyrophosphatases

2015