Page last updated: 2024-08-22

diacerein and acetaminophen

diacerein has been researched along with acetaminophen in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's2 (33.33)24.3611
2020's3 (50.00)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Dougados, M; Hochberg, MC1
Rai, J; Sharma, R; Singh, K1
Abdelmageed, ME; Elshal, M1
Harahsheh, E; Hussein, S; Mohamed Kamel, GA1
Jin, L; Li, G; Liang, G; Liang, S; Luo, W; Sun, J; Wang, M; Wang, Y; Yu, T1

Reviews

1 review(s) available for diacerein and acetaminophen

ArticleYear
Pharmacological therapy of osteoarthritis.
    Best practice & research. Clinical rheumatology, 2001, Volume: 15, Issue:4

    Topics: Acetaminophen; Anthraquinones; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Chondroitin Sulfates; Glucosamine; Humans; Meta-Analysis as Topic; Osteoarthritis, Hip; Osteoarthritis, Knee

2001

Trials

1 trial(s) available for diacerein and acetaminophen

ArticleYear
Diacerein as adjuvant to diclofenac sodium in osteoarthritis knee.
    International journal of rheumatic diseases, 2012, Volume: 15, Issue:1

    Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Anthraquinones; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Capsules; Delayed-Action Preparations; Diclofenac; Double-Blind Method; Drug Therapy, Combination; Female; Humans; India; Knee Joint; Male; Middle Aged; Osteoarthritis, Knee; Pain Measurement; Placebos; Prospective Studies; Range of Motion, Articular; Recovery of Function; Surveys and Questionnaires; Time Factors; Treatment Outcome

2012

Other Studies

4 other study(ies) available for diacerein and acetaminophen

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Diacerein counteracts acetaminophen-induced hepatotoxicity in mice via targeting NLRP3/caspase-1/IL-1β and IL-4/MCP-1 signaling pathways.
    Archives of pharmacal research, 2022, Volume: 45, Issue:3

    Topics: Acetaminophen; Animals; Anthraquinones; Caspase 1; Chemical and Drug Induced Liver Injury; Interleukin-4; Liver; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Signal Transduction

2022
Diacerein ameliorates acetaminophen hepatotoxicity in rats via inhibiting HMGB1/TLR4/NF-κB and upregulating PPAR-γ signal.
    Molecular biology reports, 2022, Volume: 49, Issue:7

    Topics: Acetaminophen; Animals; Anthraquinones; Antioxidants; Chemical and Drug Induced Liver Injury; COVID-19; HMGB1 Protein; Humans; Liver; Male; NF-kappa B; PPAR gamma; Rats; Toll-Like Receptor 4

2022
Diacerein protects liver against APAP-induced injury via targeting JNK and inhibiting JNK-mediated oxidative stress and apoptosis.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 149

    Topics: Acetaminophen; Animals; Anthraquinones; Apoptosis; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Hepatocytes; JNK Mitogen-Activated Protein Kinases; Liver; MAP Kinase Kinase 4; Mice; Mice, Inbred C57BL; Oxidative Stress; RNA

2022