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dextropropoxyphene and phenobarbital

dextropropoxyphene has been researched along with phenobarbital in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199027 (84.38)18.7374
1990's0 (0.00)18.2507
2000's3 (9.38)29.6817
2010's2 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Elvidge, JA; Jones, JR; Saljoughian, M1
Kutt, H1
Adamkov, J; Bevilaqua, L; Drobný, M; Fundárek, J; Knéslová, L; Pithová, B; Wolfová, E1
Covault, HP; Hostetler, RM; Lehman, T; Peterson, GR1
Franklin, MR; Roberts, SM1
Christiansen, J; Dam, M; Hansen, BS; Kristensen, CB1
Miller, RR1
Rane, A; Wilson, JT1
Franklin, MR; James, RC1
Baciewicz, AM1
Brown, DB; Fortenberry, JC; Shevlin, LT1
Kutt, H; Penry, JK1
Kutt, H; Verebely, K1
Jick, H1
Debusk, FL; Zavelson, TM1
Pert, CB; Snyder, SH1
Bastos, ML; Jukofsky, D; Mulé, SJ1
Kourounakis, P; Selye, H; Szabo, S1
Cryer, PE; Sode, J1
Banez, RJ; Combs, HF; Decker, WJ; Treuting, JJ1
Culp, HW; Marshall, FJ; McMahon, RE; Ridolfo, AS; Wolen, RL1
Culp, HW; Gibson, WR; Marshall, FJ; McMahon, RE; Miller, WM; Mills, J1
Drobný, M; Fundárek, J; Knéslová, L; Pithová, B1
Hensey, OJ; Poskitt, EM; Smith, CS1
Angelo, H; Brandt, J; Christensen, JM; Dam, M; Hansen, BS; Hvidberg, EF; Lous, P1
Gram, LF; Heltberg, J; Schou, J; Way, WL1
COLLINS, RJ; MACGREGOR, DW; WEEKS, JR1

Reviews

3 review(s) available for dextropropoxyphene and phenobarbital

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Carbamazepine drug interactions.
    Therapeutic drug monitoring, 1986, Volume: 8, Issue:3

    Topics: Carbamazepine; Cimetidine; Dextropropoxyphene; Drug Interactions; Erythromycin; Humans; Isoniazid; Lithium; Phenobarbital; Phenytoin; Primidone; Protein Binding; Troleandomycin; Valproic Acid; Warfarin

1986
Usefulness of blood levels of antiepileptic drugs.
    Archives of neurology, 1974, Volume: 31, Issue:5

    Topics: Anticonvulsants; Carbamazepine; Chloramphenicol; Chlordiazepoxide; Chlorpromazine; Chromatography, Gas; Dextropropoxyphene; Diazepam; Dicumarol; Disulfiram; Drug Interactions; Epilepsy; Ethosuximide; Humans; Isoniazid; Methylphenidate; Phenethylamines; Phenobarbital; Phenylbutazone; Phenytoin; Primidone; Prochlorperazine; Sulfamethizole; Sulfaphenazole; Thiazines

1974

Trials

3 trial(s) available for dextropropoxyphene and phenobarbital

ArticleYear
[Effectiveness of fenalgin SPOFA in lumboischiadic syndrome (author's transl)].
    Bratislavske lekarske listy, 1979, Volume: 71, Issue:4

    Topics: Acetaminophen; Adult; Aspirin; Back Pain; Caffeine; Clinical Trials as Topic; Codeine; Dextropropoxyphene; Drug Combinations; Female; Humans; Male; Middle Aged; Phenobarbital; Sciatica; Syndrome

1979
[DP-Neuralgen. Clinical trials in patients with the radicular syndrome].
    Casopis lekaru ceskych, 1983, Jan-21, Volume: 122, Issue:3

    Topics: Adult; Analgesics; Aspirin; Back Pain; Caffeine; Clinical Trials as Topic; Codeine; Dextropropoxyphene; Double-Blind Method; Drug Combinations; Female; Humans; Intervertebral Disc Displacement; Male; Middle Aged; Phenacetin; Phenobarbital

1983
Influence of dextropropoxyphene on steady state serum levels and protein binding of three anti-epileptic drugs in man.
    Acta neurologica Scandinavica, 1980, Volume: 61, Issue:6

    Topics: Adolescent; Adult; Aged; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Clinical Trials as Topic; Dextropropoxyphene; Drug Interactions; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Protein Binding

1980

Other Studies

26 other study(ies) available for dextropropoxyphene and phenobarbital

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Catalytic tritiation of drugs and analysis of the tritium distribution by 3H n.m.r. spectroscopy.
    The Journal of pharmacy and pharmacology, 1979, Volume: 31, Issue:8

    Topics: Amphetamine; Catalysis; Dextropropoxyphene; Imipramine; Isotope Labeling; Magnetic Resonance Spectroscopy; Phenobarbital; Phenytoin; Propranolol; Tritium

1979
Interactions of antiepileptic drugs.
    Epilepsia, 1975, Volume: 16, Issue:2

    Topics: Anti-Infective Agents; Anticonvulsants; Benzodiazepines; Biotransformation; Blood Proteins; Carbamazepine; Dextropropoxyphene; Dicumarol; Disulfiram; Drug Interactions; Ethosuximide; Humans; Intestinal Absorption; Isoniazid; Methylphenidate; Phenethylamines; Phenobarbital; Phenothiazines; Phenytoin; Primidone; Protein Binding; Thiazines

1975
Acute inhibition of oxidative drug metabolism by propoxyphene (Darvon).
    Biochemical pharmacology, 1979, Jun-01, Volume: 28, Issue:11

    Topics: Animals; Cytochrome P-450 Enzyme System; Dextropropoxyphene; Enzyme Induction; Liver; Male; Mice; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Proadifen; Proteins

1979
Modification of hepatic microsomal oxidative drug metabolism in rats by the opiate maintenance drugs acetylmethadol, propoxyphene, and methadone.
    Life sciences, 1979, Sep-03, Volume: 25, Issue:10

    Topics: Animals; Cytochrome P-450 Enzyme System; Dextropropoxyphene; Male; Methadone; Methadyl Acetate; Microsomes, Liver; Phenobarbital; Proadifen; Rats; Structure-Activity Relationship

1979
Interaction between carbamazepine and propoxyphene in man.
    Acta neurologica Scandinavica, 1977, Volume: 56, Issue:6

    Topics: Adolescent; Adult; Carbamazepine; Dextropropoxyphene; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Trigeminal Neuralgia

1977
Effects of smoking on drug action.
    Clinical pharmacology and therapeutics, 1977, Volume: 22, Issue:5 Pt 2

    Topics: Adult; Aged; Aging; Alcohol Drinking; Dextropropoxyphene; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Pharmacology; Phenobarbital; Sex Factors; Smoking; Tranquilizing Agents

1977
Clinical pharmacokinetics in infants and children.
    Clinical pharmacokinetics, 1976, Volume: 1, Issue:1

    Topics: Aging; Body Water; Carbamazepine; Child; Child, Preschool; Clindamycin; Dextropropoxyphene; Diazoxide; Dicloxacillin; Digoxin; Ethosuximide; Humans; Infant; Infant, Newborn; Kidney; Kinetics; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Propranolol; Sulfonamides; Tetracycline; Theophylline

1976
Comparisons of the formation of cytochrome P-450 complexes absorbing at 455 nm in rabbit and rat microsomes.
    Biochemical pharmacology, 1975, Apr-15, Volume: 24, Issue:8

    Topics: Amphetamine; Animals; Benzphetamine; Cytochrome P-450 Enzyme System; Dextropropoxyphene; In Vitro Techniques; Male; Microsomes, Liver; Oxidation-Reduction; Phenobarbital; Proadifen; Rabbits; Rats

1975
Analysis of drug involvement in traffic fatalities in Alabama.
    The American journal of drug and alcohol abuse, 1986, Volume: 12, Issue:3

    Topics: Accidents, Traffic; Alabama; Cannabinoids; Dextropropoxyphene; Diazepam; Ethanol; Humans; Methaqualone; Phenobarbital; Substance-Related Disorders

1986
Metabolism of diphenylhydantoin by rat liver microsomes. I. characteristics of the reaction.
    Biochemical pharmacology, 1970, Volume: 19, Issue:3

    Topics: Adenosine Triphosphate; Animals; Azides; Biotransformation; Chlordiazepoxide; Chlorpromazine; Dextropropoxyphene; Diazepam; Diethylstilbestrol; Dimenhydrinate; Disulfiram; Hydantoins; Hydrogen-Ion Concentration; In Vitro Techniques; Isoniazid; Kinetics; Male; Methylene Blue; Microsomes, Liver; NAD; NADP; Oxygen; Phenobarbital; Phenytoin; Proadifen; Prochlorperazine; Rats; Sodium; Temperature

1970
Smoking and clinical drug effects.
    The Medical clinics of North America, 1974, Volume: 58, Issue:5

    Topics: Age Factors; Chlordiazepoxide; Chlorpromazine; Dextropropoxyphene; Diazepam; Female; Humans; Male; Middle Aged; Phenobarbital; Sleep Wake Disorders; Smoking

1974
Acute dextropropoxyphene hydrochloride (Darvon) poisoning.
    Pediatrics, 1973, Volume: 52, Issue:2

    Topics: Adolescent; Brain Damage, Chronic; Dextropropoxyphene; Diazepam; Female; Humans; Nalorphine; Phenobarbital; Phenytoin; Poisoning; Respiratory Tract Diseases; Seizures; Suicide; Ventilators, Mechanical

1973
Opiate receptor: demonstration in nervous tissue.
    Science (New York, N.Y.), 1973, Mar-09, Volume: 179, Issue:4077

    Topics: Analgesics; Animals; Atropine; Binding, Competitive; Brain; Carbachol; Codeine; Colchicine; Dextromethorphan; Dextropropoxyphene; Guinea Pigs; Histamine; Intestinal Mucosa; Levallorphan; Methadone; Mice; Morphine; Nalorphine; Naloxone; Phenazocine; Phenobarbital; Rats; Receptors, Drug; Serotonin; Tritium

1973
Routine identification of drugs of abuse in human urine. 3. Differential elution of the XAD-2 resin.
    Journal of chromatography, 1973, Jun-27, Volume: 81, Issue:1

    Topics: Amitriptyline; Amphetamine; Barbiturates; Chromatography, Thin Layer; Dextropropoxyphene; Humans; Hydrogen-Ion Concentration; Methods; Pharmaceutical Preparations; Phenobarbital; Phenylpropanolamine; Phenytoin; Quinine; Resins, Plant; Solvents; Substance-Related Disorders

1973
Effect of various steroids and nonsteroidal microsomal enzyme inducers upon propoxyphene intoxication.
    Neuroendocrinology, 1972, Volume: 9, Issue:5

    Topics: Animals; Dextropropoxyphene; Enzyme Induction; Estradiol; Female; Phenobarbital; Phenytoin; Poisoning; Prednisolone; Rats; Thyroxine; Triamcinolone

1972
Drug interference with measurement of adrenal hormones in urine: analgesics and tranquilizer-sedatives.
    Annals of internal medicine, 1971, Volume: 75, Issue:5

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acetaminophen; Adrenal Cortex Hormones; Adult; Analgesics; Aspirin; Catecholamines; Chlordiazepoxide; Colorimetry; Dextropropoxyphene; Diazepam; Diphenhydramine; Drug Interactions; Fluorometry; Humans; Hypnotics and Sedatives; Male; Pentazocine; Phenobarbital; Tranquilizing Agents

1971
Dialysis of drugs against activated charcoal.
    Toxicology and applied pharmacology, 1971, Volume: 18, Issue:3

    Topics: Adsorption; Amitriptyline; Aspirin; Charcoal; Chlordiazepoxide; Chloroquine; Dextroamphetamine; Dextropropoxyphene; Dialysis; Diazepam; Glutethimide; Meprobamate; Methaqualone; Models, Biological; Pentazocine; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Salicylates; Secobarbital; Time Factors

1971
The fate of radiocarbon-labeled propoxyphene in rat, dog, and human.
    Toxicology and applied pharmacology, 1971, Volume: 19, Issue:3

    Topics: Animals; Bile; Carbon Isotopes; Chromatography, Thin Layer; Dealkylation; Dextropropoxyphene; Dogs; Half-Life; Humans; Male; Mass Spectrometry; Naphthalenes; Phenobarbital; Rats; Sulfonic Acids

1971
Demethylation studies. VI. The inhibition of hepatic microsomal oxygenation by 2,4-dichloro(6-phenylphenoxy)ethylamine and related compounds.
    Journal of medicinal chemistry, 1969, Volume: 12, Issue:2

    Topics: Aminopyrine; Amitriptyline; Animals; Butylamines; Carbamates; Carbon Isotopes; Dextropropoxyphene; Dogs; Ethylamines; Hexobarbital; Imipramine; In Vitro Techniques; Liver; Male; Mice; Microsomes; Morphinans; Naphthalenes; Nitriles; Phenethylamines; Phenobarbital; Propylamines; Rats

1969
Alcohol, other drugs and the fetus.
    Developmental medicine and child neurology, 1982, Volume: 24, Issue:5

    Topics: Abnormalities, Drug-Induced; Carbamazepine; Dextropropoxyphene; Diazepam; Drug Synergism; Female; Fetal Alcohol Spectrum Disorders; Fetus; Humans; Infant, Newborn; Male; Phenobarbital; Phenytoin; Pregnancy

1982
d-Propoxyphene single dose kinetics in a subject taking phenobarbital.
    Acta pharmacologica et toxicologica, 1980, Volume: 46, Issue:5

    Topics: Dextropropoxyphene; Drug Interactions; Half-Life; Humans; Kinetics; Phenobarbital

1980
AN ATTEMPT TO DEMONSTRATE CEILING EFFICACY OF ANALGESICS IN RATS.
    Archives internationales de pharmacodynamie et de therapie, 1964, Jan-01, Volume: 147

    Topics: Aminopyrine; Amphetamine; Amphetamines; Analgesics; Aspirin; Barbiturates; Chlordiazepoxide; Chlorpromazine; Codeine; Dextropropoxyphene; Diphenhydramine; Meperidine; Meprobamate; Methadone; Morphine; Pharmacology; Phenobarbital; Rats; Rectum; Research; Toxicology

1964