Page last updated: 2024-09-04

dexmethylphenidate and methylphenidate

dexmethylphenidate has been researched along with methylphenidate in 3 studies

Compound Research Comparison

Studies
(dexmethylphenidate)
Trials
(dexmethylphenidate)
Recent Studies (post-2010)
(dexmethylphenidate)
Studies
(methylphenidate)
Trials
(methylphenidate)
Recent Studies (post-2010) (methylphenidate)
10047,7831,6982,693

Protein Interaction Comparison

ProteinTaxonomydexmethylphenidate (IC50)methylphenidate (IC50)
Sodium-dependent noradrenaline transporter Homo sapiens (human)0.061
Sodium-dependent dopamine transporterRattus norvegicus (Norway rat)0.083
Sodium-dependent serotonin transporterHomo sapiens (human)5.1
Sodium-dependent dopamine transporter Homo sapiens (human)0.079

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bierer, DE; Perel, JM; Reiter, CT; Sapko, MT; Thai, DL1
Blundell, P; Madras, BK; Meltzer, PC; Wang, P1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

1 review(s) available for dexmethylphenidate and methylphenidate

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

2 other study(ies) available for dexmethylphenidate and methylphenidate

ArticleYear
Asymmetric synthesis and pharmacology of methylphenidate and its para-substituted derivatives.
    Journal of medicinal chemistry, 1998, Feb-12, Volume: 41, Issue:4

    Topics: Animals; Brain; Dopamine; Indicators and Reagents; Isomerism; Kinetics; Male; Methylphenidate; Molecular Conformation; Molecular Structure; Motor Activity; Norepinephrine; Organ Specificity; Rats; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship; Synaptosomes

1998
Synthesis and evaluation of dopamine and serotonin transporter inhibition by oxacyclic and carbacyclic analogues of methylphenidate.
    Journal of medicinal chemistry, 2003, Apr-10, Volume: 46, Issue:8

    Topics: Animals; Binding, Competitive; Carrier Proteins; Caudate Nucleus; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; In Vitro Techniques; Macaca fascicularis; Macaca mulatta; Male; Membrane Glycoproteins; Membrane Transport Modulators; Membrane Transport Proteins; Methylphenidate; Nerve Tissue Proteins; Phenylacetates; Putamen; Pyrans; Radioligand Assay; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Structure-Activity Relationship

2003